Fraunhofer-Gesellschaft

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Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2020An automated and high-throughput-screening compatible pluripotent stem cell-based test platform for developmental and reproductive toxicity assessment of small molecule compounds
Witt, Gesa; Keminer, Oliver; Leu, Jennifer; Tandon, Rashmi; Meiser, Ina; Willing, Anne; Winschel, Ingo; Abt, Jana-Christin; Brändl, Björn; Sébastien, Isabelle; Friese, Manuel A.; Müller, Franz Josef; Neubauer, Julia C.; Claussen, Carsten; Zimmermann, Heiko; Gribbon, Philip; Pless, Ole
Zeitschriftenaufsatz
2020Bicistronic expression and differential localization of proteins in insect cells and Drosophila suzukii using picornaviral 2A peptides
Schwirz, J.; Yan, Y.; Franta, Z.; Schetelig, M.F.
Zeitschriftenaufsatz
2020Bildgebung bei der Psoriasisarthritis und Aspekte der röntgenologischen Progression
Baraliakos, X.; Kleyer, A.; Simon, D.; Köhm, M.; Ohrndorf, S.; Sewerin, P.
Zeitschriftenaufsatz
2020Bioavailability of silver from wastewater and planktonic food borne silver nanoparticles in the rainbow trout Oncorhynchus mykiss
Zeumer, Richard; Hermsen, Lara; Kägi, Ralf; Kühr, Sebastian; Knopf, Burkhard; Schlechtriem, Christian
Zeitschriftenaufsatz
2020Bioconcentration, metabolism and spatial distribution of 14C‐labelled laurate in the freshwater amphipod Hyalella Azteca
Raths, Johannes; Kühr, Sebastian; Schlechtriem, Christian
Zeitschriftenaufsatz
2020Biodegradation testing of volatile hydrophobic chemicals in water-sediment systems - Experimental developments and challenges
Shresta, Prasit; Meisterjahn, Boris; Hughes, Christopher B.; Mayer, Philipp; Birch, Heidi; Hennecke, Dieter
Zeitschriftenaufsatz
2020Biotransformation Changes Bioaccumulation and Toxicity of Diclofenac in Aquatic Organisms
Fu, Qiuguo; Fedrizzi, Davide; Kosfeld, Verena; Schlechtriem, Christian; Ganz, Vera; Derrer, Samuel; Rentsch, Daniel; Hollender, Juliane
Zeitschriftenaufsatz
2020Chemicals of emerging concern in marine specimens of the German Environmental Specimen Bank
Fliedner, Annette; Rüdel, Heinz; Dreyer, Annekatrin; Pirntke, Ulrike; Koschorreck, Jan
Zeitschriftenaufsatz
2020Chronic effects of wastewater-borne silver and titanium dioxide nanoparticles on the rainbow trout (Oncorhynchus mykiss)
Zeumer, Richard; Galhano, Victor; Monteiro, Marta S.; Kühr, Sebastian; Knopf, Burkhard; Meisterjahn, Boris; Soares, Amadeu M.V.M.; Loureiro, Susana; Lopes, Isabel; Schlechtriem, Christian
Zeitschriftenaufsatz
2020Collecting data through high throughput in vitro early toxicity and off-target liability assays to rapidly identify limitations of novel thyromimetics
Runfola, M.; Sestito, S.; Gul, S.; Chiellini, G.; Rapposelli, S.
Zeitschriftenaufsatz
2020Comparative proteome and metabolome analyses of latex-exuding and non-exuding Taraxacum koksaghyz roots provide insights into laticifer biology
Benninghaus, V.A.; Deenen, N. van; Müller, B.; Roelfs, K.-U.; Lassowskat, I.; Finkemeier, I.; Prüfer, D.; Schulze Gronover, C.
Zeitschriftenaufsatz
2020Comprehensive analysis of all evolutionary paths between two divergent PDZ domain specificities
Teyra, J.; Ernst, A.; Singer, A.; Sicheri, F.; Sidhu, S.S.
Zeitschriftenaufsatz
2020Current projection methods-induced biases at subgroup detection for machine-learning based data-analysis of biomedical data
Lötsch, J.; Ultsch, A.
Zeitschriftenaufsatz
2020Data-science-based subgroup analysis of persistent pain during 3 years after breast cancer surgery: A prospective cohort study
Lötsch, J.; Ultsch, A.; Kalso, E.
Zeitschriftenaufsatz
2020Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis
Runfola, M.; Sestito, S.; Bellusci, L.; Pietra, V. la; D'Amore, V.M.; Kowalik, M.A.; Chiellini, G.; Gul, S.; Perra, A.; Columbano, A.; Marinelli, L.; Novellino, E.; Rapposelli, S.
Zeitschriftenaufsatz
2020Detection of biomarkers to differentiate endocrine disruption from hepatotoxicity in zebrafish (Danio rerio) using proteomics
Ayobahan, Steve U.; Eilebrecht, Sebastian; Baumann, Lisa; Teigeler, Matthias; Hollert, Henner; Kalkhof, Stefan; Eilebrecht, Elke; Schäfers, Christoph
Zeitschriftenaufsatz
2020Development of a method to determine the bioaccumulation of manufactured nanomaterials in filtering organisms (Bivalvia). Final Report
Schlechtriem, Christian; Knopf, Burkhard; Kühr, Sebastian; Meisterjahn, Boris; Schröder, Nicola
Bericht
2020Development of a test method for transformation of veterinary pharmaceuticals and biocides in anaerobic liquid manure
Junker, Thomas; Atorf, Cornelia; Berkner, Silvia; Düring, Rolf-Alexander; Hennecke, Dieter; Herrchen, Monika; Konradi, Sabine; Merrettig‑Bruns, Ute; Römbke, Jörg; Wagner, Julia; Weinfurtner, Karlheinz
Zeitschriftenaufsatz
2020Distribution Optimization: An evolutionary algorithm to separate Gaussian mixtures
Lerch, F.; Ultsch, A.; Lötsch, J.
Zeitschriftenaufsatz
2020The disturbed iron phenotype of tumor cells and macrophages in renal cell carcinoma influences tumor growth
Schnetz, M.; Meier, J.K.; Rehwald, C.; Mertens, C.; Urbschat, A.; Tomat, E.; Akam, E.A.; Baer, P.; Roos, F.C.; Brüne, B.; Jung, M.
Zeitschriftenaufsatz
2020Dual Farnesoid X Receptor/Soluble Epoxide Hydrolase Modulators Derived from Zafirlukast
Schierle, S.; Helmstädter, M.; Schmidt, J.; Hartmann, M.; Horz, M.; Kaiser, A.; Weizel, L.; Heitel, P.; Proschak, A.; Hernandez-Olmos, V.; Proschak, E.; Merk, D.
Zeitschriftenaufsatz
2020Establishing virtual bioequivalence and clinically relevant specifications using in vitro biorelevant dissolution testing and physiologically-based population pharmacokinetic modeling. Case example: Naproxen
Loisios-Konstantinidis, I.; Cristofoletti, R.; Fotaki, N.; Turner, D.B.; Dressman, J.
Zeitschriftenaufsatz
2020Evaluation of potential environmental toxicity of polymeric nanomaterials and surfactants
Hering, Indra; Eilebrecht, Elke; Parnham, Michael J.; Günday-Türeli, Nazende; Türeli, Akif Emre; Weiler, Marc; Schäfers, Christoph; Fenske, Martina; Wacker, Matthias G.
Zeitschriftenaufsatz
2020Evidence of SARS-CoV-2 Infection in Returning Travelers from Wuhan, China
Ciesek, Sandra
Zeitschriftenaufsatz
2020Factors determining microbial colonization of liquid nitrogen storage tanks used for archiving biological samples
Bajerski, F.; Bürger, A.; Glasmacher, B.; Keller, E.R.J.; Müller, K.; Mühldorfer, K.; Nagel, M.; Rüdel, H.; Müller, T.; Schenkel, J.; Overmann, J.
Zeitschriftenaufsatz
2020Fate of acrylamide during coffee roasting and in vitro digestion assessed with carbon 14- and carbon 13-labeled materials
Badoud, Flavia; Göckener, Bernd; Severin, Kevin; Ernest, Marion; Romero, Roman; Alzieu, Thibaut; Glabasnia, Arne; Hamel, Jonas; Bücking, Mark; Delatour, Thierry
Zeitschriftenaufsatz
2020Fate of Chlorpropham during High-Temperature Processing of Potatoes
Göckener, Bernd; Kotthoff, Matthias; Kling, Hans-Willi; Bücking, Mark
Zeitschriftenaufsatz
2020A field study in support of the monitoring of priority substances in German freshwater fish: Derivation of fillet-to-whole fish conversion factors
Rüdel, Heinz; Radermacher, Georg; Fliedner, Annette; Lohmann, Nina; Duffek, Anja
Zeitschriftenaufsatz
2020Flow cytometry-based system for screening of lignin peroxidase mutants with higher oxidative stability
Ilić Đurđić, K.; Ece, S.; Ostafe, R.; Vogel, S.; Balaž, A.M.; Schillberg, S.; Fischer, R.; Prodanovic, R.
