Fraunhofer-Gesellschaft

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Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2021An automated and high-throughput-screening compatible pluripotent stem cell-based test platform for developmental and reproductive toxicity assessment of small molecule compounds
Witt, Gesa; Keminer, Oliver; Leu, Jennifer; Tandon, Rashmi; Meiser, Ina; Willing, Anne; Winschel, Ingo; Abt, Jana-Christin; Brändl, Björn; Sébastien, Isabelle; Friese, Manuel A.; Müller, Franz Josef; Neubauer, Julia C.; Claussen, Carsten; Zimmermann, Heiko; Gribbon, Philip; Pless, Ole
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2021Bioaccumulation assessment of nanomaterials using freshwater invertebrate species
Kuehr, Sebastian; Kosfeld, Verena; Schlechtriem, Christian
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2021Bioreactor-based antigen production process using the baculovirus expression vector system
Harnischfeger, J.; Käßer, L.; Zitzmann, J.; Salzig, D.; Czermak, P.
Aufsatz in Buch
2021Current State and Future Expectations of Translational Modeling Strategies to Support Drug Product Development, Manufacturing Changes and Controls: A Workshop Summary Report
Pepin, X.J.H.; Parrott, N.; Dressman, J.; Delvadia, P.; Mitra, A.; Zhang, X.; Babiskin, A.; Kolhatkar, V.; Suarez-Sharp, S.
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2021Determination of low environmental free cyanide concentrations in freshwaters
Knopf, Burkhard; Rüdel, Heinz; Hansknecht, Dirk; Klawonn, Thorsten; Kreuzer, Knut
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2021Development of Monoclonal Antibodies against Pea Globulins for Multiplex Assays Targeting Legume Proteins
Lidzba, Norbert; García Arteaga, Verónica; Schiermeyer, Andreas; Havenith, Heide; Muranyi, Isabel; Schillberg, Stefan; Lehmann, Jörg; Ueberham, Elke
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2021The discovery of novel antitrypanosomal 4-phenyl-6-(pyridin-3-yl)pyrimidines
Robinson, W.J.; Taylor, A.E.; Lauga-Cami, S.; Weaver, G.W.; Arroo, R.R.J.; Kaiser, M.; Gul, S.; Kuzikov, M.; Ellinger, B.; Singh, K.; Schirmeister, T.; Botana, A.; Eurtivong, C.; Bhambra, A.S.
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2021Effects of Thermal Stress on the Gut Microbiome of Juvenile Milkfish (Chanos chanos)
Hassenrück, Christiane; Reinwald, Hannes; Kunzmann, Andreas; Tiedemann, Inken; Gärdes, Astrid
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2021Human Mesenchymal Stromal Cells Are Resistant to SARS-CoV-2 Infection under Steady-State, Inflammatory Conditions and in the Presence of SARS-CoV-2-Infected Cells
Schäfer, R.; Spohn, G.; Bechtel, M.; Bojkova, D.; Baer, P.C.; Kuci, S.; Seifried, E.; Ciesek, S.; Cinatl, J.
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2021Improved degradation of azo dyes by lignin peroxidase following mutagenesis at two sites near the catalytic pocket and the application of peroxidase-coated yeast cell walls
Ilić Đurđić, K.; Ostafe, R.; Prodanovic, O.; Đurđević Đelmaš, A.; Popović, N.; Fischer, R.; Schillberg, S.; Prodanovic, R.
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2021Interprofessionelle Versorgung von Patienten mit rheumatoider Arthritis aus hausärztlicher Sicht: Ergebnisse einer Querschnittserhebung
Schneider, E.; Petersen, J.J.; Schulz-Rothe, S.; Gerlach, F.M.; Rossmanith, T.; Siebenhofer, A.; Mergenthal, K.
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2021Lipidomic analysis of local inflammation models shows a specific systemic acute phase response to lipopolysaccharides
Hahnefeld, L.; Kornstädt, L.; Kratz, D.; Ferreiros, N.; Geisslinger, G.; Pierre, S.; Scholich, K.
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2021Predicting the environmental emissions arising from conventional and nanotechnology-related pharmaceutical drug products
Jung, F.; Thurn, M.; Krollik, K.; Gao, G.F.; Hering, I.; Eilebrecht, E.; Emara, Y.; Weiler, M.; Günday-Türeli, N.; Türeli, E.; Parnham, M.J.; Wacker, M.G.
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2021Production of baculovirus and stem cells for baculovirus-mediated gene transfer into human mesenchymal stem cells
Eilts, F.; Harnischfeger, J.; Loewe, D.; Wolff, M.W.; Salzig, D.; Czermak, P.
Aufsatz in Buch
2021The role of environmental specimen banks in monitoring environmental contamination
Chaplow, Jacqueline S.; Bond, Alexander L.; Koschorreck, Jan; Rüdel, Heinz; Shore, Richard F.
Aufsatz in Buch
2021Testing the bioaccumulation potential of manufactured nanomaterials in the freshwater amphipod Hyalella azteca
Kühr, Sebastian; Kaegi, R.; Maletzki, D.; Schlechtriem, C.
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2021Toxicogenomic fin(ger)prints for thyroid disruption AOP refinement and biomarker identification in zebrafish embryos
Reinwald, Hannes; König, Azora; Ayobahan, Steve U.; Alvincz, Julia; Sipos, Levente; Göckener, Bernd; Böhle, Gisela; Shomroni, Orr; Hollert, Henner; Salinas, Gabriela; Schäfers, Christoph; Eilebrecht, Elke; Eilebrecht, Sebastian
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2021Upstream and downstream processes for viral nanoplexes as vaccines
Lothert, K.; Dekevic, G.; Loewe, D.; Salzig, D.; Czermak, P.; Wolff, M.W.
Aufsatz in Buch
202012/15-Lipoxygenase choreographs the resolution of IgG-mediated skin inflammation
Sezin, T.; Ferreiros, N.; Jennrich, M.; Ochirbold, K.; Seutter, M.; Attah, C.; Mousavi, S.; Zillikens, D.; Geisslinger, G.; Sadik, C.D.
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2020ABC transporter DerAB of lactobacillus casei mediates resistance against insect-derived defensins
Revilla-Guarinos, A.; Zhang, Q.; Loderer, C.; Alcántara, C.; Müller, A.; Rahnamaeian, M.; Vilcinskas, A.; Gebhard, S.; Zúñiga, M.; Mascher, T.
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2020Agrocybe aegerita Serves as a Gateway for Identifying Sesquiterpene Biosynthetic Enzymes in Higher Fungi
Zhang, C.; Chen, X.; Orban, A.; Shukal, S.; Birk, F.; Too, H.-P.; Rühl, M.
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2020Alox12/15 Deficiency Exacerbates, While Lipoxin A4 Ameliorates Hepatic Inflammation in Murine Alcoholic Hepatitis
Queck, A.; Fink, A.F.; Sirait-Fischer, E.; Rüschenbaum, S.; Thomas, D.; Snodgrass, R.G.; Geisslinger, G.; Baba, H.A.; Trebicka, J.; Zeuzem, S.; Weigert, A.; Lange, C.M.; Brüne, B.
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2020Alternatives to Growth. Climax Economy Modelled on Ecology
Schäfers, Christoph; Bette, Kristina; Herrmann, Florian; Nawroth, Georg
Aufsatz in Buch
2020Analysis of potential risk factors of caprine coccidiosis
Silva, L.M.R.; Carrau, T.; Vila-Viçosa, M.J.M.; Musella, V.; Rinaldi, L.; Failing, K.; Cortes, H.C.E.; Taubert, A.; Hermosilla, C.
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2020Angiotensin II treatment in COVID-19 patients: More risk than benefit? A single-center experience
Heinicke, U.; Adam, E.; Sonntagbauer, M.; Knethen, A. von; Zacharowski, K.; Neb, H.
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2020Anthelminthic Activity of Assassin Bug Venom against the Blood Fluke Schistosoma mansoni
Tonk, M.; Vilcinskas, A.; Grevelding, C.G.; Haeberlein, S.
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2020Antimicrobial peptides from rat-tailed maggots of the drone fly Eristalis tenax show potent activity against multidrug-resistant gram-negative bacteria
Hirsch, R.; Wiesner, J.; Bauer, A.; Marker, A.; Vogel, H.; Hammann, P.E.; Vilcinskas, A.
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2020Application of General Unified Threshold Models of Survival Models for Regulatory Aquatic Pesticide Risk Assessment Illustrated with an Example for the Insecticide Chlorpyrifos
Brock, T.; Arena, M.; Cedergreen, N.; Charles, S.; Duquesne, S.; Ippolito, A.; Klein, M.; Reed, M.; Teodorovic, I.; Brink, P.J. van den; Focks, A.
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2020Aquatic suspended particulate matter as source of eDNA for fish metabarcoding
Diaz, Cecilia; Wege, Franziska-Frederike; Tang, Cuong Q.; Crampton‑Platt, Alexandra; Rüdel, Heinz; Eilebrecht, Elke; Koschorreck, Jan
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2020Aspergillus sydowii: Genome Analysis and Characterization of Two Heterologous Expressed, Non-redundant Xylanases
Brandt, S.C.; Ellinger, B.; Nguyen, T. van; Harder, S.; Schlüter, H.; Hahnke, R.L.; Rühl, M.; Schäfer, W.; Gand, M.
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2020Assessment of SARS-CoV-2 Transmission on an International Flight and Among a Tourist Group
Hoehl, S.; Karaca, O.; Kohmer, N.; Westhaus, S.; Graf, J.; Goetsch, U.; Ciesek, S.
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2020Attachment efficiency of nanomaterials to algae as an important criterion for ecotoxicity and grouping
Hund-Rinke, K.; Sinram, T.; Schlich, K.; Nickel, C.; Dickehut, H.P.; Schmidt, M.; Kühnel, D.
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2020Author Correction: A new antibiotic selectively kills Gram-negative pathogens (Nature, 10.1038/s41586-019-1791-1)
Imai, Y.; Meyer, K.J.; Iinishi, A.; Favre-Godal, Q.; Green, R.; Manuse, S.; Caboni, M.; Mori, M.; Niles, S.; Ghiglieri, M.; Honrao, C.; Ma, X.; Guo, J.J.; Makriyannis, A.; Linares-Otoya, L.; Böhringer, N.; Wuisan, Z.G.; Kaur, H.; Wu, R.; Mateus, A.; Typas, A.; Savitski, M.M.; Espinoza, J.L.; O’Rourke, A.; Nelson, K.E.; Hiller, S.; Noinaj, N.; Schäberle, T.F.; d'Onofrio, A.; Lewis, K.
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2020Bicistronic expression and differential localization of proteins in insect cells and Drosophila suzukii using picornaviral 2A peptides
Schwirz, J.; Yan, Y.; Franta, Z.; Schetelig, M.F.
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2020Bildgebung bei der Psoriasisarthritis und Aspekte der röntgenologischen Progression
Baraliakos, X.; Kleyer, A.; Simon, D.; Köhm, M.; Ohrndorf, S.; Sewerin, P.
