Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2020Detection of biomarkers to differentiate endocrine disruption from hepatotoxicity in zebrafish (Danio rerio) using proteomics
Ayobahan, Steve U.; Eilebrecht, Sebastian; Baumann, Lisa; Teigeler, Matthias; Hollert, Henner; Kalkhof, Stefan; Eilebrecht, Elke; Schäfers, Christoph
Zeitschriftenaufsatz
2020Optimizing product quality in molecular farming
Schiermeyer, Andreas
Zeitschriftenaufsatz
2020Retrospective analysis of cyclic volatile methylsiloxanes in archived German fish samples covering a period of two decades
Radermacher, Georg; Rüdel, Heinz; Wesch, Charlotte; Böhnhardt, Anna; Koschorreck, Jan
Zeitschriftenaufsatz
20193D Printed Modular Immunofiltration Columns for Frequency Mixing-Based Multiplex Magnetic Immunodetection
Achtsnicht, S.; Tödter, J.; Niehues, J.; Telöken, M.; Offenhäusser, A.; Krause, H.J.; Schröper, F.
Zeitschriftenaufsatz
20194 Ds in health research - working together toward rapid precision medicine
Niederberger, E.; Parnham, M.J.; Maas, J.; Geisslinger, G.
Zeitschriftenaufsatz
2019α-Amino Diphenyl Phosphonates as Novel Inhibitors of Escherichia coli ClpP Protease
Moreno-Cinos, C.; Sassetti, E.; Salado, I.G.; Witt, G.; Benramdane, S.; Reinhardt, L.; Cruz, C.D.; Joossens, J.; Veken, P. Van der; Brötz-Oesterhe, H.; Tammela, P.; Winterhalter, M.; Gribbon, P.; Windshügel, B.; Augustyns, K.
Zeitschriftenaufsatz
2019Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform
Moraes, C.B.; Witt, G.; Kuzikov, M.; Ellinper, B.; Calogeropoulou, T.; Prousis, K.C.; Mangani, S.; Pisa, F. di; Landi, G.; Dello Lacono, L.; Pozzi, C.; Freitas, L.H.; Pascoalino, B.D.; Bertolacini, C.P.; Behrens, B.; Keminer, O.; Leu, J.; Wolf, M.; Reinshagen, J.; Cordeiro-da-Silva, A.; Santarem, N.; Venturelli, A.; Wrigley, S.; Karunakaran, D.; Kebede, B.; Pohner, I.; Muller, W.; Panecka-Hofman, J.; Wade, R.C.; Fenske, M.; Clos, J.; Alunda, J.M.; Corral, M.J.; Uliassi, E.; Bolognesi, M.L.; Linciano, P.; Quotadamo, A.; Ferrari, S.; Santucci, M.; Borsari, C.; Costi, M.P.; Gul, S.
Zeitschriftenaufsatz
2019Achievement Of CDAPSA Low Disease Activity Or Remission Is Associated With Control Of Articular And Extra-Articular Manifestations Of Active Psoriatic Arthritis In Subjects Treated With Apremilast
Coates, L.C.; Mease, P.J.; Behrens, F.; Orbai, A.M.; Ogdie, A.; Brunori, M.; Teng, L.; Guerette, B.; Smolen, J.S.
Abstract
2019Activated Cross-linked Agarose for the Rapid Development of Affinity Chromatography Resins - Antibody Capture as a Case Study
Knödler, M.; Rühl, C.; Opdensteinen, P.; Buyel, J.F.
Zeitschriftenaufsatz
2019Activation of Caspase-6 Is Promoted by a Mutant Huntingtin Fragment and Blocked by an Allosteric Inhibitor Compound
Ehrnhoefer, D.E.; Skotte, N.H.; Reinshagen, J.; Qiu, X.; Windshügel, B.; Jaishankar, P.; Ladha, S.; Petina, O.; Khankischpur, M.; Nguyen, Y.T.N.; Caron, N.S.; Razeto, A.; Meyer zu Rheda, M.; Deng, Y.; Huynh, K.T.; Wittig, I.; Gribbon, P.; Renslo, A.R.; Geffken, D.; Gul, S.; Hayden, M.R.
Zeitschriftenaufsatz
2019ADAM15 in Apoptosis Resistance of Synovial Fibroblasts
Janczi, T.; Böhm, B.B.; Fehrl, Y.; DeGiacomo, P.; Kinne, R.W.; Burkhardt, H.
Zeitschriftenaufsatz
2019Addition or removal of concomitant methotrexate alters adalimumab effectiveness in rheumatoid arthritis but not psoriatic arthritis
Behrens, F.; Koehm, M.; Schwaneck, E.C.; Schmalzing, M.; Wittig, B.M.; Gnann, H.; Greger, G.; Tony, H.P.; Burkhardt, H.
Zeitschriftenaufsatz
2019Advanced in silico modeling explains pharmacokinetics and biodistribution of temoporfin nanocrystals in humans
Jablonka, L.; Ashtikar, M.; Gao, G.; Jung, F.; Thurn, M.; Preuß, A.; Scheglmann, D.; Albrecht, V.; Röder, B.; Wacker, M.G.
Zeitschriftenaufsatz
2019Aeration and Shear Stress Are Critical Process Parameters for the Production of Oncolytic Measles Virus
Grein, T.A.; Loewe, D.; Dieken, H.; Weidner, T.; Salzig, D.; Czermak, P.
Zeitschriftenaufsatz
2019Aktuelle Therapie der Psoriasisarthritis
Köhm, M.; Behrens, F.
Zeitschriftenaufsatz
2019Alternativen zum Wachstum
Schäfers, Christoph; Bette, Kristina; Herrmann, Florian; Nawroth, Georg
Aufsatz in Buch
2019Analyses of association of psoriatic arthritis and psoriasis vulgaris with functional NCF1 variants
Löhr, S.; Ekici, A.B.; Uebe, S.; Büttner, C.; Köhm, M.; Behrens, F.; Böhm, B.; Sticherling, M.; Schett, G.; Simon, D.; Mössner, R.; Nimeh, A.; Oji, V.; Assmann, G.; Rech, J.; Holmdahl, R.; Burkhardt, H.; Reis, A.; Hüffmeier, U.
Zeitschriftenaufsatz
2019Antibacterial and antifungal activity of defensins from the Australian paralysis tick, Ixodes holocyclus
Cabezas-Cruz, A.; Tonk, M.; Bleackley, M.R.; Valdes, J.J.; Barrero, R.A.; Hernández-Jarguín, A.; Moutailler, S.; Vilcinskas, A.; Richard-Forget, F.; Anderson, M.A.; Rodriguez-Valle, M.
Zeitschriftenaufsatz
2019Antibiotic-producing beneficial bacteria in the gut of the burying beetle nicrophorus vespilloides
Heise, P.; Liu, Y.; Degenkolb, T.; Vogel, H.; Schäberle, T.F.; Vilcinskas, A.
Zeitschriftenaufsatz
2019The Antisteatotic and Hypolipidemic Effect of Insect Meal in Obese Zucker Rats is Accompanied by Profound Changes in Hepatic Phospholipid and 1-Carbon Metabolism
Meyer, S.; Gessner, D.K.; Wen, G.; Most, E.; Liebisch, G.; Zorn, H.; Ringseis, R.; Eder, K.
Zeitschriftenaufsatz
2019Application of adverse outcome pathways and quantitative in vitro-in vivo extrapolation (QIVIVE) modelling for risk assessment based on in vitro data
Mally, A.; Birk, B.; Fiore, S. di; Ellinger, B.; Jarzina, S.; Reiser, P.; Taverne, F.; Kramer, N.
Abstract
2019Association analyses of functional NCF1 variants in psoriatic arthritis and psoriasis vulgaris
Hüffmeier, U.D.; Löhr, S.; Ekici, A.B.; Uebe, S.; Köhm, M.; Behrens, F.; Böhm, B.; Sticherling, M.; Schett, G.; Mössner, R.; Nimeh, A.; Assmann, G.; Rech, J.; Oji, V.; Holmdahl, R.; Burkhardt, H.; Reis, A.
Abstract
2019Bioconcentration studies with the freshwater amphipod Hyalella azteca: Are the results predictive of bioconcentration in fish?
Schlechtriem, Christian; Kampe, Sebastian; Bruckert, Hans-Jörg; Bischof, Ina; Ebersbach, Ina; Kosfeld, Verena; Kotthoff, Matthias; Schäfers, Christoph; L’Haridon, Jacques
Zeitschriftenaufsatz
2019Bioconcentration, metabolism and spatial distribution of 14C‐labelled laurate in the freshwater amphipod Hyalella Azteca
Raths, Johannes; Kühr, Sebastian; Schlechtriem, Christian
Zeitschriftenaufsatz
2019Biodegradation of Volatile Chemicals in Soil: Separating Volatilization and Degradation in an Improved Test Setup (OECD 307)
Shrestha, Prasit; Meisterjahn, Boris; Klein, Michael; Mayer, Philipp; Birch, Heidi; Hughes, Christopher B.; Hennecke, Dieter
Zeitschriftenaufsatz
2019Biodegradation testing of hydrophobic and volatile organic chemicals
Shrestha, Prasit
: Hennecke, Dieter; Mayer, Philipp
Dissertation
2019Biosynthesis of Stereoisomers of Dill Ether and Wine Lactone by Pleurotus sapidus
Trapp, T.; Kirchner, T.; Birk, F.; Fraatz, M.A.; Zorn, H.
Zeitschriftenaufsatz
2019Biosynthetic Basis for Structural Diversity of Aminophenylpyrrole-Derived Alkaloids
Linares-Otoya, L.; Liu, Y.; Linares-Otoya, V.; Armas-Mantilla, L.; Crüsemann, M.; Ganoza-Yupanqui, M.L.; Campos-Florian, J.; König, G.M.; Schäberle, T.F.
Zeitschriftenaufsatz
2019Canakinumab For The Treatment Of Adult Onset Still's Disease To Achieve Reduction Of Arthritic Manifestation At Week 12: An Investigator-Initiated Multi-Centre, Placebo-Controlled Study (Consider)
Kedor, C.; Listing, J.; Zernicke, J.; Weiss, A.; Behrens, F.; Blank, N.; Henes, J.; Kekow, J.; Rubbert-Roth, A.; Schulze-Koops, H.; Seipelt, E.; Specker, C.; Feist, E.
Abstract
2019Cancer-induced inflammation and inflammation-induced cancer in colon: A role for S1P lyase
Schwiebs, A.; Herrero San Juan, M.; Schmidt, K.G.; Wiercinska, E.; Anlauf, M.; Ottenlinger, F.; Thomas, D.; Elwakeel, E.; Weigert, A.; Farin, H.F.; Bonig, H.; Scholich, K.; Geisslinger, G.; Pfeilschifter, J.M.; Radeke, H.H.
Zeitschriftenaufsatz
2019Carboxylic acid consumption and production by Corynebacterium glutamicum
Conrady, M.; Lemoine, A.; Limberg, M.H.; Oldiges, M.; Neubauer, P.; Junne, S.
Zeitschriftenaufsatz
2019Ceramides as Novel Disease Biomarkers
Kurz, J.; Parnham, M.J.; Geisslinger, G.; Schiffmann, S.
Zeitschriftenaufsatz
2019Characterization Of Patients With Inflammatory Bowel Disease In The Ankylosing Spondylitis Cohort Prior And During Adalimumab Treatment: Data From A Large German Non-Interventional Study
Köhm, M.; Schmalzing, M.; Schwaneck, E.C.; Gnann, H.; Tony, H.P.; Greger, G.; Boas, A.; Burkhardt, H.; Behrens, F.
Abstract
2019Chronic Hypoxia Enhances β-Oxidation-Dependent Electron Transport via Electron Transferring Flavoproteins
Fuhrmann, D.C.; Olesch, C.; Kurrle, N.; Schnütgen, F.; Zukunft, S.; Fleming, I.; Brüne, B.
Zeitschriftenaufsatz
2019Circular synthesized CRISPR/Cas gRNAs for functional interrogations in the coding and noncoding genome
Wegner, M.; Diehl, V.; Bittl, V.; Bruyn, R. de; Wiechmann, S.; Matthess, Y.; Heber, M.; Hayes, M.G.B.; Schaubeck, S.; Benner, C.; Heinz, S.; Bremm, A.; Dikic, I.; Ernst, A.; Kaulich, M.
Zeitschriftenaufsatz
2019Clinical Usefulness of Self-Rated Olfactory Performance - A Data Science-Based Assessment of 6000 Patients
Lötsch, J.; Hummel, T.
Zeitschriftenaufsatz
2019Closing gaps for environmental risk screening of engineered nanomaterials
Kühnel, D.; Nickel, C.; Hellack, B.; Zalm, E. van der; Kussatz, C.; Herrchen, M.; Meisterjahn, B.; Hund-Rinke, K.
Zeitschriftenaufsatz
2019Clot derived contaminants in transplanted cells enhance inflammation at peri-stroke area after bone marrow mononuclear cell transplantation in murine stroke model
Taura, A.; Ogawa, Y.; Okinaka, Y.; Takeuchi, Y.; Boltze, J.; Gul, S.; Claussen, C.; Taguchi, A.
Abstract
2019Clot-Derived Contaminants in Transplanted Bone Marrow Mononuclear Cells Impair the Therapeutic Effect in Stroke
Okinaka, Y.; Kikuchi-Taura, A.; Takeuchi, Y.; Ogawa, Y.; Boltze, J.; Gul, S.; Claussen, C.; Taguchi, A.
Zeitschriftenaufsatz
2019Co-cultivation: A powerful tool for insulin-producing beta cell manufacturing
Petry, F.; Czermak, P.; Salzig, D.
Abstract
2019Combination of membrane-based and chromatographic methods to achieve pure and concentrated oncolytic measles viruses
Loewe, D.; Dieken, H.; Grein, T.; Salzig, D.; Czermak, P.
Abstract
2019A combined FSTRA-shotgun proteomics approach to identify molecular changes in zebrafish upon chemical exposure
Ayobahan, S.U.; Eilebrecht, E.; Kotthoff, M.; Baumann, L.; Eilebrecht, S.; Teigeler, M.; Hollert, H.; Kalkhof, S.; Schäfers, C.
Zeitschriftenaufsatz
2019A Combined Ultrafiltration/Diafiltration Step Facilitates the Purification of Cyanovirin-N From Transgenic Tobacco Extracts
Opdensteinen, P.; Clodt, J.I.; Müschen, C.R.; Filiz, V.; Buyel, J.F.
Zeitschriftenaufsatz
2019Comparative estrogenicity of endogenous, environmental and dietary estrogens in pregnant women II
Pande, P.; Fleck, S.C.; Twaddle, N.C.; Churchwell, M.I.; Doerge, D.R.; Teeguarden, J.G.
Zeitschriftenaufsatz
2019Comparative multi-generation study on long-term effects of pristine and wastewater-borne silver and titanium dioxide nanoparticles on key lifecycle parameters in Daphnia magna
Hartmann, S.; Louch, R.; Zeumer, R.; Steinhoff, B.; Mozhayeva, D.; Engelhard, C.; Schönherr, H.; Schlechtriem, C.; Witte, K.
Zeitschriftenaufsatz
2019Comparison of different methodologies for selecting PELMO input parameters for groundwater modelling of plant protection products including current EU guidance (SANC0/12117/2014 - final, 2014)
Klein, Michael
Bericht
2019A comparison of log Kow (n‑octanol-water partition coefficient) values for non‑ionic, anionic, cationic and amphoteric surfactants determined using predictions and experimental methods
Hodges, Geoff; Eadsforth, Charles; Bossuyt, Bart; Bouvy, Alain; Enrici, Marie‑Helene; Geurts, Marc; Kotthoff, Matthias; Michie, Eleanor; Miller, Dennis; Müller, Josef; Oetter, Gunter; Roberts, Jayne; Schowanek, Diederik; Sun, Ping; Venzmer, Joachim
Zeitschriftenaufsatz
2019Comparison of microbial and transient expression (tobacco plants and plant-cell packs) for the production and purification of the anticancer mistletoe lectin viscumin
Gengenbach, B.B.; Keil, L.L.; Opdensteinen, P.; Müschen, C.R.; Melmer, G.; Lentzen, H.; Bührmann, J.; Buyel, J.F.
Zeitschriftenaufsatz
2019Comparison of the environmental properties of parasiticides and harmonisation of the basis for environmental assessment at the EU level
Römbke, Jörg; Duis, Karen; Egeler, Philipp; Gilberg, Daniel; Schuh, Christine; Herrchen, Monika; Hennecke, Dieter; Hölzle, Ludwig E.; Heilmann-Thudium, Brigitte; Wohde, Manuel; Wagner, Julia; Düring, Rolf-Alexander
Bericht
2019Complete genome sequence of the corallopyronin a-producing myxobacterium corallococcus coralloides B035
Bouhired, S.; Rupp, O.; Blom, J.; Schäberle, T.F.; Schiefer, A.; Kehraus, S.; Pfarr, K.; Goesmann, A.; Hoerauf, A.; König, G.
Zeitschriftenaufsatz
2019The complete mitochondrial genome of the hymenopteran hunting robber fly Dasypogon diadema
Drukewitz, S.H.; Jauss, R.-T.; Bokelmann, L.; Reumont, B.M. von
Zeitschriftenaufsatz
2019Computational functional genomics-based reduction of disease-related gene sets to their key components
Lippmann, C.; Ultsch, A.; Lötsch, J.
