Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2019Activation of group 2 innate lymphoid cells after allergen challenge in asthmatic patients
Winkler, C.; Hochdörfer, T.; Israelsson, E.; Hasselberg, A.; Cavallin, A.; Thörn, K.; Muthas, D.; Shojaee, S.; Lüer, K.; Müller, M.; Mjösberg, J.; Vaarala, O.; Hohlfeld, J.; Pardali, K.
Zeitschriftenaufsatz
2019Adverse effects of long and straight multiwalled carbon nanotubes on cytoskeleton, nuclear lamina, and genome-wide transcriptome of primary human mesothelial cells
Reamon-Buettner, S.M.; Voepel, I.; Hiemisch, A.; Eckert, V.; Schaudien, D.; Ziemann, C.
Abstract
2019Analyses of frequency and sensitivity of affected organs in preclinical studies from RepDose and eTOX database
Afrapoli, F.M.; Escher, S.E.; Bitsch, A.; Simetska, N.
Abstract
2019Analysis of Human Breath by Millimeter-Wave/Terahertz Spectroscopy
Rothbart, N.; Holz, O.; Koczulla, R.; Schmalz, K.; Hübers, H.-W.
Zeitschriftenaufsatz
2019BAL cell gene expression is indicative of outcome and airway basal cell involvement in idiopathic pulmonary fibrosis
Prasse, Antje; Binder, Harald; Schupp, Jonas C.; Kayser, Gian; Bargagli, Elena; Jäger, Benedikt; Hess, Moritz; Rittinghausen, Susanne; Vuga, Louis; Lynn, Heather; Violette, Shelia; Jung, Birgit; Quast, Karsten; Vanaudenaerde, Bart; Xu, Yan; Hohlfeld, Jens M.; Krug, Norbert; Herazo-Maya, Jose D.; Rottoli, Paola; Wuyts, Wim A.; Kaminski, Naftali
Zeitschriftenaufsatz
2019Cabin air quality – Quantitative comparison of volatile air contaminants at different flight phases during 177 commercial flights
Schuchardt, S.; Koch, W.; Rosenberger, W.
Zeitschriftenaufsatz
2019Challenges in working towards an internal threshold of toxicological concern (iTTC) for use in the safety assessment of cosmetics: Discussions from the Cosmetics Europe iTTC Working Group workshop
Ellison, C.A.; Blackburn, K.L.; Carmichael, P.L.; Clewell, H.J.; Cronin, M.T.D.; Desprez, B.; Escher, S.E.; Ferguson, S.S.; Grégoire, S.; Hewitt, N.J.; Hollnagel, H.M.; Klaric, M.; Patel, A.; Salhi, S.; Schepky, A.; Schmitt, B.G.; Wambaugh, J.F.; Worth, A.
Zeitschriftenaufsatz
2019Characterization of Aerosol Release during Spraying of Isocyanate Products
Ehnes, C.; Genz, M.; Duwenhorst, J.; Krasnow, J.; Bleeke, J.; Schwarz, K.; Koch, W.; Schuchardt, S.
Zeitschriftenaufsatz
2019The clinical course of idiopathic pulmonary fibrosis and its association to quality of life over time
Kreuter, M.; Swigris, J.; Pittrow, D.; Geier, S.; Klotsche, J.; Prasse, A.; Wirtz, H.; Koschel, D.; Andreas, S.; Claussen, M.; Grohé, C.; Wilkens, H.; Hagmeyer, L.; Skowasch, D.; Meyer, J.F.; Kirschner, J.; Gläser, S.; Kahn, N.; Welte, T.; Neurohr, C.; Schwaiblmair, M.; Held, M.; Bahmer, T.; Oqueka, T.; Frankenberger, M.; Behr, J.
Zeitschriftenaufsatz
2019Contribution of airway eosinophils in airway wall remodeling in asthma: Role of MMP‐10 and MET
Kuo, C.-H.S.; Pavlidis, S.; Zhu, J.; Loza, M.; Baribaud, F.; Rowe, A.; Pandis, I.; Gibeon, D.; Hoda, U.; Sousa, A.; Wilson, S.J.; Howarth, P.; Shaw, D.; Fowler, S.; Dahlen, B.; Chanez, P.; Krug, N.; Sandstrom, T.; Fleming, L.; Corfield, J.; Auffray, C.; Djukanovic, R.; Sterk, P.J.; Guo, Y.; Adcock, I.M.; Chung, K.F.
Zeitschriftenaufsatz
2019Corrigendum to "The application of new HARD-descriptor available from the CORAL software to building up NOAEL models" [Food Chem. Toxicol. 112 (2018) 544-550]
Toropova, A.P.; Toropov, A.A.; Marzo, M.; Escher, S.E.; Dorne, J.L.; Georgiadis, N.; Benfenati, E.
Zeitschriftenaufsatz
2019Development of a QSAR model for respiratory irritation
Wehr, M.; Karwath, A.; Sarang, S.S.; Rooseboom, M.; Boogaard, P.J.; Escher, S.E.
Abstract
2019Differentiation of Aneugens and Clastogens in the In Vitro Micronucleus Test by Kinetochore Scoring Using Automated Image Analysis
Wilde, S.; Queisser, N.; Holz, C.; Raschke, M.; Sutter, A.
Zeitschriftenaufsatz
2019Effect of Indacaterol/Glycopyrronium on Pulmonary Perfusion and Ventilation in Hyperinflated Patients with Chronic Obstructive Pulmonary Disease (CLAIM)
Vogel-Claussen, J.; Schönfeld, C.-O.; Kaireit, T.F.; Voskrebenzev, A.; Czerner, C.P.; Renne, J.; Tillmann, H.-C.; Berschneider, K.; Hiltl, S.; Bauersachs, J.; Welte, T.; Hohlfeld, J.M.
Zeitschriftenaufsatz
2019Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux
Perotin, J.-M.; Schofield, J.P.R.; Wilson, S.J.; Ward, J.; Brandsma, J.; Strazzeri, F.; Bansal, A.; Yang, X.; Rowe, A.; Corfield, J.; Lutter, R.; Shaw, D.E.; Bakke, P.S.; Caruso, M.; Dahlén, B.; Fowler, S.J.; Horváth, I.; Howarth, P.; Krug, N.; Montuschi, P.; Sanak, M.; Sandström, T.; Sun, K.; Pandis, I.; Auffray, C.; Meulder, B. de; Lefaudeux, D.; Riley, J.H.; Sousa, A.R.; Dahlen, S.-E.; Adcock, I.M.; Chung, K.F.; Sterk, P.J.; Skipp, P.J.; Collins, J.E.; Davies, D.E.; Djukanović, R.
Zeitschriftenaufsatz
2019Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation
Jevnikar, Z.; Östling, J.; Ax, E.; Calven, J.; Thörn, K.; Israelsson, E.; Öberg, L.; Singhania, A.; Lau, L.C.K.; Wilson, S.J.; Ward, J.A.; Chauhan, A.; Sousa, A.R.; Meulder, B. de; Loza, M.J.; Baribaud, F.; Sterk, P.J.; Chung, K.F.; Sun, K.; Guo, Y.; Adcock, I.M.; Payne, D.; Dahlen, B.; Chanez, P.; Shaw, D.E.; Krug, Norbert; Hohlfeld, Jens M.; Sandström, T.; Djukanovic, R.; James, A.; Hinks, T.S.C.; Howarth, P.H.; Vaarala, O.; Geest, M. van; Olsson, H.; Adcock, I.M.; Ahmed, H.; Auffray, C.; Bakke, P.; Bansal, A.T.; Baribaud, F.; Bates, S.; Bel, E.H.; Bigler, J.; Bisgaard, H.; Boedigheimer, M.J.; Bonnelykke, K.; Brandsma, J.; Brinkman, P.; Bucchioni, E.; Burg, D.; Bush, A.; Caruso, M.; Chaiboonchoe, A.; Chanez, P.; Chung, F.K.; Compton, C.H.; Corfield, J.; D'Amico, A.; Dahlen, S.E.; De Meulder, B.; Djukanovic, R.; Erpenbeck, V.J.; Erzen, D.; Fichtner, K.; Fitch, N.; Fleming, L.J.; Formaggio, E.; Fowler, S.J.; Frey, U.; Gahlemann, M.; Geiser, T.; Goss, V.; Guo, Y.; Hashimoto, S.; Haughney, J.; Hedlin,
Zeitschriftenaufsatz
2019Fate of Barium Sulfate Nanoparticles Deposited in the Lungs of Rats
Molina, R.M.; Konduru, N.V.; Queiroz, P.M.; Figueroa, B.; Fu, D.; Ma-Hock, L.; Groeters, S.; Schaudien, D.; Brain, J.D.
Zeitschriftenaufsatz
2019Fraunhofer-Institut für Toxikologie und Experimentelle Medizin. Leistungen und Ergebnisse. Jahresbericht 2018
 
Jahresbericht
2019Identification and quantification of synthetic cannabinoids in 'spice-like' herbal mixtures: Update of the German situation in summer 2018
Ernst, L.; Langer, N.; Bockelmann, A.; Salkhordeh, E.; Beuerle, T.
Zeitschriftenaufsatz
2019Identification of potential emerging chemical risks in food from REACH registered chemicals
Licht, O.; Bitsch, A.; Bohlen, M.L.; Escher, S.E.; Kass, G.; Merten, C.; MacLeod, M.; Noteborn, H.; Schwarz, M.; Oltmanns, J.; Silano, V.
Abstract
2019In Vivo Detection of Circulating Tumor Cells in High-Risk Non-Metastatic Prostate Cancer Patients Undergoing Radiotherapy
Chen, S.; Tauber, G.; Langsenlehner, T.; Schmölzer, L.M.; Pötscher, M.; Riethdorf, S.; Kuske, A.; Leitinger, G.; Kashofer, K.; Czyż, Z.T.; Polzer, B.; Pantel, K.; Sedlmayr, P.; Kroneis, T.; El-Heliebi, A.
Zeitschriftenaufsatz
2019Long-term effects of inhaled nanoparticles in rats - Ceriumdioxide and Bariumsulphate
Ma-Hock, L.; Wiench, K.; Groeters, S.; Ravenzwaay, B. van; Landsiedel, R.; Ernst, H.; Schaudien, D.
Abstract
2019Mapping of regional lung microstructural parameters using hyperpolarized 129Xe dissolved‐phase MRI in healthy volunteers and patients with chronic obstructive pulmonary disease
Kern, A.L.; Gutberlet, M.; Voskrebenzev, A.; Klimes, F.; Rotärmel, A.; Wacker, F.; Hohlfeld, J.M.; Vogel-Claussen, J.
Zeitschriftenaufsatz
2019Microfluidic enrichment, isolation and characterization of disseminated melanoma cells from lymph node samples
Weidele, Kathrin; Stojanović, Nataša; Feliciello, Giancarlo; Markiewicz, Aleksandra; Scheitler, Sebastian; Alberter, Barbara; Renner, Philipp; Haferkamp, Sebastian; Klein, Christoph A.; Polzer, Bernhard
Zeitschriftenaufsatz
2019MicroRNA-144-3p targets relaxin/insulin-like family peptide receptor 1 (RXFP1) expression in lung fibroblasts from patients with idiopathic pulmonary fibrosis
Bahudhanapati, H.; Tan, J.; Dutta, J.A.; Strock, S.B.; Sembrat, J.; Alvarez, D.; Rojas, M.; Jäger, B.; Prasse, A.; Zhang, Y.; Kass, D.J.
Zeitschriftenaufsatz
2019A mouse model for intellectual disability caused by mutations in the X-linked 2'‑O‑methyltransferase Ftsj1 gene
Jensen, L.R.; Garrett, L.; Hölter, S.M.; Rathkolb, B.; Rácz, I.; Adler, T.; Prehn, C.; Hans, W.; Rozman, J.; Becker, L.; Aguilar-Pimentel, J.A.; Puk, O.; Moreth, K.; Dopatka, M.; Walther, D.J.; Bohlen und Halbach, V. von; Rath, M.; Delatycki, M.; Bert, B.; Fink, H.; Blümlein, K.; Ralser, M.; Dijck, A. van; Kooy, F.; Stark, Z.; Müller, S.; Scherthan, H.; Gecz, J.; Wurst, W.; Wolf, E.; Zimmer, A.; Klingenspor, M.; Graw, J.; Klopstock, T.; Busch, D.; Adamski, J.; Fuchs, H.; Gailus-Durner, V.; Hrabě de Angelis, M.; Bohlen und Halbach, O. von; Ropers, H.-H.; Kuss, A.W.
Zeitschriftenaufsatz
2019Novel ETV6‐RUNX1 Mouse Model to Study the Role of ELF‐MF in Childhood B‐Acute Lymphoblastic Leukemia
Campos-Sanchez, E.; Vicente‐Dueñas, C.; Rodríguez‐Hernández, G.; Capstick, M.; Kuster, N.; Dasenbrock, C.; Sánchez-García, I.; Cobaleda, C.
Zeitschriftenaufsatz
2019Occupational Exposure to Antibiotics in Poultry Feeding Farms
Paul, R.; Gerling, S.; Berger, M.; Blümlein, K.; Jäckel, U.; Schuchardt, S.
Zeitschriftenaufsatz
2019Paradigm shift in safety assessment using new approach methods
Graepel, R.; Ter Braak, B.; Escher, S.E.; Fisher, C.; Gardner, I.; Kamp, H.; Kroese, D.; Leist, M.; Moné, M.J.; Pastor, M.; Water, B. van de
Zeitschriftenaufsatz
2019POINT: Should Molecular and Genetic Biomarkers Be Used in the Initial Evaluation of Patients With Fibrotic ILD? Yes
Prasse, A.
Zeitschriftenaufsatz
2019The puzzling issue of silica toxicity: are silanols bridging the gaps between surface states and pathogenicity?
Pavan, C.; Delle Piane, M.; Gullo, M.; Filippi, F.; Fubini, B.; Hoet, P.; Horwell, C.J.; Huaux, F.; Lison, D.; Lo Giudice, C.; Martra, G.; Montfort, E.; Schins, R.; Sulpizi, M.; Wegner, K.; Wyart-Remy, M.; Ziemann, C.; Turci, F.
Zeitschriftenaufsatz
2019Randomized immunotherapy trial in dual‐allergic patients using "active allergen placebo" as control
Wagenmann, M.; Worm, M.; Akboga, Y.; Karjalainen, M.; Hohlfeld, J.M.
Zeitschriftenaufsatz
2019The rat bone marrow micronucleus test: Statistical considerations on historical negative control data
Igl, B.-W.; Bitsch, A.; Bringezu, F.; Chang, S.; Dammann, M.; Frötschl, R.; Harm, V.; Kellner, R.; Krzykalla, V.; Lott, J.; Nern, M.; Pfuhler, S.; Queisser, N.; Schulz, M.; Sutter, A.; Vaas, L.; Vonk, R.; Zellner, D.; Ziemann, C.
Zeitschriftenaufsatz
2019Regional investigation of lung function and microstructure parameters by localized 129Xe chemical shift saturation recovery and dissolved‐phase imaging
Kern, A.L.; Gutberlet, M.; Qing, K.; Voskrebenzev, A.; Klimes, F.; Kaireit, T.F.; Czerner, C.; Biller, H.; Wacker, F.; Ruppert, K.; Hohlfeld, J.M.; Vogel-Claussen, J.
Zeitschriftenaufsatz
2019Repeatability of Regional Lung Ventilation Quantification Using Fluorinated (19F) Gas Magnetic Resonance Imaging
Gutberlet, M.; Kaireit, T.F.; Voskrebenzev, A.; Kern, A.L.; Obert, A.; Wacker, F.; Hohlfeld, J.M.; Vogel-Claussen, J.
Zeitschriftenaufsatz
2019RIFM fragrance ingredient safety assessment, [2-(cyclohexyloxy)ethyl]benzene, CAS Registry Number 80858-47-5
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A., Jr.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2019RIFM fragrance ingredient safety assessment, 1,2-dimethoxybenzene, CAS Registry Number 91-16-7
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2019RIFM fragrance ingredient safety assessment, 1,2-dimethoxybenzene, CAS Registry Number 91-16-7
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2019Sputum proteomic signature of gastro-oesophageal reflux in patients with severe asthma
Tariq, K.; Schofield, J.P.R.; Nicholas, B.L.; Burg, D.; Brandsma, J.; Bansal, A.T.; Wilson, S.J.; Lutter, R.; Fowler, S.J.; Bakke.; Caruso, M.; Dahlen, B.; Horvath, I.; Krug, N.; Montuschi, P.; Sanak, M.; Sandstrom, T.; Geiser, T.; Pandis, I.; Sousa, A.R.; Adcock, I.M.; Shaw, D.E.; Auffray, C.; Howarth, P.H.; Sterk, P.J.; Chung, K.F.; Skipp, P.J.; Dimitrov, B.; Djukanovic, R.
Zeitschriftenaufsatz
2019Surface defects reduce Carbon Nanotube toxicity in vitro
Requardt, H.; Braun, A.; Steinberg, P.; Hampel, S.; Hansen, T.
Zeitschriftenaufsatz
2019Targeted transcript quantification in single disseminated cancer cells after whole transcriptome amplification
Durst, F.C.; Grujovic, A.; Ganser, I.; Hoffmann, M.; Ugocsai, P.; Klein, C.A.; Czyz, Z.T.
Zeitschriftenaufsatz
2019Therapy resistance beyond cellular dormancy
Werner-Klein, M.; Klein, C.A.
Zeitschriftenaufsatz
2019Treatable traits in the European U-BIOPRED adult asthma cohorts
Simpson, A.J.; Hekking, P.-P.; Shaw, D.E.; Fleming, L.J.; Roberts, G.; Riley, J.H.; Bates, S.; Sousa, A.R.; Bansal, A.T.; Pandis, I.; Sun, K.; Bakke, P.S.; Caruso, M.; Dahlen, B.; Dahlen, S.-E.; Horvath, I.; Krug, N.; Montuschi, P.; Sandstrom, T.; Singer, F.; Adcock, I.M.; Wagers, S.S.; Djukanovic, R.; Chung, K.F.; Sterk, P.J.; Fowler, S.J.; Hohlfeld, J.M. et al.
Zeitschriftenaufsatz
2019Ultrafine particles and ozone perturb norepinephrine clearance rather than centrally generated sympathetic activity in humans
Heusser, K.; Tank, J.; Holz, O.; May, M.; Brinkmann, J.; Engeli, S.; Diedrich, A.; Framke, T.; Koch, A.; Großhennig, A.; Danser, A.H.J.; Sweep, F.C.G.J.; Schindler, C.; Schwarz, K.; Krug, N.; Jordan, J.; Hohlfeld, J.M.
Zeitschriftenaufsatz
2018Acute inhalation toxicity in vitro and ex vivo test battery prior to regulatory OECD 403 studies
Schwarz, Katharina; Hansen, Tanja; Ritter, Detlef; Walter, Dorothee; Knebel, Jan
Abstract
2018Air-liquid interface in vitro models for respiratory toxicology research: Consensus workshop and recommendations
Lacroix, Ghislaine; Koch, Wolfgang; Ritter, Detlef; Gutleb, Arno C.; Larsen, Søren Thor; Loret, Thomas; Zanetti, Filippo; Constant, Samuel; Chortarea, Savvina; Rothen-Rutishauser, Barbara M.; Hiemstra, Pieter S.; Frejafon, Emeric; Hubert, Philippe; Gribaldo, Laura; Kearns, Peter; Aublant, Jean-Marc; Diabaté, Silvia; Weiss, Carsten; Groot, Antoinette de; Kooter, Ingeborg
Zeitschriftenaufsatz
2018Airway and systemic inflammatory responses to ultrafine carbon black particles and ozone in older healthy subjects
Holz, Olaf; Heusser, Karsten; Müller, Meike; Windt, Horst; Schwarz, Katharina; Schindler, Christoph; Tank, Jens; Hohlfeld, Jens M.; Jordan, Jens
Zeitschriftenaufsatz
2018Alpha-1 antitrypsin inhibits ATP-mediated release of interleukin-1β via CD36 and nicotinic acetylcholine receptors
Siebers, Kathrin; Fink, Bijan; Zakrzewicz, Anna; Agné, Alisa; Richter, Katrin; Konzok, Sebastian; Hecker, Andreas; Zukunft, Sven; Küllmar, Mira; Klein, Jochen; McIntosh, J. Michael; Timm, Thomas; Sewald, Katherina; Padberg, Winfried; Aggarwal, Nupur; Chamulitrat, Walee; Santoso, Sentot; Xia, Wendy; Janciauskiene, Sabina; Grau, Veronika
Zeitschriftenaufsatz
2018An apoplastic peptide activates salicylic acid signalling in maize
Ziemann, Sebastian; Linde, Karina van der; Lahrmann, Urs; Acar, Beyda; Kaschani, Farnusch; Colby, Tom; Kaiser, Markus; Ding, Yezhang; Schmelz, Eric; Huffaker, Alisa; Holton, Nicholas; Zipfel, Cyril; Doehlemann, Gunther
Zeitschriftenaufsatz
2018The application of new HARD-descriptor available from the CORAL software to building up NOAEL models
Toropova, Alla P.; Toropov, Andrey A.; Marzo, Marco; Escher, Sylvia E.; Dorne, Jean Lou; Georgiadis, Nikolaos; Benfenati, Emilio
Zeitschriftenaufsatz
2018Approaches on MWCNT diameters and its relation to tumor development
Schwotzer, Daniela; Meyer-Plath, Asmus; Rittinghausen, Susanne; Creutzenberg, Otto H.; Leonhardt, Albrecht; Schaudien, Dirk
Abstract
2018Assessment of the cytotoxic and immunomodulatory effects of substances in human precision-cut lung slices
Neuhaus, Vanessa; Danov, Olga; Konzok, Sebastian; Obernolte, Helena; Dehmel, Susann; Braubach, Peter; Jonigk, Danny; Fieguth, Hans-Gerd; Zardo, Patrick; Warnecke, Gregor; Martin, Christian; Braun, Armin; Sewald, Katherina
Zeitschriftenaufsatz
2018Atemgesteuerte Applikation von pulverförmigen Aerosol bei der Beatmung oder Atemunterstützung eines Patienten
Iwaschenko, Peter; Pohlmann, Gerhard; Wiegandt, Felix
Patent
2018B cells control maternofetal priming of allergy and tolerance in a murine model of allergic airway inflammation
Happle, Christine; Jirmo, Adan Chari; Meyer-Bahlburg, Almut; Habener, Anika; Hoymann, Heinz-Gerd; Hennig, Christian; Skuljec, Jelena; Hansen, Gesine
Zeitschriftenaufsatz
2018Best practice approach for assessment of microchip-associated tumors in preclinical safety studies: Position of the Registry of Industrial Toxicology Animal-data (RITA)
Lapp, Stefanie; Bube, Axel; Colbatzky, Florian A.; Ernst, Heinrich; Kellner, Rupert; Nolte, Thomas; Rinke, Matthias
Zeitschriftenaufsatz
2018Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections
Ackermann, Mania; Kempf, Henning; Hetzel, Miriam; Hesse, Christina; Hashtchin, Anna Rafiei; Brinkert, Kerstin; Schott, Juliane Wilhelmine; Haake, Kathrin; Kühnel, Mark Philipp; Glage, Silke; Figueiredo, Constanca; Jonigk, Danny; Sewald, Katherina; Schambach, Axel; Wronski, Sabine; Moritz, Thomas; Martin, Ulrich; Zweigerdt, Robert; Munder, Antje; Lachmann, Nico
Zeitschriftenaufsatz
2018Breath volatile organic compounds of lung transplant recipients with and without chronic lung allograft dysfunction
Küppers, L.; Holz, Olaf; Schuchardt, Sven; Gottlieb, J.; Fuge, J.; Greer, M.; Hohlfeld, Jens M.
Zeitschriftenaufsatz
2018Carbon nanotube-silicone rubber on active thin-film implants
Behrens, Ailke; Foremny, Katharina; Doll, Theodor
Zeitschriftenaufsatz
2018Cerium oxide and barium sulfate nanoparticle inhalation affects gene expression in alveolar epithelial cells type II
Schwotzer, Daniela; Niehof, Monika; Schaudien, Dirk; Kock, Heiko; Hansen, Tanja; Dasenbrock, Clemens; Creutzenberg, Otto H.
Zeitschriftenaufsatz
2018Challenges in characterizing the environmental fate and effects of carbon nanotubes and inorganic nanomaterials in aquatic systems
Laux, Peter; Riebeling, Christian; Booth, Andy M.; Brain, Joseph D.; Brunner, Josephine; Cerrillo, Cristina; Creutzenberg, Otto H.; Estrela-Lopis, Irina; Gebel, Thomas; Johanson, Gunnar; Jungnickel, Harald; Kock, Heiko; Tentschert, Jutta; Tlili, Ahmed; Schäffer, Andreas; Sips, Adriënne J.A.M.; Yokel, Robert A.; Luch, Andreas
Zeitschriftenaufsatz
2018Characterization of human precision cut liver slices by various viability andfunctional parameters during 24 hour culture
Elenschneider, Leroy; Knebel, Jan; Braun, Armin; Fangmann, J.; Hansen, Tanja
Abstract
2018A combination of in-vitro and ex-vivo test models as an upstream alternative to regulatory OECD 403 animal studies
Walter, Dorothee; Ritter, Detlef; Knebel, Jan; Schwarz, Katharina; Hansen, Tanja
Abstract
2018Comparative proteomic analysis of hepatic effects induced by nanosilver, silver ions and nanoparticle coating in rats
Juling, Sabine; Böhmert, Linda; Lichtenstein, Dajana; Oberemm, Axel; Creutzenberg, Otto H.; Thünemann, Andreas F.; Braeuning, Albert; Lampen, Alfonso
Zeitschriftenaufsatz
2018Comparison of quantitative regional ventilation‐weighted fourier decomposition MRI with dynamic fluorinated gas washout MRI and lung function testing in COPD patients
Kaireit, Till F.; Gutberlet, Marcel; Voskrebenzev, Andreas; Freise, Julia; Welte, Tobias; Hohlfeld, Jens M.; Wacker, Frank; Vogel-Claussen, Jens
Zeitschriftenaufsatz
2018A comprehensive way to rate sputum quality in clinical trials
Pedersen, Frauke; Zissler, U.; Watz, Henrik; Rabe, Klaus F.; Hohlfeld, Jens M.; Holz, Olaf
Abstract
2018A computational framework for complex disease stratification from multiple large-scale datasets
Meulder, Bertrand de; Lefaudeux, Diane; Bansal, Aruna T.; Mazein, Alexander; Chaiboonchoe, Amphun; Ahmed, Hassan; Balaur, Irina; Saqi, Mansoor; Pellet, Johann; Ballereau, Stephane; Lemonnier, Nathanaël; Sun, Kai; Pandis, Ioannis; Yang, Xian; Batuwitage, Manohara; Kretsos, Kosmas; Eyll, Jonathan van; Bedding, Alun; Davison, Timothy; Dodson, Paul; Larminie, Christopher; Postle, Anthony; Corfield, Julie; Djukanović, Ratko; Chung, Kian Fan; Adcock, Ian M.; Guo, Yi-Ke; Sterk, Peter J.; Manta, Alexander; Rowe, Anthony; Baribaud, Frédéric; Auffray, Charles; Badorrek, Philipp; Faulenbach, Cornelia; Braun, Armin; Hohlfeld, Jens; Krug, Norbert
Zeitschriftenaufsatz
2018Cytotoxicity testing of therapeutic nanosystems for pulmonary infection using an air-lifted interphase in-vitro test system
Knebel, Jan W.; Ritter, Detlef; Niehof, Monika; Hansen, Tanja; Strandh, M.; Falciani, C.; Flores, M.; Welscher, Y. te; Nostrum, C. van; Gracia, R.; Marradi, M.; Loinaz, I.
Abstract
2018Development and evaluation of an in vitro test system for toxicity screening of aerosols released from consumer products and first application to aerosols from a hair straightening process
Ritter, Detlef; Bitsch, Annette; Elend, Manfred; Schuchardt, Sven; Hansen, Tanja; Brodbeck, Carsten; Knebel, Jan; Fuchs, Anne; Gronewold, Claas; Fautz, Rolf
Zeitschriftenaufsatz
2018Development of a novel scoring system for identifying emerging chemical risks in the food chain
Oltmanns, J.; Licht, O.; Bitsch, A.; Bohlen, M.-L.; Escher, S.E.; Silano, V.; Macleod, M.; Serafimova, R.; Kass, G.E.N.; Merten, C.
Zeitschriftenaufsatz
2018Development of an updated carcinogenicity potency database and analysis of thresholds of toxicological concern
Cronin, M.T.D.; Belfield, S.; Escher, Sylvia E.; Firman, J.; Liu, J.; Marsaux, C.; Mostrag-Szlichtyng, A.; Przybylak, K.; Rathman, J.; Tarkhov, Aleksey; Yang, C.
Abstract
2018Dezellularisierte Implantathüllen
Doll, Theodor; Pohlmann, Gerhard; Sieghorst, Jan
Patent
2018Diagnostic pathology of early systemic cancer: ERBB2 gene amplification in single disseminated cancer cells determines patient survival in operable esophageal cancer
Hoffmann, Martin; Pasch, Sophie; Schamberger, Thomas; Maneck, Matthias; Möhlendick, Birte; Schumacher, Sarah; Brockhoff, Gero; Knoefel, Wolfram Trudo; Izbicki, Jakob; Polzer, Bernhard; Stoecklein, Nikolas H.; Klein, Christoph A.
Zeitschriftenaufsatz
2018Effect of lung deflation with indacaterol plus glycopyrronium on ventricular filling in patients with hyperinflation and COPD (CLAIM): A double-blind, randomised, crossover, placebo-controlled, single-centre trial
Hohlfeld, Jens M.; Vogel-Claussen, Jens; Biller, Heike; Berliner, Dominik; Berschneider, Korbinian; Tillmann, Hanns-Christian; Hiltl, Simone; Bauersachs, Johann; Welte, Tobias
Zeitschriftenaufsatz
2018Engystol reduces onset of experimental respiratory syncytial virus-induced respiratory inflammation in mice by modulating macrophage phagocytic capacity
Wronski, Sabine; Dannenmaier, Julia; Schild, Sabine; Macke, Olaf; Müller, Laura; Burmeister, Yvonne; Seilheimer, Bernd; Müller, Meike
Zeitschriftenaufsatz
2018Enhanced oxidative stress in smoking and ex-smoking severe asthma in the U-BIOPRED cohort
Emma, Rosalia; Bansal, Aruna T.; Kolmert, Johan; Wheelock, Craig E.; Dahlén, Sven-Erik; Loza, Matthew J.; Meulder, Bertrand de; Lefaudeux, Diane; Auffray, Charles; Dahlén, Barbro; Bakke, Per S.; Chanez, Pascal; Fowler, Stephen J.; Horvath, Ildiko; Montuschi, Paolo; Krug, Norbert; Sanak, Marek; Sandström, Thomas; Shaw, Dominick E.; Fleming, Louise J.; Djukanovic, Ratko; Howarth, Peter H.; Singer, Florian; Sousa, Ana R.; Sterk, Peter J.; Corfield, Julie; Pandis, Ioannis; Chung, Kian F.; Adcock, Ian M.; Lutter, René; Fabbella, Lorena; Caruso, Massimo
Zeitschriftenaufsatz
2018Entwicklung einer Logistikkonzeption für eine dezentrale Fertigung von medizinischen Prüfprodukten
Abt, Felix
: Kopp, Harald (Betreuer); Diemar, Ute (Betreuer)
Master Thesis
2018EUToxRisk case studies: new approach methodologies in read-across
Escher, Sylvia E.
Abstract
2018Evaluation of the dose-response and fate in the lung and pleura of chrysotile containing brake dust compared to chrysotile or crocidolite asbestos in a 28 day inhalation toxicology study
Tóth, B.; Bernstein, David M.; Rogers, R.A.; Kunzendorf, Peter; Ernst, Heinrich
Abstract
2018Evaluation of the dose-response and fate in the lung and pleura of chrysotile containing brake dust compared to chrysotile or crocidolite asbestos in a 28-day inhalation toxicology study
Bernstein, D.M.; Tóth, B.; Rogers, R.A.; Kunzendorf, P.; Ernst, Heinrich
Abstract
2018Evaluation of the dose-response and fate in the lung and pleura of chrysotile-containing brake dust compared to chrysotile or crocidolite asbestos in a 28-day quantitative inhalation toxicology study
Bernstein, D.M.; Tóth, B.; Rogers, R.A.; Sepulveda, R.; Kunzendorf, P.; Phillips, J.I.; Ernst, Heinrich
Zeitschriftenaufsatz
2018Evaluierung der ökotoxikologischen Risikobewertung für genmodifizierte Arzneimittel
Weber, Elena
: Illing, Gerhard (1. Gutachter); Weigt, Henning (2. Gutachter)
Master Thesis
2018EXITOX-II: Development of an animal free testing strategy for the risk assessment of inhalable compounds
Escher, Sylvia E.; Tluczkiewicz, Inga; Hansen, Tanja; Niehof, Monika; Knebel, Jan; Ritter, Detlef; Danov, Olga; Obernolte, Helena; Schramm, Sinja-Fee; Koschmann, Jeannette; Kel, Alexander; Wingender, Edgar; Meckbach, Cornelia; Boomgarden, Wolfgang; Sewald, Katherina
Abstract
2018Flexible high density active neural implants combining a distributed multiplexing transceiver architecture with biocompatible technology
Marcoleta, Juan Pablo; Nogueira, Waldo; Froriep, Ulrich Paul; Doll, Theodor
Zeitschriftenaufsatz
2018Fraunhofer-Institut für Toxikologie und Experimentelle Medizin. Leistungen und Ergebnisse. Jahresbericht 2017
: Nastevska, Cathrin (Red.); Schlemminger, Karin (Übers.)
Jahresbericht
2018Fraunhofer-Institute for Toxicology and Experimental Medicine. Performance and Results. Annual Report 2017
: Nastevska, Cathrin (Red.); Schlemminger, Karin (Übers.)
Jahresbericht
2018Free-breathing dynamic (19)F gas MR imaging for mapping of regional lung ventilation in patients with COPD
Gutberlet, Marcel; Kaireit, Till F.; Voskrebenzev, Andreas; Lasch, Florian; Freise, Julia; Welte, Tobias; Wacker, Frank; Hohlfeld, Jens M.; Vogel-Claussen, Jens
Zeitschriftenaufsatz
2018A GATA3-specific DNAzyme attenuates sputum eosinophilia in eosinophilic COPD patients: A feasibility randomized clinical trial
Greulich, Timm; Hohlfeld, Jens M.; Neuser, Petra; Lueer, Katrin; Klemmer, Andreas; Schade-Brittinger, Carmen; Harnisch, Susanne; Garn, Holger; Renz, Harald; Homburg, Ursula; Renz, Jonas; Kirsten, Anne; Pedersen, Frauke; Müller, Meike; Vogelmeier, Claus F.; Watz, Henrik
Zeitschriftenaufsatz
2018Gene network analysis of interstitial macrophages after treatment with induced pluripotent stem cells secretome (iPSC-cm) in the bleomycin injured rat lung
Tamò, Luca; Simillion, Cedric; Hibaoui, Yousse; Feki, Anis; Gugger, Mathias; Prasse, Antje; Jäger, Benedikt; Goldmann, Torsten; Geiser, Thomas; Gazdhar, Amiq
Zeitschriftenaufsatz
2018Genetic alterations driving metastatic colony formation are acquired outside of the primary tumour in melanoma
Werner-Klein, Melanie; Scheitler, Sebastian; Hoffmann, Martin; Hodak, Isabelle; Dietz, Klaus; Lehnert, Petra; Naimer, Veronika; Polzer, Bernhard; Treitschke, Steffi; Werno, Christian; Markiewicz, Aleksandra; Weidele, Kathrin; Czyz, Zbigniew; Hohenleutner, Ulrich; Hafner, Christian; Haferkamp, Sebastian; Berneburg, Mark; Rümmele, Petra; Ulmer, Anja; Klein, Christoph A.
