Fraunhofer-Gesellschaft

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Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
20193D Printed Modular Immunofiltration Columns for Frequency Mixing-Based Multiplex Magnetic Immunodetection
Achtsnicht, S.; Tödter, J.; Niehues, J.; Telöken, M.; Offenhäusser, A.; Krause, H.J.; Schröper, F.
Zeitschriftenaufsatz
2019α-Amino Diphenyl Phosphonates as Novel Inhibitors of Escherichia coli ClpP Protease
Moreno-Cinos, C.; Sassetti, E.; Salado, I.G.; Witt, G.; Benramdane, S.; Reinhardt, L.; Cruz, C.D.; Joossens, J.; Veken, P. Van der; Brötz-Oesterhe, H.; Tammela, P.; Winterhalter, M.; Gribbon, P.; Windshügel, B.; Augustyns, K.
Zeitschriftenaufsatz
2019Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform
Moraes, C.B.; Witt, G.; Kuzikov, M.; Ellinper, B.; Calogeropoulou, T.; Prousis, K.C.; Mangani, S.; Pisa, F. di; Landi, G.; Dello Lacono, L.; Pozzi, C.; Freitas, L.H.; Pascoalino, B.D.; Bertolacini, C.P.; Behrens, B.; Keminer, O.; Leu, J.; Wolf, M.; Reinshagen, J.; Cordeiro-da-Silva, A.; Santarem, N.; Venturelli, A.; Wrigley, S.; Karunakaran, D.; Kebede, B.; Pohner, I.; Muller, W.; Panecka-Hofman, J.; Wade, R.C.; Fenske, M.; Clos, J.; Alunda, J.M.; Corral, M.J.; Uliassi, E.; Bolognesi, M.L.; Linciano, P.; Quotadamo, A.; Ferrari, S.; Santucci, M.; Borsari, C.; Costi, M.P.; Gul, S.
Zeitschriftenaufsatz
2019ADAM15 in Apoptosis Resistance of Synovial Fibroblasts
Janczi, T.; Böhm, B.B.; Fehrl, Y.; DeGiacomo, P.; Kinne, R.W.; Burkhardt, H.
Zeitschriftenaufsatz
2019Alternativen zum Wachstum
Schäfers, Christoph; Bette, Kristina; Herrmann, Florian; Nawroth, Georg
Aufsatz in Buch
2019Bioconcentration studies with the freshwater amphipod Hyalella azteca: Are the results predictive of bioconcentration in fish?
Schlechtriem, Christian; Kampe, Sebastian; Bruckert, Hans-Jörg; Bischof, Ina; Ebersbach, Ina; Kosfeld, Verena; Kotthoff, Matthias; Schäfers, Christoph; L’Haridon, Jacques
Zeitschriftenaufsatz
2019Biodegradation of Volatile Chemicals in Soil: Separating Volatilization and Degradation in an Improved Test Setup (OECD 307)
Shrestha, Prasit; Meisterjahn, Boris; Klein, Michael; Mayer, Philipp; Birch, Heidi; Hughes, Christopher B.; Hennecke, Dieter
Zeitschriftenaufsatz
2019Biosynthetic Basis for Structural Diversity of Aminophenylpyrrole-Derived Alkaloids
Linares-Otoya, L.; Liu, Y.; Linares-Otoya, V.; Armas-Mantilla, L.; Crüsemann, M.; Ganoza-Yupanqui, M.L.; Campos-Florian, J.; König, G.M.; Schäberle, T.F.
Zeitschriftenaufsatz
2019Ceramides as Novel Disease Biomarkers
Kurz, J.; Parnham, M.J.; Geisslinger, G.; Schiffmann, S.
Zeitschriftenaufsatz
2019Chronic Hypoxia Enhances β-Oxidation-Dependent Electron Transport via Electron Transferring Flavoproteins
Fuhrmann, D.C.; Olesch, C.; Kurrle, N.; Schnütgen, F.; Zukunft, S.; Fleming, I.; Brüne, B.
Zeitschriftenaufsatz
2019Circular synthesized CRISPR/Cas gRNAs for functional interrogations in the coding and noncoding genome
Wegner, M.; Diehl, V.; Bittl, V.; Bruyn, R. de; Wiechmann, S.; Matthess, Y.; Heber, M.; Hayes, M.G.B.; Schaubeck, S.; Benner, C.; Heinz, S.; Bremm, A.; Dikic, I.; Ernst, A.; Kaulich, M.
Zeitschriftenaufsatz
2019A Combined Ultrafiltration/Diafiltration Step Facilitates the Purification of Cyanovirin-N From Transgenic Tobacco Extracts
Opdensteinen, P.; Clodt, J.I.; Müschen, C.R.; Filiz, V.; Buyel, J.F.
Zeitschriftenaufsatz
2019Comparative estrogenicity of endogenous, environmental and dietary estrogens in pregnant women II
Pande, P.; Fleck, S.C.; Twaddle, N.C.; Churchwell, M.I.; Doerge, D.R.; Teeguarden, J.G.
Zeitschriftenaufsatz
2019A comparison of log Kow (n‑octanol-water partition coefficient) values for non‑ionic, anionic, cationic and amphoteric surfactants determined using predictions and experimental methods
Hodges, Geoff; Eadsforth, Charles; Bossuyt, Bart; Bouvy, Alain; Enrici, Marie‑Helene; Geurts, Marc; Kotthoff, Matthias; Michie, Eleanor; Miller, Dennis; Müller, Josef; Oetter, Gunter; Roberts, Jayne; Schowanek, Diederik; Sun, Ping; Venzmer, Joachim
Zeitschriftenaufsatz
2019Comparison of the environmental properties of parasiticides and harmonisation of the basis for environmental assessment at the EU level
Römbke, Jörg; Duis, Karen; Egeler, Philipp; Gilberg, Daniel; Schuh, Christine; Herrchen, Monika; Hennecke, Dieter; Hölzle, Ludwig E.; Heilmann-Thudium, Brigitte; Wohde, Manuel; Wagner, Julia; Düring, Rolf-Alexander
Bericht
2019Computer-Assisted Discovery and Structural Optimization of a Novel Retinoid X Receptor Agonist Chemotype
Heitel, P.; Gellrich, L.; Kalinowsky, L.; Heering, J.; Kaiser, A.; Ohrndorf, J.; Proschak, E.; Merk, D.
Zeitschriftenaufsatz
2019The Correlation Between DsRed mRNA Levels and Transient DsRed Protein Expression in Plants Depends on Leaf Age and the 5′ Untranslated Region
Jansing, J.; Buyel, J.F.
Zeitschriftenaufsatz
2019A Data Science-Based Analysis Points at Distinct Patterns of Lipid Mediator Plasma Concentrations in Patients with Dementia
Gurke, R.; Etyemez, S.; Prvulovic, D.; Thomas, D.; Fleck, S.C.; Reif, A.; Geisslinger, G.; Lötsch, J.
Zeitschriftenaufsatz
2019Development study of pectin/Surelease® solid microparticles for the delivery of L-alanyl-L-glutamine dipeptide
Nova, M.V.; Nothnagel, L.; Thurn, M.; Travassos, P.B.; Herculano, L.S.; Bittencourt, P.R.S.; Novello, C.R.; Bazotte, R.B.; Wacker, M.G.; Bruschi, M.L.
Zeitschriftenaufsatz
2019Downstream processing of Cry4AaCter-induced inclusion bodies containing insect-derived antimicrobial peptides produced in Escherichia coli
Hoffmann, D.; Eckhardt, D.; Gerlach, D.; Vilcinskas, A.; Czermak, P.
Zeitschriftenaufsatz
2019Driving next-generation autophagy researchers towards translation (DRIVE), an international PhD training program on autophagy
Kraft, C.; Boya, P.; Codogno, P.; Elazar, Z.; Eskelinen, E.-L.; Farres, J.; Kirkin, V.; Jungbluth, H.; Martinez, A.; Pless, O.; Primard, C.; Proikas-Cezanne, T.; Simonsen, A.; Reggiori, F.
Zeitschriftenaufsatz
2019Effects of continuous theta-burst stimulation of the primary motor and secondary somatosensory areas on the central processing and the perception of trigeminal nociceptive input in healthy volunteers
Annak, O.; Heidegger, T.; Walter, C.; Deichmann, R.; Nöth, U.; Hansen-Goos, O.; Ziemann, U.; Lötsch, J.
Zeitschriftenaufsatz
2019Elucidation of chemical modifier reactivity towards peptides and proteins and the analysis of specific fragmentation by matrix‐assisted laser desorption/ionization collision‐induced dissociation tandem mass spectrometry
Rühl, M.; Kühn, B.; Roos, J.; Maier, T.J.; Steinhilber, D.; Karas, M.
Zeitschriftenaufsatz, Konferenzbeitrag
2019The enzymes OSC1 and CYP716A263 produce a high variety of triterpenoids in the latex of Taraxacum koksaghyz
Pütter, K.M.; Deenen, N. van; Müller, B.; Fuchs, L.; Vorwerk, K.; Unland, K.; Bröker, J.N.; Scherer, E.; Huber, C.; Eisenreich, W.; Prüfer, D.; Schulze Gronover, C.
Zeitschriftenaufsatz
2019Epigenetic Mechanisms Are Involved in Sex-Specific Trans-Generational Immune Priming in the Lepidopteran Model Host Manduca sexta
Gegner, J.; Baudach, A.; Mukherjee, K.; Halitschke, R.; Vogel, H.; Vilcinska, A.
Zeitschriftenaufsatz
2019Epigenetic mechanisms mediate the experimental evolution of resistance against parasitic fungi in the greater wax moth Galleria mellonella
Mukherjee, K.; Dubovskiy, I.; Grizanova, E.; Lehmann, R.; Vilcinskas, A.
Zeitschriftenaufsatz
2019EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology
Brennecke, P.; Rasina, D.; Aubi, O.; Herzog, K.; Landskron, J.; Cautain, B.; Vicente, F.; Quintana, J.; Mestres, J.; Stechmann, B.; Ellinger, B.; Brea, J.; Kolanowski, JL.; Pilarski, R.; Orzaez, M.; Pineda-Lucena, A.; Laraia, L.; Nami, F.; Zielenkiewicz, P.; Paruch, K.; Hansen, E.; von Kries, J.P.; Neuenschwander, M.; Specker, E.; Bartunek, P.; Simova, S.; Lesnikowski, Z.; Krauss, S.; Lehtio, L.; Bilitewski, U.; Bronstrup, M.; Tasken, K.; Jirgensons, A.; Lickert, H.; Clausen, M.H.; Andersen, J.H.; Vicent, M.J.; Genilloud, O.; Martinez, A.; Nazare, M.; Fecke, W.; Gribbon, P.