Zeitschriftenaufsatz
2019Computer-Aided Selective Optimization of Side Activities of Talinolol
Hiesinger, K.; Kramer, J.S.; Achenbach, J.; Moser, D.; Weber, J.; Wittmann, S.K.; Morisseau, C.; Angioni, C.; Geisslinger, G.; Kahnt, A.S.; Kaiser, A.; Proschak, A.; Steinhilber, D.; Pogoryelov, D.; Wagner, K.; Hammock, B.D.; Proschak, E.
Zeitschriftenaufsatz
2019Computer-Assisted Discovery and Structural Optimization of a Novel Retinoid X Receptor Agonist Chemotype
Heitel, P.; Gellrich, L.; Kalinowsky, L.; Heering, J.; Kaiser, A.; Ohrndorf, J.; Proschak, E.; Merk, D.
Zeitschriftenaufsatz
2019The conspicuous postmetamorphic coloration of fire salamanders, but not their toxicity, is affected by larval background albedo
Sanchez, E.; Pröhl, H.; Lüddecke, T.; Schulz, S.; Steinfartz, S.; Vences, M.
Zeitschriftenaufsatz
2019Conversion of chitin to defined chitosan oligomers: Current status and future prospects
Schmitz, C.; Auza, L.G.; Koberidze, D.; Rasche, S.; Fischer, R.; Bortesi, L.
Zeitschriftenaufsatz
2019Correction to: Progress on bringing together raptor collections in Europe for contaminant research and monitoring in relation to chemicals regulation (Environmental Science and Pollution Research, (2019), 26, 20, (20132-20136), 10.1007/s11356-019-05340-6)
Movalli, P.; Duke, G.; Ramello, G.; Dekker, R.; Vrezec, A.; Shore, R.F.; García-Fernández, A.; Wernham, C.; Krone, O.; Alygizakis, N.; Badry, A.; Barbagli, F.; Biesmeijer, K.; Boano, G.; Bond, A.L.; Choresh, Y.; Christensen, J.B.; Cincinelli, A.; Danielsson, S.; Dias, A.; Dietz, R.; Eens, M.; Espín, S.; Eulaers, I.; Frahnert, S.; Fuiz, T.I.; Gkotsis, G.; Glowacka, N.; Gómez-Ramírez, P.; Grotti, M.; Guiraud, M.; Hosner, P.; Johansson, U.; Jaspers, V.L.B.; Kamminga, P.; Koschorreck, J.; Knopf, B.; Kubin, E.; Brutto, S.L.; Lourenco, R.; Martellini, T.; Martínez-López, E.; Mateo, R.; Nika, M.-C.; Nikolopoulou, V.; Osborn, D.; Pauwels, O.; Pavia, M.; Pereira, M.G.; Rüdel, H.; Sanchez-Virosta, P.; Slobodnik, J.; Sonne, C.; Thomaidis, N.; Töpfer, T.; Treu, G.; Väinölä, R.; Valkama, J.; Mije, S. van der; Vangeluwe, D.; Warren, B.H.; Woog, F.
Zeitschriftenaufsatz
2019The Correlation Between DsRed mRNA Levels and Transient DsRed Protein Expression in Plants Depends on Leaf Age and the 5′ Untranslated Region
Jansing, J.; Buyel, J.F.
Zeitschriftenaufsatz
2019Critical analysis of the commercial potential of plants for the production of recombinant proteins
Schillberg, S.; Raven, N.; Spiegel, H.; Rasche, S.; Buntru, M.
Zeitschriftenaufsatz
2019Curvature induction and membrane remodeling by FAM134B reticulon homology domain assist selective ER-phagy
Bhaskara, R.M.; Grumati, P.; Garcia-Pardo, J.; Kalayil, S.; Covarrubias-Pinto, A.; Chen, W.; Kudryashev, M.; Dikic, I.; Hummer, G.
Zeitschriftenaufsatz
2019CXCL16/CXCR6-mediated adhesion of human peripheral blood mononuclear cells to inflamed endothelium
Linke, B.; Meyer Dos Santos, S.; Picard-Willems, B.; Keese, M.; Harder, S.; Geisslinger, G.; Scholich, K.
Zeitschriftenaufsatz
2019Cytokine-induced endogenous production of prostaglandin D2 is essential for human group 2 innate lymphoid cell activation
Maric, J.; Ravindran, A.; Mazzurana, L.; Acker, A. van; Rao, A.; Kokkinou, E.; Ekoff, M.; Thomas, D.; Fauland, A.; Nilsson, G.; Wheelock, C.E.; Dahlen, S.-E.; Ferreiros, N.; Geisslinger, G.; Friberg, D.; Heinemann, A.; Konya, V.; Mjösberg, J.
Zeitschriftenaufsatz
2019A Data Science-Based Analysis Points at Distinct Patterns of Lipid Mediator Plasma Concentrations in Patients with Dementia
Gurke, R.; Etyemez, S.; Prvulovic, D.; Thomas, D.; Fleck, S.C.; Reif, A.; Geisslinger, G.; Lötsch, J.
Zeitschriftenaufsatz
2019Degradation and transformation of fluoroquinolones by microorganisms with special emphasis on ciprofloxacin
Rusch, M.; Spielmeyer, A.; Zorn, H.; Hamscher, G.
Zeitschriftenaufsatz
2019Description of a new Moridilla species from North Sulawesi, Indonesia (Mollusca: Nudibranchia: Aeolidioidea) - based on MicroCT, histological and molecular analyses
Schillo, D.; Wipfler, B.; Undap, N.; Papu, A.; Böhringer, N.; Eisenbarth, J.-H.; Kaligis, F.; Bara, R.; Schäberle, T.F.; König, G.M.; Wägele, H.
Zeitschriftenaufsatz
2019Description of defensive postures of the natterjack toad epidalea calamita (Laurenti 1768) and notes on the release of toxic secretions
Stawikowski, R.; Lüddecke, T.
Zeitschriftenaufsatz
2019Determination of endocannabinoids and endocannabinoid-like substances in human K3EDTA plasma - LC-MS/MS method validation and pre-analytical characteristics
Gurke, R.; Thomas, D.; Schreiber, Y.; Schäfer, S.M.G.; Fleck, S.C.; Geisslinger, G.; Ferreiros, N.
Zeitschriftenaufsatz
2019Deubiquitinase USP10 regulates Notch signaling in the endothelium
Lim, R.; Sugino, T.; Nolte, H.; Andrade, J.; Zimmermann, B.; Shi, C.; Doddaballapur, A.; Ong, Y.T.; Wilhelm, K.; Fasse, J.W.D.; Ernst, A.; Kaulich, M.; Husnjak, K.; Boettger, T.; Guenther, S.; Braun, T.; Krüger, M.; Benedito, R.; Dikic, I.; Potente, M.
Zeitschriftenaufsatz
2019Development of a metabolic pathway transfer and genomic integration system for the syngas-fermenting bacterium Clostridium ljungdahlii
Philipps, G.; Vries, S. de; Jennewein, S.
Zeitschriftenaufsatz
2019Development study of pectin/Surelease® solid microparticles for the delivery of L-alanyl-L-glutamine dipeptide
Nova, M.V.; Nothnagel, L.; Thurn, M.; Travassos, P.B.; Herculano, L.S.; Bittencourt, P.R.S.; Novello, C.R.; Bazotte, R.B.; Wacker, M.G.; Bruschi, M.L.
Zeitschriftenaufsatz
2019A dialysis-based in vitro drug release assay to study dynamics of the drug-protein transfer of temoporfin liposomes
Wallenwein, C.M.; Villa Nova, M.; Janas, C.; Jablonka, L.; Gao, G.F.; Thurn, M.; Albrecht, V.; Wiehe, A.; Wacker, M.G.
Zeitschriftenaufsatz
2019Discovery of the First in Vivo Active Inhibitors of the Soluble Epoxide Hydrolase Phosphatase Domain
Kramer, JS.; Woltersdorf, S.; Duflot, T.; Hiesinger, K.; Lillich, FF.; Knoll, F.; Wittmann, SK.; Klingler, FM.; Brunst, S.; Chaikuad, A.; Morisseau, C.; Hammock, BD.; Buccellati, C.; Sala, A.; Rovati, GE.; Leuillier, M.; Fraineau, S.; Rondeaux, J.; Hernandez-Olmos, V.; Heering, J.; Merk, D.; Pogoryelov, D.; Steinhilber, D.; Knapp, S.; Bellien, J.; Proschak, E.
Zeitschriftenaufsatz
2019Discovery pipelines for marine resources: An ocean of opportunity for biotechnology?
Smith, D.; Buddie, A.G.; Goss, R.J.M.; Overmann, J.; Lepleux, C.; Brönstrup, M.; Kloareg, B.; Meiners, T.; Brennecke, P.; Ianora, A.; Bouget, F.-Y.; Gribbon, P.; Pina, M.
Zeitschriftenaufsatz
2019Downstream processing of Cry4AaCter-induced inclusion bodies containing insect-derived antimicrobial peptides produced in Escherichia coli
Hoffmann, D.; Eckhardt, D.; Gerlach, D.; Vilcinskas, A.; Czermak, P.
Zeitschriftenaufsatz
2019Driving next-generation autophagy researchers towards translation (DRIVE), an international PhD training program on autophagy
Kraft, C.; Boya, P.; Codogno, P.; Elazar, Z.; Eskelinen, E.-L.; Farres, J.; Kirkin, V.; Jungbluth, H.; Martinez, A.; Pless, O.; Primard, C.; Proikas-Cezanne, T.; Simonsen, A.; Reggiori, F.
Zeitschriftenaufsatz
2019The Drosophila melanogaster antimicrobial peptides Mtk-1 and Mtk-2 are active against the malarial parasite Plasmodium falciparum
Tonk, M.; Pierrot, C.; Cabezas-Cruz, A.; Rahnamaeian, M.; Khalife, J.; Vilcinskas, A.
Zeitschriftenaufsatz
2019Effects of continuous theta-burst stimulation of the primary motor and secondary somatosensory areas on the central processing and the perception of trigeminal nociceptive input in healthy volunteers
Annak, O.; Heidegger, T.; Walter, C.; Deichmann, R.; Nöth, U.; Hansen-Goos, O.; Ziemann, U.; Lötsch, J.
Zeitschriftenaufsatz
2019The effects of gibberellic acid on allium cepa root tip meristematic cells
Tütünoğlu, B.; Aksoy, Ö.; Özbek, R.; Uçkan, F.
Zeitschriftenaufsatz
2019Efficacy Of Etanercept Over A Period Of 12 Months In The Routine Treatment Of Patients With RA, AxSpA, PsA Or Pso: Final Results Of A German Non-Interventional, Prospective, Multi-Center Study (Adequate)
Feist, E.; Baraliakos, X.; Behrens, F.; Thaci, D.; Klopsch, T.; Plenske, A.; Blindzellner, L.K.; Meng, T.; Löschmann, P.A.
Abstract
2019Elimination of HER3-expressing breast cancer cells using aptamer-siRNA chimeras
Nachreiner, I.; Hussain, A.F.; Wullner, U.; Machuy, N.; Meyer, T.F.; Fischer, R.; Gattenlöhner, S.; Meinhold-Heerlein, I.; Barth, S.; Tur, M.K.
Zeitschriftenaufsatz
2019Elucidation of chemical modifier reactivity towards peptides and proteins and the analysis of specific fragmentation by matrix‐assisted laser desorption/ionization collision‐induced dissociation tandem mass spectrometry
Rühl, M.; Kühn, B.; Roos, J.; Maier, T.J.; Steinhilber, D.; Karas, M.
Zeitschriftenaufsatz, Konferenzbeitrag
2019Endokrin wirksame Umweltchemikalien in Lebensmitteln
Schäfers, C.; Licht, O.; Bitsch, A.
Zeitschriftenaufsatz
2019Enhancement of Benzothiazoles as Pteridine Reductase-1 Inhibitors for the Treatment of Trypanosomatidic Infections
Linciano, P.; Pozzi, C.; Iacono, L. dello; Pisa, F. di; Landi, G.; Bonucci, A.; Gul, S.; Kuzikov, M.; Ellinger, B.; Witt, G.; Santarem, N.; Baptista, C.; Franco, C.; Moraes, C.B.; Müller, W.; Wittig, U.; Luciani, R.; Sesenna, A.; Quotadamo, A.; Ferrari, S.; Pöhner, I.; Cordeiro-da-Silva, A.; Mangani, S.; Costantino, L.; Costi, M.P.
Zeitschriftenaufsatz
2019The enzymes OSC1 and CYP716A263 produce a high variety of triterpenoids in the latex of Taraxacum koksaghyz
Pütter, K.M.; Deenen, N. van; Müller, B.; Fuchs, L.; Vorwerk, K.; Unland, K.; Bröker, J.N.; Scherer, E.; Huber, C.; Eisenreich, W.; Prüfer, D.; Schulze Gronover, C.
Zeitschriftenaufsatz
2019Epigenetic Mechanisms Are Involved in Sex-Specific Trans-Generational Immune Priming in the Lepidopteran Model Host Manduca sexta
Gegner, J.; Baudach, A.; Mukherjee, K.; Halitschke, R.; Vogel, H.; Vilcinska, A.
Zeitschriftenaufsatz
2019Epigenetic mechanisms mediate the experimental evolution of resistance against parasitic fungi in the greater wax moth Galleria mellonella
Mukherjee, K.; Dubovskiy, I.; Grizanova, E.; Lehmann, R.; Vilcinskas, A.
Zeitschriftenaufsatz
2019ER-Mitochondria Communication in Cells of the Innate Immune System
Namgaladze, D.; Khodzhaeva, V.; Brüne, B.
Zeitschriftenaufsatz
2019EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology
Brennecke, P.; Rasina, D.; Aubi, O.; Herzog, K.; Landskron, J.; Cautain, B.; Vicente, F.; Quintana, J.; Mestres, J.; Stechmann, B.; Ellinger, B.; Brea, J.; Kolanowski, J.L.; Pilarski, R.; Orzaez, M.; Pineda-Lucena, A.; Laraia, L.; Nami, F.; Zielenkiewicz, P.; Paruch, K.; Hansen, E.; Kries, J.P. von; Neuenschwander, M.; Specker, E.; Bartunek, P.; Simova, S.; Lesnikowski, Z.; Krauss, S.; Lehtio, L.; Bilitewski, U.; Bronstrup, M.; Tasken, K.; Jirgensons, A.; Lickert, H.; Clausen, M.H.; Andersen, J.H.; Vicent, M.J.; Genilloud, O.; Martinez, A.; Nazare, M.; Fecke, W.; Gribbon, P.
Zeitschriftenaufsatz
2019Evaluation of microbial shifts caused by a silver nanomaterial: Comparison of four test systems
Hund-Rinke, Kerstin; Hümmler, Anna; Schlinkert, Ruben; Wege, Franziska; Broll, Gabriele
Zeitschriftenaufsatz
2019Evolutionary ecology of parasitic fungi and their host insects
Vilcinskas, A.
Zeitschriftenaufsatz
2019Factors determining microbial colonization of liquid nitrogen storage tanks used for archiving biological samples
Bajerski, F.; Bürger, A.; Glasmacher, B.; Keller, E.R.J.; Müller, K.; Mühldorfer, K.; Nagel, M.; Rüdel, H.; Müller, T.; Schenkel, J.; Overmann, J.
Zeitschriftenaufsatz
2019Fast Multiplex real time PCR method for sex-identification of medaka (Oryzias latipes) by non-invasive sampling
Diaz, C.; Böhle, G.; Wege, F.; Teigeler, M.; Eilebrecht, E.
Zeitschriftenaufsatz
2019Fate of a perfluoroalkyl acid mixture in an agricultural soil studied in lysimeters
McLachlan, M.S.; Felizeter, S.; Klein, M.; Kotthoff, M.; Voogt, P. de
Zeitschriftenaufsatz
2019First evidence of anticoagulant rodenticides in fish and suspended particulate matter: Spatial and temporal distribution in German freshwater aquatic systems
Kotthoff, Matthias; Rüdel, Heinz; Jürling, Heinrich; Severin, Kevin; Hennecke, Stephan; Friesen, Anton; Koschorreck, Jan
Zeitschriftenaufsatz
2019First Survey of Heterobranch Sea Slugs (Mollusca, Gastropoda) from the Island Sangihe, North Sulawesi, Indonesia
Undap, N.; Papu, A.; Schillo, D.; Ijong, F.G.; Kaligis, F.; Lepar, M.; Hertzer, C.; Böhringer, N.; König, G.M.; Schäberle, T.F.; Wägele, H.
Zeitschriftenaufsatz
2019Flow cytometry-based FRET identifies binding intensities in PPARγ1 protein-protein interactions in living cells
Trümper, V.; Knethen, A. von; Preuß, A.; Ermilov, E.; Hackbarth, S.; Kuchler, L.; Gunne, S.; Schäfer, A.; Bornhütter, T.; Vereb, G.; Ujlaky-Nagy, L.; Brüne, B.; Röder, B.; Schindler, M.; Parnham, M.J.; Knape, T.
Zeitschriftenaufsatz
2019Forced degradation studies to identify critical process parameters for the purification of infectious measles virus
Loewe, D.; Häussler, J.; Grein, T.A.; Dieken, H.; Weidner, T.; Salzig, D.; Czermak, P.