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2020Bioavailability of silver from wastewater and planktonic food borne silver nanoparticles in the rainbow trout Oncorhynchus mykiss
Zeumer, Richard; Hermsen, Lara; Kägi, Ralf; Kühr, Sebastian; Knopf, Burkhard; Schlechtriem, Christian
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2020Bioconcentration, metabolism and spatial distribution of 14C‐labelled laurate in the freshwater amphipod Hyalella Azteca
Raths, Johannes; Kühr, Sebastian; Schlechtriem, Christian
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2020Biodegradation testing of volatile hydrophobic chemicals in water-sediment systems - Experimental developments and challenges
Shresta, Prasit; Meisterjahn, Boris; Hughes, Christopher B.; Mayer, Philipp; Birch, Heidi; Hennecke, Dieter
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2020Biomagnification of ionizable organic compounds in rainbow trout Oncorhynchus mykiss
Mueller, Carolin; Trapp, Stefan; Polesel, Fabio; Kuehr, Sebastian; Schlechtriem, Christian
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2020Biorelevant Two-Stage In Vitro Testing for rDCS Classification and in PBPK Modeling - Case Example Ritonavir
Fiolka, T.; Abeele, J. Van Den; Augustijns, P.; Arora, S.; Dressman, J.
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2020Biotechnological Production of Odor-Active Methyl-Branched Aldehydes by a Novel α-Dioxygenase from Crocosphaera subtropica
Hammer, A.K.; Albrecht, F.; Hahne, F.; Jordan, P.; Fraatz, M.A.; Ley, J.; Geissler, T.; Schrader, J.; Zorn, H.; Buchhaupt, M.
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2020Biotechnologically produced fucosylated oligosaccharides inhibit the binding of human noroviruses to their natural receptors
Derya, S.M.; Spiegel, H.; Hanisch, F.-G.; Morozov, V.; Schroten, H.; Jennewein, S.; Parschat, K.
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2020Biotransformation Changes Bioaccumulation and Toxicity of Diclofenac in Aquatic Organisms
Fu, Qiuguo; Fedrizzi, Davide; Kosfeld, Verena; Schlechtriem, Christian; Ganz, Vera; Derrer, Samuel; Rentsch, Daniel; Hollender, Juliane
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2020Biowaiver Monograph for Immediate-Release Solid Oral Dosage Forms: Moxifloxacin Hydrochloride
Charoo, N.A.; Abdallah, D.B.; Parveen, T.; Abrahamsson, B.; Cristofoletti, R.; Groot, D.W.; Langguth, P.; Parr, A.; Polli, J.E.; Mehta, M.; Shah, V.P.; Tajiri, T.; Dressman, J.
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2020Biowaiver Monographs for Immediate Release Solid Oral Dosage Forms: Cephalexin Monohydrate
Plöger, G.F.; Quizon, P.M.; Abrahamsson, B.; Cristofoletti, R.; Groot, D.W.; Parr, A.; Langguth, P.; Polli, J.E.; Shah, V.P.; Tajiri, T.; Mehta, M.U.; Dressman, J.
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2020Bone Marrow Mononuclear Cells Activate Angiogenesis via Gap Junction-Mediated Cell-Cell Interaction
Kikuchi-Taura, A.; Okinaka, Y.; Takeuchi, Y.; Ogawa, Y.; Maeda, M.; Kataoka, Y.; Yasui, T.; Kimura, T.; Gul, S.; Claussen, C.; Boltze, J.; Taguchi, A.
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2020Branched-chain fatty acids as mediators of the activation of hepatic peroxisome proliferator-activated receptor alpha by a fungal lipid extract
Maheshwari, G.; Ringseis, R.; Wen, G.; Gessner, D.K.; Rost, J.; Fraatz, M.A.; Zorn, H.; Eder, K.
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2020Brief clinical evaluation of six high-throughput SARS-CoV-2 IgG antibody assays
Kohmer, N.; Westhaus, S.; Rühl, C.; Ciesek, S.; Rabenau, H.F.
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2020Canakinumab for Treatment of Adult-Onset Still's Disease to Achieve Reduction of Arthritic Manifestation (CONSIDER): Phase II, randomised, double-blind, placebo-controlled, multicentre, investigator-initiated trial
Kedor, C.; Listing, J.; Zernicke, J.; Weiß, A.; Behrens, F.; Blank, N.; Henes, J.C.; Kekow, J.; Rubbert-Roth, A.; Schulze-Koops, H.; Seipelt, E.; Specker, C.; Feist, E.
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2020Cell-Type Targeted NF-kappaB Inhibition for the Treatment of Inflammatory Diseases
Sehnert, B.; Burkhardt, H.; Dübel, S.; Voll, R.E.
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2020Central encoding of the strength of intranasal chemosensory trigeminal stimuli in a human experimental pain setting
Lötsch, J.; Oertel, B.G.; Felden, L.; Nöth, U.; Deichmann, R.; Hummel, T.; Walter, C.
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2020Ceramide synthase 5 deficiency aggravates dextran sodium sulfate-induced colitis and colon carcinogenesis and impairs T-cell activation
El-Hindi, K.; Brachtendorf, S.; Hartel, J.C.; Oertel, S.; Birod, K.; Trautmann, S.; Thomas, D.; Ulshöfer, T.; Weigert, A.; Utermöhlen, O.; Krönke, M.; Grösch, S.
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2020Characterization of the Nutritional Composition of a Biotechnologically Produced Oyster Mushroom and its Physiological Effects in Obese Zucker Rats
Maheshwari, G.; Gessner, D.K.; Meyer, S.; Ahlborn, J.; Wen, G.; Ringseis, R.; Zorn, H.; Eder, K.
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2020Chemical starting matter for HNF4α ligand discovery and chemogenomics
Meijer, I.; Willems, S.; Ni, X.; Heering, J.; Chaikuad, A.; Merk, D.
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2020Chemicals of emerging concern in marine specimens of the German Environmental Specimen Bank
Fliedner, Annette; Rüdel, Heinz; Dreyer, Annekatrin; Pirntke, Ulrike; Koschorreck, Jan
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2020Chronic effects of wastewater-borne silver and titanium dioxide nanoparticles on the rainbow trout (Oncorhynchus mykiss)
Zeumer, Richard; Galhano, Victor; Monteiro, Marta S.; Kühr, Sebastian; Knopf, Burkhard; Meisterjahn, Boris; Soares, Amadeu M.V.M.; Loureiro, Susana; Lopes, Isabel; Schlechtriem, Christian
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2020Collecting data through high throughput in vitro early toxicity and off-target liability assays to rapidly identify limitations of novel thyromimetics
Runfola, M.; Sestito, S.; Gul, S.; Chiellini, G.; Rapposelli, S.
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2020Combinatorial metabolic engineering in saccharomyces cerevisiae for the enhanced production of the fpp-derived sesquiterpene germacrene
Bröker, J.N.; Müller, B.; Prüfer, D.; Gronover, C.S.
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2020Combining biorelevant in vitro and in silico tools to investigate the in vivo performance of the amorphous solid dispersion formulation of etravirine in the fed state
Litou, C.; Turner, D.B.; Holmstock, N.; Ceulemans, J.; Box, K.J.; Kostewicz, E.; Kuentz, M.; Holm, R.; Dressman, J.
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2020Comparative proteome and metabolome analyses of latex-exuding and non-exuding Taraxacum koksaghyz roots provide insights into laticifer biology
Benninghaus, V.A.; Deenen, N. van; Müller, B.; Roelfs, K.-U.; Lassowskat, I.; Finkemeier, I.; Prüfer, D.; Schulze Gronover, C.
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2020Comparison of Alternative Methods for Bioaccumulation Assessment: Scope and Limitations of In Vitro Depletion Assays with Rainbow Trout and Bioconcentration Tests in the Freshwater Amphipod Hyalella azteca
Kosfeld, Verena; Fu, Qiuguo; Ebersbach, Ina; Esser, Dana; Schauerte, Anna; Bischof, Ina; Hollender, Juliane; Schlechtriem, Christian
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2020Comprehensive analysis of all evolutionary paths between two divergent PDZ domain specificities
Teyra, J.; Ernst, A.; Singer, A.; Sicheri, F.; Sidhu, S.S.
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2020Comprehensive evaluation of the metabolic effects of insect meal from Tenebrio molitor L. in growing pigs by transcriptomics, metabolomics and lipidomics
Meyer, S.; Gessner, D.K.; Braune, M.S.; Friedhoff, T.; Most, E.; Höring, M.; Liebisch, G.; Zorn, H.; Eder, K.; Ringseis, R.
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2020Conformation-specific inhibitors of activated Ras GTPases reveal limited Ras dependency of patient-derived cancer organoids
Wiechmann, S.; Maisonneuve, P.; Grebbin, B.M.; Hoffmeister, M.; Kaulich, M.; Clevers, H.; Rajalingam, K.; Kurinov, I.; Farin, H.F.; Sicheri, F.; Ernst, A.
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2020Correction to: Sustained improvement in work outcomes in employed patients with rheumatoid arthritis during 2 years of adalimumab therapy: An observational cohort study
Behrens, F.; Tony, H.-P.; Koehm, M.; Schwaneck, E.C.; Gnann, H.; Greger, G.; Burkhardt, H.; Schmalzing, M.
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2020COVID-19-Related Coagulopathy - Is Transferrin a Missing Link?
McLaughlin, K.-M.; Bechtel, M.; Bojkova, D.; Münch, C.; Ciesek, S.; Wass, M.N.; Michaelis, M.; Cinatl, J.
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2020CRISPR/Cas9 mediated disruption of the white gene leads to pigmentation deficiency and copulation failure in Drosophila suzukii
Yan, Y.; Ziemek, J.; Schetelig, M.F.
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2020Current projection methods-induced biases at subgroup detection for machine-learning based data-analysis of biomedical data
Lötsch, J.; Ultsch, A.
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2020A data science approach to the selection of most informative readouts of the human intradermal capsaicin pain model to assess pregabalin effects
Lötsch, J.; Walter, C.; Zunftmeister, M.; Zinn, S.; Wolters, M.; Ferreiros, N.; Rossmanith, T.; Oertel, B.G.; Geisslinger, G.
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2020A data science-based analysis of seasonal patterns in outpatient presentations due to olfactory dysfunction
Lötsch, J.; Hummel, T.
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2020Data-science-based subgroup analysis of persistent pain during 3 years after breast cancer surgery: A prospective cohort study
Lötsch, J.; Ultsch, A.; Kalso, E.
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2020Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis
Runfola, M.; Sestito, S.; Bellusci, L.; Pietra, V. la; D'Amore, V.M.; Kowalik, M.A.; Chiellini, G.; Gul, S.; Perra, A.; Columbano, A.; Marinelli, L.; Novellino, E.; Rapposelli, S.