Zeitschriftenaufsatz
2018Genotoxic and mutagenic potential of camphorquinone in L5178/TK(+/-) mouse lymphoma cells
Volk, Joachim; Ziemann, Christina; Leyhausen, Gabriele; Geurtsen, Werner
Zeitschriftenaufsatz
2018German guideline for idiopathic pulmonary fibrosis - update on pharmacological therapies 2017
Behr, Jürgen; Günther, Andreas; Bonella, Francesco; Geißler, Klaus; Koschel, Dirk; Kreuter, Michael; Prasse, Antje; Schönfeld, Nicolas; Sitter, Helmut; Müller-Quernheim, Joachim; Costabel, Ulrich
Zeitschriftenaufsatz
2018High throughput adaptive stress response pathway activation to support read across of valproic acid analogue-induced liver steatosis
Vrijenhoek, N.G.; Gräpel, Rabea; Wink, S.; Escher, Sylvia E.; Water, Bob van de
Abstract
2018High-throughput microscopy of adaptive stress response pathway activation by steatosis-inducing valproic acid analogues
Vrijenhoek, N.G.; Gräpel, Rabea; Escher, Sylvia E.; Water, Bob van de
Abstract
2018Human airway mucus alters susceptibility of Pseudomonas aeruginosa biofilms to tobramycin, but not colistin
Müller, Laura; Murgia, Xabier; Siebenburger, Lorenz; Börger, Carsten; Schwarzkopf, Konrad; Sewald, Katherina; Häussler, Susanne; Braun, Armin; Lehr, Claus-Michael; Hittinger, Marius; Wronski, Sabine
Zeitschriftenaufsatz
2018Human lung tissue provides highly relevant data about efficacy of new anti-asthmatic drugs
Danov, Olga; Jiménez Delgado, Sharon Melissa; Obernolte, Helena; Seehase, Sophie; Dehmel, Susann; Braubach, Peter; Fieguth, Hans-Gerd; Matschiner, Gabriele; Fitzgerald, Mary; Jonigk, Danny; Knauf, Sascha; Pfennig, Olaf; Warnecke, Gregor; Wichmann, Judy; Braun, Armin; Sewald, Katherina
Zeitschriftenaufsatz
2018Human teratoma-derived hematopoiesis is a highly polyclonal process supported by human umbilical vein endothelial cells
Philipp, Friederike; Selich, Anton; Rothe, Michael; Hoffmann, Dirk; Rittinghausen, Susanne; Morgan, Michael A.; Klatt, Denise; Glage, Silke; Lienenklaus, Stefan; Neuhaus, Vanessa; Sewald, Katherina; Braun, Armin; Schambach, Axel
Zeitschriftenaufsatz
2018ICONS - Integrated testing strategy for mechanistically assessing the respiratory toxicity of functionalized MWCNTs - Comparative in vitro investigations
Ziemann, Christina; Reamon-Buettner, Stella Marie; Lison, Dominique; Bonner, J.C.; Brûle, Sybille van den; Simon, S.; Creutzenberg, Otto H.
Abstract
2018Identification and prospective stability of electronic nose (eNose) - derived inflammatory phenotypes in patients with severe asthma
Brinkman, P.; Wagener, A.H.; Hekking, P.-P.; Bansal, A.T.; Zee, A.-H. Maitland-van der; Wang, Y.; Weda, H.; Knobel, H.H.; Vink, T.J.; Rattray, N.J.; D'Amico, A.; Pennazza, G.; Santonico, M.; Lefaudeux, D.; Meulder, B. de; Auffray, C.; Bakke, P.S.; Caruso, M.; Chanez, P.; Chung, K.F.; Corfield, J.; Dahlén, S.-E.; Djukanovic, R.; Geiser, T.; Horvath, I.; Krug, N.; Musial, J.; Sun, K.; Riley, J.H.; Shaw, D.E.; Sandström, T.; Sousa, A.R.; Montuschi, P.; Fowler, S.J.; Sterk, P.J.
Zeitschriftenaufsatz
2018An immune cell spray (ICS) formulation allows for the delivery of functional monocyte/macrophages
Beneke, Valerie; Küster, Fennja; Neehus, Anna-Lena; Hesse, Christina; Lopez-Rodriguez, Elena; Haake, Kathrin; Rafiei Hashtchin, Anna; Schott, Juliane Wilhelmine; Walter, Dorothee; Braun, Armin; Wolkers, Willem F.; Ackermann, Mania; Lachmann, Nico
Zeitschriftenaufsatz
2018Impaired IFNγ-signaling and mycobacterial clearance in IFNγR1-deficient human iPSC-derived macrophages
Neehus, Anna-Lena; Lam, Jenny; Haake, Kathrin; Merkert, Sylvia; Schmidt, Nico; Mucci, Adele; Ackermann, Mania; Schubert, Madline; Happle, Christine; Kühnel, Mark Philipp; Blank, Patrick; Philipp, Friederike; Goethe, Ralph; Jonigk, Danny; Martin, Ulrich; Kalinke, Ulrich; Baumann, Ulrich; Schambach, Axel; Roesler, Joachim; Lachmann, Nico
Zeitschriftenaufsatz
2018Importance of the IL-1 axis in haemophilus influenzae-stimulated M1 macrophages driving transepithelial signaling
Mang, Samuel; Braun, Armin; Pairet, Nicolas; Lamb, David J.
Zeitschriftenaufsatz
2018Ein importierter Fall von feliner Leishmaniose in Deutschland und eine Literaturübersicht zur felinen Leishmaniose
Zind, Laura; Troyke, Reiner; Turban, Kathrin; Schaudien, Dirk; Baumgärtner, Wolfgang; Hansmann, Florian
Zeitschriftenaufsatz
2018In depth analysis of selected cosmetic ingredients from the SkinAB database
Schmeinck, Sina; Bitsch, Annette; Genth, Harald
Abstract
2018In silico prediction of DILI: Extraction of histopathology data from preclinical toxicity studies of the eTOX database for new in silico models of hepatotoxicity
Amberg, A.; Anger, L.; Stolte, M.; Hemmerich, J.; Matter, H.; Fisk, L.; Tluczkiewicz, Inga; Pinto-Gil, K.; López-Massaguer, O.; Pastor, M.
Abstract
2018In silico prediction of DILI: extraction of histopathology data from preclinical toxicity studies of the eTOX database for new in silico models of hepatotoxicity
Sullivan, K.; Baker, N.; Cochrane, S.; Enoch, Steven J.; Ezendam, Janine; Patlewicz, G.; Roggen, Erwin L.; Settivari, R.; Sewald, Katherina
Abstract
2018In vitro to in vivo extrapolation of valproic acid hepatotoxicity: A biokinetic and physiologically based toxicokinetic informed approach
Fisher, C.P.; Hatley, O.; Vugt, B. van; Bois, F.; Escher, Sylvia E.; Gardner, Iain
Abstract
2018In-situ characterization of e-cigarette aerosols by 90°-light scattering of polarized light
Dunkhorst, Wilhelm; Lipowicz, Peter; Li, Weiling; Hux, Casey; Wang, Qiang; Koch, Wolfgang
Zeitschriftenaufsatz
2018Innenraumluftqualität in Verkehrsflugzeugen
Rosenberger, Wolfgang; Schuchardt, Sven; Baumstark-Khan, C.; Hahn, A.
Aufsatz in Buch
2018International consensus statement on allergy and rhinology: Allergic rhinitis
Wise, Sarah K.; Lin, Sandra Y.; Toskala, Elina; Orlandi, Richard R.; Akdis, Cezmi A.; Alt, Jeremiah A.; Azar, Antoine; Baroody, Fuad M.; Bachert, Claus; Canonica, G. Walter; Chacko, Thomas; Cingi, Cemal; Ciprandi, Giorgio; Corey, Jacquelynne; Cox, Linda S.; Creticos, Peter Socrates; Custovic, Adnan; Damask, Cecelia; DeConde, Adam; DelGaudio, John M.; Ebert, Charles S.; Eloy, Jean Anderson; Flanagan, Carrie E.; Fokkens, Wytske J.; Franzese, Christine; Gosepath, Jan; Halderman, Ashleigh; Hamilton, Robert G.; Hoffman, Hans Jürgen; Hohlfeld, Jens M.; Houser, Steven M.; Hwang, Peter H.; Incorvaia, Cristoforo; Jarvis, Deborah; Khalid, Ayesha N.; Kilpeläinen, Maritta; Kingdom, Todd T.; Krouse, Helene; Larenas-Linnemann, Desiree; Laury, Adrienne M.; Lee, Stella E.; Levy, Joshua M.; Luong, Amber U.; Marple, Bradley F.; McCoul, Edward D.; McMains, K. Christopher; Melén, Erik; Mims, James W.; Moscato, Gianna; Mullol, Joaquim; Nelson, Harold S.; Patadia, Monica; Pawankar, Ruby; Pfaar, Oliver; Platt, Michael P.;
Zeitschriftenaufsatz
2018Investigation into pulmonary absorption using a combination of the ex vivo model of isolated perfused rat lungs and a simple PK model
Schwarz, Katharina; Koch, Wolfgang; Walter, Dorothee
Abstract
2018Investigations on classification and mechanisms of MWCNT-Induced carcinogenicity
Schwotzer, Daniela; Schaudien, Dirk; Rittinghausen, Susanne; Meyer-Plath, Asmus; Eckert, V.; Leonhardt, A.; Creutzenberg, Otto H.; Gebel, Thomas
Abstract
2018Investigations on the Toxicity of CeO2 Nanoparticles after Subchronic Inhalation of Low Doses
 
Dissertation
2018Isolated aggregates of lymphoid cells in the inner bronchial wall in asthma patients
Tschernig, Thomas; Pabst, Reinhard; Prenzler, Frauke; Rittinghausen, Susanne; Braun, Armin; Hohlfeld, Jens M.
Zeitschriftenaufsatz
2018Isolated metastasis of an EGFR-L858R-mutated NSCLC of the meninges: The potential impact of CXCL12/CXCR4 axis in EGFRmut NSCLC in diagnosis, follow-up and treatment
Lüke, Florian; Blazquez, Raquel; Yamaci, Rezan Fahrioglu; Lu, Xin; Pregler, Benedikt; Hannus, Stefan; Menhart, Karin; Hellwig, Dirk; Wester, Hans-Jürgen; Kropf, Saskia; Heudobler, Daniel; Grosse, Jirka; Moosbauer, Jutta; Hutterer, Markus; Hau, Peter; Riemenschneider, Markus J.; Bayerlová, Michaela; Bleckmann, Annalen; Polzer, Bernhard; Beißbarth, Tim; Klein, Christoph A.; Pukrop, Tobias
Zeitschriftenaufsatz
2018Knotting nets. Molecular junctions of interconnecting endocrine axes identified by application of the adverse outcome pathway (AOP) concept
Brüggemann, Maria; Licht, Oliver; Fetter, Éva; Teigeler, Matthias; Schäfers, Christoph; Eilebrecht, Elke
Zeitschriftenaufsatz
2018Large-Scale Label-Free Quantitative Mapping of the Sputum Proteome
Burg, Dominic; Schofield, James P.R.; Brandsma, Joost; Staykova, Doroteya; Folisi, Caterina; Bansal, Aruna T.; Nicholas, Ben; Xian, Yang; Rowe, Anthony; Corfield, Julie; Wilson, Susan J.; Ward, Jonathan A.; Lutter, René; Fleming, Louise; Shaw, Dominick E.; Bakke, Per S.; Caruso, Massimo; Dahlén, Sven-Erik; Fowler, Stephen J.; Hashimoto, Simone; Horvath, Ildiko; Howarth, Peter; Krug, Norbert; Montuschi, Paolo; Sanak, Marek; Sandström, Thomas; Singer, Florian; Sun, Kai; Pandis, Ioannis; Auffray, Charles; Sousa, Ana R.; Adcock, Ian M.; Chung, Kian F.; Sterk, Peter J.; Djukanovic, Ratko; Skipp, Paul J.
Zeitschriftenaufsatz
2018Lipid phenotyping of lung epithelial lining fluid in healthy human volunteers
Brandsma, Joost; Goss, Victoria M.; Yang, Xian; Bakke, Per S.; Caruso, Massimo; Chanez, Pascal; Dahlén, Sven-Erik; Fowler, Stephen J.; Horváth, Ildikó; Krug, Norbert; Montuschi, Paolo; Sanak, Marek; Sandström, Thomas; Shaw, Dominick E.; Chung, Kian Fan; Singer, Florian; Fleming, Louise J.; Sousa, Ana R.; Pandis, Ioannis; Bansal, Aruna T.; Sterk, Peter J.; Djukanović, Ratko; Postle, Anthony D.
Zeitschriftenaufsatz
2018Low dose carbon black nanoparticle exposure does not aggravate allergic airway inflammation in mice irrespective of the presence of surface polycyclic aromatic hydrocarbons
Lindner, Karina; Webering, Sina; Ströbele, Michael; Bockhorn, Henning; Hansen, Tanja; König, Peter; Fehrenbach, Heinz
Zeitschriftenaufsatz
2018Low-energy electron beam sterilization for medical technical applications
Portillo, J.; Gotzmann, G.; Schönfelder, J.; Rögner, F.-H.; Wronski, S.; Müller, M.; Kohl, Y; Gorjup, E.
Konferenzbeitrag
2018Low-energy electron-beam treatment as alternative for on-site sterilization of highly functionalized medical products - a feasibility study
Gotzmann, G.; Portillo, J.; Wronski, S.; Kohl, Y; Gorjup, E.; Schuck, H.; Rögner, F.-H.; Müller, M.; Chaberny, I.F.; Schönfelder, J.; Wetzel, C.
Zeitschriftenaufsatz
2018Lymphoid Tissue and Pathological Influences of Toxicants
Schaudien, D.; Harleman, J.H.; Bouallala, F.; Kuper, C.F.
Aufsatz in Buch
2018Matrix metalloproteinases expression in spontaneous canine histiocytic sarcomas and its xenograft model
Fayyad, Adnan; Lapp, Stefanie; Risha, Engy; Pfankuche, Vanessa M.; Rohn, Karl; Barthel, Yvonne; Schaudien, Dirk; Baumgärtner, Wolfgang; Puff, Christina
Zeitschriftenaufsatz
2018Messgerät und Verfahren zum Betimmen einer maximalen Inhalationsleistung einer Person
Pohlmann, Gerhard; Ramazanoglu, Mehmet
Patent
2018Metallomics Study in Plants Exposed to Arsenic, Mercury, Selenium and Sulphur
Feldmann, Jörg; Blümlein, Katharina; Krupp, Eva Maria; Müller, Martin; Wood, Barry A.
Aufsatz in Buch
2018A methodology for the assessment of inhalation exposure to aluminium from antiperspirant sprays
Schwarz, Katharina; Pappa, Gerlinde; Miertsch, Heike; Scheel, Julia; Koch, Wolfgang
Zeitschriftenaufsatz
2018Mining the effector repertoire of the biotrophic fungal pathogen Ustilago hordei during host and non-host infection
Ökmen, Bilal; Mathow, Daniel; Hof, Alexander; Lahrmann, Urs; Aßmann, Daniela; Doehlemann, Gunther
Zeitschriftenaufsatz
2018Nanomaterials: Certain aspects of application, risk assessment and risk communication
Laux, Peter; Tentschert, Jutta; Riebeling, Christian; Braeuning, Albert; Creutzenberg, Otto; Epp, Astrid; Fessard, Valérie; Haas, Karl-Heinz; Haase, Andrea; Hund-Rinke, Kerstin; Jakubowski, Norbert; Kearns, Peter; Lampen, Alfonso; Rauscher, Hubert; Schoonjans, Reinhilde; Störmer, Angela; Thielmann, Axel; Mühle, Uwe; Luch, Andreas
Zeitschriftenaufsatz
2018New thin-film surface electrode array enables brain mapping with high spatial acuity in rodents
Konerding, W. S.; Froriep, Ulrich P.; Kral, A.; Baumhoff, P.
Zeitschriftenaufsatz
2018Nonproliferative and proliferative lesions of the rat and mouse endocrine system
Brändli-Baiocco, Annamaria; Balme, Emmanuelle; Bruder, Marc; Chandra, Sundeep; Hellmann, Jürgen; Hoenerhoff, Mark J.; Kambara, Takahito; Landes, Christian; Lenz, Barbara; Mense, Mark; Rittinghausen, Susanne; Satoh, Hiroshi; Schorsch, Frédéric; Seeliger, Frank; Tanaka, Takuji; Tsuchitani, Minoru; Wojcinski, Zbigniew; Rosol, Thomas J.
Zeitschriftenaufsatz
2018Nonproliferative and proliferative lesions of the ratand mouse special sense organs(Ocular [eye and glands], olfactory and otic)
Ramos, Meg Ferrell; Baker, Julia F.; Atzpodien, Elke-Astrid; Bach, Ute; Brassard, Jacqueline; Cartwright, James; Farman, Cynthia; Fishman, Cindy; Jacobsen, Matt; Junker-Walker, Ursula; Kuper, Frieke; Moreno, Maria Cecilia Rey; Rittinghausen, Susanne; Schafer, Ken; Tanaka, Kohji; Teixeira, Leandro; Yoshizawa, Katsuhiko; Zhang, Hui
Zeitschriftenaufsatz
2018A novel short L-arginine responsive protein-coding gene (laoB) antiparallel overlapping to a CadC-like transcriptional regulator in Escherichia coli O157:H7 Sakai originated by overprinting
Hücker, Sarah M.; Vanderhaeghen, Sonja; Abellan-Schneyder, Isabel; Wecko, Romy; Simon, Svenja; Scherer, Siegfried; Neuhaus, Klaus
Zeitschriftenaufsatz
2018Optimized protocol for the biocompatibility testing of compression stockings and similar products with close skin contact in vitro
Wiegand, C.; Hansen, T.; Köhnlein, J.; Exner, I.; Damisch-Pohl, M.; Schott, P.; Krühner-Wiesenberger, U.; Hipler, U.-C.; Pohlen, E.
Zeitschriftenaufsatz
2018Optogenetic entrainment of neural oscillations with hybrid fiber probes
Kilias, Antje; Canales, Andres; Froriep, Ulrich P.; Park, Seongjun; Egert, Ulrich; Anikeeva, Polina
Zeitschriftenaufsatz
2018Pathway discovery using transcriptomic profiles in adult-onset severe asthma
Hekking, Pieter-Paul; Loza, Matt J.; Pavlidis, Stelios; Meulder, Bertrand de; Lefaudeux, Diane; Baribaud, Fred; Auffray, Charles; Wagener, Ariane H.; Brinkman, Paul; Lutter, René; Bansal, Aruna T.; Sousa, Ana R.; Bates, Steve A.; Pandis, Yannis; Fleming, Louise J.; Shaw, Dominique E.; Fowler, Stephen J.; Guo, Y.; Meiser, Andrea; Sun, Kai; Corfield, Julie; Howarth, Peter H.; Bel, Elisabeth H.; Adcock, Ian M.; Chung, Kian Fan; Djukanović, Ratko; Sterk, Peter J.
Zeitschriftenaufsatz
2018Phase 1 pharmacokinetics and phase 3 efficacy of testosterone nasal gel in subjects with seasonal allergies
Rogol, Alan D.; Tkachenko, Natalia; Badorrek, Philipp; Hohlfeld, Jens M.; Bryson, Nathan
Zeitschriftenaufsatz
2018Phenotypic characterization of blood and lung ILC2 in asthmatics undergoing segmental allergen provocation
Pardali, Katerina; Winkler, Carla; Hochdorfer, T.; Cavallin, A.; Hasselberg, A.; Vaarala, O.; Müller, Meike; Lüer, Katrin
Abstract
2018Physiologisch basierte toxikokinetische (PBTK) Modellierung zur Aufnahme von Chemikalien/Aerosolen über die Lunge
Winkler, Daniel Sandro
: Escher, Sylvia E. (Betr.); Esch, Christina (Betr.)
Master Thesis
2018Platox in vitro and in vivo investigations (28-day inhalation) to generate valid toxicity data for risk assessment of carbon-based nanoplatelets
Creutzenberg, Otto H.; Ziemann, Christina; Oliveira, H.; Farcal, L.; Burla, S.
Abstract
2018The PLATOX project: Combining in vitro and in vivo investigations to generate valid toxicity data for risk assessment of graphene nanoplatelets
Creutzenberg, Otto H.; Ziemann, Christina; Schaudien, Dirk; Oliveira, Helena; Farcal, Lucian
Abstract
2018Prediction of microvesicular liver steatosis: a read-across case study with branched carboxylic acids
Escher, Sylvia E.; Tolosa Pardo, L.; Maclennan, R.; Stöber, R.; Limonciel, A.; Fisher, C.; Brotzmann, K.; Vugt-Lussenburg, B.M. van; Vrijenhoek, N.G.; Gräpel, R.
Abstract
2018Prenatal treatment with rosiglitazone attenuates vascular remodeling and pulmonary monocyte influx in experimental congenital diaphragmatic hernia
Gosemann, Jan-Hendrik; Friedmacher, Florian; Hofmann, Alejandro; Zimmer, Julia; Kuebler, Joachim F.; Rittinghausen, Susanne; Suttkus, Anne; Lacher, Martin; Alvarez, Luis; Corcionivoschi, Nicolae; Puri, Prem
Zeitschriftenaufsatz
2018Quantitative characterization of mixing in multicomponent nanoparticle aggregates
Baric, Valentin; Grossmann, Henrike Katharina; Koch, Wolfgang; Mädler, Lutz
Zeitschriftenaufsatz
2018Review of Tier 1 workplace exposure estimates for petroleum substances in REACH dossiers
Hesse, Susanne; Hahn, Stefan; Lamb, Judith; Basinas, Ioannis; Apsley, Andrew; Tongeren, Martie van; Urbanus, J.; Pizzella, G.; Banton, M.; Dudzina, T.; Tibaldi, R.; Geudens, B.; Jones, R.; Ketelslegers, H.; Trantallidi, M.
Bericht
2018RIFM fragrance ingredient safety assessment 2,4-dimethylbenzyl acetate, CAS Registry Number 62346-96-7
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment 2-Benzylheptanol, CAS Registry Number 92368-90-6
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment 2-methyl-trans-2-butenoic acid, CAS Registry Number 80-59-1
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment 5,8-Methano-2H-1-benzopyran-2-one, 6- ethylideneoctahydro-, CAS Registry Number 69486-14-2
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment β-Patchoulene, CAS Registry Number 514-51-2
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Dekant, W.; Fryer, A.D.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Wahler, J.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment benzyl 2,2-dimethylpropanoate, CAS Registry Number 2094-69-1
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment cyclohexanecarboxylic acid, CAS Registry Number 98-89-5
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment diethyl succinate, CAS Registry Number 123-25-1
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment dihydro-β-terpinyl acetate, CAS Registry Number 26252-11-9
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment Dimethyl succinate, CAS Registry Number 106-65-0
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2018RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT p-Methylanisole, CAS Registry Number 104-93-8
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; BruzE, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; DekanT, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; la Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment phenethyl isovalerate, CAS Registry Number 140-26-1
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2018RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT phenylethyl 2-methylbutyrate, CAS Registry Number 24817-51-4
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; Cava, S.L.A.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2018RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT, [2-Isopropoxyethyl]benzene, CAS Registry Number 68039-47-4
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, (Z)-4-hepten-1-ol, CAS Registry Number 6191-71-5
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, (Z)-Octadec-9-enol, CAS Registry Number 143-28-2
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, 1,1-diethoxyisooctane, CAS Registry Number 69178-43-4
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, 1,2,3,4,5,6,7,8,9,10-decahydro-5,9-methanobenzocycloocten-11-one, CAS Registry Number 22690-27-3
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, 1,3-Benzodioxole-5-propanol, α-methyl-, 5-acetate, CAS Registry Number 68844-96-2
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, 1,3-dimethylbut-3-enyl isobutyrate, CAS Registry Number 80118-06-5
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, 1-(3,3-dimethylbicyclo[2.2.1]hept-2-yl)ethane-1-one, CAS Registry Number 42370-07-0
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT, 1-Methyl-2-(1-methylpropyl)cyclohexyl acetate, CAS Registry Number 72183-75-6
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT, 1-Oxaspiro[4.5]decan-2-one, 8-(1-methylethyl)-, trans-, CAS Registry Number 4625-90-5
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, 1-oxaspiro[4.5]decan-2-one, 8-methyl-, CAS Registry Number 94201-19-1
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT, 2,6-Dimethylocta-2,4,6-triene, CAS Registry Number 673-84-7
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, 2-ethylhexyl acetate, CAS Registry Number 103-09-3
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, 2-Hexylcyclopentanone, CAS Registry Number 13074-65-2
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT, 2-Methyl-2-hepten-6-ol, CAS Registry Number 1569-60-4
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, 2-methylhexanoic acid, CAS Registry Number 4536-23-6
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, 2-methylundecanal dimethyl acetal, CAS Registry Number 68141-17-3
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, 2-Methylvaleric acid, CAS Registry Number 97-61-0
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM Fragrance ingredient safety assessment, 2-nonen-1-ol, CAS registry number 22104-79-6
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, 2H-Inden-2-one, 1,3-dihydro-, CAS Registry Number 615-13-4
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, 3-(cis-3-hexenyloxy)propanenitrile, CAS Registry Number 142653-61-0
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, 3-methyl-1-pentanol, CAS Registry Number 589-35-5
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, 3-methyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)pent-4-en-2-ol, CAS Registry Number 67801-20-1
Api, A.M.; Belsito, D.; Bhatia, S.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; Kromidas, L.; La Cava, S.; Lalko, J.F.; Lapczynski, A.; Liebler, D.C.; Miyachi, Y.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Politano, V.T.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.; Wall, B.; Wilcox, D.K.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, 3-Methylbutanal diethyl acetal, CAS Registry Number 3842-03-3
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, 3-tert-butylcyclohexyl acetate, CAS Registry Number 31846-06-7
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, 3a,4,5,6,7,7a-hexahydro-4,7-methano-1H-inden-5-yl pivalate, CAS Registry Number 68039-45-2
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, 4′-methylacetophenone, CAS Registry Number 122-00-9
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT, 4,8-Dimethyl-3-7-nonadien-2-ol, CAS Registry Number 67845-50-5
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, 4-Hexen-1-ol, (4Z)-, CAS Registry Number 928-91-6
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; Cava, S.L.A.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, 4-pentenoic acid, 2-acetyl-4-methyl-, ethyl ester, CAS Registry Number 20962-70-3
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, 5,9-undecadien-2-ol,6,10-dimethyl-,acetate, CAS Registry Number 91482-37-0
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, acetal, CAS Registry Number 105-57-7
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, acetophenone, CAS Registry Number 98-86-2
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, Amylcyclohexyl acetate (mixed isomers), CAS Registry Number 67874-72-0
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, β-caryophyllene alcohol, CAS Registry Number 472-97-9
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, benzyl formate, CAS Registry Number 104-57-4
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, benzyl isoamyl ether, CAS Registry Number 122-73-6
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, benzyl methyl ether, CAS Registry Number 538-86-3
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, bis(hydroxymethyl)tricyclo[5.2.1.02,6]decane, CAS Registry Number 26160-83-8
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT, butanoic acid, 3a,4,5,6,7,7a-hexahydro-4,7-methano-1H-indenyl ester, CAS Registry Number 113889-23-9
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT, Butyl phenylacetate, CAS Registry Number 122-43-0
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, butyrophenone, cas Registry Number 495-40-9
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, cis-3-octenyl propionate, CAS Registry Number 94134-03-9
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, cis-5-octen-1-ol CAS Registry Number 64275-73-6
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, dihydroterpinyl acetate, CAS registry number 58985-18-5
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, dodecanal dimethyl acetal, CAS Registry Number 14620-52-1
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, dodecanenitrile, CAS Registry Number 2437-25-4
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, endo-1,2,3,3-tetramethylbicyclo[2.2.1]heptan-2-ol, CAS Registry Number 28462-85-3
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, ethyl phenylacetate, CAS Registry Number 101-97-3
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, Fenchone, CAS Registry Number 1195-79-5
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, geranic acid, CAS Registry Number 459-80-3
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, heptanal dimethyl acetal, CAS Registry Number 10032-05-0
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, hexahydro-3H-benzofuran-2-one, CAS Registry Number 6051-03-2
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, Hexyl acetate, CAS Registry Number 142-92-7
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, hexyl benzoate, CAS Registry Number 6789-88-4
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, hexyl formate, CAS Registry Number 629-33-4
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, isobutyl benzoate, CAS registry number 120-50-3
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, isophorol, CAS Registry Number 470-99-5
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, l-menthyl lactate, CAS Registry Number 59259-38-0
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, methyl benzoate, CAS Registry Number 93-58-3
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM Fragrance ingredient safety assessment, methylheptenol, CAS Registry Number 1335-09-7
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, nonane, 1,1-diethoxy-, CAS Registry Number 54815-13-3
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, nonyl acetate, CAS Registry Number 143-13-5
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, octanal dimethyl acetal, CAS Registry Number 10022-28-3
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; Cava, S.L.A.; Lapczynski, A.; Liebler, D.C.; O'brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, octyl butyrate, CAS Registry Number 110-39-4
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, p-(2,2-dimethoxyethoxy)toluene, CAS Registry Number 6324-78-3
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, p-tert-butylacetophenone, CAS Registry Number 943-27-1
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, pentanedioic acid, 1,5-dimethyl ester, CAS Registry Number 1119-40-0
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, phenethyl tiglate, CAS Registry Number 55719-85-2
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, terpinyl acetate (isomer mixture), CAS Registry number 8007-35-0
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT, Terpinyl butyrate, CAS Registry Number 2153-28-8
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, terpinyl formate, CAS Registry Number 2153-26-6
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, terpinyl propionate, CAS Registry Number 80-27-3
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, trans-2-Hexenol, CAS Registry Number 928-95-0
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, tricyclodecanyl acetate, CAS Registry Number 64001-15-6
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018RIFM fragrance ingredient safety assessment, Valencene, CAS Registry Number 4630-07-3
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Zeitschriftenaufsatz
2018The sentinel lymph node spread determines quantitatively melanoma seeding to non-sentinel lymph nodes and survival
Ulmer, Anja; Dietz, Klaus; Werner-Klein, Melanie; Hafner, Hans-Martin; Schulz, Claudia; Renner, Philipp; Weber, Florian; Breuninger, Helmut; Röcken, Martin; Garbe, Claus; Fierlbeck, Gerhard; Klein, Christoph A.
Zeitschriftenaufsatz
2018Sicherheit im Umgang mit Nanomaterialien
Creutzenberg, Otto H.
Aufsatz in Buch
2018Signatures of T and B cell development, functional responses and PD-1 upregulation after HCMV latent infections and reactivations in Nod.Rag.Gamma mice humanized with cord blood CD34(+) cells
Theobald, Sebastian J.; Khailaie, Sahamoddin; Meyer-Hermann, Michael; Volk, Valery; Olbrich, Henning; Danisch, Simon; Gerasch, Laura; Schneider, Andreas; Sinzger, Christian; Schaudien, Dirk; Lienenklaus, Stefan; Riese, Peggy; Guzman, Carlos A.; Figueiredo, Constanca; Kaisenberg, Constantin von; Spineli, Loukia M.; Glaesener, Stephanie; Meyer-Bahlburg, Almut; Ganser, Arnold; Schmitt, Michael; Mach, Michael; Messerle, Martin; Stripecke, Renata
Zeitschriftenaufsatz
2018Single cell polarity in liquid phase facilitates tumour metastasis
Lorentzen, Anna; Becker, Paul F.; Kosla, Jan; Saini, Massimo; Weidele, Kathrin; Ronchi, Paolo; Klein, Corinna; Wolf, Monika J.; Geist, Felix; Seubert, Bastian; Ringelhan, Marc; Mihic-Probst, Daniela; Esser, Knud; Roblek, Marko; Kuehne, Felix; Bianco, Gaia; O'Connor, Tracy; Müller, Quentin; Schuck, Kathleen; Lange, Sebastian; Hartmann, Daniel; Spaich, Saskia; Gross, Olaf; Utikal, Jochen; Haferkamp, Sebastian; Sprick, Martin R.; Damle-Vartak, Amruta; Hapfelmeier, Alexander; Hüser, Norbert; Protzer, Ulrike; Trumpp, Andreas; Saur, Dieter; Vartak, Nachiket; Klein, Christoph A.; Polzer, Bernhard; Borsig, Lubor; Heikenwalder, Mathias
Zeitschriftenaufsatz
2018Solvent transfer - efficiency of risk management measures
Blümlein, Katharina; Elend, Manfred; Meijster, Tim; Margary, Alison; Tibaldi, Rosalie; Hahn, Stefan; Hesse, Susanne
Zeitschriftenaufsatz
2018Sputum proteomics and airway cell transcripts of current and ex-smokers with severe asthma in U-BIOPRED: An exploratory analysis
Takahashi, Kentaro; Pavlidis, Stelios; Ng Kee Kwong, Francois; Hoda, Uruj; Rossios, Christos; Sun, Kai; Loza, Matthew; Baribaud, Fred; Chanez, Pascal; Fowler, Steve J.; Horvath, Ildiko; Montuschi, Paolo; Singer, Florian; Musial, Jacek; Dahlén, Barbro; Dahlén, Sven-Erik; Krug, Norbert; Sandström, Thomas; Shaw, Dominick E.; Lutter, René; Bakke, Per; Fleming, Louise J.; Howarth, Peter H.; Caruso, Massimo; Sousa, Ana R.; Corfield, Julie; Auffray, Charles; Meulder, Bertrand de; Lefaudeux, Diane; Djukanovic, Ratko; Sterk, Peter J.; Guo, Yike; Adcock, Ian M.; Chung, Kian Fan
Zeitschriftenaufsatz
2018Stochastic system identification without an a priori chosen kinetic model - exploring feasible cell regulation with piecewise linear functions
Hoffmann, Martin; Galle, Jörg
Zeitschriftenaufsatz
2018Target cell pre-enrichment and whole genome amplification for single cell downstream characterization
Chen, Shukun; El-Heliebi, Amin; Schmid, Julia; Kashofer, Karl; Czyz, Zbigniew T.; Polzer, Bernhard Michael; Pantel, Klaus; Kroneis, Thomas; Sedlmayr, Peter
Zeitschriftenaufsatz
2018Targeting the senescence-overriding cooperative activity of structurally unrelated H3K9 demethylases in melanoma
Yu, Yong; Schleich, Kolja; Yue, Bin; Ji, Sujuan; Lohneis, Philipp; Kemper, Kristel; Silvis, Mark S.; Qutob, Nouar; Rooijen, Ellen van; Werner-Klein, Melanie; Li, Lianjie; Dhawan, Dhriti; Meierjohann, Svenja; Reimann, Maurice; Elkahloun, Abdel; Treitschke, Steffi; Dörken, Bernd; Speck, Christian; Mallette, Frederick A.; Zon, Leonard I.; Holmen, Sheri L.; Peeper, Daniel S.; Samuels, Yardena; Schmitt, Clemens A.; Lee, Soyoung
Zeitschriftenaufsatz
2018TMPRSS11A activates the influenza A virus hemagglutinin and the MERS coronavirus spike protein and is insensitive against blockade by HAI-1
Zmora, Pawel; Hoffmann, Markus; Kollmus, Heike; Moldenhauer, Anna-Sophie; Danov, Olga; Braun, Armin; Winkler, Michael; Schughart, Klaus; Pöhlmann, Stefan
Zeitschriftenaufsatz
2018Toxicogenomics directory of rat hepatotoxicants in vivo and in cultivated hepatocytes
Grinberg, Marianna; Stöber, Regina M.; Albrecht, Wiebke; Edlund, Karolina; Schug, Markus; Godoy, Patricio; Cadenas, Cristina; Marchan, Rosemarie; Lampen, Alfonso; Braeuning, Albert; Buhrke, Thorsten; Leist, Marcel; Oberemm, Axel; Hellwig, Birte; Kamp, Hennicke; Gardner, Iain; Escher, Sylvia E.; Taboureau, Olivier; Aguayo-Orozco, Alejandro; Sachinidis, Agapios; Ellinger-Ziegelbauer, Heidrun; Rahnenfuhrer, Jörg; Hengstler, Jan G.