Zeitschriftenaufsatz
2019Förderung der Wiederbepflanzung von Windbruchflächen im Sauerland
Drabkin, Dimitri; Weinfurtner, Karlheinz
Aufsatz in Buch
2019Fraunhofer-Institut für Molekularbiologie und Angewandte Oekologie. Jahresbericht 2018
 
Jahresbericht
2019Generation of transgenic cell suspension cultures of the model legume Medicago truncatula: A rapid method for Agrobacterium mediated gene transfer
Santos, Rita B.; Pires, Ana Sofia; Hoorn, Renier A.L. van der; Schiermeyer, Andreas; Abranches, Rita
Zeitschriftenaufsatz
2019Genome analysis of the marine bacterium Labrenzia sp. strain 011, a potential protective agent of mollusks
Moghaddam, J.A.; Dávila-Céspedes, A.; Alanjary, M.; Blom, J.; König, G.M.; Schäberle, T.F.
Zeitschriftenaufsatz
2019Genome Editing in Agriculture: Technical and Practical Considerations
Jansing, Julia; Schiermeyer, Andreas; Schillberg, Stefan; Fischer, Rainer; Bortesi, Luisa
Zeitschriftenaufsatz
2019Genomic targeting by recombinase‐mediated cassette exchange in the spotted wing drosophila, Drosophila suzukii
Schetelig, M.F.; Yan, Y.; Zhao, Y.; Handler, A.M.
Zeitschriftenaufsatz
2019GLP-1 levels predict cardiovascular risk in patients with acute myocardial infarction
Kahles, F.; Ruckbeil, M.V.; Mertens, R.W.; Foldenauer, A.C.; Arrivas, M.C.; Moellmann, J.; Lebherz, C.; Biener, M.; Giannitsis, E.; Katus, H.A.; Marx, N.; Lehrke, M.
Abstract
2019GPER1 influences cellular homeostasis and cytostatic drug resistance via influencing long chain ceramide synthesis in breast cancer cells
Wegner, M.-S.; Gruber, L.; Schömel, N.; Trautmann, S.; Brachtendorf, S.; Fuhrmann, D.; Schreiber, Y.; Olesch, C.; Brüne, B.; Geisslinger, G.; Grösch, S.
Zeitschriftenaufsatz
2019High Treatment Satisfaction Of Therapy With Ustekinumab In Patients With Active Psoriatic Arthritis Due To Early And Long-Term Treatment Response And High Tolerability – Results Of The Non-Interventional Study Sustain
Wendler, J.; Wagener, P.; Hamann, F.; Damann, N.; Movshovich, E.; Behrens, F.
Abstract
2019High-Throughput Fluorescence Polarization Assay to Identify Ligands Using Purified G Protein-Coupled Receptor
Heine, P.; Witt, G.; Gilardi, A.; Gribbon, P.; Kummer, L.; Plückthun, A.
Zeitschriftenaufsatz
2019Histone Deacetylation Inhibitors as Therapy Concept in Sepsis. Review
Knethen, A. von; Brüne, B.
Zeitschriftenaufsatz
2019Hitze stabilisiert Malariaimpfstoffkandidaten in komplexen Proteinextrakten
Buyel, J.F.
Zeitschriftenaufsatz
2019Identification and characterization of approved drugs and drug-like compounds as covalent Escherichia coli ClpP inhibitors
Sassetti, E.; Durante Cruz, C.; Tammela, P.; Winterhalter, M.; Augustyns, K.; Gribbon, P.; Windshügel, B.
Zeitschriftenaufsatz
2019Identification of novel agonists by high-throughput screening and molecular modelling of human constitutive androstane receptor isoform 3
Keminer, O.; Windshügel, B.; Essmann, F.; Lee, S.M.L.; Schiergens, T.S.; Schwab, M.; Burk, O.
Zeitschriftenaufsatz
2019IL-38 Ameliorates Skin Inflammation and Limits IL-17 Production from γδ T Cells
Han, Y.; Mora, J.; Huard, A.; Silva, P. da; Wiechmann, S.; Putyrski, M.; Schuster, C.; Elwakeel, E.; Lang, G.; Scholz, A.; Scholz, T.; Schmid, T.; Bruin, N. de; Billuart, P.; Sala, C.; Burkhardt, H.; Parnham, M.J.; Ernst, A.; Brüne, B.; Weigert, A.
Zeitschriftenaufsatz
2019Imatinib stimulates prostaglandin E2 and attenuates cytokine release via EP4 receptor activation
Bärnthaler, T.; Jandl, K.; Sill, H.; Uhl, B.; Schreiber, Y.; Grill, M.; Thomas, D.; Schicho, R.; Marsche, G.; Frank, S.; Heinemann, A.; Schuligoi, R.
Zeitschriftenaufsatz
2019Immunogenicity assay development and validation for biological therapy as exemplified by ustekinumab
Mojtahed Poor, S.; Ulshöfer, T.; Gabriel, L.A.; Henke, M.; Köhm, M.; Behrens, F.; Geisslinger, G.; Parnham, M.J.; Burkhardt, H.; Schiffmann, S.
Zeitschriftenaufsatz
2019The immunome of soy bean allergy: Comprehensive identification and characterization of epitopes
Kern, Karolin; Havenith, Heide; Delaroque, Nicolas; Rautenberger, Paul; Lehmann, Jörg; Fischer, Markus; Spiegel, Holger; Schillberg, Stefan; Ehrentreich-Förster, Eva; Aurich, Stefanie; Treudler, Regina; Szardenings, Michael
Zeitschriftenaufsatz
2019Implantable wireless biometric animal telemetry system: a powerful tool to improve translational sepsis research
Knape, T.; Wilken-Schmitz, A.; Schneider, A.K.; Arne, O.; Schmidt, M.; Götze, L.; Hofmann, M.C.J.; Bruin, N.M.W.J. de; Gerdes, C.; Glenschek-Sieberth, M.; Schmidt, M.V.; Remie, R.; Brill, B.; Parnham, M.J.; Knethen, A. von
Abstract
2019Influence of methionine residue position on oxidative stability of glucose oxidase from Aspergillus niger
Kovacevic, G.; Ostafe, R.; Fischer, R.; Prodanovic, R.
Zeitschriftenaufsatz
2019Inhibition of histone acetylation and deacetylation enzymes affects longevity, development, and fecundity in the pea aphid (Acyrthosiphon pisum)
Kirfel, P.; Skaljac, M.; Grotmann, J.; Kessel, T.; Seip, M.; Michaelis, K.; Vilcinskas, A.
Zeitschriftenaufsatz
2019Inhibition of the protein kinase IKKepsilon attenuates neuropathic pain in mice
Möser, C.V.; Möller, M.; Fleck, S.C.; Thomas, D.; Geisslinger, G.; Niederberger, E.
Zeitschriftenaufsatz
2019Insektenbiotechnologie: Insekten als Ressource
Vilcinskas, Andreas
Aufsatz in Buch
2019The Integration of Algal Carbon Concentration Mechanism Components into Tobacco Chloroplasts Increases Photosynthetic Efficiency and Biomass
Nölke, G.; Barsoum, M.; Houdelet, M.; Arcalis, E.; Kreuzaler, F.; Fischer, R.; Schillberg, S.
Zeitschriftenaufsatz
2019Iron as a Central Player and Promising Target in Cancer Progression. Review
Jung, M.; Mertens, C.; Tomat, E.; Brüne, B.
Zeitschriftenaufsatz
2019Isolation and Identification of Alkaloids from Poisons of Fire Salamanders (Salamandra salamandra)
Knepper, J.; Lüddecke, T.; Preißler, K.; Vences, M.; Schulz, S.
Zeitschriftenaufsatz
2019Konzept zur Implementierung der neuen Umweltqualitätsnormen für prioritäre Stoffe in Fischen (Richtlinie 2013/39/EU). Abschlussbericht
Radermacher, Georg; Fliedner, Annette; Rüdel, Heinz
Bericht
2019Laccase-induced HBT-grafting to milled beech wood reduces unspecific protein adsorption
Jestel, T.; Roth, S.; Heesel, D.; Kress, A.; Fischer, R.; Spiess, A.C.
Zeitschriftenaufsatz
2019Levels, accumulation patterns and retrospective trends of perfluoroalkyl acids (PFAAs) in terrestrial ecosystems over the last three decades
Falk, Sandy; Stahl, Thorsten; Fliedner, Annette; Rüdel, Heinz; Tarricone, Kathrin; Brunn, Hubertus; Koschorreck, Jan
Zeitschriftenaufsatz
2019The Lipid Status in Patients with Ulcerative Colitis: Sphingolipids are Disease-Dependent Regulated
Bazarganipour, S.; Hausmann, J.; Oertel, S.; El-Hindi, K.; Brachtendorf, S.; Blumenstein, I.; Kubesch, A.; Sprinzl, K.; Birod, K.; Hahnefeld, L.; Trautmann, S.; Thomas, D.; Herrmann, E.; Geisslinger, G.; Schiffmann, S.; Grösch, S.
Zeitschriftenaufsatz
2019Long-term outdoor lysimeter study with cerium dioxide nanomaterial
Hoppe, M.; Schlich, K.; Wielinski, J.; Köser, J.; Rückamp, D.; Kaegi, R.; Hund-Rinke, K.
Zeitschriftenaufsatz
2019Loss of function mutation of the Rapid Alkalinization Factor (RALF1)-like peptide in the dandelion Taraxacum koksaghyz entails a high-biomass taproot phenotype
Wieghaus, A.; Prüfer, D.; Schulze Gronover, C.
Zeitschriftenaufsatz
2019Loxapine for treatment of patients with refractory, chemotherapy-induced neuropathic pain: A prematurely terminated pilot study showing efficacy but limited tolerability
Schmiedl, S.; Peters, D.; Schmalz, O.; Mielke, A.; Rossmanith, T.; Diop, S.; Piefke, M.; Thürmann, P.; Schmidtko, A.
Zeitschriftenaufsatz
2019Machine Learning in Human Olfactory Research
Lötsch, J.; Kringel, D.; Hummel, T.
Zeitschriftenaufsatz
2019A machine-learned analysis suggests non-redundant diagnostic information in olfactory subtests
Lötsch, J.; Hummel, T.
Zeitschriftenaufsatz
2019Macrophage HIF‐2α regulates tumor-suppressive Spint1 in the tumor microenvironment
Susen, R.M.; Bauer, R.; Olesch, C.; Fuhrmann, D.C.; Fink, A.F.; Dehne, N.; Jain, A.; Ebersberger, I.; Schmid, T.; Brüne, B.
Zeitschriftenaufsatz
2019Macrophage S1PR1 Signaling Alters Angiogenesis and Lymphangiogenesis During Skin Inflammation
Syed, S.N.; Raue, R.; Weigert, A.; Knethen, A. von; Brüne, B.
Zeitschriftenaufsatz
2019Maintaining hepatic PD-L1 expression improves sepsis survival in a murine polymicrobial sepsis model by tolerizing CTL
Knethen, A. von; Schäfer, A.; Kuchler, L.; Knape, T.; Christen, U.; Hintermann, E.; Fisslthaler, B.; Schröder, K.; Brandes, R.P.; Genz, B.; Abshagen, K.; Pützer, B.M.; Sha, L.K.; Weigert, A.; Syed, S.N.; Schulz, M.; Shah, A.M.; Ernst, A.; Putyrski, M.; Finkelmeier, F.; Pesic, M.; Greten, F.; Hoghardt, M.; Kempf, V.A.J.; Gunne, S.; Parnham, M.J.; Brüne, B.
Abstract
2019Molecular Targeting Therapy against EGFR Family in Breast Cancer. Progress and Future Potentials
Maennling, A.E.; Tur, M.K.; Niebert, M.; Klockenbring, Torsten; Zeppernick, F.; Gattenlöhner, S.; Meinhold-Heerlein, I.; Hussain, A.F.
Zeitschriftenaufsatz
2019Monoclonal Antibody AP3 Binds Galactomannan Antigens Displayed by the Pathogens Aspergillus flavus, A. fumigatus, and A. parasiticus
Schubert, M.; Xue, S.; Ebel, F.; Vaggelas, A.; Krylov, V.B.; Nifantiev, N.E.; Chudobova, I.; Schillberg, S.; Nölke, G.
Zeitschriftenaufsatz
2019More yellow more toxic? Sex rather than alkaloid content is correlated with yellow coloration in the fire salamander
Preißler, K.; Gippner, S.; Lüddecke, T.; Krause, E.T.; Schulz, S.; Vences, M.; Steinfartz, S.
Zeitschriftenaufsatz
2019The nanoGRAVUR framework to group (nano)materials for their occupational, consumer, environmental risks based on a harmonized set of material properties, applied to 34 case studies
Wohlleben, W.; Hellack, B.; Nickel, C.; Herrchen, M.; Hund-Rinke, K.; Kettler, K.; Riebeling, C.; Haase, A.; Funk, B.; Kühnel, D.; Göhler, D.; Stintz, M.; Schumacher, C.; Wiemann, M.; Keller, J.; Landsiedel, R.; Brossell, D.; Pitzko, S.; Kuhlbusch, T.A.J.
Zeitschriftenaufsatz
2019Nanomedicines - Tiny particles and big challenges
Marques, M.R.C.; Choo, Q.; Ashtikar, M.; Rocha, T.C.; Bremer-Hoffmann, S.; Wacker, M.G.
Zeitschriftenaufsatz
2019The need for comparative data in spondyloarthritis
Choy, E.; Baraliakos, X.; Behrens, F.; D'Angelo, S.; Vlam, K. de; Kirkham, B.W.; Ostergaard, M.; Schett, G.A.; Rissler, M.; Chaouche-Teyara, K.; Perella, C.
Zeitschriftenaufsatz
2019A new lipoxygenase from the agaric fungus Agrocybe aegerita: Biochemical characterization and kinetic properties
Karrer, D.; Rühl, M.
Zeitschriftenaufsatz
2019A new sesquiterpenoid aminoquinone from an Indonesian marine sponge
Balansa, W.; Mettal, U.; Wuisan, Z.G.; Plubrukarn, A.; Ijong, F.G.; Liu, Y.; Schäberle, T.F.
Zeitschriftenaufsatz
2019New terpenoids from the fermentation broth of the edible mushroom Cyclocybe aegerita
Surup, F.; Hennicke, F.; Sella, N.; Stroot, M.; Bernecker, S.; Pfütze, S.; Stadler, M.; Rühl, M.
Zeitschriftenaufsatz
2019Non-invasive imaging and modeling of liver regeneration after partial hepatectomy
Zafarnia, S.; Mrugalla, A.; Rix, A.; Doleschel, D.; Gremse, F.; Wolf, S.D.; Buyel, J.F.; Albrecht, U.; Bode, J.G.; Kiessling, F.; Lederle, W.
Zeitschriftenaufsatz
2019Novel Approaches to Persistent Pain Therapy
Sisignano, M.; Parnham, M.J.; Geisslinger, G.
Zeitschriftenaufsatz
2019Nutzung der Erfahrungen und Ergebnisse des Biotamonitorings der Umweltprobenbank für die Umsetzung des WRRL-Fischmonitorings
Fliedner, Annette; Rüdel, Heinz; Koschorreck, Jan
Zeitschriftenaufsatz
2019Omega-3 and -6 fatty acid plasma levels are not associated with liver cirrhosis-associated systemic inflammation
Schwarzkopf, K.M.; Queck, A.; Thomas, D.; Angioni, C.; Cai, C.; Freygang, Y.; Rüschenbaum, S.; Geisslinger, G.; Zeuzem, S.; Welsch, C.; Lange, C.M.
Zeitschriftenaufsatz
2019Organismen als Produzenten: Produktion von Wertstoffen mithilfe von Mikroorganismen, Algen und Pflanzenzellen
Rasche, Stefan; Schillberg, Stefan; Derwenskus, Felix; Schmid-Staiger, Ulrike; Schließmann, Ursula
Aufsatz in Buch
2019Oxidosqualene cyclase knock-down in latex of taraxacum koksaghyz reduces triterpenes in roots and separated natural rubber
Deenen, N. van; Unland, K.; Prüfer, D.; Schulze Gronover, C.
Zeitschriftenaufsatz
2019Passive equilibrium sampling of hydrophobic organic compounds in homogenised fish tissues of low lipid content
Rojo-Nieto, Elisa; Muz, Melis; Koschorreck, Jan; Rüdel, Heinz; Jahnke, Annika
Zeitschriftenaufsatz
2019Pathogens associated with invasive or introduced insects threaten the health and diversity of native species
Vilcinskas, A.
Zeitschriftenaufsatz
2019Pflanzenschutzmittel im Grundwasser: Besteht ein Umweltrisiko?
Schäfers, Christoph; Klein, Michael
Konferenzbeitrag
2019Phenotypic Plasticity of Fibroblasts during Mammary Carcinoma Development
Elwakeel, E.; Brüggemann, M.; Fink, A.F.; Schulz, M.H.; Schmid, T.; Savai, R.; Brüne, B.; Zarnack, K.; Weigert, A.
Zeitschriftenaufsatz
2019Phylogeny-Guided Selection of Priority Groups for Venom Bioprospecting
Lüddecke, T.; Vilcinskas, A.; Lemke, S.
Zeitschriftenaufsatz
2019Plant cell packs: A scalable platform for recombinant protein production and metabolic engineering
Rademacher, T.; Sack, M.; Blessing, D.; Fischer, R.; Holland, T.; Buyel, J.
Zeitschriftenaufsatz
2019Plant Molecular Farming - Integration and Exploitation of Side Streams to Achieve Sustainable Biomanufacturing
Buyel, J.F.
Zeitschriftenaufsatz
2019Potential biomarkers for persistent and neuropathic pain therapy
Sisignano, M.; Lötsch, J.; Parnham, M.J.; Geisslinger, G.