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2020Design, Synthesis, and Structure - Activity Relationship Studies of Dual Inhibitors of Soluble Epoxide Hydrolase and 5-Lipoxygenase
Hiesinger, K.; Kramer, J.S.; Beyer, S.; Eckes, T.; Brunst, S.; Flauaus, C.; Wittmann, S.K.; Weizel, L.; Kaiser, A.; Kretschmer, S.B.M.; George, S.; Angioni, C.; Heering, J.; Geisslinger, G.; Schubert-Zsilavecz, M.; Schmidtko, A.; Pogoryelov, D.; Pfeilschifter, J.; Hofmann, B.; Steinhilber, D.; Schwalm, S.; Proschak, E.
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2020Detection of biomarkers to differentiate endocrine disruption from hepatotoxicity in zebrafish (Danio rerio) using proteomics
Ayobahan, Steve U.; Eilebrecht, Sebastian; Baumann, Lisa; Teigeler, Matthias; Hollert, Henner; Kalkhof, Stefan; Eilebrecht, Elke; Schäfers, Christoph
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2020Development of a downstream process for the production of an inactivated whole hepatitis C virus vaccine
Lothert, K.; Offersgaard, A.F.; Pihl, A.F.; Mathiesen, C.K.; Jensen, T.B.; Alzua, G.P.; Fahnøe, U.; Bukh, J.; Gottwein, J.M.; Wolff, M.W.
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2020Development of a method to determine the bioaccumulation of manufactured nanomaterials in filtering organisms (Bivalvia). Final Report
Schlechtriem, Christian; Knopf, Burkhard; Kühr, Sebastian; Meisterjahn, Boris; Schröder, Nicola
Bericht
2020Development of a solventless stir bar sorptive extraction/thermal desorption large volume injection capillary gas chromatographic-mass spectrometric method for ultra-trace determination of pyrethroids pesticides in river and tap water samples
Sargazi, Mona; Bücking, Mark; Kaykhaii, Massoud
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2020Development of a test method for transformation of veterinary pharmaceuticals and biocides in anaerobic liquid manure
Junker, Thomas; Atorf, Cornelia; Berkner, Silvia; Düring, Rolf-Alexander; Hennecke, Dieter; Herrchen, Monika; Konradi, Sabine; Merrettig‑Bruns, Ute; Römbke, Jörg; Wagner, Julia; Weinfurtner, Karlheinz
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2020Discovery of Protein-Protein Interaction Inhibitors by Integrating Protein Engineering and Chemical Screening Platforms
Maculins, T.; Garcia-Pardo, J.; Skenderovic, A.; Gebel, J.; Putyrski, M.; Vorobyov, A.; Busse, P.; Varga, G.; Kuzikov, M.; Zaliani, A.; Rahighi, S.; Schaeffer, V.; Parnham, M.J.; Sidhu, S.S.; Ernst, A.; Dötsch, V.; Akutsu, M.; Dikic, I.
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2020Disrupting the LC3 Interaction Region (LIR) Binding of Selective Autophagy Receptors Sensitizes AML Cell Lines to Cytarabine
Putyrski, M.; Vakhrusheva, O.; Bonn, F.; Guntur, S.; Vorobyov, A.; Brandts, C.; Dikic, I.; Ernst, A.
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2020Dissolution testing of modified release products with biorelevant media: An OrBiTo ring study using the USP apparatus III and IV
Reppas, C.; Vrettos, N.-N.; Dressman, J.; Andreas, C.J.; Miyaji, Y.; Brown, J.; Etherson, K.; Hanley, S.; Karkossa, F.; Karlsson, E.; Klein, S.; Maier, G.-M.; McAllister, M.; Mistry, N.; Rosenblatt, K.; Schäfer, K.J.; Smith, K.L.; Tomaszewska, I.; Williams, J.; Winge, F.; Vertzoni, M.
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2020Distribution Optimization: An evolutionary algorithm to separate Gaussian mixtures
Lerch, F.; Ultsch, A.; Lötsch, J.
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2020The disturbed iron phenotype of tumor cells and macrophages in renal cell carcinoma influences tumor growth
Schnetz, M.; Meier, J.K.; Rehwald, C.; Mertens, C.; Urbschat, A.; Tomat, E.; Akam, E.A.; Baer, P.; Roos, F.C.; Brüne, B.; Jung, M.
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2020Does concomitant methotrexate confer clinical benefits in patients treated with prior biologic therapy?
Schmalzing, M.; Behrens, F.; Schwaneck, E.C.; Koehm, M.; Greger, G.; Gnann, H.; Burkhardt, H.; Tony, H.-P.
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2020Does Light Color Temperature Influence Aspects of Oviposition by the Black Soldier Fly (Diptera: Stratiomyidae)?
Klüber, P.; Bakonyi, D.; Zorn, H.; Rühl, M.
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2020Dual Farnesoid X Receptor/Soluble Epoxide Hydrolase Modulators Derived from Zafirlukast
Schierle, S.; Helmstädter, M.; Schmidt, J.; Hartmann, M.; Horz, M.; Kaiser, A.; Weizel, L.; Heitel, P.; Proschak, A.; Hernandez-Olmos, V.; Proschak, E.; Merk, D.
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2020An economic dilemma between molecular weapon systems may explain an arachno-atypical venom in wasp spiders (Argiope bruennichi)
Lüddecke, T.; von Reumont, B.M.; Förster, F.; Billion, A.; Timm, T.; Lochnit, G.; Vilcinskas, A.; Lemke, S.
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2020Ectopic bone formation and systemic bone loss in a transmembrane TNF-driven model of human spondyloarthritis
Christodoulou-Vafeiadou, E.; Geka, C.; Ntari, L.; Kranidioti, K.; Argyropoulou, E.; Meier, F.; Armaka, M.; Mourouzis, I.; Pantos, C.; Rouchota, M.; Loudos, G.; Denis, M.C.; Karagianni, N.; Kollias, G.
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2020The endocannabinoid anandamide has an anti-inflammatory effect on CCL2 expression in vascular smooth muscle cells
Pflüger-Müller, B.; Oo, J.A.; Heering, J.; Warwick, T.; Proschak, E.; Günther, S.; Looso, M.; Rezende, F.; Fork, C.; Geisslinger, G.; Thomas, D.; Gurke, R.; Steinhilber, D.; Schulz, M.; Leisegang, M.S.; Brandes, R.P.
Zeitschriftenaufsatz
2020Environmental hazard testing of nanobiomaterials
Amorim, M.J.B.; Fernández-Cruz, M.L.; Hund-Rinke, K.; Scott-Fordsmand, J.J.
Zeitschriftenaufsatz
2020Epidemiological screening of captive salamanders reveals current absence of batrachochytrium salamandrivorans in private collections throughout the federal state of Hesse (Germany)
Jung, L.; Dusek, J.; Lüddecke, T.; Schulz, V.; Maier-Sam, K.; Habich, L.; Mosebach, A.; Lierz, M.; Ziemek, H.-P.
Zeitschriftenaufsatz
2020Establishing virtual bioequivalence and clinically relevant specifications using in vitro biorelevant dissolution testing and physiologically-based population pharmacokinetic modeling. Case example: Naproxen
Loisios-Konstantinidis, I.; Cristofoletti, R.; Fotaki, N.; Turner, D.B.; Dressman, J.
Zeitschriftenaufsatz
2020Establishment and Characterization of a Unilateral UV-Induced Photoreceptor Degeneration Model in the C57Bl/6J Mouse
Meer, A.-M. van der; Berger, T.; Müller, F.; Foldenauer, A.C.; Johnen, S.; Walter, P.
Zeitschriftenaufsatz
2020Ether lipid and sphingolipid expression patterns are estrogen receptor-dependently altered in breast cancer cells
Hahnefeld, L.; Gruber, L.; Schömel, N.; Fischer, C.; Mattjus, P.; Gurke, R.; Beretta, M.; Ferreirós, N.; Geisslinger, G.; Wegner, M.-S.
Zeitschriftenaufsatz
2020European medicinal leeches - New roles in modern medicine
Lemke, S.; Vilcinskas, A.
Zeitschriftenaufsatz
2020Evaluation of Differences in Dosage Form Performance of Generics Using BCS-Based Biowaiver Specifications and Biopharmaceutical Modeling
Hofsäss, M.A.; Dressman, J.
Zeitschriftenaufsatz
2020Evaluation of potential environmental toxicity of polymeric nanomaterials and surfactants
Hering, Indra; Eilebrecht, Elke; Parnham, Michael J.; Günday-Türeli, Nazende; Türeli, Akif Emre; Weiler, Marc; Schäfers, Christoph; Fenske, Martina; Wacker, Matthias G.
Zeitschriftenaufsatz
2020Evaluation of the risk for soil organisms under real conditions
Toschki, Andreas; Hammers-Wirtz, Monika; Poßberg, Claudia; Ross-Nickoll, Martina; Schäffer, Andreas; Schmidt, Burkhard; Scholz Starke, Björn; Römbke, Jörg; Scheffzyk, Adam; Klein, Michael; Hommen, Udo
Bericht
2020Evidence of SARS-CoV-2 Infection in Returning Travelers from Wuhan, China
Ciesek, Sandra
Zeitschriftenaufsatz
2020Exercise-Induced Changes in Bioactive Lipids Might Serve as Potential Predictors of Post-Exercise Hypotension. A Pilot Study in Healthy Volunteers
Wolters, M.C.; Schmetzer, J.; Möser, C.V.; Hahnefeld, L.; Angioni, C.; Thomas, D.; Ferreirós, N.; Geisslinger, G.; Niederberger, E.
Zeitschriftenaufsatz
2020Exploring CYP2J2: Lipid mediators, inhibitors and therapeutic implications
Sisignano, M.; Steinhilber, D.; Parnham, M.J.; Geisslinger, G.
Zeitschriftenaufsatz
2020Factors determining microbial colonization of liquid nitrogen storage tanks used for archiving biological samples
Bajerski, F.; Bürger, A.; Glasmacher, B.; Keller, E.R.J.; Müller, K.; Mühldorfer, K.; Nagel, M.; Rüdel, H.; Müller, T.; Schenkel, J.; Overmann, J.
Zeitschriftenaufsatz
2020Fate of acrylamide during coffee roasting and in vitro digestion assessed with carbon 14- and carbon 13-labeled materials
Badoud, Flavia; Göckener, Bernd; Severin, Kevin; Ernest, Marion; Romero, Roman; Alzieu, Thibaut; Glabasnia, Arne; Hamel, Jonas; Bücking, Mark; Delatour, Thierry
Zeitschriftenaufsatz
2020Fate of Chlorpropham during High-Temperature Processing of Potatoes
Göckener, Bernd; Kotthoff, Matthias; Kling, Hans-Willi; Bücking, Mark
Zeitschriftenaufsatz
2020A field study in support of the monitoring of priority substances in German freshwater fish: Derivation of fillet-to-whole fish conversion factors
Rüdel, Heinz; Radermacher, Georg; Fliedner, Annette; Lohmann, Nina; Duffek, Anja
Zeitschriftenaufsatz
2020First Structure-Activity Relationship Study of Potent BLT2 Agonists as Potential Wound-Healing Promoters
Hernandez-Olmos, V.; Heering, J.; Planz, V.; Liu, T.; Kaps, A.; Rajkumar, R.; Gramzow, M.; Kaiser, A.; Schubert-Zsilavecz, M.; Parnham, M.J.; Windbergs, M.; Steinhilber, D.; Proschak, E.