Zeitschriftenaufsatz
2018Der Umgang mit Forschungsdaten, im Kontext der Open Research Anforderungen, an außeruniversitären Forschungseinrichtungen – am Beispiel des Fraunhofer-Instituts für Toxikologie und Experimentelle Medizin (ITEM) als Teil der Fraunhofer-Gesellschaft
Wiedemeier, Petra
: Horstmann, Wolfram (1. Gutachter); Weigt, Henning (2. Gutachter)
Master Thesis
2018Untersuchungen zum zytotoxischen, gentoxischen und pro-inflammatorischen Potential von Graphen-Nanoplättchen in Rattenalveolarmakrophagen
Gripp, Tatjana
: Noll, Thomas (1. Gutachter); Ziemann, Christina (2. Gutachter)
Master Thesis
2018Use of new approach methods to support chemical read-across: The EU-ToxRisk experience
Water, Bob van de; Kamp, Hennicke; Escher, Sylvia E.; Kroese, Dinant
Abstract
2017Additives for reducing the toxicity of respirable crystalline silica. SILIFE project
Monfort, E.; López-Lilao, A.; Escrig, A.; Ibanez, M.J.; Bonvicini, G.; Creutzenberg, O.; Ziemann, C.
Konferenzbeitrag
2017An Adverse Outcome Pathway for Sensitization of the Respiratory Tract by Low-Molecular-Weight Chemicals
Sullivan, K.M.; Enoch, S.J.; Ezendam, J.; Sewald, K.; Roggen, E.L.; Cochrane, S.
Zeitschriftenaufsatz
2017Adverse outcome pathways: Opportunities, limitations and open questions
Leist, M.; Ghallab, A.; Graepel, R.; Marchan, R.; Hassan, R.; Bennekou, S.H.; Limonciel, A.; Vinken, M.; Schildknecht, S.; Waldmann, T.; Danen, E.; Ravenzwaay, B. van; Kamp, H.; Gardner, I.; Godoy, P.; Bois, F.Y.; Braeuning, A.; Reif, R.; Oesch, F.; Drasdo, D.; Höhme, S.; Schwarz, M.; Hartung, T.; Braunbeck, T.; Beltman, J.; Vrieling, H.; Sanz, F.; Forsby, A.; Gadaleta, D.; Fisher, C.; Kelm, J.; Fluri, D.; Ecker, G.; Zdrazil, B.; Terron, A.; Jennings, P.; Burg, B. van der; Dooley, S.; Meijer, A.H.; Willighagen, E.; Martens, M.; Evelo, C.; Mombelli, E.; Taboureau, O.; Mantovani, A.; Hardy, B.; Koch, B.; Escher, S.; Thriel, C. van; Cadenas, C.; Kroese, D.; Water, B. van de; Hengstler, J.G.
Zeitschriftenaufsatz
2017Allergen exposure chambers: harmonizing current concepts and projecting the needs for the future - an EAACI Position Paper
Pfaar, O.; Calderon, M.A.; Andrews, C.P.; Angjeli, E.; Bergmann, K.C.; Bonlokke, J.H.; Blay, F. de; Devillier, P.; Ellis, A.K.; Wijk, R.G. van; Hohlfeld, J.M.; Horak, F.; Jacobs, R.L.; Jacobsen, L.; Jutel, M.; Kaul, S.; Larche, M.; Larenas-Linnemann, D.; Mosges, R.; Nolte, H.; Patel, P.; Peoples, L.; Rabin, R.L.; Rather, C.; Salapatek, A.M.; Sigsgaard, T.; Thaarup, S.; Yang, J.; Zieglmayer, P.; Zuberbier, T.; Demoly, P.
Zeitschriftenaufsatz
2017Anti-viral and inflammatory host response to rhinovirus is induced in vital ex vivo human lung tissue and reduced by anti-viral treatments
Obernolte, H.; Braubach, P.; Jonigk, D.; Kruger, M.; Warnecke, G.; Pfennig, O.; Fieguth, H.-G.; Braun, A.; Sewald, K.; Wronski, S.
Abstract
2017Antibiotic mixture effects on growth of the leaf-shredding stream detritivore Gammarus fossarum
Bundschuh, Mirco; Hahn, Torsten; Gessner, Mark O.; Schulz, Ralf
Zeitschriftenaufsatz
2017Aseptische Abfüllung biopharmazeutischer Prüfarzneimittel
Baydoun, Luma; Ziehr, Holger
Zeitschriftenaufsatz
2017Assessment of long-term cultivated human precision-cut lung slices as an ex vivo system for evaluation of chronic cytotoxicity and functionality
Neuhaus, V.; Schaudien, D.; Golovina, T.; Temann, U.-A.; Thompson, C.; Lippmann, T.; Bersch, C.; Pfennig, O.; Jonigk, D.; Braubach, P.; Fieguth, H.-G.; Warnecke, G.; Yusibov, V.; Sewald, K.; Braun, A.
Zeitschriftenaufsatz
2017Between-User Reliability of Tier 1 Exposure Assessment Tools Used Under REACH
Lamb, J.; Galea, K.S.; Miller, B.G.; Hesse, S.; Tongeren, M. van
Zeitschriftenaufsatz
2017Biokinetics of nanomaterials. The role of biopersistence
Laux, Peter; Riebeling, Christian; Booth, Andy M.; Brain, Joseph D.; Brunner, Josephine; Cerrillo, Cristina; Creutzenberg, Otto H.; Estrela-Lopis, Irina; Gebel, Thomas; Johanson, Gunnar; Jungnickel, Harald; Kock, Heiko; Tentschert, Jutta; Tlili, Ahmed; Schäffer, Andreas; Sips, Adriënne J.A.M.; Yokel, Robert A.; Luch, Andreas
Zeitschriftenaufsatz
2017Biological effects of carbon black nanoparticles are changed by surface coating with polycyclic aromatic hydrocarbons
Lindner, Karina; Ströbele, Michael; Schlick, Sandra; Webering, Sina; Jenckel, André; Kopf, Johannes; Danov, Olga; Sewald, Katherina; Buj, Christian; Creutzenberg, Otto; Tillmann, Thomas; Pohlmann, Gerhard; Ernst, Heinrich; Ziemann, Christina; Hüttmann, Gereon; Heine, Holger; Bockhorn, Henning; Hansen, Tanja; König, Peter
Zeitschriftenaufsatz
2017Blood eosinophils predict therapeutic effects of a GATA3-specific DNAzyme in asthma patients
Krug, N.; Hohlfeld, J.M.; Buhl, R.; Renz, J.; Garn, H.; Renz, H.
Zeitschriftenaufsatz
2017Catch and release: Rare cell analysis from a functionalised medical wire
Chen, Shukun; El-Heliebi, Amin; Tauber, Gerlinde; Langsenlehner, Tanja; Pötscher, Michaela; Kashofer, Karl; Czyz, Zbigniew T.; Polzer, Bernhard; Riethdorf, Sabine; Kuske, Andra; Leitinger, Gerd; Pantel, Klaus; Kroneis, Thomas; Sedlmayr, Peter
Zeitschriftenaufsatz
2017Class I histone deacetylases regulate p53/NF-kappaB crosstalk in cancer cells
Schäfer, Claudia; Göder, Anja; Beyer, Mandy; Kiweler, Nicole; Mahendrarajah, Nisintha; Rauch, Anke; Nikolova, Teodora; Stojanovic, Natasa; Wieczorek, Martin; Reich, Thomas R.; Tomicic, Maja T.; Linnebacher, Michael; Sonnemann, Jürgen; Dietrich, Sascha; Sellmer, Andreas; Mahboobi, Siavosh; Heinzel, Thorsten; Schneider, Günter; Krämer, Oliver H.
Zeitschriftenaufsatz
2017Coagulation factor XII regulates inflammatory responses in human lungs
Hess, R.; Wujak, L.; Hesse, C.; Sewald, K.; Jonigk, D.; Warnecke, G.; Fieguth, H.-G.; Maat, S. de; Maas, C.; Bonella, F.; Preissner, K.T.; Weiss, B.; Schaefer, L.; Kuebler, W.M.; Markart, P.; Wygrecka, M.
Zeitschriftenaufsatz
2017Common marmosets (Callithrix jacchus) can exhibit features of asthma
Curths, C.
Dissertation
2017Comparison Of Bleomycin Models Of Pulmonary Fibrosis In Rats And Mice
Walter, D.; Schaudien, D.; Sewald, K.; Braun, A.; Hoymann, H.G.
Abstract
2017Curated human hyperbilirubinemia data and the respective OATP1B1 and 1B3 inhibition predictions
Kotsampasakou, Eleni; Escher, Sylvia E.; Ecker, Gerhard F.
Zeitschriftenaufsatz
2017Differential lower airway dendritic cell patterns may reveal distinct endotypes of RSV bronchiolitis
Kerrin, A.; Fitch, P.; Errington, C.; Kerr, D.; Waxman, L.; Riding, K.; McCormack, J.; Mehendele, F.; McSorley, H.; MacKenzie, K.; Wronski, S.; Braun, A.; Levin, R.; Theilen, U.; Schwarze, J.
Zeitschriftenaufsatz
2017Disseminated tumour cells with highly aberrant genomes are linked to poor prognosis in operable oesophageal adenocarcinoma
Schumacher, S.; Bartenhagen, C.; Hoffmann, M.; Will, D.; Fischer, J.C.; Baldus, S.E.; Vay, C.; Fluegen, G.; Dizdar, L.; Vallböhmer, D.; Klein, C.A.; Knoefel, W.T.; Stoecklein, N.H.; Möhlendick, B.
Zeitschriftenaufsatz
2017Dose-response relationship of a new Timothy grass pollen allergoid in comparison with a 6-grass pollen allergoid
Pfaar, O.; Hohlfeld, J.M.; Al-Kadah, B.; Hauswald, B.; Homey, B.; Hunzelmann, N.; Schliemann, S.; Velling, P.; Worm, M.; Klimek, L.
Zeitschriftenaufsatz
2017Effect of a nano-silver coating on the quality of fresh turkey meat during storage after modified atmosphere or vacuum packaging
Deus, D.; Kehrenberg, C.; Schaudien, Dirk; Klein, G.; Krischek, Carsten
Zeitschriftenaufsatz
2017Effects from a 90-day inhalation toxicity study with cerium oxide and barium sulfate nanoparticles in rats
Schwotzer, D.; Ernst, H.; Schaudien, D.; Kock, H.; Pohlmann, G.; Dasenbrock, C.; Creutzenberg, O.
Zeitschriftenaufsatz
2017Erfahrungen und unterstützende Hinweise zur Anwendung von Nintedanib bei Patienten mit idiopathischer Lungenfibrose
Behr, Jürgen; Günther, Andreas; Kreuter, Michael; Koschel, Dirk; Prasse, Antje; Pfeifer, Michael; Costabel, Ulrich
Zeitschriftenaufsatz
2017Establishment of Neurospora crassa as a host for heterologous protein production using a human antibody fragment as a model product
Havlik, D.; Brandt, U.; Bohle, K.; Fleissner, A.
Zeitschriftenaufsatz
2017A European Respiratory Society technical standard: exhaled biomarkers in lung disease
Horvath, I.; Barnes, P.J.; Loukides, S.; Sterk, P.J.; Hogman, M.; Olin, A.C.; Amann, A.; Antus, B.; Baraldi, E.; Bikov, A.; Boots, A.W.; Bos, L.D.; Brinkman, P.; Bucca, C.; Carpagnano, G.E.; Corradi, M.; Cristescu, S.; Jongste, J.C. de; Dinh-Xuan, A.T.; Dompeling, E.; Fens, N.; Fowler, S.; Hohlfeld, J.M.; Holz, O.; Jobsis, Q.; Kant, K.V. van de; Knobel, H.H.; Kostikas, K.; Lehtimaki, L.; Lundberg, J.; Montuschi, P.; Muylem, A. van; Pennazza, G.; Reinhold, P.; Ricciardolo, F.L.M.; Rosias, P.; Santonico, M.; Schee, M.P. van der; Schooten, F.J. van; Spanevello, A.; Tonia, T.; Vink, T.J.
Zeitschriftenaufsatz
2017Evaluation of a human in vitro hepatocyte-NPC co-culture model for the prediction of idiosyncratic drug-induced liver injury: A pilot study
Granitzny, Anne; Knebel, Jan; Müller, Meike; Braun, Armin; Steinberg, Pablo; Dasenbrock, Clemens; Hansen, Tanja
Zeitschriftenaufsatz
2017Evaluation of inflammatory and immune responses in long-term cultured human precision-cut lung slices
Temann, A.; Golovina, T.; Neuhaus, V.; Thompson, C.; Chichester, J.A.; Braun, A.; Yusibov, V.
Zeitschriftenaufsatz, Konferenzbeitrag
2017Evaluation of Tier One Exposure Assessment Models (ETEAM): Project Overview and Methods
Tischer, M.; Lamb, J.; Hesse, S.; Tongeren, M. van
Zeitschriftenaufsatz
2017Ex-Vivo Infection Of Fresh Human Lung Tissue With Pseudomonas AerugINOSa
Boge, L.; Muller, M.; Jonigk, D.; Braubach, P.; Fieguth, H.G.; Warnecke, G.; Kruger, M.; Braun, A.; Sewald, K.; Wronski, S.
Abstract
2017Fraunhofer-Institut für Toxikologie und Experimentelle Medizin. Leistungen und Ergebnisse. Jahresbericht 2016/2017
: Nastevska, Cathrin (Red.); Schlemminger, Karin (Übers.)
Jahresbericht
2017FXII promotes proteolytic processing of the LRP1 ectodomain
Wujak, L.; Hesse, C.; Sewald, K.; Jonigk, D.; Braubach, P.; Warnecke, G.; Fieguth, H.-G.; Braun, A.; Lochnit, G.; Markart, P.; Schaefer, L.; Wygrecka, M.
Zeitschriftenaufsatz
2017GC-MS and GC-MS/MS measurement of ibuprofen in 10-μL aliquots of human plasma and mice serum using alpha-methylo-H-2(3)]ibuprofen after ethyl acetate extraction and pentafluorobenzyl bromide derivatization
Tsikas, Dimitrios; Kayacelebi, Arslan Arinc; Hanff, Erik; Mitschke, Anja; Beckmann, Bibiana; Tillmann, Hanns-Christian; Gutzki, Frank-Mathias; Müller, Meike; Bernasconi, Corrado
Zeitschriftenaufsatz
2017Health related quality of life in patients with idiopathic pulmonary fibrosis in clinical practice: insights-IPF registry
Kreuter, M.; Swigris, J.; Pittrow, D.; Geier, S.; Klotsche, J.; Prasse, A.; Wirtz, H.; Koschel, D.; Andreas, S.; Claussen, M.; Grohe, C.; Wilkens, H.; Hagmeyer, L.; Skowasch, D.; Meyer, J.F.; Kirschner, J.; Glaser, S.; Herth, F.J.F.; Welte, T.; Neurohr, C.; Schwaiblmair, M.; Held, M.; Bahmer, T.; Frankenberger, M.; Behr, J.
Zeitschriftenaufsatz
2017HER2 FISH results in breast cancers with increased CEN17 signals using alternative chromosome 17 probes - reclassifying cases in the equivocal category
Holzschuh, M.-A.; Czyz, Z.; Hauke, S.; Inwald, E.C.; Polzer, B.; Brockhoff, G.
Zeitschriftenaufsatz
2017High pressure processing assisted enzymatic hydrolysis - An innovative approach for the reduction of soy immunoreactivity
Meinlschmidt, Pia; Brode, Viktoria; Sevenich, R.; Ueberham, E.; Schweiggert-Weisz, U.; Lehmann, J.; Rauh, C.; Knorr, D.; Eisner, P.
Zeitschriftenaufsatz
2017A high-throughput method for the quantitative determination of free amino acids in saccharomyces cerevisiae by hydrophilic interaction chromatography-tandem mass spectrometry
Mülleder, M.; Bluemlein, K.; Ralser, M.
Zeitschriftenaufsatz
2017Human effector memory T helper cells engage with mouse macrophages and cause Graft-versus-Host-like pathology in skin of humanized mice used in a nonclinical immunization study
Sundarasetty, Balasai; Volk, Valery; Theobald, Sebastian J.; Rittinghausen, Susanne; Schaudien, Dirk; Neuhaus, Vanessa; Figueiredo, Constanca; Schneider, Andreas; Gerasch, Laura; Mucci, Adele; Moritz, Thomas; Kaisenberg, Constantin von; Spineli, Loukia M.; Sewald, Katherina; Braun, Armin; Weigt, Henning; Ganser, Arnold; Stripecke, Renata
Zeitschriftenaufsatz
2017In silico toxicology: An overview of toxicity databases, prediction methodologies, and expert review
Bower, D.; Cross, K.P.; Escher, Sylvia E.; Myatt, Glenn J.; Quigley, D.P.
Aufsatz in Buch
2017In vitro/ex vivo liver models for the prediction of idiosyncratic drug-induced liver injury
Granitzny, A.
Dissertation
2017Influence of lung CT changes in chronic obstructive pulmonary disease (COPD) on the human lung microbiome
Engel, M.; Endesfelder, D.; Schloter-Hai, B.; Kublik, S.; Granitsiotis, M.S.; Boschetto, P.; Stendardo, M.; Barta, I.; Dome, B.; Deleuze, J.F.; Boland, A.; Müller-Quernheim, J.; Prasse, A.; Welte, T.; Hohlfeld, J.; Subramanian, D.; Parr, D.; Gut, I.G.; Greulich, T.; Koczulla, A.R.; Nowinski, A.; Gorecka, D.; Singh, D.; Gupta, S.; Brightling, CE.; Hoffmann, H.; Frankenberger, M.; Hofer, TP.; Burggraf, D.; Heiss-Neumann, M.; Ziegler-Heitbrock, L.; Schloter, M.; Castell, W. zu
Zeitschriftenaufsatz
2017Influence of modified atmosphere and vacuum packaging with and without nanosilver-coated films on different quality parameters of pork
Kernberger-Fischer, I.; Kehrenberg, C.; Klein, G.; Schaudien, D.; Krischek, C.
Zeitschriftenaufsatz
2017Influences of Experimental Air Pollution on Human Sympathetic Nerve Traffic and Norepinephrine Metabolism: A Double Blind, Randomized, Twofold Crossover Study
Tank, J.; Heusser, K.; Holz, O.; May, M.; Brinkmann, J.; Diedrich, A.; Framke, T.; Koch, A.; Grosshennig, A.; Sweep, F.C.G.J.; Koch, W.; Krug, N.; Jordan, J.; Hohlfeld, J.
Abstract
2017Interactions Of Cancer Cell Line Mda-Mb-231 With Their Native Tumor Microenvironment And Anti-Cancer Effects Of Bevacizumab And Cisplatin On Cancer Cell Invaded Human Living Lung Tissue
Konzok, S.; Dehmel, S.; Braubach, P.; Kruger, M.; Jonigk, D.; Warnecke, G.; Pfennig, O.; Fieguth, H.G.; Braun, A.; Sewald, K.
Abstract
2017Intubation-free in vivo imaging of the tracheal mucosa using two-photon microscopy
Veres, Tibor Z.; Kopcsányi, Támas; Tirri, Marko; Braun, Armin; Miyasaka, Masayuki; Germain, Ronald N.; Jalkanen, Sirpa; Salmi, Marko
Zeitschriftenaufsatz
2017The isolated perfused lung (IPL) model for toxicity and efficacy testing and absorption studies of inhalable substances
Schwarz, K.; Fischer, M.; Dasenbrock, C.; Koch, W.; Walter, D.
Abstract
2017Legacy data sharing to improve drug safety assessment
Sanz, F.; Pognan, F.; Steger-Hartmann, T.; Díaz, C.; Cases, M.; Pastor, M.; Marc, P.; Wichard, J.; Briggs, K.; Watson, D.K.; Kleinöder, T.; Yang, C.; Amberg, A.; Beaumont, M.; Brookes, A.J.; Brunak, S.; Cronin, M.T.D.; Ecker, G.F.; Escher, S.; Greene, N.; Guzmán, A.; Hersey, A.; Jacques, P.; Lammens, L.; Mestres, J.; Muster, W.; Northeved, H.; Pinches, M.; Saiz, J.; Sajot, N.; Valencia, A.; Lei,, J. van der; Vermeulen, N.P.E.; Vock, E.; Wolber, G.; Zamora, I.
Zeitschriftenaufsatz
2017Linking organic anion transporting polypeptide 1B1 and 1B3 (OATP1B1 and OATP1B3) interaction profiles to hepatotoxicity - The hyperbilirubinemia use case
Kotsampasakou, Eleni; Escher, Sylvia E.; Ecker, Gerhard F.
Zeitschriftenaufsatz
2017Maintenance of high quality rat precision cut liver slices during culture to study hepatotoxic responses: Acetaminophen as a model compound
Granitzny, Anne; Knebel, Jan; Schaudien, Dirk; Braun, Armin; Steinberg, Pablo; Dasenbrock, Clemens; Hansen, Tanja
Zeitschriftenaufsatz
2017Molecular mechanism of early metastatic breast cancer dissemination
Hosseini, H.
Dissertation
2017The NAD+ precursor nicotinic acid improves genomic integrity in human peripheral blood mononuclear cells after X-irradiation
Weidele, Kathrin; Beneke, Sascha; Bürkle, Alexander
Zeitschriftenaufsatz
2017Non-human primate orthologues of TMPRSS2 cleave and activate the influenza virus hemagglutinin
Zmora, Pawel; Molau-Blazejewska, Paulina; Bertram, Stephanie; Walendy-Gnirß, Kerstin; Nehlmeier, Inga; Hartleib, Anika; Moldenhauer, Anna-Sophie; Konzok, Sebastian; Dehmel, Susann; Sewald, Katherina; Brinkmann, Constantin; Curths, Christoph; Knauf, Sascha; Gruber, Jens; Mätz-Rensing, Kerstin; Dahlmann, Franziska; Braun, Armin; Pöhlmann, Stefan
Zeitschriftenaufsatz
2017Organosilane-based coating of quartz species from the traditional ceramics industry: Evidence of hazard reduction using in vitro and in vivo tests
Ziemann, Christina; Escrig, Alberto; Bonvicini, Giuliana; Ibañez, Maria Jesus; Monfort, Eliseo; Salomoni, Arturo; Creutzenberg, Otto H.
Zeitschriftenaufsatz
2017Partikel‐ und Fasertoxikologie
Halter, Roman; Mangelsdorf, Inge
Aufsatz in Buch
2017Plasminogen activator inhibitor-1 is elevated in patients with COPD independent of metabolic and cardiovascular function
Waschki, Benjamin; Watz, Henrik; Holz, Olaf; Magnussen, Helgo; Olejnicka, Beata; Welte, Tobias; Rabe, Klaus F.; Janciauskiene, Sabina
Zeitschriftenaufsatz
2017The potential acute and chronic toxicity of cyfluthrin on the soil model organism, Eisenia fetida
Li, L.; Yang, D.; Song, Y.; Shi, Y.; Huang, B.; Bitsch, A.; Yan, J.
Zeitschriftenaufsatz
2017Pre-triggered dry and liquid aerosol release inside the patient interface of preterm neonates
Wiegandt, F.C.; Koch, E.; Iwatschenko, P.; Dietzel, A.; Pohlmann, G.
Abstract
2017Pseudomonas aeruginosa induziert eine angeborene Immunantwort in frischem Lungengewebe ex vivo
Kraemer, Nadine
: Braun, Armin (1. Prüfer); Häußler, Susanne (2. Prüfer); Wronski, Sabine (Betr.); Müller, Laura (Betr.)
Master Thesis
2017Read-across of 90-day rat oral repeated-dose toxicity: A case study for selected β-olefinic alcohols
Przybylak, Katarzyna R.; Schultz, Terry W.; Richarz, Andrea-N.; Mellor, Claire L.; Escher, Sylvia E.; Cronin, M.T.D.
Zeitschriftenaufsatz
2017Read-across of 90-day rat oral repeated-dose toxicity: A case study for selected n-alkanols
Schultz, Terry W.; Przybylak, Katarzyna R.; Richarz, Andrea-Nicole; Mellor, Claire L.; Escher, Sylvia E.; Bradbury, Steven P.; Cronin, Mark T. D.
Zeitschriftenaufsatz
2017Reduced microRNA-503 expression augments lung fibroblast VEGF production in chronic obstructive pulmonary disease
Ikari, J.; Nelson, A.J.; Obaid, J.; Giron-Martinez, A.; Ikari, K.; Makino, F.; Iwasawa, S.; Gunji, Y.; Farid, M.; Wang, X.; Basma, H.; Demeo, D.; Feghali-Bostwick, C.; Holz, O.; Rabe, K.; Liu, X.; Rennard, S.I.
Zeitschriftenaufsatz
2017Reply to Comment on 'Canine scent detection for the diagnosis of lung cancer in a screening-like situation'
Hackner, K.; Errhalt, P.; Doll, T.
Zeitschriftenaufsatz
2017Respirationstrakt
Schulz, F.
Aufsatz in Buch
2017RFIM fragrance ingredient safety assessment, acetaldehyde ethyl phenylethyl acetal, CAS Registry Number 2556-10-7
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment 2-heptylcyclopentanone, CAS Registry Number 137-03-1
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment 4-(Isopropyl)cyclohexyl propionate, CAS Registry Number 63449-95-6
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, .α.-methylcyclohexylmethyl acetate, CAS Registry Number 13487-27-9
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, 1-cyclohexylethyl butyrate, CAS Registry Number 63449-88-7
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, Jochen; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A. D.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, 1-methyl-3-methoxy-4-isopropylbenzene, CAS Registry Number 1076-56-8
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM Fragrance Ingredient Safety Assessment, 2,2,4-trimethyl-4-phenyl-butane-nitrile CAS Registry Number 75490-39-0
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, 2,2,5-trimethyl-5-pentylcyclopentanone, CAS Registry Number 65443-14-3
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, 2-isopropyl-4-methylanisole, CAS Registry Number 31574-44-4
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, 2-methyl-4(2,2,3-trimethyl-3-cyclopentenyl)butanol, CAS Registry Number 72089-08-8
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, 2-pentylcyclopentan-1-one, CAS Registry Number 4819-67-4
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, 3,12-Tridecadienenitrile CAS Registry Number 134769-33-8
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, 3,6-nonadien-1-ol, CAS registry number 76649-25-7
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, 3,7-dimethyl-1-octanol, CAS Registry Number 106-21-8
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, 3,7-dimethyl-1-octanyl acetate, CAS Registry Number 20780-49-8
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, 3,7-dimethyl-2,6-nonadienenitrile, CAS Registry Number 61792-11-8
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, 3-hexen-1-ol (isomer unspecified), CAS Registry Number 544-12-7
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, 3-methyl-2-pentylcyclopentan-1-one, CAS Registry Number 13074-63-0
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, 3-methylbutyl 2-methylpropanoate, CAS Registry Number 2050-01-3
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, 3-methylbutyl valerate, CAS Registry Number 2050-09-1
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, 4-(3,4-methylenedioxyphenyl)-2-butanone, CAS Registry Number 55418-52-5
Api, A.M.; Belsito, D.; Bhatia, S.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; Kromidas, L.; La Cava, S.; Lalko, J.F.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Politano, V.T.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.; Wall, B.; Wilcox, D.K.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, 4-Carvomenthenol, CAS Registry Number 562-74-3
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, 4-isopropyl-2-methoxy-1-methylbenzene, CAS Registry Number 6379-73-3
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, 5-Acetyl-3-isopropyl-1,1,2,6-tetramethylindane, CAS Registry Number 68140-48-7
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT, 6-acetyl-1,1,2,4,4,7-hexamethyltetraline, CAS Registry Number 21145-77-7
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Dekant, W.; Fryer, A.D.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, α-methylbenzyl alcohol, CAS registry number 98-85-1
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, α-Propylphenethyl alcohol, CAS Registry Number 705-73-7
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, acetaldehyde, diphenethyl acetal, CAS Registry Number 122-71-4
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, acetic acid, C7-9-branched alkyl esters, C8-rich, CAS Registry Number 108419-32-5
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, acetic acid, C8-10-branched alkyl esters, C9-rich, CAS Registry Number 108419-33-6
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, Alcohols, C11-14-iso-, C13-rich, CAS Registry Number 68526-86-3
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, alcohols, C8-10-iso-, C9-rich, CAS Registry Number 68526-84-1
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, β-Guaiene, CAS Registry Number 88-84-6
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Dekant, W.; Fryer, A.D.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, β-methylphenethyl alcohol, CAS Registry Number 1123-85-9
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, benzenepropanenitrile, 4-ethyl-.α.,.α.-dimethyl, CAS Registry Number 134123-93-6
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, benzenepropanol, a,ß-dimethyl-, CAS Registry Number 56836-93-2
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, benzoic acid, 2-[(1-oxopropyl)amino]-, methyl ester, CAS Registry Number 25628-84-6
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, butyl anthranilate, CAS Registry Number 7756-96-9
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, cis-3-octen-1-ol, CAS Registry Number 20125-84-2
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, cis-6-nonen-1-ol, CAS Registry Number 35854-86-5
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, Citronellyl nitrile, CAS Registry Number 51566-62-2
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, cuminyl nitrile, CAS Registry Number 13816-33-6
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, cyclohexanecarboxylic acid, 1,4-dimethyl-, methyl ester, trans- CAS Registry Number 23250-42-2
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM Fragrance Ingredient Safety Assessment, d-Cyclocitronellene acetate, CAS Registry Number 25225-10-9
Api, A.M.; Belsito, D.; Bhatia, S.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Kromidas, L.; La Cava, S.; Lalko, J.; Lapczynski, A.; Liebler, D.C.; Miyachi, Y.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Politano, V.T.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.; Wall, B.; Wilcox, D.K.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, decanal dimethyl acetal, CAS Registry Number 7779-41-1
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, dihydro-α-terpineol, CAS Registry Number 498-81-7
Api, A.M.; Belsito, D.; Bhatia, S.; Botelho, D.; Browne, D.; Bruze, M.; Burton, A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; Kromidas, L.; La Cava, S.; Lalko, J.F.; Lapczynski, A.; Liebler, D.C.; Miyachi, Y.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Politano, V.T.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.; Wall, B.; Wilcox, D.K.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, dihydro-β-ionol, cas registry number 3293-47-8
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, elemol, CAS Registry Number 639-99-6
Api, A.M.; Belsito, D.; Bhatia, S.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; Kromidas, L.; La Cava, S.; Lalko, J.F.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Politano, V.T.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.; Wall, B.; Wilcox, D.K.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, Ethyl 2,3,6-trimethylcyclohexyl carbonate, CAS Registry Number 93981-50-1
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, ethyl 2-tert-butylcyclohexyl carbonate, CAS Registry Number 67801-64-3
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, ethylene dodecanedioate, CAS registry number 54982-83-1
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, α-Isobutylphenethyl alcohol, CAS Registry Number 7779-78-4
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, isoamyl acetate, CAS Registry Number 123-92-2
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, isoamyl alcohol CAS Registry Number 123-51-3
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, Isoamyl butyrate, CAS Registry Number 106-27-4
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, isoamyl formate, CAS Registry Number 110-45-2
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, isoamyl hexanoate, CAS Registry Number 2198-61-0
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, Isoamyl octanoate, CAS Registry Number 2035-99-6
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, isoamyl propionate, CAS Registry Number 105-68-0
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, isobutyl N-methylanthranilate, CAS Registry Number 65505-24-0
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, isodecyl alcohol, CAS registry number 25339-17-7
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, Isolongifolene ketone, CAS registry number 23787-90-8
Api, A.M.; Belsito, D.; Bhatia, S.; Botelho, D.; Brown, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Fryer, A.D.; Kromidas, L.; Lalko, J.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Politano, V.T.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Thakkar, Y.; Wahler, J.; Wall, B.; Wilcox, D.K.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, isononyl propionate, CAS Registry Number 65155-45-5
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, isotridecyl acetate, CAS registry number 69103-23-7
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, l-Cyclocitronellene formate, CAS Registry Number 25225-08-5
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, menthyl acetate (isomer unspecified), CAS Registry Number 16409-45-3
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, menthyl isovalerate CAS Registry Number 16409-46-4
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, methyl anthranilate, CAS Registry Number 134-20-3
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, Methyl hexyl oxo cyclopentanone carboxylate, CAS Registry Number 37172-53-5
Api, A.M.; Belsito, D.; Bhatia, S.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; Kromidas, L.; La Cava, S.; Lalko, J.F.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Politano, V.T.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.; Wall, B.; Wilcox, D.K.
Zeitschriftenaufsatz
2017RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT, Methyl jasmonate, CAS Registry Number 1211-29-6
Api, A.M.; Belsito, D.; Bhatia, S.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; Kromidas, L.; La Cava, S.; Lalko, J.F.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Politano, V.T.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.; Wall, B.; Wilcox, D.K.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, methyl N-acetylanthranilate, CAS Registry Number 2719-08-6
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, Methylcyclooctyl carbonate, CAS Registry Number 61699-38-5
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, oxacyclohexadecane-2,13-dione, CAS Registry Number 38223-29-9
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, p-(2,2-dimethoxyethyl)toluene, CAS Registry Number 42866-91-1
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, p-methoxybenzonitrile, CAS Registry Number 874-90-8
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, phenylacetaldehyde diethyl acetal, CAS Registry Number 6314-97-2
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, propyl phenethyl acetal, CAS Registry Number 7493-57-4
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, terpineol, CAS Registry Number 8000-41-7
Api, A.M.; Belsito, D.; Bhatia, S.; Botelho, D.; Browne, D.; Bruze, M.; Burton, A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; Kromidas, L.; La Cava, S.; Lalko, J.F.; Lapczynski, A.; Liebler, D.C.; Miyachi, Y.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Politano, V.T.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.; Wall, B.; Wilcox, D.K.
Zeitschriftenaufsatz
2017RIFM fragrance ingredient safety assessment, tetrahydro-4-methyl-2-(2-methylpropen-1-yl)pyran, CAS Registry Number 16409-43-1
Api, A.M.; Belsito, D.; Bhatia, S.; Botelho, D.; Browne, D.; Bruze, M.; Burton, A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; Kromidas, L.; Cava, S. la; Lalko, J.F.; Lapczynski, A.; Liebler, D.C.; Miyachi, Y.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Politano, V.T.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.; Wall, B.; Wilcox, D.K.
Zeitschriftenaufsatz
2017RNA isolation from precision-cut lung slices (PCLS) from different species
Niehof, Monika; Hildebrandt, Tobias; Danov, Olga; Arndt, Kirsten; Koschmann, Jeannette; Dahlmann, Franziska; Hansen, Tanja; Sewald, Katherina
Zeitschriftenaufsatz
2017S2k-Leitlinie Idiopathische Lungenfibrose - Update zur medikamentösen Therapie 2017
Behr, Jürgen; Günther, Andreas; Bonella, Francesco; Geißler, Klaus; Koschel, Dirk; Kreuter, Michael; Prasse, Antje; Schönfeld, Nicolas; Sitter, Helmut; Müller-Quernheim, Joachim; Costabel, Ulrich
Zeitschriftenaufsatz
2017Specificity and reproducibility of nasal biomarkers in patients with allergic rhinitis after allergen challenge chamber exposure
Badorrek, Philipp; Müller, Meike; Koch, Wolfgang; Hohlfeld, Jens M.; Krug, Norbert
Zeitschriftenaufsatz
2017Supraglottic Atomization of Surfactant in Spontaneously Breathing Lambs Receiving Continuous Positive Airway Pressure
Milesi, Ilaria; Tingay, David G.; Lavizzari, Anna; Bianco, Federico; Zannin, Emanuela; Tagliabue, Paolo; Mosca, Fabio; Ventura, Maria L.; Rajapaksa, Anushi; Perkins, Elizabeth J.; Black, Don; Castri, Marco di; Sourial, Magdi; Pohlmann, Gerhard; Dellaca, Raffaele L.
Zeitschriftenaufsatz
2017Surfactant replacement therapy reduces acute lung injury and collapse induration-related lung remodeling in the bleomycin model
Steffen, L.; Ruppert, C.; Hoymann, H.-G.; Funke, M.; Ebener, S.; Kloth, C.; Mühlfeld, C.; Ochs, M.; Knudsen, L.; Lopez-Rodriguez, E.
Zeitschriftenaufsatz
2017Thoracic and respirable aerosol fractions of spray products containing non-volatile compounds
Schwarz, K.; Koch, W.
Zeitschriftenaufsatz
2017Transcriptome profiles in sarcoidosis and their potential role in disease prediction
Schupp, J.C.; Vukmirovic, M.; Kaminski, N.; Prasse, A.
