Fraunhofer-Gesellschaft

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Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2019Bioconcentration studies with the freshwater amphipod Hyalella azteca: Are the results predictive of bioconcentration in fish?
Schlechtriem, Christian; Kampe, Sebastian; Bruckert, Hans-Jörg; Bischof, Ina; Ebersbach, Ina; Kosfeld, Verena; Kotthoff, Matthias; Schäfers, Christoph; L’Haridon, Jacques
Zeitschriftenaufsatz
2019Biodegradation of Volatile Chemicals in Soil: Separating Volatilization and Degradation in an Improved Test Setup (OECD 307)
Shrestha, Prasit; Meisterjahn, Boris; Klein, Michael; Mayer, Philipp; Birch, Heidi; Hughes, Christopher B.; Hennecke, Dieter
Zeitschriftenaufsatz
2019A comparison of log Kow (n‑octanol-water partition coefficient) values for non‑ionic, anionic, cationic and amphoteric surfactants determined using predictions and experimental methods
Hodges, Geoff; Eadsforth, Charles; Bossuyt, Bart; Bouvy, Alain; Enrici, Marie‑Helene; Geurts, Marc; Kotthoff, Matthias; Michie, Eleanor; Miller, Dennis; Müller, Josef; Oetter, Gunter; Roberts, Jayne; Schowanek, Diederik; Sun, Ping; Venzmer, Joachim
Zeitschriftenaufsatz
2019Comparison of the environmental properties of parasiticides and harmonisation of the basis for environmental assessment at the EU level
Römbke, Jörg; Duis, Karen; Egeler, Philipp; Gilberg, Daniel; Schuh, Christine; Herrchen, Monika; Hennecke, Dieter; Hölzle, Ludwig E.; Heilmann-Thudium, Brigitte; Wohde, Manuel; Wagner, Julia; Düring, Rolf-Alexander
Bericht
2019Driving next-generation autophagy researchers towards translation (DRIVE), an international PhD training program on autophagy
Kraft, C.; Boya, P.; Codogno, P.; Elazar, Z.; Eskelinen, E.-L.; Farres, J.; Kirkin, V.; Jungbluth, H.; Martinez, A.; Pless, O.; Primard, C.; Proikas-Cezanne, T.; Simonsen, A.; Reggiori, F.
Zeitschriftenaufsatz
2019Evolutionary ecology of parasitic fungi and their host insects
Vilcinskas, A.
Zeitschriftenaufsatz
2019First evidence of anticoagulant rodenticides in fish and suspended particulate matter: Spatial and temporal distribution in German freshwater aquatic systems
Kotthoff, Matthias; Rüdel, Heinz; Jürling, Heinrich; Severin, Kevin; Hennecke, Stephan; Friesen, Anton; Koschorreck, Jan
Zeitschriftenaufsatz
2019Fraunhofer-Institut für Molekularbiologie und Angewandte Oekologie. Jahresbericht 2018
 
Jahresbericht
2019Generation of transgenic cell suspension cultures of the model legume Medicago truncatula: A rapid method for Agrobacterium mediated gene transfer
Santos, Rita B.; Pires, Ana Sofia; Hoorn, Renier A.L. van der; Schiermeyer, Andreas; Abranches, Rita
Zeitschriftenaufsatz
2019The immunome of soy bean allergy: Comprehensive identification and characterization of epitopes
Kern, Karolin; Havenith, Heide; Delaroque, Nicolas; Rautenberger, Paul; Lehmann, Jörg; Fischer, Markus; Spiegel, Holger; Schillberg, Stefan; Ehrentreich-Förster, Eva; Aurich, Stefanie; Treudler, Regina; Szardenings, Michael
Zeitschriftenaufsatz
2019Levels, accumulation patterns and retrospective trends of perfluoroalkyl acids (PFAAs) in terrestrial ecosystems over the last three decades
Falk, Sandy; Stahl, Thorsten; Fliedner, Annette; Rüdel, Heinz; Tarricone, Kathrin; Brunn, Hubertus; Koschorreck, Jan
Zeitschriftenaufsatz
2019Passive equilibrium sampling of hydrophobic organic compounds in homogenised fish tissues of low lipid content
Rojo-Nieto, Elisa; Muz, Melis; Koschorreck, Jan; Rüdel, Heinz; Jahnke, Annika
Zeitschriftenaufsatz
2019Practical advice for selecting or determining trophic magnification factors for application under the European Union water framework directive
Kidd, K.A.; Burkhard, Lawrence P.; Babut, M.; Borgå, Katrine; Muir, Derek C.G.; Perceval, Olivier; Ruedel, Heinz; Woodburn, Kent; Embry, Michelle R.
Zeitschriftenaufsatz
2019Rating the risks of anticoagulant rodenticides in the aquatic environment: A review
Regnery, Julia; Friesen, Anton; Geduhn, Anke; Göckener, Bernd; Kotthoff, Matthias; Parrhysius, Pia; Petersohn, Eleonora; Reifferscheid, Georg; Schmolz, Erik; Schulz, Robert S.; Schwarzbauer, Jan; Brinke, Marvin
Zeitschriftenaufsatz
2019Testing effects of pesticides on macroinvertebrate communities in outdoor stream mesocosms using carbaryl as example test item
Beuter, Liesa‑Kristin; Dören, László; Hommen, Udo; Kotthoff, Matthias; Schäfers, Christoph; Ebke, Klaus-Peter
Zeitschriftenaufsatz
201820-HETE promotes glucose-stimulated insulin secretion in an autocrine manner through FFAR1
Tunaru, S.; Bonnavion, R.; Brandenburger, I.; Preussner, J.; Thomas, D.; Scholich, K.; Offermanns, S.
Zeitschriftenaufsatz
20188-Methoxypsoralen Plus Ultraviolet A Reduces the Psoriatic Response to Imiquimod in a Murine Model
Shirsath, N.; Wagner, K.; Tangermann, S.; Schlederer, M.; Ringel, C.; Kenner, L.; Brüne, B.; Wolf, P.
Zeitschriftenaufsatz
2018Abatacept used in combination with non-methotrexate disease-modifying antirheumatic drugs
Alten, R.; Burkhardt, H.; Feist, E.; Krüger, K.; Rech, J.; Rubbert-Roth, A.; Voll, R.E.; Elbez, Y.; Rauch, C.
Zeitschriftenaufsatz
2018Achieving adequate protection and suitable food safety indicators
Pucher, J.; Schlechtriem, Christian
Aufsatz in Buch
2018Activation of Adenylyl Cyclase Causes Stimulation of Adenosine Receptors
Pleli, T.; Mondorf, A.; Ferreiros, N.; Thomas, D.; Dvorak, K.; Biondi, R.M.; Heringdorf, D.M.; Zeuzem, S.; Geisslinger, G.; Zimmermann, H.; Waidmann, O.; Piiper, A.
Zeitschriftenaufsatz
2018Advances and Challenges in Drug Design of PPARδ Ligands
Maltarollo, V.G.; Kronenberger, T.; Windshugel, B.; Wrenger, C.; Goulart Trossini, G.H.; Honorio, K.M.
Zeitschriftenaufsatz
2018Advances in the development of procedures to establish the toxicity of non-extractable residues (NER) in soil. LRI-ECO25
Harmsen, Joop; Hennecke, Dieter; Hund-Rinke, Kerstin; Lahr, Joost; Deneer, John
Bericht
2018AICAR inhibits NFκB DNA binding independently of AMPK to attenuate LPS-triggered inflammatory responses in human macrophages
Kirchner, J.; Brüne, B.; Namgaladze, D.