Zeitschriftenaufsatz
2019Evolutionary ecology of parasitic fungi and their host insects
Vilcinskas, A.
Zeitschriftenaufsatz
2019First evidence of anticoagulant rodenticides in fish and suspended particulate matter: Spatial and temporal distribution in German freshwater aquatic systems
Kotthoff, Matthias; Rüdel, Heinz; Jürling, Heinrich; Severin, Kevin; Hennecke, Stephan; Friesen, Anton; Koschorreck, Jan
Zeitschriftenaufsatz
2019Förderung der Wiederbepflanzung von Windbruchflächen im Sauerland
Drabkin, Dimitri; Weinfurtner, Karlheinz
Aufsatz in Buch
2019Fraunhofer-Institut für Molekularbiologie und Angewandte Oekologie. Jahresbericht 2018
 
Jahresbericht
2019Generation of transgenic cell suspension cultures of the model legume Medicago truncatula: A rapid method for Agrobacterium mediated gene transfer
Santos, Rita B.; Pires, Ana Sofia; Hoorn, Renier A.L. van der; Schiermeyer, Andreas; Abranches, Rita
Zeitschriftenaufsatz
2019Genome Editing in Agriculture: Technical and Practical Considerations
Jansing, Julia; Schiermeyer, Andreas; Schillberg, Stefan; Fischer, Rainer; Bortesi, Luisa
Zeitschriftenaufsatz
2019Genomic targeting by recombinase‐mediated cassette exchange in the spotted wing drosophila, Drosophila suzukii
Schetelig, M.F.; Yan, Y.; Zhao, Y.; Handler, A.M.
Zeitschriftenaufsatz
2019Histone Deacetylation Inhibitors as Therapy Concept in Sepsis. Review
Knethen, A. von; Brüne, B.
Zeitschriftenaufsatz
2019Imatinib stimulates prostaglandin E2 and attenuates cytokine release via EP4 receptor activation
Bärnthaler, T.; Jandl, K.; Sill, H.; Uhl, B.; Schreiber, Y.; Grill, M.; Thomas, D.; Schicho, R.; Marsche, G.; Frank, S.; Heinemann, A.; Schuligoi, R.
Zeitschriftenaufsatz
2019The immunome of soy bean allergy: Comprehensive identification and characterization of epitopes
Kern, Karolin; Havenith, Heide; Delaroque, Nicolas; Rautenberger, Paul; Lehmann, Jörg; Fischer, Markus; Spiegel, Holger; Schillberg, Stefan; Ehrentreich-Förster, Eva; Aurich, Stefanie; Treudler, Regina; Szardenings, Michael
Zeitschriftenaufsatz
2019Inhibition of the protein kinase IKKepsilon attenuates neuropathic pain in mice
Möser, C.V.; Möller, M.; Fleck, S.C.; Thomas, D.; Geisslinger, G.; Niederberger, E.
Zeitschriftenaufsatz
2019Insektenbiotechnologie: Insekten als Ressource
Vilcinskas, Andreas
Aufsatz in Buch
2019The Integration of Algal Carbon Concentration Mechanism Components into Tobacco Chloroplasts Increases Photosynthetic Efficiency and Biomass
Nölke, G.; Barsoum, M.; Houdelet, M.; Arcalis, E.; Kreuzaler, F.; Fischer, R.; Schillberg, S.
Zeitschriftenaufsatz
2019Iron as a Central Player and Promising Target in Cancer Progression. Review
Jung, M.; Mertens, C.; Tomat, E.; Brüne, B.
Zeitschriftenaufsatz
2019Laccase-induced HBT-grafting to milled beech wood reduces unspecific protein adsorption
Jestel, T.; Roth, S.; Heesel, D.; Kress, A.; Fischer, R.; Spiess, A.C.
Zeitschriftenaufsatz
2019Levels, accumulation patterns and retrospective trends of perfluoroalkyl acids (PFAAs) in terrestrial ecosystems over the last three decades
Falk, Sandy; Stahl, Thorsten; Fliedner, Annette; Rüdel, Heinz; Tarricone, Kathrin; Brunn, Hubertus; Koschorreck, Jan
Zeitschriftenaufsatz
2019Machine Learning in Human Olfactory Research
Lötsch, J.; Kringel, D.; Hummel, T.
Zeitschriftenaufsatz
2019Nutzung der Erfahrungen und Ergebnisse des Biotamonitorings der Umweltprobenbank für die Umsetzung des WRRL-Fischmonitorings
Fliedner, Annette; Rüdel, Heinz; Koschorreck, Jan
Zeitschriftenaufsatz
2019Omega-3 and -6 fatty acid plasma levels are not associated with liver cirrhosis-associated systemic inflammation
Schwarzkopf, K.M.; Queck, A.; Thomas, D.; Angioni, C.; Cai, C.; Freygang, Y.; Rüschenbaum, S.; Geisslinger, G.; Zeuzem, S.; Welsch, C.; Lange, C.M.
Zeitschriftenaufsatz
2019Organismen als Produzenten: Produktion von Wertstoffen mithilfe von Mikroorganismen, Algen und Pflanzenzellen
Rasche, Stefan; Schillberg, Stefan; Derwenskus, Felix; Schmid-Staiger, Ulrike; Schließmann, Ursula
Aufsatz in Buch
2019Passive equilibrium sampling of hydrophobic organic compounds in homogenised fish tissues of low lipid content
Rojo-Nieto, Elisa; Muz, Melis; Koschorreck, Jan; Rüdel, Heinz; Jahnke, Annika
Zeitschriftenaufsatz
2019Plant Molecular Farming - Integration and Exploitation of Side Streams to Achieve Sustainable Biomanufacturing
Buyel, J.F.
Zeitschriftenaufsatz
2019Practical advice for selecting or determining trophic magnification factors for application under the European Union water framework directive
Kidd, K.A.; Burkhard, Lawrence P.; Babut, M.; Borgå, Katrine; Muir, Derek C.G.; Perceval, Olivier; Ruedel, Heinz; Woodburn, Kent; Embry, Michelle R.
Zeitschriftenaufsatz
2019Predictive PBPK modeling as a tool in the formulation of the drug candidate TMP-001
Nothnagel, L.; Jung, F.; Rossmanith, T.; Thurn, M.; Ashtikar, M.; Geisslinger, G.; Parnham, M.J.; Wacker, M.G.
Zeitschriftenaufsatz
2019Profiling antimicrobial peptides from the medical maggot Lucilia sericata as potential antibiotics for MDR Gram-negative bacteria
Hirsch, R.; Wiesner, J.; Marker, A.; Pfeifer, Y.; Bauer, A.; Hammann, P.E.; Vilcinskas, A.
Zeitschriftenaufsatz
2019Progress on bringing together raptor collections in Europe for contaminant research and monitoring in relation to chemicals regulation
Movalli, Paola; Duke, Guy; Ramello, Gloria; Dekker, René; Vrezec, Al; Shore, Richard F.; García-Fernández, Antonio; Wernham, Chris; Krone, Oliver; Alygizakis, Nikiforos; Badry, Alexander; Barbagli, Fausto; Biesmeijer, Koos; Boano, Giovanni; Bond, Alexander L.; Choresh, Yael; Bolding Christensen, Jan; Cincinelli, Alessandra; Danielsson, Sara; Dias, Andreia; Dietz, Rune; Eens, Marcel; Espín, Silvia; Eulaers, Igor; Frahnert, Sylke; Fuiz, Tibor I.; Gkotsis, Georgios; Glowacka, Natalia; Gómez-Ramírez, Pilar; Grotti, Marco; Guiraud, Michel; Hosner, Peter; Johansson, Ulf; Jaspers, Veerle L.B.; Kamminga, Pepijn; Koschorreck, Jan; Knopf, Burkhard; Kubin, Eero; LoBrutto, Sabrina; Lourenco, Rui; Martellini, Tania; Martínez-López, Emma; Mateo, Rafael; Nika, Maria-Christina; Nikolopoulou, Varvara; Osborn, Dan; Pauwels, Olivier; Pavia, Marco; Pereira, M. Glória; Rüdel, Heinz; Sanchez-Virosta, Pablo; Slobodnik, Jaroslav; Sonne, Christian; Thomaidis, Nikolaos; Töpfer, Till; Treu, Gabriele; Väinölä, Risto; Valkama,
Zeitschriftenaufsatz
2019Proteomic Analysis of the Venom from the Ruby Ant Myrmica rubra and the Isolation of a Novel Insecticidal Decapeptide
Heep, J.; Klaus, A.; Kessel, T.; Seip, M.; Vilcinskas, A.; Skaljac, M.
Zeitschriftenaufsatz
2019Rating the risks of anticoagulant rodenticides in the aquatic environment: A review
Regnery, Julia; Friesen, Anton; Geduhn, Anke; Göckener, Bernd; Kotthoff, Matthias; Parrhysius, Pia; Petersohn, Eleonora; Reifferscheid, Georg; Schmolz, Erik; Schulz, Robert S.; Schwarzbauer, Jan; Brinke, Marvin
Zeitschriftenaufsatz
2019Reduced neuropathic pain behavior in mice lacking the cyclic nucleotide-gated channel subunit CNGB1
Kallenborn-Gerhardt, W.; Lu, R.; Petersen, J.J.; Metzner, K.; Kuth, M.S.; Heine, S.; Drees, O.; Paul, M.; Becirovic, E.; Kennel, L.; Flauaus, C.; Gross, T.; Wack, G.; Hohmann, S.W.; Turco, D. del; Biel, M.; Geisslinger, G.; Michalakis, S.; Schmidtko, A.
Abstract
2019A response regulator of the OmpR family is part of the regulatory network controlling the oxidative stress response of Rhodobacter sphaeroides
Zhao, Z.; Peng, T.; Oh, J.-I.; Glaeser, J.; Weber, L.; Li, Q.; Klug, G.