Zeitschriftenaufsatz
2019Practical advice for selecting or determining trophic magnification factors for application under the European Union water framework directive
Kidd, K.A.; Burkhard, Lawrence P.; Babut, M.; Borgå, Katrine; Muir, Derek C.G.; Perceval, Olivier; Ruedel, Heinz; Woodburn, Kent; Embry, Michelle R.
Zeitschriftenaufsatz
2019The precursor hypothesis of sponge kleptocnidism: Development of nematocysts in Haliclona cnidata sp. nov. (porifera, demospongiae, haplosclerida)
Schellenberg, J.; Reichert, J.; Hardt, M.; Schmidtberg, H.; Kämpfer, P.; Glaeser, S.P.; Schubert, P.; Wilke, T.
Zeitschriftenaufsatz
2019Predictive PBPK modeling as a tool in the formulation of the drug candidate TMP-001
Nothnagel, L.; Jung, F.; Rossmanith, T.; Thurn, M.; Ashtikar, M.; Geisslinger, G.; Parnham, M.J.; Wacker, M.G.
Zeitschriftenaufsatz
2019Probability Of Achieving Low Disease Activity Or Remission In Subjects With Active Psoriatic Arthritis Treated With Apremilast
Mease, P.J.; Behrens, F.; Gladman, D.D.; Kavanaugh, A.; Brunori, M.; Teng, L.C.; Guerette, B.; Queiro, R.; Ogdie, A.
Abstract
2019Process intensification for an insect antimicrobial peptide elastin-like polypeptide fusion produced in redox-engineered Escherichia coli
Joachim, M.; Maguire, N.; Schäfer, J.; Gerlach, D.; Czermak, P.
Zeitschriftenaufsatz
2019Processing Induced Degradation Routes of Prochloraz in Rapeseed Oil
Göckener, Bernd; Kotthoff, Matthias; Kling, Hans-Willi; Bücking, Mark
Zeitschriftenaufsatz
2019Profiling antimicrobial peptides from the medical maggot Lucilia sericata as potential antibiotics for MDR Gram-negative bacteria
Hirsch, R.; Wiesner, J.; Marker, A.; Pfeifer, Y.; Bauer, A.; Hammann, P.E.; Vilcinskas, A.
Zeitschriftenaufsatz
2019Progress on bringing together raptor collections in Europe for contaminant research and monitoring in relation to chemicals regulation
Movalli, Paola; Duke, Guy; Ramello, Gloria; Dekker, René; Vrezec, Al; Shore, Richard F.; García-Fernández, Antonio; Wernham, Chris; Krone, Oliver; Alygizakis, Nikiforos; Badry, Alexander; Barbagli, Fausto; Biesmeijer, Koos; Boano, Giovanni; Bond, Alexander L.; Choresh, Yael; Bolding Christensen, Jan; Cincinelli, Alessandra; Danielsson, Sara; Dias, Andreia; Dietz, Rune; Eens, Marcel; Espín, Silvia; Eulaers, Igor; Frahnert, Sylke; Fuiz, Tibor I.; Gkotsis, Georgios; Glowacka, Natalia; Gómez-Ramírez, Pilar; Grotti, Marco; Guiraud, Michel; Hosner, Peter; Johansson, Ulf; Jaspers, Veerle L.B.; Kamminga, Pepijn; Koschorreck, Jan; Knopf, Burkhard; Kubin, Eero; LoBrutto, Sabrina; Lourenco, Rui; Martellini, Tania; Martínez-López, Emma; Mateo, Rafael; Nika, Maria-Christina; Nikolopoulou, Varvara; Osborn, Dan; Pauwels, Olivier; Pavia, Marco; Pereira, M. Glória; Rüdel, Heinz; Sanchez-Virosta, Pablo; Slobodnik, Jaroslav; Sonne, Christian; Thomaidis, Nikolaos; Töpfer, Till; Treu, Gabriele; Väinölä, Risto; Valkama,
Zeitschriftenaufsatz
2019Protection of the groundwater against loads of plant protection products: Validation of the new EU-simulation model FO-CUS PELMO 4 for a reliable prediction of the leaching potential of PPP into groundwater
Klein, Michael; Thomas, Kai; Trapp, Matthias; Guerniche, Djamal
Bericht
2019Protection of the groundwater against loads of plant protection products: Validation of the new EU-simulation model FO-CUS PELMO 4 for a reliable prediction of the leaching potential of PPP into groundwater
Klein, Michael; Thomas, Kai; Trapp, Matthias; Guerniche, Djamal
Bericht
2019Proteomic Analysis of the Venom from the Ruby Ant Myrmica rubra and the Isolation of a Novel Insecticidal Decapeptide
Heep, J.; Klaus, A.; Kessel, T.; Seip, M.; Vilcinskas, A.; Skaljac, M.
Zeitschriftenaufsatz
2019Psoriatic Arthritis Impact Of Disease Questionnaire Scores Are Correlated With Disease Activity, As Measured By cDAPSA, In Patients With Psoriatic Arthritis
Orbai, A.M.; Krueger, K.; Behrens, F.; Kiltz, U.; Guerette, B.; Mellars, L.; Brunori, M.; Wollenhaupt, J.
Abstract
2019Rating the risks of anticoagulant rodenticides in the aquatic environment: A review
Regnery, Julia; Friesen, Anton; Geduhn, Anke; Göckener, Bernd; Kotthoff, Matthias; Parrhysius, Pia; Petersohn, Eleonora; Reifferscheid, Georg; Schmolz, Erik; Schulz, Robert S.; Schwarzbauer, Jan; Brinke, Marvin
Zeitschriftenaufsatz
2019Ready-to-Use Stocks of Agrobacterium tumefaciens can Simplify Process Development for the Production of Recombinant Proteins by Transient Expression in Plants
Spiegel, H.; Boes, A.; Perales Morales, C.; Rademacher, T.; Buyel, J.F.
Zeitschriftenaufsatz
2019Recent findings of halogenated flame retardants (HFR) in the German and Polar environment
Dreyer, Annekatrin; Neugebauer, Frank; Lohmann, Nina; Rüdel, Heinz; Teubner, Diana; Grotti, Marco; Rauert, Caren; Koschorreck, Jan
Zeitschriftenaufsatz
2019Redox regulation of PPAR gamma in polarized macrophages
Trümper, V.; Wittig, I.; Heidler, J.; Brüne, B.; Knethen, A. von
Abstract
2019Reduced neuropathic pain behavior in mice lacking the cyclic nucleotide-gated channel subunit CNGB1
Kallenborn-Gerhardt, W.; Lu, R.; Petersen, J.J.; Metzner, K.; Kuth, M.S.; Heine, S.; Drees, O.; Paul, M.; Becirovic, E.; Kennel, L.; Flauaus, C.; Gross, T.; Wack, G.; Hohmann, S.W.; Turco, D. del; Biel, M.; Geisslinger, G.; Michalakis, S.; Schmidtko, A.
Abstract
2019A response regulator of the OmpR family is part of the regulatory network controlling the oxidative stress response of Rhodobacter sphaeroides
Zhao, Z.; Peng, T.; Oh, J.-I.; Glaeser, J.; Weber, L.; Li, Q.; Klug, G.
Zeitschriftenaufsatz
2019RNAi targeting of rootworm Troponin I transcripts confers root protection in maize
Fishilevich, E.; Bowling, A.J.; Frey, M.L.F.; Wang, P.-H.; Lo, W.; Rangasamy, M.; Worden, S.E.; Pence, H.E.; Gandra, P.; Whitlock, S.L.; Schulenberg, G.; Knorr, E.; Tenbusch, L.; Lutz, J.R.; Novak, S.; Hamm, R.L.; Schnelle, K.D.; Vilcinskas, A.; Narva, K.E.
Zeitschriftenaufsatz
2019Role of ceramide synthase 2 in G-CSF signaling and G-CSF-R translocation into detergent-resistant membranes
Kurz, J.; Barthelmes, J.; Blum, L.; Ulshöfer, T.; Wegner, M.-S.; Ferreiros, N.; Roser, L.; Geisslinger, G.; Grösch, S.; Schiffmann, S.
Zeitschriftenaufsatz
2019Russell-like bodies in plant seeds share common features with prolamin bodies and occur upon recombinant protein production
Arcalis, E.; Ibl, V.; Hilscher, J.; Rademacher, T.; Avesani, L.; Morandini, F.; Bortesi, L.; Pezzotti, M.; Vitale, A.; Pum, D.; Meyer, T. de; Depicker, A.; Stoger, E.
Zeitschriftenaufsatz
2019SAR Studies and Biological Characterization of a Chromen-4-one Derivative as an Anti- Trypanosoma brucei Agent
Borsari, C.; Santarem, N.; Macedo, S.; Jiménez-Antón, M.D.; Torrado, J.J.; Olías-Molero, A.I.; Corral, M.J.; Tait, A.; Ferrari, S.; Costantino, L.; Luciani, R.; Ponterini, G.; Gul, S.; Kuzikov, M.; Ellinger, B.; Behrens, B.; Reinshagen, J.; Alunda, J.M.; Cordeiro-Da-Silva, A.; Costi, M.P.
Zeitschriftenaufsatz
2019Selective Inactivation of Cancer Drugs by SAMHD1 Provides a Molecular Rationale for Therapeutic Stratification in AML
Schneider, C.; Oellerich, T.; Knecht, K.M.; Thomas, D.; Buzovetsky, O.; Schliemann, C.; Bohnenberger, H.; Angenendt, L.; Hartmann, W.; Wardelmann, E.; Scheich, S.; Comoglio, F.; Wilke, A.; Ströbel, P.; Serve, H.; Geisslinger, G.; Keppler, O.T.; Xiong, Y.; Cinatl, J.
Abstract
2019Selective inactivation of hypomethylating agents by SAMHD1 provides a rationale for therapeutic stratification in AML
Oellerich, T.; Schneider, C.; Thomas, D.; Knecht, K.M.; Buzovetsky, O.; Kaderali, L.; Schliemann, C.; Bohnenberger, H.; Angenendt, L.; Hartmann, W.; Wardelmann, E.; Rothenburger, T.; Mohr, S.; Scheich, S.; Comoglio, F.; Wilke, A.; Ströbel, P.; Serve, H.; Michaelis, M.; Ferreiros, N.; Geisslinger, G.; Xiong, Y.; Keppler, O.T.; Cinatl, J.
Zeitschriftenaufsatz
2019Sensitive and rapid detection of cholera toxin subunit B using magnetic frequency mixing detection
Achtsnicht, S.; Neuendorf, C.; Faßbender, T.; Nölke, G.; Offenhäusser, A.; Krause, H.-J.; Schröper, F.
Zeitschriftenaufsatz
2019Shooting three inflammatory targets with a single bullet: Novel multi-targeting anti-inflammatory glitazones
Elzahhar, P.A.; Alaaeddine, R.; Ibrahim, T.M.; Nassra, R.; Ismail, A.; Chua, B.S.K.; Frkic, R.L.; Bruning, J.B.; Wallner, N.; Knape, T.; Knethen, A. von; Labib, H.; El-Yazbi, A.F.; Belal, A.S.F.
Zeitschriftenaufsatz
2019The significance of comparative genomics in modern evolutionary venomics
Drukewitz, S.H.; Reumont, B.M. von
Zeitschriftenaufsatz
2019Silencing of the DNA methyltransferase 1 associated protein 1 (DMAP1) gene in the invasive ladybird Harmonia axyridis implies a role of the DNA methyltransferase 1-DMAP1 complex in female fecundity
Gegner, J.; Gegner, T.; Vogel, H.; Vilcinskas, A.
Zeitschriftenaufsatz
2019Simplified tracking of a soy allergen in processed food using a monoclonal antibody-based sandwich ELISA targeting the soybean 2S albumin gly m 8
Ueberham, Elke; Spiegel, Holger; Havenith, Heide; Rautenberger, Paul; Lidzba, Norbert; Schillberg, Stefan; Lehmann, Jörg
Zeitschriftenaufsatz
2019Sphingosine kinase 2 is a negative regulator of inflammatory macrophage activation
Weigert, A.; Knethen, A. von; Thomas, D.; Faria, I.; Namgaladze, D.; Zezina, E.; Fuhrmann, D.; Petcherski, A.; Meyer zu Heringdorf, D.; Radeke, H.H.; Brüne, B.
Zeitschriftenaufsatz
2019Sphingosine-1-Phosphate and Macrophage Biology - How the Sphinx Tames the Big Eater
Weigert, A.; Olesch, C.; Brüne, B.
Zeitschriftenaufsatz
2019Stability of Biorelevant Media Under Various Storage Conditions
Klumpp, L.; Nagasekar, K.; McCullough, O.; Seybert, A.; Ashtikar, M.; Dressman, J.
Zeitschriftenaufsatz
2019Stimulating brain recovery after stroke using theranostic albumin nanocarriers loaded with nerve growth factor in combination therapy
Feczkó, T.; Piiper, A.; Ansar, S.; Blixt, F.W.; Ashtikar, M.; Schiffmann, S.; Ulshöfer, T.; Parnham, M.J.; Harel, Y.; Israel, L.L.; Lellouche, J.-P.; Wacker, M.G.
Zeitschriftenaufsatz
2019Strategies to Interfere with Tumor Metabolism through the Interplay of Innate and Adaptive Immunity
Mora, J.; Mertens, C.; Meier, J.K.; Fuhrmann, D.C.; Brüne, B.; Jung, M.
Zeitschriftenaufsatz
2019Structural insights into ligand-binding pocket formation in Nurr1 by molecular dynamics simulations
Windshügel, B.
Zeitschriftenaufsatz
2019Structural Insights into the Development of Cycloguanil Derivatives as Trypanosoma brucei Pteridine-Reductase-1 Inhibitors
Landi, G.; Linciano, P.; Borsari, C.; Bertolacini, C.P.; Moraes, C.B.; Cordeiro-da-Silva, A.; Gul, S.; Witt, G.; Kuzikov, M.; Costi, M.P.; Pozzi, C.; Mangani, S.
Zeitschriftenaufsatz
2019Structure optimization of a new class of PPARγ antagonists
Hernandez-Olmos, V.; Knape, T.; Heering, J.; Knethen, A. von; Kilu, W.; Kaiser, A.; Wurglics, M.; Helmstadter, M.; Merk, D.; Schubert-Zsilavecz, M.; Parnham, M.J.; Steinhilber, D.; Proschak, E.
Zeitschriftenaufsatz
2019Surface Acoustic Wave-Based Microfluidic Coagulation Device for Monitoring Anticoagulant Therapy
Harder, S.; Meyer dos Santos, S.; Krozer, V.; Moll, J.
Zeitschriftenaufsatz
2019Symbiont‐mediated chemical defense in the invasive ladybird Harmonia axyridis
Schmidtberg, H.; Shukla, S.P.; Halitschke, R.; Vogel, H.; Vilcinskas, A.
Zeitschriftenaufsatz
2019Synthesis, Biological Evaluation and Structure: Activity Relationships of Diflapolin Analogues as Dual sEH/FLAP Inhibitors
Vieider, L.; Romp, E.; Temml, V.; Fischer, J.; Kretzer, C.; Schoenthaler, M.; Taha, A.; Hernandez-Olmos, V.; Sturm, S.; Schuster, D.; Werz, O.; Garscha, U.; Matuszczak, B.
Zeitschriftenaufsatz
2019Tarantula phylogenomics: A robust phylogeny of deep theraphosid clades inferred from transcriptome data sheds light on the prickly issue of urticating setae evolution
Foley, S.; Lüddecke, T.; Cheng, D.-Q.; Krehenwinkel, H.; Künzel, S.; Longhorn, S.J.; Wendt, I.; Wirth, V. von; Tänzler, R.; Vences, M.; Piel, W.H.
Zeitschriftenaufsatz
2019Targeted insertion of large DNA sequences by homology-directed repair or non-homologous end joining in engineered tobacco BY-2 cells using designed zinc finger nucleases
Schiermeyer, Andreas; Schneider, Katja; Kirchhoff, Janina; Schmelter, Thomas; Koch, Natalie; Ke, Jiang; Herwartz, Denise; Blue, Ryan; Marri, Pradeep; Samuel, Pon; Corbin, David R.; Webb, Steven R.; Gonzalez, Delkin O.; Folkerts, Otto; Fischer, Rainer; Schinkel, Helga; Ainley, W. Michael; Schillberg, Stefan
Zeitschriftenaufsatz
2019Targeted lipidomics reveal derangement of ceramides in major depression and bipolar disorder
Brunkhorst-Kanaan, N.; Klatt-Schreiner, K.; Hackel, J.; Schröter, K.; Trautmann, S.; Hahnefeld, L.; Wicker, S.; Reif, A.; Thomas, D.; Geisslinger, G.; Kittel-Schneider, S.; Tegeder, I.
Zeitschriftenaufsatz
2019Testing effects of pesticides on macroinvertebrate communities in outdoor stream mesocosms using carbaryl as example test item
Beuter, Liesa‑Kristin; Dören, László; Hommen, Udo; Kotthoff, Matthias; Schäfers, Christoph; Ebke, Klaus-Peter
Zeitschriftenaufsatz
2019The therapeutic potential of the insect metalloproteinase inhibitor against infections caused by Pseudomonas aeruginosa
Eisenhardt, M.; Schlupp, P.; Höfer, F.; Schmidts, T.; Hoffmann, D.; Czermak, P.; Pöppel, A.-K.; Vilcinskas, A.; Runkel, F.
