Granulomatous dermatitis and mastitis in two SPF rats associated with a slowly growing Staphylococcus aureus - a case report
An isolated occurence of multifocal severe granulomatous dermatitis and mastitis accompanied by extensive calfications is described in 2 female Sprague-Dawley, SPF breeding rats. Poorly growing Staphylococcus areus of uncertain lysotype (probably lysotype II) was isolated from the lesion of both rats. The source of infection could not be determined. No further cases in the closed barrier maintained breeding colony occured in the following 7 months. Difficulties in interpreting these findings and the practical cosequences relating to the hygenic status of the barrier breeding colony are discussed.