Zeitschriftenaufsatz
2017A Transcriptome-driven Analysis of Epithelial Brushings and Bronchial Biopsies to Define Asthma Phenotypes in U-BIOPRED
Kuo, C.H.S.; Pavlidis, S.; Loza, M.; Baribaud, F.; Rowe, A.; Pandis, I.; Hoda, U.; Rossios, C.; Souse, A.; Wilson, S.J.; Howarth, P.; Dahlen, B.; Dahlen, S.E.; Chanez, P.; Shaw, D.; Krug, Norbert; Sandström, T.; Meulder, B. de; Lefaudeux, D.; Fowler, S.; Fleming, L.; Corfield, J.; Auffray, C.; Sterk, P.J.; Djukanovic, R.; Guo, Y.K.; Adcock, I.M.; Chung, K.F.
Zeitschriftenaufsatz
2017Translation of angiotensin-converting enzyme 2 upon liver- and lung-targeted delivery of optimized chemically modified mRNA
Schrom, E.; Huber, M.; Aneja, M.; Dohmen, C.; Emrich, D.; Geiger, J.; Hasenpusch, G.; Herrmann-Janson, A.; Kretzschmann, V.; Mykhailyk, O.; Pasewald, T.; Oak, P.; Hilgendorff, A.; Wohlleber, D.; Hoymann, H.-G.; Schaudien, D.; Plank, C.; Rudolph, C.; Kubisch-Dohmen, R.
Zeitschriftenaufsatz
2017U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics
Lefaudeux, D.; De Meulder, B.; Loza, M.J.; Peffer, N.; Rowe, A.; Baribaud, F.; Bansal, A.T.; Lutter, R.; Sousa, A.R.; Corfield, J.; Pandis, I.; Bakke, P.S.; Caruso, M.; Chanez, P.; Dahlén, S.-E.; Fleming, L.J.; Fowler, S.J.; Horvath, I.; Krug, N.; Montuschi, P.; Sanak, M.; Sandstrom, T.; Shaw, D.E.; Singer, F.; Sterk, P.J.; Roberts, G.; Adcock, I.M.; Djukanovic, R.; Auffray, C.; Chung, K.F.
Zeitschriftenaufsatz
2017Validation of Lower Tier Exposure Tools Used for REACH
Tongeren, M. van; Lamb, J.; Cherrie, J.W.; MacCalman, L.; Basinas, I.; Hesse, S.
Zeitschriftenaufsatz
2016"Watching the Detectives" report of the general assembly of the EU project DETECTIVE Brussels, 24-25 November 2015
Fernando, Ruani N.; Chaudhari, Umesh; Escher, Sylvia E.; Hengstler, Jan G.; Hescheler, Jürgen; Jennings, Paul; Keun, Hector C.; Kleinjans, Jos C.S.; Kolde, Raivo; Kollipara, Laxmikanth; Kopp-Schneider, Annette; Limonciel, Alice; Nemade, Harshal; Nguemo, Filomain; Peterson, Hedi; Prieto, Pilar; Rodrigues, Robim M.; Sachinidis, Agapios; Schäfer, Christoph; Sickmann, Albert; Spitkovsky, Dimitry; Stöber, Regina M.; Breda, Simone G.J. van; Water, Bob van de; Vivier, Manon; Zahedi, Rene P.; Vinken, Mathieu; Rogiers, Vera
Zeitschriftenaufsatz
2016α1-Antitrypsin (a1at) serum levels as marker of systemic inflammation in non-A1at-deficient patients with COPD
Waschki, B.; Kirsten, A.-M.; Holz, O.; Meyer, T.; Lichtinghagen, R.; Rabe, K.F.; Magnussen, H.; Welte, T.; Watz, H.; Janciauskiene, S.
Abstract
2016Acute toxicity and environmental risks of five veterinary pharmaceuticals for aquatic macroinvertebrates
Bundschuh, Mirco; Hahn, Torsten; Ehrlich, Bert; Höltge, Sibylla; Kreuzig, Robert; Schulz, Ralf
Zeitschriftenaufsatz
2016Alveolar escape by bacillus anthracis spores does not require a carrier cell and is not altered by lethal toxin
Booth, J.L.; Duggan, E.S.; Patel, V.I.; Metcalf, J.; Langer, M.; Coggeshall, K.M.; Braun, A.
Abstract
2016Angiopoietin-like protein 4 and cardiovascular function in COPD
Waschki, Benjamin; Kirsten, Anne-Marie; Holz, Olaf; Meyer, T.; Lichtinghagen, R.; Rabe, K.F.; Magnussen, Helgo; Welte, T.; Watz, H.; Janciauskiene, S.
Zeitschriftenaufsatz
2016Assessment of in vitro COPD models for tobacco regulatory science: Workshop proceedings, conclusions and paths forward for in vitro model use
Behrsing, H.; Raabe, H.; Manuppello, J.; Bombick, B.; Curren, R.; Sullivan, K.; Sethi, S.; Phipps, R.; Tesfaigzi, Y.; Yan, S.; D'Ruiz, C.; Tarran, R.; Constant, S.; Phillips, G.; Gaca, M.; Hayden, P.; Cao, X.; Mathis, C.; Hoeng, J.; Braun, A.; Hill, E.
Zeitschriftenaufsatz
2016Bacillus anthracis spore movement and uptake by cells resident in the human lung are not affected by anthrax lethal toxin
Metcalf, J.P.; Booth, J.L.; Duggan, E.S.; Patel, V.I.; Langer, M.; Braun, A.; Coggeshall, K.M.
Abstract
2016Bacillus anthracis spore movement does not require a carrier cell and is not affected by lethal toxin in human lung models
Booth, J.L.; Duggan, E.S.; Patel, V.I.; Langer, M.; Wu, W.; Braun, A.; Coggeshall, K.M.; Metcalf, J.P.
Zeitschriftenaufsatz
2016BI 1002494, a novel potent and selective oral spleen tyrosine kinase inhibitor, displays differential potency in human basophils and B cells
Lamb, David J.; Wollin, Stefan Lutz; Schnapp, Andreas; Bischoff, Daniel; Erb, Klaus J.; Bouyssou, Thierry; Guilliard, Bernd; Strasser, Christine; Wex, Eva; Blum, Sylvia; Thaler, Eva; Nickel, Helga; Radmacher, Oliver; Haas, Hannah; Swantek, Jennifer L.; Souza, Don; Canfield, Melissa; White, Della; Panzenbeck, Mark; Kashem, Mohammed A.; Sanville-Ross, Mary; Kono, Takeshi; Sewald, Katherina; Braun, Armin; Obernolte, Helena; Danov, Olga; Schaenzle, Gerhard; Rast, Georg; Maier, Gerd-Michael; Hoffmann, Matthias
Zeitschriftenaufsatz
2016Bridging across OECD 308 and 309 data in search of a robust biotransformation indicator
Honti, Mark; Hahn, Stefan; Hennecke, Dieter; Junker, Thomas; Shrestha, Prasit; Fenner, Kathrin
Zeitschriftenaufsatz
2016Canine scent detection for the diagnosis of lung cancer in a screening-like situation
Hackner, K.; Errhalt, P.; Mueller, M.R.; Speiser, M.; Marzluf, B.A.; Schulheim, A.; Schenk, P.; Bilek, J.; Doll, T.
Zeitschriftenaufsatz
2016Changes introduced with the new OECD 443 method and implications on the toxicological interpretation
Buschmann, J.
Abstract
2016Characterization of highly concentrated organic aerosols by optical extinction in the mid infrared regime
Dunkhorst, Wilhelm; Lipowicz, Peter; Koch, Wolfgang
Zeitschriftenaufsatz
2016Characterization of rare, dormant, and therapy-resistant cells in acute lymphoblastic leukemia
Ebinger, S.; Özdemir, E.Z.; Ziegenhain, C.; Tiedt, S.; Castro Alves, C.; Grunert, M.; Dworzak, M.; Lutz, C.; Turati, V.A.; Enver, T.; Horny, H.-P.; Sotlar, K.; Parekh, S.; Spiekermann, K.; Hiddemann, W.; Schepers, A.; Polzer, B.; Kirsch, S.; Hoffmann, M.; Knapp, B.; Hasenauer, J.; Pfeifer, H.; Panzer-Grümayer, R.; Enard, W.; Gires, O.; Jeremias, I.
Zeitschriftenaufsatz
2016Cigarette smoke and cigarette smoke condensate induce early biomarkers of inflammation and cytotoxicity in precision-cut lung slices
Obernolte, H.; Ritter, D.; Knebel, J.W.; Braubach, P.; Jonigk, D.; Fieguth, H.-G.; Braun, A.; Sewald, K.
Abstract
2016Comparative dosimetry for children and rodents exposed to extremely low-frequency magnetic fields
Gong, Yijian; Capstick, Myles; Dasenbrock, Clemens; Fedrowitz, Maren; Cobaleda, Cesar; Sanchez-Garcia, Isidro; Kuster, Niels
Zeitschriftenaufsatz
2016Comparison Of COPD related breath VOCs assessed by a compact high-resolution closed-loop GC-IMS and by standard GC-MS
Holz, O.; Allers, M.; Gaida, A.; Schuchardt, S.; Hohlfeld, J.M.; Zimmermann, S.
Abstract
2016Compounds with As-S bonds: Analytical and biogeochemical reasons why these species have been elusive in biota and environment
Feldmann, Jörg; Raab, Andrea; Hansen, Helle R.; Blümlein, Katharina; Wallschläger, Dirk
Aufsatz in Buch
2016Desktop exposure system and dosimetry for small scale in vivo radiofrequency exposure experiments
Gong, Yijian; Capstick, Myles; Tillmann, Thomas; Dasenbrock, Clemens; Samaras, Theodoros; Kuster, Niels
Zeitschriftenaufsatz
2016Development of an in vitro testing platform for aerosols containing inhalable antiobiotically active compounds as a part of the EU-project "PNeumoNP"
Ritter, D.; Knebel, J.; Wronski, S.; Montes, A.; Niehof, M.
Abstract
2016The Diagnosis, Differential Diagnosis, and Treatment of Sarcoidosis
Prasse, A.
Zeitschriftenaufsatz
2016Different pathways of inflammasome activation in human precision-cut lung slices (PCLS)
Konzok, S.; Braubach, P.; Peter, D.; Jonigk, D.; Fieguth, H.-G.; Braun, A.; Sewald, K.
Abstract
2016Double-blind randomized multicenter clinical trial to evaluate the specific and non-specific effects of AIT with a grass and a birch pollen allergoid
Wagenmann, M.; Hohlfeld, J.; Tribanek, M.; Homolla, V.; Karjalainen, M.; Häfner, D.
Abstract
2016A dual center study to compare breath volatile organic compounds from smokers and non-smokers with and without COPD
Gaida, Arne; Holz, Olaf; Nell, Christoph; Schuchardt, Sven; Lavae-Mokhtari, Bianca; Kruse, Lena; Boas, Ursula; Langejuergen, Jens; Allers, Maria; Zimmermann, Stefan
Zeitschriftenaufsatz
2016Early dissemination seeds metastasis in breast cancer
Hosseini, Hedayatollah; Obradović, Milan M.S.; Hoffmann, Martin; Harper, Kathryn L.; Sosa, Maria Soledad; Werner-Klein, Melanie; Nanduri, Lahiri Kanth; Werno, Christian; Ehrl, Carolin; Maneck, Matthias; Patwary, Nina; Haunschild, Gundula; Gužvić, Miodrag; Reimelt, Christian; Grauvogl, Michael; Eichner, Norbert; Weber, Florian; Hartkopf, Andreas D.; Taran, Florin-Andrei; Brucker, Sara Y.; Fehm, Tanja; Rack, Brigitte; Buchholz, Stefan; Spang, Rainer; Meister, Gunter; Aguirre-Ghiso, Julio A.; Klein, Christoph A.
Zeitschriftenaufsatz
2016Efficacy assessment of a novel disruptive IgE inhibitor in non-human primate and human precision-cut lung slices
Wichmann, J.; Jimenez-Delgado, S.; Curths, C.; Schmitt, A.; Dunker, S.; Jonigk, D.; Braubach, P.; Kaup, F.-J.; Braun, A.; Eggel, A.; Dahlmann, F.; Sewald, K.; Knauf, S.
Abstract
2016Emphysema- and airway-dominant COPD phenotypes defined by standardised quantitative computed tomography
Subramanian, Deepak R.; Gupta, Sumit; Burggraf, Dorothe; Silberberg, Suzan J. vom; Heimbeck, Irene; Heiss-Neumann, Marion S.; Haeussinger, Karl; Newby, Chris; Hargadon, Beverley; Raj, Vimal; Singh, Dave; Kolsum, Umme; Hofer, Thomas P.; Al-Shair, Khaled; Luetzen, Niklas; Prasse, Antje; Müller-Quernheim, Joachim; Benea, Giorgio; Leprotti, Stefano; Boschetto, Piera; Gorecka, Dorota; Nowinski, Adam; Oniszh, Karina; Castell, Wolfgang zu; Hagen, Michael; Barta, Imre; Döme, Balazs; Strausz, Janos; Greulich, Timm; Vogelmeier, Claus; Koczulla, Andreas R.; Gut, Ivo; Hohlfeld, Jens; Welte, Tobias; Lavae-Mokhtari, Mahyar; Ziegler-Heitbrock, Loems; Brightling, Christopher; Parr, David G.
Zeitschriftenaufsatz
2016Endocrine active environmental chemicals in foods
Schäfers, C.; Licht, O.; Bitsch, A.
Zeitschriftenaufsatz
2016Endokrin wirksame Umweltchemikalien in Lebensmitteln
Schäfers, C.; Licht, O.; Bitsch, A.
Zeitschriftenaufsatz
2016Endokrin wirksame Umweltchemikalien in Lebensmitteln
Schäfers, C.; Licht, O.; Bitsch, A.
Zeitschriftenaufsatz
2016Endokrin wirksame Umweltchemikalien in Lebensmitteln
Schäfers, C.; Licht, O.; Bitsch, A.
Zeitschriftenaufsatz
2016Endokrin wirksame Umweltchemikalien in Lebensmitteln
Schäfers, C.; Licht, O.; Bitsch, A.
Zeitschriftenaufsatz
2016Enzyme assisted degradation of potential soy protein allergens with special emphasis on the technofunctionality and the avoidance of a bitter taste formation
Meinlschmidt, Pia; Schweiggert-Weisz, Ute; Brode, V.; Eisner, Peter
Zeitschriftenaufsatz
2016Epigenetic silencing of the lung tumor suppressor cell adhesion molecule 1
Borlak, J.; Buettner, S.M.R.
Abstract
2016Evaluation of acute-to-chronic ratios of fish and Daphnia to predict acceptable no-effect levels
May, M.; Drost, W.; Germer, S.; Juffernholz, T.; Hahn, S.
Zeitschriftenaufsatz
2016Evaluation of route-to-route extrapolation factors based on assessment of repeated dose toxicity studies compiled in the database RepDose®
Schröder, Katrin; Escher, Sylvia E.; Hoffmann-Dörr, Simone; Kühne, R.; Simetska, Nelly; Mangelsdorf, Inge
Zeitschriftenaufsatz
2016Evaluation of the integrated testing strategy for PNEC derivation under REACH
May, Martin; Drost, Wiebke; Germer, Sabine; Juffernholz, Tanja; Hahn, Stefan
Zeitschriftenaufsatz
2016Expositionsvorrichtung
Brodbeck, Carsten; Ritter, Detlef; Knebel, Jan; Wolf, Klaus
Patent
2016Extracellular-signal regulated kinase (Erk1/2), mitogen-activated protein kinase-activated protein kinase 2 (MK2) and tristetraprolin (TTP) comprehensively regulate injury-induced immediate early gene (IEG) response in in vitro liver organ culture
Tran, Doan Duy Hai; Koch, Alexandra; Saran, Shashank; Armbrecht, Marcel; Ewald, Florian; Koch, Martina; Wahlicht, Tom; Wirth, Dagmar; Braun, Armin; Nashan, Bjorn; Gaestel, Matthias; Tamura, Teruko
Zeitschriftenaufsatz
2016Extremely low-frequency magnetic fields and risk of childhood leukemia: A risk assessment by the ARIMMORA consortium
Schüz, Joachim; Dasenbrock, Clemens; Ravazzani, Paolo; Röösli, Martin; Schär, Primo; Bounds, Patricia L.; Erdmann, Friederike; Borkhardt, Arndt; Cobaleda, Cesar; Fedrowitz, Maren; Hamnerius, Yngve; Sanchez-Garcia, Isidro; Seger, Rony; Schmiegelow, Kjeld; Ziegelberger, Gunde; Capstick, Myles; Manser, Melissa; Müller, Meike; Schmid, Christoph D.; Schürmann, David; Struchen, Benjamin; Kuster, Niels
Zeitschriftenaufsatz
2016FR-900098, an antimalarial development candidate that inhibits the non-mevalonate isoprenoid biosynthesis pathway, shows no evidence of acute toxicity and genotoxicity
Wiesner, Jochen; Ziemann, Christina; Hintz, Martin; Reichenberg, Armin; Ortmann, Regina; Schlitzer, Martin; Fuhst, Rainer; Timmesfeld, Nina; Vilcinskas, Andreas; Jomaa, Hassan
Zeitschriftenaufsatz
2016Fraunhofer-Institut für Toxikologie und Experimentelle Medizin. Leistungen und Ergebnisse. Jahresbericht 2015
 
Jahresbericht
2016Functional, histological and biochemical endpoints for assessing antifibrotic efficacy in a rat model of pulmonary fibrosis
Hoymann, H.G.; Schaudien, D.; Hansen, T.; Niehof, M.; Braun, A.
Abstract
2016Histopathological findings after 12 months inhalation to nano Ceria
Ernst, Heinrich; Ma-Hock, Lan; Keller, J.; Groeters, Sibylle; Ravenzwaay, Bennard van; Gebel, Thomas; Schaudien, Dirk; Rittinghausen, Susanne; Landsiedel, Robert
Abstract
2016In vitro and in vivo investigations to obtain validated toxicity data of graphene nanoplatelets
Farcal, L.; Ziemann, C.; Oliveira, H.; Burla, S.; Creutzenberg, O.
Abstract
2016Indoor air guide values for glycol ethers and glycol esters - A category approach
Mangelsdorf, Inge; Nordqvist Kleppe, Sara; Heinzow, Birger; Sagunski, Helmut
Zeitschriftenaufsatz
2016Inhalation threshold of toxicological concern (TTC) - structural alerts discriminate high from low repeated-dose inhalation toxicity
Schüürmann, Gerrit; Ebert, Ralf-Uwe; Tluczkiewicz, Inga; Escher, S.E.; Kühne, R.
Zeitschriftenaufsatz
2016Inhalation TTC values: A new integrative grouping approach considering structural, toxicological and mechanistic features
Tluczkiewicz, Inga; Kühne, Ralph; Ebert, Ralf-Uwe; Batke, Monika; Schüürmann, Gerrit; Mangelsdorf, Inge; Escher, Sylvia E.
Zeitschriftenaufsatz
2016Innovative strategies to develop chemical categories using a combination of structural and toxicological properties
Batke, Monika; Gütlein, Martin; Partosch, Falko; Gundert-Remy, Ursula; Helma, Christoph; Kramer, Stefan; Maunz, Andreas; Seeland, Madeleine; Bitsch, Annette
Zeitschriftenaufsatz
2016Insights from the German Compassionate Use Program of Nintedanib for the Treatment of Idiopathic Pulmonary Fibrosis
Bonella, Francesco; Kreuter, Michael; Hagmeyer, Lars; Neurohr, Claus; Keller, Claus; Kohlhaeufl, Martin J.; Müller-Quernheim, Joachim; Milger, Katrin; Prasse, Antje; Behr, J.; Hetzel, J.; Idzko, M.; Kardos, P.; Koch, A.; Markart, P.; Reichenberger, F.; Schumann, C.; Westhoff, M.; Windisch, W.
Zeitschriftenaufsatz
2016Interleukin-2 receptor and angiotensin-converting enzyme as markers for ocular sarcoidosis
Gundlach, Enken; Hoffmann, Michael Marcus; Prasse, Antje; Heinzelmann, Sonja; Ness, Thomas
Zeitschriftenaufsatz
2016Longitudinal replication of severe asthma exhaled breath phenotypes by the U-BIOPRED electronic nose platform
Brinkman, P.; Wagener, A.H.; Hekking, P.-P.; Bansal, A.T.; Wang, Y.; Weda, H.; Knobel, H.H.; Vink, T.J.; Rattray, N.J.; D'Amico, A.; Pennazza, G.; Santonico, M.; Bakke, P.S.; Caruso, M.; Chung, K.F.; Corfield, J.; Dahlen, S.E.; Djukanovic, R.; Geiser, T.; Horvath, I.; Krug, N.; Musial, J.; Shaw, D.E.; Pandis, I.; Sandstrom, T.; Sousa, A.R.; Montuschi, P.; Fowler, S.J.; Sterk, P.J.
Abstract
2016Marmoset monkeys as a model for human allergic asthma
Curths, C.; Jimenez-Delgado, S.; Wichmann, J.; Kap, Y.; Kaup, F.-J.; Braun, A.; Sewald, K.; Knauf, S.; Dahlmann, F.
Abstract
2016Massive clonal selection and transiently contributing clones during expansion of mesenchymal stem cell cultures revealed by lentiviral RGB-barcode technology
Selich, Anton; Daudert, Jannik; Hass, Ralf; Philipp, Friederike; Kaisenberg, Constantin von; Paul, Gabi; Cornils, Kerstin; Fehse, Boris; Rittinghausen, Susanne; Schambach, Axel; Rothe, Michael
Zeitschriftenaufsatz
2016Mathematical modeling of di-ethyl-hexyl-sebacate nanoparticle formation in a free turbulent jet under high nucleation rate conditions
Gilfanov, Artur K.; Koch, Wolfgang; Zaripov, Shamil K.
Zeitschriftenaufsatz
2016Measurement of exhaled volatile organic compounds from patients with chronic obstructive pulmonary disease (COPD) using closed gas loop GC-IMS and GC-APCI-MS
Allers, Maria; Langejuergen, Jens; Gaida, Arne; Holz, Olaf; Schuchardt, Sven; Hohlfeld, Jens M.; Zimmermann, Stefan
Zeitschriftenaufsatz
2016Mechanism of early dissemination and metastasis in Her2+ mammary cancer
Harper, Kathryn L.; Sosa, Maria Soledad; Entenberg, David; Hosseini, Hedayatollah; Cheung, Julie F.; Nobre, Rita; Avivar-Valderas, Alvaro; Nagi, Chandandaneep; Girnius, Nomeda; Davis, Roger J.; Farias, Eduardo F.; Condeelis, John; Klein, Christoph A.; Aguirre-Ghiso, Julio A.
Zeitschriftenaufsatz
2016Mechanisms underlying epigenetic and transcriptional heterogeneity in Chinese hamster ovary (CHO) cell lines
Veith, Nathalie; Ziehr, Holger; MacLeod, Roderick A.F.; Reamon-Büttner, Stella Marie
Zeitschriftenaufsatz
2016Method for identification of low soluble, biopersistent dusts (GBS)
Creutzenberg, O.; Hansen, T.; Sven, S.; Thomas, T.; Jan, K.
Abstract
2016Method for identification of low soluble, biopersistent susts (GBS) - comparison of intratracheal installation and subacute inhalation
Creutzenberg, Otto H.; Hansen, Tanja; Schuchardt, Sven; Tillmann, Thomas; Knebel, Jan
Abstract
2016Mice produced by mitotic reprogramming of sperm injected into haploid parthenogenotes
Suzuki, Toru; Asami, Maki; Hoffmann, Martin; Lu, Xin; Guzvic, Miodrag; Klein, Christoph A.; Perry, Anthony C.F.
Zeitschriftenaufsatz
2016Morphology and staining behavior of neutrophilic and eosinophilic granulocytes of the common marmoset (Callithrix jacchus)
Bleyer, Martina; Curths, Christoph; Dahlmann, Franziska; Wichmann, Judy; Bauer, Natali; Moritz, Andreas; Braun, Armin; Knauf, Sascha; Kaup, Franz-Josef; Gruber-Dujardin, Eva
Zeitschriftenaufsatz
2016No GVHD, but Human Inflammatory "Cytokine Storm" and Mouse Macrophage Activation Upon Accelerated Development of Human CD4+ Effector Memory T Cells in Long-Term Humanized Mice
Sundarasetty, B.S.; Schneider, A.; Sewald, K.; Rittinghausen, S.; Braun, A.; Figueiredo, C.; Ganser, A.; Stripecke, R.
Abstract
2016Nonproliferative and proliferative lesions of the rat and mouse skeletal tissues (bones, joints, and teeth)
Fossey, Stacey; Vahle, John; Long, Philip; Schelling, Scott; Ernst, Heinrich; Boyce, Rogely Waite; Jolette, Jacquelin; Bolon, Brad; Bendele, Alison; Rinke, Matthias; Healy, Laura; High, Wanda; Roth, Daniel Robert; Boyle, Michael; Leininger, Joel
Zeitschriftenaufsatz
2016A novel disruptive IgE inhibitor: Efficacy assessment in non-human primate and human precision-cut lung slices
Wichmann, J.; Jimenez-Delgado, S.; Curths, C.; Schmitt, A.; Dunker, S.; Jonigk, D.; Braubach, P.; Kaup, F.J.; Braun, A.; Dahlmann, F.; Eggel, A.; Sewald, K.; Knauf, S.
Abstract
2016Numerical study of nanoparticle formation in a free turbulent jet
Gilfanov, A.K.; Koch, W.; Zaripov, S.K.; Rybdylova, O.D.
Konferenzbeitrag
2016Prevalence of ragweed sensitization at a clinical trial unit in northern Germany
Badorrek, P.; Krug, N.; Hohlfeld, J.M.
Abstract
2016Prevalidation of the ex-vivo model PCLS for prediction of respiratory toxicity
Hess, A.; Wang-Lauenstein, Lan; Braun, Armin; Kolle, S.N.; Landsiedel, Robert; Liebsch, M.; Ma-Hock, Lan; Pirow, R.; Schneider, X.; Steinfath, M.; Vogel, S.; Martin, C.; Sewald, Katherina
Zeitschriftenaufsatz
2016Rating the value of COPD related breath VOCs in models created by linear discriminant analysis
Holz, O.; Gaida, A.; Nell, C.; Allers, M.; Schuchardt, S.; Zimmermann, S.; Koczulla, R.; Hohlfeld, J.M.
Abstract
2016Recommendations from the INHAND Apoptosis/Necrosis Working Group
Elmore, Susan A.; Dixon, Darlene; Hailey, James R.; Harada, Takanori; Herbert, Ronald A.; Maronpot, Robert R.; Nolte, Thomas; Rehg, Jerold E.; Rittinghausen, Susanne; Rosol, Thomas J.; Satoh, Hiroshi; Vidal, Justin D.; Willard-Mack, Cynthia L.; Creasy, Dianne M.
Zeitschriftenaufsatz
2016RIFM fragrance ingredient safety assessment, 2-Hydroxy-α,α,4-trimethylcyclohexanemethanol, CAS Registry Number 42822-86-6
Api, A.M.; Belsito, D.; Bhatia, S.; Bruze, M.; Burton, G.A.; Buschmann, Jochen; Calow, P.; Dagli, M.L.; Dekant, W.; Fryer, A.D.; Kromidas, L.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Penning, T.M.; Politano, V.T.; Ritacco, G.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Wall, B.; Wilcox, D.K.
Zeitschriftenaufsatz
2016Safety, efficacy and repeatability of a novel house dust mite allergen challenge technique in the Fraunhofer allergen challenge chamber
Lüer, Katrin; Biller, Heike; Casper, Anja; Windt, Horst; Müller, Meike; Badorrek, Philipp; Haefner, Dietrich; Framke, Theodor; Koch, A.; Ziehr, Holger; Krug, Norbert; Koch, Wolfgang; Hohlfeld, Jens M.
Zeitschriftenaufsatz
2016Screening for potential endocrine disruptors in fish: Evidence from structural alerts and in vitro and in vivo toxicological assays
Nendza, Monika; Wenzel, Andrea; Müller, Martin; Lewin, Geertje; Simetska, Nelly; Stock, Frauke; Arning, Jürgen
Zeitschriftenaufsatz
2016Severe asthma exists despite suppressed tissue inflammation: Findings of the U-BIOPRED study
Wilson, Susan J.; Ward, Jonathan A.; Sousa, Ana R.; Corfield, Julie; Bansal, Aruna T.; Meulder, Bertrand de; Lefaudeux, Diane; Auffray, Charles; Loza, Matthew J.; Baribaud, Frédéric; Fitch, Neil; Sterk, Peter J.; Chung, Kian Fan; Gibeon, David; Sun, Kai; Guo, Yi-Ke; Adcock, Ian M.; Djukanovic, Ratko; Dahlén, Barbro; Chanez, Pascal; Shaw, Dominick E.; Krug, Norbert; Hohlfeld, Jens; Sandström, Thomas; Howarth, Peter H.
Zeitschriftenaufsatz
2016Sicherheit, Wirksamkeit und Reproduzierbarkeit einer neuen Provokationstechnik mit Hausstaubmilben im Fraunhofer-Allergenprovokationsraum
Lüer, K.
Dissertation
2016Simulation studies to explore biodegradation in water-sediment systems: From OECD 308 to OECD 309
Shrestha, Prasit; Junker, Thomas; Fenner, Kathrin; Hahn, Stefan; Honti, Mark; Bakkour, Rani; Diaz, Cecilia; Hennecke, Dieter
Zeitschriftenaufsatz
2016Single-cell analysis of CTCs with diagnostic precision: Opportunities and challenges for personalized medicine. Review
Alberter, Barbara; Klein, Christoph A.; Polzer, Bernhard
Zeitschriftenaufsatz
2016Spontaneous malignant craniopharyngioma in an aged Wistar rat
Heinrichs, Martin; Ernst, Heinrich
Zeitschriftenaufsatz
2016Steroid treatment reduces allergic airway inflammation and does not alter the increased numbers of dendritic cells and calcitonin gene-related peptide-expressing neurons in airway sensory ganglia
Le, Duc Dung; Funck, Ulrike; Wronski, Sabine; Heck, Sebastian; Tschernig, Thomas; Bischoff, Markus; Sester, Martina; Herr, Christian; Bals, Robert; Welte, Tobias; Braun, Armin; Dinh, Quoc Thai
Zeitschriftenaufsatz
2016Thresholds of toxicological concern - overview of ongoing scientific developments
Escher, S.; Turek, C.; Campos, S.; Edwards, J.; Ferret, P.; Höfer, N.; Kosemund, K.; Schnabel, J.; Ravenzwaay, B. van; Hollnagel, H.M.
Abstract
2016Tierversuchsfreie Methoden in der Toxikologie
Koschmann, J.; Sewald, K.; Escher, S.E.
Zeitschriftenaufsatz
2016Tiotropium respimat® versus hHndiHaler®: Comparison of bronchodilator efficacy of various doses in clinical trials
Calverley, Peter M.A.; Könen-Bergmann, Michael; Richard, Frank; Bell, Susan; Hohlfeld, Jens M.
Zeitschriftenaufsatz
2016Towards prevention of metastatic prostate cancer
Gužvić, M.; Klein, C.A.
Zeitschriftenaufsatz
2016Toxicity of CeO2 nanoparticles estimated in a 90-day nose-only inhalation study
Schwotzer, Daniela; Niehof, Monika; Hansen, Tanja; Schuchardt, Sven; Tillmann, Thomas; Ernst, Heinrich; Creutzenberg, Otto H.
Abstract
2016Toxicity of cerium dioxide nanoparticles - effects from a 90-day inhalation study
Schwotzer, D.; Niehof, M.; Hansen, T.; Tillmann, T.; Ernst, H.; Creutzenberg, O.
Abstract
2016Transient Receptor Potential (TRP) ion channels activation in vital human precision-cut lung slices lead to bronchoconstriction and is neuropeptide substance P-dependent
Delgado, S.M.J.; Obernolte, H.; Hobbie, S.; Schindler, S.; Jonigk, D.; Warnecke, G.; Braubach, P.; Bersch, C.; Pfennig, O.; Fieguth, H.G.; Sewald, K.; Braun, A.
Abstract
2016Translocation and biokinetic behavior of nanoscaled europium oxide particles within 5 days following an acute inhalation in rats
Creutzenberg, Otto H.; Kock, Heiko; Schaudien, Dirk
Zeitschriftenaufsatz
2016Use of computational fluid dynamics for optimization of cell-based in vitro methods in inhalation research
Brodbeck, C.; Wolf, K.; Ritter, D.; Knebel, J.
Abstract
2016Validated and longitudinally stable asthma phenotypes based on cluster analysis of the ADEPT study
Loza, M.J.; Djukanovic, R.; Chung, K.F.; Horowitz, D.; Ma, K.; Branigan, P.; Barnathan, E.S.; Susulic, V.S.; Silkoff, P.E.; Sterk, P.J.; Baribaud, F.; Badorrek, P.; Faulenbach, C.; Braun, A.; Hohlfeld, J.; Krug, N.; et. al.
Zeitschriftenaufsatz
2016Viral infection of the central nervous system exacerbates interleukin-10 receptor deficiency-mediated colitis in SJL mice
Uhde, Ann-Kathrin; Herder, Vanessa; Akram Khan, Muhammad; Ciurkiewicz, Malgorzata; Schaudien, Dirk; Teich, Rene; Floess, Stefan; Baumgärtner, Wolfgang; Huehn, Jochen; Beineke, Andreas
Zeitschriftenaufsatz
2015 Untersuchungen zur Leistungsfähigkeit von Zelllinien mit Kassettenaustauschsystem
Bludau, E.
Dissertation
2015Acute inhalation toxicity of volatile organic compounds - application of an improved cell-based in vitro procedure
Ritter, Detlef; Krakor, E.; Knebel, Jan
Abstract
2015Acute toxicity testing of inhalable/gaseous compounds by cell-based methods in vitro - application to volatile organic compounds
Ritter, Detlef; Knebel, Jan
Abstract
2015Allergen-induced asthmatic responses modified by a GATA3-specific DNAzyme
Krug, Norbert; Hohlfeld, Jens Michael; Kirsten, Anne-Marie; Kornmann, Oliver; Beeh, Kai-Michael; Kappeler, Dominik; Korn, Stephanie; Ignatenko, Stanislav; Timmer, Wolfgang; Rogon, Cordelia; Zeitvogel, Jana; Zhang, Nan; Bille, Joachim; Homburg, Ursula; Turowska, Agnieszka; Bachert, Claus; Werfel, Thomas; Buhl, Roland; Renz, Jonas; Garn, Holger; Renz, Harald
Zeitschriftenaufsatz
2015Assessing the breathing capability of patients through inhalers
Pohlmann, G.; Hohlfeld, J.; Pankalla, J.
Konferenzbeitrag, Zeitschriftenaufsatz
2015Assessment of mechanisms driving non-linear dose-response relationships in genotoxicity testing
Guerard, M.; Baum, M.; Bitsch, Annette; Eisenbrand, G.; Elhajouji, A.; Epe, B.; Habermeyer, M.; Kaina, B.; Martus, H.J.; Pfuhler, S.; Schmitz, C.; Sutter, A.; Thomas, A.D.; Ziemann, Christina; Froetschl, R.
Zeitschriftenaufsatz
2015Beryllium concentrations at european workplaces: Comparison of 'total' and inhalable particulate measurements
Kock, Heiko; Civic, Terence; Koch, Wolfgang
Zeitschriftenaufsatz
2015Beryllium concentrations at European workplaces: Comparison of ‘total’ and inhalable particulate measurements
Koch, W.; Kock, H.; Civic, T.
Konferenzbeitrag, Zeitschriftenaufsatz
2015Biologische Wirkungen synthetisch hergestellter Multiwall-Carbon-Nanotubes am Tiermodell und in der Zellkultur
Hackbarth, Anja
: Steinberg, Pablo (Wiss. Betreuer); Dasenbrock, Clemens (Wiss. Betreuer); Steinberg, Pablo (1. Gutachter); Kietzmann, Manfred (2. Gutachter)
Dissertation
2015Cardiac safety of tiotropium in patients with COPD: A combined analysis of Holter-ECG data from four randomised clinical trials
Hohlfeld, Jens Michael; Furtwaengler, A.; Könen-Bergmann, M.; Wallenstein, G.; Walter, B.; Bateman, E.D.