Zeitschriftenaufsatz
2019Thromboxane-Induced α-CGRP Release from Peripheral Neurons Is an Essential Positive Feedback Loop in Capsaicin-Induced Neurogenic Inflammation
Tarighi, N.; Menger, D.; Pierre, S.; Kornstädt, L.; Thomas, D.; Ferreiros, N.; Nüsing, R.M.; Geisslinger, G.; Scholich, K.
Zeitschriftenaufsatz
2019A tiered high-throughput screening approach for evaluation of estrogen and androgen receptor modulation by environmentally relevant bisphenol A substitutes
Keminer, Oliver; Teigeler, Matthias; Kohler, Manfred; Wenzel, Andrea; Arning, Jürgen; Kaßner, Franziska; Windshügel, Björn; Eilebrecht, Elke
Zeitschriftenaufsatz
2019Tissue Cytokine IL-33 Modulates the Cytotoxic CD8 T Lymphocyte Activity During Nutrient Deprivation by Regulation of Lineage-Specific Differentiation Programs
Dreis, C.; Ottenlinger, F.M.; Putyrski, M.; Ernst, A.; Huhn, M.; Schmidt, K.G.; Pfeilschifter, J.M.; Radeke, H.H.
Zeitschriftenaufsatz
2019Tolerizing CTL by Sustained Hepatic PD-L1 Expression Provides a New Therapy Approach in Mouse Sepsis
Knethen, A. von; Schäfer, A.; Kuchler, L.; Knape, T.; Christen, U.; Hintermann, E.; Fißlthaler, B.; Schröder, K.; Brandes, R.P.; Genz, B.; Abshagen, K.; Pützer, B.M.; Sha, L.K.; Weigert, A.; Syed, S.N.; Schulz, M.; Shah, A.M.; Ernst, A.; Putyrski, M.; Finkelmeier, F.; Pesic, M.; Greten, F.; Hogardt, M.; Kempf, V.A.J.; Gunne, S.; Parnham, M.J.; Brüne, B.
Zeitschriftenaufsatz
2019Toxins from scratch? Diverse, multimodal gene origins in the predatory robber fly Dasypogon diadema indicate a dynamic venom evolution in dipteran insects
Drukewitz, S.H.; Bokelmann, L.; Undheim, E.A.B.; Reumont, B.M. von
Zeitschriftenaufsatz
2019Transcriptome sequencing of a keystone aquatic herbivore yields insights on the temperature-dependent metabolism of essential lipids
Windisch, Heidrun S.; Fink, Patrick
Zeitschriftenaufsatz
2019Transmission of a protease-secreting bacterial symbiont among pea aphids via host plants
Skaljac, M.; Vogel, H.; Wielsch, N.; Mihajlovic, S.; Vilcinskas, A.
Zeitschriftenaufsatz
2019Tribolium castaneum as a whole‐animal screening system for the detection and characterization of neuroprotective substances
Brandt, A.; Joop, G.; Vilcinskas, A.
Zeitschriftenaufsatz
2019TRPA1 Sensitization Produces Hyperalgesia to Heat but not to Cold Stimuli in Human Volunteers
Weyer-Menkhoff, I.; Lötsch, J.
Zeitschriftenaufsatz
2019Tunicate-associated bacteria show a great potential for the discovery of antimicrobial compounds
Ayuningrum, D.; Liu, Y.; Riyanti; Sibero, M.T.; Kristiana, R.; Asagabaldan, M.A.; Wuisan, Z.G.; Trianto, A.; Radjasa, O.K.; Sabdono, A.; Schaberle, T.F.
Zeitschriftenaufsatz
2019Tuning Nuclear Receptor Selectivity of Wy14,643 towards Selective Retinoid X Receptor Modulation
Pollinger, J.; Gellrich, L.; Schierle, S.; Kilu, W.; Schmidt, J.; Kalinowsky, L.; Ohrndorf, J.; Kaiser, A.; Heering, J.; Proschak, E.; Merk, D.
Zeitschriftenaufsatz
2019Two-step production of neofructo-oligosaccharides using immobilized heterologous aspergillus terreus 1f-fructosyltransferase expressed in Kluyveromyces lactis and native Xanthophyllomyces dendrorhous G6-fructosyltransferase
Burghardt, J.P.; Baas, M.; Gerlach, D.; Czermak, P.
Zeitschriftenaufsatz
2019Uncovering mechanisms of rubber biosynthesis in Taraxacum koksaghyz - role of cis-prenyltransferase-like 1 protein
Niephaus, E.; Müller, B.; Deenen, N. van; Lassowskat, I.; Bonin, M.; Finkemeier, I.; Prüfer, D.; Schulze Gronover, C.
Zeitschriftenaufsatz
2019A validated LC-MS/MS method for the determination of homocysteic acid in biological samples
Gurke, R.; Schmidt, D.; Thomas, D.; Fleck, S.C.; Geisslinger, G.; Ferreiros, N.
Zeitschriftenaufsatz
2019Verhalten nanomaterialhaltiger Schlacken und Aschen aus Müllverbrennung und Klärschlammverbrennung
Oischinger, Jürgen; Meisterjahn, Boris
Vortrag
2019Versorgungssituation von Patienten mit ankylosierender Spondylitis und Psoriasisarthritis in Deutschland
Braun, J.; Schwarting, A.; Hammel, L.; Legeler, C.; Wimmer, P.; Färber, L.; Behrens, F.
Zeitschriftenaufsatz
2019Zafirlukast Is a Dual Modulator of Human Soluble Epoxide Hydrolase and Peroxisome Proliferator-Activated Receptor γ
Göbel, T.; Diehl, O.; Heering, J.; Merk, D.; Angioni, C.; Wittmann, S.K.; Buscato, E. la; Kottke, R.; Weizel, L.; Schader, T.; Maier, T.J.; Geisslinger, G.; Schubert-Zsilavecz, M.; Steinhilber, D.; Proschak, E.; Kahnt, A.S.
Zeitschriftenaufsatz
201820-HETE promotes glucose-stimulated insulin secretion in an autocrine manner through FFAR1
Tunaru, S.; Bonnavion, R.; Brandenburger, I.; Preussner, J.; Thomas, D.; Scholich, K.; Offermanns, S.
Zeitschriftenaufsatz
20188-Methoxypsoralen Plus Ultraviolet A Reduces the Psoriatic Response to Imiquimod in a Murine Model
Shirsath, N.; Wagner, K.; Tangermann, S.; Schlederer, M.; Ringel, C.; Kenner, L.; Brüne, B.; Wolf, P.
Zeitschriftenaufsatz
2018Abatacept used in combination with non-methotrexate disease-modifying antirheumatic drugs
Alten, R.; Burkhardt, H.; Feist, E.; Krüger, K.; Rech, J.; Rubbert-Roth, A.; Voll, R.E.; Elbez, Y.; Rauch, C.
Zeitschriftenaufsatz
2018Achieving adequate protection and suitable food safety indicators
Pucher, J.; Schlechtriem, Christian
Aufsatz in Buch
2018Activation of Adenylyl Cyclase Causes Stimulation of Adenosine Receptors
Pleli, T.; Mondorf, A.; Ferreiros, N.; Thomas, D.; Dvorak, K.; Biondi, R.M.; Heringdorf, D.M.; Zeuzem, S.; Geisslinger, G.; Zimmermann, H.; Waidmann, O.; Piiper, A.
Zeitschriftenaufsatz
2018Advances and Challenges in Drug Design of PPARδ Ligands
Maltarollo, V.G.; Kronenberger, T.; Windshugel, B.; Wrenger, C.; Goulart Trossini, G.H.; Honorio, K.M.
Zeitschriftenaufsatz
2018Advances in the development of procedures to establish the toxicity of non-extractable residues (NER) in soil. LRI-ECO25
Harmsen, Joop; Hennecke, Dieter; Hund-Rinke, Kerstin; Lahr, Joost; Deneer, John
Bericht
2018AICAR inhibits NFκB DNA binding independently of AMPK to attenuate LPS-triggered inflammatory responses in human macrophages
Kirchner, J.; Brüne, B.; Namgaladze, D.
Zeitschriftenaufsatz
2018Analysis and Optimization of Ecotoxicological Models under Uncertainty
Klein, Judith
: Schultz, Rüdiger; Escudero, Laureano F.; Schäfers, Christoph
Dissertation
2018Anti-inflammatory nitro-fatty acids suppress tumor growth by triggering mitochondrial dysfunction and activation of the intrinsic apoptotic pathway in colorectal cancer cells
Kühn, B.; Brat, C.; Fettel, J.; Hellmuth, N.; Maucher, I.V.; Bulut, I.; Hock, K.J.; Grimmer, J.; Manolikakes, G.; Rühl, M.; Kühn, A.; Zacharowski, K.; Matrone, C.; Urbschat, A.; Roos, J.; Steinhilber, D.; Maier, T.J.
Zeitschriftenaufsatz
2018Antiplasmodial activity of tick defensins in a mouse model of malaria
Couto, J.; Tonk, M.; Ferrolho, J.; Antunes, S.; Vilcinskas, A.; Fuente, J. de la; Domingos, A.; Cabezas-Cruz, A.
Zeitschriftenaufsatz
2018Apoptotic Cancer Cells Suppress 5-Lipoxygenase in Tumor-Associated Macrophages
Ringleb, J.; Strack, E.; Angioni, C.; Geisslinger, G.; Steinhilber, D.; Weigert, A.; Brüne, B.
Zeitschriftenaufsatz
2018Artificial neural network-assisted spectrophotometric method for monitoring fructo-oligosaccharides production
Erdős, B.; Grachten, M.; Czermak, P.; Kovács, Z.
Zeitschriftenaufsatz
2018Aryl thiosemicarbazones for the treatment of trypanosomatidic infections
Linciano, P.; Moraes, C.B.; Alcantara, L.M.; Franco, C.H.; Pascoalino, B.; Freitas-Junior, L.H.; Macedo, S.; Santarem, N.; Cordeiro-da-Silva, A.; Gul, S.; Witt, G.; Kuzikov, M.; Ellinger, B.; Ferrari, S.; Luciani, R.; Quotadamo, A.; Costantino, L.; Costi, M.P.
Zeitschriftenaufsatz
2018Aspergillus-specific antibodies: Targets and applications
Schubert, M.; Spiegel, H.; Schillberg, S.; Nölke, G.
Zeitschriftenaufsatz
2018Assessment of seafood contamination under the marine strategy framework directive: Contributions of the German environmental specimen bank
Fliedner, Annette; Rüdel, Heinz; Knopf, Burkhard; Lohmann, Nina; Paulus, Martin; Jud, Michael; Pirntke, Ulrike; Koschorreck, Jan
Zeitschriftenaufsatz
2018Astrocytic ATX fuels synaptic phospholipid signaling involved in psychiatric disorders
Thalman, C.; Horta, G.; Qiao, L.; Endle, H.; Tegeder, I.; Cheng, H.; Laube, G.; Sigrudsson, T.; Hauser, M.J.; Tenzer, S.; Distler, U.; Aoki, J.; Morris, A.J.; Geisslinger, G.; Röper, J.; Kirischuk, S.; Luhmann, H.J.; Radyushkin, K.; Nitsch, R.; Vogt, J.
Zeitschriftenaufsatz
2018Astrocytic ATX fuels synaptic phospholipid signaling involved in psychiatric disorders
Thalman, C.; Horta, G.; Qiao, L.; Endle, H.; Tegeder, I.; Cheng, H.; Laube, G.; Sigrudsson, T.; Hauser, M.J.; Tenzer, S.; Distler, U.; Aoki, J.; Morris, A.J.; Geisslinger, G.; Röper, J.; Kirischuk, S.; Luhmann, H.J.; Radyushkin, K.; Nitsch, R.; Vogt, J.
Zeitschriftenaufsatz
2018Biomarker und Bildgebung zur Diagnose und Stratifizierung der rheumatoiden Arthritis und Spondylarthritis im BMBF-Verbund ArthroMark
Häupl, T.; Skapenko, A.; Hoppe, B.; Skriner, K.; Burkhardt, H.; Poddubnyy, D.; Ohrndorf, S.; Sewerin, P.; Mansmann, U.; Stuhlmüller, B.; Schulze-Koops, H.; Burmester, G.-R.
Zeitschriftenaufsatz
2018Biomarker und Bildgebung zur Diagnose und Stratifizierung der rheumatoiden Arthritis und Spondylarthritis im BMBF-Verbund ArthroMark
Häupl, T.; Skapenko, A.; Hoppe, B.; Skriner, K.; Burkhardt, H.; Poddubnyy, D.; Ohrndorf, S.; Sewerin, P.; Mansmann, U.; Stuhlmüller, B.; Schulze-Koops, H.; Burmester, G.-R.
Zeitschriftenaufsatz
2018Bioreactor-based production of glycoproteins in plant cell suspension cultures
Holland, T.; Buyel, J.F.
Aufsatz in Buch
2018Biota monitoring under the Water Framework Directive: On tissue choice and fish species selection
Fliedner, Annette; Rüdel, Heinz; Lohmann, Nina; Buchmeier, Georgia; Koschorreck, Jan
Zeitschriftenaufsatz
2018Boosting Anti-Inflammatory Potency of Zafirlukast by Designed Polypharmacology
Schierle, S.; Flauaus, C.; Heitel, P.; Willems, S.; Schmidt, J.; Kaiser, A.; Weizel, L.; Goebel, T.; Kahnt, A.S.; Geisslinger, G.; Steinhilber, D.; Wurglics, M.; Rovati, G.E.; Schmidtko, A.; Proschak, E.; Merk, D.
Zeitschriftenaufsatz
2018Bovine embryo elongation is altered due to maternal fatty acid supplementation
Giller, K.; Drews, B.; Berard, J.; Kienberger, H.; Schmicke, M.; Frank, J.; Spanier, B.; Daniel, H.; Geisslinger, G.; Ulbrich, S.E.
Zeitschriftenaufsatz
2018C5aR activation in the absence of C5a
Syed, S.N.; Rau, E.; Ziegelmann, M.; Sogkas, G.; Brüne, B.; Schmidt, R.E.
Zeitschriftenaufsatz
2018Cationic polyacrylamide copolymers (PAMs): Environmental half life determination in sludge‑treated soil
Hennecke, Dieter; Bauer, Angela; Herrchen, Monika; Wischerhoff, Erik; Gores, Friedhelm
Zeitschriftenaufsatz
2018Cell adhesion-induced transient interaction of ADAM15 with poly(A) binding protein at the cell membrane colocalizes with mRNA translation
Böhm, B.B.; Fehrl, Y.; Janczi, T.; Schneider, N.; Burkhardt, H.
Zeitschriftenaufsatz
2018Cell-free protein synthesis system
Buntru, Matthias; Schillberg, Stefan; Vogel, Simon
Patent
2018Challenges in the Development of a Thiol-Based Broad-Spectrum Inhibitor for Metallo-β-Lactamases
Büttner, D.; Kramer, J.S.; Klingler, F.-M.; Wittmann, S.K.; Hartmann, M.R.; Kurz, C.G.; Kohnhäuser, D.; Weizel, L.; Brüggerhoff, A.; Frank, D.; Steinhilber, D.; Wichelhaus, T.A.; Pogoryelov, D.; Proschak, E.
Zeitschriftenaufsatz
2018Characterization of interleukin-6 monoclonal antibodies for future applications
Chouman, K.
Dissertation
2018Characterization of new anti-IL-6 antibodies revealed high potency candidates for intracellular cytokine detection and specific targeting of IL-6 receptor binding sites
Chouman, Karinna; Korioth-Schmitz, Birgit; Sack, Markus; Engelbert Schmitz, Jörn; Tuan Pham, Anh; Fischer, Rainer; Barth, Stefan; Klockenbring, Torsten; Fendel, Rolf
Zeitschriftenaufsatz
2018Charakterisierung und zelluläre Lokalisation der humanen 5-Lipoxygenase und deren Isoformen 5-LO∆13, 5-LO∆4 und 5-LOp12
Ball, A.-K.
Dissertation
2018Chemosensitivity of human colon cancer cells is influenced by a p53-dependent enhancement of ceramide synthase 5 and induction of autophagy
Brachtendorf, S.; Wanger, R.A.; Birod, K.; Thomas, D.; Trautmann, S.; Wegner, M.-S.; Fuhrmann, D.C.; Brüne, B.; Geisslinger, G.; Grösch, S.
Zeitschriftenaufsatz
2018Combined Proteomic and In Silico Target Identification Reveal a Role for 5-Lipoxygenase in Developmental Signaling Pathways
Brand, S.; Roy, S.; Schröder, P.; Rathmer, B.; Roos, J.; Kapoor, S.; Patil, S.; Pommerenke, C.; Maier, T.; Janning, P.; Eberth, S.; Steinhilber, D.; Schade, D.; Schneider, G.; Kumar, K.; Ziegler, S.; Waldmann, H.
Zeitschriftenaufsatz
2018Comparative analysis of the transcriptome responses of zebrafish embryos after exposure to low concentrations of cadmium, cobalt and copper
Sonnack, Laura; Klawonn, Thorsten; Kriehuber, Ralf; Hollert, Henner; Schäfers, Christoph; Fenske, Martina
Zeitschriftenaufsatz
2018Comparative estrogenicity of endogenous, environmental and dietary estrogens in pregnant women I
Fleck, S.C.; Twaddle, N.C.; Churchwell, M.I.; Doerge, D.R.; Pande, P.; Teeguarden, J.G.