Zeitschriftenaufsatz
2019RNAi targeting of rootworm Troponin I transcripts confers root protection in maize
Fishilevich, E.; Bowling, A.J.; Frey, M.L.F.; Wang, P.-H.; Lo, W.; Rangasamy, M.; Worden, S.E.; Pence, H.E.; Gandra, P.; Whitlock, S.L.; Schulenberg, G.; Knorr, E.; Tenbusch, L.; Lutz, J.R.; Novak, S.; Hamm, R.L.; Schnelle, K.D.; Vilcinskas, A.; Narva, K.E.
Zeitschriftenaufsatz
2019Role of ceramide synthase 2 in G-CSF signaling and G-CSF-R translocation into detergent-resistant membranes
Kurz, J.; Barthelmes, J.; Blum, L.; Ulshöfer, T.; Wegner, M.-S.; Ferreiros, N.; Roser, L.; Geisslinger, G.; Grösch, S.; Schiffmann, S.
Zeitschriftenaufsatz
2019Selective Inactivation of Cancer Drugs by SAMHD1 Provides a Molecular Rationale for Therapeutic Stratification in AML
Schneider, C.; Oellerich, T.; Knecht, K.M.; Thomas, D.; Buzovetsky, O.; Schliemann, C.; Bohnenberger, H.; Angenendt, L.; Hartmann, W.; Wardelmann, E.; Scheich, S.; Comoglio, F.; Wilke, A.; Ströbel, P.; Serve, H.; Geisslinger, G.; Keppler, O.T.; Xiong, Y.; Cinatl, J.
Abstract
2019Shooting three inflammatory targets with a single bullet: Novel multi-targeting anti-inflammatory glitazones
Elzahhar, P.A.; Alaaeddine, R.; Ibrahim, T.M.; Nassra, R.; Ismail, A.; Chua, B.S.K.; Frkic, R.L.; Bruning, J.B.; Wallner, N.; Knape, T.; Knethen, A. von; Labib, H.; El-Yazbi, A.F.; Belal, A.S.F.
Zeitschriftenaufsatz
2019Simplified tracking of a soy allergen in processed food using a monoclonal antibody-based sandwich ELISA targeting the soybean 2S albumin gly m 8
Ueberham, Elke; Spiegel, Holger; Havenith, Heide; Rautenberger, Paul; Lidzba, Norbert; Schillberg, Stefan; Lehmann, Jörg
Zeitschriftenaufsatz
2019Stimulating brain recovery after stroke using theranostic albumin nanocarriers loaded with nerve growth factor in combination therapy
Feczkó, T.; Piiper, A.; Ansar, S.; Blixt, F.W.; Ashtikar, M.; Schiffmann, S.; Ulshöfer, T.; Parnham, M.J.; Harel, Y.; Israel, L.L.; Lellouche, J.-P.; Wacker, M.G.
Zeitschriftenaufsatz
2019Symbiont‐mediated chemical defense in the invasive ladybird Harmonia axyridis
Schmidtberg, H.; Shukla, S.P.; Halitschke, R.; Vogel, H.; Vilcinskas, A.
Zeitschriftenaufsatz
2019Synthesis, Biological Evaluation and Structure: Activity Relationships of Diflapolin Analogues as Dual sEH/FLAP Inhibitors
Vieider, L.; Romp, E.; Temml, V.; Fischer, J.; Kretzer, C.; Schoenthaler, M.; Taha, A.; Hernandez-Olmos, V.; Sturm, S.; Schuster, D.; Werz, O.; Garscha, U.; Matuszczak, B.
Zeitschriftenaufsatz
2019Targeted insertion of large DNA sequences by homology-directed repair or non-homologous end joining in engineered tobacco BY-2 cells using designed zinc finger nucleases
Schiermeyer, Andreas; Schneider, Katja; Kirchhoff, Janina; Schmelter, Thomas; Koch, Natalie; Ke, Jiang; Herwartz, Denise; Blue, Ryan; Marri, Pradeep; Samuel, Pon; Corbin, David R.; Webb, Steven R.; Gonzalez, Delkin O.; Folkerts, Otto; Fischer, Rainer; Schinkel, Helga; Ainley, W. Michael; Schillberg, Stefan
Zeitschriftenaufsatz
2019Testing effects of pesticides on macroinvertebrate communities in outdoor stream mesocosms using carbaryl as example test item
Beuter, Liesa‑Kristin; Dören, László; Hommen, Udo; Kotthoff, Matthias; Schäfers, Christoph; Ebke, Klaus-Peter
Zeitschriftenaufsatz
2019The therapeutic potential of the insect metalloproteinase inhibitor against infections caused by Pseudomonas aeruginosa
Eisenhardt, M.; Schlupp, P.; Höfer, F.; Schmidts, T.; Hoffmann, D.; Czermak, P.; Pöppel, A.-K.; Vilcinskas, A.; Runkel, F.
Zeitschriftenaufsatz
2019Thromboxane-Induced α-CGRP Release from Peripheral Neurons Is an Essential Positive Feedback Loop in Capsaicin-Induced Neurogenic Inflammation
Tarighi, N.; Menger, D.; Pierre, S.; Kornstädt, L.; Thomas, D.; Ferreiros, N.; Nüsing, R.M.; Geisslinger, G.; Scholich, K.
Zeitschriftenaufsatz
2019Tolerizing CTL by Sustained Hepatic PD-L1 Expression Provides a New Therapy Approach in Mouse Sepsis
Knethen, A. von; Schäfer, A.; Kuchler, L.; Knape, T.; Christen, U.; Hintermann, E.; Fißlthaler, B.; Schröder, K.; Brandes, R.P.; Genz, B.; Abshagen, K.; Pützer, B.M.; Sha, L.K.; Weigert, A.; Syed, S.N.; Schulz, M.; Shah, A.M.; Ernst, A.; Putyrski, M.; Finkelmeier, F.; Pesic, M.; Greten, F.; Hogardt, M.; Kempf, V.A.J.; Gunne, S.; Parnham, M.J.; Brüne, B.
Zeitschriftenaufsatz
2019Tribolium castaneum as a whole‐animal screening system for the detection and characterization of neuroprotective substances
Brandt, A.; Joop, G.; Vilcinskas, A.
Zeitschriftenaufsatz
2019TRPA1 Sensitization Produces Hyperalgesia to Heat but not to Cold Stimuli in Human Volunteers
Weyer-Menkhoff, I.; Lötsch, J.
Zeitschriftenaufsatz
2019Tunicate-associated bacteria show a great potential for the discovery of antimicrobial compounds
Ayuningrum, D.; Liu, Y.; Riyanti; Sibero, M.T.; Kristiana, R.; Asagabaldan, M.A.; Wuisan, Z.G.; Trianto, A.; Radjasa, O.K.; Sabdono, A.; Schaberle, T.F.
Zeitschriftenaufsatz
2019Tuning Nuclear Receptor Selectivity of Wy14,643 towards Selective Retinoid X Receptor Modulation
Pollinger, J.; Gellrich, L.; Schierle, S.; Kilu, W.; Schmidt, J.; Kalinowsky, L.; Ohrndorf, J.; Kaiser, A.; Heering, J.; Proschak, E.; Merk, D.
Zeitschriftenaufsatz
2019Zafirlukast Is a Dual Modulator of Human Soluble Epoxide Hydrolase and Peroxisome Proliferator-Activated Receptor γ
Göbel, T.; Diehl, O.; Heering, J.; Merk, D.; Angioni, C.; Wittmann, S.K.; Buscato, E. la; Kottke, R.; Weizel, L.; Schader, T.; Maier, T.J.; Geisslinger, G.; Schubert-Zsilavecz, M.; Steinhilber, D.; Proschak, E.; Kahnt, A.S.
Zeitschriftenaufsatz
201820-HETE promotes glucose-stimulated insulin secretion in an autocrine manner through FFAR1
Tunaru, S.; Bonnavion, R.; Brandenburger, I.; Preussner, J.; Thomas, D.; Scholich, K.; Offermanns, S.
Zeitschriftenaufsatz
20188-Methoxypsoralen Plus Ultraviolet A Reduces the Psoriatic Response to Imiquimod in a Murine Model
Shirsath, N.; Wagner, K.; Tangermann, S.; Schlederer, M.; Ringel, C.; Kenner, L.; Brüne, B.; Wolf, P.
Zeitschriftenaufsatz
2018Abatacept used in combination with non-methotrexate disease-modifying antirheumatic drugs
Alten, R.; Burkhardt, H.; Feist, E.; Krüger, K.; Rech, J.; Rubbert-Roth, A.; Voll, R.E.; Elbez, Y.; Rauch, C.
Zeitschriftenaufsatz
2018Achieving adequate protection and suitable food safety indicators
Pucher, J.; Schlechtriem, Christian
Aufsatz in Buch
2018Activation of Adenylyl Cyclase Causes Stimulation of Adenosine Receptors
Pleli, T.; Mondorf, A.; Ferreiros, N.; Thomas, D.; Dvorak, K.; Biondi, R.M.; Heringdorf, D.M.; Zeuzem, S.; Geisslinger, G.; Zimmermann, H.; Waidmann, O.; Piiper, A.
Zeitschriftenaufsatz
2018Advances and Challenges in Drug Design of PPARδ Ligands
Maltarollo, V.G.; Kronenberger, T.; Windshugel, B.; Wrenger, C.; Goulart Trossini, G.H.; Honorio, K.M.
Zeitschriftenaufsatz
2018Advances in the development of procedures to establish the toxicity of non-extractable residues (NER) in soil. LRI-ECO25
Harmsen, Joop; Hennecke, Dieter; Hund-Rinke, Kerstin; Lahr, Joost; Deneer, John
Bericht
2018AICAR inhibits NFκB DNA binding independently of AMPK to attenuate LPS-triggered inflammatory responses in human macrophages
Kirchner, J.; Brüne, B.; Namgaladze, D.
Zeitschriftenaufsatz
2018Analysis and Optimization of Ecotoxicological Models under Uncertainty
Klein, Judith
: Schultz, Rüdiger; Escudero, Laureano F.; Schäfers, Christoph
Dissertation
2018Anti-inflammatory nitro-fatty acids suppress tumor growth by triggering mitochondrial dysfunction and activation of the intrinsic apoptotic pathway in colorectal cancer cells
Kühn, B.; Brat, C.; Fettel, J.; Hellmuth, N.; Maucher, I.V.; Bulut, I.; Hock, K.J.; Grimmer, J.; Manolikakes, G.; Rühl, M.; Kühn, A.; Zacharowski, K.; Matrone, C.; Urbschat, A.; Roos, J.; Steinhilber, D.; Maier, T.J.