Zeitschriftenaufsatz
2015Cellular uptake of different nano and bulk metal oxide particles by cells derived from epidermal, intestinal and leukocyte cell lines
Requardt, H.; Hansen, T.; Eisenbarth, E.; Hampel, S.; Dasenbrock, C.
Konferenzbeitrag, Zeitschriftenaufsatz
2015Characterization of exhaled particles from the human lungs in airway obstruction
Schwarz, Katharina; Biller, Heike; Windt, Horst; Koch, Wolfgang; Hohlfeld, Jens M.
Zeitschriftenaufsatz
2015The ChemScreen project to design a pragmatic alternative approach to predict reproductive toxicity of chemicals
Burg, Bart van der; Bay Wedebye, Eva; Dietrich, Daniel R.; Jaworska, Joanna; Mangelsdorf, Inge; Paune, Eduard; Schwarz, Michael; Piersma, Aldert H.
Zeitschriftenaufsatz
2015Childhood asthma is associated with mutations and gene expression differences of ORMDL genes that can interact
Toncheva, A.A.; Potaczek, D.P.; Schedel, M.; Gersting, S.W.; Michel, S.; Krajnov, N.; Gaertner, V.D.; Klingbeil, J.M.; Illig, T.; Franke, A.; Winkler, Carla; Hohlfeld, Jens M.; Vogelberg, C.; Berg, A. von; Bufe, A.; Heinzmann, A.; Laub, O.; Rietschel, E.; Simma, B.; Genuneit, J.; Muntau, A.C.; Kabesch, Michael
Zeitschriftenaufsatz
2015Cholinergic urethral brush cells are widespread throughout placental mammals
Deckmann, Klaus; Krasteva-Christ, Gabriela; Rafiq, Amir; Herden, Christine; Wichmann, Judy; Knauf, Sascha; Nassenstein, Christina; Grevelding, Christoph G.; Dorresteijn, Adriaan; Chubanov, Vladimir; Gudermann, Thomas; Bschleipfer, Thomas; Kummer, Wolfgang
Zeitschriftenaufsatz, Konferenzbeitrag
2015Cigarette smoke and cigarette smoke condensate exposure induces cytotoxicity and inflammation in precision-cut lung slices
Obernolte, Helena; Konzok, Sebastian; Ritter, Detlef; Knebel, Jan; Braubach, Peter; Jonigk, Danny; Fieguth, Hans-Gerd; Braun, Armin; Sewald, Katherina
Abstract
2015Cigarette smoke and cigarette smoke condensate induce cell injury and early biomarkers of inflammation in human and rodent Precision-Cut Lung Slices
Obernolte, Helena; Ritter, Detlef; Knebel, Jan W.; Braubach, Peter; Jonigk, Danny; Braun, Armin; Sewald, Katherina
Abstract
2015Cigarette smoke condensate and cigarette smoke induce cytotoxicity and inflammation in human and rodent Precision-Cut Lung Slices of different species
Obernolte, Helena; Konzok, Sebastian; Ritter, Detlef; Knebel, Jan W.; Braubach, Peter; Jonigk, Danny; Braun, Armin; Sewald, Katherina
Abstract
2015Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort
Shaw, Dominick E.; Sousa, Ana R.; Fowler, Stephen J.; Fleming, Louise J.; Roberts, Graham; Corfield, Julie; Pandis, Ioannis; Bansal, Aruna T.; Bel, Elisabeth H.; Auffray, Charles; Compton, Chris H.; Bisgaard, Hans; Bucchioni, Enrica; Caruso, Massimo; Chanez, Pascal; Dahlén, Barbro; Dahlén, Sven-Erik; Dyson, Kerry; Frey, Urs; Geiser, Thomas; Gerhardsson de Verdier, Maria; Gibeon, David; Guo, Yi-Ke; Hashimoto, Simone; Hedlin, Gunilla; Jeyasingham, Elizabeth; Hekking, Pieter-Paul W.; Higenbottam, Tim; Horváth, Ildikó; Knox, Alan J.; Krug, Norbert; Erpenbeck, Veit J.; Larsson, Lars X.; Lazarinis, Nikos; Matthews, John G.; Middelveld, Roelinde; Montuschi, Paolo; Musial, Jacek; Myles, David; Pahus, Laurie; Sandström, Thomas; Seibold, Wolfgang; Singer, Florian; Strandberg, Karin; Vestbo, Jorgen; Vissing, Nadja; Garnier, Christophe von; Adcock, Ian M.; Wagers, Scott; Rowe, Anthony; Howarth, Peter; Wagener, Ariane H.; Djukanovic, Ratko; Sterk, Peter J.; Chung, Kian Fan
Zeitschriftenaufsatz
2015Comparative data-mining across multiple toxicity databases harmonized by eTOX ontology to test hypotheses
Steger-Hartmann, T.; Pognan, F.; Sanz, F.; Briggs, K.; Escher, Sylvia; Kleinoeder, T.; Schwab, C.; Wichard, J.; Yang, C.
Abstract
2015Comparison of fibrotic and emphysematous alterations in the lungs of bleomycin-treated rats and hamsters
Hoymann, Heinz-G.; Schaudien, Dirk; Hansen, Tanja; Müller, Meike; Braun, Armin
Abstract
2015Comparison of two different application routes of nanosilver in rats - evidence for nanoparticles after silver ion treatment
Juling, S.; Lichtenstein, D.; Selve, S.; Oberemm, A.; Creutzenberg, Otto; Braeuning, A.; Lampen, A.
Abstract
2015Constant-load exercise decreases the serum concentration of myeloperoxidase in healthy smokers and smokers with COPD
Holz, Olaf; Roepcke, Stefan; Watz, Henrik; Tegtbur, Uwe; Lahu, Gezim; Hohlfeld, Jens Michael
Zeitschriftenaufsatz
2015Constructing an adverse outcome pathway for sensitization of the respiratory tract: Network thinking meets regulatory utility
Sullivan, K.; Cochrane, S.; Enoch, S.J.; Ezendam, J.; Patlewicz, G.; Roggen, E.L.; Sewald, Katherina
Abstract
2015Continuing harmonization of terminology and innovations for methodologies in developmental toxicology
Solecki, Roland; Rauch, Martina; Gall, Andrea; Buschmann, Jochen; Clark, Ruth; Fuchs, Antje; Kan, Haidong; Heinrich, Verena; Kellner, Rupert; Knudsen, Thomas B.; Li, Weihua; Makris, Susan L.; Ooshima, Yojiro; Paumgartten, Francisco; Piersma, Aldert H.; Schönfelder, Gilbert; Oelgeschläger, Michael; Schaefer, Christof; Shiota, Kohei; Ulbrich, Beate; Ding, Xuncheng; Chahoud, Ibrahim
Zeitschriftenaufsatz
2015Controlled exposure to grass pollen in an environmental challenge chamber induces a worsening of cutaneous symptoms in patients with atopic dermatitis
Heratizadeh, A.; Badorrek, P.; Kapp, A.; Niebuhr, M.; Roesner, L.M.; Karch, A.; Erpenbeck, V.J.; Loesche, C.; Jung, T.; Krug, N.; Hohlfeld, J.M.; Werfel, T.
Abstract
2015DETECTIVE: Detection of Endpoints and Biomarkers for Repeated Dose Toxicity using in vitro Systems
Wink, S.; Water, B. van de; Reif, R.; Hammad, S.; Stöber, R.; Widera, A.; Hengstler, J.; Limonciel, A.; Jennings, P.; Escher, S.; Keun, H.; Kleinjans, J.; Kopp-Schneider, A.; Peterson, H.; Ringwald, A.; Rogiers, V.; Sachinidis, A.; Sickmann, A.; Vinken, M.; Spitkovsky, D.; Hescheler, J.
Aufsatz in Buch
2015Determination of markers that predict the individual response of perennial allergic subjects to house dust mite allergen in the Fraunhofer Environmental Challenge Chamber (ECC)
Hohlfeld, J.M.; Lüer, K.; Holz, O.; Häfner, D.; Koch, W.; Krug, N.
Abstract
2015Deterministic whole-genome amplification of single cells
Czyz, Zbigniew Tadeusz; Klein, Christoph A.
Aufsatz in Buch
2015Development of a co-culture model for the prediction of idiosyncratic drug-induced liver injury
Granitzny, Anne; Hansen, Tanja; Knebel, Jan W.; Dasenbrock, Clemens; Steinberg, Pablo
Abstract
2015Development of a human organotypic tumor invasion model of cancer cell line MDA-MB-231 in Precision-Cut Lung Slices (PCLS)
Konzok, Sebastian; Schindler, Susann; Jonigk, Danny; Braubach, Peter; Braun, Armin; Sewald, Katherina
Abstract
2015Development of Biomarker Based on a Read-Across Use Case on Valproic Acid Analogues
Escher, S.; Hengstler, J.
Aufsatz in Buch
2015Development of chemical categories by optimized clustering strategies
Bitsch, Annette; Batke, Monika; Gundert-Remy, U.; Gütlein, M.; Kramer, S.; Partosch, F.; Seeland, M.
Abstract
2015Development of hematological and immunological characteristics in neonatal rats
Sewald, Katherina; Müller, Meike; Buschmann, Jochen; Hansen, Tanja; Lewin, Geertje
Zeitschriftenaufsatz, Konferenzbeitrag
2015Disease progression and changes in physical activity in patients with chronic obstructive pulmonary disease
Waschki, Benjamin; Kirsten, Anne M.; Holz, Olaf; Müller, Kai-Christian; Schaper, Miriam; Sack, Anna-Lena; Meyer, Thorsten; Rabe, Klaus F.; Magnussen, Helgo; Watz, Henrik
Zeitschriftenaufsatz
2015Effects of different blood collection methods on indicators of welfare in mice
Tsai, P.P.; Schlichtig, A.; Ziegler, E.; Ernst, H.; Haberstroh, J.; Stelzer, H.D.; Hackbarth, H.
Zeitschriftenaufsatz
2015Efficacy and safety of a novel nasal steroid, S0597, in patients with seasonal allergic rhinitis
Badorrek, Philipp; Hohlfeld, Jens M.; Krug, Norbert; Joshi, Abhijeet; Raut, Atul
Zeitschriftenaufsatz
2015Efficacy and safety of inhaled calcium lactate PUR118 in the ozone challenge model - a clinical trial
Holz, Olaf; Biller, Heike; Müller, Meike; Kane, Katie; Rosano, Molly; Hanrahan, John; Hava, David L.; Hohlfeld, Jens M.
Zeitschriftenaufsatz
2015Eosinophils of the marmoset monkey (callithrix jacchus)
Gruber-Dujardin, E.; Curths, Christoph; Bleyer, Martina; Taubert, S.; Bauer, N.; Moritz, A.; Dahlmann, Franziska; Braun, Armin; Knauf, Sascha; Kaup, Franz Josef
Abstract
2015Erste Erfahrungen mit der interdisziplinären Durchführung einer gynäko-onkologischen frühen klinischen Prüfung im neuen Clinical Research Center Hannover
May, M.; Schindler, C.; Jordan, J.; Park-Simon, T.; Hillemanns, P.
Zeitschriftenaufsatz
2015Establishment of a saline lavage model in the isolated perfused rat lung
Walter, Dorothee; Fischer, Monika; Pohlmann, Gerhard; Kemkowski, J.; Muynck, C. de; Dasenbrock, Clemens
Abstract
2015Evaluating cardiac safety of tiotropium in patients with COPD: Combined analysis of Holter-ECG data from four trials
Hohlfeld, Jens M.; Furtwängler, Armin; Könen-Bergmann, Michael; Wallenstein, Gudrun; Walter, Blate; Bateman, Eric D.
Abstract
2015Evaluation of an alternative in vitro test battery for detecting reproductive toxicants in a grouping context
Kroese, Dinant E.; Bosgra, Sieto; Buist, Harrie E.; Lewin, Geertje; Linden, Sander C. van der; Man, Hai-yen; Piersma, Aldert H.; Rorije, Emiel; Schulpen, Sjors H. W.; Schwarz, Michael; Uibel, Frederik; Vugt-Lussenburg, Barbara M.A. van; Wolterbeek, Andre P.M.; Burg, Bart van der
Zeitschriftenaufsatz
2015Evaluation of the fate and pathological response in the lung and pleura of brake dust alone and in combination with added chrysotile compared to crocidolite asbestos following short-term inhalation exposure
Bernstein, David M.; Rogers, R.A.; Sepulveda, Rosalina; Kunzendorf, Peter; Bellmann, Bernd; Ernst, Heinrich; Creutzenberg, Otto H.; Phillips, James I.
Zeitschriftenaufsatz
2015Evaluation of the toxicity and data gaps of e-cigarette aerosol
May, Martin; Schwarz, Katharina; Koch, Wolfgang; Bitsch, Annette
Abstract
2015Exacerbation of atopic dermatitis on grass pollen exposure in an environmental challenge chamber
Werfel, T.; Heratizadeh, A.; Niebuhr, M.; Kapp, A.; Roesner, L.M.; Karch, A.; Erpenbeck, V.J.; Lösche, C.; Jung, T.; Krug, N.; Badorrek, P.; Hohlfeld, J.M.
Zeitschriftenaufsatz
2015Expositionsapparat
Ritter, Detlef; Knebel, Jan
Patent
2015Features of house-dust-mite induced asthma in marmoset monkeys
Curths, C.; Dahlmann, F.; Wichmann, J.; Becker, T.; Knauf, Y.; Kaup, F.-J.; Braun, A.; Knauf, S.
Abstract
2015Foam spray application of biocides: Investigation into aerosol inhalation exposure
Schwarz, Katharina; Holthenrich, Dagmar; Bissantz, Kathrin; Ehni, Markus; Bitsch, Annette
Zeitschriftenaufsatz
2015Fraunhofer-Institut für Toxikologie und Experimentelle Medizin. Leistungen und Ergebnisse. Jahresbericht 2014
 
Jahresbericht
2015The genetic heterogeneity of circulating tumor cells: a longitudinal study in breast cancer patients
Terracciano, M.; Buson, G.; Forcato, C.; Luca, F. de; Galardi, F.; Sero, V.; Pestrin, M.; Gabellini, S.; Koestler, C.; Czyz, Z.T.; Bregola, G.; Tononi, P.; Bolognesi, C.; Fontana, F.; Medoro, G.; Polzer, B.; Leo, A. di; Klein, C.A.; Manaresi, N.
Abstract
2015A high throughput screening system for predicting chemically-induced reproductive organ deformities
Burg, Bart van der; Pieterse, Bart; Buist, Harrie E.; Lewin, Geertje; Linden, Sander C. van der; Man, Hai-yen; Rorije, Emiel; Piersma, Aldert H.; Mangelsdorf, Inge; Wolterbeek, Andre P.M.; Kroese, Dinant E.; Vugt-Lussenburg, Barbara van
Zeitschriftenaufsatz
2015House-dust-mite induced features of asthma in marmoset monkeys
Curths, Christoph; Dahlmann, Franziska; Wichmann, Judy; Becker, Tamara; Knauf, Y.; Kaup, Franz-Josef; Braun, Armin; Knauf, Sascha
Abstract
2015IBS: An illustrator for the presentation and visualization of biological sequences
Liu, Wenzhong; Xie, Yubin; Ma, Jiyong; Luo, Xiaotong; Nie, Peng; Zuo, Zhixiang; Lahrmann, Urs; Zhao, Qi; Zheng, Yueyuan; Zhao, Yong; Xue, Yu; Ren, Jian
Zeitschriftenaufsatz
2015Identification and molecular characterization of different subpopulations of EpCAM-positive single disseminated cancer cells in prostate cancer
Polzer, B.; Guzvic, M.; Ganzer, R.; Weckermann, D.; Braun, B.; Appel, I.; Obradovic, M.; Huppert, V.; Klein, C.A.
Abstract
2015Die idiopathische Lungenfibrose
Prasse, Antje
Zeitschriftenaufsatz
2015In vitro toxicity testing of two multi-walled carbon nanotubes determined for the purpose of targeted drug delivery
Requardt, Hendrik; Hansen, Tanja; Eisenbarth, E.; Hampel, S.; Dasenbrock, Clemens
Abstract
2015In vivo evaluation of a magnesium-based degradable intramedullary nailing system in a sheep model
Rössig, Christina; Angrisani, Nina; Helmecke, Patrick; Besdo, Silke; Seitz, Jan-Marten; Welke, Bastian; Fedchenko, Nickolay; Kock, Heiko; Reifenrath, Janin
Zeitschriftenaufsatz
2015Induced cytotoxicity revealed species diversity of rat and human lung tissue by repeated chemical exposure
Danov, Olga; Escher, Sylvia E.; Schröder, Katrin; Vorgrimmler, David; Braubach, Peter; Jonigk, Danny; Warnecke, Gregor; Braun, Armin; Sewald, Katherina
Abstract
2015Influence of ELF-MF on the juvenile immune system of CD-1 mice
Müller, Meike; Ziemann, Christina; Tillmann, Thomas; Lewin, Geertje; Dasenbrock, Clemens
Abstract
2015Inhalation toxicity of carbon black depends on surface coating with polycyclic aromatic hydrocarbons
Hansen, Tanja; König, P.; Creutzenberg, Otto H.; Weinhold, K.; Schlick, S.; Tillmann, Thomas; Pohlmann, Gerhard; Kolling, Angelika; Ziemann, Christina; Kopf, Johannes; Ströbele, Michael; Bockhorn, H.; Danov, Olga; Sewald, Katherina; Müller, B.; Fehrenbach, Heinz
Abstract
2015Inter- and intrasubject variability of the inflammatory response to segmental endotoxin challenge in healthy volunteers
Holz, Olaf; Tan, Lisa; Schaumann, Frank; Müller, Meike; Scholl, Dorothea; Hidi, R.; McLeod, Alison; Krug, Norbert; Hohlfeld, Jens M.
Zeitschriftenaufsatz
2015International harmonization of nomenclature and diagnostic criteria (INHAND) progress to date and future plans
Keenan, C.M.; Baker, J.F.; Bradley, A.E.; Goodman, D.G.; Harada, T.; Herbert, R.; Kaufmann, W.; Kellner, R.; Mahler, B.; Meseck, E.; Nolte, T.; Rittinghausen, S.; Vahle, J.; Yoshizawa, K.
Zeitschriftenaufsatz
2015International harmonization of nomenclature and diagnostic criteria (INHAND): Progress to date and future plans
Keenan, C.M.; Baker, J.; Bradley, A.; Goodman, D.G.; Harada, T.; Herbert, R.; Kaufmann, W.; Kellner, Rupert; Mahler, B.; Meseck, E.; Nolte, T.; Rittinghausen, Susanne; Vahle, J.; Yoshizawa, K.
Zeitschriftenaufsatz
2015Kinetic and mechanistic study of the reaction of OH radicals with methylated benzenes: 1,4-dimethyl-, 1,3,5-trimethyl-, 1,2,4,5-, 1,2,3,5- and 1,2,3,4-tetramethyl-, pentamethyl-, and hexamethylbenzene
Alarcón, P.; Bohn, B.; Zetzsch, C.
Zeitschriftenaufsatz
2015Laser microdissection of FFPE tissue areas and subsequent whole genome amplification by Ampli1™
Czyz, Zbigniew Tadeusz; Stoecklein, Nikolas H.; Polzer, Bernhard
Aufsatz in Buch
2015Longitudinal genetic characterization of circulating tumor cells in metastatic breast cancer patients
Sero, V.; Luca, F. de; Doffini, A.; Galardi, F.; Pestrin, M.; Czyz, Z.T.; Buson, G.; Bregola, G.; Bolognesi, C.; Fontana, F.; Medoro, G.; Polzer, B.; Leo, A. di; Klein, C.A.; Manaresi, N.
Abstract
2015Method and kit for determining the genome integrity and/or the quality of a library of DNA-sequences otained by deterministic restriction site whole genome amplification
Klein, Christoph Andreas; Polzer, Bernhard Michael; Manaresi, Nicolo
Patent
2015Method for identification of low soluble, biopersistent dusts (GBS) at workplaces
Creutzenberg, Otto H.; Hansen, Tanja; Schuchardt, Sven; Tillmann, Thomas
Abstract
2015Mini-Sterilisator als Alternative
Wibbertmann, Axel
Zeitschriftenaufsatz
2015Molecular characterization of early disseminating cancer cells in non-small cell lung cancer
Yamaci, R.F.; Elsner, F.; Sziklavari, Z.; Potzger, T.; Hofmann, H.S.; Klein, C.
Abstract
2015Molecular mechanisms of early cancer cell dissemination in breast cancer
Hosseini, H.; Carolin, E.L.; Nanduri, L.K.; Werno, C.; Maneck, M.; Husemann, Y.; Klein, C.A.
Abstract
2015Monitoring method for inhalation exposure to gas oil vapour and aerosol
Urbanus, J.; Banton, M.; Carter, M.; Dudzina, T.; Geudens, B.; Jones, R.; Niemeck, G.; Pizzella, G.; Tibaldi, R.; Williams, S.; Rohde, A.; Ketelslegers, H.; Berger-Preiß, E.; Koch, W.; Schuchardt, S.
Bericht
2015Multi-analyte profiling of inflammatory mediators in COPD sputum - The effects of processing
Pedersen, Frauke; Holz, Olaf; Lauer, Gereon; Quintini, Gianluca; Kiwull-Schöne, Heidrun; Kirsten, Anne-Marie; Magnussen, Helgo; Rabe, Klaus F.; Goldmann, Torsten; Watz, Henrik
Zeitschriftenaufsatz
2015Neutrophil extracellular trap formation and extracellular DNA in sputum of stable COPD patients
Pedersen, Frauke; Marwitz, Sebastian; Holz, Olaf; Kirsten, Anne; Bahmer, Thomas; Waschki, Benjamin; Magnussen, Helgo; Rabe, Klaus F.; Goldmann, Torsten; Uddin, Mohib; Watz, Henrik
Zeitschriftenaufsatz
2015New investigations into the genotoxicity of cobalt compounds and their impact on overall assessment of genotoxic risk
Kirkland, David; Brock, Tom; Haddouk, Hasnaà; Hargeaves, Victoria; Lloyd, Melvyn; Mc Garry, Sarah; Proudlock, Raymond; Sarlang, Séverine; Sewald, Katherina; Sire, Guillaume; Sokolowski, Andrea; Ziemann, Cristina
Zeitschriftenaufsatz
2015Niedrig dosierte inhalative Endotoxin Provokation bei gesunden Probanden als Modell in der klinischen Atemwegsforschung
Janssen, Ole
: Hohlfeld, Jens M. (Betreuer); Braun, Armin (Referent); Dittrich, Anna-Maria (Korreferent)
Dissertation
2015Noninvasive quantification of airway inflammation following segmental allergen challenge with functional MR imaging: A proof of concept study
Renne, Julius; Hinrichs, Jan; Schönfeld, Christian; Gutberlet, Marcel; Winkler, Carla; Faulenbach, Cornelia; Jakob, Peter; Schaumann, Frank; Krug, Norbert; Wacker, Frank; Hohlfeld, Jens M.; Vogel-Claussen, Jens
Zeitschriftenaufsatz
2015A novel human organotypic tumor invasion model of cell line MDA-MB-231 in Precision-Cut Lung Slices (PCLS) to reduce animal experiments in preclinical oncology
Konzok, Sebastian; Schindler, Susann; Jonigk, Danny; Braubach, Peter; Braun, Armin; Sewald, Katherina
Abstract
2015A novel universal allergen challenge technique for efficacy testing of immunotherapy
Schwarz, K.; Lueer, K.; Biller, H.; Windt, H.; Badorrek, P.; Hafner, D.; Koch, A.; Krug, N.; Koch, W.; Hohlfeld, J.
Abstract
2015Optimization of curation of the dataset with data on repeated dose toxicity
Gundert-Remy, Ursula; Batke, Monika; Bitsch, Annette; Gütlein, Martin; Kramer, Stefan; Partosch, Falko; Seeland, Madeleine
Abstract
2015An overview of the InhalT-90 project - a 90-day inhalation toxicity study with CeO2 nanoparticles
Schwotzer, Daniela; Hansen, Tanja; Niehof, Monika; Creutzenberg, Otto
Abstract
2015Passively sensitized human organotypic tissue as asthma model to study mast cell-nerve interaction
Jiménez Delgado, S.M.; Schindler, S.; Sewald, K.; Armin, B.
Abstract
2015Pathogen reduction by ultraviolet C light effectively inactivates human white blood cells in platelet products
Pohler, Petra; Müller, Meike; Winkler, Carla; Schaudien, Dirk; Sewald, Katherina; Müller, Thomas H.; Seltsam, Axel
Zeitschriftenaufsatz
2015Peripheral sensory nerves stimulation lead to bronchoconstriction-augment in passive sensitized human precision-cut lung slices and Is histamine 1 receptor dependent
Jiménez Delgado, Sharon Melissa; Schindler, Susann; Sewald, Katherina; Braun, Armin
Abstract
2015Personalisierte Tumortherapie
Alberter, B.; Polzer, B.
Zeitschriftenaufsatz
2015Pharmacological MRI (phMRI) of the human central nervous system
Lanfermann, Heinrich; Schindler, Chris; Jordan, Jens; Krug, Norbert; Raab, Peter
Zeitschriftenaufsatz
2015Power requirement of pressurized metered-dose and dry powder inhalers (pMDIs AND DPIs)
Haidl, P.; Pohlmann, G.; Cloes, R.M.
Abstract
2015Precision-cut lung slices as an alternative model for repeated-dose inhalation toxicity
Neuhaus, Vanessa; Danov, Olga; Witte, J.; Romberg, Susanne; Escher, Syliva; Braun, Armin; Sewald, Katherina
Abstract
2015Principles of whole-genome amplification
Czyz, Zbigniew Tadeusz; Kirsch, Stefan; Polzer, Bernhard
Aufsatz in Buch
2015Refinement and enhancement of a database for dermal absorption data
Schmeinck, Sina; Bitsch, Annette; Genth, H.
Abstract
2015Risk assessment of inhalable read-across chemicals with different mode of action showed great differences in cytotoxicity in rat and human precision-cut lung slices
Danov, Olga; Schröder, Katrin; Braubach, Peter; Jonigk, D.; Warnecke, G.; Braun, Armin; Escher, Syliva; Sewald, Katherina
Abstract
2015Safety and tolerability of a novel inhaled GATA3 mRNA targeting DNAzyme in patients with TH2-driven asthma
Homburg, Ursula; Renz, Harald; Timmer, Wolfgang; Hohlfeld, Jens M.; Seitz, Friedeborg; Lüer, Katrin; Mayer, Alexandra; Wacker, Anja; Schmidt, Oliver; Kuhlmann, Jens; Turowska, Agnieszka; Roller, Julia; Kutz, Klaus; Schlüter, Gerhard; Krug, Norbert; Garn, Holger
Zeitschriftenaufsatz
2015A saline lavage model in the isolated perfused rat lung
Walter, Dorothee; Fischer, Monika; Steinberg, Pablo; Dasenbrock, Clemens
Abstract
2015Selection of additives for reducing the toxicity of quartz in ceramic compositions
Escrig, A.; Ibanez, M.J.; Monfort, E.; Bonvicini, G.; Salomoni, A.; Creutzenberg, O.; Ziemann, C.
Zeitschriftenaufsatz
2015Serious magic-nano-like lung oedemas caused by a liquid stain protection product: Using two new tests as a combined screening tool for aerosol products
Hahn, A.; Fischer, M.; Walter, D.; Dasenbrock, C.; Koch, W.; Begemann, K.; Greiner, M.
Abstract
2015The serotonin receptor 5-HT7R regulates the morphology and migratory properties of dendritic cells
Holst, Katrin; Guseva, Daria; Schindler, Susann; Sixt, Michael; Braun, Armin; Chopra, Himpriya; Pabst, Oliver; Ponimaskin, Evgeni
Zeitschriftenaufsatz
2015The SILICOAT project
Ziemann, Christina; Rahmer, Hartmut; Escrig Vidal, A.; Bonvicini, Giuliana; Ibanez Garcia, M.J.; Monfort Gimeno, E.; Creutzenberg, Otto H.
Konferenzbeitrag, Zeitschriftenaufsatz
2015The Silicoat project: In vitro and in vivo toxicity screening of quartz varieties from ceramics industry and approaches for an effective quartz surface coating
Creutzenberg, Otto H.; Reamon-Buettner, Stella Marie; Tillmann, Thomas; Hansen, Tanja; Garcia, M.J.; Monfort, Eliseo; Bonvicini, Giuliana; Escrig, Alberto; Ziemann, Christina
Abstract
2015Single-promoter analysis of CpG and non-CpG methylation patterns in spleen of mice exposed to extremely low frequency magnetic field (ELF-MF)
Reamon-Buettner, Stella Marie; Hiemisch, Andreas; Lewin, Geertje; Dasenbrock, Clemens; Halter, Roman
Konferenzbeitrag, Zeitschriftenaufsatz
2015Species comparison of rat and human precision-cut lung slices as an alternative in risk assessment based on read-across approach
Danov, Olga; Escher, Sylvia E.; Schröder, Katrin; Vorgrimmler, David; Bersch, Claus; Braubach, Peter; Jonigk, Danny; Pfennig, Olaf; Warnecke, Gregor; Braun, Armin; Sewald, Katherina
Abstract
2015Spontaneous nonneoplastic lesions in control syrian hamsters in three 24-month long-term carcinogenicity studies
McInnes, Elizabeth F.; Ernst, Heinrich; Germann, Paul-Georg
Zeitschriftenaufsatz
2015Streptococcus pneumoniae triggers progression of pulmonary fibrosis through pneumolysin
Knippenberg, Sarah; Ueberberg, Bianca; Maus, Regina; Bohling, Jennifer; Ding, Nadine; Tort Tarres, Meritxell; Hoymann, Heinz-G.; Jonigk, Danny; Izykowski, Nicole; Paton, James C.; Ogunniyi, Abiodun D.; Lindig, Sandro; Bauer, Michael; Welte, Tobias; Seeger, Werner; Guenther, Andreas; Sisson, H. Thomas; Gauldie, Jack; Kolb, Martin; Maus, Ulrich A.
Zeitschriftenaufsatz
2015Streptococcus pneumoniae triggers progression of pulmonary fibrosis through pneumolysin
Knippenberg, Sarah; Ueberberg, Bianca; Maus, Regina; Bohling, Jennifer; Ding, Nadine; Tort Tarres, Meritxell; Hoymann, Heinz-G.; Jonigk, Danny; Izykowski, Nicole; Paton, James C.; Ogunniyi, Abiodun D.; Lindig, Sandro; Bauer, Michael; Welte, Tobias; Seeger, Werner; Guenther, Andreas; Sisson, H. Thomas; Gauldie, Jack; Kolb, Martin; Maus, Ulrich A.
Abstract
2015Structural features of endocrine active chemicals - a comparison of in vivo and in vitro data
Lewin, Geertje; Escher, Sylvia E.; Burg, Bart van der; Simetska, Nelly; Mangelsdorf, Inge
Zeitschriftenaufsatz
2015Support for the use of computer-based predictions like quantitative structure-activity relationships (QSAR methods) to avoid animal testing under REACH
Escher, Sylvia; Batke, Monika; Arning, Jürgen; Brandt, Marc; Kupper, Jürgen; Eifert, Harald; Wibbertmann, Axel
Abstract
2015Targeted expression profiling of single disseminated cancer cells isolated from bone marrow of prostate cancer patients
Guzvic, M.; Braun, B.; Ganzer, R.; Burger, M.; Nerlich, M.; Winkler, S.; Werner-Klein, M.; Czyz, Z.T.; Polzer, B.; Klein, C.A.
Abstract
2015Tiotropium respimat: Comparison of bronchodilator efficacy of 5 and 2.5 µg doses
Hohlfeld, Jens M.; Calverley, P.; Könen-Bergmann, M.; Metzdorf, N.; Bell, S.
Abstract
2015Translational models for acute respiratory injury and inflammation using precision cut lung slices
Sewald, Katherina
Abstract
2015TRPA1 agonists modulate the trachealis muscle tone via two independent mechanisms
Haider, Georg; Lee, Jae Hwa; Wiegand, Silke; Spies, Emma; Hoymann, Heinz-Gerd; Kummer, Wolfgang; Braun, Armin; Nassenstein, Christina
Abstract
2015TRPA1-Agonists: Novel bronchodilators?
Haider, G.; Lee, J.-H.; Wiegand, S.; Spies, E.; Hoymann, H.-G.; Kummer, W.; Braun, A.; Nassenstein, C.
Zeitschriftenaufsatz
2015TTC concept: Non-oral routes and influence of local effects
Escher, Sylvia E.
Abstract
2015Update of time extrapolation factors for risk assessment: The benefit of combined databases and probabilistic analyses
Escher, Sylvia E.; Hoffmann-Doerr, Simone; Pastor, Manuel; Partosch, Falko; Schröder, Katrin; Mangelsdorf, Inge
Abstract
2015The use of AOPs in risk assessment: Development of biomarker based on a read across use case on VPA analogues in the Detective project
Stöber, Werner; Steger-Hartmann, Thomas; Myatt, Glenn J.; Richarz, Andrea; Hengstler, Jan; Escher, Sylvia E.
Abstract
2015Use of ex vivo organotypic lung tissue in translational research of respiratory injury and inflammation diseases
Sewald, Katherina
Abstract
2015VPA Read across: Development of predictive biomarkers by using toxicity data of structurally similar compounds
Stöber, Regina; Escher, Sylvia E.; Hengstler, Jan G.
Abstract
20141. Welche Auswirkung hat "Hungern" in Toxizitätsstudien mit wiederholter Verabreichung? 2. Prädiktivität von Organgewichten - Organgewicht als Biomarker in der Toxikologie?
Schweiger, Julietta Ursula
: Escher, Sylvia (1. Gutachter); Stahlmann, Ralf (2. Gutachter)
Master Thesis
2014Airway hyper-responsiveness in lipopolysaccharide-challenged common marmosets (Callithrix jacchus)
Curths, Christoph; Wichmann, Judy; Dunker, Sarah; Windt, Horst; Hoymann, Heinz-Gerd; Lauenstein, Hans D.; Hohlfeld, Jens M.; Becker, Tamara; Kaup, Franz-Josef; Braun, Armin; Knauf, Sascha
Zeitschriftenaufsatz
2014Allergic airway inflammation induces the migration of dendritic cells into airway sensory ganglia
Le, D.D.; Rochlitzer, S.; Fischer, A.; Heck, S.; Tschernig, T.; Sester, M.; Bals, R.; Welte, T.; Braun, A.; Dinh, Q.T.
Zeitschriftenaufsatz
2014Allergische Atemwegsentzündung induziert eine Zunahme von Dendritischen Zellen in den Atemwegsganglien der Maus
Le, Duc Dung; Rochlitzer, Sabine; Heck, Sebastian; Bals, Robert; Braun, Armin; Welte, Tobias; Dinh, Quoc Thai
Abstract
2014Alternative model for repeated dose inhalation toxicity using precision-cut lung slices
Neuhaus, Vanessa; Danov, Olga; Witte, J.; Romberg, Susanne; Escher, Sylvia; Schaudien, Dirk; Braun, Armin; Sewald, Katherina
Abstract
2014Analysing reproductive toxicity studies using the FeDTex database - does an F2-generation provide an additional benefit?
Schulz, Florian; Lewin, Geertje; Mangelsdorf, Inge; Batke, Monika; Escher, Sylvia
Zeitschriftenaufsatz, Konferenzbeitrag
2014Analysis of nucleic acids in single cells
Kirsch, Stefan; Polzer, Bernhard; Klein, Christoph A.
Aufsatz in Buch
2014Analyzing dermal absorption data of chemicals
Scholz, Roland; Hahn, Stefan; Bitsch, Annette
Zeitschriftenaufsatz, Konferenzbeitrag
2014Applications of lp-norms and their smooth approximations for gradient based learning vector quantization
Lange, M.; Zühlke, D.; Holz, O.; Villmann, T.
Konferenzbeitrag
2014Applications of NMR techniques for the identification and structure elucidation of emerging organic and other xenobiotic organic contaminants
Preiß, Alfred; Godejohann, Markus
Aufsatz in Buch
2014Assessment of immunotoxicity induced by chemicals in human precision-cut lung slices (PCLS)
Lauenstein, L.; Switalla, S.; Prenzler, F.; Seehase, S.; Pfennig, O.; Förster, C.; Fieguth, H.; Braun, A.; Sewald, K.