Zeitschriftenaufsatz
2020Functional Characterization of Knock-In Mice Expressing a 12/15-Lipoxygenating Alox5 Mutant Instead of the 5-Lipoxygenating Wild-Type Enzyme
Marbach-Breitrück, E.; Kutzner, L.; Rothe, M.; Gurke, R.; Schreiber, Y.; Reddanna, P.; Schebb, N.-H.; Stehling, S.; Wieler, L.H.; Heydeck, D.; Kuhn, H.
Zeitschriftenaufsatz
2020The Fundamental Clustering and Projection Suite (FCPS)
Ultsch, A.; Lötsch, J.
Zeitschriftenaufsatz
2020Gene expression variability between randomly and targeted transgene integration events in tobacco suspension cell lines
Kirchhoff, Janina; Schiermeyer, Andreas; Schneider, Katja; Fischer, Rainer; Ainley, W. Michael; Webb, Steven R.; Schinkel, Helga; Schillberg, Stefan
Zeitschriftenaufsatz
2020Glucagon-like peptide 1 levels predict cardiovascular risk in patients with acute myocardial infarction
Kahles, F.; Rückbeil, M.V.; Mertens, R.W.; Foldenauer, A.C.; Arrivas, M.C.; Moellmann, J.; Lebherz, C.; Biener, M.; Giannitsis, E.; Katus, H.A.; Marx, N.; Lehrke, M.
Zeitschriftenaufsatz
2020A head-to-head comparison of the efficacy and safety of ixekizumab and adalimumab in biological-naïve patients with active psoriatic arthritis: 24-week results of a randomised, open-label, blinded-assessor trial
Mease, P.J.; Smolen, J.S.; Behrens, F.; Nash, P.; Liu Leage, S.; Li, L.; Tahir, H.; Gooderham, M.; Krishnan, E.; Liu-Seifert, H.; Emery, P.; Pillai, S.G.; Helliwell, P.S.
Zeitschriftenaufsatz
2020Identification and molecular analysis of interaction sites in the MtSEO-F1 protein involved in forisome assembly
Rose, J.; Visser, F.; Müller, B.; Senft, M.; Groscurth, S.; Sicking, K.F.; Twyman, R.M.; Prüfer, D.; Noll, G.A.
Zeitschriftenaufsatz
2020Identification of a 2,4-diaminopyrimidine scaffold targeting Trypanosoma brucei pteridine reductase 1 from the LIBRA compound library screening campaign
Linciano, P.; Cullia, G.; Borsari, C.; Santucci, M.; Ferrari, S.; Witt, G.; Gul, S.; Kuzikov, M.; Ellinger, B.; Santarem, N.; Cordeiro da Silva, A.; Conti, P.; Bolognesi, M.L.; Roberti, M.; Prati, F.; Bartoccini, F.; Retini, M.; Piersanti, G.; Cavalli, A.; Goldoni, L.; Bertozzi, S.M.; Bertozzi, F.; Brambilla, E.; Rizzo, V.; Piomelli, D.; Pinto, A.; Bandiera, T.; Costi, M.P.
Zeitschriftenaufsatz
2020Impact of wastewater-borne nanoparticles of silver and titanium dioxide on the swimming behaviour and biochemical markers of Daphnia magna: An integrated approach
Galhano, Victor; Hartmann, Sarah; Monteiro, Marta S.; Zeumer, Richard; Mozhayeva, Darya; Steinhoff, Benedikt; Müller, Katharina; Prenzel, Kirsten; Kunze, Jan; Kuhnert, Klaus-Dieter; Schönherr, Holger; Engelhard, Carsten; Schlechtriem, Christian; Loureiro, Susana; Soares, Amadeu M.V.M.; Witte, Klaudia; Lopes, Isabel
Zeitschriftenaufsatz
2020Implementation of lipidomics in clinical routine: Can fluoride/citrate blood sampling tubes improve preanalytical stability?
Hahnefeld, L.; Gurke, R.; Thomas, D.; Schreiber, Y.; Schäfer, S.M.G.; Trautmann, S.; Snodgrass, I.F.; Kratz, D.; Geisslinger, G.; Ferreiros, N.
Zeitschriftenaufsatz
2020Individual therapeutic DAS28-dcrit responses differentiate between effectiveness of rheumatoid arthritis therapies and reflect patient-reported outcomes
Koehm, M.; McIntosh, M.J.; Hofmann, M.W.; Abraham, V.; Gabay, C.; Choy, E.H.; Kavanaugh, A.; Burkhardt, H.; Behrens, F.
Zeitschriftenaufsatz
2020Inhibition of histone acetylation and deacetylation enzymes affects longevity, development, and fecundity in the pea aphid (Acyrthosiphon pisum)
Kirfel, P.; Skaljac, M.; Grotmann, J.; Kessel, T.; Seip, M.; Michaelis, K.; Vilcinskas, A.
Zeitschriftenaufsatz
2020Innovative Optical-Sensing Technology for the Online Fouling Characterization of Silicon Carbide Membranes during the Treatment of Oily Water
Ebrahimi, M.; Schmidt, A.A.; Kaplan, C.; Schmitz, O.; Czermak, P.
Zeitschriftenaufsatz
2020The insect antimicrobial peptide cecropin A disrupts uropathogenic Escherichia coli biofilms
Kalsy, M.; Tonk, M.; Hardt, M.; Dobrindt, U.; Zdybicka-Barabas, A.; Cytrynska, M.; Vilcinskas, A.; Mukherjee, K.
Zeitschriftenaufsatz
2020Insektizide in Böden unterschiedlicher Bewirtschaftung
Leisner, Jörg; Guhl, Barbara; Hindersmann, Benjamin; Göckener, Bernd
Zeitschriftenaufsatz
2020The iron load of lipocalin-2 (LCN-2) defines its pro-tumour function in clear-cell renal cell carcinoma
Rehwald, C.; Schnetz, M.; Urbschat, A.; Mertens, C.; Meier, J.K.; Bauer, R.; Baer, P.; Winslow, S.; Roos, F.C.; Zwicker, K.; Huard, A.; Weigert, A.; Brüne, B.; Jung, M.
Zeitschriftenaufsatz
2020Local fixation of antibiotics with fibrin spray on soft tissues: Experimental study on the relevance of the application techniques
Verboket, R.; Marzi, I.; Fleck, S.C.; Frank, J.; Janko, M.
Zeitschriftenaufsatz
2020Machine-learned identification of psychological subgroups with relation to pain interference in patients after breast cancer treatments
Sipilä, R.; Kalso, E.; Lötsch, J.
Zeitschriftenaufsatz
2020Machine-learning-based knowledge discovery in rheumatoid arthritis-related registry data to identify predictors of persistent pain
Lötsch, J.; Alfredsson, L.; Lampa, J.
Zeitschriftenaufsatz
2020Machine-learning-derived rules set excludes risk of Parkinson’s disease in patients with olfactory or gustatory symptoms with high accuracy
Lötsch, J.; Haehner, A.; Hummel, T.
Zeitschriftenaufsatz
2020The Major Floral Promoter NtFT5 in Tobacco (Nicotiana tabacum) is a Promising Target for Crop Improvement
Schmidt, F.J.; Zimmermann, M.M.; Wiedmann, D.R.; Lichtenauer, S.; Grundmann, L.; Muth, J.; Twyman, R.M.; Prüfer, D.; Noll, G.A.
Zeitschriftenaufsatz
2020Measuring pH and Buffer Capacity in Fluids Aspirated from the Fasted Upper Gastrointestinal Tract of Healthy Adults
Litou, C.; Psachoulias, D.; Vertzoni, M.; Dressman, J.; Reppas, C.
Zeitschriftenaufsatz
2020Membrane-based steric exclusion chromatography for the purification of a recombinant baculovirus and its application for cell therapy
Lothert, K.; Sprick, G.; Beyer, F.; Lauria, G.; Czermak, P.; Wolff, M.W.
Zeitschriftenaufsatz
2020MicroRNAs regulate innate immunity against uropathogenic and commensal-like Escherichia coli infections in the surrogate insect model Galleria mellonella
Mukherjee, K.; Amsel, D.; Kalsy, M.; Billion, A.; Dobrindt, U.; Vilcinskas, A.
Zeitschriftenaufsatz
2020Molecular farming - the slope of enlightenment
Fischer, R.; Buyel, J.F.