Zeitschriftenaufsatz
2018Analysis and Optimization of Ecotoxicological Models under Uncertainty
Klein, Judith
: Schultz, Rüdiger; Escudero, Laureano F.; Schäfers, Christoph
Dissertation
2018Anti-inflammatory nitro-fatty acids suppress tumor growth by triggering mitochondrial dysfunction and activation of the intrinsic apoptotic pathway in colorectal cancer cells
Kühn, B.; Brat, C.; Fettel, J.; Hellmuth, N.; Maucher, I.V.; Bulut, I.; Hock, K.J.; Grimmer, J.; Manolikakes, G.; Rühl, M.; Kühn, A.; Zacharowski, K.; Matrone, C.; Urbschat, A.; Roos, J.; Steinhilber, D.; Maier, T.J.
Zeitschriftenaufsatz
2018Antiplasmodial activity of tick defensins in a mouse model of malaria
Couto, J.; Tonk, M.; Ferrolho, J.; Antunes, S.; Vilcinskas, A.; Fuente, J. de la; Domingos, A.; Cabezas-Cruz, A.
Zeitschriftenaufsatz
2018Apoptotic Cancer Cells Suppress 5-Lipoxygenase in Tumor-Associated Macrophages
Ringleb, J.; Strack, E.; Angioni, C.; Geisslinger, G.; Steinhilber, D.; Weigert, A.; Brüne, B.
Zeitschriftenaufsatz
2018Artificial neural network-assisted spectrophotometric method for monitoring fructo-oligosaccharides production
Erdős, B.; Grachten, M.; Czermak, P.; Kovács, Z.
Zeitschriftenaufsatz
2018Aryl thiosemicarbazones for the treatment of trypanosomatidic infections
Linciano, P.; Moraes, C.B.; Alcantara, L.M.; Franco, C.H.; Pascoalino, B.; Freitas-Junior, L.H.; Macedo, S.; Santarem, N.; Cordeiro-da-Silva, A.; Gul, S.; Witt, G.; Kuzikov, M.; Ellinger, B.; Ferrari, S.; Luciani, R.; Quotadamo, A.; Costantino, L.; Costi, M.P.
Zeitschriftenaufsatz
2018Aspergillus-specific antibodies: Targets and applications
Schubert, M.; Spiegel, H.; Schillberg, S.; Nölke, G.
Zeitschriftenaufsatz
2018Assessment of seafood contamination under the marine strategy framework directive: Contributions of the German environmental specimen bank
Fliedner, Annette; Rüdel, Heinz; Knopf, Burkhard; Lohmann, Nina; Paulus, Martin; Jud, Michael; Pirntke, Ulrike; Koschorreck, Jan
Zeitschriftenaufsatz
2018Astrocytic ATX fuels synaptic phospholipid signaling involved in psychiatric disorders
Thalman, C.; Horta, G.; Qiao, L.; Endle, H.; Tegeder, I.; Cheng, H.; Laube, G.; Sigrudsson, T.; Hauser, M.J.; Tenzer, S.; Distler, U.; Aoki, J.; Morris, A.J.; Geisslinger, G.; Röper, J.; Kirischuk, S.; Luhmann, H.J.; Radyushkin, K.; Nitsch, R.; Vogt, J.
Zeitschriftenaufsatz
2018Biomarker und Bildgebung zur Diagnose und Stratifizierung der rheumatoiden Arthritis und Spondylarthritis im BMBF-Verbund ArthroMark
Häupl, T.; Skapenko, A.; Hoppe, B.; Skriner, K.; Burkhardt, H.; Poddubnyy, D.; Ohrndorf, S.; Sewerin, P.; Mansmann, U.; Stuhlmüller, B.; Schulze-Koops, H.; Burmester, G.-R.
Zeitschriftenaufsatz
2018Bioreactor-based production of glycoproteins in plant cell suspension cultures
Holland, T.; Buyel, J.F.
Aufsatz in Buch
2018Biota monitoring under the Water Framework Directive: On tissue choice and fish species selection
Fliedner, Annette; Rüdel, Heinz; Lohmann, Nina; Buchmeier, Georgia; Koschorreck, Jan
Zeitschriftenaufsatz
2018Boosting Anti-Inflammatory Potency of Zafirlukast by Designed Polypharmacology
Schierle, S.; Flauaus, C.; Heitel, P.; Willems, S.; Schmidt, J.; Kaiser, A.; Weizel, L.; Goebel, T.; Kahnt, A.S.; Geisslinger, G.; Steinhilber, D.; Wurglics, M.; Rovati, G.E.; Schmidtko, A.; Proschak, E.; Merk, D.
Zeitschriftenaufsatz
2018Bovine embryo elongation is altered due to maternal fatty acid supplementation
Giller, K.; Drews, B.; Berard, J.; Kienberger, H.; Schmicke, M.; Frank, J.; Spanier, B.; Daniel, H.; Geisslinger, G.; Ulbrich, S.E.
Zeitschriftenaufsatz
2018C5aR activation in the absence of C5a
Syed, S.N.; Rau, E.; Ziegelmann, M.; Sogkas, G.; Brüne, B.; Schmidt, R.E.
Zeitschriftenaufsatz
2018Cationic polyacrylamide copolymers (PAMs): Environmental half life determination in sludge‑treated soil
Hennecke, Dieter; Bauer, Angela; Herrchen, Monika; Wischerhoff, Erik; Gores, Friedhelm
Zeitschriftenaufsatz
2018Cell adhesion-induced transient interaction of ADAM15 with poly(A) binding protein at the cell membrane colocalizes with mRNA translation
Böhm, B.B.; Fehrl, Y.; Janczi, T.; Schneider, N.; Burkhardt, H.
Zeitschriftenaufsatz
2018Cell-free protein synthesis system
Buntru, Matthias; Schillberg, Stefan; Vogel, Simon
Patent
2018Challenges in the Development of a Thiol-Based Broad-Spectrum Inhibitor for Metallo-β-Lactamases
Büttner, D.; Kramer, J.S.; Klingler, F.-M.; Wittmann, S.K.; Hartmann, M.R.; Kurz, C.G.; Kohnhäuser, D.; Weizel, L.; Brüggerhoff, A.; Frank, D.; Steinhilber, D.; Wichelhaus, T.A.; Pogoryelov, D.; Proschak, E.
Zeitschriftenaufsatz
2018Characterization of new anti-IL-6 antibodies revealed high potency candidates for intracellular cytokine detection and specific targeting of IL-6 receptor binding sites
Chouman, Karinna; Korioth-Schmitz, Birgit; Sack, Markus; Engelbert Schmitz, Jörn; Tuan Pham, Anh; Fischer, Rainer; Barth, Stefan; Klockenbring, Torsten; Fendel, Rolf
Zeitschriftenaufsatz
2018Chemosensitivity of human colon cancer cells is influenced by a p53-dependent enhancement of ceramide synthase 5 and induction of autophagy
Brachtendorf, S.; Wanger, R.A.; Birod, K.; Thomas, D.; Trautmann, S.; Wegner, M.-S.; Fuhrmann, D.C.; Brüne, B.; Geisslinger, G.; Grösch, S.
Zeitschriftenaufsatz
2018Combined Proteomic and In Silico Target Identification Reveal a Role for 5-Lipoxygenase in Developmental Signaling Pathways
Brand, S.; Roy, S.; Schröder, P.; Rathmer, B.; Roos, J.; Kapoor, S.; Patil, S.; Pommerenke, C.; Maier, T.; Janning, P.; Eberth, S.; Steinhilber, D.; Schade, D.; Schneider, G.; Kumar, K.; Ziegler, S.; Waldmann, H.