Zeitschriftenaufsatz
2018A comparison of two biorelevant in vitro drug release methods for nanotherapeutics based on advanced physiologically-based pharmacokinetic modelling
Jung, F.; Nothnagel, L.; Gao, F.; Thurn, M.; Vogel, V.; Wacker, M.G.
Zeitschriftenaufsatz
2018Computational functional genomics-based approaches in analgesic drug discovery and repurposing
Lippmann, C.; Kringel, D.; Ultsch, A.; Lötsch, J.
Zeitschriftenaufsatz
2018A coupled fluorescence-based assay for the detection of protein arginine N-methyltransferase 6 (PRMT6) enzymatic activity
Kramer, J.; Désor, V.; Brunst, S.; Wittmann, S.K.; Lausen, J.; Heering, J.; Proschak, A.; Proschak, E.
Zeitschriftenaufsatz
2018Current evidence of cannabinoid-based analgesia obtained in preclinical and human experimental settings
Lötsch, J.; Weyer-Menkhoff, I.; Tegeder, I.
Zeitschriftenaufsatz
2018Current status and perspectives of the molecular farming landscape
Spiegel, H.; Stöger, E.; Twyman, R.M.; Buyel, J.F.
Aufsatz in Buch
2018Decreasing δ13C and δ15N values in four coastal species at different trophic levels indicate a fundamental food-web shift in the southern North and Baltic Seas between 1988 and 2016
Corman, Anna-Marie; Schwemmer, Philipp; Mercker, Moritz; Asmus, Harald; Rüdel, Heinz; Klein, Roland; Boner, Markus; Hofem, Sabine; Koschorreck, Jan; Garthe, Stefan
Zeitschriftenaufsatz
2018Development of a Focused Library of Triazole‐Linked Privileged‐Structure‐Based Conjugates Leading to the Discovery of Novel Phenotypic Hits against Protozoan Parasitic Infections
Uliassi, E.; Piazzi, L.; Belluti, F.; Mazzanti, A.; Kaiser, M.; Brun, R.; Moraes, C.B.; Freitas-Junior, L.H.; Gul, S.; Kuzikov, M.; Ellinger, B.; Borsari, C.; Costi, M.P.; Bolognesi, M.L.
Zeitschriftenaufsatz
2018Development of an AmpliSeqTM Panel for Next-Generation Sequencing of a Set of Genetic Predictors of Persisting Pain
Kringel, D.; Kaunisto, M.A.; Lippmann, C.; Kalso, E.; Lötsch, J.
Zeitschriftenaufsatz
2018Development, current applications and future roles of biorelevant two‐stage in vitro testing in drug development
Fiolka, T.; Dressman, J.
Zeitschriftenaufsatz
2018Dielectric Spectroscopy and Optical Density Measurement for the Online Monitoring and Control of Recombinant Protein Production in Stably Transformed Drosophila melanogaster S2 Cells
Zitzmann, J.; Weidner, T.; Eichner, G.; Salzig, D.; Czermak, P.
Zeitschriftenaufsatz
2018Dietary phytol reduces clinical symptoms in experimental autoimmune encephalomyelitis (EAE) at least partially by modulating NOX2 expression
Blum, L.; Tafferner, N.; Spring, I.; Kurz, J.; deBruin, N.; Geisslinger, G.; Parnham, M.J.; Schiffmann, S.
Zeitschriftenaufsatz
2018Differentiation of human iPSCs into VSMCs and generation of VSMC-derived calcifying vascular cells
Trillhaase, A.; Haferkamp, U.; Rangnau, A.; Märtens, M.; Schmidt, B.; Trilck, M.; Seibler, P.; Aherrahrou, R.; Erdmann, J.; Aherrahrou, Z.
Zeitschriftenaufsatz
2018Dimerization quality control via ubiquitylation
Herhaus, L.; Dikic, I.
Zeitschriftenaufsatz
2018Discovery of polar spirocyclic orally bioavailable urea inhibitors of soluble epoxide hydrolase
Lukin, A.; Kramer, J.; Hartmann, M.; Weizel, L.; Hernandez-Olmos, V.; Falahati, K.; Burghardt, I.; Kalinchenkova, N.; Bagnyukova, D.; Zhurilo, N.; Rautio, J.; Forsberg, M.; Ihalainen, J.; Auriola, S.; Leppänen, J.; Konstantinov, I.; Pogoryelov, D.; Proschak, E.; Dar'in, D.; Krasavin, M.
Zeitschriftenaufsatz
2018Downregulation of BTLA on NKT Cells Promotes Tumor Immune Control in a Mouse Model of Mammary Carcinoma
Sekar, D.; Govene, L.; Del Río, M.-L.; Sirait-Fischer, E.; Fink, A.F.; Brüne, B.; Rodriguez-Barbosa, J.I.; Weigert, A.
Zeitschriftenaufsatz
2018Downstream processing of a plant-derived malaria transmission-blocking vaccine candidate
Menzel, S.; Holland, T.; Boes, A.; Spiegel, H.; Fischer, R.; Buyel, J.F.
Zeitschriftenaufsatz
2018Drug-Mediated Intracellular Donation of Nitric Oxide Potently Inhibits 5-Lipoxygenase
Roos, J.; Peters, M.; Maucher, I.V.; Kühn, B.; Fettel, J.; Hellmuth, N.; Brat, C.; Sommer, B.; Urbschat, A.; Piesche, M.; Vogel, A.; Proschak, E.; Blöcher, R.; Buscató, E.; Häfner, A.-K.; Matrone, C.; Werz, O.; Heidler, J.; Wittig, I.; Angioni, C.; Geisslinger, G.; Parnham, M.J.; Zacharowski, K.; Steinhilber, D.; Maier, T.J.
Zeitschriftenaufsatz
2018Efficacy and safety of tregalizumab in patients with rheumatoid arthritis and an inadequate response to methotrexate
Vollenhoven, R.F. van; Keystone, E.C.; Strand, V.; Pacheco-Tena, C.; Vencovský, J.; Behrens, F.; Racewicz, A.; Zipp, D.; Rharbaoui, F.; Wolter, R.; Knierim, L.; Schmeidl, R.; Zhou, X.; Aigner, S.; Dälken, B.; Wartenberg-Demand, A.
Zeitschriftenaufsatz
2018Elimination of different leukaemia subtypes using novel CD89-specific human cytolytic fusion proteins
Gresch, G.; Schenke, L.; Mladenov, R.; Zwirner, S.; Cremer, C.; Niesen, J.; Grieger, E.; Brümmendorf, T.; Jost, E.; Fischer, R.; Stockmeyer, B.; Barth, S.; Nachreiner, T.; Stein, C.
Zeitschriftenaufsatz
2018Elusive mitochondrial connection to inflammation uncovered
Stolz, A.; Dikic, I.
Zeitschriftenaufsatz
2018Empfehlung zur Einrichtung eines nationalen Observatorien-Netzes für die terrestrische Ökosystemforschung
Kögel-Knabner, Ingrid; Teutsch, Georg; Adrian, Rita; Blanckenburg, Friedhelm von; Flügge, Ulf-Ingo; Kolle, Olaf; Kleinn, Christoph; Küsel, Kirsten; Lischeid, Gunnar; Löw, Alexander; Schäfers, Christoph; Schmid, Hans Peter; Simmer, Clemens; Vereecken, Harry; Walz, Rainer
Bericht
2018Enrichment of vitamin D2 in mycelium from submerged cultures of the agaric mushroom Pleurotus sapidus
Ahlborn, J.; Calzolari, N.; Spielmeyer, A.; Avci, S.S.; Zimmer, M.; Rühl, M.
Zeitschriftenaufsatz
2018Environmental impacts by fragments released from nanoenabled products: A multiassay, multimaterial exploration by the SUN approach
Amorim, Monica J.B.; Lin, Sijie; Schlich, Karsten; Navas, Jose Maria; Brunelli, Andrea; Neubauer, Nicole; Vilsmeier, Klaus; Costa, Anna L.; Gondikas, Andreas; Xia, Tian; Galbis, Liliana; Badetti, Elena; Marcomini, Antonio; Hristozov, Danail; Kammer, Frank von der; Hund-Rinke, Kerstin; Scott-Fordsmand, Janeck J.; Nel, André; Wohlleben, Wendel
Zeitschriftenaufsatz
2018Enzyme membrane reactor system (EMRS) for the bioconversion of lignin-containing substrates by a novel heme peroxidase
Busse, N.
Dissertation
2018The European Marine Biological Research Infrastructure Cluster: An Alliance of European Research Infrastructures to Promote the Blue Bioeconomy
Piña, M.; Colas, P.; Cancio, I.; Audic, A.; Bosser, L.; Canario, A.; Gribbon, P.; Johnston, I.A.; Kervella, A.E.; Kooistra, W.H.C.F.; Merciecca, M.; Magoulas, A.; Nardello, I.; Smith, D.; Pade, N.; Robinson, D.; Schön, A.; Schultz, F.; Kloareg, B.
Aufsatz in Buch
2018Expression and purification of human phosphatase and actin regulator 1 (PHACTR1) in plant-based systems
Gengenbach, B.B.; Müschen, C.R.; Buyel, J.F.
Zeitschriftenaufsatz
2018Fishing for contaminants
Hausen, J.; Otte, J.C.; Legradi, J.; Yang, L.; Strähle, U.; Fenske, M.; Hecker, M.; Tang, S.; Hammers-Wirtz, M.; Hollert, H.; Keiter, S.H.; Ottermanns, R.
Zeitschriftenaufsatz
2018Fitness costs of infection with Serratia symbiotica are associated with greater susceptibility to insecticides in the pea aphid Acyrthosiphon pisum
Skaljac, M.; Kirfel, P.; Grotmann, J.; Vilcinskas, A.
Zeitschriftenaufsatz
2018Four chemical trends will shape the next decade's directions in perfluoroalkyl and polyfluoroalkyl substances research
Kotthoff, Matthias; Bücking, Mark
Zeitschriftenaufsatz
2018Fraunhofer-Institut für Molekularbiologie und Angewandte Oekologie. Jahresbericht 2017/2018
 
Jahresbericht
2018A freshwater mesocosm study into the effects of the neonicotinoid insecticide thiamethoxam at multiple trophic levels
Finnegan, Meaghean C.; Emburey, Simon; Hommen, Udo; Baxter, Leilan R.; Hoekstra, Paul F.; Hanson, Mark L.; Thompson, Helen; Hamer, Mick
Zeitschriftenaufsatz
2018The FT/FD-dependent initiation of flowering under long-day conditions in the day-neutral species Nicotiana tabacum originates from the facultative short-day ancestor Nicotiana tomentosiformis
Beinecke, F.A.; Grundmann, L.; Wiedmann, D.R.; Schmidt, F.J.; Caesar, A.S.; Zimmermann, M.; Lahme, M.; Twyman, R.M.; Prüfer, D.; Noll, G.A.
Zeitschriftenaufsatz
2018Functional exploration of natural networks and ecological communities
Ankenbrand, M.J.; Hohlfeld, S.C.Y.; Weber, L.; Förster, F.; Keller, A.
Zeitschriftenaufsatz
2018The G2A Receptor Controls Polarization of Macrophage by Determining Their Localization Within the Inflamed Tissue
Kern, K.; Schäfer, S.M.G; Cohnen, J.; Pierre, S.; Osthues, T.; Tarighi, N.; Hohmann, S.; Ferreiros, N.; Brüne, B.; Weigert, A.; Geisslinger, G.; Sisignano, M.; Scholich, K.
Zeitschriftenaufsatz
2018Gene silencing in Tribolium castaneum as a tool for the targeted identification of candidate RNAi targets in crop pests
Knorr, E.; Fishilevich, E.; Tenbusch, L.; Frey, M.L.F.; Rangasamy, M.; Billion, A.; Worden, S.E.; Gandra, P.; Arora, K.; Lo, W.; Schulenberg, G.; Valverde-Garcia, P.; Vilcinskas, A.; Narva, K.E.
Zeitschriftenaufsatz
2018Generation of two human isogenic iPSC lines from fetal dermal fibroblasts
Tandon, R.; Brändl, B.; Baryshnikova, N.; Landshammer, A.; Steenpaß, L.; Keminer, O.; Pless, O.; Müller, F.-J.
Zeitschriftenaufsatz
2018Generierung und Charakterisierung rekombinanter single chain Fv-Derivate für therapeutische und diagnostische Anwendungen an unterschiedlichen Leukämie Subtypen
Gresch, G.
Dissertation
2018The genome sequence of the commercially cultivated mushroom Agrocybe aegerita reveals a conserved repertoire of fruiting-related genes and a versatile suite of biopolymer-degrading enzymes
Gupta, D.K.; Rühl, M.; Mishra, B.; Kleofas, V.; Hofrichter, M.; Herzog, R.; Pecyna, M.J.; Sharma, R.; Kellner, H.; Hennicke, F.; Thines, M.
Zeitschriftenaufsatz
2018Grouping concept for metal and metal oxide nanomaterials with regard to their ecotoxicological effects on algae, daphnids and fish embryos
Hund-Rinke, K.; Schlich, Karsten; Kühnel, Dana; Hellack, Bryan; Kaminski, Heinz; Nickel, Carmen
Zeitschriftenaufsatz
2018Halogenated flame retardants in tree samples applied as bioindicators for atmospheric pollution
Dreyer, Annekatrin; Neugebauer, Frank; Rüdel, Heinz; Klein, Roland; Lohmann, Nina; Rauert, Caren; Koschorreck, Jan
Zeitschriftenaufsatz
2018Heterotypic Ubiquitin Chains: Seeing is Believing
Stolz, A.; Dikic, I.
Zeitschriftenaufsatz
2018High cell density cultivation of Δgor/ΔtrxB E. coli in a chemically defined minimal medium with an enhanced iron concentration
Joachim, M.; Schäfer, J.G.; Gerlach, D.; Czermak, P.
Zeitschriftenaufsatz
2018High titer oncolytic measles virus production process by integration of dielectric spectroscopy as online monitoring system
Grein, T.A.; Loewe, D.; Dieken, H.; Salzig, D.; Weidner, T.; Czermak, P.
Zeitschriftenaufsatz
2018High-sensitive troponin is associated with subclinical imaging biosignature of inflammatory cardiovascular involvement in systemic lupus erythematosus
Winau, L.; Baydes, R.H.; Braner, A.; Drott, U.; Burkhardt, H.; Sangle, S.; D'Cruz, D.P.; Carr-White, G.; Marber, M.; Schnoes, K.; Arendt, C.; Klingel, K.; Vogl, T.J.; Zeiher, A.M.; Nagel, E.; Puntmann, V.O.
Zeitschriftenaufsatz
2018Highly efficient genome editing by homology-directed repair using Cas9 protein in Ceratitis capitata
Aumann, R.A.; Schetelig, M.F.; Häcker, I.
Zeitschriftenaufsatz
2018How to effectively treat acute leukemia patients bearing MLL-rearrangements?
Steinhilber, D.; Marschalek, R.
Zeitschriftenaufsatz
2018How to measure release from nanosized carriers?
Nothnagel, L.; Wacker, M.G.
Zeitschriftenaufsatz
2018Human pharmacological approaches to TRP-ion-channel-based analgesic drug development
Weyer-Menkhoff, I.; Lötsch, J.
Zeitschriftenaufsatz
2018Identification and characterization of natural viruses associated with the invasive insect pest Drosophila suzukii
Carrau, T.; Hiebert, N.; Vilcinskas, A.; Lee, K.-Z.
Zeitschriftenaufsatz
2018Identification of approved drugs as potent inhibitors of pregnane X receptor activation with differential receptor interaction profiles
Burk, O.; Kuzikov, M.; Kronenberger, T.; Jeske, J.; Keminer, O.; Thasler, W.E.; Schwab, M.; Wrenger, C.; Windshügel, B.
Zeitschriftenaufsatz
2018Identification of disease-distinct complex biomarker patterns by means of unsupervised machine-learning using an interactive R toolbox (Umatrix)
Lötsch, J.; Lerch, F.; Djaldetti, R.; Tegder, I.; Ultsch, A.
Zeitschriftenaufsatz
2018Immunological larval polyphenism in the map butterfly Araschnia levana reveals the photoperiodic modulation of immunity
Baudach, A.; Lee, K.-Z.; Vogel, H.; Vilcinskas, A.
Zeitschriftenaufsatz
2018Immunomodulation by antibiotics
Blum, L.; Schiffmann, S.; Parnham, M.J.
Aufsatz in Buch
2018An in silico approach to determine challenges in the bioavailability of ciprofloxacin, a poorly soluble weak base with borderline solubility and permeability characteristics
Hansmann, S.; Miyaji, Y.; Dressman, J.
Zeitschriftenaufsatz
2018In vitro and in silico analysis of the effects of D2 receptor antagonist target binding kinetics on the cellular response to fluctuating dopamine concentrations
Witte, W.E.A. de; Versfelt, J.W.; Kuzikov, M.; Rolland, S.; Georgi, V.; Gribbon, P.; Gul, S.; Huntjens, D.; Graaf, P.H. van der; Danhof, M.; Fernández‐Montalván, A.; Witt, G.; Lange, E.C.M. de
Zeitschriftenaufsatz
2018An in vitro test system for compounds that modulate human inflammatory macrophage polarization
Shiratori, H.; Feinweber, C.; Luckhardt, S.; Wallner, N.; Geisslinger, G.; Weigert, A.; Parnham, M.J.
Zeitschriftenaufsatz
2018Inactivation kinetics of Escherichia Coli and Staphylococcus Aureus by a hydrogen peroxide based disinfectant
Grigoryan, K.; Badalyan, G.; Nersisyan, L.; Tavadyan, L.; Sargsyan, M.