Zeitschriftenaufsatz
2014Biological effects of inhalable compounds improvements of the in vitro testing method
Ritter, Detlef; Knebel, Jan; Brodbeck, Carsten; Javala, Pasi
Abstract
2014Biological effects of inhalable substances - development of a concept to standardize in vitro studies using aerosols
Ritter, Detlef; Arndt, Hendrik; Knebel, Jan
Zeitschriftenaufsatz, Konferenzbeitrag
2014Biological impact of modified inhalable carbon black nanoparticles assessed in cell and tissue culture models
Danov, Olga; Kopf, Johannes; Ströbele, M.; Bockhorn, H.; Fehrenbach, H.; Braun, Armin; Sewald, Katherina; Hansen, Tanja
Abstract
2014Biomarker for eosinophil and T-cell recruitment induced by interleukin-13 as a therapeutic target for allergic asthma tested in human precision-cut lung slices
Danov, Olga; Jiménez Delgado, Sharon Melissa; Drake, H.; Pfennig, Olaf; Förster, C.; Hohlbaum, A.; Audoly, L.; Braun, Armin; Sewald, Katherina
Abstract
2014Biotechnologie statt Tierversuche
Braun, Armin
Zeitschriftenaufsatz
2014BrdU screening - a short-time test for reliable prediction of carcinogenicity for MWCNT
Hackbarth, Anja; Schaudien, Dirk; Bellmann, Bernd; Ernst, Heinrich; Leonhardt, Albrecht; Heinrich, Uwe; Rittinghausen, Susanne
Abstract
2014BrdU screening - short-time test for reliable prediction of carcinogenicity for MWCNT
Hackbarth, Anja; Schaudien, Dirk; Bellmann, Bernd; Ernst, Heinrich; Leonhardt, Albrecht; Steinberg, Pablo; Rittinghausen, Susanne
Zeitschriftenaufsatz, Konferenzbeitrag
2014Building up a co-culture and surfactant model for routine use in ali exposures
Javala, Pasi; Ritter, Detlef; Knebel, Jan
Abstract
2014The carcinogenic effect of various multi-walled carbon nanotubes (MWCNTs) after intraperitoneal injection in rats
Rittinghausen, Susanne; Hackbarth, Anja; Creutzenberg, Otto; Ernst, Heinrich; Heinrich, Uwe; Leonhardt, Albrecht; Schaudien, Dirk
Zeitschriftenaufsatz
2014Carcinogenicity and mutagenicity of nanoparticles - assessment of current knowledge as basis for regulation
Schröder, Katrin; Polenz-Michel, Christina; Simetska, Nelly; Voss, Jens-Uwe; Escher, Sylvia; Mangelsdorf, Inge
Bericht
2014CEFIC-LRI N1 project: Genotoxicity of a synthetic amorphous silica (SAS) in rats
Knebel, Jan; Ziemann, Christina; Creutzenberg, Otto H.
Abstract
2014CEFIC-LRI N1 Project: Inhalation toxicity of a synthetic amorphous silica (SAS) in rats
Creutzenberg, Otto H.; Pohlmann, Gerhard; Hansen, Tanja; Schuchardt, Sven; Ernst, Heinrich; Tillmann, Thomas; Schaudien, Dirk
Abstract
2014CEFIC-LRI N1 Project: Oral toxicity of a synthetic amorphous silica (SAS) in rats
Buschmann, Jochen; Lewin, Geertje; Creutzenberg, Otto H.
Abstract
2014Cell counting in human endobronchial biopsies - disagreement of 2D versus 3D morphometry
Bratu, Vlad A.; Erpenbeck, Veit J.; Fehrenbach, Antonia; Rausch, Tanja; Rittinghausen, Susanne; Krug, Norbert; Hohlfeld, Jens M.; Fehrenbach, Heinz
Zeitschriftenaufsatz
2014Characterization of ex vivo immunostimulated dendritic cells in murine lung tissue
Brandstetter, Ronja Lorena
: Braun, Armin (Gutachter); Schwinzer, Reinhard (Gutachter)
Master Thesis
2014Characterization of IL-13- and allergen-induced airway hyperreactivity in precision-cut lung slices of different species
Drake, Helena
: Förster, Irmgard (Supervisor); Burgdorf, Sven (Supervisor); Sewald, Katherina (Advisor); Braun, Armin (Advisor)
Master Thesis
2014The ChemScreen project to design a pragmatic alternative approach to predict reproductive toxicity of chemicals
Burg, B. van der; Bay Wedebye, E.; Dietrich, D.R.; Jaworska, J.; Mangelsdorf, Inge; Paune, E.; Schwarz, M.; Piersma, A.H.; Kroese, E.D.
Abstract
2014Combined genome and transcriptome analysis of single disseminated cancer cells from bone marrow of prostate cancer patients reveals unexpected transcriptomes
Guzvic, Miodrag; Braun, Bernhard; Ganzer, Roman; Burger, Maximilian; Nerlich, Michael; Winkler, Sebastian; Werner-Klein, Melanie; Czyz, Zbigniew T.; Polzer, Bernhard; Klein, Christoph A.
Zeitschriftenaufsatz
2014Comparison of two different application routes of nanosilver in rats - a toxicokinetic study
Horzowski, Sabine; Lichtenstein, Dajana; Potkura, Jana; Oberemm, Axel; Creutzenberg, Otto; Lampen, Alfonso
Abstract
2014Correlations between different endpoints in repeated dose toxicity studies: Occurrence of dependent and independent effects at equal dose levels in the RepDose and the "ELINCS" database
Batke, Monika; Bitsch, Annette; Gundert-Remy, Ursula; Gütlein, Martin; Kramer, Stefan; Partosch, Falko; Seeland, Madeleine; Stahlmann, Ralf
Zeitschriftenaufsatz, Konferenzbeitrag
2014Cytochrome P450 monooxygenases expression in human bronchial epithelial calu-3 cells under different culture conditions
Hansen, Tanja; Niehof, Monika; Knebel, Jan
Abstract
2014Data-mining in toxicology
Mangelsdorf, I.
Aufsatz in Buch
2014Dermal exposure
Mangelsdorf, Inge; Schröder, Katrin; Costa Pinheiro, Nathalie
Buch
2014Development of an in silico pre-screen for reproductive toxicity within the EU project ChemScreen
Lewin, Geertje; Burg, Bart van der; Batke, Monika; Escher, Sylvia; Mangelsdorf, Inge
Zeitschriftenaufsatz, Konferenzbeitrag
2014Development of chemical categories by optimized clustering strategies
Batke, Monika; Bitsch, Annette; Gundert-Remy, Ursula; Gütlein, Martin; Helma, Christoph; Kramer, Stefan; Maunz, Andreas; Partosch, Falko; Seeland, Madeleine; Stahlmann, Ralf
Zeitschriftenaufsatz, Konferenzbeitrag
2014Diamide does not improve the analysis of IL1b and TNFa in dithiothreitol-treated sputum supernatants
Holz, Olaf; Lavae-Mokhtari, Bianca; Witte, Lena; Hohlfeld, Jens Michael
Abstract
2014Distribution of ciliated epithelial cells in the trachea of common marmosets (Callithrix jacchus)
Hoffmann, R.; Braun, A.; Knauf, S.; Kaup, F.-J.; Bleyer, M.
Zeitschriftenaufsatz
2014Does foam application reduce aerosol formation?
Bitsch, Annette; Schwarz, Katherina; Hahn, Stefan; Ehni, M.; Holthenrich, D.; Koch, W.
Abstract
2014Dose-range finding of natural birch pollen exposure in patients with seasonal allergic rhinitis in the Fraunhofer Environmental Challenge Chamber
Lüer, Katrin; Windt, Horst; Schwarz, Katharina; Badorrek, Philipp; Sebastian, Ramona; Haefner, Dietrich; Koch, Wolfgang; Krug, Norbert; Hohlfeld, Jens Michael
Abstract
2014The effect of controlled exposure to grass pollen in an environmental challenge chamber on dermal symptoms in patients with atopic dermatitis
Heratizadeh, Annice; Badorrek, Philipp; Niebuhr, Margarete; Erpenbeck, Veit Johannes; Lösche, C.; Krug, Norbert; Hohlfeld, Jens Michael; Werfel, Thomas
Abstract
2014The effect of flow rate on the level of volatile organic compounds (voc) in exhaled breath
Holz, Olaf; Gaida, Arne; Schuchardt, Sven; Langejuergen, Jens; Zimmermann, Stefan; Hohlfeld, Jens Michael
Abstract
2014Effect of sample processing on the analysis of IL4, IL5, and IL13 in sputum supernatants
Holz, Olaf; Müller, Meike; Ignatenko, Stanislav; Kappeler, Dominik; Buhl, Roland; Beeh, Kai-Michael; Kornmann, Oliver; Kirsten, Anne; Homburg, Ursula; Garn, Holger; Krug, Norbert; Hohlfeld, Jens Michael
Abstract
2014Effects of ultrafine particles on the allergic inflammation in the lung of asthmatics: Results of a double-blinded randomized cross-over clinical pilot study
Schaumann, Frank; Frömke, Cornelia; Dijkstra, Dorothea; Alessandrini, Francesca; Windt, Horst; Karg, Erwin; Müller, Meike; Winkler, Carla; Braun, Armin; Koch, Armin; Hohlfeld, Jens Michael; Behrendt, Heidrun; Schmid, Othmar; Koch, Wolfgang; Schulz, Holger; Krug, Norbert
Zeitschriftenaufsatz
2014Efficacy of the oral chemoattractant receptor homologous molecule on TH2 cells antagonist BI 671800 in patients with seasonal allergic rhinitis
Krug, Norbert; Gupta, Abhy; Badorrek, Philipp; Koennen, Ruediger; Mueller, Meike; Pivovarova, Anna; Hilbert, James; Wetzel, Kristiane; Hohlfeld, Jens M.; Wood, Chester
Zeitschriftenaufsatz
2014Efficiency improvement of an antibody production process by increasing the inoculum density
Hecht, V.; Duvar, S.; Ziehr, H.; Burg, J.; Jockwer, A.
Zeitschriftenaufsatz
2014Einzelzell Heterogenität von Melanomsphären generiert aus disseminierten Tumorzellen
Sadlers, Sabine Jennifer
: Rosenau, Frank (Gutachter); Polzer, Bernhard (Gutachter); Hennes, Kilian (Zweitprüfer)
Master Thesis
2014Entwicklung eines Assays zu Qualitätskontrolle von Whole Transcriptome Amplifications
Ganser, Iris
: Klein, Christoph A. (Betreuer)
Bachelor Thesis
2014Entwicklung eines Rhinovirus-Infektionsmodells in Precision-cut lung slices
Romberg, Susanne
: Lübke, Torben (Gutachter); Fischer von Mollard, Gabriele (Gutachter); Dasenbrock, Clemens (Zweitprüfer)
Master Thesis
2014Environmental risk assessment of veterinary pharmaceuticals
Könnecker, Gustav; Krome, Kristin
Zeitschriftenaufsatz
2014Establishment of a saline lavage model in the isolated perfused rat lung
Walter, Dorothee; Fischer, Monika; Dasenbrock, Clemens
Abstract
2014Establishment of pathway-specific gene expression analysis using the example of the paraquat action on human lung epithelial cells
Niehof, Monika; Augustin, Christian; Hansen, Tanja
Zeitschriftenaufsatz, Konferenzbeitrag
2014Etablierung eines Modellsystems mit Aerosolen zur Charakterisierung von Expositionssystemen für die Untersuchung inhalierbarer Substanzen in vitro
Arndt, Hendrik
: Walker, Gottfried (Erstprüfer); Knebel, Jan W. (Zweitprüfer)
Bachelor Thesis
2014Etablierung eines Pseudomonas aeruginosa Biofilmassays zur Antibiotikawirksamkeitstestung
Donath, Mandy
: Schierack, Peter (Gutachter); Rochlitzer, Sabine (Gutachter)
Bachelor Thesis
2014Evaluation of small molecule FRET reporter for the diagnosis and monitoring of proteolytic activity in a chronic obstructive lung disease model
Reither, G.; Heath, N.; Holz, Olaf; Kahn, N.; Hohlfeld, Jens Michael; Schulz, C.; Mall, M.A.
Abstract
2014The evaluation of the biopersistence, pathological response, and pleural translocation of chrysotile containing brake dust in comparison to crocidolite asbestos following short-term inhalation exposure
Bernstein, David M.; Rogers, R.A.; Ernst, Heinrich; Phillips, J.I.
Abstract
2014Evaluation of the deposition, translocation and pathological response of brake dust with and without added chrysotile in comparison to crocidolite asbestos following short-term inhalation: Interim results
Bernstein, David M.; Rogers, Rick; Sepulveda, Rosalina; Kunzendorf, Peter; Bellmann, Bernd; Ernst, Heinrich; Phillips, James I.
Zeitschriftenaufsatz
2014Ex vivo models for asthma, COPD and lung injury in precision cut lung slices (PCLS)
Sewald, Katherina; Braun, Armin
Abstract
2014Exercise challenge amplifies differences in metabolomic signals between healthy smokers and smokers with COPD (gold2)
Holz, Olaf; Roepcke, Stefan; Lauer, Gereon; Elmlinger, Martin; Lahu, Gezim; Hohlfeld, Jens Michael
Abstract
2014Fraunhofer-Institut für Toxikologie und Experimentelle Medizin. Leistungen und Ergebnisse. Jahresbericht 2013
 
Jahresbericht
2014Frühe Phase der Allergen-induzierten Atemwegsreaktion beim Weißbüschelaffen nach passiver Sensibilisierung von Lungengewebe mit humanem Blutplasma
Wichmann, Judy; Jiménez Delgado, Sharon Melissa; Curths, Christoph; Becker, Tamara; Kaup, Franz Josef; Braun, Armin; Sewald, Katherina; Knauf, Sascha
Abstract
2014Fundamental improvements of the air-liquid interface technique for use in in vitro inhalation toxicology
Knebel, Jan; Ritter, Detlef; Brodbeck, Carsten
Abstract
2014Gastrointestinal absorption processes of substances: Do they have an impact on bioaccumulation?
Zwintscher, Ariane; Hahn, Stefan; Kühne, R.; Schuurmann, G.; Drost, W.; Ackermann, J.; Joehncke, U.; Schlechtriem, C.; Nendza, M.
Abstract
2014Genomic high-resolution profiling of single CKpos/CD45neg flow-sorting purified circulating tumor cells from patients with metastatic breast cancer
Neves, Rui P.L.; Raba, Katharina; Schmidt, Oliver; Honisch, Ellen; Meier-Stiegen, Franziska; Behrens, Bianca; Möhlendick, Birte; Fehm, Tanja; Neubauer, Hans; Klein, Christoph A.; Polzer, Bernhard; Sproll, Christoph; Fischer, Johannes C.; Niederacher, Dieter; Stoecklein, Nikolas H.
Zeitschriftenaufsatz
2014Histopathological analysis of malignant tumors induced by intraperitoneal injection of carbon nanotubes
Rittinghausen, Susanne; Bellmann, Bernd; Hackbarth, Anja; Ernst, Heinrich; Heinrich, Uwe; Leonhardt, A.; Schaudien, Dirk
Abstract
2014A human in vitro allergy model showing allergen specific immune responses using house dust mite or grass pollen allergen
Müller, Meike; Schaumann, Frank; Braun, Armin
Abstract
2014Human medicinal products: Environmental risk assessment for volatile anaesthetics
Krome, Kristin; Hahn, Stefan; Schwonbeck, Susanne; Könnecker, Gustav; Licht, Oliver
Zeitschriftenaufsatz, Konferenzbeitrag
2014Human organotypic cancer model
Konzok, Sebastian; Schindler, Susann; Braun, Armin; Sewald, Katherina
Abstract
2014Identification and quantification of basophils in the airways of asthmatics following segmental allergen challenge
Dijkstra, D.; Hennig, C.; Hansen, G.; Biller, H.; Krug, N.; Hohlfeld, J.M.
Zeitschriftenaufsatz
2014Identifying placental epigenetic alterations in an intrauterine growth restriction (IUGR) rat model induced by gestational protein deficiency
Reamon-Büttner, Stella Marie; Buschmann, Jochen; Lewin, Geertje
Zeitschriftenaufsatz
2014IL-13 induced asthma model in human precision-cut lung slices
Danov, Olga; Jiménez Delgado, Sharon Melissa; Drake, H.; Seehase, Sophie; Hohlbaum, A.M.; Bersch, C.; Jonigk, D.; Warnecke, G.; Braun, Armin; Sewald, Katherina
Abstract
2014Immune humanization of immunodeficient mice using diagnostic bone marrow aspirates from carcinoma patients
Werner-Klein, Melanie; Proske, Judith; Werno, Christian; Schneider, Katharina; Hofmann, Hans-Stefan; Rack, Brigitte; Buchholz, Stefan; Ganzer, Roman; Blana, Andreas; Seelbach-Göbel, Birgit; Nitsche, Ulrich; Männel, Daniela N.; Klein, Christoph A.
Zeitschriftenaufsatz
2014Impact of a Met(11)Thr single nucleotide polymorphism of surfactant protein D on allergic airway inflammation in a murine asthma model
Winkler, C.; Bahlmann, O.; Viereck, J.; Knudsen, L.; Wedekind, D.; Hoymann, H.G.; Madsen, J.; Thum, T.; Hohlfeld, J.M.; Ochs, M.
Zeitschriftenaufsatz
2014Impact of endobronchial allergen provocation on macrophage phenotype in asthmatics
Winkler, C.; Witte, L.; Moraw, N.; Faulenbach, C.; Müller, M.; Holz, O.; Schaumann, F.; Hohlfeld, J.M.
Zeitschriftenaufsatz
2014Improvement of the TTC concept for oral and inhalation exposure and its application in an Integrated Testing Strategy (ITS) for the endpoint repeated-dose toxicity
Tluczkiewicz, Inga
: Schüürmann, Gerrit (Supervisor); Escher, Sylvia (Advisor)
Dissertation
2014Improvements of the ALI in vitro testing method for inhalable compounds
Ritter, Detlef; Knebel, Jan; Brodbeck, Carsten
Abstract
2014Incorporating potency into EU classification for carcinogenicity and reproductive toxicity
Hennes, C.; Batke, Monika; Bomann, W.; DuHayon, S.; Kosemund, K.; Politano, V.; Stinchcombe, S.; Doe, J.
Zeitschriftenaufsatz
2014Inhalation toxicity of nanoparticle-based aerosols
Gessner, Isabel
: Mathur, Sanjay (Betreuer); Knebel, Jan W. (Betreuer); Dasenbrock, Clemens (Zweitprüfer)
Master Thesis
2014Interleukin-13 as a therapeutic target for allergic asthma tested in human precision-cut lung slices
Danov, Olga; Jiménez Delgado, Sharon Melissa; Pfennig, Olaf; Forster, Christine; Hohlbaum, Andreas; Audoly, Laurent; Braun, Armin; Sewald, Katherina
Abstract
2014Invasion, proliferation and influence of cancer cell line MDA-MB-231 on organotypic tissue using Precision Cut Lung Slices (PCLS)
Konzok, Sebastian
: Braun, Armin (Supervisor); Tamura-Niemann, Teruko (Supervisor)
Master Thesis
2014Invasive but repetitive lung function measurements in a rodent model of pulmonary fibrosis
Hoymann, Heinz-Gerd; Ernst, Heinrich; Creutzenberg, Otto H.; Schaudien, Dirk; Müller, Meike; Knudsen, Lars; Braun, Armin
Abstract
2014Investigations of the biological effects of airborne and inhalable substances by cell-based in vitro methods
Ritter, Detlef; Knebel, Jan
Zeitschriftenaufsatz
2014Isolation and cultivation of metabolically competent alveolar epithelial cells from A/J mice
Hansen, T.; Chougule, A.; Borlak, J.
Zeitschriftenaufsatz
2014A k-NN algorithm for predicting oral sub-chronic toxicity in the rat
Gadaleta, Domenico; Pizzo, Fabiola; Lombardo, Anna; Carotti, Angelo; Escher, Sylvia E.; Nicolotti, Orazio; Benfenati, Emilio
Zeitschriftenaufsatz
2014Kinetikanalysen des Aktivierungszustandes von ex vivo stimulierten dendritischen Zellen im murinen PCLS Modell
Baron, Lena
: Braun, Armin (1. Gutachter); Schwinzer, Reinhard (2. Gutachter)
Master Thesis
2014Lack of marked cyto- and genotoxicity of cristobalite in devitrified (heated) alkaline earth silicate wools in short-term assays with cultured primary rat alveolar macrophages
Ziemann, Christina; Harrison, Paul T.C.; Bellmann, Bernd; Brown, Robert C.; Zoitos, Bruce K.; Class, Philippe
Zeitschriftenaufsatz
2014Longitudinal measurement of airway inflammation over one year in children and adults with intermittent asthma
Holz, Olaf; Pedersen, Frauke; Kanniess, Frank; Zielen, Stefan; Gillissen, Adrian; Berg, Andrea von; Berdel, Dietrich; Schnoor, Maike; Magnussen, Helgo
Abstract
2014Longitudinal measurement of airway inflammation over one year in children and adults with intermittent asthma
Pedersen, F.; Holz, O.; Kanniess, F.; Zielen, S.; Schulze, J.; Gillissen, A.; Berg, A. von; Berdel, D.; Beier, J.; Beeh, K.; Schnoor, M.; Magnussen, H.
Zeitschriftenaufsatz
2014Lung function assessment in nonhuman primate models of obstructive pulmonary diseases
Curths, Christoph; Wichmann, Judy; Becker, Tamara; Kaup, Franz-Josef; Hohlfeld, Jens Michael; Windt, Horst; Dunker, Sarah; Hoymann, Heinz-Gerd; Braun, Armin; Knauf, Sascha
Abstract
2014Lung function assessment in the common marmoset (Callithrix jacchus) for the evaluation of translational nonhuman primate models of lung inflammation
Curths, Christoph; Wichmann, Judy; Becker, Tamara; Kaup, Franz Josef; Hohlfeld, Jens Michael; Windt, Horst; Dunker, Sarah; Hoymann, Heinz Gerd; Braun, Armin; Knauf, Sascha
Abstract
2014Lung tissue culture model for assessment of cytotoxicity and inflammation induced by inhalable carbon black nanoparticles
Braun, Armin; Danov, Olga; Kopf, Johannes Claudius; Ströbele, Michael; Hansen, Tanja; Fehrenbach, Heinz; Sewald, Katherina
Abstract
2014Lymph nodes
Kuper, Frieke C.; Schaudien, Dirk; Parker, George
Aufsatz in Buch
2014Lymphoid tissue and pathological influences of toxicants
Schaudien, Dirk; Harleman, H.; Bouallala, F.; Kuper, C.F.
Aufsatz in Buch
2014A model of neuronal hyperreactivity in passive sensitized human organotypic tissue
Schindler, Susann; Jiménez Delgado, Sharon Melissa; Braun, Armin
Abstract
2014Molecular profiling of single circulating tumor cells with diagnostic intention
Polzer, Bernhard; Medoro, Gianni; Pasch, Sophie; Fontana, Francesca; Zorzino, Laura; Pestka, Aurelia; Andergassen, Ulrich; Meier-Stiegen, Franziska; Czyz, Zbigniew T.; Alberter, Barbara; Treitschke, Steffi; Schamberger, Thomas; Sergio, Maximilian; Bregola, Giulia; Doffini, Anna; Gianni, Stefano; Calanca, Alex; Signorini, Giulio; Bolognesi, Chiara; Hartmann, Arndt; Fasching, Peter A.; Sandri, Maria T.; Rack, Brigitte; Fehm, Tanja; Giorgini, Guiseppe; Manaresi, Nicolò; Klein, Christoph A.
Zeitschriftenaufsatz
2014Multi-Label-Classification to predict repeated dose toxicity in the context of REACH
Batke, Monika; Bitsch, Annette; Gundert-Remy, Ursula; Gütlein, Martin; Helma, Christoph; Kramer, Stefan; Maunz, Andreas; Partosch, Falko; Seeland, Madeleine; Stahlmann, Ralf
Zeitschriftenaufsatz, Konferenzbeitrag
2014Multiwalled carbon nanotubes (MWCNT) induce DNA damage and cellular senescence in human peritoneal mesothelial LP9 cells
Reamon-Büttner, Stella Marie; Bellmann, Bernd; Hackbarth, Anja; Leonhardt, Albrecht; Niehof, Monika; Ziemann, Christina
Zeitschriftenaufsatz, Konferenzbeitrag
2014Murine precision-cut liver slices (PCLS): A new tool for studying tumor microenvironments and cell signaling ex vivo
Koch, Alexandra; Saran, Shashank; Tran, Doan Duy Hai; Klebba-Färber, Sabine; Thiesler, Hauke; Sewald, Katherina; Schindler, Susann; Braun, Armin; Klopfleisch, Robert; Tamura, Teruko
Zeitschriftenaufsatz
2014Nanoparticles and pop-off technique for electron microscopy: A known technique for a new purpose
Lehmbecker, Annika; Rittinghausen, Susanne; Rohn, Kerstin; Baumgärtner, Wolfgang; Schaudien, Dirk
Zeitschriftenaufsatz
2014Neuronale Plastizität in NGF-transgenen Mäusen bei allergischen Atemwegentzündungen
Dinh, Quoc Thai; Quarcoo, David; Braun, Armin; Welte, Tobias; Bals, Robert; Fischer, A.
Abstract
2014A new adjuvanted nanoparticle-based H1N1 influenza vaccine induced antigen-specific local mucosal and systemic immune responses after administration into the lung
Neuhaus, Vanessa; Chichester, Jessica A.; Ebensen, Thomas; Schwarz, Katharina; Cartman, Caitlin E.; Shoji, Yoko; Guzman, Carlos A.; Yusibov, Vidadi; Sewald, Katherina; Braun, Armin
Zeitschriftenaufsatz
2014New treatment strategies for respiratory diseases: Ex vivo and in vivo evaluation of pharmacological immunomodulations using a nanoparticle-based drug delivery system
Neuhaus, Vanessa
: Braun, Armin (Supervisor); Dittrich, Anna-Maria (Cosupervisor); Müller-Goymann, Christel (Cosupervisor)
Dissertation
2014No exacerbation but impaired anti-viral mechanisms in a rhinovirus-chronic allergic asthma mouse model
Rochlitzer, Sabine; Hoymann, Heinz-Gerd; Müller, Meike; Braun, Armin
Zeitschriftenaufsatz
2014Numerical study of the RespiCon sampler performance in the calm air
Zaripov, S.; Koch, W.
Zeitschriftenaufsatz
2014Omalizumab in patients with allergic (IgE-mediated) asthma and IgE/bodyweight combinations above those in the initially approved dosing table
Kornmann, Oliver; Watz, Henrik; Fuhr, Rainard; Krug, Norbert; Erpenbeck, Veit J.; Kaiser, Guenther
Zeitschriftenaufsatz
2014Optimizing gene-expression analysis for induced sputum
Holz, Olaf; Hansen, Tanja; Homburg, Ursula; Garn, Holger; Hohlfeld, Jens Michael; Niehof, Monika
Abstract
2014Passively sensitized precision-cut lung slices from marmoset monkeys as a preclinical assay to test novel IgE inhibitors
Wichmann, Judy; Jiménez Delgado, Sharon Melissa; Curths, Christoph; Becker, Tamara; Eggel, Alexander; Kaup, Franz-Josef; Braun, Armin; Sewald, Katherina; Knauf, Sascha
Abstract
2014Pharmacokinetics and pharmacodynamics of tiotropium solution and tiotropium powder in chronic obstructive pulmonary disease
Hohlfeld, Jens M.; Sharma, A.; Noord, J.A. van; Cornelissen, P.J.; Derom, E.; Towse, L.; Peterkin, V.; Disse, B.
Zeitschriftenaufsatz
2014Phase-contrast MRI for detection of mild systemic hemodynamic response after segmental allergen challenge in asthmatic patients
Hinrichs, Jan; Schaumann, Frank; Renne, Julius; Schönfeld, Christian; Faulenbach, Cornelia; Winkler, Carla; Gutberlet, Marcel; Krug, Norbert; Wacker, Frank; Hohlfeld, Jens M.; Vogel-Claussen, Jens
Zeitschriftenaufsatz
2014Potential prognostic value of biomarkers in lavage, sputum and serum in a five year clinical follow-up of smokers with and without COPD
Holz, Olaf; Waschki, Benjamin; Roepcke, Stefan; Watz, Henrik; Lauer, Gereon; Faulenbach, Cornelia; Hohlfeld, Jens M.
Zeitschriftenaufsatz
2014Pre-validation of the ex vivo model precision-cut lung slices (PCLS) for prediction of acute inhalation toxicity
Sewald, Katherina; Lauenstein, Lan; Schneider, X.; Pirow, R.; Steinfath, M.; Ma-Hock, L.; Liebsch, M.; Landsiedel, R.; Braun, Armin; Martin, C.
Abstract
2014Precision-cut lung slices as alternative to mimic inflammation, lung injury and bronchoconstriction after short and long-term maintenance in culture
Neuhaus, Vanessa; Schaudien, Dirk; Sewald, Katherina; Braun, Armin
Abstract
2014Predicted no effect concentration derivation as a significant source of variability in environmental hazard assessments of chemicals in aquatic systems: An international analysis
Hahn, Torsten; Diamond, Jerry; Doubson, Stuart; Howe, Paul; Kielhorn, Janet; Könnecker, Gustav; Lee-Steere, Chris; Mangelsdorfg, Inge; Schneider, Uwe; Sugaya, Yoshio; Taylor, Ken; Van Dam, Rick; Stauber, Jenny L.
Zeitschriftenaufsatz
2014Prevalence and phenotypic characteristics of severe adult-onset asthma in the U-Biopred cohort
Hekking, Pieter-Paul; Wagener, Ariane H.; Sousa, Ana R.; Fowler, Stephen J.; Bakke, Per; Frey, Urs; Krug, Norbert; Hashimoto, Simone; Woodcock, Ashley; Chanez, Pascal; Montuschi, Paolo; Bisgaard, Hans; Corfield, Julie; Howarth, Peter H.; Djukanovic, Ratko; Chung, Kian Fan; Fleming, Louise; Riley, John; Jeyasingham, Elisabeth; Fichtner, Klaus; Rowe, Anthony; Roberts, Graham; Singer, Florian; Geiser, Thomas; Horvath, Ildiko; Riccardo, Polosa; Vissing, Nadja H.; Dahlen, Babro; Musial, Jacek; Murray, Clare S.; Myles, David; Compton, Chris; Higenbottam, Tim W.; Vestbo, J.; Pahus, Laurie; Larsson, Lars; Sandstrom, Thomas; Shaw, Dominic; Wagers, Scott S.; Sterk, Peter J.; Bansal, Aruna T.; Bel, Elisabeth
Abstract
2014Prevalidation of the ex vivo model PCLS for the prediction of acute inhalation toxicity
Sewald, Katherina; Hess, A.; Lauenstein, Lan; Schneider, X.; Vogel, S.; Steinfath, M.; Pirow, R.; Liebsch, M.; Kolle, S.; Ma-Hock, L.; Landsiedel, R.; Martin, C.; Braun, Armin
Abstract
2014Promises and challenges in constructing an adverse outcome pathway for chemical sensitization of the respiratory tract
Sullivan, K.; Cochrane, S.; Enoch, S.; Kimber, I.; Patlewicz, G.; Roggen, E.; Sewald, Katherina; Ezendam, J.
Abstract
2014Prostaglandin D2-supplemented "functional eicosanoid testing and typing" assay with peripheral blood leukocytes as a new tool in the diagnosis of systemic mast cell activation disease
Schäfer, Dirk; Dreßen, Peter; Brettner, Stefan; Rath, Norbert-Folke; Molderings, Gerhard J.; Jensen, Katrin; Ziemann, Christina
Zeitschriftenaufsatz
2014Quantification of pulmonary inflammation after segmental allergen challenge using turbo-inversion recovery-magnitude magnetic resonance imaging
Vogel-Claussen, Jens; Renne, Julius; Hinrichs, Jan; Schönfeld Christian; Gutberlet, Marcel; Schaumann, Frank; Winkler, Carla; Faulenbach, Cornelia; Krug, Norbert; Wacker, Frank; Hohlfeld, Jens Michael
Zeitschriftenaufsatz
2014Quantitative measurement of melanoma spread in sentinel lymph nodes and survival
Ulmer, A.; Dietz, K.; Hodak, I.; Polzer, B.; Scheitler, S.; Yildiz, M.; Czyz, Z.; Lehnert, P.; Fehm, T.; Hafner, C.; Schanz, S.; Röcken, M.; Garbe, C.; Breuninger, H.; Fierlbeck, G.; Klein, C.A.
Zeitschriftenaufsatz
2014Refinement of acute inhalation toxicity studies: The isolated perfused rat lung as a screening tool for surface-active substances
Fischer, Monika; Dasenbrock, Clemens; Windt, Horst; Koch, Wolfgang
Zeitschriftenaufsatz, Konferenzbeitrag
2014Refinement of acute inhalation toxicity studies: The isolated perfused rat lung as a screening tool for surface-active substances
Dasenbrock, Clemens; Fischer, Monika; Windt, Horst; Koch, Wolfgang
Abstract
2014Reliable single cell array CGH for clinical samples
Czyz, Zbigniew T.; Hoffmann, Martin; Schlimok, Günter; Polzer, Bernhard; Klein, Christoph A.
Zeitschriftenaufsatz
2014Reprogramming of COPD lung fibroblasts through formation of induced pluripotent stem cells (iPSCs)
Basma, H.; Gunji, Y.; Iwasawa, S.; Nelson, A.; Farid, M.; Ikari, J.; Liu, X.; Wang, X.; Michalski, J.; Smith, L.M.; Iqbal, J.; El Behery, R.; West, W.; Yelamanchili, S.; Rennard, D.; Holz, O.; Mueller, K.-C.; Magnussen, H.; Rabe, K.F.; Castaldi, P.J.; Rennard, S.I.
Zeitschriftenaufsatz
2014Respiratory Animal Models in the Common Marmoset (Callithrix jacchus)
Curths, Christoph; Knauf, Sascha; Kaup, Franz-Josef
Zeitschriftenaufsatz
2014Reversible addition of the OH radical to p-cymene in the gas phase: Multiple adduct formation. Part 2
Alarcon, P.; Bohn, B.; Zetzsch, C.; Rayez, M.T.; Rayez, J.C.
Zeitschriftenaufsatz
2014Rhinovirus infection in human and mouse precision cut lung slices
Rochlitzer, Sabine; Müller, Meike; Sewald, Katherina; Braun, Armin
Abstract
2014Risk mitigation measures: An important aspect of the environmental risk assessment of pharmaceuticals
Liebig, Markus; Floeter, Carolin; Hahn, Thorsten; Koch, Wolfgang; Wenzel, Andrea; Römbke, Jörg
Zeitschriftenaufsatz
2014Route to route extrapolation factors for regulatory risk assessment - a probabilistic approach
Schröder, Katrin; Hoffmann-Dörr, Simone; Mangelsdorf, Inge; Escher, Sylvia
Abstract
2014Safety and efficacy of Pur118 in the ozone challenge model
Holz, Olaf; Biller, Heike; Müller, Meike; Kane, Katie; Rosano, Molly; Hanrahan, John; Hava, David L.; Hohlfeld, Jens Michael
Abstract
2014Senescence and apoptosis block hematopoietic activation of quiescent hematopoietic stem cells with short telomeres
Wang, Jianwei; Lu, Xin; Sakk, Vadim; Klein, Christoph A.; Rudolph, Karl Lenhard
Zeitschriftenaufsatz
2014Sensitivity comparison of fish and daphnia toxicity - evaluation of ecotoxicological testing strategies and chronic fish testing
May, Martin; Drost, W.; Germer, S.; Juffernholz, T.; Hahn, Stefan
Abstract
2014Sensitivity of different generations and developmental stagesin studies on reproductive toxicity
Schulz, Florian; Batke, Monika; Mangelsdorf, Inge; Pohlenz-Michel, Christina; Simetska, Nelly; Lewin, Geertje
Zeitschriftenaufsatz
2014Severe asthma patients on oral corticosteroid therapy as a distinct phenotype: The european U-BIOPRED cohort
Chung, Kian F.; Gibeon, David; Sousa, Ana R.; Corfield, Julie; Shaw, Dominick E.; Fowler, Stephen J.; Fleming, Louise J.; Riley, John; Jeyasingham, Elisabeth; Rowe, Anthony; Fichtner, Klaus; Roberts, Graham; Bakke, Per; Garnier, Christophe von; Horvath, Ildiko; Riccardo, Polosa; Krug, Norbert; Dahlen, Barbaro; Musial, Jacek; Pahus, Laurie; Myles, David; Compton, Chris; Higenbottam, Tim W.; Montuschi, Paolo; Larsson, Lars; Sandstrom, Thomas; Wagers, Scott S.; Howarth, Peter H.; Bel, Elisabeth; Bansal, Aruna T.; Djukanovic, Ratko; Sterk, Peter J.