Zeitschriftenaufsatz
2018Comparative analysis of the transcriptome responses of zebrafish embryos after exposure to low concentrations of cadmium, cobalt and copper
Sonnack, Laura; Klawonn, Thorsten; Kriehuber, Ralf; Hollert, Henner; Schäfers, Christoph; Fenske, Martina
Zeitschriftenaufsatz
2018Comparative estrogenicity of endogenous, environmental and dietary estrogens in pregnant women I
Fleck, S.C.; Twaddle, N.C.; Churchwell, M.I.; Doerge, D.R.; Pande, P.; Teeguarden, J.G.
Zeitschriftenaufsatz
2018A comparison of two biorelevant in vitro drug release methods for nanotherapeutics based on advanced physiologically-based pharmacokinetic modelling
Jung, F.; Nothnagel, L.; Gao, F.; Thurn, M.; Vogel, V.; Wacker, M.G.
Zeitschriftenaufsatz
2018Computational functional genomics-based approaches in analgesic drug discovery and repurposing
Lippmann, C.; Kringel, D.; Ultsch, A.; Lötsch, J.
Zeitschriftenaufsatz
2018A coupled fluorescence-based assay for the detection of protein arginine N-methyltransferase 6 (PRMT6) enzymatic activity
Kramer, J.; Désor, V.; Brunst, S.; Wittmann, S.K.; Lausen, J.; Heering, J.; Proschak, A.; Proschak, E.
Zeitschriftenaufsatz
2018Current evidence of cannabinoid-based analgesia obtained in preclinical and human experimental settings
Lötsch, J.; Weyer-Menkhoff, I.; Tegeder, I.
Zeitschriftenaufsatz
2018Current status and perspectives of the molecular farming landscape
Spiegel, H.; Stöger, E.; Twyman, R.M.; Buyel, J.F.
Aufsatz in Buch
2018Decreasing δ13C and δ15N values in four coastal species at different trophic levels indicate a fundamental food-web shift in the southern North and Baltic Seas between 1988 and 2016
Corman, Anna-Marie; Schwemmer, Philipp; Mercker, Moritz; Asmus, Harald; Rüdel, Heinz; Klein, Roland; Boner, Markus; Hofem, Sabine; Koschorreck, Jan; Garthe, Stefan
Zeitschriftenaufsatz
2018Development of a Focused Library of Triazole‐Linked Privileged‐Structure‐Based Conjugates Leading to the Discovery of Novel Phenotypic Hits against Protozoan Parasitic Infections
Uliassi, E.; Piazzi, L.; Belluti, F.; Mazzanti, A.; Kaiser, M.; Brun, R.; Moraes, C.B.; Freitas-Junior, L.H.; Gul, S.; Kuzikov, M.; Ellinger, B.; Borsari, C.; Costi, M.P.; Bolognesi, M.L.
Zeitschriftenaufsatz
2018Development, current applications and future roles of biorelevant two‐stage in vitro testing in drug development
Fiolka, T.; Dressman, J.
Zeitschriftenaufsatz
2018Dielectric Spectroscopy and Optical Density Measurement for the Online Monitoring and Control of Recombinant Protein Production in Stably Transformed Drosophila melanogaster S2 Cells
Zitzmann, J.; Weidner, T.; Eichner, G.; Salzig, D.; Czermak, P.
Zeitschriftenaufsatz
2018Dietary phytol reduces clinical symptoms in experimental autoimmune encephalomyelitis (EAE) at least partially by modulating NOX2 expression
Blum, L.; Tafferner, N.; Spring, I.; Kurz, J.; deBruin, N.; Geisslinger, G.; Parnham, M.J.; Schiffmann, S.
Zeitschriftenaufsatz
2018Differentiation of human iPSCs into VSMCs and generation of VSMC-derived calcifying vascular cells
Trillhaase, A.; Haferkamp, U.; Rangnau, A.; Märtens, M.; Schmidt, B.; Trilck, M.; Seibler, P.; Aherrahrou, R.; Erdmann, J.; Aherrahrou, Z.
Zeitschriftenaufsatz
2018Dimerization quality control via ubiquitylation
Herhaus, L.; Dikic, I.
Zeitschriftenaufsatz
2018Discovery of polar spirocyclic orally bioavailable urea inhibitors of soluble epoxide hydrolase
Lukin, A.; Kramer, J.; Hartmann, M.; Weizel, L.; Hernandez-Olmos, V.; Falahati, K.; Burghardt, I.; Kalinchenkova, N.; Bagnyukova, D.; Zhurilo, N.; Rautio, J.; Forsberg, M.; Ihalainen, J.; Auriola, S.; Leppänen, J.; Konstantinov, I.; Pogoryelov, D.; Proschak, E.; Dar'in, D.; Krasavin, M.
Zeitschriftenaufsatz
2018Downregulation of BTLA on NKT Cells Promotes Tumor Immune Control in a Mouse Model of Mammary Carcinoma
Sekar, D.; Govene, L.; Del Río, M.-L.; Sirait-Fischer, E.; Fink, A.F.; Brüne, B.; Rodriguez-Barbosa, J.I.; Weigert, A.
Zeitschriftenaufsatz
2018Downstream processing of a plant-derived malaria transmission-blocking vaccine candidate
Menzel, S.; Holland, T.; Boes, A.; Spiegel, H.; Fischer, R.; Buyel, J.F.
Zeitschriftenaufsatz
2018Drug-Mediated Intracellular Donation of Nitric Oxide Potently Inhibits 5-Lipoxygenase
Roos, J.; Peters, M.; Maucher, I.V.; Kühn, B.; Fettel, J.; Hellmuth, N.; Brat, C.; Sommer, B.; Urbschat, A.; Piesche, M.; Vogel, A.; Proschak, E.; Blöcher, R.; Buscató, E.; Häfner, A.-K.; Matrone, C.; Werz, O.; Heidler, J.; Wittig, I.; Angioni, C.; Geisslinger, G.; Parnham, M.J.; Zacharowski, K.; Steinhilber, D.; Maier, T.J.
Zeitschriftenaufsatz
2018Efficacy and safety of tregalizumab in patients with rheumatoid arthritis and an inadequate response to methotrexate
Vollenhoven, R.F. van; Keystone, E.C.; Strand, V.; Pacheco-Tena, C.; Vencovský, J.; Behrens, F.; Racewicz, A.; Zipp, D.; Rharbaoui, F.; Wolter, R.; Knierim, L.; Schmeidl, R.; Zhou, X.; Aigner, S.; Dälken, B.; Wartenberg-Demand, A.
Zeitschriftenaufsatz
2018Elimination of different leukaemia subtypes using novel CD89-specific human cytolytic fusion proteins
Gresch, G.; Schenke, L.; Mladenov, R.; Zwirner, S.; Cremer, C.; Niesen, J.; Grieger, E.; Brümmendorf, T.; Jost, E.; Fischer, R.; Stockmeyer, B.; Barth, S.; Nachreiner, T.; Stein, C.
Zeitschriftenaufsatz
2018Elucidation of chemical modifier reactivity towards peptides and proteins and the analysis of specific fragmentation by matrix‐assisted laser desorption/ionization collision‐induced dissociation tandem mass spectrometry
Rühl, M.; Kühn, B.; Roos, J.; Maier, T.J.; Steinhilber, D.; Karas, M.