Zeitschriftenaufsatz
2020The omega-3 lipid 17,18-EEQ sensitizes TRPV1 and TRPA1 in sensory neurons through the prostacyclin receptor (IP)
Schäfer, S.M.G.; Sendetski, M.; Angioni, C.; Nüsing, R.; Geisslinger, G.; Scholich, K.; Sisignano, M.
Zeitschriftenaufsatz
2020Opportunities to debottleneck the downstream processing of the oncolytic measles virus
Loewe, D.; Dieken, H.; Grein, T.A.; Weidner, T.; Salzig, D.; Czermak, P.
Zeitschriftenaufsatz
2020Optimizing product quality in molecular farming
Schiermeyer, Andreas
Zeitschriftenaufsatz
2020Persistent, mobile and toxic substances in the environment: A spotlight on current research and regulatory activities
Rüdel, Heinz; Körner, Wolfgang; Letzel, Thomas; Neumann, Michael; Nödler, Karsten; Reemtsma, Thorsten
Zeitschriftenaufsatz
2020Predicting human pharmacokinetics of liposomal temoporfin using a hybrid in silico model
Jablonka, L.; Ashtikar, M.; Gao, G.F.; Thurn, M.; Modh, H.; Wang, J.-W.; Preuß, A.; Scheglmann, D.; Albrecht, V.; Röder, B.; Wacker, M.G.
Zeitschriftenaufsatz
2020The production of isoprene from cellulose using recombinant Clostridium cellulolyticum strains expressing isoprene synthase
Janke, C.; Gaida, S.; Jennewein, S.
Zeitschriftenaufsatz
2020Quintaquinone, a Merosesquiterpene from the Yellow Sponge Verongula cf. rigida Esper
Jiso, A.; Kittiwisut, S.; Chantakul, R.; Yuenyongsawad, S.; Putchakarn, S.; Schäberle, T.F.; Temkitthaworn, P.; Ingkaninan, K.; Chaithirayanon, K.; Plubrukarn, A.
Zeitschriftenaufsatz
2020Rare Loss-of-Function Mutation in SERPINA3 in Generalized Pustular Psoriasis
Frey, S.; Sticht, H.; Wilsmann-Theis, D.; Gerschütz, A.; Wolf, K.; Löhr, S.; Haskamp, S.; Frey, B.; Hahn, M.; Ekici, A.B.; Uebe, S.; Thiel, C.; Reis, A.; Burkhardt, H.; Behrens, F.; Köhm, M.; Rech, J.; Schett, G.; Assmann, G.; Kingo, K.; Koks, S.; Mössner, R.; Prinz, J.C.; Oji, V.; Schulz, P.; Muñoz, L.E.; Kremer, A.E.; Wenzel, J.; Hüffmeier, U.
Zeitschriftenaufsatz
2020Retrospective analysis of cyclic volatile methylsiloxanes in archived German fish samples covering a period of two decades
Radermacher, Georg; Rüdel, Heinz; Wesch, Charlotte; Böhnhardt, Anna; Koschorreck, Jan
Zeitschriftenaufsatz
2020S1P d20:1, an endogenous modulator of S1P d18:1/S1P2-dependent signaling
Vutukuri, R.; Koch, A.; Trautmann, S.; Schreiber, Y.; Thomas, D.; Mayser, F.; Meyer zu Heringdorf, D.; Pfeilschifter, J.; Pfeilschifter, W.; Brunkhorst, R.
Zeitschriftenaufsatz
2020S1PR4-dependent CCL2 production promotes macrophage recruitment in a murine psoriasis model
Schuster, C.; Huard, A.; Sirait-Fischer, E.; Dillmann, C.; Brüne, B.; Weigert, A.
Zeitschriftenaufsatz
2020Saturation mutagenesis to improve the degradation of azo dyes by versatile peroxidase and application in form of VP-coated yeast cell walls
Ilić Đurđić, K.; Ostafe, R.; Đurđević Đelmaš, A.; Popović, N.; Schillberg, S.; Fischer, R.; Prodanovic, R.
Zeitschriftenaufsatz
2020Schulung von Medizinischen Fachangestellten bei hausärztlichen Forschungsprojekten. Wissensgewinn und Unterschiede zwischen einer Präsenzschulung und dem Selbststudium eines Schulungshandbuches
Mergenthal, K.; Schulz-Rothe, S.; Siebenhofer, A.; Gerlach, F.M.; Rossmanith, T.; Petersen, J.J.
Zeitschriftenaufsatz
2020Seasonal phenotype-specific expression of microRNAs during metamorphosis in the European map butterfly Araschnia levana
Mukherjee, K.; Baudach, A.; Vogel, H.; Vilcinskas, A.
Zeitschriftenaufsatz
2020Seasonal variability in metal and metalloid burdens of mussels: Using data from the German Environmental Specimen Bank to evaluate implications for long-term mussel monitoring programs
Knopf, Burkhard; Fliedner, Annette; Radermacher, Georg; Rüdel, Heinz; Paulus, Martin; Pirntke, Ulrike; Koschorreck, Jan
Zeitschriftenaufsatz
2020Silencing of the DNA methyltransferase 1 associated protein 1 (DMAP1) gene in the invasive ladybird Harmonia axyridis implies a role of the DNA methyltransferase 1-DMAP1 complex in female fecundity
Gegner, J.; Gegner, T.; Vogel, H.; Vilcinskas, A.
Zeitschriftenaufsatz
2020Testing the bioaccumulation of manufactured nanomaterials in the freshwater bivalve Corbicula fluminea using a new test method
Kühr, Sebastian; Meisterjahn, Boris; Schröder, Nicola; Knopf, Burkhard; Völker, Doris; Schwirn, Kathrin; Schlechtriem, Christian
Zeitschriftenaufsatz
2020Therapie der Psoriasisarthritis
Köhm, M.; Behrens, F.
Zeitschriftenaufsatz
2020A tiered high-throughput screening approach for evaluation of estrogen and androgen receptor modulation by environmentally relevant bisphenol A substitutes
Keminer, Oliver; Teigeler, Matthias; Kohler, Manfred; Wenzel, Andrea; Arning, Jürgen; Kaßner, Franziska; Windshügel, Björn; Eilebrecht, Elke
Zeitschriftenaufsatz
2020Turbidimetry and dielectric spectroscopy as process analytical technologies for mammalian and insect cell cultures
Käßer, L.; Zitzmann, J.; Grein, T.; Weidner, T.; Salzig, D.; Czermak, P.
Konferenzbeitrag
20193D Printed Modular Immunofiltration Columns for Frequency Mixing-Based Multiplex Magnetic Immunodetection
Achtsnicht, S.; Tödter, J.; Niehues, J.; Telöken, M.; Offenhäusser, A.; Krause, H.J.; Schröper, F.
Zeitschriftenaufsatz
20194 Ds in health research - working together toward rapid precision medicine
Niederberger, E.; Parnham, M.J.; Maas, J.; Geisslinger, G.
Zeitschriftenaufsatz
20195-Amino-1-β-D-Ribofuranosyl-Imidazole-4-Carboxamide (AICAR) Reduces Peripheral Inflammation by Macrophage Phenotype Shift
Martin, L.M.; Möller, M.; Weiss, U.; Russe, O.Q.; Scholich, K.; Pierre, S.; Geisslinger, G.; Niederberger, E.
Zeitschriftenaufsatz
2019α-Amino Diphenyl Phosphonates as Novel Inhibitors of Escherichia coli ClpP Protease
Moreno-Cinos, C.; Sassetti, E.; Salado, I.G.; Witt, G.; Benramdane, S.; Reinhardt, L.; Cruz, C.D.; Joossens, J.; Veken, P. Van der; Brötz-Oesterhe, H.; Tammela, P.; Winterhalter, M.; Gribbon, P.; Windshügel, B.; Augustyns, K.
Zeitschriftenaufsatz
2019Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform
Moraes, C.B.; Witt, G.; Kuzikov, M.; Ellinper, B.; Calogeropoulou, T.; Prousis, K.C.; Mangani, S.; Pisa, F. di; Landi, G.; Dello Lacono, L.; Pozzi, C.; Freitas, L.H.; Pascoalino, B.D.; Bertolacini, C.P.; Behrens, B.; Keminer, O.; Leu, J.; Wolf, M.; Reinshagen, J.; Cordeiro-da-Silva, A.; Santarem, N.; Venturelli, A.; Wrigley, S.; Karunakaran, D.; Kebede, B.; Pohner, I.; Muller, W.; Panecka-Hofman, J.; Wade, R.C.; Fenske, M.; Clos, J.; Alunda, J.M.; Corral, M.J.; Uliassi, E.; Bolognesi, M.L.; Linciano, P.; Quotadamo, A.; Ferrari, S.; Santucci, M.; Borsari, C.; Costi, M.P.; Gul, S.