Zeitschriftenaufsatz
2018Antiplasmodial activity of tick defensins in a mouse model of malaria
Couto, J.; Tonk, M.; Ferrolho, J.; Antunes, S.; Vilcinskas, A.; Fuente, J. de la; Domingos, A.; Cabezas-Cruz, A.
Zeitschriftenaufsatz
2018Apoptotic Cancer Cells Suppress 5-Lipoxygenase in Tumor-Associated Macrophages
Ringleb, J.; Strack, E.; Angioni, C.; Geisslinger, G.; Steinhilber, D.; Weigert, A.; Brüne, B.
Zeitschriftenaufsatz
2018Artificial neural network-assisted spectrophotometric method for monitoring fructo-oligosaccharides production
Erdős, B.; Grachten, M.; Czermak, P.; Kovács, Z.
Zeitschriftenaufsatz
2018Aryl thiosemicarbazones for the treatment of trypanosomatidic infections
Linciano, P.; Moraes, C.B.; Alcantara, L.M.; Franco, C.H.; Pascoalino, B.; Freitas-Junior, L.H.; Macedo, S.; Santarem, N.; Cordeiro-da-Silva, A.; Gul, S.; Witt, G.; Kuzikov, M.; Ellinger, B.; Ferrari, S.; Luciani, R.; Quotadamo, A.; Costantino, L.; Costi, M.P.
Zeitschriftenaufsatz
2018Aspergillus-specific antibodies: Targets and applications
Schubert, M.; Spiegel, H.; Schillberg, S.; Nölke, G.
Zeitschriftenaufsatz
2018Assessment of seafood contamination under the marine strategy framework directive: Contributions of the German environmental specimen bank
Fliedner, Annette; Rüdel, Heinz; Knopf, Burkhard; Lohmann, Nina; Paulus, Martin; Jud, Michael; Pirntke, Ulrike; Koschorreck, Jan
Zeitschriftenaufsatz
2018Astrocytic ATX fuels synaptic phospholipid signaling involved in psychiatric disorders
Thalman, C.; Horta, G.; Qiao, L.; Endle, H.; Tegeder, I.; Cheng, H.; Laube, G.; Sigrudsson, T.; Hauser, M.J.; Tenzer, S.; Distler, U.; Aoki, J.; Morris, A.J.; Geisslinger, G.; Röper, J.; Kirischuk, S.; Luhmann, H.J.; Radyushkin, K.; Nitsch, R.; Vogt, J.
Zeitschriftenaufsatz
2018Biomarker und Bildgebung zur Diagnose und Stratifizierung der rheumatoiden Arthritis und Spondylarthritis im BMBF-Verbund ArthroMark
Häupl, T.; Skapenko, A.; Hoppe, B.; Skriner, K.; Burkhardt, H.; Poddubnyy, D.; Ohrndorf, S.; Sewerin, P.; Mansmann, U.; Stuhlmüller, B.; Schulze-Koops, H.; Burmester, G.-R.
Zeitschriftenaufsatz
2018Bioreactor-based production of glycoproteins in plant cell suspension cultures
Holland, T.; Buyel, J.F.
Aufsatz in Buch
2018Biota monitoring under the Water Framework Directive: On tissue choice and fish species selection
Fliedner, Annette; Rüdel, Heinz; Lohmann, Nina; Buchmeier, Georgia; Koschorreck, Jan
Zeitschriftenaufsatz
2018Boosting Anti-Inflammatory Potency of Zafirlukast by Designed Polypharmacology
Schierle, S.; Flauaus, C.; Heitel, P.; Willems, S.; Schmidt, J.; Kaiser, A.; Weizel, L.; Goebel, T.; Kahnt, A.S.; Geisslinger, G.; Steinhilber, D.; Wurglics, M.; Rovati, G.E.; Schmidtko, A.; Proschak, E.; Merk, D.
Zeitschriftenaufsatz
2018Bovine embryo elongation is altered due to maternal fatty acid supplementation
Giller, K.; Drews, B.; Berard, J.; Kienberger, H.; Schmicke, M.; Frank, J.; Spanier, B.; Daniel, H.; Geisslinger, G.; Ulbrich, S.E.
Zeitschriftenaufsatz
2018C5aR activation in the absence of C5a
Syed, S.N.; Rau, E.; Ziegelmann, M.; Sogkas, G.; Brüne, B.; Schmidt, R.E.
Zeitschriftenaufsatz
2018Cationic polyacrylamide copolymers (PAMs): Environmental half life determination in sludge‑treated soil
Hennecke, Dieter; Bauer, Angela; Herrchen, Monika; Wischerhoff, Erik; Gores, Friedhelm
Zeitschriftenaufsatz
2018Cell adhesion-induced transient interaction of ADAM15 with poly(A) binding protein at the cell membrane colocalizes with mRNA translation
Böhm, B.B.; Fehrl, Y.; Janczi, T.; Schneider, N.; Burkhardt, H.
Zeitschriftenaufsatz
2018Cell-free protein synthesis system
Buntru, Matthias; Schillberg, Stefan; Vogel, Simon
Patent
2018Challenges in the Development of a Thiol-Based Broad-Spectrum Inhibitor for Metallo-β-Lactamases
Büttner, D.; Kramer, J.S.; Klingler, F.-M.; Wittmann, S.K.; Hartmann, M.R.; Kurz, C.G.; Kohnhäuser, D.; Weizel, L.; Brüggerhoff, A.; Frank, D.; Steinhilber, D.; Wichelhaus, T.A.; Pogoryelov, D.; Proschak, E.
Zeitschriftenaufsatz
2018Characterization of new anti-IL-6 antibodies revealed high potency candidates for intracellular cytokine detection and specific targeting of IL-6 receptor binding sites
Chouman, Karinna; Korioth-Schmitz, Birgit; Sack, Markus; Engelbert Schmitz, Jörn; Tuan Pham, Anh; Fischer, Rainer; Barth, Stefan; Klockenbring, Torsten; Fendel, Rolf
Zeitschriftenaufsatz
2018Chemosensitivity of human colon cancer cells is influenced by a p53-dependent enhancement of ceramide synthase 5 and induction of autophagy
Brachtendorf, S.; Wanger, R.A.; Birod, K.; Thomas, D.; Trautmann, S.; Wegner, M.-S.; Fuhrmann, D.C.; Brüne, B.; Geisslinger, G.; Grösch, S.
Zeitschriftenaufsatz
2018Combined Proteomic and In Silico Target Identification Reveal a Role for 5-Lipoxygenase in Developmental Signaling Pathways
Brand, S.; Roy, S.; Schröder, P.; Rathmer, B.; Roos, J.; Kapoor, S.; Patil, S.; Pommerenke, C.; Maier, T.; Janning, P.; Eberth, S.; Steinhilber, D.; Schade, D.; Schneider, G.; Kumar, K.; Ziegler, S.; Waldmann, H.
Zeitschriftenaufsatz
2018Comparative analysis of the transcriptome responses of zebrafish embryos after exposure to low concentrations of cadmium, cobalt and copper
Sonnack, Laura; Klawonn, Thorsten; Kriehuber, Ralf; Hollert, Henner; Schäfers, Christoph; Fenske, Martina
Zeitschriftenaufsatz
2018Comparative estrogenicity of endogenous, environmental and dietary estrogens in pregnant women I
Fleck, S.C.; Twaddle, N.C.; Churchwell, M.I.; Doerge, D.R.; Pande, P.; Teeguarden, J.G.
Zeitschriftenaufsatz
2018A comparison of two biorelevant in vitro drug release methods for nanotherapeutics based on advanced physiologically-based pharmacokinetic modelling
Jung, F.; Nothnagel, L.; Gao, F.; Thurn, M.; Vogel, V.; Wacker, M.G.
Zeitschriftenaufsatz
2018Computational functional genomics-based approaches in analgesic drug discovery and repurposing
Lippmann, C.; Kringel, D.; Ultsch, A.; Lötsch, J.
Zeitschriftenaufsatz
2018A coupled fluorescence-based assay for the detection of protein arginine N-methyltransferase 6 (PRMT6) enzymatic activity
Kramer, J.; Désor, V.; Brunst, S.; Wittmann, S.K.; Lausen, J.; Heering, J.; Proschak, A.; Proschak, E.
Zeitschriftenaufsatz
2018Current evidence of cannabinoid-based analgesia obtained in preclinical and human experimental settings
Lötsch, J.; Weyer-Menkhoff, I.; Tegeder, I.
Zeitschriftenaufsatz
2018Current status and perspectives of the molecular farming landscape
Spiegel, H.; Stöger, E.; Twyman, R.M.; Buyel, J.F.
Aufsatz in Buch
2018Decreasing δ13C and δ15N values in four coastal species at different trophic levels indicate a fundamental food-web shift in the southern North and Baltic Seas between 1988 and 2016
Corman, Anna-Marie; Schwemmer, Philipp; Mercker, Moritz; Asmus, Harald; Rüdel, Heinz; Klein, Roland; Boner, Markus; Hofem, Sabine; Koschorreck, Jan; Garthe, Stefan
Zeitschriftenaufsatz
2018Development of a Focused Library of Triazole‐Linked Privileged‐Structure‐Based Conjugates Leading to the Discovery of Novel Phenotypic Hits against Protozoan Parasitic Infections
Uliassi, E.; Piazzi, L.; Belluti, F.; Mazzanti, A.; Kaiser, M.; Brun, R.; Moraes, C.B.; Freitas-Junior, L.H.; Gul, S.; Kuzikov, M.; Ellinger, B.; Borsari, C.; Costi, M.P.; Bolognesi, M.L.
Zeitschriftenaufsatz
2018Development, current applications and future roles of biorelevant two‐stage in vitro testing in drug development
Fiolka, T.; Dressman, J.
Zeitschriftenaufsatz
2018Dielectric Spectroscopy and Optical Density Measurement for the Online Monitoring and Control of Recombinant Protein Production in Stably Transformed Drosophila melanogaster S2 Cells
Zitzmann, J.; Weidner, T.; Eichner, G.; Salzig, D.; Czermak, P.