Zeitschriftenaufsatz
2018Elusive mitochondrial connection to inflammation uncovered
Stolz, A.; Dikic, I.
Zeitschriftenaufsatz
2018Empfehlung zur Einrichtung eines nationalen Observatorien-Netzes für die terrestrische Ökosystemforschung
Kögel-Knabner, Ingrid; Teutsch, Georg; Adrian, Rita; Blanckenburg, Friedhelm von; Flügge, Ulf-Ingo; Kolle, Olaf; Kleinn, Christoph; Küsel, Kirsten; Lischeid, Gunnar; Löw, Alexander; Schäfers, Christoph; Schmid, Hans Peter; Simmer, Clemens; Vereecken, Harry; Walz, Rainer
Bericht
2018Environmental impacts by fragments released from nanoenabled products: A multiassay, multimaterial exploration by the SUN approach
Amorim, Monica J.B.; Lin, Sijie; Schlich, Karsten; Navas, Jose Maria; Brunelli, Andrea; Neubauer, Nicole; Vilsmeier, Klaus; Costa, Anna L.; Gondikas, Andreas; Xia, Tian; Galbis, Liliana; Badetti, Elena; Marcomini, Antonio; Hristozov, Danail; Kammer, Frank von der; Hund-Rinke, Kerstin; Scott-Fordsmand, Janeck J.; Nel, André; Wohlleben, Wendel
Zeitschriftenaufsatz
2018Enzyme membrane reactor system (EMRS) for the bioconversion of lignin-containing substrates by a novel heme peroxidase
Busse, N.
Dissertation
2018Expression and purification of human phosphatase and actin regulator 1 (PHACTR1) in plant-based systems
Gengenbach, B.B.; Müschen, C.R.; Buyel, J.F.
Zeitschriftenaufsatz
2018Fishing for contaminants
Hausen, J.; Otte, J.C.; Legradi, J.; Yang, L.; Strähle, U.; Fenske, M.; Hecker, M.; Tang, S.; Hammers-Wirtz, M.; Hollert, H.; Keiter, S.H.; Ottermanns, R.
Zeitschriftenaufsatz
2018Fitness costs of infection with Serratia symbiotica are associated with greater susceptibility to insecticides in the pea aphid Acyrthosiphon pisum
Skaljac, M.; Kirfel, P.; Grotmann, J.; Vilcinskas, A.
Zeitschriftenaufsatz
2018Four chemical trends will shape the next decade's directions in perfluoroalkyl and polyfluoroalkyl substances research
Kotthoff, Matthias; Bücking, Mark
Zeitschriftenaufsatz
2018Fraunhofer-Institut für Molekularbiologie und Angewandte Oekologie. Jahresbericht 2017/2018
 
Jahresbericht
2018A freshwater mesocosm study into the effects of the neonicotinoid insecticide thiamethoxam at multiple trophic levels
Finnegan, Meaghean C.; Emburey, Simon; Hommen, Udo; Baxter, Leilan R.; Hoekstra, Paul F.; Hanson, Mark L.; Thompson, Helen; Hamer, Mick
Zeitschriftenaufsatz
2018The FT/FD-dependent initiation of flowering under long-day conditions in the day-neutral species Nicotiana tabacum originates from the facultative short-day ancestor Nicotiana tomentosiformis
Beinecke, F.A.; Grundmann, L.; Wiedmann, D.R.; Schmidt, F.J.; Caesar, A.S.; Zimmermann, M.; Lahme, M.; Twyman, R.M.; Prüfer, D.; Noll, G.A.
Zeitschriftenaufsatz
2018Functional exploration of natural networks and ecological communities
Ankenbrand, M.J.; Hohlfeld, S.C.Y.; Weber, L.; Förster, F.; Keller, A.
Zeitschriftenaufsatz
2018Gene silencing in Tribolium castaneum as a tool for the targeted identification of candidate RNAi targets in crop pests
Knorr, E.; Fishilevich, E.; Tenbusch, L.; Frey, M.L.F.; Rangasamy, M.; Billion, A.; Worden, S.E.; Gandra, P.; Arora, K.; Lo, W.; Schulenberg, G.; Valverde-Garcia, P.; Vilcinskas, A.; Narva, K.E.
Zeitschriftenaufsatz
2018The genome sequence of the commercially cultivated mushroom Agrocybe aegerita reveals a conserved repertoire of fruiting-related genes and a versatile suite of biopolymer-degrading enzymes
Gupta, D.K.; Rühl, M.; Mishra, B.; Kleofas, V.; Hofrichter, M.; Herzog, R.; Pecyna, M.J.; Sharma, R.; Kellner, H.; Hennicke, F.; Thines, M.
Zeitschriftenaufsatz
2018Grouping concept for metal and metal oxide nanomaterials with regard to their ecotoxicological effects on algae, daphnids and fish embryos
Hund-Rinke, K.; Schlich, Karsten; Kühnel, Dana; Hellack, Bryan; Kaminski, Heinz; Nickel, Carmen
Zeitschriftenaufsatz
2018Halogenated flame retardants in tree samples applied as bioindicatorsfor atmospheric pollution
Dreyer, Annekatrin; Neugebauer, Frank; Rüdel, Heinz; Klein, Roland; Lohmann, Nina; Rauert, Caren; Koschorreck, Jan
Zeitschriftenaufsatz
2018Heterotypic Ubiquitin Chains: Seeing is Believing
Stolz, A.; Dikic, I.
Zeitschriftenaufsatz
2018High cell density cultivation of Δgor/ΔtrxB E. coli in a chemically defined minimal medium with an enhanced iron concentration
Joachim, M.; Schäfer, J.G.; Gerlach, D.; Czermak, P.
Zeitschriftenaufsatz
2018High titer oncolytic measles virus production process by integration of dielectric spectroscopy as online monitoring system
Grein, T.A.; Loewe, D.; Dieken, H.; Salzig, D.; Weidner, T.; Czermak, P.
Zeitschriftenaufsatz
2018High-sensitive troponin is associated with subclinical imaging biosignature of inflammatory cardiovascular involvement in systemic lupus erythematosus
Winau, L.; Baydes, R.H.; Braner, A.; Drott, U.; Burkhardt, H.; Sangle, S.; D'Cruz, D.P.; Carr-White, G.; Marber, M.; Schnoes, K.; Arendt, C.; Klingel, K.; Vogl, T.J.; Zeiher, A.M.; Nagel, E.; Puntmann, V.O.
Zeitschriftenaufsatz
2018Highly efficient genome editing by homology-directed repair using Cas9 protein in Ceratitis capitata
Aumann, R.A.; Schetelig, M.F.; Häcker, I.
Zeitschriftenaufsatz
2018How to effectively treat acute leukemia patients bearing MLL-rearrangements?
Steinhilber, D.; Marschalek, R.
Zeitschriftenaufsatz
2018How to measure release from nanosized carriers?
Nothnagel, L.; Wacker, M.G.
Zeitschriftenaufsatz
2018Human pharmacological approaches to TRP-ion-channel-based analgesic drug development
Weyer-Menkhoff, I.; Lötsch, J.
Zeitschriftenaufsatz
2018Identification and characterization of natural viruses associated with the invasive insect pest Drosophila suzukii
Carrau, T.; Hiebert, N.; Vilcinskas, A.; Lee, K.-Z.