Zeitschriftenaufsatz
2019Achievement Of CDAPSA Low Disease Activity Or Remission Is Associated With Control Of Articular And Extra-Articular Manifestations Of Active Psoriatic Arthritis In Subjects Treated With Apremilast
Coates, L.C.; Mease, P.J.; Behrens, F.; Orbai, A.M.; Ogdie, A.; Brunori, M.; Teng, L.; Guerette, B.; Smolen, J.S.
Abstract
2019Activated Cross-linked Agarose for the Rapid Development of Affinity Chromatography Resins - Antibody Capture as a Case Study
Knödler, M.; Rühl, C.; Opdensteinen, P.; Buyel, J.F.
Zeitschriftenaufsatz
2019Activation of Caspase-6 Is Promoted by a Mutant Huntingtin Fragment and Blocked by an Allosteric Inhibitor Compound
Ehrnhoefer, D.E.; Skotte, N.H.; Reinshagen, J.; Qiu, X.; Windshügel, B.; Jaishankar, P.; Ladha, S.; Petina, O.; Khankischpur, M.; Nguyen, Y.T.N.; Caron, N.S.; Razeto, A.; Meyer zu Rheda, M.; Deng, Y.; Huynh, K.T.; Wittig, I.; Gribbon, P.; Renslo, A.R.; Geffken, D.; Gul, S.; Hayden, M.R.
Zeitschriftenaufsatz
2019ADAM15 in Apoptosis Resistance of Synovial Fibroblasts
Janczi, T.; Böhm, B.B.; Fehrl, Y.; DeGiacomo, P.; Kinne, R.W.; Burkhardt, H.
Zeitschriftenaufsatz
2019Addition or removal of concomitant methotrexate alters adalimumab effectiveness in rheumatoid arthritis but not psoriatic arthritis
Behrens, F.; Koehm, M.; Schwaneck, E.C.; Schmalzing, M.; Wittig, B.M.; Gnann, H.; Greger, G.; Tony, H.P.; Burkhardt, H.
Zeitschriftenaufsatz
2019Advanced in silico modeling explains pharmacokinetics and biodistribution of temoporfin nanocrystals in humans
Jablonka, L.; Ashtikar, M.; Gao, G.; Jung, F.; Thurn, M.; Preuß, A.; Scheglmann, D.; Albrecht, V.; Röder, B.; Wacker, M.G.
Zeitschriftenaufsatz
2019Aeration and Shear Stress Are Critical Process Parameters for the Production of Oncolytic Measles Virus
Grein, T.A.; Loewe, D.; Dieken, H.; Weidner, T.; Salzig, D.; Czermak, P.
Zeitschriftenaufsatz
2019Aktuelle Therapie der Psoriasisarthritis
Köhm, M.; Behrens, F.
Zeitschriftenaufsatz
2019Alternativen zum Wachstum
Schäfers, Christoph; Bette, Kristina; Herrmann, Florian; Nawroth, Georg
Aufsatz in Buch
2019Analyses of association of psoriatic arthritis and psoriasis vulgaris with functional NCF1 variants
Löhr, S.; Ekici, A.B.; Uebe, S.; Büttner, C.; Köhm, M.; Behrens, F.; Böhm, B.; Sticherling, M.; Schett, G.; Simon, D.; Mössner, R.; Nimeh, A.; Oji, V.; Assmann, G.; Rech, J.; Holmdahl, R.; Burkhardt, H.; Reis, A.; Hüffmeier, U.
Zeitschriftenaufsatz
2019Antibacterial and antifungal activity of defensins from the Australian paralysis tick, Ixodes holocyclus
Cabezas-Cruz, A.; Tonk, M.; Bleackley, M.R.; Valdes, J.J.; Barrero, R.A.; Hernández-Jarguín, A.; Moutailler, S.; Vilcinskas, A.; Richard-Forget, F.; Anderson, M.A.; Rodriguez-Valle, M.
Zeitschriftenaufsatz
2019Antibiotic-producing beneficial bacteria in the gut of the burying beetle nicrophorus vespilloides
Heise, P.; Liu, Y.; Degenkolb, T.; Vogel, H.; Schäberle, T.F.; Vilcinskas, A.
Zeitschriftenaufsatz
2019The Antisteatotic and Hypolipidemic Effect of Insect Meal in Obese Zucker Rats is Accompanied by Profound Changes in Hepatic Phospholipid and 1-Carbon Metabolism
Meyer, S.; Gessner, D.K.; Wen, G.; Most, E.; Liebisch, G.; Zorn, H.; Ringseis, R.; Eder, K.
Zeitschriftenaufsatz
2019Application of a Refined Developability Classification System
Rosenberger, J.; Butler, J.; Muenster, U.; Dressman, J.
Zeitschriftenaufsatz
2019Application of adverse outcome pathways and quantitative in vitro-in vivo extrapolation (QIVIVE) modelling for risk assessment based on in vitro data
Mally, A.; Birk, B.; Fiore, S. di; Ellinger, B.; Jarzina, S.; Reiser, P.; Taverne, F.; Kramer, N.
Abstract
2019Application of the relationship between pharmacokinetics and pharmacodynamics in drug development and therapeutic equivalence: a PEARRL review
Loisios‐Konstantinidis, I.; Paraiso, R.L.M.; Fotaki, N.; McAllister, M.; Cristofoletti, R.; Dressman, J.
Zeitschriftenaufsatz
2019Association analyses of functional NCF1 variants in psoriatic arthritis and psoriasis vulgaris
Hüffmeier, U.D.; Löhr, S.; Ekici, A.B.; Uebe, S.; Köhm, M.; Behrens, F.; Böhm, B.; Sticherling, M.; Schett, G.; Mössner, R.; Nimeh, A.; Assmann, G.; Rech, J.; Oji, V.; Holmdahl, R.; Burkhardt, H.; Reis, A.
Abstract
2019Bewertung des endokrinen Potenzials von Bisphenol Alternativstoffen in umweltrelevanten Verwendungen. Abschlussbericht
Eilebrecht, Elke; Wenzel, Andrea; Teigeler, Matthias; Windshügel, Björn; Keminer, Oliver; Chachulski, Laura; Kohler, Manfred
Bericht
2019Beyond leukotriene formation
Häfner, A.-K.; Kahnt, A.S.; Steinhilber, D.
Zeitschriftenaufsatz
2019Biglycan evokes autophagy in macrophages via a novel CD44/Toll-like receptor 4 signaling axis in ischemia/reperfusion injury
Poluzzi, C.; Nastase, M.-V.; Zeng-Brouwers, J.; Roedig, H.; Tzung-Harn Hsieh, L.; Michaelis, J.B.; Buhl, E.M.; Rezende, F.; Manavski, Y.; Bleich, A.; Boor, P.; Brandes, R.P.; Pfeilschifter, J.; Stelzer, E.H.K.; Münch, C.; Dikic, I.; Brandts, C.; Iozzo, R.V.; Wygrecka, M.; Schäfer, L.
Zeitschriftenaufsatz
2019Bioconcentration studies with the freshwater amphipod Hyalella azteca: Are the results predictive of bioconcentration in fish?
Schlechtriem, Christian; Kampe, Sebastian; Bruckert, Hans-Jörg; Bischof, Ina; Ebersbach, Ina; Kosfeld, Verena; Kotthoff, Matthias; Schäfers, Christoph; L’Haridon, Jacques
Zeitschriftenaufsatz
2019Biodegradation of Volatile Chemicals in Soil: Separating Volatilization and Degradation in an Improved Test Setup (OECD 307)
Shrestha, Prasit; Meisterjahn, Boris; Klein, Michael; Mayer, Philipp; Birch, Heidi; Hughes, Christopher B.; Hennecke, Dieter
Zeitschriftenaufsatz
2019Biodegradation testing of hydrophobic and volatile organic chemicals
Shrestha, Prasit
: Hennecke, Dieter; Mayer, Philipp
Dissertation
2019Biorelevant dissolution testing of a weak base: Interlaboratory reproducibility and investigation of parameters controlling in vitro precipitation
Berben, P.; Ashworth, L.; Beato, S.; Bevernage, J.; Bruel, J.-L.; Butler, J.; Dressman, J.; Schäfer, K.; Hutchins, P.; Klumpp, L.; Mann, J.; Nicolai, J.; Ojala, K.; Patel, S.; Powell, S.; Rosenblatt, K.; Tomaszewska, I.; Williams, J.; Augustijns, P.
Zeitschriftenaufsatz
2019Biosynthesis of Stereoisomers of Dill Ether and Wine Lactone by Pleurotus sapidus
Trapp, T.; Kirchner, T.; Birk, F.; Fraatz, M.A.; Zorn, H.
Zeitschriftenaufsatz
2019Biosynthetic Basis for Structural Diversity of Aminophenylpyrrole-Derived Alkaloids
Linares-Otoya, L.; Liu, Y.; Linares-Otoya, V.; Armas-Mantilla, L.; Crüsemann, M.; Ganoza-Yupanqui, M.L.; Campos-Florian, J.; König, G.M.; Schäberle, T.F.