Zeitschriftenaufsatz
2020Flow cytometry-based system for screening of lignin peroxidase mutants with higher oxidative stability
Ilić Đurđić, K.; Ece, S.; Ostafe, R.; Vogel, S.; Balaž, A.M.; Schillberg, S.; Fischer, R.; Prodanovic, R.
Zeitschriftenaufsatz
2020Fraunhofer-Institut für Molekularbiologie und Angewandte Oekologie. Jahresbericht 2019
 
Jahresbericht
2020From cancer to immune-mediated diseases and tolerance induction: Lessons learned from immune oncology and classical anti-cancer treatment
Klöß, Stephan; Dehmel, Susann; Braun, Armin; Parnham, Michael J.; Koehl, Ulrike; Schiffmann, Susanne
Zeitschriftenaufsatz
2020Das frühe Erkennen postoperativen Nierenversagens nach offener thorakoabdomineller Aortenchirurgie: Eine multizentrische Observationsstudie (Nephrocheck™-TAAA-Trial)
Gombert, A.; Oberhuber, A.; Greiner, A.; Eierhoff, T.; Heine, B.; Omran, S.; Frese, J.; Doukas, P.; Foldenauer, A.-C.; Jacobs, M.J.
Zeitschriftenaufsatz
2020Frühe, zeitlich begrenzte intensive immunmodulatorische Therapie zum Erreichen einer Remission in Psoriasis Arthritis
Köhm, M.
Zeitschriftenaufsatz
2020Function of Cathepsin K in the Central Nervous System of Male Mice is Independent of its Role in the Thyroid Gland
Dauth, S.; Rakov, H.; Sîrbulescu, R.F.; Ilieş, I.; Weber, J.; Batbajar Dugershaw, B.; Braun, D.; Rehders, M.; Wirth, E.K.; Führer, D.; Schweizer, U.; Brix, K.
Zeitschriftenaufsatz
2020Functional Characterization of Knock-In Mice Expressing a 12/15-Lipoxygenating Alox5 Mutant Instead of the 5-Lipoxygenating Wild-Type Enzyme
Marbach-Breitrück, E.; Kutzner, L.; Rothe, M.; Gurke, R.; Schreiber, Y.; Reddanna, P.; Schebb, N.-H.; Stehling, S.; Wieler, L.H.; Heydeck, D.; Kuhn, H.
Zeitschriftenaufsatz
2020Functional characterization of the Drosophila suzukii pro-apoptotic genes reaper, head involution defective and grim
Jaffri, S.A.; Yan, Y.; Schwirz, J.; Schetelig, M.F.
Zeitschriftenaufsatz
2020The Fundamental Clustering and Projection Suite (FCPS)
Ultsch, A.; Lötsch, J.
Zeitschriftenaufsatz
2020Gene expression variability between randomly and targeted transgene integration events in tobacco suspension cell lines
Kirchhoff, Janina; Schiermeyer, Andreas; Schneider, Katja; Fischer, Rainer; Ainley, W. Michael; Webb, Steven R.; Schinkel, Helga; Schillberg, Stefan
Zeitschriftenaufsatz
2020Genetic variants in FBLIM1 gene do not contribute to SAPHO syndrome and chronic recurrent multifocal osteomyelitis in typical patient groups
Assmann, G.; Köhm, M.; Schuster, V.; Behrens, F.; Mössner, R.; Magnolo, N.; Oji, V.; Burkhardt, H.; Hüffmeier, U.
Zeitschriftenaufsatz
2020Global occurrence, chemical properties, and ecological impacts of e-wastes (IUPAC technical report)
Purchase, Diane; Abbasi, Golnoush; Bisschop, Lieselot; Chatterjee, Debashish; Ekberg, Christian; Ermolin, Mikhail; Fedotov, Petr; Garelick, Hemda; Isimekhai, Khadijah; Kandile, Nadia G.; Lundström, Mari; Matharu, Avtar; Miller, Bradley W.; Pineda, Antonio; Popoola, Oluseun E.; Retegan, Teodora; Ruedel, Heinz; Serpe, Angela; Sheva, Yehuda; Surati, Kiran R.; Walsh, Fiona; Wilson, Benjamin P.; Wong, Ming Hung
Zeitschriftenaufsatz
2020Glucagon-like peptide 1 levels predict cardiovascular risk in patients with acute myocardial infarction
Kahles, F.; Rückbeil, M.V.; Mertens, R.W.; Foldenauer, A.C.; Arrivas, M.C.; Moellmann, J.; Lebherz, C.; Biener, M.; Giannitsis, E.; Katus, H.A.; Marx, N.; Lehrke, M.
Zeitschriftenaufsatz
2020The gram-positive bacterium Leuconostoc pseudomesenteroides shows insecticidal activity against drosophilid and aphid pests
Hiebert, N.; Kessel, T.; Skaljac, M.; Spohn, M.; Vilcinskas, A.; Lee, K.-Z.
Zeitschriftenaufsatz
2020Growth Factor Receptor Signaling Inhibition Prevents SARS-CoV-2 Replication
Klann, K.; Bojkova, D.; Tascher, G.; Ciesek, S.; Münch, C.; Cinatl, J.
Zeitschriftenaufsatz
2020The gut and feed residue microbiota changing during the rearing of Hermetia illucens larvae
Cifuentes, Y.; Glaeser, S.P.; Mvie, J.; Bartz, J.-O.; Müller, A.; Gutzeit, H.O.; Vilcinskas, A.; Kämpfer, P.
Zeitschriftenaufsatz
2020Halogenation‐Guided Chemical Screening Provides Insight into Tjipanazole Biosynthesis by the Cyanobacterium Fischerella ambigua
Chilczuk, T.; Schäberle, T.F.; Vahdati, S.; Mettal, U.; El Omari, M.; Enke, H.; Wiese, M.; König, G.M.; Niedermeyer, T.H.J.
Zeitschriftenaufsatz
2020A head-to-head comparison of the efficacy and safety of ixekizumab and adalimumab in biological-naïve patients with active psoriatic arthritis: 24-week results of a randomised, open-label, blinded-assessor trial
Mease, P.J.; Smolen, J.S.; Behrens, F.; Nash, P.; Liu Leage, S.; Li, L.; Tahir, H.; Gooderham, M.; Krishnan, E.; Liu-Seifert, H.; Emery, P.; Pillai, S.G.; Helliwell, P.S.
Zeitschriftenaufsatz
2020High Glucosylceramides and Low Anandamide Contribute to Sensory Loss and Pain in Parkinson's Disease
Klatt-Schreiner, K.; Valek, L.; Kang, J.-S.; Khlebtovsky, A.; Trautmann, S.; Hahnefeld, L.; Schreiber, Y.; Gurke, R.; Thomas, D.; Wilken-Schmitz, A.; Wicker, S.; Auburger, G.; Geisslinger, G.; Lötsch, J.; Pfeilschifter, W.; Djaldetti, R.; Tegeder, I.
Zeitschriftenaufsatz
2020A high-throughput HIV-1 drug screening platform, based on lentiviral vectors and compatible with biosafety level-1
Ellinger, B.; Pohlmann, D.; Woens, J.; Jäkel, F.M.; Reinshagen, J.; Stocking, C.; Prassolov, V.S.; Fehse, B.; Riecken, K.
Zeitschriftenaufsatz
2020Highlights of the 12th Wartburg Symposium on Flavor Chemistry & Biology
Zorn, H.; Hofmann, T.; Dawid, C.
Zeitschriftenaufsatz
2020Histone deacetylation inhibitors as modulators of regulatory T cells
Knethen, A. von; Heinicke, U.; Weigert, A.; Zacharowski, K.; Brüne, B.
Zeitschriftenaufsatz
2020Human biomonitoring of per- and polyfluoroalkyl substances in German blood plasma samples from 1982 to 2019
Göckener, Bernd; Weber, Till; Rüdel, Heinz; Bücking, Mark; Kolossa-Gehring, Marike
Zeitschriftenaufsatz
2020Human iPSC-Derived Blood-Brain Barrier Models: Valuable Tools for Preclinical Drug Discovery and Development?
Appelt-Menzel, Antje; Oerter, Sabrina; Mathew, Sanjana; Haferkamp, Undine; Hartmann, Carla; Jung, Matthias; Neuhaus, Winfried; Pless, Ole
Zeitschriftenaufsatz
2020Hypoxia inhibits ferritinophagy, increases mitochondrial ferritin, and protects from ferroptosis
Fuhrmann, D.C.; Mondorf, A.; Beifuß, J.; Jung, M.; Brüne, B.
Zeitschriftenaufsatz
2020Identification and molecular analysis of interaction sites in the MtSEO-F1 protein involved in forisome assembly
Rose, J.; Visser, F.; Müller, B.; Senft, M.; Groscurth, S.; Sicking, K.F.; Twyman, R.M.; Prüfer, D.; Noll, G.A.
Zeitschriftenaufsatz
2020Identification of a 2,4-diaminopyrimidine scaffold targeting Trypanosoma brucei pteridine reductase 1 from the LIBRA compound library screening campaign
Linciano, P.; Cullia, G.; Borsari, C.; Santucci, M.; Ferrari, S.; Witt, G.; Gul, S.; Kuzikov, M.; Ellinger, B.; Santarem, N.; Cordeiro da Silva, A.; Conti, P.; Bolognesi, M.L.; Roberti, M.; Prati, F.; Bartoccini, F.; Retini, M.; Piersanti, G.; Cavalli, A.; Goldoni, L.; Bertozzi, S.M.; Bertozzi, F.; Brambilla, E.; Rizzo, V.; Piomelli, D.; Pinto, A.; Bandiera, T.; Costi, M.P.
Zeitschriftenaufsatz
2020Identification of entomopathogenic bacteria associated with the invasive pest Drosophila suzukii in infested areas of Germany
Hiebert, N.; Carrau, T.; Bartling, M.; Vilcinskas, A.; Lee, K.-Z.
Zeitschriftenaufsatz
2020Identification, cloning, expression and functional interrogation of the biosynthetic pathway of the polychlorinated triphenyls ambigol A-C from Fischerella ambigua 108b
Duell, E.R.; Milzarek, T.M.; El Omari, M.; Linares-Otoya, L.J.; Schäberle, T.F.; König, G.M.; Gulder, T.A.M.
Zeitschriftenaufsatz
2020IL-36 family cytokines in protective versus destructive inflammation
Han, Y.; Huard, A.; Mora, J.; da Silva, P.; Brüne, B.; Weigert, A.