Zeitschriftenaufsatz
2018Dietary phytol reduces clinical symptoms in experimental autoimmune encephalomyelitis (EAE) at least partially by modulating NOX2 expression
Blum, L.; Tafferner, N.; Spring, I.; Kurz, J.; deBruin, N.; Geisslinger, G.; Parnham, M.J.; Schiffmann, S.
Zeitschriftenaufsatz
2018Differentiation of human iPSCs into VSMCs and generation of VSMC-derived calcifying vascular cells
Trillhaase, A.; Haferkamp, U.; Rangnau, A.; Märtens, M.; Schmidt, B.; Trilck, M.; Seibler, P.; Aherrahrou, R.; Erdmann, J.; Aherrahrou, Z.
Zeitschriftenaufsatz
2018Dimerization quality control via ubiquitylation
Herhaus, L.; Dikic, I.
Zeitschriftenaufsatz
2018Discovery of polar spirocyclic orally bioavailable urea inhibitors of soluble epoxide hydrolase
Lukin, A.; Kramer, J.; Hartmann, M.; Weizel, L.; Hernandez-Olmos, V.; Falahati, K.; Burghardt, I.; Kalinchenkova, N.; Bagnyukova, D.; Zhurilo, N.; Rautio, J.; Forsberg, M.; Ihalainen, J.; Auriola, S.; Leppänen, J.; Konstantinov, I.; Pogoryelov, D.; Proschak, E.; Dar'in, D.; Krasavin, M.
Zeitschriftenaufsatz
2018Downregulation of BTLA on NKT Cells Promotes Tumor Immune Control in a Mouse Model of Mammary Carcinoma
Sekar, D.; Govene, L.; Del Río, M.-L.; Sirait-Fischer, E.; Fink, A.F.; Brüne, B.; Rodriguez-Barbosa, J.I.; Weigert, A.
Zeitschriftenaufsatz
2018Downstream processing of a plant-derived malaria transmission-blocking vaccine candidate
Menzel, S.; Holland, T.; Boes, A.; Spiegel, H.; Fischer, R.; Buyel, J.F.
Zeitschriftenaufsatz
2018Drug-Mediated Intracellular Donation of Nitric Oxide Potently Inhibits 5-Lipoxygenase
Roos, J.; Peters, M.; Maucher, I.V.; Kühn, B.; Fettel, J.; Hellmuth, N.; Brat, C.; Sommer, B.; Urbschat, A.; Piesche, M.; Vogel, A.; Proschak, E.; Blöcher, R.; Buscató, E.; Häfner, A.-K.; Matrone, C.; Werz, O.; Heidler, J.; Wittig, I.; Angioni, C.; Geisslinger, G.; Parnham, M.J.; Zacharowski, K.; Steinhilber, D.; Maier, T.J.
Zeitschriftenaufsatz
2018Efficacy and safety of tregalizumab in patients with rheumatoid arthritis and an inadequate response to methotrexate
Vollenhoven, R.F. van; Keystone, E.C.; Strand, V.; Pacheco-Tena, C.; Vencovský, J.; Behrens, F.; Racewicz, A.; Zipp, D.; Rharbaoui, F.; Wolter, R.; Knierim, L.; Schmeidl, R.; Zhou, X.; Aigner, S.; Dälken, B.; Wartenberg-Demand, A.
Zeitschriftenaufsatz
2018Elimination of different leukaemia subtypes using novel CD89-specific human cytolytic fusion proteins
Gresch, G.; Schenke, L.; Mladenov, R.; Zwirner, S.; Cremer, C.; Niesen, J.; Grieger, E.; Brümmendorf, T.; Jost, E.; Fischer, R.; Stockmeyer, B.; Barth, S.; Nachreiner, T.; Stein, C.
Zeitschriftenaufsatz
2018Elusive mitochondrial connection to inflammation uncovered
Stolz, A.; Dikic, I.
Zeitschriftenaufsatz
2018Empfehlung zur Einrichtung eines nationalen Observatorien-Netzes für die terrestrische Ökosystemforschung
Kögel-Knabner, Ingrid; Teutsch, Georg; Adrian, Rita; Blanckenburg, Friedhelm von; Flügge, Ulf-Ingo; Kolle, Olaf; Kleinn, Christoph; Küsel, Kirsten; Lischeid, Gunnar; Löw, Alexander; Schäfers, Christoph; Schmid, Hans Peter; Simmer, Clemens; Vereecken, Harry; Walz, Rainer
Bericht
2018Environmental impacts by fragments released from nanoenabled products: A multiassay, multimaterial exploration by the SUN approach
Amorim, Monica J.B.; Lin, Sijie; Schlich, Karsten; Navas, Jose Maria; Brunelli, Andrea; Neubauer, Nicole; Vilsmeier, Klaus; Costa, Anna L.; Gondikas, Andreas; Xia, Tian; Galbis, Liliana; Badetti, Elena; Marcomini, Antonio; Hristozov, Danail; Kammer, Frank von der; Hund-Rinke, Kerstin; Scott-Fordsmand, Janeck J.; Nel, André; Wohlleben, Wendel
Zeitschriftenaufsatz
2018Enzyme membrane reactor system (EMRS) for the bioconversion of lignin-containing substrates by a novel heme peroxidase
Busse, N.
Dissertation
2018Expression and purification of human phosphatase and actin regulator 1 (PHACTR1) in plant-based systems
Gengenbach, B.B.; Müschen, C.R.; Buyel, J.F.
Zeitschriftenaufsatz
2018Fishing for contaminants
Hausen, J.; Otte, J.C.; Legradi, J.; Yang, L.; Strähle, U.; Fenske, M.; Hecker, M.; Tang, S.; Hammers-Wirtz, M.; Hollert, H.; Keiter, S.H.; Ottermanns, R.
Zeitschriftenaufsatz
2018Fitness costs of infection with Serratia symbiotica are associated with greater susceptibility to insecticides in the pea aphid Acyrthosiphon pisum
Skaljac, M.; Kirfel, P.; Grotmann, J.; Vilcinskas, A.
Zeitschriftenaufsatz
2018Four chemical trends will shape the next decade's directions in perfluoroalkyl and polyfluoroalkyl substances research
Kotthoff, Matthias; Bücking, Mark
Zeitschriftenaufsatz
2018Fraunhofer-Institut für Molekularbiologie und Angewandte Oekologie. Jahresbericht 2017/2018
 
Jahresbericht
2018A freshwater mesocosm study into the effects of the neonicotinoid insecticide thiamethoxam at multiple trophic levels
Finnegan, Meaghean C.; Emburey, Simon; Hommen, Udo; Baxter, Leilan R.; Hoekstra, Paul F.; Hanson, Mark L.; Thompson, Helen; Hamer, Mick
Zeitschriftenaufsatz
2018The FT/FD-dependent initiation of flowering under long-day conditions in the day-neutral species Nicotiana tabacum originates from the facultative short-day ancestor Nicotiana tomentosiformis
Beinecke, F.A.; Grundmann, L.; Wiedmann, D.R.; Schmidt, F.J.; Caesar, A.S.; Zimmermann, M.; Lahme, M.; Twyman, R.M.; Prüfer, D.; Noll, G.A.
Zeitschriftenaufsatz
2018Functional exploration of natural networks and ecological communities
Ankenbrand, M.J.; Hohlfeld, S.C.Y.; Weber, L.; Förster, F.; Keller, A.
Zeitschriftenaufsatz
2018Gene silencing in Tribolium castaneum as a tool for the targeted identification of candidate RNAi targets in crop pests
Knorr, E.; Fishilevich, E.; Tenbusch, L.; Frey, M.L.F.; Rangasamy, M.; Billion, A.; Worden, S.E.; Gandra, P.; Arora, K.; Lo, W.; Schulenberg, G.; Valverde-Garcia, P.; Vilcinskas, A.; Narva, K.E.
Zeitschriftenaufsatz
2018The genome sequence of the commercially cultivated mushroom Agrocybe aegerita reveals a conserved repertoire of fruiting-related genes and a versatile suite of biopolymer-degrading enzymes
Gupta, D.K.; Rühl, M.; Mishra, B.; Kleofas, V.; Hofrichter, M.; Herzog, R.; Pecyna, M.J.; Sharma, R.; Kellner, H.; Hennicke, F.; Thines, M.
Zeitschriftenaufsatz
2018Grouping concept for metal and metal oxide nanomaterials with regard to their ecotoxicological effects on algae, daphnids and fish embryos
Hund-Rinke, K.; Schlich, Karsten; Kühnel, Dana; Hellack, Bryan; Kaminski, Heinz; Nickel, Carmen
Zeitschriftenaufsatz
2018Halogenated flame retardants in tree samples applied as bioindicatorsfor atmospheric pollution
Dreyer, Annekatrin; Neugebauer, Frank; Rüdel, Heinz; Klein, Roland; Lohmann, Nina; Rauert, Caren; Koschorreck, Jan
Zeitschriftenaufsatz
2018Heterotypic Ubiquitin Chains: Seeing is Believing
Stolz, A.; Dikic, I.
Zeitschriftenaufsatz
2018High cell density cultivation of Δgor/ΔtrxB E. coli in a chemically defined minimal medium with an enhanced iron concentration
Joachim, M.; Schäfer, J.G.; Gerlach, D.; Czermak, P.
Zeitschriftenaufsatz
2018High titer oncolytic measles virus production process by integration of dielectric spectroscopy as online monitoring system
Grein, T.A.; Loewe, D.; Dieken, H.; Salzig, D.; Weidner, T.; Czermak, P.
Zeitschriftenaufsatz
2018High-sensitive troponin is associated with subclinical imaging biosignature of inflammatory cardiovascular involvement in systemic lupus erythematosus
Winau, L.; Baydes, R.H.; Braner, A.; Drott, U.; Burkhardt, H.; Sangle, S.; D'Cruz, D.P.; Carr-White, G.; Marber, M.; Schnoes, K.; Arendt, C.; Klingel, K.; Vogl, T.J.; Zeiher, A.M.; Nagel, E.; Puntmann, V.O.
Zeitschriftenaufsatz
2018Highly efficient genome editing by homology-directed repair using Cas9 protein in Ceratitis capitata
Aumann, R.A.; Schetelig, M.F.; Häcker, I.
Zeitschriftenaufsatz
2018How to effectively treat acute leukemia patients bearing MLL-rearrangements?