Zeitschriftenaufsatz
2019Calculation of drug-polymer mixing enthalpy as a new screening method of precipitation inhibitors for supersaturating pharmaceutical formulations
Price, D.J.; Nair, A.; Kuentz, M.; Dressman, J.; Saal, C.
Zeitschriftenaufsatz
2019Canakinumab For The Treatment Of Adult Onset Still's Disease To Achieve Reduction Of Arthritic Manifestation At Week 12: An Investigator-Initiated Multi-Centre, Placebo-Controlled Study (Consider)
Kedor, C.; Listing, J.; Zernicke, J.; Weiss, A.; Behrens, F.; Blank, N.; Henes, J.; Kekow, J.; Rubbert-Roth, A.; Schulze-Koops, H.; Seipelt, E.; Specker, C.; Feist, E.
Abstract
2019Cancer-induced inflammation and inflammation-induced cancer in colon: A role for S1P lyase
Schwiebs, A.; Herrero San Juan, M.; Schmidt, K.G.; Wiercinska, E.; Anlauf, M.; Ottenlinger, F.; Thomas, D.; Elwakeel, E.; Weigert, A.; Farin, H.F.; Bonig, H.; Scholich, K.; Geisslinger, G.; Pfeilschifter, J.M.; Radeke, H.H.
Zeitschriftenaufsatz
2019Capillary electrophoresis‐based enzyme assays for β‐lactamase enzymes
Chen, C.; Kramer, J.S.; Brunst, S.; Proschak, E.; Scriba, G.K.E.
Zeitschriftenaufsatz
2019Carboxylic acid consumption and production by Corynebacterium glutamicum
Conrady, M.; Lemoine, A.; Limberg, M.H.; Oldiges, M.; Neubauer, P.; Junne, S.
Zeitschriftenaufsatz
2019Ceramides as Novel Disease Biomarkers
Kurz, J.; Parnham, M.J.; Geisslinger, G.; Schiffmann, S.
Zeitschriftenaufsatz
2019Certainties and uncertainties in accessing toxicity of non‑extractable residues (NER) in soil
Harmsen, Joop; Hennecke, Dieter; Hund-Rinke, Kerstin; Lahr, Joost; Deneer, John
Zeitschriftenaufsatz
2019Characterization Of Patients With Inflammatory Bowel Disease In The Ankylosing Spondylitis Cohort Prior And During Adalimumab Treatment: Data From A Large German Non-Interventional Study
Köhm, M.; Schmalzing, M.; Schwaneck, E.C.; Gnann, H.; Tony, H.P.; Greger, G.; Boas, A.; Burkhardt, H.; Behrens, F.
Abstract
2019Chronic Hypoxia Enhances β-Oxidation-Dependent Electron Transport via Electron Transferring Flavoproteins
Fuhrmann, D.C.; Olesch, C.; Kurrle, N.; Schnütgen, F.; Zukunft, S.; Fleming, I.; Brüne, B.
Zeitschriftenaufsatz
2019Circular synthesized CRISPR/Cas gRNAs for functional interrogations in the coding and noncoding genome
Wegner, M.; Diehl, V.; Bittl, V.; Bruyn, R. de; Wiechmann, S.; Matthess, Y.; Heber, M.; Hayes, M.G.B.; Schaubeck, S.; Benner, C.; Heinz, S.; Bremm, A.; Dikic, I.; Ernst, A.; Kaulich, M.
Zeitschriftenaufsatz
2019Clinical Usefulness of Self-Rated Olfactory Performance - A Data Science-Based Assessment of 6000 Patients
Lötsch, J.; Hummel, T.
Zeitschriftenaufsatz
2019Closing gaps for environmental risk screening of engineered nanomaterials
Kühnel, D.; Nickel, C.; Hellack, B.; Zalm, E. van der; Kussatz, C.; Herrchen, M.; Meisterjahn, B.; Hund-Rinke, K.
Zeitschriftenaufsatz
2019Clot derived contaminants in transplanted cells enhance inflammation at peri-stroke area after bone marrow mononuclear cell transplantation in murine stroke model
Taura, A.; Ogawa, Y.; Okinaka, Y.; Takeuchi, Y.; Boltze, J.; Gul, S.; Claussen, C.; Taguchi, A.
Abstract
2019Clot-Derived Contaminants in Transplanted Bone Marrow Mononuclear Cells Impair the Therapeutic Effect in Stroke
Okinaka, Y.; Kikuchi-Taura, A.; Takeuchi, Y.; Ogawa, Y.; Boltze, J.; Gul, S.; Claussen, C.; Taguchi, A.
Zeitschriftenaufsatz
2019Co-cultivation: A powerful tool for insulin-producing beta cell manufacturing
Petry, F.; Czermak, P.; Salzig, D.
Abstract
2019Combination of membrane-based and chromatographic methods to achieve pure and concentrated oncolytic measles viruses
Loewe, D.; Dieken, H.; Grein, T.; Salzig, D.; Czermak, P.
Abstract
2019A combined FSTRA-shotgun proteomics approach to identify molecular changes in zebrafish upon chemical exposure
Ayobahan, S.U.; Eilebrecht, E.; Kotthoff, M.; Baumann, L.; Eilebrecht, S.; Teigeler, M.; Hollert, H.; Kalkhof, S.; Schäfers, C.
Zeitschriftenaufsatz
2019A Combined Ultrafiltration/Diafiltration Step Facilitates the Purification of Cyanovirin-N From Transgenic Tobacco Extracts
Opdensteinen, P.; Clodt, J.I.; Müschen, C.R.; Filiz, V.; Buyel, J.F.
Zeitschriftenaufsatz
2019Combining biorelevant in vitro and in silico tools to simulate and better understand the in vivo performance of a nano-sized formulation of aprepitant in the fasted and fed states
Litou, C.; Patel, N.; Turner, D.B.; Kostewicz, E.; Kuentz, M.; Box, K.J.; Dressman, J.
Zeitschriftenaufsatz
2019Comparative estrogenicity of endogenous, environmental and dietary estrogens in pregnant women II
Pande, P.; Fleck, S.C.; Twaddle, N.C.; Churchwell, M.I.; Doerge, D.R.; Teeguarden, J.G.
Zeitschriftenaufsatz
2019Comparative multi-generation study on long-term effects of pristine and wastewater-borne silver and titanium dioxide nanoparticles on key lifecycle parameters in Daphnia magna
Hartmann, S.; Louch, R.; Zeumer, R.; Steinhoff, B.; Mozhayeva, D.; Engelhard, C.; Schönherr, H.; Schlechtriem, C.; Witte, K.
Zeitschriftenaufsatz
2019Comparison of different methodologies for selecting PELMO input parameters for groundwater modelling of plant protection products including current EU guidance (SANC0/12117/2014 - final, 2014)
Klein, Michael
Bericht
2019A comparison of log Kow (n‑octanol-water partition coefficient) values for non‑ionic, anionic, cationic and amphoteric surfactants determined using predictions and experimental methods
Hodges, Geoff; Eadsforth, Charles; Bossuyt, Bart; Bouvy, Alain; Enrici, Marie‑Helene; Geurts, Marc; Kotthoff, Matthias; Michie, Eleanor; Miller, Dennis; Müller, Josef; Oetter, Gunter; Roberts, Jayne; Schowanek, Diederik; Sun, Ping; Venzmer, Joachim
Zeitschriftenaufsatz
2019Comparison of microbial and transient expression (tobacco plants and plant-cell packs) for the production and purification of the anticancer mistletoe lectin viscumin
Gengenbach, B.B.; Keil, L.L.; Opdensteinen, P.; Müschen, C.R.; Melmer, G.; Lentzen, H.; Bührmann, J.; Buyel, J.F.
Zeitschriftenaufsatz
2019Comparison of the environmental properties of parasiticides and harmonisation of the basis for environmental assessment at the EU level
Römbke, Jörg; Duis, Karen; Egeler, Philipp; Gilberg, Daniel; Schuh, Christine; Herrchen, Monika; Hennecke, Dieter; Hölzle, Ludwig E.; Heilmann-Thudium, Brigitte; Wohde, Manuel; Wagner, Julia; Düring, Rolf-Alexander
Bericht
2019Complete genome sequence of the corallopyronin a-producing myxobacterium corallococcus coralloides B035
Bouhired, S.; Rupp, O.; Blom, J.; Schäberle, T.F.; Schiefer, A.; Kehraus, S.; Pfarr, K.; Goesmann, A.; Hoerauf, A.; König, G.