Zeitschriftenaufsatz
2020Immune Checkpoint Blockade Improves Chemotherapy in the PyMT Mammary Carcinoma Mouse Model
Sirait-Fischer, E.; Olesch, C.; Fink, A.F.; Berkefeld, M.; Huard, A.; Schmid, T.; Takeda, K.; Brüne, B.; Weigert, A.
Zeitschriftenaufsatz
2020Impact of hyperhomocysteinemia and different dietary interventions on cognitive performance in a knock-in mouse model for alzheimer's disease
Nieraad, H.; de Bruin, N.; Arne, O.; Hofmann, M.C.J.; Schmidt, M.; Saito, T.; Saido, T.C.; Gurke, R.; Schmidt, D.; Till, U.; Parnham, M.J.; Geisslinger, G.
Zeitschriftenaufsatz
2020Impact of simulated sunlight on the degradation of pendimethalin in surface water in a scale‑up experiment in accordance to OECD TG 309
Hennecke, Dieter; Hassink, Jan; Klein, Judith; Kruse, Mike
Zeitschriftenaufsatz
2020Impact of wastewater-borne nanoparticles of silver and titanium dioxide on the swimming behaviour and biochemical markers of Daphnia magna: An integrated approach
Galhano, Victor; Hartmann, Sarah; Monteiro, Marta S.; Zeumer, Richard; Mozhayeva, Darya; Steinhoff, Benedikt; Müller, Katharina; Prenzel, Kirsten; Kunze, Jan; Kuhnert, Klaus-Dieter; Schönherr, Holger; Engelhard, Carsten; Schlechtriem, Christian; Loureiro, Susana; Soares, Amadeu M.V.M.; Witte, Klaudia; Lopes, Isabel
Zeitschriftenaufsatz
2020Implementation of lipidomics in clinical routine: Can fluoride/citrate blood sampling tubes improve preanalytical stability?
Hahnefeld, L.; Gurke, R.; Thomas, D.; Schreiber, Y.; Schäfer, S.M.G.; Trautmann, S.; Snodgrass, I.F.; Kratz, D.; Geisslinger, G.; Ferreiros, N.
Zeitschriftenaufsatz
2020Improved transgenic sexing strains for genetic control of the Australian sheep blow fly Lucilia cuprina using embryo-specific gene promoters
Yan, Y.; Williamson, M.E.; Davis, R.J.; Andere, A.A.; Picard, C.J.; Scott, M.J.
Zeitschriftenaufsatz
2020Improvement in oxidative stability of versatile peroxidase by flow cytometry-based high-throughput screening system
Ilić Đurđić, K.; Ece, S.; Ostafe, R.; Vogel, S.; Schillberg, S.; Fischer, R.; Prodanović, R.
Zeitschriftenaufsatz
2020Improvement of DNA Vector Delivery of DOTAP Lipoplexes by Short-Chain Aminolipids
Buck, J.; Mueller, D.; Mettal, U.; Ackermann, M.; Grisch-Chan, H.M.; Thöny, B.; Zumbuehl, A.; Huwyler, J.; Witzigmann, D.
Zeitschriftenaufsatz
2020In-vitro safety and off-target profile of the anti-parasitic arylmethylaminosteroid 1o
Blum, L.; Gul, S.; Ulshöfer, T.; Henke, M.; Krieg, R.; Berneburg, I.; Thomas, D.; Trautmann, S.; Kurz, J.; Geyer, J.; Geisslinger, G.; Becker, K.; Parnham, M.J.; Schiffmann, S.
Zeitschriftenaufsatz
2020Incretin combination therapy for the treatment of non-alcoholic steatohepatitis
Kannt, A.; Madsen, A.N.; Kammermeier, C.; Elvert, R.; Klöckener, T.; Bossart, M.; Haack, T.; Evers, A.; Lorenz, K.; Hennerici, W.; Rocher, C.; Böcskei, Z.; Guillemot, J.-C.; Mikol, V.; Pattou, F.; Staels, B.; Wagner, M.
Zeitschriftenaufsatz
2020Individual therapeutic DAS28-dcrit responses differentiate between effectiveness of rheumatoid arthritis therapies and reflect patient-reported outcomes
Koehm, M.; McIntosh, M.J.; Hofmann, M.W.; Abraham, V.; Gabay, C.; Choy, E.H.; Kavanaugh, A.; Burkhardt, H.; Behrens, F.
Zeitschriftenaufsatz
2020Industriebeispiele und Anwendungsbereiche
Schwarz, Thomas; Gürtler, Christoph; Müller, Torsten; Mihalcea, Christophe; Burton, Freya; Conrado, Robert; Simpson, Sean; Maru, Biniam T; Munasinghe, Pradeep C; Jones, Shawn W.; Tracy, Bryan P.; Machielsen, Ronnie; Gordon, Ross; Pant, Deepak; Bulut, Metin; Wever, Helen de; Kensy, Frank; Verseck, Stefan; Janke, Christian
Aufsatz in Buch
2020Influence of glycosphingolipids on cancer cell energy metabolism
Schömel, N.; Geisslinger, G.; Wegner, M.-S.
Zeitschriftenaufsatz
2020Influence of soil on the uptake of perfluoroalkyl acids by lettuce: A comparison between a hydroponic study and a field study
Felizeter, S.; Jürling, H.; Kotthoff, M.; Voogt, P. de; McLachlan, M.S.
Zeitschriftenaufsatz
2020Inhibition of histone acetylation and deacetylation enzymes affects longevity, development, and fecundity in the pea aphid (Acyrthosiphon pisum)
Kirfel, P.; Skaljac, M.; Grotmann, J.; Kessel, T.; Seip, M.; Michaelis, K.; Vilcinskas, A.
Zeitschriftenaufsatz
2020Innovative Imaging Technique for Visualization of Vascularization and Established Methods for Detection of Musculoskeletal Inflammation in Psoriasis Patients
Köhm, M.; Zerweck, L.; Ngyuen, P.-H.; Burkhardt, H.; Behrens, F.
Zeitschriftenaufsatz
2020Innovative Optical-Sensing Technology for the Online Fouling Characterization of Silicon Carbide Membranes during the Treatment of Oily Water
Ebrahimi, M.; Schmidt, A.A.; Kaplan, C.; Schmitz, O.; Czermak, P.
Zeitschriftenaufsatz
2020The insect antimicrobial peptide cecropin A disrupts uropathogenic Escherichia coli biofilms
Kalsy, M.; Tonk, M.; Hardt, M.; Dobrindt, U.; Zdybicka-Barabas, A.; Cytrynska, M.; Vilcinskas, A.; Mukherjee, K.
Zeitschriftenaufsatz
2020Insect Biotechnology. Insects as a Resource
Vilcinskas, Andreas
Aufsatz in Buch
2020Insektizide in Böden unterschiedlicher Bewirtschaftung
Leisner, Jörg; Guhl, Barbara; Hindersmann, Benjamin; Göckener, Bernd
Zeitschriftenaufsatz
2020Interfacing human induced pluripotent stem cell-derived neurons with designed nanowire arrays as a future platform for medical applications
Harberts, J.; Haferkamp, U.; Haugg, S.; Fendler, C.; Lam, D.; Zierold, R.; Pless, O.; Blick, R.H.
Zeitschriftenaufsatz
2020Intravenous Bone Marrow Mononuclear Cells Transplantation in Aged Mice Increases Transcription of Glucose Transporter 1 and Na+/K+-ATPase at Hippocampus Followed by Restored Neurological Functions
Takeuchi, Y.; Okinaka, Y.; Ogawa, Y.; Kikuchi-Taura, A.; Kataoka, Y.; Gul, S.; Claussen, C.; Boltze, J.; Taguchi, A.
Zeitschriftenaufsatz
2020Investigation of Dissolution Performance of Hard Gelatin Capsule Products Using Various Sinkers
Mansuroglu, Y.; Dressman, J.
Zeitschriftenaufsatz
2020The iron load of lipocalin-2 (LCN-2) defines its pro-tumour function in clear-cell renal cell carcinoma
Rehwald, C.; Schnetz, M.; Urbschat, A.; Mertens, C.; Meier, J.K.; Bauer, R.; Baer, P.; Winslow, S.; Roos, F.C.; Zwicker, K.; Huard, A.; Weigert, A.; Brüne, B.; Jung, M.
Zeitschriftenaufsatz
2020l-Thyroxin and the Nonclassical Thyroid Hormone TETRAC are Potent Activators of PPARγ
Gellrich, L.; Heitel, P.; Heering, J.; Kilu, W.; Pollinger, J.; Goebel, T.; Kahnt, A.; Arifi, S.; Pogoda, W.; Paulke, A.; Steinhilber, D.; Proschak, E.; Wurglics, M.; Schubert-Zsilavecz, M.; Chaikuad, A.; Knapp, S.; Bischoff, I.; Fürst, R.; Merk, D.
Zeitschriftenaufsatz
2020Larvae of the clothing moth tineola bisselliella maintain gut bacteria that secrete enzyme cocktails to facilitate the digestion of keratin
Vilcinskas, A.; Schwabe, M.; Brinkrolf, K.; Plarre, R.; Wielsch, N.; Vogel, H.
Zeitschriftenaufsatz
2020LC-MS analysis of the degradation products of a sprayable, biodegradable poly(ester-urethane-urea)
Borrowman, C.K.; Bücking, M.; Göckener, B.; Adhikari, R.; Saito, K.; Patti, A.F.
Zeitschriftenaufsatz
2020Lead Optimization of Phthalazinone Phosphodiesterase Inhibitors as Novel Antitrypanosomal Compounds
Salado, I.G.; Singh, A.K.; Moreno-Cinos, C.; Sakaine, G.; Siderius, M.; Veken, P. Van Der; Matheeussen, A.; Meer, T. Van Der; Sadek, P.; Gul, S.; Maes, L.; Sterk, G.-J.; Leurs, R.; Brown, D.; Augustyns, K.
Zeitschriftenaufsatz
2020Lipid Mediator Profiles Predict Response to Therapy with an Oral Frankincense Extract in Relapsing-Remitting Multiple Sclerosis
Stürner, K.H.; Werz, O.; Koeberle, A.; Otto, M.; Pless, O.; Leypoldt, F.; Paul, F.; Heesen, C.
Zeitschriftenaufsatz
2020The Lipid Receptor G2A (GPR132) Mediates Macrophage Migration in Nerve Injury-Induced Neuropathic Pain
Osthues, T.; Zimmer, B.; Rimola, V.; Klann, K.; Schilling, K.; Mathoor, P.; Angioni, C.; Weigert, A.; Geisslinger, G.; Münch, C.; Scholich, K.; Sisignano, M.
Zeitschriftenaufsatz
2020Local fixation of antibiotics with fibrin spray on soft tissues: Experimental study on the relevance of the application techniques
Verboket, R.; Marzi, I.; Fleck, S.C.; Frank, J.; Janko, M.
