Organic groupings play an important role for the preparation of glasses by the sol-gel route. They are responsible for the solubility of precursors, interact during the polycondensation process, the drying and ageing step and during firing. For processing, important parameters e.g. hydrolysis rates and the SiOH formation can be controlled by proper choice of the hydrolysable group. If organics remain in the glass network, remarkable changes of properties (density, hardness, refractive index) occur.