Zeitschriftenaufsatz
2018The infection of Harmonia axyridis by a parasitic nematode is mediated by entomopathogenic bacteria and triggers sex-specific host immune responses
Gegner, T.; Carrau, T.; Vilcinskas, A.; Lee, K.Z.
Zeitschriftenaufsatz
2018Inhibition of 53BP1 favors homology-dependent DNA repair and increases CRISPR-Cas9 genome-editing efficiency
Canny, M.D.; Moatti, N.; Wan, L.C.K.; Fradet-Turcotte, A.; Krasner, D.; Mateos-Gomez, P.A.; Zimmermann, M.; Orthwein, A.; Juang, Y.-C.; Zhang, W.; Noordermeer, S.M.; Seclen, E.; Wilson, M.D.; Vorobyov, A.; Munro, M.; Ernst, A.; Ng, T.F.; Cho, T.; Cannon, P.M.; Sidhu, S.S.; Sicheri, F.; Durocher, D.
Zeitschriftenaufsatz
2018Insights into catalysis and function of phosphoribosyl-linked serine ubiquitination
Kalayil, S.; Bhogaraju, S.; Bonn, F.; Shin, D.; Liu, Y.; Gan, N.; Basquin, J.; Grumati, P.; Luo, Z.-Q.; Dikic, I.
Zeitschriftenaufsatz
2018Ixekizumab is efficacious when used alone or when added to conventional synthetic disease-modifying antirheumatic drugs (cDMARDs) in patients with active psoriatic arthritis and previous inadequate response or intolerance to tumour necrosis factor inhibitors
Nash, P.; Behrens, F.; Orbai, A.-M.; Rathmann, S.S.; Adams, D.H.; Benichou, O.; Deodhar, A.
Zeitschriftenaufsatz
2018Kinetics and modeling of cell growth for potential anthocyanin induction in cultures of Taraxacum officinale G.H. Weber ex Wiggers (Dandelion) in vitro
Martínez, M.E.; Poirrier, P.; Prüfer, D.; Schulze Gronover, C.; Jorquera, L.; Ferrer, P.; Díaz, K.; Chamy, R.
Zeitschriftenaufsatz
2018Knotting nets. Molecular junctions of interconnecting endocrine axes identified by application of the adverse outcome pathway (AOP) concept
Brüggemann, Maria; Licht, Oliver; Fetter, Éva; Teigeler, Matthias; Schäfers, Christoph; Eilebrecht, Elke
Zeitschriftenaufsatz
2018Laccase production and pellet morphology of Coprinopsis cinerea transformants in liquid shake flask cultures
Rühl, M.; Lange, K.; Kües, U.
Zeitschriftenaufsatz
2018The levels of peroxisomal catalase protein and activity modulate the onset of cell death in tobacco BY-2 cells via reactive oxygen species levels and autophagy
Tyutereva, Elena V.; Dobryakova, Ksenia S.; Schiermeyer, Andreas; Shishova, Maria F.; Pawlowski, Katharina; Demidchik, Vadim; Reumann, Sigrun; Voitsekhovskaja, Olga V.
Zeitschriftenaufsatz
2018A linear epitope coupled to DsRed provides an affinity ligand for the capture of monoclonal antibodies
Rühl, C.; Knödler, M.; Opdensteinen, P.; Buyel, J.F.
Zeitschriftenaufsatz
2018Long-term effects of three different silver sulfide nanomaterials, silver nitrate and bulk silver sulfide on soil microorganisms and plants
Schlich, Karsten; Hoppe, Martin; Kraas, Marco; Schubert, Jonas; Chanana, Munish; Hund-Rinke, Kerstin
Zeitschriftenaufsatz
2018Low protease content in Medicago truncatula cell cultures facilitates recombinant protein production
Santos, Rita B.; Chandrasekar, Balakumaran; Mandal, Manoj K.; Kaschani, Farnush; Kaiser, Markus; Both, Leonard; Hoorn, Renier A.L. van der; Schiermeyer, Andreas; Abranches, Rita
Zeitschriftenaufsatz
2018Machine learning in pain research
Lötsch, J.; Ultsch, A.
Zeitschriftenaufsatz
2018A machine-learned analysis of human gene polymorphisms modulating persisting pain points to major roles of neuroimmune processes
Kringel, D.; Lippmann, C.; Parnham, M.J.; Kalso, E.; Ultsch, A.; Lötsch, J.
Zeitschriftenaufsatz
2018Machine-learned analysis of quantitative sensory testing responses to noxious cold stimulation in healthy subjects
Weyer-Menkhoff, I.; Thrun, M.C.; Lötsch, J.
Zeitschriftenaufsatz
2018Machine-learned analysis of the association of next-generation sequencing-based human TRPV1 and TRPA1 genotypes with the sensitivity to heat stimuli and topically applied capsaicin
Kringel, D.; Geisslinger, G.; Resch, E.; Oertel, B.G.; Thrun, M.C.; Heinemann, S.; Lötsch, J.
Zeitschriftenaufsatz
2018Machine-learned selection of psychological questionnaire items relevant to the development of persistent pain after breast cancer surgery
Lötsch, J.; Sipilä, R.; Dimova, V.; Kalso, E.
Zeitschriftenaufsatz
2018Machine-learning based lipid mediator serum concentration patterns allow identification of multiple sclerosis patients with high accuracy
Lötsch, J.; Schiffmann, S.; Schmitz, K.; Brunkhorst, R.; Lerch, F.; Ferreiros, N.; Wicker, S.; Tegeder, I.; Geisslinger, G.; Ultsch, A.
Zeitschriftenaufsatz
2018Machine-learning-derived classifier predicts absence of persistent pain after breast cancer surgery with high accuracy
Lötsch, J.; Sipilä, R.; Tasmuth, T.; Kringel, D.; Estlander, A.-M.; Meretoja, T.; Kalso, E.; Ultsch, A.
Zeitschriftenaufsatz
2018Mannan-induced Nos2 in macrophages enhances IL-17–driven psoriatic arthritis by innate lymphocytes
Zhong, J.; Scholz, T.; Yau, A.C.Y.; Guerard, S.; Hüffmeier, U.; Burkhardt, H.; Holmdahl, R.
Zeitschriftenaufsatz
2018Manufacturing and Safety Guidelines for Manufactured Functionalized Nanomaterials in Pharmaceutics
Wacker, M.G.; Janas, C.; Ferreira, F.S.; Vieira, F.P.
Aufsatz in Buch
2018Mechanism and medical implications of mammalian autophagy
Dikic, I.; Elazar, Z.
Zeitschriftenaufsatz
2018Mechanistic Understanding of Enhanced Human Oral Bioavailability of Fenofibric Acid from Novel Lipid Carriers Using Semi- Physiologically Based Pharmacokinetic Model and Various Analytical Approaches Including Biorelevant Dissolution Testing
Fei, Y.
Dissertation
2018Metabolomic Profiles for Primary Progressive Multiple Sclerosis Stratification and Disease Course Monitoring
Stoessel, D.; Stellmann, J.-P.; Willing, A.; Behrens, B.; Rosenkranz, S.C.; Hodecker, S.C.; Stürner, K.H.; Reinhardt, S.; Fleischer, S.; Deuschle, C.; Maetzler, W.; Berg, D.; Heesen, C.; Walther, D.; Schauer, N.; Friese, M.A.; Pless, O.
Zeitschriftenaufsatz
2018Microbiome-assisted carrion preservation aids larval development in a burying beetle
Shukla, S.P.; Plata, C.; Reichelt, M.; Steiger, S.; Heckel, D.G.; Kaltenpoth, M.; Vilcinskas, A.; Vogel, H.
Zeitschriftenaufsatz
2018Minimal Disease Activity as a Treatment Target in Psoriatic Arthritis: A Review of the Literature
Gossec, L.; McGonagle, D.; Korotaeva, T.; Lubrano, E.; Miguel, E. de; Østergaard, M.; Behrens, F.
Zeitschriftenaufsatz
2018Minimal disease activity is a stable measure of therapeutic response in psoriatic arthritis patients receiving treatment with adalimumab
Behrens, F.; Koehm, M.; Schwaneck, E.C.; Schmalzing, M.; Gnann, H.; Greger, G.; Tony, H.P.; Burkhardt, H.
Zeitschriftenaufsatz
2018Mitochondrial fragmentation in human macrophages attenuates palmitate-induced inflammatory responses
Zezina, E.; Snodgrass, R.G.; Schreiber, Y.; Zukunft, S.; Schürmann, C.; Meyer zu Heringdorff, D.; Geisslinger, G.; Fleming, I.; Brandes, R.P.; Brüne, B.; Namgaladze, D.
Zeitschriftenaufsatz
2018Molecular techniques for the detection and identification of yeasts in wine
Diaz, Cecilia; Badalyan, Grigori; Bücking, Mark
Aufsatz in Buch
2018Molecular tools to create new strains for mosquito sexing and vector control
Häcker, I.; Schetelig , M.F.
Zeitschriftenaufsatz
2018Mutations in PMPCB Encoding the Catalytic Subunit of the Mitochondrial Presequence Protease Cause Neurodegeneration in Early Childhood
Vögtle, F.-N.; Brändl, B.; Larson, A.; Pendziwiat, M.; Friederich, M.W.; White, S.M.; Basinger, A.; Kücükköse, C.; Muhle, H.; Jähn, J.A.; Keminer, O.; Helbig, K.L.; Delto, C.F.; Myketin, L.; Mossmann, D.; Burger, N.; Miyake, N.; Burnett, A.; Baalen, A. van; Lovell, M.A.; Matsumoto, N.; Walsh, M.; Yu, H.-C.; Shinde, D.N.; Stephani, U.; Hove, J.L.K. van; Müller, F.-J.; Helbig, I.
Zeitschriftenaufsatz
2018Mutual inversion of flurbiprofen enantiomers in various rat and mouse strains
Bruin, N. de; Ferreirós, N.; Schmidt, M.; Hofmann, M.; Angioni, C.; Geisslinger, G.; Parnham, M.J.
Zeitschriftenaufsatz
2018Nanomaterials: Certain aspects of application, risk assessment and risk communication
Laux, Peter; Tentschert, Jutta; Riebeling, Christian; Braeuning, Albert; Creutzenberg, Otto; Epp, Astrid; Fessard, Valérie; Haas, Karl-Heinz; Haase, Andrea; Hund-Rinke, Kerstin; Jakubowski, Norbert; Kearns, Peter; Lampen, Alfonso; Rauscher, Hubert; Schoonjans, Reinhilde; Störmer, Angela; Thielmann, Axel; Mühle, Uwe; Luch, Andreas
Zeitschriftenaufsatz
2018Nanopharmaceuticals for wound healing
Ashtikar, M.; Wacker, M.G.
Zeitschriftenaufsatz
2018Non-invasive bioluminescence imaging as a standardized assessment measure in mouse models of dermal inflammation
Hofmann, M.C.J.; Schmidt, M.; Arne, O.; Geisslinger, G.; Parnham, M.J.; Bruin, N.M.W.J. de
Zeitschriftenaufsatz
2018Novel Biomarkers for diagnosis and progression of primary progressive multiple sclerosis (PPMS)
Friese, Manuel; Pleß, Ole; Schauer, Nicolas; Stoessel, Daniel
Patent
2018A Novel Function for 15-Lipoxygenases in Cholesterol Homeostasis and CCL17 Production in Human Macrophages
Snodgrass, R.G.; Zezina, E.; Namgaladze, D.; Gupta, S.; Angioni, C.; Geisslinger, G.; Lütjohann, D.; Brüne, B.
Zeitschriftenaufsatz
2018Novel sensor platform for rapid detection and quantification of coliforms on food contact surfaces
Badalyan, Grigori; Diaz, Cecilia; Bücking, Mark; Lipski, André
Zeitschriftenaufsatz
2018Nutritional immunology: Diversification and diet-dependent expression of antimicrobial peptides in the black soldier fly Hermetia illucens
Vogel, H.; Müller, A.; Heckel, D.G.; Gutzeit, H.; Vilcinskas, A.
Zeitschriftenaufsatz
2018On the relationship of anthranilic derivatives structure and the FXR (Farnesoid X receptor) agonist activity
Kronenberger, T.; Windshügel, B.; Wrenger, C.; Honorio, K.M.; Maltarollo, V.G.
Zeitschriftenaufsatz
2018Optimizing the composition of a synthetic cellulosome complex for the hydrolysis of softwood pulp
Leis, B.; Held, C.; Andreeßen, B.; Liebl, W.; Graubner, S.; Schulte, L.-P.; Schwarz, W.H.; Zverlov, V.V.
Zeitschriftenaufsatz
2018Oral plasma kallikrein inhibitor for prophylaxis in hereditary angioedema
Aygören-Pürsün, E.; Bygum, A.; Grivcheva-Panovska, V.; Magerl, M.; Graff, J.; Steiner, U.C.; Fain, O.; Huissoon, A.; Kinaciyan, T.; Farkas, H.; Lleonart, R.; Longhurst, H.J.; Rae, W.; Triggiani, M.; Aberer, W.; Cancian, M.; Zanichelli, A.; Smith, W.B.; Baeza, M.L.; Du-Thanh, A.; Gompels, M.; Gonzalez-Quevedo, T.; Greve, J.; Guilarte, M.; Katelaris, C.; Dobo, S.; Cornpropst, M.; Clemons, D.; Fang, L.; Collis, P.; Sheridan, W.; Maurer, M.; Cicardi, M.
Zeitschriftenaufsatz
2018The oxidized linoleic acid metabolite 12,13-DiHOME mediates thermal hyperalgesia during inflammatory pain
Zimmer, B.; Angioni, C.; Osthues, T.; Toewe, A.; Thomas, D.; Pierre, S.C.; Geisslinger, G.; Scholich, K.; Sisignano, M.
Zeitschriftenaufsatz
2018Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells
Hitzel, J.; Lee, E.; Zhang, Y.; Bibli, S.I.; Li, X.; Zukunft, S.; Pflüger, B.; Hu, J.; Schürmann, C.; Vasconez, A.E.; Oo, J.A.; Kratzer, A.; Kumar, S.; Rezende, F.; Josipovic, I.; Thomas, D.; Giral, H.; Schreiber, Y.; Geisslinger, G.; Fork, C.; Yang, X.; Sigala, F.; Romanoski, C.E.; Kroll, J.; Jo, H.; Landmesser, U.; Lusis, A.J.; Namgaladze, D.; Fleming, I.; Leisegang, M.S.; Zhu, J.; Brandes, R.P.
Zeitschriftenaufsatz
2018Pathophysiological mechanisms of neuropathic pain: comparison of sensory phenotypes in patients and human surrogate pain models
Vollert, J,; Magerl, W.; Baron, R.; Binder, A.; Enax-Krumova, E.; Geisslinger, G.; Gierthmühlen, J.; Henrich, F.; Hüllemann, P.; Klein, T.; Lötsch, J.; Maier, C.; Oertel, B.; Schuh-Hofer, S.; Tölle, T.; Treede, R.-D.
Zeitschriftenaufsatz
2018Physical behavior and sampling of airborne particles
Hochrainer, D.
Aufsatz in Buch
2018Plant-derived chimeric antibodies inhibit the invasion of human fibroblasts by Toxoplasma gondii
Lim, S.S.Y.; Chua, K.H.; Nölke, G.; Spiegel, H.; Goh, W.L.; Chow, S.C.; Kee, B.P.; Fischer, R.; Schillberg, S.; Othman, R.Y.
Zeitschriftenaufsatz
2018Plants as sources of natural and recombinant anti-cancer agents
Buyel, J.F.
Zeitschriftenaufsatz
2018Polyamines delay leaf maturation in low‐alkaloid tobacco varieties
Nölke, G.; Volke, D.; Chudobová, I.; Houdelet, M.; Lusso, M.; Frederick, J.; Adams, A.; Kudithipudi, C.; Warek, U.; Strickland, J.A.; Xu, D.; Schinkel, H.; Schillberg, S.
Zeitschriftenaufsatz
2018Population-specific expression of antimicrobial peptides conferring pathogen resistance in the invasive ladybird Harmonia axyridis
Gegner, T.; Schmidtberg, H.; Vogel, H.; Vilcinskas, A.
Zeitschriftenaufsatz
2018The portal vein as a distinct immunological compartment
Queck, A.; Rueschenbaum, S.; Kubesch, A.; Cai, C.; Zeuzem, S.; Weigert, A.; Brüne, B.; Nour-Eldin, A.; Gruber-Rouh, T.; Vogl, T.; Lange, C.M.
Zeitschriftenaufsatz
2018Primary fish hepatocytes as in vitro test system to study the metabolism of xenobiotics in fish
Bischof, Ina
: Segner, Helmut; Schlechtriem, Christian
Dissertation
2018Promoter construct for cell-free protein synthesis
Buntru, Matthias; Schillberg, Stefan; Vogel, Simon
Patent
2018The prostaglandin E2 receptor EP3 controls CC-chemokine ligand 2–mediated neuropathic pain induced by mechanical nerve damage
Treutlein, E.-M.; Kern, K.; Weigert, A.; Tarighi, N.; Schuh, C.-D.; Nüsing, R.M.; Schreiber, Y.; Ferreirós, N.; Brüne, B.; Geisslinger, G.; Pierre, S.; Scholich, K.
Zeitschriftenaufsatz
2018Proteomic analysis of CHO cell lines producing high and low quantities of a recombinant antibody before and after selection with methotrexate
Hausmann, R.; Chudobová, I.; Spiegel, H.; Schillberg, S.
