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Strong bonding of corneal incisions using a noncontact fiber-optic laser soldering method

: Basov, Svetlana; Varssano, David; Platkov, Max; Gabay,Ilan; Rosner, Mordechai; Barequet, Irina; Rattunde, Marcel; Wagner, Joachim; Harlev, Mickey; Ofer, Doron; Nisky, Ilan; Danker, Yair; Katzir, Abraham

Volltext urn:nbn:de:0011-n-5751759 (1.3 MByte PDF)
MD5 Fingerprint: 142a1c5c629dad6113b2897565a9d203
Erstellt am: 9.7.2020

Journal of biomedical optics 24 (2019), Nr.12, Art. 128002, 9 S.
ISSN: 1083-3668
ISSN: 1560-2281
Zeitschriftenaufsatz, Elektronische Publikation
Fraunhofer IAF ()
infrared; laser soldering; laser bonding; albumin; cornea; optical fibers

Suturing of corneal incisions requires significant skill. We demonstrate a noncontact method that will simplify the bonding process. 5-mm-long penetrating vertical and slanted incisions were made in corneas of eyes, extracted from dead piglets. A fiber-optic laser system was used for laser soldering of the incisions, under close temperature control, using albumin solder. The burst-pressure PB immediately after the soldering was found to be PB ≈92 and 875 mmHg, for vertical and slanted incisions, respectively. PB=875 mmHg is an exceptionally high figure, ≈10 times the clinically acceptable value for sutured incisions. Laser soldering was then performed on penetrating incisions made in the corneas of live healthy piglets, of weight ≈10 Kg. After a healing period,the eyes were extracted,and the corneas were examined by histopathology and by optical coherence tomography. Our method immediately generated watertight and strong bonding without noticeable corneal shape distortion. These results would be beneficial for cataract surgery and for corneal transplantations. The fiber-optic system makes it much easier to bond corneal incisions. In the future, laser soldering could be automated and efficiently used by less experienced surgeons, thereby reducing the workload on the experienced ones.