Zeitschriftenaufsatz
2018Identification of approved drugs as potent inhibitors of pregnane X receptor activation with differential receptor interaction profiles
Burk, O.; Kuzikov, M.; Kronenberger, T.; Jeske, J.; Keminer, O.; Thasler, W.E.; Schwab, M.; Wrenger, C.; Windshügel, B.
Zeitschriftenaufsatz
2018Immunological larval polyphenism in the map butterfly Araschnia levana reveals the photoperiodic modulation of immunity
Baudach, A.; Lee, K.-Z.; Vogel, H.; Vilcinskas, A.
Zeitschriftenaufsatz
2018An in silico approach to determine challenges in the bioavailability of ciprofloxacin, a poorly soluble weak base with borderline solubility and permeability characteristics
Hansmann, S.; Miyaji, Y.; Dressman, J.
Zeitschriftenaufsatz
2018In vitro and in silico analysis of the effects of D2 receptor antagonist target binding kinetics on the cellular response to fluctuating dopamine concentrations
Witte, W.E.A. de; Versfelt, J.W.; Kuzikov, M.; Rolland, S.; Georgi, V.; Gribbon, P.; Gul, S.; Huntjens, D.; Graaf, P.H. van der; Danhof, M.; Fernández‐Montalván, A.; Witt, G.; Lange, E.C.M. de
Zeitschriftenaufsatz
2018An in vitro test system for compounds that modulate human inflammatory macrophage polarization
Shiratori, H.; Feinweber, C.; Luckhardt, S.; Wallner, N.; Geisslinger, G.; Weigert, A.; Parnham, M.J.
Zeitschriftenaufsatz
2018Inactivation kinetics of Escherichia Coli and Staphylococcus Aureus by a hydrogen peroxide based disinfectant
Grigoryan, K.; Badalyan, G.; Nersisyan, L.; Tavadyan, L.; Sargsyan, M.
Zeitschriftenaufsatz
2018Inhibition of 53BP1 favors homology-dependent DNA repair and increases CRISPR-Cas9 genome-editing efficiency
Canny, M.D.; Moatti, N.; Wan, L.C.K.; Fradet-Turcotte, A.; Krasner, D.; Mateos-Gomez, P.A.; Zimmermann, M.; Orthwein, A.; Juang, Y.-C.; Zhang, W.; Noordermeer, S.M.; Seclen, E.; Wilson, M.D.; Vorobyov, A.; Munro, M.; Ernst, A.; Ng, T.F.; Cho, T.; Cannon, P.M.; Sidhu, S.S.; Sicheri, F.; Durocher, D.
Zeitschriftenaufsatz
2018Insights into catalysis and function of phosphoribosyl-linked serine ubiquitination
Kalayil, S.; Bhogaraju, S.; Bonn, F.; Shin, D.; Liu, Y.; Gan, N.; Basquin, J.; Grumati, P.; Luo, Z.-Q.; Dikic, I.
Zeitschriftenaufsatz
2018Ixekizumab is efficacious when used alone or when added to conventional synthetic disease-modifying antirheumatic drugs (cDMARDs) in patients with active psoriatic arthritis and previous inadequate response or intolerance to tumour necrosis factor inhibitors
Nash, P.; Behrens, F.; Orbai, A.-M.; Rathmann, S.S.; Adams, D.H.; Benichou, O.; Deodhar, A.
Zeitschriftenaufsatz
2018Knotting nets. Molecular junctions of interconnecting endocrine axes identified by application of the adverse outcome pathway (AOP) concept
Brüggemann, Maria; Licht, Oliver; Fetter, Éva; Teigeler, Matthias; Schäfers, Christoph; Eilebrecht, Elke
Zeitschriftenaufsatz
2018The levels of peroxisomal catalase protein and activity modulate the onset of cell death in tobacco BY-2 cells via reactive oxygen species levels and autophagy
Tyutereva, Elena V.; Dobryakova, Ksenia S.; Schiermeyer, Andreas; Shishova, Maria F.; Pawlowski, Katharina; Demidchik, Vadim; Reumann, Sigrun; Voitsekhovskaja, Olga V.
Zeitschriftenaufsatz
2018A linear epitope coupled to DsRed provides an affinity ligand for the capture of monoclonal antibodies
Rühl, C.; Knödler, M.; Opdensteinen, P.; Buyel, J.F.
Zeitschriftenaufsatz
2018Long-term effects of three different silver sulfide nanomaterials, silver nitrate and bulk silver sulfide on soil microorganisms and plants
Schlich, Karsten; Hoppe, Martin; Kraas, Marco; Schubert, Jonas; Chanana, Munish; Hund-Rinke, Kerstin
Zeitschriftenaufsatz
2018Low protease content in Medicago truncatula cell cultures facilitates recombinant protein production
Santos, Rita B.; Chandrasekar, Balakumaran; Mandal, Manoj K.; Kaschani, Farnush; Kaiser, Markus; Both, Leonard; Hoorn, Renier A.L. van der; Schiermeyer, Andreas; Abranches, Rita
Zeitschriftenaufsatz
2018Machine learning in pain research
Lötsch, J.; Ultsch, A.
Zeitschriftenaufsatz
2018A machine-learned analysis of human gene polymorphisms modulating persisting pain points to major roles of neuroimmune processes
Kringel, D.; Lippmann, C.; Parnham, M.J.; Kalso, E.; Ultsch, A.; Lötsch, J.
Zeitschriftenaufsatz
2018Machine-learned analysis of quantitative sensory testing responses to noxious cold stimulation in healthy subjects
Weyer-Menkhoff, I.; Thrun, M.C.; Lötsch, J.
Zeitschriftenaufsatz
2018Machine-learned selection of psychological questionnaire items relevant to the development of persistent pain after breast cancer surgery
Lötsch, J.; Sipilä, R.; Dimova, V.; Kalso, E.
Zeitschriftenaufsatz
2018Machine-learning based lipid mediator serum concentration patterns allow identification of multiple sclerosis patients with high accuracy
Lötsch, J.; Schiffmann, S.; Schmitz, K.; Brunkhorst, R.; Lerch, F.; Ferreiros, N.; Wicker, S.; Tegeder, I.; Geisslinger, G.; Ultsch, A.
Zeitschriftenaufsatz
2018Machine-learning-derived classifier predicts absence of persistent pain after breast cancer surgery with high accuracy
Lötsch, J.; Sipilä, R.; Tasmuth, T.; Kringel, D.; Estlander, A.-M.; Meretoja, T.; Kalso, E.; Ultsch, A.
Zeitschriftenaufsatz
2018Mannan-induced Nos2 in macrophages enhances IL-17–driven psoriatic arthritis by innate lymphocytes
Zhong, J.; Scholz, T.; Yau, A.C.Y.; Guerard, S.; Hüffmeier, U.; Burkhardt, H.; Holmdahl, R.
Zeitschriftenaufsatz
2018Manufacturing and Safety Guidelines for Manufactured Functionalized Nanomaterials in Pharmaceutics
Wacker, M.G.; Janas, C.; Ferreira, F.S.; Vieira, F.P.
Aufsatz in Buch
2018Mechanism and medical implications of mammalian autophagy
Dikic, I.; Elazar, Z.
Zeitschriftenaufsatz
2018Metabolomic Profiles for Primary Progressive Multiple Sclerosis Stratification and Disease Course Monitoring
Stoessel, D.; Stellmann, J.-P.; Willing, A.; Behrens, B.; Rosenkranz, S.C.; Hodecker, S.C.; Stürner, K.H.; Reinhardt, S.; Fleischer, S.; Deuschle, C.; Maetzler, W.; Berg, D.; Heesen, C.; Walther, D.; Schauer, N.; Friese, M.A.; Pless, O.