Zeitschriftenaufsatz
2019The complete mitochondrial genome of the hymenopteran hunting robber fly Dasypogon diadema
Drukewitz, S.H.; Jauss, R.-T.; Bokelmann, L.; Reumont, B.M. von
Zeitschriftenaufsatz
2019Computational functional genomics-based reduction of disease-related gene sets to their key components
Lippmann, C.; Ultsch, A.; Lötsch, J.
Zeitschriftenaufsatz
2019Computer-Aided Selective Optimization of Side Activities of Talinolol
Hiesinger, K.; Kramer, J.S.; Achenbach, J.; Moser, D.; Weber, J.; Wittmann, S.K.; Morisseau, C.; Angioni, C.; Geisslinger, G.; Kahnt, A.S.; Kaiser, A.; Proschak, A.; Steinhilber, D.; Pogoryelov, D.; Wagner, K.; Hammock, B.D.; Proschak, E.
Zeitschriftenaufsatz
2019Computer-Assisted Discovery and Structural Optimization of a Novel Retinoid X Receptor Agonist Chemotype
Heitel, P.; Gellrich, L.; Kalinowsky, L.; Heering, J.; Kaiser, A.; Ohrndorf, J.; Proschak, E.; Merk, D.
Zeitschriftenaufsatz
2019The conspicuous postmetamorphic coloration of fire salamanders, but not their toxicity, is affected by larval background albedo
Sanchez, E.; Pröhl, H.; Lüddecke, T.; Schulz, S.; Steinfartz, S.; Vences, M.
Zeitschriftenaufsatz
2019Conversion of chitin to defined chitosan oligomers: Current status and future prospects
Schmitz, C.; Auza, L.G.; Koberidze, D.; Rasche, S.; Fischer, R.; Bortesi, L.
Zeitschriftenaufsatz
2019Correction to: Progress on bringing together raptor collections in Europe for contaminant research and monitoring in relation to chemicals regulation (Environmental Science and Pollution Research, (2019), 26, 20, (20132-20136), 10.1007/s11356-019-05340-6)
Movalli, P.; Duke, G.; Ramello, G.; Dekker, R.; Vrezec, A.; Shore, R.F.; García-Fernández, A.; Wernham, C.; Krone, O.; Alygizakis, N.; Badry, A.; Barbagli, F.; Biesmeijer, K.; Boano, G.; Bond, A.L.; Choresh, Y.; Christensen, J.B.; Cincinelli, A.; Danielsson, S.; Dias, A.; Dietz, R.; Eens, M.; Espín, S.; Eulaers, I.; Frahnert, S.; Fuiz, T.I.; Gkotsis, G.; Glowacka, N.; Gómez-Ramírez, P.; Grotti, M.; Guiraud, M.; Hosner, P.; Johansson, U.; Jaspers, V.L.B.; Kamminga, P.; Koschorreck, J.; Knopf, B.; Kubin, E.; Brutto, S.L.; Lourenco, R.; Martellini, T.; Martínez-López, E.; Mateo, R.; Nika, M.-C.; Nikolopoulou, V.; Osborn, D.; Pauwels, O.; Pavia, M.; Pereira, M.G.; Rüdel, H.; Sanchez-Virosta, P.; Slobodnik, J.; Sonne, C.; Thomaidis, N.; Töpfer, T.; Treu, G.; Väinölä, R.; Valkama, J.; Mije, S. van der; Vangeluwe, D.; Warren, B.H.; Woog, F.
Zeitschriftenaufsatz
2019The Correlation Between DsRed mRNA Levels and Transient DsRed Protein Expression in Plants Depends on Leaf Age and the 5′ Untranslated Region
Jansing, J.; Buyel, J.F.
Zeitschriftenaufsatz
2019Critical analysis of the commercial potential of plants for the production of recombinant proteins
Schillberg, S.; Raven, N.; Spiegel, H.; Rasche, S.; Buntru, M.
Zeitschriftenaufsatz
2019Curvature induction and membrane remodeling by FAM134B reticulon homology domain assist selective ER-phagy
Bhaskara, R.M.; Grumati, P.; Garcia-Pardo, J.; Kalayil, S.; Covarrubias-Pinto, A.; Chen, W.; Kudryashev, M.; Dikic, I.; Hummer, G.
Zeitschriftenaufsatz
2019CXCL16/CXCR6-mediated adhesion of human peripheral blood mononuclear cells to inflamed endothelium
Linke, B.; Meyer Dos Santos, S.; Picard-Willems, B.; Keese, M.; Harder, S.; Geisslinger, G.; Scholich, K.
Zeitschriftenaufsatz
2019CYRI/FAM49B negatively regulates RAC1-driven cytoskeletal remodelling and protects against bacterial infection
Yuki, K.E.; Marei, H.; Fiskin, E.; Eva, M.M.; Gopal, A.A.; Schwartzentruber, J.A.; Majewski, J.; Cellier, M.; Mandl, J.N.; Vidal, S.M.; Malo, D.; Dikic, I.
Zeitschriftenaufsatz
2019Cytokine-induced endogenous production of prostaglandin D2 is essential for human group 2 innate lymphoid cell activation
Maric, J.; Ravindran, A.; Mazzurana, L.; Acker, A. van; Rao, A.; Kokkinou, E.; Ekoff, M.; Thomas, D.; Fauland, A.; Nilsson, G.; Wheelock, C.E.; Dahlen, S.-E.; Ferreiros, N.; Geisslinger, G.; Friberg, D.; Heinemann, A.; Konya, V.; Mjösberg, J.
Zeitschriftenaufsatz
2019A Data Science-Based Analysis Points at Distinct Patterns of Lipid Mediator Plasma Concentrations in Patients with Dementia
Gurke, R.; Etyemez, S.; Prvulovic, D.; Thomas, D.; Fleck, S.C.; Reif, A.; Geisslinger, G.; Lötsch, J.
Zeitschriftenaufsatz
2019Degradation and transformation of fluoroquinolones by microorganisms with special emphasis on ciprofloxacin
Rusch, M.; Spielmeyer, A.; Zorn, H.; Hamscher, G.
Zeitschriftenaufsatz
2019Description of a new Moridilla species from North Sulawesi, Indonesia (Mollusca: Nudibranchia: Aeolidioidea) - based on MicroCT, histological and molecular analyses
Schillo, D.; Wipfler, B.; Undap, N.; Papu, A.; Böhringer, N.; Eisenbarth, J.-H.; Kaligis, F.; Bara, R.; Schäberle, T.F.; König, G.M.; Wägele, H.
Zeitschriftenaufsatz
2019Description of defensive postures of the natterjack toad epidalea calamita (Laurenti 1768) and notes on the release of toxic secretions
Stawikowski, R.; Lüddecke, T.
Zeitschriftenaufsatz
2019Determination of endocannabinoids and endocannabinoid-like substances in human K3EDTA plasma - LC-MS/MS method validation and pre-analytical characteristics
Gurke, R.; Thomas, D.; Schreiber, Y.; Schäfer, S.M.G.; Fleck, S.C.; Geisslinger, G.; Ferreiros, N.
Zeitschriftenaufsatz
2019Deubiquitinase USP10 regulates Notch signaling in the endothelium
Lim, R.; Sugino, T.; Nolte, H.; Andrade, J.; Zimmermann, B.; Shi, C.; Doddaballapur, A.; Ong, Y.T.; Wilhelm, K.; Fasse, J.W.D.; Ernst, A.; Kaulich, M.; Husnjak, K.; Boettger, T.; Guenther, S.; Braun, T.; Krüger, M.; Benedito, R.; Dikic, I.; Potente, M.
Zeitschriftenaufsatz
2019Development of a metabolic pathway transfer and genomic integration system for the syngas-fermenting bacterium Clostridium ljungdahlii
Philipps, G.; Vries, S. de; Jennewein, S.
Zeitschriftenaufsatz
2019Development of multitarget agents possessing soluble epoxide hydrolase inhibitory activity
Hiesinger, K.; Wagner, K.M.; Hammock, B.D.; Proschak, E.; Hwang, S.H.
Zeitschriftenaufsatz
2019Development study of pectin/Surelease® solid microparticles for the delivery of L-alanyl-L-glutamine dipeptide
Nova, M.V.; Nothnagel, L.; Thurn, M.; Travassos, P.B.; Herculano, L.S.; Bittencourt, P.R.S.; Novello, C.R.; Bazotte, R.B.; Wacker, M.G.; Bruschi, M.L.
Zeitschriftenaufsatz
2019A dialysis-based in vitro drug release assay to study dynamics of the drug-protein transfer of temoporfin liposomes
Wallenwein, C.M.; Villa Nova, M.; Janas, C.; Jablonka, L.; Gao, G.F.; Thurn, M.; Albrecht, V.; Wiehe, A.; Wacker, M.G.