Steinhilber, D.; Marschalek, R.
Zeitschriftenaufsatz
2018How to measure release from nanosized carriers?
Nothnagel, L.; Wacker, M.G.
Zeitschriftenaufsatz
2018Human pharmacological approaches to TRP-ion-channel-based analgesic drug development
Weyer-Menkhoff, I.; Lötsch, J.
Zeitschriftenaufsatz
2018Identification and characterization of natural viruses associated with the invasive insect pest Drosophila suzukii
Carrau, T.; Hiebert, N.; Vilcinskas, A.; Lee, K.-Z.
Zeitschriftenaufsatz
2018Identification of approved drugs as potent inhibitors of pregnane X receptor activation with differential receptor interaction profiles
Burk, O.; Kuzikov, M.; Kronenberger, T.; Jeske, J.; Keminer, O.; Thasler, W.E.; Schwab, M.; Wrenger, C.; Windshügel, B.
Zeitschriftenaufsatz
2018Immunological larval polyphenism in the map butterfly Araschnia levana reveals the photoperiodic modulation of immunity
Baudach, A.; Lee, K.-Z.; Vogel, H.; Vilcinskas, A.
Zeitschriftenaufsatz
2018An in silico approach to determine challenges in the bioavailability of ciprofloxacin, a poorly soluble weak base with borderline solubility and permeability characteristics
Hansmann, S.; Miyaji, Y.; Dressman, J.
Zeitschriftenaufsatz
2018In vitro and in silico analysis of the effects of D2 receptor antagonist target binding kinetics on the cellular response to fluctuating dopamine concentrations
Witte, W.E.A. de; Versfelt, J.W.; Kuzikov, M.; Rolland, S.; Georgi, V.; Gribbon, P.; Gul, S.; Huntjens, D.; Graaf, P.H. van der; Danhof, M.; Fernández‐Montalván, A.; Witt, G.; Lange, E.C.M. de
Zeitschriftenaufsatz
2018An in vitro test system for compounds that modulate human inflammatory macrophage polarization
Shiratori, H.; Feinweber, C.; Luckhardt, S.; Wallner, N.; Geisslinger, G.; Weigert, A.; Parnham, M.J.
Zeitschriftenaufsatz
2018Inactivation kinetics of Escherichia Coli and Staphylococcus Aureus by a hydrogen peroxide based disinfectant
Grigoryan, K.; Badalyan, G.; Nersisyan, L.; Tavadyan, L.; Sargsyan, M.
Zeitschriftenaufsatz
2018Inhibition of 53BP1 favors homology-dependent DNA repair and increases CRISPR-Cas9 genome-editing efficiency
Canny, M.D.; Moatti, N.; Wan, L.C.K.; Fradet-Turcotte, A.; Krasner, D.; Mateos-Gomez, P.A.; Zimmermann, M.; Orthwein, A.; Juang, Y.-C.; Zhang, W.; Noordermeer, S.M.; Seclen, E.; Wilson, M.D.; Vorobyov, A.; Munro, M.; Ernst, A.; Ng, T.F.; Cho, T.; Cannon, P.M.; Sidhu, S.S.; Sicheri, F.; Durocher, D.
Zeitschriftenaufsatz
2018Insights into catalysis and function of phosphoribosyl-linked serine ubiquitination
Kalayil, S.; Bhogaraju, S.; Bonn, F.; Shin, D.; Liu, Y.; Gan, N.; Basquin, J.; Grumati, P.; Luo, Z.-Q.; Dikic, I.
Zeitschriftenaufsatz
2018Ixekizumab is efficacious when used alone or when added to conventional synthetic disease-modifying antirheumatic drugs (cDMARDs) in patients with active psoriatic arthritis and previous inadequate response or intolerance to tumour necrosis factor inhibitors
Nash, P.; Behrens, F.; Orbai, A.-M.; Rathmann, S.S.; Adams, D.H.; Benichou, O.; Deodhar, A.
Zeitschriftenaufsatz
2018Knotting nets. Molecular junctions of interconnecting endocrine axes identified by application of the adverse outcome pathway (AOP) concept
Brüggemann, Maria; Licht, Oliver; Fetter, Éva; Teigeler, Matthias; Schäfers, Christoph; Eilebrecht, Elke
Zeitschriftenaufsatz
2018The levels of peroxisomal catalase protein and activity modulate the onset of cell death in tobacco BY-2 cells via reactive oxygen species levels and autophagy
Tyutereva, Elena V.; Dobryakova, Ksenia S.; Schiermeyer, Andreas; Shishova, Maria F.; Pawlowski, Katharina; Demidchik, Vadim; Reumann, Sigrun; Voitsekhovskaja, Olga V.
Zeitschriftenaufsatz
2018A linear epitope coupled to DsRed provides an affinity ligand for the capture of monoclonal antibodies
Rühl, C.; Knödler, M.; Opdensteinen, P.; Buyel, J.F.
Zeitschriftenaufsatz
2018Long-term effects of three different silver sulfide nanomaterials, silver nitrate and bulk silver sulfide on soil microorganisms and plants
Schlich, Karsten; Hoppe, Martin; Kraas, Marco; Schubert, Jonas; Chanana, Munish; Hund-Rinke, Kerstin
Zeitschriftenaufsatz
2018Low protease content in Medicago truncatula cell cultures facilitates recombinant protein production
Santos, Rita B.; Chandrasekar, Balakumaran; Mandal, Manoj K.; Kaschani, Farnush; Kaiser, Markus; Both, Leonard; Hoorn, Renier A.L. van der; Schiermeyer, Andreas; Abranches, Rita
Zeitschriftenaufsatz
2018Machine learning in pain research
Lötsch, J.; Ultsch, A.
Zeitschriftenaufsatz
2018A machine-learned analysis of human gene polymorphisms modulating persisting pain points to major roles of neuroimmune processes
Kringel, D.; Lippmann, C.; Parnham, M.J.; Kalso, E.; Ultsch, A.; Lötsch, J.
Zeitschriftenaufsatz
2018Machine-learned analysis of quantitative sensory testing responses to noxious cold stimulation in healthy subjects
Weyer-Menkhoff, I.; Thrun, M.C.; Lötsch, J.
Zeitschriftenaufsatz
2018Machine-learned selection of psychological questionnaire items relevant to the development of persistent pain after breast cancer surgery
Lötsch, J.; Sipilä, R.; Dimova, V.; Kalso, E.
Zeitschriftenaufsatz
2018Machine-learning based lipid mediator serum concentration patterns allow identification of multiple sclerosis patients with high accuracy
Lötsch, J.; Schiffmann, S.; Schmitz, K.; Brunkhorst, R.; Lerch, F.; Ferreiros, N.; Wicker, S.; Tegeder, I.; Geisslinger, G.; Ultsch, A.
Zeitschriftenaufsatz
2018Machine-learning-derived classifier predicts absence of persistent pain after breast cancer surgery with high accuracy
Lötsch, J.; Sipilä, R.; Tasmuth, T.; Kringel, D.; Estlander, A.-M.; Meretoja, T.; Kalso, E.; Ultsch, A.
Zeitschriftenaufsatz
2018Mannan-induced Nos2 in macrophages enhances IL-17–driven psoriatic arthritis by innate lymphocytes
Zhong, J.; Scholz, T.; Yau, A.C.Y.; Guerard, S.; Hüffmeier, U.; Burkhardt, H.; Holmdahl, R.
Zeitschriftenaufsatz
2018Manufacturing and Safety Guidelines for Manufactured Functionalized Nanomaterials in Pharmaceutics
Wacker, M.G.; Janas, C.; Ferreira, F.S.; Vieira, F.P.
Aufsatz in Buch
2018Mechanism and medical implications of mammalian autophagy
Dikic, I.; Elazar, Z.
Zeitschriftenaufsatz
2018Metabolomic Profiles for Primary Progressive Multiple Sclerosis Stratification and Disease Course Monitoring
Stoessel, D.; Stellmann, J.-P.; Willing, A.; Behrens, B.; Rosenkranz, S.C.; Hodecker, S.C.; Stürner, K.H.; Reinhardt, S.; Fleischer, S.; Deuschle, C.; Maetzler, W.; Berg, D.; Heesen, C.; Walther, D.; Schauer, N.; Friese, M.A.; Pless, O.
Zeitschriftenaufsatz
2018Mitochondrial fragmentation in human macrophages attenuates palmitate-induced inflammatory responses
Zezina, E.; Snodgrass, R.G.; Schreiber, Y.; Zukunft, S.; Schürmann, C.; Meyer zu Heringdorff, D.; Geisslinger, G.; Fleming, I.; Brandes, R.P.; Brüne, B.; Namgaladze, D.
Zeitschriftenaufsatz
2018Molecular techniques for the detection and identification of yeasts in wine
Diaz, Cecilia; Badalyan, Grigori; Bücking, Mark
Aufsatz in Buch
2018Mutations in PMPCB Encoding the Catalytic Subunit of the Mitochondrial Presequence Protease Cause Neurodegeneration in Early Childhood
Vögtle, F.-N.; Brändl, B.; Larson, A.; Pendziwiat, M.; Friederich, M.W.; White, S.M.; Basinger, A.; Kücükköse, C.; Muhle, H.; Jähn, J.A.; Keminer, O.; Helbig, K.L.; Delto, C.F.; Myketin, L.; Mossmann, D.; Burger, N.; Miyake, N.; Burnett, A.; Baalen, A. van; Lovell, M.A.; Matsumoto, N.; Walsh, M.; Yu, H.-C.; Shinde, D.N.; Stephani, U.; Hove, J.L.K. van; Müller, F.-J.; Helbig, I.
Zeitschriftenaufsatz
2018Mutual inversion of flurbiprofen enantiomers in various rat and mouse strains
Bruin, N. de; Ferreirós, N.; Schmidt, M.; Hofmann, M.; Angioni, C.; Geisslinger, G.; Parnham, M.J.
Zeitschriftenaufsatz
2018Nanomaterials: Certain aspects of application, risk assessment and risk communication
Laux, Peter; Tentschert, Jutta; Riebeling, Christian; Braeuning, Albert; Creutzenberg, Otto; Epp, Astrid; Fessard, Valérie; Haas, Karl-Heinz; Haase, Andrea; Hund-Rinke, Kerstin; Jakubowski, Norbert; Kearns, Peter; Lampen, Alfonso; Rauscher, Hubert; Schoonjans, Reinhilde; Störmer, Angela; Thielmann, Axel; Mühle, Uwe; Luch, Andreas
Zeitschriftenaufsatz
2018Nanopharmaceuticals for wound healing
Ashtikar, M.; Wacker, M.G.