Zeitschriftenaufsatz
2018Mitochondrial fragmentation in human macrophages attenuates palmitate-induced inflammatory responses
Zezina, E.; Snodgrass, R.G.; Schreiber, Y.; Zukunft, S.; Schürmann, C.; Meyer zu Heringdorff, D.; Geisslinger, G.; Fleming, I.; Brandes, R.P.; Brüne, B.; Namgaladze, D.
Zeitschriftenaufsatz
2018Molecular techniques for the detection and identification of yeasts in wine
Diaz, Cecilia; Badalyan, Grigori; Bücking, Mark
Aufsatz in Buch
2018Mutations in PMPCB Encoding the Catalytic Subunit of the Mitochondrial Presequence Protease Cause Neurodegeneration in Early Childhood
Vögtle, F.-N.; Brändl, B.; Larson, A.; Pendziwiat, M.; Friederich, M.W.; White, S.M.; Basinger, A.; Kücükköse, C.; Muhle, H.; Jähn, J.A.; Keminer, O.; Helbig, K.L.; Delto, C.F.; Myketin, L.; Mossmann, D.; Burger, N.; Miyake, N.; Burnett, A.; Baalen, A. van; Lovell, M.A.; Matsumoto, N.; Walsh, M.; Yu, H.-C.; Shinde, D.N.; Stephani, U.; Hove, J.L.K. van; Müller, F.-J.; Helbig, I.
Zeitschriftenaufsatz
2018Mutual inversion of flurbiprofen enantiomers in various rat and mouse strains
Bruin, N. de; Ferreirós, N.; Schmidt, M.; Hofmann, M.; Angioni, C.; Geisslinger, G.; Parnham, M.J.
Zeitschriftenaufsatz
2018Nanomaterials: Certain aspects of application, risk assessment and risk communication
Laux, Peter; Tentschert, Jutta; Riebeling, Christian; Braeuning, Albert; Creutzenberg, Otto; Epp, Astrid; Fessard, Valérie; Haas, Karl-Heinz; Haase, Andrea; Hund-Rinke, Kerstin; Jakubowski, Norbert; Kearns, Peter; Lampen, Alfonso; Rauscher, Hubert; Schoonjans, Reinhilde; Störmer, Angela; Thielmann, Axel; Mühle, Uwe; Luch, Andreas
Zeitschriftenaufsatz
2018Nanopharmaceuticals for wound healing
Ashtikar, M.; Wacker, M.G.
Zeitschriftenaufsatz
2018Non-invasive bioluminescence imaging as a standardized assessment measure in mouse models of dermal inflammation
Hofmann, M.C.J.; Schmidt, M.; Arne, O.; Geisslinger, G.; Parnham, M.J.; Bruin, N.M.W.J. de
Zeitschriftenaufsatz
2018Novel sensor platform for rapid detection and quantification of coliforms on food contact surfaces
Badalyan, Grigori; Diaz, Cecilia; Bücking, Mark; Lipski, André
Zeitschriftenaufsatz
2018Nutritional immunology: Diversification and diet-dependent expression of antimicrobial peptides in the black soldier fly Hermetia illucens
Vogel, H.; Müller, A.; Heckel, D.G.; Gutzeit, H.; Vilcinskas, A.
Zeitschriftenaufsatz
2018On the relationship of anthranilic derivatives structure and the FXR (Farnesoid X receptor) agonist activity
Kronenberger, T.; Windshügel, B.; Wrenger, C.; Honorio, K.M.; Maltarollo, V.G.
Zeitschriftenaufsatz
2018Optimizing the composition of a synthetic cellulosome complex for the hydrolysis of softwood pulp
Leis, B.; Held, C.; Andreeßen, B.; Liebl, W.; Graubner, S.; Schulte, L.-P.; Schwarz, W.H.; Zverlov, V.V.
Zeitschriftenaufsatz
2018Oral plasma kallikrein inhibitor for prophylaxis in hereditary angioedema
Aygören-Pürsün, E.; Bygum, A.; Grivcheva-Panovska, V.; Magerl, M.; Graff, J.; Steiner, U.C.; Fain, O.; Huissoon, A.; Kinaciyan, T.; Farkas, H.; Lleonart, R.; Longhurst, H.J.; Rae, W.; Triggiani, M.; Aberer, W.; Cancian, M.; Zanichelli, A.; Smith, W.B.; Baeza, M.L.; Du-Thanh, A.; Gompels, M.; Gonzalez-Quevedo, T.; Greve, J.; Guilarte, M.; Katelaris, C.; Dobo, S.; Cornpropst, M.; Clemons, D.; Fang, L.; Collis, P.; Sheridan, W.; Maurer, M.; Cicardi, M.
Zeitschriftenaufsatz
2018The oxidized linoleic acid metabolite 12,13-DiHOME mediates thermal hyperalgesia during inflammatory pain
Zimmer, B.; Angioni, C.; Osthues, T.; Toewe, A.; Thomas, D.; Pierre, S.C.; Geisslinger, G.; Scholich, K.; Sisignano, M.
Zeitschriftenaufsatz
2018Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells
Hitzel, J.; Lee, E.; Zhang, Y.; Bibli, S.I.; Li, X.; Zukunft, S.; Pflüger, B.; Hu, J.; Schürmann, C.; Vasconez, A.E.; Oo, J.A.; Kratzer, A.; Kumar, S.; Rezende, F.; Josipovic, I.; Thomas, D.; Giral, H.; Schreiber, Y.; Geisslinger, G.; Fork, C.; Yang, X.; Sigala, F.; Romanoski, C.E.; Kroll, J.; Jo, H.; Landmesser, U.; Lusis, A.J.; Namgaladze, D.; Fleming, I.; Leisegang, M.S.; Zhu, J.; Brandes, R.P.
Zeitschriftenaufsatz
2018Physical behavior and sampling of airborne particles
Hochrainer, D.
Aufsatz in Buch
2018Plants as sources of natural and recombinant anti-cancer agents
Buyel, J.F.
Zeitschriftenaufsatz
2018Population-specific expression of antimicrobial peptides conferring pathogen resistance in the invasive ladybird Harmonia axyridis
Gegner, T.; Schmidtberg, H.; Vogel, H.; Vilcinskas, A.
Zeitschriftenaufsatz
2018The portal vein as a distinct immunological compartment
Queck, A.; Rueschenbaum, S.; Kubesch, A.; Cai, C.; Zeuzem, S.; Weigert, A.; Brüne, B.; Nour-Eldin, A.; Gruber-Rouh, T.; Vogl, T.; Lange, C.M.
Zeitschriftenaufsatz
2018Primary fish hepatocytes as in vitro test system to study the metabolism of xenobiotics in fish
Bischof, Ina
: Segner, Helmut; Schlechtriem, Christian
Dissertation
2018Promoter construct for cell-free protein synthesis
Buntru, Matthias; Schillberg, Stefan; Vogel, Simon
Patent
2018The prostaglandin E2 receptor EP3 controls CC-chemokine ligand 2–mediated neuropathic pain induced by mechanical nerve damage
Treutlein, E.-M.; Kern, K.; Weigert, A.; Tarighi, N.; Schuh, C.-D.; Nüsing, R.M.; Schreiber, Y.; Ferreirós, N.; Brüne, B.; Geisslinger, G.; Pierre, S.; Scholich, K.