Zeitschriftenaufsatz
2018Redox-signals and macrophage biology
Weigert, A.; Knethen, A. von; Fuhrmann, D.; Dehne, N.; Brüne, B.
Zeitschriftenaufsatz
2018A reference genome of the Chinese hamster based on a hybrid assembly strategy
Rupp, O.; MacDonald, M.L.; Li, S.; Dhiman, H.; Polson, S.; Griep, S.; Heffner, K.; Hernandez, I.; Brinkrolf, K.; Jadhav, V.; Samoudi, M.; Hao, H.; Kingham, B.; Goesmann, A.; Betenbaugh, M.J.; Lewis, N.E.; Borth, N.; Lee, K.H.
Zeitschriftenaufsatz
2018The relevance of ceramides and their synthesizing enzymes for multiple sclerosis
Kurz, J.; Brunkhorst, R.; Foerch, C.; Blum, L.; Henke, M.; Gabriel, L.; Ulshöfer, T.; Ferreiros, N.; Parnham, M.J.; Geisslinger, G.; Schiffmann, S.
Zeitschriftenaufsatz
2018Reliability of In Vitro Methods Used to Measure Intrinsic Clearance of Hydrophobic Organic Chemicals by Rainbow Trout
Nichols, John; Fay, Kellie; Bernhard, Mary Jo; Bischof, Ina; Davis, John; Halder, Marlies; Hu, Jing; Johanning, Karla; Laue, Heike; Nabb, Diane; Schlechtriem, Christian; Segner, Helmut; Swintek, Joe; Weeks, John; Embry, Michelle
Zeitschriftenaufsatz
2018Reliable high-density energy storage in Si-doped HfO2 thin films on 3D-structures
Kühnel, Kati; Riedel, Stefan; Mart, Clemens; Weinreich, Wenke
Vortrag
2018Response of the Mayfly (Cloeon Dipterum) to chronic exposure to Thiamethoxam in outdoor Mesocosms
Pickford, Daniel B.; Finnegan, Meaghean C.; Baxter, Leilan R.; Böhmer, Walter; Hanson, Mark L.; Stegger, Petra; Hommen, Udo; Hoekstra, Paul F.; Hamer, Mick
Zeitschriftenaufsatz
2018Revisiting elimination half live as an indicator for bioaccumulation in fish and terrestrial mammals
Goss, Kai-Uwe; Linden, Lukas; Ulrich, Nadin; Schlechtriem, Christian
Zeitschriftenaufsatz
2018S2e-Leitlinie: Therapie der rheumatoiden Arthritis mit krankheitsmodifizierenden Medikamenten
Fiehn, C.; Holle, J.; Iking-Konert, C.; Leipe, J.; Weseloh, C.; Frerix, M.; Alten, R.; Behrens, F.; Baerwald, C.; Braun, J.; Burkhardt, H.; Burmester, G.; Detert, J.; Gaubitz, M.; Gause, A.; Gromnica-Ihle, E.; Kellner, H.; Krause, A.; Kuipers, J.; Lorenz, H.-M.; Müller-Ladner, U.; Nothacker, M.; Nüsslein, H.; Rubbert-Roth, A.; Schneider, M.; Schulze-Koops, H.; Seitz, S.; Sitter, H.; Specker, C.; Tony, H.-P.; Wassenberg, S.; Wollenhaupt, J.; Krüger, K.
Zeitschriftenaufsatz
2018Safety and efficacy of ixekizumab in patients with PsA and previous inadequate response to TNF inhibitors: week 52 results from SPIRIT-P2
Genovese, M.C.; Combe, B.; Kremer, J.M.; Tsai, T.-F.; Behrens, F.; Adams, D.H.; Lee, C.; Kerr, L.; Nash, P.
Zeitschriftenaufsatz
2018Scientific Opinion about the Guidance of the Chemical Regulation Directorate (UK) on how aged sorption studies for pesticides should be conducted, analysed and used in regulatory assessments
Ockleford, Colin; Hernandez-Jerez, Antonio F.; Hougaard Bennekou, Susanne; Klein, Michael; et. al.
Zeitschriftenaufsatz
2018Scientific opinion on pesticides in foods for infants and young children
Ockleford, Colin; Adriaanse, Paulien; Hougaard Bennekou, Susanne; Berny, Philippe; Brock, Theodorus; Duquesne, Sabine; Grilli, Sandro; Hernandez-Jerez, Antonio F.; Klein, Michael; Kuhl, Thomas; Laskowski, Ryszard; Machera, Kyriaki; Pelkonen, Olavi; Pieper, Silvia; Smith, Robert; Stemmer, Michael; Sundh, Ingvar; Teodorovic, Ivana; Tiktak, Aaldrik; Topping, Chris J.; Gundert-Remy, Ursula; Kersting, Mathilde; Waalkens-Berendsen, Ine; Chiusolo, Arianna; Court Marques, Daniele; Dujardin, Bruno; Kass, Georges E; Mohimont, Luc; Nougadere, Alexandre; Reich, Hermine; Wolterink, Gerrit
Zeitschriftenaufsatz
2018Scientific Opinion on the state of the art of Toxicokinetic/Toxicodynamic (TKTD) effect models for regulatory risk assessment of pesticides for aquatic organisms
Ockleford, Colin; Adriaanse, Paulien; Berny, Philippe; Brock, Theodorus; Duquesne, Sabine; Grilli, Sandro; Hernandez-Jerez, Antonio F.; Hougaard Bennekou, Susanne; Klein, Michael; et. al.
Zeitschriftenaufsatz
2018Scientific Opinion on the state of the science on pesticide risk assessment for amphibians and reptiles
Ockleford, Colin; Adriaanse, Paulien; Berny, Philippe; Brock, Theodorus; Duquesne, Sabine; Grilli, Sandro; Hernandez-Jerez, Antonio F.; Hougaard Bennekou, Susanne; Klein, Michael; Kuhl, Thomas; Laskowski, Ryszard; Machera, Kyriaki; Pelkonen, Olavi; Pieper, Silvia; Stemmer, Michael; Sundh, Ingvar; Teodorovic, Ivana; Tiktak, Aaldrik; Topping, Chris J.; Wolterink, Gerrit; Craig, Peter; Jong, Frank de; Manachini, Barbara; Sousa, Paulo; Swarowsky, Klaus; Auteri, Domenica; Arena, Maria; Smith, Rob
Zeitschriftenaufsatz
2018Sicherheit und Wirksamkeitshinweise zum Off-label-Einsatz von Biologikatherapien nach Versagen konventioneller Therapien bei Patienten mit entzündlich rheumatischen Erkrankungen
Proft, F.; Schulze-Koops, H.; Grunke, M.; Schrezenmeier, E.; Halleck, F.; Henes, J.; Unger, L.; Schmidt, E.; Fiehn, C.; Jacobi, A.; Iking-Konert, C.; Kneitz, C.; Schmidt, R.E.; Bannert, B.; Voll, R.E.; Fischer-Betz, R.; Kötter, I.; Tony, H.P.; Holle, J.; Aringer, M.; Erler, A.; Behrens, F.; Burmester, G.R.; Dörner, T.
Zeitschriftenaufsatz
2018Silver nanoparticles in sewage sludge: Bioavailability of sulfidized silver to the terrestrial isopod Porcellio scaber
Kampe, Sebastian; Kägi, Ralf; Schlich, Karsten; Wasmuth, Claus; Hollert, Henner; Schlechtriem, Christian
Zeitschriftenaufsatz
2018Silver nanoparticles in sewage treatment plant effluents: Chronic effects and accumulation of silver in the freshwater amphipod Hyalella azteca
Kühr, Sebastian; Schneider, Stefanie; Meisterjahn, Boris; Schlich, Karsten; Hund-Rinke, Kerstin; Schlechtriem, Christian
Zeitschriftenaufsatz
2018Simultaneous and Independent Dual Site-Specific Self-Labeling of Recombinant Antibodies
Wollschläger, C.; Meinhold-Heerlein, I.; Cong, X.; Bräutigam, K.; Fiore, S. Di; Zeppernick, F.; Klockenbring, T.; Stickeler, E.; Barth, S.; Hussain, A.F.
Zeitschriftenaufsatz
2018Simultaneous determination of PUFA-derived pro-resolving metabolites and pathway markers using chiral chromatography and tandem mass spectrometry
Toewe, A.; Balas, L.; Durand, T.; Geisslinger, G.; Ferreirós, N.
Zeitschriftenaufsatz
2018Simultaneous response in several domains in patients with psoriatic disease treated with etanercept as monotherapy or in combination with conventional synthetic disease-modifying antirheumatic drugs
Behrens, F.; Meier, L.; Prinz, J.C.; Jobst, J.; Lippe, R.; Löschmann, P.-A.; Lorenz, H.-M.
Zeitschriftenaufsatz
2018Single-cell cloning enables the selection of more productive Drosophila melanogaster S2 cells for recombinant protein expression
Zitzmann, J.; Schreiber, C.; Eichmann, J.; Bilz, R.O.; Salzig, D.; Weidner, T.; Czermak, P.
Zeitschriftenaufsatz
2018The siRNA-mediated knockdown of GluN3A in 46C-derived neural stem cells affects mRNA expression levels of neural genes, including known iGluR interactors
Pachernegg, Svenja; Eilebrecht, Sebastian; Eilebrecht, Elke; Schöneborn, Hendrik; Neumann, Sebastian; Benecke, Arndt G.; Hollmann, Michael
Zeitschriftenaufsatz
2018Small rubber particle proteins from Taraxacum brevicorniculatum promote stress tolerance and influence the size and distribution of lipid droplets and artificial poly(cis-1,4-isoprene) bodies
Laibach, N.; Schmidl, S.; Müller, B.; Bergmann, M.; Prüfer, D.; Schulze Gronover, C.
Zeitschriftenaufsatz
2018The sneaking ligand approach for cell type-specific modulation of intracellular signalling pathways
Sehnert, B.; Burkhardt, H.; Finzel, S.; Dübel, S.; Voll, R.E.
Zeitschriftenaufsatz
2018Sphingosine kinase 2 modulates retinal neovascularization in the mouse model of oxygen-induced retinopathy
Eresch, J.; Stumpf, M.; Koch, A.; Vutukuri, R.; Ferreiros, N.; Schreiber, Y.; Schröder, K.; Devraj, K.; Popp, R.; Huwiler, A.; Hattenbach, L.-O.; Pfeilschifter, J.; Pfeilschifter, W.
Zeitschriftenaufsatz
2018Statistische Auswertung von Messungen zur Kontamination von Biota/Fischen mit Schadstoffen im Einzugsgebiet des Rheins in den Jahren 2014/2015
Fliedner, Annette; Müller, Martin
Bericht
2018Stellenwert der Kombination von Biologika mit Methotrexat in der Behandlung der Psoriasisarthritis - Fragen bleiben offen
Dauth, S.; Köhm, M.; Rossmanith, T.; Herrmann, E.; Lehn, A.; Burkhardt, H.; Behrens, F.
Zeitschriftenaufsatz
2018The structural basis for cancer drug interactions with the catalytic and allosteric sites of SAMHD1
Knecht, K.M.; Buzovetsky, O.; Schneider, C.; Thomas, D.; Srikanth, V.; Kaderali, L.; Tofoleanu, F.; Reiss, K.; Ferreirós, N.; Geisslinger, G.; Batista, V.S.; Ji, X.; Cinatl, J.; Keppler, O.T.; Xiong, Y.
Zeitschriftenaufsatz
2018Structure-activity analysis of CJ-15,801 analogues that interact with Plasmodium falciparum pantothenate kinase and inhibit parasite proliferation
Spry, C.; Sewell, A.L.; Hering, Y.; Villa, M.V.J.; Weber, J.; Hobson, S.J.; Harnor, S.J.; Gul, S.; Marquez, R.; Salib, K.J.
Zeitschriftenaufsatz
2018Synaptic phospholipids as a new target for cortical hyperexcitability and E/I balance in psychiatric disorders
Thalman, C.; Horta, G.; Qiao, L.; Endle, H.; Tegeder, I.; Cheng, H.; Laube, G.; Sigurdsson, T.; Hauser, M.J.; Tenzer, S.; Distler, U.; Aoki, J.; Morris, A.J.; Geisslinger, G.; Röper, J.; Kirischuk, S.; Luhmann, H.J.; Radyushkin, K.; Nitsch, R.; Vogt, J.
Zeitschriftenaufsatz
2018T Cell Phenotype and T Cell Receptor Repertoire in Patients with Major Depressive Disorder
Patas, K.; Willing, A.; Demiralay, C.; Engler, J.B.; Lupu, A.; Ramien, C.; Schäfer, T.; Gach, C.; Stumm, L.; Chan, K.; Vignali, M.; Arck, P.C.; Friese, M.A.; Pless, O.; Wiedemann, K.; Agorastos, A.; Gold, S.M.
Zeitschriftenaufsatz
2018Taraxacum brevicorniculatum rubber elongation factor TbREF associates with lipid droplets and affects lipid turn-over in yeast
Bröker, J.N.; Laibach, N.; Müller, B.; Prüfer, D.; Schulze Gronover, C.
Zeitschriftenaufsatz
2018Therapeutics discovery: From bench to first in-human trials
Al-Hujaily, E.M.; Khatlani, T.; Alehaideb, Z.; Ali, R.; Almuzaini, B.; Alrfaei, B.M.; Iqbal, J.; Islam, I.; Malik, S.; Marwani, B.A.; Massadeh, S.; Muzaini, B.; Nehdi, A.; Alsomaie, B.; Debasi, B.; Bushnak, I.; Noibi, S.; Hussain, S.; Wajid, W.A.; Armand, J.-P.; Gul, S.; Oyarzabal, J.; Rais, R.; Bountra, C.; Alaskar, A.; Al Knawy, B.; Boudjelal, M.
Zeitschriftenaufsatz
2018Three-Dimensional Bioreactor Technologies for the Cocultivation of Human Mesenchymal Stem/Stromal Cells and Beta Cells
Petry, F.; Weidner, T.; Czermak, P.; Salzig, D.
Zeitschriftenaufsatz
2018Total Synthesis and Structural Revision of the Antibiotic Tetrapeptide GE81112A
Jürjens, G.; Schuler, S.M.M.; Kurz, M.; Petit, S.; Couturier, C.; Jeannot, F.; Nguyen, F.; Wende, R.C.; Hammann, P.E.; Wilson, D.N.; Bacqué, E.; Pöverlein, C.; Bauer, A.
Zeitschriftenaufsatz
2018Two-pronged approach to anti-inflammatory therapy through the modulation of the arachidonic acid cascade
Sala, A.; Proschak, E.; Steinhilber, D.; Rovati, G.E.
Zeitschriftenaufsatz
2018UDP-glucose ceramide glucosyltransferase activates AKT, promoted proliferation, and doxorubicin resistance in breast cancer cells
Wegner, M.-S.; Schömel, N.; Gruber, L.; Örtel, S.B.; Kjellberg, M.A.; Mattjus, P.; Kurz, J.; Trautmann, S.; Peng, B.; Wegner, M.; Kaulich, M.; Ahrends, R.; Geisslinger, G.; Grösch, S.
Zeitschriftenaufsatz
2018The UDP-glucose ceramide glycosyltransferase (UGCG) and the link to multidrug resistance protein 1 (MDR1)
Wegner, M.-S.; Gruber, L.; Mattjus, P.; Geisslinger, G.; Grösch, S.
Zeitschriftenaufsatz
2018A unique fungal strain collection from Vietnam characterized for high performance degraders of bioecological important biopolymers and lipids
Brandt, S.C.; Ellinger, B.; Nguyen, T. van; Thi, Q.D.; Nguyen, G. van; Baschien, C.; Yurkov, A.; Hahnke, R.L.; Schäfer, W.; Gand, M.
Zeitschriftenaufsatz
2018Untersuchungen zur Regulation der Leukotrien-Biosynthese durch Sphingosin-1-Phosphat
Fettel, J.
Dissertation
2018Upregulating the mevalonate pathway and repressing sterol synthesis in Saccharomyces cerevisiae enhances the production of triterpenes
Bröker, J.N.; Müller, B.; Deenen, N. van; Prüfer, D.; Schulze Gronover, C.
Zeitschriftenaufsatz
2018Uptake and effects of cerium(III) and cerium oxide nanoparticles to Chlamydomonas reinhardtii
Kosak, Lena A.; Brandt, Tanja; Sigg, Laura; Behra, Renata
Zeitschriftenaufsatz
2018Urate transporter inhibitor lesinurad is a selective peroxisome proliferator-activated receptor gamma modulator (sPPARγM) in vitro
Heitel, P.; Gellrich, L.; Heering, J.; Goebel, T.; Kahnt, A.; Proschak, E.; Schubert-Zsilavecz, M.; Merk, D.
Zeitschriftenaufsatz
2018Urate transporter inhibitor lesinurad is a selective peroxisome proliferator-activated receptor gamma modulator (sPPARγM) in vitro
Heitel, P.; Gellrich, L.; Heering, J.; Goebel, T.; Kahnt, A.; Proschak, E.; Schubert-Zsilavecz, M.; Merk, D.
Zeitschriftenaufsatz
2018Use of Computational Functional Genomics in Drug Discovery and Repurposing for Analgesic Indications
Lötsch, J.; Kringel, D.
Zeitschriftenaufsatz
2018When facing multiple enemies: the impact of host development time and exposure to multiple parasites in shaping coevolutionary adaptations in host and parasites
Biswas, T.
Dissertation

 

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