Zeitschriftenaufsatz
2018Non-invasive bioluminescence imaging as a standardized assessment measure in mouse models of dermal inflammation
Hofmann, M.C.J.; Schmidt, M.; Arne, O.; Geisslinger, G.; Parnham, M.J.; Bruin, N.M.W.J. de
Zeitschriftenaufsatz
2018Novel sensor platform for rapid detection and quantification of coliforms on food contact surfaces
Badalyan, Grigori; Diaz, Cecilia; Bücking, Mark; Lipski, André
Zeitschriftenaufsatz
2018Nutritional immunology: Diversification and diet-dependent expression of antimicrobial peptides in the black soldier fly Hermetia illucens
Vogel, H.; Müller, A.; Heckel, D.G.; Gutzeit, H.; Vilcinskas, A.
Zeitschriftenaufsatz
2018On the relationship of anthranilic derivatives structure and the FXR (Farnesoid X receptor) agonist activity
Kronenberger, T.; Windshügel, B.; Wrenger, C.; Honorio, K.M.; Maltarollo, V.G.
Zeitschriftenaufsatz
2018Optimizing the composition of a synthetic cellulosome complex for the hydrolysis of softwood pulp
Leis, B.; Held, C.; Andreeßen, B.; Liebl, W.; Graubner, S.; Schulte, L.-P.; Schwarz, W.H.; Zverlov, V.V.
Zeitschriftenaufsatz
2018Oral plasma kallikrein inhibitor for prophylaxis in hereditary angioedema
Aygören-Pürsün, E.; Bygum, A.; Grivcheva-Panovska, V.; Magerl, M.; Graff, J.; Steiner, U.C.; Fain, O.; Huissoon, A.; Kinaciyan, T.; Farkas, H.; Lleonart, R.; Longhurst, H.J.; Rae, W.; Triggiani, M.; Aberer, W.; Cancian, M.; Zanichelli, A.; Smith, W.B.; Baeza, M.L.; Du-Thanh, A.; Gompels, M.; Gonzalez-Quevedo, T.; Greve, J.; Guilarte, M.; Katelaris, C.; Dobo, S.; Cornpropst, M.; Clemons, D.; Fang, L.; Collis, P.; Sheridan, W.; Maurer, M.; Cicardi, M.
Zeitschriftenaufsatz
2018The oxidized linoleic acid metabolite 12,13-DiHOME mediates thermal hyperalgesia during inflammatory pain
Zimmer, B.; Angioni, C.; Osthues, T.; Toewe, A.; Thomas, D.; Pierre, S.C.; Geisslinger, G.; Scholich, K.; Sisignano, M.
Zeitschriftenaufsatz
2018Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells
Hitzel, J.; Lee, E.; Zhang, Y.; Bibli, S.I.; Li, X.; Zukunft, S.; Pflüger, B.; Hu, J.; Schürmann, C.; Vasconez, A.E.; Oo, J.A.; Kratzer, A.; Kumar, S.; Rezende, F.; Josipovic, I.; Thomas, D.; Giral, H.; Schreiber, Y.; Geisslinger, G.; Fork, C.; Yang, X.; Sigala, F.; Romanoski, C.E.; Kroll, J.; Jo, H.; Landmesser, U.; Lusis, A.J.; Namgaladze, D.; Fleming, I.; Leisegang, M.S.; Zhu, J.; Brandes, R.P.
Zeitschriftenaufsatz
2018Physical behavior and sampling of airborne particles
Hochrainer, D.
Aufsatz in Buch
2018Plants as sources of natural and recombinant anti-cancer agents
Buyel, J.F.
Zeitschriftenaufsatz
2018Population-specific expression of antimicrobial peptides conferring pathogen resistance in the invasive ladybird Harmonia axyridis
Gegner, T.; Schmidtberg, H.; Vogel, H.; Vilcinskas, A.
Zeitschriftenaufsatz
2018The portal vein as a distinct immunological compartment
Queck, A.; Rueschenbaum, S.; Kubesch, A.; Cai, C.; Zeuzem, S.; Weigert, A.; Brüne, B.; Nour-Eldin, A.; Gruber-Rouh, T.; Vogl, T.; Lange, C.M.
Zeitschriftenaufsatz
2018Primary fish hepatocytes as in vitro test system to study the metabolism of xenobiotics in fish
Bischof, Ina
: Segner, Helmut; Schlechtriem, Christian
Dissertation
2018Promoter construct for cell-free protein synthesis
Buntru, Matthias; Schillberg, Stefan; Vogel, Simon
Patent
2018The prostaglandin E2 receptor EP3 controls CC-chemokine ligand 2–mediated neuropathic pain induced by mechanical nerve damage
Treutlein, E.-M.; Kern, K.; Weigert, A.; Tarighi, N.; Schuh, C.-D.; Nüsing, R.M.; Schreiber, Y.; Ferreirós, N.; Brüne, B.; Geisslinger, G.; Pierre, S.; Scholich, K.
Zeitschriftenaufsatz
2018Proteomic analysis of CHO cell lines producing high and low quantities of a recombinant antibody before and after selection with methotrexate
Hausmann, R.; Chudobová, I.; Spiegel, H.; Schillberg, S.
Zeitschriftenaufsatz
2018Redox-signals and macrophage biology
Weigert, A.; Knethen, A. von; Fuhrmann, D.; Dehne, N.; Brüne, B.
Zeitschriftenaufsatz
2018A reference genome of the Chinese hamster based on a hybrid assembly strategy
Rupp, O.; MacDonald, M.L.; Li, S.; Dhiman, H.; Polson, S.; Griep, S.; Heffner, K.; Hernandez, I.; Brinkrolf, K.; Jadhav, V.; Samoudi, M.; Hao, H.; Kingham, B.; Goesmann, A.; Betenbaugh, M.J.; Lewis, N.E.; Borth, N.; Lee, K.H.
Zeitschriftenaufsatz
2018The relevance of ceramides and their synthesizing enzymes for multiple sclerosis
Kurz, J.; Brunkhorst, R.; Foerch, C.; Blum, L.; Henke, M.; Gabriel, L.; Ulshöfer, T.; Ferreiros, N.; Parnham, M.J.; Geisslinger, G.; Schiffmann, S.
Zeitschriftenaufsatz
2018Reliability of In Vitro Methods Used to Measure Intrinsic Clearance of Hydrophobic Organic Chemicals by Rainbow Trout
Nichols, John; Fay, Kellie; Bernhard, Mary Jo; Bischof, Ina; Davis, John; Halder, Marlies; Hu, Jing; Johanning, Karla; Laue, Heike; Nabb, Diane; Schlechtriem, Christian; Segner, Helmut; Swintek, Joe; Weeks, John; Embry, Michelle
Zeitschriftenaufsatz
2018Reliable high-density energy storage in Si-doped HfO2 thin films on 3D-structures
Kühnel, Kati; Riedel, Stefan; Mart, Clemens; Weinreich, Wenke
Vortrag
2018Response of the Mayfly (Cloeon Dipterum) to chronic exposure to Thiamethoxam in outdoor Mesocosms
Pickford, Daniel B.; Finnegan, Meaghean C.; Baxter, Leilan R.; Böhmer, Walter; Hanson, Mark L.; Stegger, Petra; Hommen, Udo; Hoekstra, Paul F.; Hamer, Mick
Zeitschriftenaufsatz
2018Revisiting elimination half live as an indicator for bioaccumulation in fish and terrestrial mammals
Goss, Kai-Uwe; Linden, Lukas; Ulrich, Nadin; Schlechtriem, Christian
Zeitschriftenaufsatz
2018S2e-Leitlinie: Therapie der rheumatoiden Arthritis mit krankheitsmodifizierenden Medikamenten
Fiehn, C.; Holle, J.; Iking-Konert, C.; Leipe, J.; Weseloh, C.; Frerix, M.; Alten, R.; Behrens, F.; Baerwald, C.; Braun, J.; Burkhardt, H.; Burmester, G.; Detert, J.; Gaubitz, M.; Gause, A.; Gromnica-Ihle, E.; Kellner, H.; Krause, A.; Kuipers, J.; Lorenz, H.-M.; Müller-Ladner, U.; Nothacker, M.; Nüsslein, H.; Rubbert-Roth, A.; Schneider, M.; Schulze-Koops, H.; Seitz, S.; Sitter, H.; Specker, C.; Tony, H.-P.; Wassenberg, S.; Wollenhaupt, J.; Krüger, K.
Zeitschriftenaufsatz
2018Scientific Opinion about the Guidance of the Chemical Regulation Directorate (UK) on how aged sorption studies for pesticides should be conducted, analysed and used in regulatory assessments
Ockleford, Colin; Hernandez-Jerez, Antonio F.; Hougaard Bennekou, Susanne; Klein, Michael; et. al.
Zeitschriftenaufsatz
2018Scientific opinion on pesticides in foods for infants and young children
Ockleford, Colin; Adriaanse, Paulien; Hougaard Bennekou, Susanne; Berny, Philippe; Brock, Theodorus; Duquesne, Sabine; Grilli, Sandro; Hernandez-Jerez, Antonio F.; Klein, Michael; Kuhl, Thomas; Laskowski, Ryszard; Machera, Kyriaki; Pelkonen, Olavi; Pieper, Silvia; Smith, Robert; Stemmer, Michael; Sundh, Ingvar; Teodorovic, Ivana; Tiktak, Aaldrik; Topping, Chris J.; Gundert-Remy, Ursula; Kersting, Mathilde; Waalkens-Berendsen, Ine; Chiusolo, Arianna; Court Marques, Daniele; Dujardin, Bruno; Kass, Georges E; Mohimont, Luc; Nougadere, Alexandre; Reich, Hermine; Wolterink, Gerrit
Zeitschriftenaufsatz
2018Scientific Opinion on the state of the art of Toxicokinetic/Toxicodynamic (TKTD) effect models for regulatory risk assessment of pesticides for aquatic organisms
Ockleford, Colin; Adriaanse, Paulien; Berny, Philippe; Brock, Theodorus; Duquesne, Sabine; Grilli, Sandro; Hernandez-Jerez, Antonio F.; Hougaard Bennekou, Susanne; Klein, Michael; et. al.