Zeitschriftenaufsatz
2018Proteomic analysis of CHO cell lines producing high and low quantities of a recombinant antibody before and after selection with methotrexate
Hausmann, R.; Chudobová, I.; Spiegel, H.; Schillberg, S.
Zeitschriftenaufsatz
2018Redox-signals and macrophage biology
Weigert, A.; Knethen, A. von; Fuhrmann, D.; Dehne, N.; Brüne, B.
Zeitschriftenaufsatz
2018A reference genome of the Chinese hamster based on a hybrid assembly strategy
Rupp, O.; MacDonald, M.L.; Li, S.; Dhiman, H.; Polson, S.; Griep, S.; Heffner, K.; Hernandez, I.; Brinkrolf, K.; Jadhav, V.; Samoudi, M.; Hao, H.; Kingham, B.; Goesmann, A.; Betenbaugh, M.J.; Lewis, N.E.; Borth, N.; Lee, K.H.
Zeitschriftenaufsatz
2018The relevance of ceramides and their synthesizing enzymes for multiple sclerosis
Kurz, J.; Brunkhorst, R.; Foerch, C.; Blum, L.; Henke, M.; Gabriel, L.; Ulshöfer, T.; Ferreiros, N.; Parnham, M.J.; Geisslinger, G.; Schiffmann, S.
Zeitschriftenaufsatz
2018Reliable high-density energy storage in Si-doped HfO2 thin films on 3D-structures
Kühnel, Kati; Riedel, Stefan; Mart, Clemens; Weinreich, Wenke
Vortrag
2018Response of the Mayfly (Cloeon Dipterum) to chronic exposure to Thiamethoxam in outdoor Mesocosms
Pickford, Daniel B.; Finnegan, Meaghean C.; Baxter, Leilan R.; Böhmer, Walter; Hanson, Mark L.; Stegger, Petra; Hommen, Udo; Hoekstra, Paul F.; Hamer, Mick
Zeitschriftenaufsatz
2018Revisiting elimination half live as an indicator for bioaccumulation in fish and terrestrial mammals
Goss, Kai-Uwe; Linden, Lukas; Ulrich, Nadin; Schlechtriem, Christian
Zeitschriftenaufsatz
2018S2e-Leitlinie: Therapie der rheumatoiden Arthritis mit krankheitsmodifizierenden Medikamenten
Fiehn, C.; Holle, J.; Iking-Konert, C.; Leipe, J.; Weseloh, C.; Frerix, M.; Alten, R.; Behrens, F.; Baerwald, C.; Braun, J.; Burkhardt, H.; Burmester, G.; Detert, J.; Gaubitz, M.; Gause, A.; Gromnica-Ihle, E.; Kellner, H.; Krause, A.; Kuipers, J.; Lorenz, H.-M.; Müller-Ladner, U.; Nothacker, M.; Nüsslein, H.; Rubbert-Roth, A.; Schneider, M.; Schulze-Koops, H.; Seitz, S.; Sitter, H.; Specker, C.; Tony, H.-P.; Wassenberg, S.; Wollenhaupt, J.; Krüger, K.
Zeitschriftenaufsatz
2018Scientific Opinion about the Guidance of the Chemical Regulation Directorate (UK) on how aged sorption studies for pesticides should be conducted, analysed and used in regulatory assessments
Ockleford, Colin; Hernandez-Jerez, Antonio F.; Hougaard Bennekou, Susanne; Klein, Michael; et. al.
Zeitschriftenaufsatz
2018Scientific opinion on pesticides in foods for infants and young children
Ockleford, Colin; Adriaanse, Paulien; Hougaard Bennekou, Susanne; Berny, Philippe; Brock, Theodorus; Duquesne, Sabine; Grilli, Sandro; Hernandez-Jerez, Antonio F.; Klein, Michael; Kuhl, Thomas; Laskowski, Ryszard; Machera, Kyriaki; Pelkonen, Olavi; Pieper, Silvia; Smith, Robert; Stemmer, Michael; Sundh, Ingvar; Teodorovic, Ivana; Tiktak, Aaldrik; Topping, Chris J.; Gundert-Remy, Ursula; Kersting, Mathilde; Waalkens-Berendsen, Ine; Chiusolo, Arianna; Court Marques, Daniele; Dujardin, Bruno; Kass, Georges E; Mohimont, Luc; Nougadere, Alexandre; Reich, Hermine; Wolterink, Gerrit
Zeitschriftenaufsatz
2018Scientific Opinion on the state of the art of Toxicokinetic/Toxicodynamic (TKTD) effect models for regulatory risk assessment of pesticides for aquatic organisms
Ockleford, Colin; Adriaanse, Paulien; Berny, Philippe; Brock, Theodorus; Duquesne, Sabine; Grilli, Sandro; Hernandez-Jerez, Antonio F.; Hougaard Bennekou, Susanne; Klein, Michael; et. al.
Zeitschriftenaufsatz
2018Scientific Opinion on the state of the science on pesticide risk assessment for amphibians and reptiles
Ockleford, Colin; Adriaanse, Paulien; Berny, Philippe; Brock, Theodorus; Duquesne, Sabine; Grilli, Sandro; Hernandez-Jerez, Antonio F.; Hougaard Bennekou, Susanne; Klein, Michael; Kuhl, Thomas; Laskowski, Ryszard; Machera, Kyriaki; Pelkonen, Olavi; Pieper, Silvia; Stemmer, Michael; Sundh, Ingvar; Teodorovic, Ivana; Tiktak, Aaldrik; Topping, Chris J.; Wolterink, Gerrit; Craig, Peter; Jong, Frank de; Manachini, Barbara; Sousa, Paulo; Swarowsky, Klaus; Auteri, Domenica; Arena, Maria; Smith, Rob
Zeitschriftenaufsatz
2018Sicherheit und Wirksamkeitshinweise zum Off-label-Einsatz von Biologikatherapien nach Versagen konventioneller Therapien bei Patienten mit entzündlich rheumatischen Erkrankungen
Proft, F.; Schulze-Koops, H.; Grunke, M.; Schrezenmeier, E.; Halleck, F.; Henes, J.; Unger, L.; Schmidt, E.; Fiehn, C.; Jacobi, A.; Iking-Konert, C.; Kneitz, C.; Schmidt, R.E.; Bannert, B.; Voll, R.E.; Fischer-Betz, R.; Kötter, I.; Tony, H.P.; Holle, J.; Aringer, M.; Erler, A.; Behrens, F.; Burmester, G.R.; Dörner, T.
Zeitschriftenaufsatz
2018Silver nanoparticles in sewage sludge: Bioavailability of sulfidized silver to the terrestrial isopod Porcellio scaber
Kampe, Sebastian; Kägi, Ralf; Schlich, Karsten; Wasmuth, Claus; Hollert, Henner; Schlechtriem, Christian
Zeitschriftenaufsatz
2018Silver nanoparticles in sewage treatment plant effluents: Chronic effects and accumulation of silver in the freshwater amphipod Hyalella azteca
Kühr, Sebastian; Schneider, Stefanie; Meisterjahn, Boris; Schlich, Karsten; Hund-Rinke, Kerstin; Schlechtriem, Christian
Zeitschriftenaufsatz
2018Simultaneous determination of PUFA-derived pro-resolving metabolites and pathway markers using chiral chromatography and tandem mass spectrometry
Toewe, A.; Balas, L.; Durand, T.; Geisslinger, G.; Ferreirós, N.
