Nestler, J.J.NestlerMorschhauser, A.A.MorschhauserOtto, T.T.OttoKoger, B.B.KogerBrandenburg, A.A.BrandenburgWunderlich, K.K.WunderlichEhrentreich-Förster, E.E.Ehrentreich-FörsterBier, F.F.F.F.BierGessner, T.T.Gessner2022-03-112022-03-112010https://publica.fraunhofer.de/handle/publica/369172The paper describes a low-cost microfluidic platform with integrated micropumps and optical biosensor for the development of miniaturized assays for in-vitro diagnostic and point-of-care applications. The platform consists of disposable microfluidic cartridges incorporating all parts necessary for carrying out immunoassays (including reagents) as well as a readout instrument providing both the optical, fluorescence based readout and the electrical interface for pump control. The feasibility of the system for running immunoassays is demonstrated by a CRP and PSA based assay carried out completely inside such a cartridge.en621610620Highly-integrated, low-cost in-vitro diagnostic platform for miniaturized assay developmentconference paper