Zeitschriftenaufsatz
2018Scientific Opinion on the state of the science on pesticide risk assessment for amphibians and reptiles
Ockleford, Colin; Adriaanse, Paulien; Berny, Philippe; Brock, Theodorus; Duquesne, Sabine; Grilli, Sandro; Hernandez-Jerez, Antonio F.; Hougaard Bennekou, Susanne; Klein, Michael; Kuhl, Thomas; Laskowski, Ryszard; Machera, Kyriaki; Pelkonen, Olavi; Pieper, Silvia; Stemmer, Michael; Sundh, Ingvar; Teodorovic, Ivana; Tiktak, Aaldrik; Topping, Chris J.; Wolterink, Gerrit; Craig, Peter; Jong, Frank de; Manachini, Barbara; Sousa, Paulo; Swarowsky, Klaus; Auteri, Domenica; Arena, Maria; Smith, Rob
Zeitschriftenaufsatz
2018Sicherheit und Wirksamkeitshinweise zum Off-label-Einsatz von Biologikatherapien nach Versagen konventioneller Therapien bei Patienten mit entzündlich rheumatischen Erkrankungen
Proft, F.; Schulze-Koops, H.; Grunke, M.; Schrezenmeier, E.; Halleck, F.; Henes, J.; Unger, L.; Schmidt, E.; Fiehn, C.; Jacobi, A.; Iking-Konert, C.; Kneitz, C.; Schmidt, R.E.; Bannert, B.; Voll, R.E.; Fischer-Betz, R.; Kötter, I.; Tony, H.P.; Holle, J.; Aringer, M.; Erler, A.; Behrens, F.; Burmester, G.R.; Dörner, T.
Zeitschriftenaufsatz
2018Silver nanoparticles in sewage sludge: Bioavailability of sulfidized silver to the terrestrial isopod Porcellio scaber
Kampe, Sebastian; Kägi, Ralf; Schlich, Karsten; Wasmuth, Claus; Hollert, Henner; Schlechtriem, Christian
Zeitschriftenaufsatz
2018Silver nanoparticles in sewage treatment plant effluents: Chronic effects and accumulation of silver in the freshwater amphipod Hyalella azteca
Kühr, Sebastian; Schneider, Stefanie; Meisterjahn, Boris; Schlich, Karsten; Hund-Rinke, Kerstin; Schlechtriem, Christian
Zeitschriftenaufsatz
2018Simultaneous determination of PUFA-derived pro-resolving metabolites and pathway markers using chiral chromatography and tandem mass spectrometry
Toewe, A.; Balas, L.; Durand, T.; Geisslinger, G.; Ferreirós, N.
Zeitschriftenaufsatz
2018Simultaneous response in several domains in patients with psoriatic disease treated with etanercept as monotherapy or in combination with conventional synthetic disease-modifying antirheumatic drugs
Behrens, F.; Meier, L.; Prinz, J.C.; Jobst, J.; Lippe, R.; Löschmann, P.-A.; Lorenz, H.-M.
Zeitschriftenaufsatz
2018Single-cell cloning enables the selection of more productive Drosophila melanogaster S2 cells for recombinant protein expression
Zitzmann, J.; Schreiber, C.; Eichmann, J.; Bilz, R.O.; Salzig, D.; Weidner, T.; Czermak, P.
Zeitschriftenaufsatz
2018The siRNA-mediated knockdown of GluN3A in 46C-derived neural stem cells affects mRNA expression levels of neural genes, including known iGluR interactors
Pachernegg, Svenja; Eilebrecht, Sebastian; Eilebrecht, Elke; Schöneborn, Hendrik; Neumann, Sebastian; Benecke, Arndt G.; Hollmann, Michael
Zeitschriftenaufsatz
2018Small rubber particle proteins from Taraxacum brevicorniculatum promote stress tolerance and influence the size and distribution of lipid droplets and artificial poly(cis-1,4-isoprene) bodies
Laibach, N.; Schmidl, S.; Müller, B.; Bergmann, M.; Prüfer, D.; Schulze Gronover, C.
Zeitschriftenaufsatz
2018The sneaking ligand approach for cell type-specific modulation of intracellular signalling pathways
Sehnert, B.; Burkhardt, H.; Finzel, S.; Dübel, S.; Voll, R.E.
Zeitschriftenaufsatz
2018Sphingosine kinase 2 modulates retinal neovascularization in the mouse model of oxygen-induced retinopathy
Eresch, J.; Stumpf, M.; Koch, A.; Vutukuri, R.; Ferreiros, N.; Schreiber, Y.; Schröder, K.; Devraj, K.; Popp, R.; Huwiler, A.; Hattenbach, L.-O.; Pfeilschifter, J.; Pfeilschifter, W.
Zeitschriftenaufsatz
2018Statistische Auswertung von Messungen zur Kontamination von Biota/Fischen mit Schadstoffen im Einzugsgebiet des Rheins in den Jahren 2014/2015
Fliedner, Annette; Müller, Martin
Bericht
2018Stellenwert der Kombination von Biologika mit Methotrexat in der Behandlung der Psoriasisarthritis - Fragen bleiben offen
Dauth, S.; Köhm, M.; Rossmanith, T.; Herrmann, E.; Lehn, A.; Burkhardt, H.; Behrens, F.
Zeitschriftenaufsatz
2018Structure-activity analysis of CJ-15,801 analogues that interact with Plasmodium falciparum pantothenate kinase and inhibit parasite proliferation
Spry, C.; Sewell, A.L.; Hering, Y.; Villa, M.V.J.; Weber, J.; Hobson, S.J.; Harnor, S.J.; Gul, S.; Marquez, R.; Salib, K.J.
Zeitschriftenaufsatz
2018Synaptic phospholipids as a new target for cortical hyperexcitability and E/I balance in psychiatric disorders
Thalman, C.; Horta, G.; Qiao, L.; Endle, H.; Tegeder, I.; Cheng, H.; Laube, G.; Sigurdsson, T.; Hauser, M.J.; Tenzer, S.; Distler, U.; Aoki, J.; Morris, A.J.; Geisslinger, G.; Röper, J.; Kirischuk, S.; Luhmann, H.J.; Radyushkin, K.; Nitsch, R.; Vogt, J.
Zeitschriftenaufsatz
2018T Cell Phenotype and T Cell Receptor Repertoire in Patients with Major Depressive Disorder
Patas, K.; Willing, A.; Demiralay, C.; Engler, J.B.; Lupu, A.; Ramien, C.; Schäfer, T.; Gach, C.; Stumm, L.; Chan, K.; Vignali, M.; Arck, P.C.; Friese, M.A.; Pless, O.; Wiedemann, K.; Agorastos, A.; Gold, S.M.
Zeitschriftenaufsatz
2018Therapeutics discovery: From bench to first in-human trials
Al-Hujaily, E.M.; Khatlani, T.; Alehaideb, Z.; Ali, R.; Almuzaini, B.; Alrfaei, B.M.; Iqbal, J.; Islam, I.; Malik, S.; Marwani, B.A.; Massadeh, S.; Muzaini, B.; Nehdi, A.; Alsomaie, B.; Debasi, B.; Bushnak, I.; Noibi, S.; Hussain, S.; Wajid, W.A.; Armand, J.-P.; Gul, S.; Oyarzabal, J.; Rais, R.; Bountra, C.; Alaskar, A.; Al Knawy, B.; Boudjelal, M.
Zeitschriftenaufsatz
2018Total Synthesis and Structural Revision of the Antibiotic Tetrapeptide GE81112A
Jürjens, G.; Schuler, S.M.M.; Kurz, M.; Petit, S.; Couturier, C.; Jeannot, F.; Nguyen, F.; Wende, R.C.; Hammann, P.E.; Wilson, D.N.; Bacqué, E.; Pöverlein, C.; Bauer, A.
Zeitschriftenaufsatz
2018Two-pronged approach to anti-inflammatory therapy through the modulation of the arachidonic acid cascade
Sala, A.; Proschak, E.; Steinhilber, D.; Rovati, G.E.
Zeitschriftenaufsatz
2018UDP-glucose ceramide glucosyltransferase activates AKT, promoted proliferation, and doxorubicin resistance in breast cancer cells
Wegner, M.-S.; Schömel, N.; Gruber, L.; Örtel, S.B.; Kjellberg, M.A.; Mattjus, P.; Kurz, J.; Trautmann, S.; Peng, B.; Wegner, M.; Kaulich, M.; Ahrends, R.; Geisslinger, G.; Grösch, S.
Zeitschriftenaufsatz
2018The UDP-glucose ceramide glycosyltransferase (UGCG) and the link to multidrug resistance protein 1 (MDR1)
Wegner, M.-S.; Gruber, L.; Mattjus, P.; Geisslinger, G.; Grösch, S.
Zeitschriftenaufsatz
2018A unique fungal strain collection from Vietnam characterized for high performance degraders of bioecological important biopolymers and lipids
Brandt, S.C.; Ellinger, B.; Nguyen, T. van; Thi, Q.D.; Nguyen, G. van; Baschien, C.; Yurkov, A.; Hahnke, R.L.; Schäfer, W.; Gand, M.
Zeitschriftenaufsatz
2018Upregulating the mevalonate pathway and repressing sterol synthesis in Saccharomyces cerevisiae enhances the production of triterpenes
Bröker, J.N.; Müller, B.; Deenen, N. van; Prüfer, D.; Schulze Gronover, C.
Zeitschriftenaufsatz
2018Uptake and effects of cerium(III) and cerium oxide nanoparticles to Chlamydomonas reinhardtii
Kosak, Lena A.; Brandt, Tanja; Sigg, Laura; Behra, Renata
Zeitschriftenaufsatz
2018Urate transporter inhibitor lesinurad is a selective peroxisome proliferator-activated receptor gamma modulator (sPPARγM) in vitro
Heitel, P.; Gellrich, L.; Heering, J.; Goebel, T.; Kahnt, A.; Proschak, E.; Schubert-Zsilavecz, M.; Merk, D.
Zeitschriftenaufsatz
2018Use of Computational Functional Genomics in Drug Discovery and Repurposing for Analgesic Indications
Lötsch, J.; Kringel, D.
Zeitschriftenaufsatz