Zeitschriftenaufsatz
2020Long-term stimulation of toll-like receptor-2 and -4 upregulates 5-LO and 15-LO-2 expression thereby inducing a lipid mediator shift in human monocyte-derived macrophages
Ebert, R.; Cumbana, R.; Lehmann, C.; Kutzner, L.; Toewe, A.; Ferreirós, N.; Parnham, M.J.; Schebb, N.H.; Steinhilber, D.; Kahnt, A.S.
Zeitschriftenaufsatz
2020Lymphocyte predominant cells detect Moraxella catarrhalis-derived antigens in nodular lymphocyte-predominant Hodgkin lymphoma
Thurner, L.; Hartmann, S.; Fadle, N.; Regitz, E.; Kemele, M.; Kim, Y.-J.; Bohle, R.M.; Nimmesgern, A.; Müller, L. von; Kempf, V.A.J.; Weniger, M.A.; Neumann, F.; Schneider, N.; Vornanen, M.; Sundström, C.; Leval, L. de; Engert, A.; Eichenauer, D.A.; Küppers, R.; Preuss, K.-D.; Hansmann, M.-L.; Pfreundschuh, M.
Zeitschriftenaufsatz
2020Lysine acetyltransferase p300/cbp plays an important role in reproduction, embryogenesis and longevity of the pea aphid acyrthosiphon pisum
Kirfel, P.; Vilcinskas, A.; Skaljac, M.
Zeitschriftenaufsatz
2020Machine-learned association of next-generation sequencing-derived variants in thermosensitive ion channels genes with human thermal pain sensitivity phenotypes
Lötsch, J.; Kringel, D.; Geisslinger, G.; Oertel, B.G.; Resch, E.; Malkusch, S.
Zeitschriftenaufsatz
2020Machine-learned identification of psychological subgroups with relation to pain interference in patients after breast cancer treatments
Sipilä, R.; Kalso, E.; Lötsch, J.
Zeitschriftenaufsatz
2020Machine-learning-based knowledge discovery in rheumatoid arthritis-related registry data to identify predictors of persistent pain
Lötsch, J.; Alfredsson, L.; Lampa, J.
Zeitschriftenaufsatz
2020Machine-learning-derived rules set excludes risk of Parkinson’s disease in patients with olfactory or gustatory symptoms with high accuracy
Lötsch, J.; Haehner, A.; Hummel, T.
Zeitschriftenaufsatz
2020Macrophage-derived iron-bound lipocalin-2 correlates with renal recovery markers following sepsis-induced kidney damage
Mertens, C.; Kuchler, L.; Sola, A.; Guiteras, R.; Grein, S.; Brüne, B.; Knethen, A. von; Jung, M.
Zeitschriftenaufsatz
2020The Major Floral Promoter NtFT5 in Tobacco (Nicotiana tabacum) is a Promising Target for Crop Improvement
Schmidt, F.J.; Zimmermann, M.M.; Wiedmann, D.R.; Lichtenauer, S.; Grundmann, L.; Muth, J.; Twyman, R.M.; Prüfer, D.; Noll, G.A.
Zeitschriftenaufsatz
2020Measuring pH and Buffer Capacity in Fluids Aspirated from the Fasted Upper Gastrointestinal Tract of Healthy Adults
Litou, C.; Psachoulias, D.; Vertzoni, M.; Dressman, J.; Reppas, C.
Zeitschriftenaufsatz
2020Membrane-based steric exclusion chromatography for the purification of a recombinant baculovirus and its application for cell therapy
Lothert, K.; Sprick, G.; Beyer, F.; Lauria, G.; Czermak, P.; Wolff, M.W.
Zeitschriftenaufsatz
2020MicroRNAs as emerging regulators of signaling in the tumor microenvironment
Syed, S.N.; Brüne, B.
Zeitschriftenaufsatz
2020MicroRNAs regulate innate immunity against uropathogenic and commensal-like Escherichia coli infections in the surrogate insect model Galleria mellonella
Mukherjee, K.; Amsel, D.; Kalsy, M.; Billion, A.; Dobrindt, U.; Vilcinskas, A.
Zeitschriftenaufsatz
2020Molecular farming - the slope of enlightenment
Fischer, R.; Buyel, J.F.
Zeitschriftenaufsatz
2020Molecular Networking-Guided Discovery and Characterization of Stechlisins, a Group of Cyclic Lipopeptides from a Pseudomonas sp.
Marner, M.; Patras, M.A.; Kurz, M.; Zubeil, F.; Förster, F.; Schuler, S.; Bauer, A.; Hammann, P.; Vilcinskas, A.; Schaberle, T.F.; Glaeser, J.
Zeitschriftenaufsatz
2020Natural antiviral compound silvestrol modulates human monocyte-derived macrophages and dendritic cells
Blum, L.; Geisslinger, G.; Parnham, M.J.; Grünweller, A.; Schiffmann, S.
Zeitschriftenaufsatz
2020Neuropathic and cAMP-induced pain behavior is ameliorated in mice lacking CNGB1
Kallenborn-Gerhardt, W.; Metzner, K.; Lu, R.; Petersen, J.; Kuth, M.S.; Heine, S.; Drees, O.; Paul, M.; Becirovic, E.; Kennel, L.; Flauaus, C.; Gross, T.; Wack, G.; Hohmann, S.W.; Nemirovski, D.; Del Turco, D.; Biel, M.; Geisslinger, G.; Michalakis, S.; Schmidtko, A.
Zeitschriftenaufsatz
2020A new citrinin derivative from the Indonesian Marine Sponge-Associated Fungus Penicillium citrinum
Sabdaningsih, A.; Liu, Y.; Mettal, U.; Heep, J.; Riyanti; Wang, L.; Cristianawati, O.; Nuryadi, H.; Sibero, M.T.; Marner, M.; Radjasa, O.K.; Sabdono, A.; Trianto, A.; Schäberle, T.F.
Zeitschriftenaufsatz
2020Next-Generation Sequencing of T and B Cell Receptor Repertoires from COVID-19 Patients Showed Signatures Associated with Severity of Disease
Schultheiß, C.; Paschold, L.; Simnica, D.; Mohme, M.; Willscher, E.; Wenserski, L. von; Scholz, R.; Wieters, I.; Dahlke, C.; Tolosa, E.; Sedding, D.G.; Ciesek, S.; Addo, M.; Binder, M.
Zeitschriftenaufsatz
2020A non-parametric effect-size measure capturing changes in central tendency and data distribution shape
Lötsch, J.; Ultsch, A.
Zeitschriftenaufsatz
2020The NORMAN Association and the European Partnership for Chemicals Risk Assessment (PARC): Let’s cooperate!
Dulio, V.; Koschorreck, J.; Bavel, B. van; Brink, P. van den; Hollender, J.; Munthe, J.; Schlabach, M.; Aalizadeh, R.; Agerstrand, M.; Ahrens, L.; Allan, I.; Alygizakis, N.; Barcelo, D.; Bohlin-Nizzetto, P.; Boutroup, S.; Brack, W.; Bressy, A.; Christensen, J.H.; Cirka, L.; Covaci, A.; Derksen, A.; Deviller, G.; Dingemans, M.M.L.; Engwall, M.; Fatta-Kassinos, D.; Gago-Ferrero, P.; Hernández, F.; Herzke, D.; Hilscherová, K.; Hollert, H.; Junghans, M.; Kasprzyk-Hordern, B.; Keiter, S.; Kools, S.A.E.; Kruve, A.; Lambropoulou, D.; Lamoree, M.; Leonards, P.; Lopez, B.; López de Alda, M.; Lundy, L.; Makovinská, J.; Marigómez, I.; Martin, J.W.; McHugh, B.; Miège, C.; O’Toole, S.; Perkola, N.; Polesello, S.; Posthuma, L.; Rodriguez-Mozaz, S.; Roessink, I.; Rostkowski, P.; Ruedel, H.; Samanipour, S.; Schulze, T.; Schymanski, E.L.; Sengl, M.; Tarábek, P.; Ten Hulscher, D.; Thomaidis, N.; Togola, A.; Valsecchi, S.; Leeuwen, S. van; Ohe, P. von der; Vorkamp, K.; Vrana, B.; Slobodnik, J.
Zeitschriftenaufsatz
2020The omega-3 lipid 17,18-EEQ sensitizes TRPV1 and TRPA1 in sensory neurons through the prostacyclin receptor (IP)
Schäfer, S.M.G.; Sendetski, M.; Angioni, C.; Nüsing, R.; Geisslinger, G.; Scholich, K.; Sisignano, M.
Zeitschriftenaufsatz
2020Opportunities to debottleneck the downstream processing of the oncolytic measles virus
Loewe, D.; Dieken, H.; Grein, T.A.; Weidner, T.; Salzig, D.; Czermak, P.
Zeitschriftenaufsatz
2020Optimizing product quality in molecular farming
Schiermeyer, Andreas
Zeitschriftenaufsatz
2020The orphan nuclear receptor Nurr1 is responsive to non-steroidal anti-inflammatory drugs
Willems, S.; Kilu, W.; Ni, X.; Chaikuad, A.; Knapp, S.; Heering, J.; Merk, D.
Zeitschriftenaufsatz
2020Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity
Shin, D.; Mukherjee, R.; Grewe, D.; Bojkova, D.; Baek, K.; Bhattacharya, A.; Schulz, L.; Widera, M.; Mehdipour, A.R.; Tascher, G.; Geurink, P.P.; Wilhelm, A.; Heden van Noort, G.J. van der; Ovaa, H.; Müller, S.; Knobeloch, K.-P.; Rajalingam, K.; Schulman, B.A.; Cinatl, J.; Hummer, G.; Ciesek, S.; Dikic, I.
Zeitschriftenaufsatz
2020Parallel evolution of complex centipede venoms
Jenner, R.; Reumont, B. von; Campbell, L.; Undheim, E.
Zeitschriftenaufsatz, Konferenzbeitrag
2020Per- and polyfluoroalkyl substances in the German environment
Kotthoff, M.; Fliedner, A.; Rüdel, H.; Göckener, B.; Bücking, M.; Biegel-Engler, A.; Koschorreck, J.
Zeitschriftenaufsatz
2020Persistent, mobile and toxic substances in the environment: A spotlight on current research and regulatory activities
Rüdel, Heinz; Körner, Wolfgang; Letzel, Thomas; Neumann, Michael; Nödler, Karsten; Reemtsma, Thorsten
Zeitschriftenaufsatz
2020Photohormones Enable Optical Control of the Peroxisome Proliferator-Activated Receptor γ (PPARγ)
Hinnah, K.; Willems, S.; Morstein, J.; Heering, J.; Hartrampf, F.W.W.; Broichhagen, J.; Leippe, P.; Merk, D.; Trauner, D.