Zeitschriftenaufsatz
2019Discovery of a benzothiophene-flavonol halting miltefosine and antimonial drug resistance in Leishmania parasites through the application of medicinal chemistry, screening and genomics
Borsari, C.; Jiménez-Antón, M.D.; Eick, J.; Bifeld, E.; Torrado, J.J.; Olías-Molero, A.I.; Corral, M.J.; Santarem, N.; Baptista, C.; Severi, L.; Gul, S.; Wolf, M.; Kuzikov, M.; Ellinger, B.; Reinshagen, J.; Witt, G.; Linciano, P.; Tait, A.; Costantino, L.; Luciani, R.; Tejera Nevado, P.; Zander-Dinse, D.; Franco, C.H.; Ferrari, S.; Moraes, C.B.; Cordeiro-da-Silva, A.; Ponterini, G.; Clos, J.; Alunda, J.M.; Costi, M.P.
Zeitschriftenaufsatz
2019Discovery of the First in Vivo Active Inhibitors of the Soluble Epoxide Hydrolase Phosphatase Domain
Kramer, JS.; Woltersdorf, S.; Duflot, T.; Hiesinger, K.; Lillich, FF.; Knoll, F.; Wittmann, SK.; Klingler, FM.; Brunst, S.; Chaikuad, A.; Morisseau, C.; Hammock, BD.; Buccellati, C.; Sala, A.; Rovati, GE.; Leuillier, M.; Fraineau, S.; Rondeaux, J.; Hernandez-Olmos, V.; Heering, J.; Merk, D.; Pogoryelov, D.; Steinhilber, D.; Knapp, S.; Bellien, J.; Proschak, E.
Zeitschriftenaufsatz
2019Discovery pipelines for marine resources: An ocean of opportunity for biotechnology?
Smith, D.; Buddie, A.G.; Goss, R.J.M.; Overmann, J.; Lepleux, C.; Brönstrup, M.; Kloareg, B.; Meiners, T.; Brennecke, P.; Ianora, A.; Bouget, F.-Y.; Gribbon, P.; Pina, M.
Zeitschriftenaufsatz
2019Distal infraorbital nerve injury
Hardt, S.; Fischer, C; Vogel, A.; Wilken-Schmitz, A.; Tegeder, I.
Zeitschriftenaufsatz
2019Downstream processing of Cry4AaCter-induced inclusion bodies containing insect-derived antimicrobial peptides produced in Escherichia coli
Hoffmann, D.; Eckhardt, D.; Gerlach, D.; Vilcinskas, A.; Czermak, P.
Zeitschriftenaufsatz
2019Driving next-generation autophagy researchers towards translation (DRIVE), an international PhD training program on autophagy
Kraft, C.; Boya, P.; Codogno, P.; Elazar, Z.; Eskelinen, E.-L.; Farres, J.; Kirkin, V.; Jungbluth, H.; Martinez, A.; Pless, O.; Primard, C.; Proikas-Cezanne, T.; Simonsen, A.; Reggiori, F.
Zeitschriftenaufsatz
2019The Drosophila melanogaster antimicrobial peptides Mtk-1 and Mtk-2 are active against the malarial parasite Plasmodium falciparum
Tonk, M.; Pierrot, C.; Cabezas-Cruz, A.; Rahnamaeian, M.; Khalife, J.; Vilcinskas, A.
Zeitschriftenaufsatz
2019Effects of continuous theta-burst stimulation of the primary motor and secondary somatosensory areas on the central processing and the perception of trigeminal nociceptive input in healthy volunteers
Annak, O.; Heidegger, T.; Walter, C.; Deichmann, R.; Nöth, U.; Hansen-Goos, O.; Ziemann, U.; Lötsch, J.
Zeitschriftenaufsatz
2019The effects of gibberellic acid on allium cepa root tip meristematic cells
Tütünoğlu, B.; Aksoy, Ö.; Özbek, R.; Uçkan, F.
Zeitschriftenaufsatz
2019Efficacy Of Etanercept Over A Period Of 12 Months In The Routine Treatment Of Patients With RA, AxSpA, PsA Or Pso: Final Results Of A German Non-Interventional, Prospective, Multi-Center Study (Adequate)
Feist, E.; Baraliakos, X.; Behrens, F.; Thaci, D.; Klopsch, T.; Plenske, A.; Blindzellner, L.K.; Meng, T.; Löschmann, P.A.
Abstract
2019Elimination of HER3-expressing breast cancer cells using aptamer-siRNA chimeras
Nachreiner, I.; Hussain, A.F.; Wullner, U.; Machuy, N.; Meyer, T.F.; Fischer, R.; Gattenlöhner, S.; Meinhold-Heerlein, I.; Barth, S.; Tur, M.K.
Zeitschriftenaufsatz
2019Elucidation of chemical modifier reactivity towards peptides and proteins and the analysis of specific fragmentation by matrix‐assisted laser desorption/ionization collision‐induced dissociation tandem mass spectrometry
Rühl, M.; Kühn, B.; Roos, J.; Maier, T.J.; Steinhilber, D.; Karas, M.
Zeitschriftenaufsatz, Konferenzbeitrag
2019Endokrin wirksame Umweltchemikalien in Lebensmitteln
Schäfers, C.; Licht, O.; Bitsch, A.
Zeitschriftenaufsatz
2019Enhancement of Benzothiazoles as Pteridine Reductase-1 Inhibitors for the Treatment of Trypanosomatidic Infections
Linciano, P.; Pozzi, C.; Iacono, L. dello; Pisa, F. di; Landi, G.; Bonucci, A.; Gul, S.; Kuzikov, M.; Ellinger, B.; Witt, G.; Santarem, N.; Baptista, C.; Franco, C.; Moraes, C.B.; Müller, W.; Wittig, U.; Luciani, R.; Sesenna, A.; Quotadamo, A.; Ferrari, S.; Pöhner, I.; Cordeiro-da-Silva, A.; Mangani, S.; Costantino, L.; Costi, M.P.
Zeitschriftenaufsatz
2019Environmental contamination with persistent cyclic mustard gas impurities and transformation products
Chmielińska, Katarzyna; Hubé, Daniel; Bausinger, Tobias; Simon, Markus; Rivière, Gilles; Fauser, Patrik; Sanderson, Hans
Zeitschriftenaufsatz
2019The enzymes OSC1 and CYP716A263 produce a high variety of triterpenoids in the latex of Taraxacum koksaghyz
Pütter, K.M.; Deenen, N. van; Müller, B.; Fuchs, L.; Vorwerk, K.; Unland, K.; Bröker, J.N.; Scherer, E.; Huber, C.; Eisenreich, W.; Prüfer, D.; Schulze Gronover, C.
Zeitschriftenaufsatz
2019Epigenetic Mechanisms Are Involved in Sex-Specific Trans-Generational Immune Priming in the Lepidopteran Model Host Manduca sexta
Gegner, J.; Baudach, A.; Mukherjee, K.; Halitschke, R.; Vogel, H.; Vilcinska, A.
Zeitschriftenaufsatz
2019Epigenetic mechanisms mediate the experimental evolution of resistance against parasitic fungi in the greater wax moth Galleria mellonella
Mukherjee, K.; Dubovskiy, I.; Grizanova, E.; Lehmann, R.; Vilcinskas, A.
Zeitschriftenaufsatz
2019ER-Mitochondria Communication in Cells of the Innate Immune System
Namgaladze, D.; Khodzhaeva, V.; Brüne, B.
Zeitschriftenaufsatz
2019EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology
Brennecke, P.; Rasina, D.; Aubi, O.; Herzog, K.; Landskron, J.; Cautain, B.; Vicente, F.; Quintana, J.; Mestres, J.; Stechmann, B.; Ellinger, B.; Brea, J.; Kolanowski, J.L.; Pilarski, R.; Orzaez, M.; Pineda-Lucena, A.; Laraia, L.; Nami, F.; Zielenkiewicz, P.; Paruch, K.; Hansen, E.; Kries, J.P. von; Neuenschwander, M.; Specker, E.; Bartunek, P.; Simova, S.; Lesnikowski, Z.; Krauss, S.; Lehtio, L.; Bilitewski, U.; Bronstrup, M.; Tasken, K.; Jirgensons, A.; Lickert, H.; Clausen, M.H.; Andersen, J.H.; Vicent, M.J.; Genilloud, O.; Martinez, A.; Nazare, M.; Fecke, W.; Gribbon, P.
Zeitschriftenaufsatz
2019Evaluation of microbial shifts caused by a silver nanomaterial: Comparison of four test systems
Hund-Rinke, Kerstin; Hümmler, Anna; Schlinkert, Ruben; Wege, Franziska; Broll, Gabriele
Zeitschriftenaufsatz
2019Evolutionary ecology of parasitic fungi and their host insects
Vilcinskas, A.
Zeitschriftenaufsatz
2019Fast Multiplex real time PCR method for sex-identification of medaka (Oryzias latipes) by non-invasive sampling
Diaz, C.; Böhle, G.; Wege, F.; Teigeler, M.; Eilebrecht, E.
