Fasold, MarioMarioFasoldLangenberger, DavidDavidLangenbergerBinder, HansHansBinderStadler, Peter F.Peter F.StadlerHoffmann, SteveSteveHoffmann2022-03-042022-03-042011https://publica.fraunhofer.de/handle/publica/22626710.1093/nar/gkr3572-s2.0-79960019676Small non-coding RNAs (ncRNAs) such as microRNAs, snoRNAs and tRNAs are a diverse collection of molecules with several important biological functions. Current methods for high-throughput sequencing for the first time offer the opportunity to investigate the entire ncRNAome in an essentially unbiased way. However, there is a substantial need for methods that allow a convenient analysis of these overwhelmingly large data sets. Here, we present DARIO, a free web service that allows to study short read data from small RNA-seq experiments. It provides a wide range of analysis features, including quality control, read normalization, ncRNA quantification and prediction of putative ncRNA candidates. The DARIO web site can be accessed at http://dario.bioinf.uni- leipzig.de/.enncRNA610572journal article