Abstract
2014The SILICOAT project: In vitro and in vivo toxicity screening of quartz varieties from traditional ceramics industry and approaches for an effective quartz surface coating
Ziemann, Christina; Reamon-Buettner, Stella Marie; Tillmann, Thomas; Hansen, Tanja; Ibañez, Maria Jesus; Monfort, Eliseo; Bonvicini, Giuliana; Escrig, Alberto; Creutzenberg, Otto H.
Zeitschriftenaufsatz, Konferenzbeitrag
2014Species comparison of interleukin-13 induced airway hyperreactivity in precision-cut lung slices
Danov, Olga; Jiménez Delgado, Sharon Melissa; Drake, Helena; Schindler, Susann; Pfennig, Olaf; Förster, Christine; Braun, Armin; Sewald, Katherina
Zeitschriftenaufsatz, Konferenzbeitrag
2014Toxic effects of various modifications of a nanoparticle following inhalation
Creutzenberg, Otto; Voss, Jens-Uwe; Mangelsdorf, Inge; Tillmann, Thomas; Pohlmann, Gerhard; Hansen, Tanja; Kock, Heiko; Schaudien, Dirk
Zeitschriftenaufsatz, Konferenzbeitrag
2014Toxicity testing of sildenafil base-loaded liposomes in in vitro and ex vivo models for pulmonary application
Paranjpe, Mukta; Neuhaus, Vanessa; Braun, Armin; Müller-Goymann, Christel C.
Zeitschriftenaufsatz
2014Toxicogenomics directory of chemically exposed human hepatocytes
Grinberg, Marianna; Stöber, Regina M.; Edlund, Karolina; Rempel, Eugen; Godoy, Patricio; Reif, Raymond; Widera, Agata; Madjar, Katrin; Schmidt-Heck, Wolfgang; Marchan, Rosemarie; Sachinidis, Agapios; Spitkovsky, Dimitry; Hescheler, Jürgen; Carmo, Helena; Arbo, Marcelo D.; Water, Bob van de; Wink, Steven; Vinken, Mathieu; Rogiers, Vera; Escher, Sylvia; Hardy, Barry; Mitic, Dragana; Myatt, Glenn; Waldmann, Tanja; Mardinoglu, Adil; Damm, Georg; Seehofer, Daniel; Nüssler, Andreas; Weiss, Thomas S.; Oberemm, Axel; Lampen, Alfons; Schaap, Mirjam M.; Luijten, Mirjam; Steeg, Harry van; Thasler, Wolfgang E.; Kleinjans, Jos C.S.; Stierum, Rob H.; Leist, Marcel; Rahnenführer, Jürgen; Hengstler, Jan G.
Zeitschriftenaufsatz
2014Toxicological databases: Modern tools to reduce, refine and replace animal testing
Schröder, Katrin; Simetska, Nelly; Escher, Sylvia; Mangelsdorf, Inge
Zeitschriftenaufsatz, Konferenzbeitrag
2014Toxikologische Untersuchungen von Multiwalled Carbon Nanotubes, mit und ohne Eisenkatalysator, für den Einsatz in der targeted Drug Delivery, durchgeführt an humanen Lungenepithelzellen und Hepatozyten
Requardt, Hendrik
: Eisenbarth, Eva (Erstprüferin); Hennes, Kilian (Zweitprüfer); Dasenbrock, Clemens (Betreuer); Hansen, Tanja (Betreuerin)
Master Thesis
2014TTC: A new concept for inhalation exposure
Tluczkiewicz, Inga; Batke, Monika; Kühne, Ralph; Schüürmann, Gerrit; Mangelsdorf, Inge; Escher, Sylvia
Zeitschriftenaufsatz, Konferenzbeitrag
2014TTC: A new concept for inhalation exposure
Escher, Sylvia; Tluczkiewicz, Inga; Batke, Monika; Kühne, Ralf; Ebert, Ralf-Uwe; Schüürmann, Gerrit; Mangelsdorf, Inge
Abstract
2014Untersuchung der CYP450 Expression in primären humanen Hepatozyten und Hepatozyten-ähnlichen Zellsystemen
Heiermann, Steffen
: Pfitzner, Reinhard (Erstprüfer); Niehof, Monika (Zweitprüfer)
Bachelor Thesis
2014Untersuchungen zum Wirkmechanismus von nanostrukturiertem Carbon Black mit unterschiedlicher Oberflächenbeschaffenheit
Tautenhahn, Sven
: Scharfenberg, Klaus (1. Gutachter); Hansen, Tanja (2. Gutachter); Niehof, Monika (Wiss. Betreuung)
Bachelor Thesis
2014Untersuchungen zur Emission organischer Verbindungen in der Kabinenluft nach dem Enteisen von Verkehrsflugzeugen
Rosenberger, Wolfgang; Wrbitzky, Renate; Elend, Manfred; Schuchardt, Sven
Zeitschriftenaufsatz
2014Use of rat precision-cut lung slices for long-term functional evaluation
Neuhaus, Vanessa; Braun, Armin; Sewald, Katherina
Abstract
2014Validation requirements for alternative methods in inhalation toxicology - case study of a German two phase prevalidation project
Liebsch, M.; Pirow, R.; Smirnova, L.; Tharmann, J.; Linsel, G.; Troeller, S.; Huettig, N.; Bauer, M.; Graebsch, C.; Berger-Preiß, Edith; Kock, Heiko; Oertel, Antje; Ritter, Detlef; Knebel, Jan
Abstract
2014Veränderung von MHC-II positiven Zellen der Atemwegsganglien bei chronischem Hausstaubmilben-Mausmodell und HRV1B Infektion
Funck, Ulrike; Le, Duc Dung; Rochlitzer, Sabine; Heck, Sebastian; Bals, Robert; Braun, Armin; Welte, Tobias; Dinh, Quoc Thai
Abstract
2013Aeroallergen challenge promotes dendritic cell proliferation in the airways
Veres, Tibor Z.; Voedisch, Sabrina; Spies, Emma; Valtonen, Joona; Prenzler, Frauke; Braun, Armin
Zeitschriftenaufsatz
2013Airway region-specific effects of carbon black nanoparticles (CBNP)
Schlick, S.; Kopf, Johannes; Ströbele, M.; Fehrenbach, Heinz
Zeitschriftenaufsatz, Konferenzbeitrag
2013Analysis of the indicative value of repeated dose toxicity studies for reproductive toxicity
Lewin, Geertje; Batke, Monika; Escher, Sylvia; Mangelsdorf, Inge
Zeitschriftenaufsatz, Konferenzbeitrag
2013Animal Studies on the Effect of Nanoparticles in Organs other than the Lungs
Heinrich, U.
Aufsatz in Buch
2013The anti-IL-17A antibody secukinumab does not attenuate ozone-induced airway neutrophilia in healthy volunteers
Kirsten, A.; Watz, H.; Pedersen, F.; Holz, O.; Smith, R.; Bruin, G.; Koehne-Voss, S.; Magnussen, H.; Waltz, D.A.
Zeitschriftenaufsatz
2013Anti-inflammatory and immunomodulatory properties of alpha1-antitrypsin without inhibition of elastase
Jonigk, Danny; Al-Omari, Mariam; Maegel, Lavinia; Müller, Meike; Izykowski, Nicole; Hong, Jaewoo; Hong, Kwangwon; Kim, Soo-Hyun; Dorsch, Martina; Mahadeva, Riva; Laenger, Florian; Kreipe, Hans; Braun, Armin; Shahaf, Galit; Lewis, Eli C.; Welte, Tobias; Dinarello, Charles A.; Janciauskiene, Sabina
Zeitschriftenaufsatz
2013Assessment factors in human health risk assessment and their associated level of safety
Escher, Sylvia; Hoffmann-Doerr, S.; Batke, Monika; Mangelsdorf, Inge
Zeitschriftenaufsatz, Konferenzbeitrag
2013Assessment of immunotoxicity using precision-cut tissue slices
Sewald, Katherina; Braun, Armin
Zeitschriftenaufsatz
2013Associated factors with persistent airflow limitation in asthma in U-BIOPRED
Wagener, A.H.; Gibeon, D.; Yang, X.; Sousa, A.R.; Corfield, J.; Shaw, D.E.; Fowler, S.; Flemming, L.J.; Riley, J.; Jeyasingham, E.; Rowe, A.; Fichtner, K.; Robberts, G.; Bakke, P.; Singer, T.; Geiser, T.; Frey, U.; Horvarth, I.; Polosa, R.; Bonnelykke, K.; Krug, Norbert; Middelveld, R.; Dahlen, S.-E.; Dahlen, B.; Hedlin, G.; Hashimoto, S.; Nordlund, B.; Musial, J.; Woodcock, A.; Murray, C.S.; Pahus, L.; Chanez, P.; Myles, D.; Compton, C.; Higenbottam, T.W.; Montuschi, P.; Vestbo, J.; Larsson, L.; Sandstrom, T.; Bisgaard, H.; Wagers, S.S.; Howarth, P.H.; Bel, E.H.; Djukanovic, R.; Chung, K.F.; Sterk, P.J.
Zeitschriftenaufsatz, Konferenzbeitrag
2013Biokinetics of nanoscaled europium oxide particles following an acute inhalation in rats
Creuzenberg, Otto; Kock, Heiko; Schaudien, Dirk
Zeitschriftenaufsatz, Konferenzbeitrag
2013Biologische Wirkungen von nanostrukturiertem Carbon Black auf pulmonale Zielzellen
Kopf, Johannes Claudius
: Steinberg, Pablo (1. Gutachter); Bicker, Gerd (2. Gutachter); Dasenbrock, Clemens (Wiss. Betreuer)
Dissertation
2013CarbonBlack: A joint research project to establish a test system for predicting human-toxicological effects of synthetic carbon black nanoparticles
Fehrenbach, Heinz; Müller, B.; König, P.; Hansen, Tanja; Bockhorn, H.
Zeitschriftenaufsatz, Konferenzbeitrag
2013Classic examples in toxicologic pathology. CD-ROM
: Karbe, Eberhard (Ed.); Drommer, Wolfgang (Ed.); Germann, Paul-Georg (Ed.); Morawietz, Gerd (Ed.); Kellner, Rupert (Ed.)
Tagungsband
2013Comparative investigations in order to characterise ultrafine particles in fumes in the case of welding and allied processes
Pohlmann, G.; Holzinger, Karl; Spiegel-Ciobanu, V.E.
Zeitschriftenaufsatz
2013Comparison of the pharmacokinetics and pharmacodynamics of once daily tiotropium Respimat® and tiotropium HandiHaler® in COPD patients
Sharma, Ashish; Hohlfeld, Jens; Cornelissen, Piet; Noord, Jan van; Derom, Eric; Towse, Lesley; Peterkin, Vicky; Disse, Bernd
Zeitschriftenaufsatz, Konferenzbeitrag
2013Compatibility in the ustilago maydis-maize interaction requires inhibition of host cysteine proteases by the fungal effector Pit2
Mueller, A.N.; Ziemann, S.; Treitschke, S.; Aßmann, D.; Doehlemann, G.
Zeitschriftenaufsatz
2013Crucial role of transient receptor potential ankyrin 1 and mast cells in induction of nonallergic airway hyperreactivity in mice
Hox, Valérie; Vanoirbeek, Jeron A.; Alpizar, Yeranddy Aguiar; Voedisch, Sabrina; Callebaut, Ina; Bobic, Sonja; Sharify, Ali; Vooght, Vanessa de; Gerven, Laura van; Devos, Fien; Liston, Adrian; Voets, Thomas; Vennekens, Rudi; Bullens, Dominique M.A.; Vries, Annick de; Hoet, Peter; Braun, Armin; Ceuppens, Jan L.; Talavera, Karel; Nemery, Benoit; Hellings, Peter W.
Zeitschriftenaufsatz
2013Cytochrome P450 monooxygenases expression in human epithelial lung cell lines
Niehof, Monika; Hansen, Tanja
Zeitschriftenaufsatz, Konferenzbeitrag
2013A decisive role for B cells in priming of allergy and tolerance by preconceptional immunization of the mother
Happle, Christine; Henning, Christian; Skuljec, Jelena; Hoymann, Gerd; Meyer-Bahlburg, Almut; Hansen, Gesine
Zeitschriftenaufsatz, Konferenzbeitrag
2013Determination of genotoxicity by the Comet assay applied to murine precision-cut lung slices
Switalla, Simone; Knebel, Jan; Ritter, Detlef; Dasenbrock, Clemens; Krug, Norbert; Braun, Armin; Sewald, Katherina
Zeitschriftenaufsatz
2013Developing an upstream process for a monoclonal antibody including medium optimization
Duvar, Sevim; Hecht, Volker; Finger, Juliane; Matthias, Gullans; Ziehr, Holger
Zeitschriftenaufsatz, Konferenzbeitrag
2013Development of a database on toxic effects of nano-objects
Schröder, Katrin; Pohlenz-Michel, Christina; Voß, Jens-Uwe; Simetska, Nelly; Escher, Sylvia; Mangelsdorf, Inge
Zeitschriftenaufsatz, Konferenzbeitrag
2013The devtox project: A comprehensive source of information on developmental abnormalities
Buschmann, Jochen; Chahoud, Ibrahim; Kellner, Rupert; Solecki, Roland
Zeitschriftenaufsatz, Konferenzbeitrag
2013Distribution and morphology of Clara cells in common marmosets (Callithrix jacchus)
Seidel, V.; Hoffmann, R.; Braun, A.; Seehase, S.; Knauf, S.; Kaup, F.-J.; Bleyer, M.
Zeitschriftenaufsatz
2013Effects of carbon black nanoparticles on human pulmonary cell lines and precision cut lung slices
Hansen, Tanja; Kopf, Johannes Claudius; Danov, Olga; Ströbele, M.; Braun, Armin; Sewald, Katherina; Steinberg, P.; Fehrenbach, H.
Zeitschriftenaufsatz, Konferenzbeitrag
2013Effects of dipeptidyl peptidase-4 inhibition in an animal model of experimental asthma: A matter of dose, route, and time
Stephan, Michael; Suhling, Hendrik; Schade, Jutta; Wittlake, Mareike; Tasic, Tihana; Klemann, Christian; Pabst, Reinhard; Jurawitz, Marie-Charlot; Raber, Kerstin A.; Hoymann, Heinz G.; Braun, Armin; Glaab, Thomas; Hoffmann, Torsten; Schmiedl, Andreas; Hoersten, S. von
Zeitschriftenaufsatz
2013Erstellung eines Informationsportals zum Thema: "Validierung GxP-relevanter computergestützter Systeme"
Helberg, Annabelle
: Fortwengel, Gerhard (Erstprüfer); Heina, Martina (Zweitprüfer)
Bachelor Thesis
2013Evaluation of immunohistochemical markers to detect the genotoxic mode of action of fine and ultrafine dusts in rat lungs
Rittinghausen, Susanne; Bellmann, Bernd; Creutzenberg, Otto; Ernst, Heinrich; Kolling, Angelika; Mangelsdorf, Inge; Kellner, Rupert; Beneke, Sascha; Ziemann, Christina
Zeitschriftenaufsatz
2013Evaluation of the gentoxic potential of different radiofrequency electromagnetic fields in MRC-5 cells and B6C3F1 mice
Ziemann, Christina; Tillmann, Thomas; Oertel, Antje; Brockmeyer, Heidrun; Murbach, M.; Capstick, M.; Kuster, N.; Dasenbrock, Clemens
Zeitschriftenaufsatz, Konferenzbeitrag
2013Evaluation of two sampling methods for the determination of gas oil mist and vapour in workplace air
Urbanus, Jan; Berger-Preiß, Edith; Elend, Manfred; Koch, Wolfgang
Abstract
2013Expression of VPAC1 in a murine model of allergic asthma
Lauenstein, Hans D.; Quarcoo, David; Welte, Tobias; Braun, Armin; Groneberg, David A.
Zeitschriftenaufsatz
2013Fast escape of hydrogen from gas cavities around corroding magnesium implants
Kuhlmann, Julia; Bartsch, Yvonne; Willbold, Elmar; Schuchardt, Sven; Holz, Olaf; Hort, Norbert; Höche, Daniel; Heineman, William R.; Witte, Frank
Zeitschriftenaufsatz
2013FeDTex database - a versatile tool condensing data from developmental and reproductive toxicity studies
Schulz, Florian; Batke, Monika; Lewin, Geertje; Escher, Sylvia; Mangelsdorf, Inge
Zeitschriftenaufsatz, Konferenzbeitrag
2013Fraunhofer-Institut für Toxikologie und Experimentelle Medizin. Leistungen und Ergebnisse. Jahresbericht 2012
: Nastevska, Cathrin (Red.); Schlemminger, Karin (Übers.)
Jahresbericht
2013Functional testing of an inhalable nanoparticle based influenza vaccine using a human precision cut lung slice technique
Neuhaus, Vanessa; Schwarz, Katharina; Klee, Anna; Seehase, Sophie; Förster, Christine; Pfennig, Olaf; Jonigk, Danny; Fieguth, Hans-Gerd; Koch, Wolfgang; Warnecke, Gregor; Yusibov, Vidadi; Sewald, Katherina; Braun, Armin
Zeitschriftenaufsatz
2013Harmonization of description and classification of fetal observations: Achievements and problems still unresolved
Solecki, Roland; Barbellion, Stephane; Bergmann, Grigitte; Bürgin, Heinrich; Buschmann, Jochen; Clark, Ruth; Comotto, Laura; Fuchs, Antje; Faqi, Ali Said; Gerspach, Ralph; Grote, Konstanze; Hakansson, Helen; Heinrich, Verena; Heinrich-Hirsch, Barbara; Hofmann, Thomas; Hübel, Ulrich; Inazaki, Thelma Helena; Khalil, Samia; Knudsen, Thomas B.; Kudicke, Sabine; Lingk, Wolfgang; Makris, Susan; Müller, Simone; Paumgartten, Francisco; Pfeil, Rudolf; Rama, Elkiane Macedo; Schneider, Steffen; Shiota, Kohei; Tamborini, Eva; Tegelenbosch, Mariska; Ulbrich, Beate; Duijnhoven, E.A.J. van; Wise, David; Chahoud, Ibrahim
Zeitschriftenaufsatz, Konferenzbeitrag
2013Histone deacetylase inhibitors up-regulate LL-37 expression independent of toll-like receptor mediated signalling in airway epithelial cells
Liu, Q.; Liu, J.; Roschmann, K.I.L.; Egmond, D. van; Golebski, K.; Fokkens, W.J.; Wang, D.; Drunen, C.M. van
Zeitschriftenaufsatz
2013Human peritoneal mesothelial LP9 cells as a model system to determine the toxic and genotoxic potential of multiwalled carbon nanotubes (MWCNTs)
Reamon-Büttner, Stella Marie; Hackbarth, Anja; Voepel, Ines Rebeca; Brockmeyer, Heidrun; Bellmann, Bernd; Ziemann, Christina
Zeitschriftenaufsatz, Konferenzbeitrag
2013Human pleural mesothelial MeT-5A cells are a limited in vitro model for detection of potential asbestos-like genotoxic effects of multiwall carbon nanotubes
Ziemann, Christina; Reamon-Büttner, Stella Marie; Hackbarth, Anja; Brockmeyer, Heidrun; Rahmer, Hartmut; Bellmann, Bernd
Zeitschriftenaufsatz, Konferenzbeitrag
2013IL-13-induced cytokine release and hyperresponsiveness in precision cut lung slices of different species - characterization of a model potentially suitable for translational research of asthma cellular events
Jiménez Delgado, Sharon Melissa; Danov, Olga; Braun, Armin; Pfenning, Olaf; Förster, Christine; Hohlbaum, Andreas; Audoly, Laurent; Hohlfeld, Jens; Sewald, Katherina
Zeitschriftenaufsatz, Konferenzbeitrag
2013IL-13-induced inflammation and hyperreagibility in precision-cut lung slices of different species
Jiménez Delgado, Sharon Melissa
: Braun, Armin (Supervisor); Schuberth, Hans-Joachim (Supervisor)
Master Thesis
2013Improving the diagnosis and management of neuroendocrine tumors
Giandomenico, V.; Modlin, I.M.; Ponten, F.; Nilsson, M.; Landegrend, U.; Bergqvist, J.; Khan, M.S.; Millar, R.P.; Langström, B.; Borlak, J.; Eriksson, B.; Nielsen, B.; Baltzer, L.; Waterton, J.C.; Ahlström, H.; Öberg, K.
Zeitschriftenaufsatz
2013In vitro and ex vivo toxicity screening for predicting toxicological effects of synthetic carbon black nanoparticles in humans
Hansen, Tanja; Kopf, Johannes; Danov, Olga; Ströbele, Michael; Braun, Armin; Sewald, Katherina; Bockhorn, H.; Fehrenbach, Heinz
Zeitschriftenaufsatz, Konferenzbeitrag
2013In vitro and ex vivo toxicological testing of sildenafil-loaded solid lipid nanoparticles
Paranjpe, M.; Neuhaus, V.; Finke, J.H.; Richter, C.; Gothsch, T.; Kwade, A.; Büttgenbach, S.; Braun, A.; Müller-Goymann, C.C.
Zeitschriftenaufsatz
2013Indoor biocide concentrations after application of biocidal aerosol sprays
Berger-Preiß, Edith; Gerling, Susanne; Kock, Heiko; Koch, Wolfgang
Abstract
2013Interspecies extrapolation based on the RepDose database
Escher, S.E.; Batke, M.; Hoffmann-Doerr, S.; Messinger, H.; Mangelsdorf, I.
Zeitschriftenaufsatz
2013Invasive lung function measurement in common marmosets (Callithrix jacchus)
Wichmann, Judi; Curths, Christoph; Dunker, Sarah; Windt, Horst; Hoymann, Heinz Gerd; Lauenstein, Hans Dieter; Becker, Tamara; Kaup, Franz-Josef; Braun, Armin; Knauf, Sascha
Zeitschriftenaufsatz, Konferenzbeitrag
2013The isolated perfused lung (IPL) as a screening tool for aerosol products
Fischer, Monika; Dasenbrock, Clemens; Koch, Wolfgang
Zeitschriftenaufsatz, Konferenzbeitrag
2013Low-dose endotoxin inhalation in healthy volunteers - a challenge model for early clinical drug development
Janssen, Ole; Schaumann, Frank; Holz, Olaf; Lavae-Mokhtari, Bianca; Welker, Lutz; Winkler, Carla; Biller, Heike; Krug, Norbert; Hohlfeld, Jens M.
Zeitschriftenaufsatz
2013Lung alterations following single or multiple low-dose carbon black nanoparticle aspirations in mice
Schreiber, N.; Ströbele, M.; Kopf, J.; Hochscheid, R.; Kotte, E.; Weber, P.; Hansen, T.; Bockhorn, H.; Müller, B.
Zeitschriftenaufsatz
2013Metastasis awakening: The challenges of targeting minimal residual cancer
Polzer, Bernhard; Klein, Christoph A.
Zeitschriftenaufsatz
2013Microbial volatile organic compounds in moldy interiors
Schuchardt, Sven; Strube, Andrea
Zeitschriftenaufsatz
2013Miniaturized drug delivery system TUDOS with accurate metering of microliter volumes
Richter, M.; Wackerle, M.; Kibler, S.; Biehl, M.; Koch, T.; Müller, C.; Halter, Roman; Nuffer, J.; Zeiter, O.
Konferenzbeitrag
2013Minor role of neutrophils in Th17 mediated airway collateral priming towards new antigens
Albrecht, M.; Preston-Hurlburt, P.; Hoymann, Heinz-Gerd; Dittrich, A.
Zeitschriftenaufsatz, Konferenzbeitrag
2013Molecular profiling of single Sca-1(+)/CD34(+,-) cells - the putative murine lung stem cells
Hittinger, Markus; Czyz, Zbigniew T.; Huesemann, Yves; Maneck, Matthias; Botteron, Cathrine; Kaeufl, Stephanie; Klein, Christoph A.; Polzer, Bernhard
Zeitschriftenaufsatz
2013Multiwall carbon nanotubes exhibit a cytotoxic but not directly DNA-damaging potential in human LP9/TERT-1 peritoneal mesothelial cells
Hackbarth, Anja; Ziemann, Christina; Albrecht, L.; Steinberg, Pablo; Bellmann, Bernd
Zeitschriftenaufsatz, Konferenzbeitrag
2013New strategies for the generation of chemical categories under REACH
Batke, Monika; Gundert-Remy, U.; Helma, C.; Kramer, S.; Kleppe-Nordqvist, Sara; Maunz, A.; Partosch, F.; Seeland, M.; Bitsch, Annette
Zeitschriftenaufsatz, Konferenzbeitrag
2013No direct genotoxic potential of different radiofrequency electromagnetic fields in MRC-5 cells and B6C3F1 mice
Dasenbrock, Clemens; Tillmann, Thomas; Oertel, Antje; Brockmeyer, Heidrun; Murbach, M.; Capstick, M.; Kuster, N.; Ziemann, Christina
Zeitschriftenaufsatz, Konferenzbeitrag
2013A novel continuous powder aerosolizer (CPA) for inhalative administration of highly concentrated recombinant surfactant protein-C (rSP-C) surfactant to preterm neonates
Pohlmann, Gerhard; Iwatschenko, P.; Koch, Wolfgang; Windt, Horst; Rast, M.; Gama de Abreu, M.; Taut, F.J.H.; Muynck, C. de
Zeitschriftenaufsatz
2013The OECD guidelines for the testing of chemicals and pesticides
Buschmann, Jochen
Aufsatz in Buch
2013Oncostatin M modulates fibroblast function via signal transducers and activators of transcription proteins-3
Nagahama, K.Y.; Togo, S.; Holz, O.; Magnussen, H.; Liu, X.; Seyama, K.; Takahashi, K.; Rennard, S.I.
Zeitschriftenaufsatz
2013The OSIRIS weight of evidence approach: ITS for the endpoints repeated-dose toxicity (RepDose ITS)
Tluczkiewicz, Inga; Batke, Monika; Kroese, Dinant; Buist, Harrie; Aldenberg, Tom; Pauné, Eduard; Grimm, Helvi; Kühne, Ralph; Schüürmann, Gerrit; Mangelsdorf, Inge; Escher, Sylvia E.
Zeitschriftenaufsatz
2013The OSIRIS weight of evidence approach: ITS mutagenicity and ITS carcinogenicity
Buist, Harrie; Aldenberg, Tom; Batke, Monika; Escher, Sylvia; Klein, Entink R.; Kühne, Ralph; Marquart, Hans; Pauné, Eduard; Rorije, Emiel; Schüürmann, Gerrit; Kroese, Dinant
Zeitschriftenaufsatz
2013OSIRIS, a quest for proof of principle for integrated testing strategies of chemicals for four human health endpoints
Vermeire, Theo; Aldenberg, Tom; Buist, Harrie; Escher, Sylvia; Mangelsdorf, Inge; Pauné, Eduard; Rorije, Emiel; Kroese, Dinant
Zeitschriftenaufsatz
2013Performance testing of a novel Continuous Powder Aerosolizer (CPA) for inhalative administration of surfactant to preterm neonates
Helwich, O.; Koch, W.; Iwatschenko, P.; Windt, H.; Taut, F.J.H.; Muynck, C. de; Pohlmann, G.
Konferenzbeitrag, Zeitschriftenaufsatz
2013Pre-validation of the ex vivo model precision cut lung slices (PCLuS) for the prediction of respiratory toxicology
Hess, A.; Lauenstein, Lan; Schneider, X.; Vogel, S.; Ma-Hock, L.; Kolle, S.; Martin, C.; Pirow, R.; Steinfath, M.; Liebsch, M.; Landsiedel, R.; Braun, Armin; Sewald, Katherina
Zeitschriftenaufsatz, Konferenzbeitrag
2013Prevalidation of the ex vivo model precision cut lung slices (PCLS) for the prediction of respiratory toxicology
Sewald, Katherina; Lauenstein, Lan; Vogel, S.; Hess, A.; Schneider, X.; Martin, C.; Pirow, R.; Liebsch, M.; Landsiedel, R.; Braun, Armin
Zeitschriftenaufsatz, Konferenzbeitrag
2013Proposal for biomonitoring values according to the extended approach of the HBM commission
Licht, Oliver; Voß, Jens-Uwe; Wahnschaffe, Ulrich; Mangelsdorf, Inge
Zeitschriftenaufsatz, Konferenzbeitrag
2013Pulmonary toxicity of printer toner following inhalation and intratracheal instillation
Morimoto, Yasuo; Oyabu, Takako; Horie, Masanori; Kambara, Tatsunori; Izumi, Hiroto; Kuroda, Etsushi; Creuzenberg, Otto; Bellmann, Bernd; Pohlmann, Gerhard; Schuhardt, Sven; Hansen, Tanja; Ernst, Heinrich
Zeitschriftenaufsatz
2013Pyrethrum and pyrethroid metabolites (after liquid phase extraction) in urine [Biomonitoring Methods, 2013]
Berger-Preiß, Edith; Gerling, Susanne; Leng, G.; Gries, W.
Aufsatz in Buch
2013Regulatorische Anforderungen an Informationen zur dermalen Absorption und deren wirtschaftliche Auswirkungen mit besonderem Fokus auf der Biozid-Zulassung
Scholz, Roland
: Bitsch, Annette (1. Betreuer); Hahn, Stefan (2. Betreuer); Lüning, Ulrich (1. Gutachter); Maser, Edmund (2. Gutachter)
Master Thesis
2013Rekrutierung von Teilnehmern für klinische Studien mit modernen Medien
Boos, Julia
: Fortwengel, Gerhard (Erstprüfer); Sostak, Nadine (Zweitprüfer)
Bachelor Thesis
2013Relative oral bioavailability of 3-MCPD from 3-MCPD fatty acid esters in rats
Abraham, K.; Appel, K.E.; Berger-Preiß, E.; Apel, E.; Gerling, S.; Mielke, H.; Creutzenberg, O.; Lampen, A.
Zeitschriftenaufsatz
2013Relative oral bioavailability of glycidol from glycidyl fatty acid esters in rats
Appel, Klaus E.; Abraham, Klaus; Berger-Preiss, Edith; Hansen, Tanja; Apel, Elisabeth; Schuchardt, Sven; Vogt, Carla; Bakhiya, Nadiya; Creutzenberg, Otto; Lampen, Alfonso
Zeitschriftenaufsatz
2013Relevance of non-guideline studies for risk assessment. The coverage model based on most frequent targets in repeated dose toxicity studies
Batke, Monika; Aldenberg, Tom; Escher, Sylvia; Mangelsdorf, Inge
Zeitschriftenaufsatz
2013Reply to the "Letter to the Editor" by Morfeld et al. "Particle diameter estimates of Creutzenberg et al. (2012) are distorted due to the slicing bias of transmission electron microscopy"
Creutzenberg, O.H.; Bellmann, B.; Korolewitz, R.; Koch, W.; Mangelsdorf, I.; Tillmann, T.; Schaudien, D.
Zeitschriftenaufsatz
2013Reversible addition of the OH radical to p-cymene in the gas phase: Kinetic analysis assuming formation of a single adduct. Part 1
Alarcón, P.; Strekowski, R.; Zetzsch, C.
Zeitschriftenaufsatz
2013Role of human papillomaviruses in persistent and glucocorticoid-resistant juvenile phimosis
Pilatz, A.; Altinkilic, B.; Rusz, A.; Izykowski, N.; Traenkenschuh, W.; Rische, J.; Lehmann, U.; Herbst, C.; Maegel, L.; Becker, J.; Weidner, W.; Jonigk, D.
Zeitschriftenaufsatz
2013Safety profile and pharmacokinetics of an inhaled GATA-3-specific DNAzyme in a phase Ib study in patients with stable allergic asthma
Hohlfeld, Jens; Lüer, Katrin; Krug, Norbert; Turowska, Agnieszka; Renz, Harald; Garn, Holger; Homburg, Ursula
Zeitschriftenaufsatz, Konferenzbeitrag
2013Sampling and analysis of exhaled breath particles
Schwarz, Katharina; Holz, Olaf; Koch, Wolfgang; Hohlfeld, Jens M.
Konferenzbeitrag, Zeitschriftenaufsatz
2013Selection and adaptation during metastatic cancer progression
Klein, C.A.
Zeitschriftenaufsatz
2013Severity of allergic airway disease due to house dust mite allergen is not increased after clinical recovery of lung infection with chlamydia pneumoniae in mice
Dutow, Pavel; Lingner, Sandra; Laudeley, Robert; Glage, Silke; Hoymann, Heinz-Gerd; Dittrich, Anna-Maria; Fehlhaber, Beate; Müller, Meike; Braun, Armin; Klos, Andreas
Zeitschriftenaufsatz
2013Spontane Nebenwirkungsmeldungen zu Analgetika - Relevanz für Risikobewertung?
Borlak, J.
Zeitschriftenaufsatz
2013Spontaneous neoplastic lesions in control syrian hamsters in 6-, 12-, and 24-month short-term and carcinogenicity studies
McInnes, Elizabeth F.; Ernst, Heinrich; Germann Paul-Georg
Zeitschriftenaufsatz
2013Studies on the mode of action of Multi-Walled Carbon Nanotubes onto human bronchial epithelial cells
Walter, Dorothee; Niehof, Monika; Hackbarth, Anja; Hansen, Tanja
Abstract
2013Surfactant and allergic airway inflammation
Winkler, C.; Hohlfeld, J.M.
Zeitschriftenaufsatz
2013Toxic effects of multiwall carbon nanotubes (MWCNT) in vivo and in vitro
Hackbarth, Anja; Schaudien, Dirk; Bellmann, Bernd; Ernst, Heinrich; Ziemann, Christina; Leonhardt, A.; Heinrich, Uwe; Rittinghausen, Susanne
Zeitschriftenaufsatz, Konferenzbeitrag
2013Toxic effects of MWCNT in vivo and in vitro
Schlichting, Anja; Ziemann, Christina; Leonhardt, A.; Rittinghausen, Susanne; Schaudien, Dirk; Bellmann, Bernd
Zeitschriftenaufsatz, Konferenzbeitrag
2013Toxicity profile of the GATA-3-specific DNAzyme hgd40 after inhalation exposure
Fuhst, R.; Runge, F.; Buschmann, J.; Ernst, H.; Praechter, C.; Hansen, T.; Erichsen, J. von; Turowska, A.; Hoymann, H.-G.; Müller, M.; Pohlmann, G.; Sewald, K.; Ziemann, C.; Schlüter, G.; Garn, H.