Zeitschriftenaufsatz
2018Simultaneous response in several domains in patients with psoriatic disease treated with etanercept as monotherapy or in combination with conventional synthetic disease-modifying antirheumatic drugs
Behrens, F.; Meier, L.; Prinz, J.C.; Jobst, J.; Lippe, R.; Löschmann, P.-A.; Lorenz, H.-M.
Zeitschriftenaufsatz
2018Single-cell cloning enables the selection of more productive Drosophila melanogaster S2 cells for recombinant protein expression
Zitzmann, J.; Schreiber, C.; Eichmann, J.; Bilz, R.O.; Salzig, D.; Weidner, T.; Czermak, P.
Zeitschriftenaufsatz
2018The siRNA-mediated knockdown of GluN3A in 46C-derived neural stem cells affects mRNA expression levels of neural genes, including known iGluR interactors
Pachernegg, Svenja; Eilebrecht, Sebastian; Eilebrecht, Elke; Schöneborn, Hendrik; Neumann, Sebastian; Benecke, Arndt G.; Hollmann, Michael
Zeitschriftenaufsatz
2018Small rubber particle proteins from Taraxacum brevicorniculatum promote stress tolerance and influence the size and distribution of lipid droplets and artificial poly(cis-1,4-isoprene) bodies
Laibach, N.; Schmidl, S.; Müller, B.; Bergmann, M.; Prüfer, D.; Schulze Gronover, C.
Zeitschriftenaufsatz
2018The sneaking ligand approach for cell type-specific modulation of intracellular signalling pathways
Sehnert, B.; Burkhardt, H.; Finzel, S.; Dübel, S.; Voll, R.E.
Zeitschriftenaufsatz
2018Sphingosine kinase 2 modulates retinal neovascularization in the mouse model of oxygen-induced retinopathy
Eresch, J.; Stumpf, M.; Koch, A.; Vutukuri, R.; Ferreiros, N.; Schreiber, Y.; Schröder, K.; Devraj, K.; Popp, R.; Huwiler, A.; Hattenbach, L.-O.; Pfeilschifter, J.; Pfeilschifter, W.
Zeitschriftenaufsatz
2018Statistische Auswertung von Messungen zur Kontamination von Biota/Fischen mit Schadstoffen im Einzugsgebiet des Rheins in den Jahren 2014/2015
Fliedner, Annette; Müller, Martin
Bericht
2018Stellenwert der Kombination von Biologika mit Methotrexat in der Behandlung der Psoriasisarthritis - Fragen bleiben offen
Dauth, S.; Köhm, M.; Rossmanith, T.; Herrmann, E.; Lehn, A.; Burkhardt, H.; Behrens, F.
Zeitschriftenaufsatz
2018Structure-activity analysis of CJ-15,801 analogues that interact with Plasmodium falciparum pantothenate kinase and inhibit parasite proliferation
Spry, C.; Sewell, A.L.; Hering, Y.; Villa, M.V.J.; Weber, J.; Hobson, S.J.; Harnor, S.J.; Gul, S.; Marquez, R.; Salib, K.J.
Zeitschriftenaufsatz
2018Synaptic phospholipids as a new target for cortical hyperexcitability and E/I balance in psychiatric disorders
Thalman, C.; Horta, G.; Qiao, L.; Endle, H.; Tegeder, I.; Cheng, H.; Laube, G.; Sigurdsson, T.; Hauser, M.J.; Tenzer, S.; Distler, U.; Aoki, J.; Morris, A.J.; Geisslinger, G.; Röper, J.; Kirischuk, S.; Luhmann, H.J.; Radyushkin, K.; Nitsch, R.; Vogt, J.
Zeitschriftenaufsatz
2018T Cell Phenotype and T Cell Receptor Repertoire in Patients with Major Depressive Disorder
Patas, K.; Willing, A.; Demiralay, C.; Engler, J.B.; Lupu, A.; Ramien, C.; Schäfer, T.; Gach, C.; Stumm, L.; Chan, K.; Vignali, M.; Arck, P.C.; Friese, M.A.; Pless, O.; Wiedemann, K.; Agorastos, A.; Gold, S.M.
Zeitschriftenaufsatz
2018Therapeutics discovery: From bench to first in-human trials
Al-Hujaily, E.M.; Khatlani, T.; Alehaideb, Z.; Ali, R.; Almuzaini, B.; Alrfaei, B.M.; Iqbal, J.; Islam, I.; Malik, S.; Marwani, B.A.; Massadeh, S.; Muzaini, B.; Nehdi, A.; Alsomaie, B.; Debasi, B.; Bushnak, I.; Noibi, S.; Hussain, S.; Wajid, W.A.; Armand, J.-P.; Gul, S.; Oyarzabal, J.; Rais, R.; Bountra, C.; Alaskar, A.; Al Knawy, B.; Boudjelal, M.
Zeitschriftenaufsatz
2018Total Synthesis and Structural Revision of the Antibiotic Tetrapeptide GE81112A
Jürjens, G.; Schuler, S.M.M.; Kurz, M.; Petit, S.; Couturier, C.; Jeannot, F.; Nguyen, F.; Wende, R.C.; Hammann, P.E.; Wilson, D.N.; Bacqué, E.; Pöverlein, C.; Bauer, A.
Zeitschriftenaufsatz
2018Two-pronged approach to anti-inflammatory therapy through the modulation of the arachidonic acid cascade
Sala, A.; Proschak, E.; Steinhilber, D.; Rovati, G.E.
Zeitschriftenaufsatz
2018UDP-glucose ceramide glucosyltransferase activates AKT, promoted proliferation, and doxorubicin resistance in breast cancer cells
Wegner, M.-S.; Schömel, N.; Gruber, L.; Örtel, S.B.; Kjellberg, M.A.; Mattjus, P.; Kurz, J.; Trautmann, S.; Peng, B.; Wegner, M.; Kaulich, M.; Ahrends, R.; Geisslinger, G.; Grösch, S.
Zeitschriftenaufsatz
2018The UDP-glucose ceramide glycosyltransferase (UGCG) and the link to multidrug resistance protein 1 (MDR1)
Wegner, M.-S.; Gruber, L.; Mattjus, P.; Geisslinger, G.; Grösch, S.
Zeitschriftenaufsatz
2018A unique fungal strain collection from Vietnam characterized for high performance degraders of bioecological important biopolymers and lipids
Brandt, S.C.; Ellinger, B.; Nguyen, T. van; Thi, Q.D.; Nguyen, G. van; Baschien, C.; Yurkov, A.; Hahnke, R.L.; Schäfer, W.; Gand, M.
Zeitschriftenaufsatz
2018Upregulating the mevalonate pathway and repressing sterol synthesis in Saccharomyces cerevisiae enhances the production of triterpenes
Bröker, J.N.; Müller, B.; Deenen, N. van; Prüfer, D.; Schulze Gronover, C.
Zeitschriftenaufsatz
2018Uptake and effects of cerium(III) and cerium oxide nanoparticles to Chlamydomonas reinhardtii
Kosak, Lena A.; Brandt, Tanja; Sigg, Laura; Behra, Renata
Zeitschriftenaufsatz
2018Urate transporter inhibitor lesinurad is a selective peroxisome proliferator-activated receptor gamma modulator (sPPARγM) in vitro
Heitel, P.; Gellrich, L.; Heering, J.; Goebel, T.; Kahnt, A.; Proschak, E.; Schubert-Zsilavecz, M.; Merk, D.
Zeitschriftenaufsatz
2018Use of Computational Functional Genomics in Drug Discovery and Repurposing for Analgesic Indications
Lötsch, J.; Kringel, D.
Zeitschriftenaufsatz