Zeitschriftenaufsatz
2020Phylotranscriptomic evidence for pervasive ancient hybridization among Old World salamanders
Rancilhac, L.; Irisarri, I.; Angelini, C.; Arntzen, J.W.; Babik, W.; Bossuyt, F.; Künzel, S.; Lüddecke, T.; Pasmans, F.; Sanchez, E.; Weisrock, D.; Veith, M.; Wielstra, B.; Steinfartz, S.; Hofreiter, M.; Philippe, H.; Vences, M.
Zeitschriftenaufsatz
2020Physiologically based pharmacokinetic model outputs depend on dissolution data and their input
Klumpp, L.; Dressman, J.
Zeitschriftenaufsatz
2020A physiologically-based nanocarrier biopharmaceutics model to reverse-engineer the in vivo drug release
Nagpal, S.; Braner, S.; Modh, H.; Tan, A.X.X.; Mast, M.-P.; Chichakly, K.; Albrecht, V.; Wacker, M.G.
Zeitschriftenaufsatz
2020Potential Applications of Plant Biotechnology against SARS-CoV-2
Capell, T.; Twyman, R.M.; Armario-Najera, V.; Ma, J.K.-C.; Schillberg, S.; Christou, P.
Zeitschriftenaufsatz
2020Predicting human pharmacokinetics of liposomal temoporfin using a hybrid in silico model
Jablonka, L.; Ashtikar, M.; Gao, G.F.; Thurn, M.; Modh, H.; Wang, J.-W.; Preuß, A.; Scheglmann, D.; Albrecht, V.; Röder, B.; Wacker, M.G.
Zeitschriftenaufsatz
2020Production and purification of fructo-oligosaccharides using an enzyme membrane bioreactor and subsequent fermentation with probiotic Bacillus coagulans
Fan, R.; Burghardt, J.P.; Prell, F.; Zorn, H.; Czermak, P.
Zeitschriftenaufsatz
2020The production of isoprene from cellulose using recombinant Clostridium cellulolyticum strains expressing isoprene synthase
Janke, C.; Gaida, S.; Jennewein, S.
Zeitschriftenaufsatz
2020Progranulin deficiency confers resistance to autoimmune encephalomyelitis in mice
Schmitz, K.; Wilken-Schmitz, A.; Vasic, V.; Brunkhorst, R.; Schmidt, M.; Tegeder, I.
Zeitschriftenaufsatz
2020Proline-Rich Antimicrobial Peptides in Medicinal Maggots of Lucilia sericata Interact with Bacterial DnaK but do not Inhibit Protein Synthesis
Cytrynska, M.; Rahnamaeian, M.; Zdybicka-Barabas, A.; Dobslaff, K.; Züchner, T.; Sacheau, G.; Innis, C.A.; Vilcinskas, A.
Zeitschriftenaufsatz
2020Proteo-Transcriptomic Analysis Identifies Potential Novel Toxins Secreted by the Predatory, Prey-Piercing Ribbon Worm Amphiporus lactifloreus
Reumont, B.M. von; Lüddecke, T.; Timm, T.; Lochnit, G.; Vilcinskas, A.; Döhren, J. von; Nilsson, M.A.
Zeitschriftenaufsatz
2020Proteomics as an alternative approach for hazard characterization and the identification of specific chemical targets: Elucidation of potential biomarkers for differentiating endocrine disruption from hepatotoxicity
Ayobahan, Steve Uwa
: Hollert, Henner; Schäfers, Christoph; Schäffer, Andreas
Dissertation
2020Quintaquinone, a Merosesquiterpene from the Yellow Sponge Verongula cf. rigida Esper
Jiso, A.; Kittiwisut, S.; Chantakul, R.; Yuenyongsawad, S.; Putchakarn, S.; Schäberle, T.F.; Temkitthaworn, P.; Ingkaninan, K.; Chaithirayanon, K.; Plubrukarn, A.
Zeitschriftenaufsatz
2020Rab27a Contributes to the Processing of Inflammatory Pain in Mice
Gross, T.; Wack, G.; Syhr, K.M.J.; Tolmachova, T.; Seabra, M.C.; Geisslinger, G.; Niederberger, E.; Schmidtko, A.; Kallenborn-Gerhardt, W.
Zeitschriftenaufsatz
2020The Radiokitchen: Understanding chemical reactions during food processing
Bücking, Mark; Göckener, Bernd
Zeitschriftenaufsatz
2020Random forests followed by computed ABC analysis as a feature selection method for machine learning in biomedical data
Lötsch, J.; Ultsch, A.
Konferenzbeitrag
2020Rare Loss-of-Function Mutation in SERPINA3 in Generalized Pustular Psoriasis
Frey, S.; Sticht, H.; Wilsmann-Theis, D.; Gerschütz, A.; Wolf, K.; Löhr, S.; Haskamp, S.; Frey, B.; Hahn, M.; Ekici, A.B.; Uebe, S.; Thiel, C.; Reis, A.; Burkhardt, H.; Behrens, F.; Köhm, M.; Rech, J.; Schett, G.; Assmann, G.; Kingo, K.; Koks, S.; Mössner, R.; Prinz, J.C.; Oji, V.; Schulz, P.; Muñoz, L.E.; Kremer, A.E.; Wenzel, J.; Hüffmeier, U.
Zeitschriftenaufsatz
2020Recent advances in Salamandra skin poison research
Lüddecke, T.
Zeitschriftenaufsatz, Konferenzbeitrag
2020Redox Regulation of PPARγ in Polarized Macrophages
Trümper, V.; Wittig, I.; Heidler, J.; Richter, F.; Brüne, B.; Knethen, A. von
Zeitschriftenaufsatz
2020Relevance of instruments for measurements of quality of life in the AMNOG context
Schneider, N.
Aufsatz in Buch
2020Removal of Small-Molecular Byproducts from Crude Fructo-Oligosaccharide Preparations by Fermentation Using the Endospore-Forming Probiotic Bacillus coagulans
Fan, R.; Burghardt, J.P.; Xiong, T.; Czermak, P.
Zeitschriftenaufsatz
2020Reprograming of epigenetic mechanisms controlling host insect immunity and development in response to egg-laying by a parasitoid wasp
Özbek, R.; Mukherjee, K.; Uçkan, F.; Vilcinskas, A.
Zeitschriftenaufsatz
2020Retraction notice to "Differentiation of human iPSCs into VSMCs and generation of VSMC-derived calcifying vascular cells" [Stem Cell Res. 31 (2018) 62-70]
Trillhaase, A.; Haferkamp, U.; Rangnau, A.; Märtens, M.; Schmidt, B.; Trilck, M.; Seibler, P.; Aherrahrou, R.; Erdmann, J.; Aherrahrou, Z.
Zeitschriftenaufsatz
2020Retrospective analysis of cyclic volatile methylsiloxanes in archived German fish samples covering a period of two decades
Radermacher, Georg; Rüdel, Heinz; Wesch, Charlotte; Böhnhardt, Anna; Koschorreck, Jan
Zeitschriftenaufsatz
2020Robot Cookies - Plant Cell Packs as an Automated High-Throughput Screening Platform Based on Transient Expression
Gengenbach, B.B.; Opdensteinen, P.; Buyel, J.F.
Zeitschriftenaufsatz
2020Robustheitsuntersuchung zur Resorptionsverfügbarkeit von Schadstoffen in Böden. Abschlussbericht
Barkowski, Dietmar; Krüger, Gerald; Machtolf, Monika; Derz, Kerstin; Küchler, Frank
Bericht
2020S1P d20:1, an endogenous modulator of S1P d18:1/S1P2-dependent signaling
Vutukuri, R.; Koch, A.; Trautmann, S.; Schreiber, Y.; Thomas, D.; Mayser, F.; Meyer zu Heringdorf, D.; Pfeilschifter, J.; Pfeilschifter, W.; Brunkhorst, R.
Zeitschriftenaufsatz
2020S1PR4 ablation reduces tumor growth and improves chemotherapy via CD8+ T cell expansion
Olesch, C.; Sirait-Fischer, E.; Berkefeld, M.; Fink, A.F.; Susen, R.M.; Ritter, B.; Michels, B.E.; Steinhilber, D.; Greten, F.R.; Savai, R.; Takeda, K.; Brüne, B.; Weigert, A.
Zeitschriftenaufsatz
2020S1PR4-dependent CCL2 production promotes macrophage recruitment in a murine psoriasis model
Schuster, C.; Huard, A.; Sirait-Fischer, E.; Dillmann, C.; Brüne, B.; Weigert, A.
Zeitschriftenaufsatz
2020Saturation mutagenesis to improve the degradation of azo dyes by versatile peroxidase and application in form of VP-coated yeast cell walls
Ilić Đurđić, K.; Ostafe, R.; Đurđević Đelmaš, A.; Popović, N.; Schillberg, S.; Fischer, R.; Prodanovic, R.
Zeitschriftenaufsatz
2020A scalable downstream process for the purification of the cell culture-derived Orf virus for human or veterinary applications
Lothert, K.; Pagallies, F.; Eilts, F.; Sivanesapillai, A.; Hardt, M.; Moebus, A.; Feger, T.; Amann, R.; Wolff, M.W.
Zeitschriftenaufsatz
2020Schmerzmodelle und klinische Schmerzforschung sind kein Widerspruch
Lötsch, J.; Geisslinger, G.; Walter, C.
Zeitschriftenaufsatz
2020Schulung von Medizinischen Fachangestellten bei hausärztlichen Forschungsprojekten. Wissensgewinn und Unterschiede zwischen einer Präsenzschulung und dem Selbststudium eines Schulungshandbuches
Mergenthal, K.; Schulz-Rothe, S.; Siebenhofer, A.; Gerlach, F.M.; Rossmanith, T.; Petersen, J.J.
Zeitschriftenaufsatz
2020Seasonal phenotype-specific expression of microRNAs during metamorphosis in the European map butterfly Araschnia levana
Mukherjee, K.; Baudach, A.; Vogel, H.; Vilcinskas, A.
Zeitschriftenaufsatz
2020Seasonal variability in metal and metalloid burdens of mussels: Using data from the German Environmental Specimen Bank to evaluate implications for long-term mussel monitoring programs
Knopf, Burkhard; Fliedner, Annette; Radermacher, Georg; Rüdel, Heinz; Paulus, Martin; Pirntke, Ulrike; Koschorreck, Jan
Zeitschriftenaufsatz
2020Secukinumab versus adalimumab for treatment of active psoriatic arthritis (EXCEED): A double-blind, parallel-group, randomised, active-controlled, phase 3b trial
McInnes, I.B.; Behrens, F.; Mease, P.J.; Kavanaugh, A.; Ritchlin, C.; Nash, P.; Masmitja, J.G.; Goupille, P.; Korotaeva, T.; Gottlieb, A.B.; Martin, R.; Ding, K.; Pellet, P.; Mpofu, S.; Pricop, L.