Zeitschriftenaufsatz
2013Transcriptional defect of an inherited NKX2-5 haplotype comprising a SNP, a nonsynonymous and a synonymous mutation, associated with human congenital heart disease
Reamon-Büttner, Stella Marie; Sattleger, Evelyn; Ciribilli, Yari; Inga, Alberto; Wessel, Armin; Borlak, Jürgen
Zeitschriftenaufsatz
2013A translational non-human primate model for human asthma in the common marmoset (Callithrix Jacchus)
Curths, Christoph; Wichmann, Judy; Becker, Tamara; Kaup, Franz-Josef; Hohlfeld, Jens M.; Sewald, Katherina; Windt, Horst; Dunker, Sarah; Braun, Armin; Knauf, Sascha
Zeitschriftenaufsatz, Konferenzbeitrag
2013Ein translationales LPS-Modell zur präklinischen Testung anti-inflammatorischer Substanzen im Weißbüschelaffen (Callithrix jacchus)
Seehase, Sophie; Switalla, Simone; Neuhaus, Vanessa; Zöller, Martina; Kaup, Franz Josef; Schlumbohm, Christina; Fuchs, E.; Lauenstein, Hans Dieter; Sewald, Katherina; Hohlfeld, Jens M.; Braun, Armin; Knauf, Sascha
Zeitschriftenaufsatz, Konferenzbeitrag
2013Ein translationales Tiermodel für das allergische Asthma des Menschen im Weißbüschelaffen (Callithrix jacchus)
Curths, Christoph; Braun, Armin; Knauf, Sascha
Zeitschriftenaufsatz, Konferenzbeitrag
2013Ein translationales Tiermodell für das allergische Asthma des Menschen im Weißbüschelaffen (Callithrix jacchus)
Curths, Christoph; Becker, T.; Kaup, Franz Josef; Schlumbohm, Christina; Sewald, Katherina; Hohlfeld, Jens M.; Dunker, Sarah; Braun, Armin; Knauf, Sascha
Zeitschriftenaufsatz, Konferenzbeitrag
2013U-BIOPRED asthma cohort: Inflammatory markers and corticosteroid use
Gibeon, D.; Wagener, A.H.; Yang, X.; Sousa, A.R.; Corfield, J.; Shaw, D.E.; Fowler, S.; Flemming, L.J.; Jeyasingham, E.; Rowe, A.; Fichtner, K.; Robberts, G.; Bakke, P.; Singer, T.; Geiser, T.; Frey, U.; Horvarth, I.; Polosa, R.; Bonnelykke, K.; Krug, Norbert; Middelveld, R.; Dahlen, S.-E.; Dahlen, B.; Hedlin, G.; Hashimoto, S.; Nordlund, B.; Musial, J.; Woodcock, A.; Murray, C.S.; Pahus, L.; Myles, D.; Compton, C.; Higenbottam, T.W.; Montuschi, P.; Vestbo, J.; Larsson, L.; Sandstrom, T.; Bisgaard, H.; Wagers, S.S.; Howarth, P.H.; Bel, E.H.; Djukanovic, R.; Sterk, P.J.; Chung, K.F.
Zeitschriftenaufsatz, Konferenzbeitrag
2013Unexpected brain lesions in lactating Sprague-Dawley rats in a two-generation inhalation reproductive toxicity study with pentafluoropropane (HFC-245fa)
Buschmann, J.; Fuhst, R.; Tillmann, T.; Ernst, H.; Kolling, A.; Pohlmann, G.; Preiß, A.; Berger-Preiß, E.; Hansen, T.; Kellner, R.; Rusch, G.M.
Zeitschriftenaufsatz
2013Untersuchungen zum Wirkmechanismus von Multi-Walled Carbon Nanotubes an Bronchialepithelzellen
Walter, Dorothee
: Steinberg, Pablo (Erstprüfer); Hansen, Tanja (Zweitprüfer); Niehof, Monika (Betreuer)
Master Thesis
2013Use of biocides - toxicological effects versus microbiological efficacy
Zwintscher, Ariane; Bitsch, Annette
Zeitschriftenaufsatz, Konferenzbeitrag
2013Vacuolation and mineralisation as dominant age-related findings in hamster brains
Gerhauser, I.; Wohlsein, P.; Ernst, H.; Germann, P.-G.; Baumgärtner, W.
Zeitschriftenaufsatz
2013Zur Entstehung, Charakterisierung und diagnostischen Nutzbarkeit in der menschlichen Lunge endogen generierter exhalierter Aerosole
Schwarz, Katharina
: Turek, Thomas (Vorsitzender); Koch, Wolfgang (Erstprüfer); Weber, Alfred (Zweitprüfer)
Dissertation
2012Acute cigarette smoke exposure induces cytotoxicity and inflammation in living tissue of precision-cut lung slices
Lauenstein, Lan; Switalla, Simone; Ritter, Detlef; Knebel, Jan; Dasenbrock, Clemens; Braun, Armin; Sewald, Katherina
Abstract
2012Acute ozone induced airway inflammation does not effect resting human sympathetic nerve traffic
Tank, J.; Biller, Heike; Heusser, K.; Holz, Olaf; Diedrich, A.; Framke, T.; Koch, A.; Grosshennig, A.; Koch, Wolfgang; Krug, Norbert; Jordan, J.; Hohlfeld, Jens
Zeitschriftenaufsatz, Konferenzbeitrag
2012Allergic airway inflammation in mice deficient for the antigen-processing protease cathepsin E
Pilzner, C.; Bühling, F.; Reinheckel, T.; Chwieralski, C.; Rathinasamy, A.; Lauenstein, H.-D.; Wex, T.; Welte, T.; Braun, A.; Groneberg, D.A.
Zeitschriftenaufsatz
2012Alternative activation of macrophages during the allergic airway inflammation alters antigen presenting capacities
Winkler, Carla; Carstens, Hauke; Müller, Meike; Schaumann, Frank; Faulenbach, Cornelia; Hohlfeld, Jens M.
Abstract
2012Anforderungsanalyse und Auswahl einer Software zur Intranetpräsentation eines Leitfadendokuments
Kleine, Maren
: Bott, Oliver (Erstprüfer); Heina, Martina (Zweitprüfer)
Bachelor Thesis
2012Assessment of lung toxicity induced by chemical allergens in human precision-cut lung slices
Lauenstein, Lan; Switalla, Simone; Prenzler, Frauke; Pfennig, Olaf; Förster, Christine; Braun, Armin; Sewald, Katherina
Abstract
2012Attenuation of inhibitory prostaglandin E2 signaling in human lung fibroblasts is mediated by phosphodiesterase 4
Michalski, Joel; Kanaji, Nobuhiro; Liu, Xiangde; Nogel, Steve; Wang, Xingqui; Basma, Hesham; Nakanishi, Masanori; Sato, Tadasi; Gunji, Yoko; Fahrid, Maha; Nelson, Amy; Muller, Kai-Christian; Holz, Olaf; Magnussen, Helgo; Rabe, Klaus F.; Toews, Myron L.; Rennard, Stephen I.
Zeitschriftenaufsatz
2012Bacillus Anthracis lethal toxin impairs alveolar epithelial barrier function
Langer, M.; Booth, J.; Duggan, E.S.; Patel, V.I.; Awasthi, S.; Metcalf, J.; Veres, T.Z.; Prenzler, F.; Sewald, K.; Braun, A.; Lupu, F.; Coggeshall, K.
Konferenzbeitrag, Zeitschriftenaufsatz
2012Bacillus anthracis lethal toxin reduces human alveolar epithelial barrier function
Langer, Marybeth; Duggan, Elizabeth S.; Booth, John L.; Patel, Vineet I.; Zander, Ryan A.; Silasi-Mansat, Robert; Ramani, Vijay; Veres, Tibor Z.; Prenzler, Frauke; Sewald, Katherina; Williams, Daniel M.; Coggeshall, Kenneth M.; Awasthi, Shanjana; Lupu, Florea; Burian, Dennis; Ballard, Jimmy D.; Braun, Armin; Metcalf, Jordan P.
Zeitschriftenaufsatz
2012Bacterial infection triggers exacerbation of established pulmonary fibrosis in mice: Impact on lung protective immunity
Ueberberg, Bianca; Janze, Ann-Kathrin; Steinwede, Kathrin; Maus, Regina; Magel, Lavinia; Hoymann, Heinz-Gerd; Braun, Armin; Langer, Florian; Jonigk, Danny; Kolb, Martin; Gauldie, Jack; Welte, Tobias; Maus, Ulrich A.
Abstract
2012Die Bedeutung von Pollen und Starch Granules bei der Allergie der Atemwege
Emmert, Lorenz Samy
: Krug, Norbert (Doktorvater)
Dissertation
2012Biological interactions and toxicity of nanomaterials in the respiratory tract and various approaches of aerosol generation for toxicity testing
Creutzenberg, Otto H.
Zeitschriftenaufsatz
2012Break-up testing of waste-form materials
Metcalfe, M.P.; Koch, Wolfgang; Turner, G.
Zeitschriftenaufsatz
2012Cathepsin G and neutrophil elastase contribute to lung protective immunity against mycobacterial infections in mice
Steinwede, Kathrin; Maus, Regina; Bohling, Jennifer; Voedisch, Sabrina; Braun, Armin; Ochs, Matthias; Schmiedl, Andreas; Walter, Kerstin; Bange, Franz; Welte, Tobias; Ehlers, Stefan; Maus, Ulrich A.
Abstract
2012Cathepsin G and neutrophil elastase contribute to lung-protective immunity against mycobacterial infections in mice
Steinwede, Kathrin; Maus, Regina; Bohling, Jennifer; Voedisch, Sabrina; Braun, Armin; Ochs, Matthias; Schmiedl, Andreas; Länger, Florian; Gauthier, Francis; Roes, Jürgen; Welte, Tobias; Bange, Franz C.; Niederweis, Michael; Bühling, Frank; Maus, Ulrich A.
Zeitschriftenaufsatz
2012Change in agglomeration status and toxicokinetic fate of various nanoparticles in vivo following lung exposure in rats
Creutzenberg, O.; Bellmann, B.; Korolewitz, R.; Koch, W.; Mangelsdorf, I.; Tillmann, T.; Schaudien, D.
Zeitschriftenaufsatz
2012Characterization of exhaled particles from the human lung in airway obstruction
Biller, Heike; Schwarz, Katharina; Windt, Horst; Koch, Wolfgang; Hohlfeld, Jens M.
Abstract
2012Chlamydia pneumoniae and asthma bronchiale in a mouse model: Decrease in airway hyperresponsiveness to house dust mite allergen after pneumonia
Dutow, P.; Lingner, S.; Bode, J.; Laudeley, R.; Glage, S.; Hoymann, H.G.; Dittrich, A.M.; Muller, M.; Braun, A.; Klos, A.
Konferenzbeitrag, Zeitschriftenaufsatz
2012Combined micro-PET/micro-CT imaging of lung tumours in SPC-raf and SPC-myc transgenic mice
Rodt, T.; Luepke, M.; Boehm, C.; Hueper, K.; Halter, R.; Glage, S.; Hoy, L.; Wacker, F.; Borlak, J.; Falck, C. von
Zeitschriftenaufsatz
2012Comparison of methods to derive health-based guidance or limit values for chemicals
Licht, Oliver; Voss, Jens Uwe; Mangelsdorf, Inge
Zeitschriftenaufsatz, Konferenzbeitrag
2012Comparison of timothy grass pollen extract- and single major allergen-induced gene expression and mediator release in airway epithelial cells
Röschmann, K.I.L.; Kuijen, A.-M. van; Luiten, S.; Jonker, M.J.; Breit, T.M.; Fokkens, W.J.; Petersen, A.; Drunen, C.M. van
Zeitschriftenaufsatz
2012CRTH2 antagonist, BI 671800 (BI), reduces nasal symptoms and inhibits nasal cytokines and eosinophils in SAR patients exposed to grass pollen in an environmental challenge chamber (ECC)
Krug, Norbert; Gupta, A.; Badorrek, Philipp; Müller, Meike; Casper, Anja; Pivovarova, A.; Hilbert, J.; Koenen, R.; Hohlfeld, Jens M.; Wood, C.
Abstract
2012Cytoprotective effect of the small GTPase RhoB expressed upon Ras glucosylation by Clostridium sordellii Lethal Toxin
May, Martin; Huelsenbeck, J.; Schulz, Florian; Fritz, G.; Genth, H.
Zeitschriftenaufsatz, Konferenzbeitrag
2012Depletion of neutrophils from induced sputum using a novel bead and sieve-separation system
Holz, Olaf; Schaumann, Frank; Janben, Ole; Lavae-Mokhtari, Bianca; Witte, Lena; Krug, Norbert; Heinrich, J. M.; Hohlfeld, Jens M.
Abstract
2012Derived values and databases for non-cancer endpoints: Considerations and concerns
Tluczkiewicz, Inga; Batke, Monika; Mangelsdorf, Inge; Escher, Sylvia
Zeitschriftenaufsatz, Konferenzbeitrag
2012Detection of air trapping in chronic obstructive pulmonary disease by low frequency ultrasound
Morenz, Katrin; Biller, Heike; Wolfram, Frank; Leonhardt, Steffen; Ruter, Dirk; Glaab, Thomas; Uhlig, Stefan; Hohlfeld, Jens M.
Zeitschriftenaufsatz
2012Dissecting epigenetic silencing complexity in the mouse lung cancer suppressor gene cadm1
Reamon-Büttner, Stella Marie; Borlak, Jürgen
Zeitschriftenaufsatz
2012Effect of Tiotropium on in vivo and ex vivo lung function in a rat model of bronchoconstriction
Seehase, Sophie; Köhncke, Sarah-Philine; Hoymann, Heinz-Gerd; Braun, Armin; Sewald, Katherina
Abstract
2012Effekte der Partikeltranslokation von feinen und nanoskaligen Titandioxid-Partikeln nach Inhalation und intranasaler Instillation bei der Ratte
Lehmbecker, Annika
: Baumgärtner, Wolfgang (1. Gutachter); Claus, Peter (2. Gutachter); Gernert, Manuela (3. Gutachter); Harleman, Johannes H. (4. Gutachter)
Dissertation
2012Estimation of the consumer inhalation risk of waterproofing sprays
Fischer, Monika; Koch, Wolfgang; Windt, Horst; Dasenbrock, Clemens
Zeitschriftenaufsatz, Konferenzbeitrag
2012Etablierung pathway-spezifischer Genexpressionsanalysen am Beispiel der Wirkung von Paraquat auf humane Lungenepithelzellen
Augustin, Christian
: Pfitzner, Reinhard (Erstprüfer); Niehof, Monika (Zweitprüfer)
Bachelor Thesis
2012The EvA study: Aims and strategy
Ziegler-Heitbrock, L.; Frankenberger, M.; Heimbeck, I.; Burggraf, D.; Wjst, M.; Häussinger, K.; Brightling, C.; Gupta, S.; Parr, D.; Subramanian, D.; Singh, D.; Kolsum, U.; Boschetto, P.; Potena, A.; Gorecka, D.; Nowinski, A.; Barta, I.; Döme, B.; Strausz, J.; Greulich, T.; Vogelmeier, C.; Bals, R.; Hohlfeld, J.M.; Welte, T.; Venge, P.; Gut, I.; Boland, A.; Olaso, R.; Hager, J.; Hiemstra, P.; Rabe, K.F.; Unmüßig, M.; Müller-Quernheim, J.; Prasse, A.
Zeitschriftenaufsatz
2012Ex vivo lung culture models of marmoset monkeys and humans for anti-inflammatory drug testing
Seehase, Sophie; Neuhaus, Vanessa; Kaup, Franz-Josef; Pfennig, O.; Förster, Christine; Hohlfeld, Jens Michael; Knauf, Sascha; Braun, Armin; Sewald, Katherina
Abstract
2012Experience with an allergen challenge chamber for clinical trials in allergic rhinitis
Krug, Norbert; Badorrek, Phillipp; Hohlfeld, Jens Michael
Zeitschriftenaufsatz, Konferenzbeitrag
2012Food for thought... A toxicology ontology roadmap
Hardy, B.; Apic, G.; Carthew, P.; Clark, D.; Cook, D.; Dix, I.; Escher, S.; Hastings, J.; Heard, D.J.; Jeliazkova, N.; Judson, P.; Matis-Mitchell, S.; Mitic, D.; Myatt, G.; Shah, I.; Spjuth, O.; Tcheremenskaia, O.; Toldo, L.; Watson, D.; White, A.; Yang, C.
Zeitschriftenaufsatz
2012Fraunhofer-Institut für Toxikologie und Experimentelle Medizin. Leistungen und Ergebnisse. Jahresbericht 2011
: Nastevska, Cathrin (Red.); Schlemminger, Karin (Übers.)
Jahresbericht
2012Generation of ips-like cells from COPD lung fibroblasts
Basma, Hesham; Gunji, Yoko; Liu, Xiangde; Nelson, Amy; Farid, Maha; Iwasawa, Shunichiro; Ikari, Jun; Wang, Xingqui; Holz, Olaf; Müller, Kai-Christian; Magnussen, Helgo; Rabe, Klaus; Rennard, Stephen I.
Abstract
2012Human alveolar epithelial barrier function is impaired by bacillus anthracis lethal toxin
Langer, Marybeth; Booth, John L.; Patel, Vineet I.; Duggan, Elizabeth S.; Braun, Armin; Ramani, Vijay; Awasthi, Shanjana; Silasi-Mansat, Robert; Lupu, Florea; Coggeshall, Kenneth M.; Metcalf, Jordan P.
Abstract
2012Human pleural mesothelial MeT-5A cells are a limited in vitro model system in determining potential asbestos-like effects of multiwall carbon nanotubes
Ziemann, Christina; Reamon-Büttner, Stella-Marie; Schlichting, Anja; Brockmeyer, Heidrun; Rahmer, Hartmut; Bellmann, Bernd
Zeitschriftenaufsatz, Konferenzbeitrag
2012Immunotoxic characterization of a nanoparticle-based inhalable influenza vaccine in murine and human precision cut lung slices
Neuhaus, Vanessa; Schwarz, Katharina; Koch, Wolfgang; Sewald, Katherina; Yusibov, V.; Braun, Armin
Abstract
2012Impacts after inhalation of nano- and fine-sized titanium dioxide particles: morphological changes, translocation within the rat lung, and evaluation of particle deposition using the relative deposition index
Eydner, M.; Schaudien, D.; Creutzenberg, O.; Ernst, H.; Hansen, T.; Baumgärtner, W.; Rittinghausen, S.
Zeitschriftenaufsatz
2012In vitro study revealed different size behavior of different nanoparticles
Schaudien, D.; Knebel, J.; Creutzenberg, O.
Zeitschriftenaufsatz
2012Inactivation of human white blood cells in platelet concentrates after pathogen reduction by UVC-light in the theraflex UV-platelets system
Seltsam, A.; Pohler, P.; Mueller, M.; Winkler, C.; Muller, T.H.
Konferenzbeitrag, Zeitschriftenaufsatz
2012Influence of extremely low frequency magnetic fields on juvenile development and behaviour in a mouse model
Lewin, Geertje; Buschmann, Jochen; Asmuss, Monika
Zeitschriftenaufsatz, Konferenzbeitrag
2012International harmonization of toxicologic pathology nomenclature
Mann, P.C.; Vahle, J.; Keenan, C.M.; Baker, J.F.; Bradley, A.E.; Goodman, D.G.; Harada, T.; Herbert, R.; Kaufmann, W.; Kellner, R.; Nolte, T.; Rittinghausen, S.; Tanaka, T.
Zeitschriftenaufsatz
2012International round-robin study on the Ames fluctuation test
Reifferscheid, Georg; Maes, Hanna; Allner, Bernhard; Badurova, Jana; Belkin, Shimshon; Bluhm, Kerstin; Brauer, Frank; Bressling, Jana; Domeneghetti, Stefania; Elad, Tal; Flückiger-Isler, Sini; Grummt, Hans-Juergen; Gürtler, Rainer; Hecht, Adiel; Heringa, Minne; Hollert, Henner; Huber, Stefanie; Kramer, Maike; Ratte, Toni; Sauerborn-Klobucar, Roberta; Magdeburg, Axel; Sokolowski, Andrea; Soldan, Premysl; Smital, Tvrtko; Stalter, Daniel; Venier, Paola; Ziemann, Christina; Zipperle, Jürgen; Buchinger, Sebastian
Zeitschriftenaufsatz
2012Kinetics and mechanism of the reaction of OH with the trimethylbenzenes - experimental evidence for the formation of adduct isomers
Bohn, B.; Zetzsch, C.
Zeitschriftenaufsatz
2012Lack of detectable diffuse or neuritic plaques and neurofibrillary tangles in the brains of aged hamsters
Gerhauser, Ingo; Wohlsein, Peter; Ernst, Heinrich; Germann, Paul-Georg; Baumgärtner, Wolfgang
Zeitschriftenaufsatz
2012Leichtbau in Mobilität und Fertigung
: Rommel, Steve (Red.); Geiger, Raphael (Red.); Schneider, Ralph (Red.); Baumann, Michael (Red.); Brandstetter, Peter (Red.); Held, Michael (Red.); Albrecht, Stefan (Red.); Creutzenberg, Otto (Red.); Dasenbrock, Clemens (Red.)
Studie
2012Low-dose endotoxin inhalation in healthy volunteers: A challenge model for early clinical drug development of novel anti-inflammatory compounds
Schaumann, Frank; Holz, Olaf; Janben, Ole; Lavae-Mokhtari, Bianca; Witte, Lena; Biller, Heike; Krug, Norbert; Hohlfeld, Jens M.
Abstract
2012LPS-induced lung inflammation in marmoset monkeys - an acute model for anti-inflammatory drug testing
Seehase, S.; Lauenstein, H.D.; Schlumbohm, C.; Switalla, S.; Neuhaus, V.; Förster, C.; Fieguth, H.G.; Pfennig, O.; Fuchs, E.; Kaup, F.J.; Bleyer, M.; Hohlfeld, J.M.; Braun, A.; Sewald, K.; Knauf, S.
Zeitschriftenaufsatz
2012Lung function measurements in rodents in safety pharmacology studies
Hoymann, Heinz Gerd
Zeitschriftenaufsatz
2012Lung tumour growth kinetics in SPC-c-Raf-1-BB transgenic mice assessed by longitudinal in-vivo micro-CT quantification
Rodt, Thomas; Falck, Christian von; Dettmer, Sabine; Hueper, Katja; Halter, Roman; Hoy, Ludwig; Luepke, Matthias; Borlak, Jürgen; Wacker, Frank
Zeitschriftenaufsatz
2012Marmoset monkeys as a preclinical model in respiratory research
Seehase, Sophie
: Kaup, Franz-Josef (1. Gutachter); Zimmermann, Elke (2. Gutachterin); Braun, Armin (Wiss. Betreuung)
Dissertation
2012Measurement of diameter of different nanoparticle agglomerates after contact with A549 cells revealed different size behavior
Schaudien, Dirk; Knebel, Jan; Rittinghausen, Susanne; Creutzberg, Otto
Zeitschriftenaufsatz, Konferenzbeitrag
2012MicroScout - an assistance system for histological analysis in forensics
Jahn, U. von; Ernst, Heinrich; Matthies, H.K.; Albrecht, U.V.
Konferenzbeitrag, Zeitschriftenaufsatz
2012MYC-regulated genes involved in liver cell dysplasia identified in a transgenic model of liver cancer
Hunecke, D.; Spanel, R.; Langer, F.; Nam, S.W.; Borlak, J.
Zeitschriftenaufsatz
2012Nasal passages of Göttingen minipigs from the neonatal period to young adult
Kuper, C.F.; Ernst, H.; Oostrum, L.C.M. van; Rittinghausen, S.; Penninks, A.H.; Ganderup, N.-C.; Wolterbeek, A.P.M.
Zeitschriftenaufsatz
2012Nephrotoxicity of organic solvents from skin exposure
Mangelsdorf, Inge; Voss, Jens Uwe
Aufsatz in Buch
2012Neurally mediated airway constriction in human and other species
Schlepütz, M.; Rieg, A.D.; Seehase, S.; Spillner, J.; Perez-Bouza, A.; Braunschweig, T.; Schroeder, T.; Bernau, M.; Lambermont, V.; Schlumbohm, C.; Sewald, K.; Autschbach, R.; Braun, A.; Kramer, B.W.; Uhlig, S.; Martin, C.
Zeitschriftenaufsatz
2012Neuro-immune interaction in allergic airway inflammation: Expression and function of dendritic cells in sensory airway ganglia neurons
Le, Dung D.; Rochlitzer, Sabine; Funck, Ulrke; Suhling, Hendrik; Braun, Armin; Welte, Tobias; Din, Quoc Thai
Abstract
2012Neuropeptides control the dynamic behavior of airway mucosal dendritic cells
Voedisch, S.; Rochlitzer, S.; Veres, T.Z.; Spies, E.; Braun, A.
Zeitschriftenaufsatz
2012Neuropeptides influence airway dendritic cell behavior
Braun, Armin; Spies, Emma; Rochlitzer, Sabine; Voedisch, Sabrina
Abstract
2012A new analytical approach for the comprehensive characterization of polar xenobiotic organic compounds downgradient of old municipal solid waste (MSW) landfills
Preiß, A.; Berger-Preiß, E.; Elend, M.; Gerling, S.; Kühn, S.; Schuchardt, S.
Zeitschriftenaufsatz
2012A new model for testing human specific anti-inflammatory drugs: LPS-induced lung inflammation in the common marmoset
Knauf, Sascha; Seehase, Sophie; Switalla, Simone; Neuhaus, Vanessa; Zöller, Martina; Kaup, Franz-Josef; Schlumbohm, Christina; Fuchs, Eberhard; Lauenstein, Hand D.; Sewald, Katherina; Hohlfeld, Jens Michael; Braun, Armin
Abstract
2012The non-intubated, spontaneously breathing, continuous positive airway pressure (CPAP) ventilated pre-term lamb: A unique animal model
Rahmel, D.K.; Pohlmann, G.; Iwatschenko, P.; Volland, J.; Liebisch, S.; Kock, H.; Mecklenburg, L.; Maurer, C.; Kemkowski, J.; Taut, F.J.H.
Zeitschriftenaufsatz, Konferenzbeitrag
2012OpenTox predictive toxicology framework
Tcheremenskaia, Olga; Benigni, Romualdo; Nikolova, Ivelina; Jeliazkova, Nina; Escher, Sylvia E.; Batke, Monika; Baier, Thomas; Poroikov, Vladimir; Lagunin, Alexey; Rautenberg, Micha; Hardy, Barry
Zeitschriftenaufsatz
2012Optimierung der Auswertmethodik zur Quantifizierung von pathologischen Veränderungen durch Carbon Nanotubes
Weiß, Martin
: Kauer, Gerhard (Erstprüfer); Rittinghausen, Susanne (Zweitprüfer)
Bachelor Thesis
2012PET/CT imaging of c-Myc transgenic mice identifies the genotoxic N-Nitroso-Diethylamine as carcinogen in a Short-Term cancer bioassay
Hueper, K.; Elalfy, M.; Laenger, F.; Halter, R.; Rodt, T.; Galanski, M.; Borlak, J.
Zeitschriftenaufsatz
2012A pilot study on the refinement of acute inhalation toxicity studies
Fischer, M.; Koch, W.; Windt, H.; Dasenbrock, C.
Zeitschriftenaufsatz
2012Pollen starch granules in bronchial inflammation
Badorrek, Philipp; Dick, Melanie; Emmert, Lorenz; Schaumann, Frank; Koch, Wolfgang; Hecker, Hartmut; Murdoch, Robert; Hohlfeld, Jens M.; Krug, Norbert
Zeitschriftenaufsatz
2012Prostaglandin E2 stimulates the production of vascular endothelial growth factor through the E-prostanoid-2 receptor in cultured human lung fibroblasts
Nakanishi, Masanori; Sato, Tadashi; Li, Yingji; Nelson, Amy J.; Farid, Maha; Michalski, Joel; Kanaji, Nobuhiro; Wang, Xingqi; Basma, Hesham; Patil, Amol; Goraya, Jadvinder; Liu, Xiangde; Togo, Shinsaku; Toews, Myron L.; Holz, Olaf; Muller, Kai-Christian; Magnussen, Helgo; Rennard, Stephen I.
Zeitschriftenaufsatz
2012A reference aerosol generator based on Brownian coagulation in a continuously fed well stirred tank reactor
Koch, W.; Lödding, H.; Pohlmann, G.
Zeitschriftenaufsatz
2012Repeatability of and relationship between potential COPD biomarkers in bronchoalveolar lavage, bronchial biopsies, serum, and induced sputum
Röpcke, S.; Holz, O.; Lauer, G.; Müller, M.; Rittinghausen, S.; Ernst, P.; Lahu, G.; Elmlinger, M.; Krug, N.; Hohlfeld, J.M.
Zeitschriftenaufsatz
2012Reproducibility of serum biomarkers and relationship to airway inflammation following LPS challenge in healthy volunteers
Holz, Olaf; Tan, Lisa; Faulenbach, Cornelia; Müller, Meike; Krug, Norbert; McLeod, Alison; Hohlfeld, Jens M.
Abstract
2012The respiratory tract
Braun, Armin; Ernst, Heinrich; Schaudien, Dirk; Hoymann, Heinz-Gerd; Rittinghausen, Susanne
Aufsatz in Buch
2012Rhinovirus application on the background of allergic airway inflammation in a chronic house dust mite model
Rochlitzer, Sabine; Hoymann, Heinz-Gerd; Müller, Meike; Braun, Armin
Abstract
2012Safety and efficacy of house dust mite allergen challenge in patients with allergic rhinitis using a novel technique for inhalation studies in the Fraunhofer environmental challenge chamber
Lueer, Katrin; Biller, Heike; Windt, Horst; Müller, Meike; Badorrek, Philipp; Haefner, Dietrich; Framke, Theodor; Koch, Armin; Ziehr, Holger; Krug, Norbert; Koch, Wolfgang; Hohlfeld, Jens M.
Abstract
2012Scientific basis for the Soviet and Russian radiofrequency standards for the general public. Review
Repacholi, M.; Grigoriev, Y.; Buschmann, J.; Pioli, C.
Zeitschriftenaufsatz
2012Semi-quantitative assessment of localized pulmonary inflammation by magnetic resonance imaging in patients with mild allergic asthma following segmental allergen challenge
Vogel-Claussen, Jens; Schaumann, Frank; Renne, Julius; Hinrichs, Jan; Schoenfeld, Christian; Gutberlet, Marcel; Hüper, Klaudia; Winkler, Carla; Faulenbach, Cornelia; Krug, Norbert; Wacker, Frank; Hohlfeld, Jens M.
Abstract
2012Sequence error storms and the landscape of mutations in cancer
Kirsch, S.; Klein, C.A.
Zeitschriftenaufsatz
2012Single breath particle characterization to detect small airway alterations
Schwarz, Katharina; Hohlfeld, Jens M.; Biller, Heike; Koch, Wolfgang
Abstract
2012Spontaneously occurring multicentric basal cell carcinoma and keratoacanthomas in a multimammate mouse (Mastomys spp.)
Eydner, M.; Jacobsen, B.; Thomann, M.; Rittinghausen, S.; Fehr, M.; Baumgärtner, W.
Zeitschriftenaufsatz
2012Stable inflammatory phenotype in smokers and smokers with COPD
Holz, Olaf; Roepcke, Stefan; Lauer, Gereon; Krug, Norbert; Ernst, Peter; Lahu, Gezim; Hohlfeld, Jens M.
Abstract
2012Subacute and subchronic inhalation toxicity and dermal absorption of the nanoscaled zinc oxide Z-COTE HP1 in the rat
Creutzenberg, Otto H.; Ziemann, Christina; Hansen, Tanja; Ernst, Heinrich; Schaudien, Dirk; Schuchardt, Sven; Wiench, Karin; Bellmann, Bernd
Zeitschriftenaufsatz
2012Surfactant protein D modulates allergen particle uptake and inflammatory response in a human epithelial airway model
Schleh, Carsten; Rothen-Rutishauser, Barbara M.; Blank, Fabian; Lauenstein, Hans D.; Nassimi, Matthias; Krug, Norbert; Braun, Armin; Erpenbeck, Veit; Gehr, Peter; Hohlfeld, Jens M.
Zeitschriftenaufsatz
2012Suspension of MWCNT for toxicological in vivo and in vitro studies
Heinrich, Uwe; Schlichting, Anja; Ziemann, Christina; Seyock, S.; Haase, D.; Leonhardt, A.; Bellmann, Bernd
Zeitschriftenaufsatz
2012Synthesis of N-Dodecylethanamide-DTTA and characterization by mass spectrometry, NMR and IR spectroscopy
Kongtso, Adeline
: Butenschön, Holger (Erstprüfer); Schuchardt, Sven (Zweitprüfer)
Bachelor Thesis
2012Systemic biomarkers of neutrophilic inflammation, tissue injury and repair in COPD patients with differing levels of desease severity
Cockayne, Debra A.; Cheng, Donovan T.; Waschki, Benjamin; Sridhar, Sriram; Ravindran, Palanikumar; Hilton, Holly; Kourteva, Galina; Bitter, Hans; Pillai, Sreekumar G.; Visvanathan, Sudha; Müller, Kai-Christian; Holz, Olaf; Magnussen, Helgo; Watz, Henrik; Fine, Jay S.
Zeitschriftenaufsatz
2012Toxicology ontology perspectives
Hardy, B.; Apic, G.; Carthew, P.; Clark, D.; Cook, D.; Dix, I.; Escher, S.; Hastings, J.; Heard, D.J.; Jeliazkova, N.; Judson, P.; Matis-Mitchell, S.; Mitic, D.; Myatt, G.; Shah, I.; Spjuth, O.; Tcheremenskaia, O.; Toldo, L.; Watson, D.; White, A.; Yang, C.
Zeitschriftenaufsatz
2012Transient potential channel A1 and mast cell activation in bronchial hyperreactivity caused by hypochlorite and OVA in mice
Hox, V.; Vanoirbeek, J.; Alpizar, Y.A.; Voedisch, S.; Bobic, S.; Callebaut, I.; Vooght, V. de; Sharify, A.; Gerven, L. van; Ceuppens, Jan L.; Vries, A. de; Braun, A.; Hoet, P.; Talavera, K.; Nemery, B.; Hellings, P.
Zeitschriftenaufsatz, Konferenzbeitrag
2012Untersuchungen zur Entwicklung eines Kultivierungsmediums für eine humane Amniocyten-Zelllinie
Müller, Janina
: Lang, Siegmund (Referent); Ziehr, Holger (Koreferent)
Bachelor Thesis
2012Untersuchungen zur Verwendung verschiedener chromatographischer Methoden in der Herstellung und Analytik biopharmazeutischer Plasmide
Füller, Jendrik
: Rau, Udo (Erstgutachter); Ziehr, Holger (Zweitgutachter)
Master Thesis
2012Validation of an EDP assisted model for assessing inhalation exposure and dermal exposure during spraying processes
Koch, Wolfgang; Behnke, Wolfgang; Berger-Preiß, Edith; Kock, Heiko; Gerlin, Susanne; Hahn, Stefan; Schröder, Katrin
Bericht
2012Validierung funktioneller Untersuchungen im Rahmen von Developmental Neurotoxicity Studies entsprechend OECD 426 unter Nutzung einer geeigneten Positivsubstanz
Wehren, Teresa
: Dasenbrock, Clemens (1. Referent)
Master Thesis
2012Verfahren zur Analyse der Ausatemluft
Schwarz, Katharina; Koch, Wolfgang; Windt, Horst; Hohlfeld, Jens; Biller, Heike
Patent
2012Vergleich von Protein A- und Kationenaustauschchromatographie bei der Antikörperaufarbeitung aus Zellkulturüberständen
Geiszkopf, Andy
: Paulsen, Jens (Betreuer)
Bachelor Thesis
2012Vergleich zweier eukaryotischer Expressionssyteme in der Zelllinienentwicklung
Dietrich, Jana
: Biselli, Manfred (Erstprüfer); Veith, Nathalie (Zweitprüfer)
Bachelor Thesis
2012Vergleichende Untersuchungen zur Charakterisierung ultrafeiner Partikel in Rauchen beim Schweißen und bei verwandten Verfahren. Tl.1: Grundlagen der Untersuchung
Pohlmann, Gerhard; Holzinger, Karl; Spiegel-Ciobanu, Vilia E.
Zeitschriftenaufsatz
2012Vergleichende Untersuchungen zur Charakterisierung ultrafeiner Partikel in Rauchen beim Schweißen und bei verwandten Verfahren. Tl.2: Ergebnisse und Diskussion
Pohlmann, Gerhard; Holzinger, Karl; Spiegel-Ciobanu, Vilia E.
Zeitschriftenaufsatz
2012Zelllinienentwicklung und Etablierung einer High-Throughput-Methode zur Optimierung einer plattformbasierten Antikörperaufreinigung
Niermeier, Dennis
: Wittke, Stefan Johannes (Erstprüfer); Harms, Carsten (Zweitprüfer)
Master Thesis
2012Zinc oxide-nanosize does not change the toxicological profile
Wiench, Karin; Schulte, Sabine; Champ, Simon; Ma-Hock, Lan; Schneider, S.; Creutzenberg, Otto; Bellmann, Bernd; Ziemann, Christina; Monteiro-Riviere, Nancy; Revenzwaay, Bernnard; Landsiegel, Robert
Zeitschriftenaufsatz