Zeitschriftenaufsatz
2020Selection and application of trophic magnification factors for priority substances to normalize freshwater fish monitoring data under the European Water Framework Directive: A case study
Rüdel, Heinz; Kosfeld, Verena; Fliedner, Annette; Radermacher, Georg; Schlechtriem, Christian; Duffek, Anja; Rauert, Caren; Koschorreck, Jan
Zeitschriftenaufsatz
2020Selection of chromatographic methods for the purification of cell culture-derived Orf virus for its application as a vaccine or viral vector
Lothert, K.; Pagallies, F.; Feger, T.; Amann, R.; Wolff, M.W.
Zeitschriftenaufsatz
2020A Selective Modulator of Peroxisome Proliferator-Activated Receptor γ with an Unprecedented Binding Mode
Hanke, T.; Cheung, S.-Y.; Kilu, W.; Heering, J.; Ni, X.; Planz, V.; Schierle, S.; Faudone, G.; Friedrich, M.; Wanior, M.; Werz, O.; Windbergs, M.; Proschak, E.; Schubert-Zsilavecz, M.; Chaikuad, A.; Knapp, S.; Merk, D.
Zeitschriftenaufsatz
2020Sensitive aflatoxin B1 detection using nanoparticle-based competitive magnetic immunodetection
Pietschmann, J.; Spiegel, H.; Krause, H.-J.; Schillberg, S.; Schröper, F.
Zeitschriftenaufsatz
2020A sensitive in vitro performance assay reveals the in vivo drug release mechanisms of long-acting medroxyprogesterone acetate microparticles
Gao, G.F.; Thurn, M.; Wendt, B.; Parnham, M.J.; Wacker, M.G.
Zeitschriftenaufsatz
2020Short-term variability of the human serum metabolome depending on nutritional and metabolic health status
Agueusop, I.; Musholt, P.B.; Klaus, B.; Hightower, K.; Kannt, A.
Zeitschriftenaufsatz
2020Silencing of the DNA methyltransferase 1 associated protein 1 (DMAP1) gene in the invasive ladybird Harmonia axyridis implies a role of the DNA methyltransferase 1-DMAP1 complex in female fecundity
Gegner, J.; Gegner, T.; Vogel, H.; Vilcinskas, A.
Zeitschriftenaufsatz
2020The Specific IKKε/TBK1 Inhibitor Amlexanox Suppresses Human Melanoma by the Inhibition of Autophagy, NF-κB and MAP Kinase Pathways
Möller, M.; Wasel, J.; Schmetzer, J.; Weiß, U.; Meissner, M.; Schiffmann, S.; Weigert, A.; Möser, C.V.; Niederberger, E.
Zeitschriftenaufsatz
2020Sphingosine kinases are involved in macrophage NLRP3 inflammasome transcriptional induction
Syed, S.N.; Weigert, A.; Brüne, B.
Zeitschriftenaufsatz
2020Suitability of the z-Factor for Dissolution Simulation of Solid Oral Dosage Forms
Hofsäss, M.A.; Dressman, J.
Zeitschriftenaufsatz
2020Supplementation of sulfur-containing amino acids or essential amino acids does not reverse the hepatic lipid-lowering effect of a protein-rich insect meal in obese zucker rats
Meyer, S.; Schäfer, L.; Röhrig, J.; Maheshwari, G.; Most, E.; Zorn, H.; Ringseis, R.; Eder, K.; Gessner, D.K.
Zeitschriftenaufsatz
2020Sustained improvement in work outcomes in employed patients with rheumatoid arthritis during 2 years of adalimumab therapy: An observational cohort study
Behrens, F.; Tony, H.-P.; Koehm, M.; Schwaneck, E.C.; Gnann, H.; Greger, G.; Burkhardt, H.; Schmalzing, M.
Zeitschriftenaufsatz
2020A systematic comparison of chloroplast genome assembly tools
Freudenthal, J.A.; Pfaff, S.; Terhoeven, N.; Korte, A.; Ankenbrand, M.J.; Förster, F.
Zeitschriftenaufsatz
2020Systematic Discovery of Short Linear Motifs Decodes Calcineurin Phosphatase Signaling
Wigington, C.P.; Roy, J.; Damle, N.P.; Yadav, V.K.; Blikstad, C.; Resch, E.; Wong, C.J.; Mackay, D.R.; Wang, J.T.; Krystkowiak, I.; Bradburn, D.A.; Tsekitsidou, E.; Hong, S.H.; Kaderali, M.A.; Xu, S.-L.; Stearns, T.; Gingras, A.-C.; Ullman, K.S.; Ivarsson, Y.; Davey, N.E.; Cyert, M.S.
Zeitschriftenaufsatz
2020Tenebrio molitor larvae meal affects the cecal microbiota of growing pigs
Meyer, S.; Gessner, D.K.; Maheshwari, G.; Röhrig, J.; Friedhoff, T.; Most, E.; Zorn, H.; Ringseis, R.; Eder, K.
Zeitschriftenaufsatz
2020Terpenoids from the Coral-Derived Fungus Trichoderma harzianum (XS-20090075) Induced by Chemical Epigenetic Manipulation
Shi, T.; Shao, C.-L.; Liu, Y.; Zhao, D.-L.; Cao, F.; Fu, X.-M.; Yu, J.-Y.; Wu, J.-S.; Zhang, Z.-K.; Wang, C.-Y.
Zeitschriftenaufsatz
2020Testing the bioaccumulation of manufactured nanomaterials in the freshwater bivalve Corbicula fluminea using a new test method
Kühr, Sebastian; Meisterjahn, Boris; Schröder, Nicola; Knopf, Burkhard; Völker, Doris; Schwirn, Kathrin; Schlechtriem, Christian
Zeitschriftenaufsatz
2020Therapie der Psoriasisarthritis
Köhm, M.; Behrens, F.
Zeitschriftenaufsatz
2020Therapiestrategien der Psoriasisarthritis
Köhm, M.; Burkhardt, H.; Behrens, F.
Zeitschriftenaufsatz
2020A tiered high-throughput screening approach for evaluation of estrogen and androgen receptor modulation by environmentally relevant bisphenol A substitutes
Keminer, Oliver; Teigeler, Matthias; Kohler, Manfred; Wenzel, Andrea; Arning, Jürgen; Kaßner, Franziska; Windshügel, Björn; Eilebrecht, Elke
Zeitschriftenaufsatz
2020TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells
Bestle, D.; Heindl, M.R.; Limburg, H.; Van Lam van, T.; Pilgram, O.; Moulton, H.; Stein, D.A.; Hardes, K.; Eickmann, M.; Dolnik, O.; Rohde, C.; Klenk, H.-D.; Garten, W.; Steinmetzer, T.; Böttcher-Friebertshäuser, E.
Zeitschriftenaufsatz
2020Tracing neglected venom systems: Prediction of the industrial potential by a multi-disciplinary data network
Kirchhoff, K.N.; Vilcinskas, A.; Wilke, T.
Zeitschriftenaufsatz, Konferenzbeitrag
2020Transfer of Per- and Polyfluoroalkyl Substances (PFAS) from Feed into the Eggs of Laying Hens. Pt.1: Analytical Results Including a Modified Total Oxidizable Precursor Assay
Göckener, Bernd; Eichhorn, Maria; Lämmer, René; Kotthoff, Matthias; Kowalczyk, Janine; Numata, Jorge; Schafft, Helmut; Lahrssen-Wiederholt, Monika; Bücking, Mark
Zeitschriftenaufsatz
2020Transfer of Per- and Polyfluoroalkyl Substances (PFAS) from Feed into the Eggs of Laying Hens. Pt.2: Toxicokinetic Results Including the Role of Precursors
Kowalczyk, Janine; Göckener, Bernd; Eichhorn, Maria; Kotthoff, Matthias; Bücking, Mark; Schafft, Helmut; Lahrssen-Wiederholt, Monika; Numata, Jorge
Zeitschriftenaufsatz
2020Translational tarantula phylogenomics: Evolution of theraphosid spiders and their defensive arsenal with implications for venom bioprospecting
Lüddecke, T.
Zeitschriftenaufsatz, Konferenzbeitrag
2020Tumors provoke inflammation and perineural microlesions at adjacent peripheral nerves
Cohnen, Jennifer; Kornstädt, Lisa; Hahnefeld, Lisa; Ferreiros, Nerea; Pierre, Sandra; Koehl, Ulrike; Deller, Thomas; Geisslinger, Gerd; Scholich, Klaus
Zeitschriftenaufsatz
2020Turbidimetry and dielectric spectroscopy as process analytical technologies for mammalian and insect cell cultures
Käßer, L.; Zitzmann, J.; Grein, T.; Weidner, T.; Salzig, D.; Czermak, P.
Aufsatz in Buch
2020UGCG overexpression leads to increased glycolysis and increased oxidative phosphorylation of breast cancer cells
Schömel, N.; Gruber, L.; Alexopoulos, S.J.; Trautmann, S.; Olzomer, E.M.; Byrne, F.L.; Hoehn, K.L.; Gurke, R.; Thomas, D.; Ferreiros, N.; Geisslinger, G.; Wegner, M.-S.
Zeitschriftenaufsatz
2020Die Umweltprobenbank des Bundes - Umwelt- und Humanproben
Weber, T.; Koschorrek, J.; Rüther, M.; Körner, A.; Knopf, B.; Kotthoff, M.; Rüdel, H.; Lermen, D.; Bartel-Steinbach, M.; Göen, T.; Paulus, M.; Klein, R.; Veith, M.; Kolossa-Gehring, M.
Zeitschriftenaufsatz
2020Unraveling the Pharmacological Potential of Lichen Extracts in the Context of Cancer and Inflammation With a Broad Screening Approach
Ingelfinger, R.; Henke, M.; Roser, L.; Ulshöfer, T.; Calchera, A.; Singh, G.; Parnham, M.J.; Geisslinger, G.; Fürst, R.; Schmitt, I.; Schiffmann, S.
Zeitschriftenaufsatz
2020Unravelling the uptake pathway and accumulation of silver from manufactured silver nanoparticles in the freshwater amphipod Hyalella azteca using correlative microscopy
Kühr, Sebastian; Klehm, Jessica; Stehr, Claudia; Menzel, Matthias; Schlechtriem, Christian
Zeitschriftenaufsatz
2020Untersuchungen zur möglichen Freisetzung von Nanopartikeln bei der Ablagerung und bodenbezogenen Anwendung von mineralischen Abfällen. Abschlussbericht
Oischinger, Jürgen; Meiller, Martin; Daschner, Robert; Hennecke, Dieter; Hund-Rinke, Kerstin; Meisterjahn, Boris; Schröder, Nicola
Bericht
2020The use of PBPK/PD to establish clinically relevant dissolution specifications for zolpidem immediate release tablets
Paraiso, R.L.M.; Rose, R.H.; Fotaki, N.; McAllister, M.; Dressman, J.B.
Zeitschriftenaufsatz
2020The venom gland transcriptome of the wasp spider Argiope bruennichi
Lüddecke, T.; Förster, F.; Billion, A.; Reumont, B.M. von; Vilcinskas, A.; Lemke, S.
Zeitschriftenaufsatz, Konferenzbeitrag