Zeitschriftenaufsatz
2019Fate of a perfluoroalkyl acid mixture in an agricultural soil studied in lysimeters
McLachlan, M.S.; Felizeter, S.; Klein, M.; Kotthoff, M.; Voogt, P. de
Zeitschriftenaufsatz
2019First evidence of anticoagulant rodenticides in fish and suspended particulate matter: Spatial and temporal distribution in German freshwater aquatic systems
Kotthoff, Matthias; Rüdel, Heinz; Jürling, Heinrich; Severin, Kevin; Hennecke, Stephan; Friesen, Anton; Koschorreck, Jan
Zeitschriftenaufsatz
2019First Survey of Heterobranch Sea Slugs (Mollusca, Gastropoda) from the Island Sangihe, North Sulawesi, Indonesia
Undap, N.; Papu, A.; Schillo, D.; Ijong, F.G.; Kaligis, F.; Lepar, M.; Hertzer, C.; Böhringer, N.; König, G.M.; Schäberle, T.F.; Wägele, H.
Zeitschriftenaufsatz
2019Flow cytometry-based FRET identifies binding intensities in PPARγ1 protein-protein interactions in living cells
Trümper, V.; Knethen, A. von; Preuß, A.; Ermilov, E.; Hackbarth, S.; Kuchler, L.; Gunne, S.; Schäfer, A.; Bornhütter, T.; Vereb, G.; Ujlaky-Nagy, L.; Brüne, B.; Röder, B.; Schindler, M.; Parnham, M.J.; Knape, T.
Zeitschriftenaufsatz
2019Forced degradation studies to identify critical process parameters for the purification of infectious measles virus
Loewe, D.; Häussler, J.; Grein, T.A.; Dieken, H.; Weidner, T.; Salzig, D.; Czermak, P.
Zeitschriftenaufsatz
2019Förderung der Wiederbepflanzung von Windbruchflächen im Sauerland
Drabkin, Dimitri; Weinfurtner, Karlheinz
Aufsatz in Buch
2019Fraunhofer-Institut für Molekularbiologie und Angewandte Oekologie. Jahresbericht 2018
 
Jahresbericht
2019Functional Dominance of CHIP-Mutated Hematopoietic Stem Cells in Patients Undergoing Autologous Transplantation
Ortmann, C.A.; Dorsheimer, L.; Abou-El-Ardat, K.; Hoffrichter, J.; Assmus, B.; Bonig, H.; Scholz, A.; Pfeifer, H.; Martin, H.; Schmid, T.; Brüne, B.; Scheich, S.; Steffen, B.; Riemann, J.; Hermann, S.; Dukat, A.; Bug, G.; Brandts, C.H.; Wagner, S.; Serve, H.; Rieger, M.A.
Zeitschriftenaufsatz
2019Generation of transgenic cell suspension cultures of the model legume Medicago truncatula: A rapid method for Agrobacterium mediated gene transfer
Santos, Rita B.; Pires, Ana Sofia; Hoorn, Renier A.L. van der; Schiermeyer, Andreas; Abranches, Rita
Zeitschriftenaufsatz
2019Genome analysis of the marine bacterium Labrenzia sp. strain 011, a potential protective agent of mollusks
Moghaddam, J.A.; Dávila-Céspedes, A.; Alanjary, M.; Blom, J.; König, G.M.; Schäberle, T.F.
Zeitschriftenaufsatz
2019Genome Editing in Agriculture: Technical and Practical Considerations
Jansing, Julia; Schiermeyer, Andreas; Schillberg, Stefan; Fischer, Rainer; Bortesi, Luisa
Zeitschriftenaufsatz
2019Genomic targeting by recombinase‐mediated cassette exchange in the spotted wing drosophila, Drosophila suzukii
Schetelig, M.F.; Yan, Y.; Zhao, Y.; Handler, A.M.
Zeitschriftenaufsatz
2019Gliotoxin from Aspergillus fumigatus Abrogates Leukotriene B4 Formation through Inhibition of Leukotriene A4 Hydrolase
König, S.; Pace, S.; Pein, H.; Heinekamp, T.; Kramer, J.; Romp, E.; Straßburger, M.; Troisi, F.; Proschak, A.; Dworschak, J.; Scherlach, K.; Rossi, A.; Sautebin, L.; Haeggström, J.Z.; Hertweck, C.; Brakhage, A.A.; Gerstmeier, J.; Proschak, E.; Werz, O.
Zeitschriftenaufsatz
2019GLP-1 levels predict cardiovascular risk in patients with acute myocardial infarction
Kahles, F.; Ruckbeil, M.V.; Mertens, R.W.; Foldenauer, A.C.; Arrivas, M.C.; Moellmann, J.; Lebherz, C.; Biener, M.; Giannitsis, E.; Katus, H.A.; Marx, N.; Lehrke, M.
Abstract
2019GPER1 influences cellular homeostasis and cytostatic drug resistance via influencing long chain ceramide synthesis in breast cancer cells
Wegner, M.-S.; Gruber, L.; Schömel, N.; Trautmann, S.; Brachtendorf, S.; Fuhrmann, D.; Schreiber, Y.; Olesch, C.; Brüne, B.; Geisslinger, G.; Grösch, S.
Zeitschriftenaufsatz
2019High Treatment Satisfaction Of Therapy With Ustekinumab In Patients With Active Psoriatic Arthritis Due To Early And Long-Term Treatment Response And High Tolerability – Results Of The Non-Interventional Study Sustain
Wendler, J.; Wagener, P.; Hamann, F.; Damann, N.; Movshovich, E.; Behrens, F.
Abstract
2019High-Throughput Fluorescence Polarization Assay to Identify Ligands Using Purified G Protein-Coupled Receptor
Heine, P.; Witt, G.; Gilardi, A.; Gribbon, P.; Kummer, L.; Plückthun, A.
Zeitschriftenaufsatz
2019Histone Deacetylation Inhibitors as Therapy Concept in Sepsis. Review
Knethen, A. von; Brüne, B.
Zeitschriftenaufsatz
2019Hitze stabilisiert Malariaimpfstoffkandidaten in komplexen Proteinextrakten
Buyel, J.F.
Zeitschriftenaufsatz
2019Identification and characterization of approved drugs and drug-like compounds as covalent Escherichia coli ClpP inhibitors
Sassetti, E.; Durante Cruz, C.; Tammela, P.; Winterhalter, M.; Augustyns, K.; Gribbon, P.; Windshügel, B.
Zeitschriftenaufsatz
2019Identification of novel agonists by high-throughput screening and molecular modelling of human constitutive androstane receptor isoform 3
Keminer, O.; Windshügel, B.; Essmann, F.; Lee, S.M.L.; Schiergens, T.S.; Schwab, M.; Burk, O.
Zeitschriftenaufsatz
2019Identification of the novel class D β-lactamase OXA-679 involved in carbapenem resistance in Acinetobacter calcoaceticus
Tietgen, M.; Kramer, J.S.; Brunst, S.; Djahanschiri, B.; Wohra, S.; Higgins, P.G.; Weidensdorfer, M.; Riedel-Christ, S.; Pos, K.M.; Gonzaga, A.; Steglich, M.; Nübel, U.; Ebersberger, I.; Proschak, E.; Göttig, S.
Zeitschriftenaufsatz
2019IL-38 Ameliorates Skin Inflammation and Limits IL-17 Production from γδ T Cells
Han, Y.; Mora, J.; Huard, A.; Silva, P. da; Wiechmann, S.; Putyrski, M.; Schuster, C.; Elwakeel, E.; Lang, G.; Scholz, A.; Scholz, T.; Schmid, T.; Bruin, N. de; Billuart, P.; Sala, C.; Burkhardt, H.; Parnham, M.J.; Ernst, A.; Brüne, B.; Weigert, A.
Zeitschriftenaufsatz
2019Imatinib stimulates prostaglandin E2 and attenuates cytokine release via EP4 receptor activation
Bärnthaler, T.; Jandl, K.; Sill, H.; Uhl, B.; Schreiber, Y.; Grill, M.; Thomas, D.; Schicho, R.; Marsche, G.; Frank, S.; Heinemann, A.; Schuligoi, R.
Zeitschriftenaufsatz
2019Immunogenicity assay development and validation for biological therapy as exemplified by ustekinumab
Mojtahed Poor, S.; Ulshöfer, T.; Gabriel, L.A.; Henke, M.; Köhm, M.; Behrens, F.; Geisslinger, G.; Parnham, M.J.; Burkhardt, H.; Schiffmann, S.
Zeitschriftenaufsatz
2019The immunome of soy bean allergy: Comprehensive identification and characterization of epitopes
Kern, Karolin; Havenith, Heide; Delaroque, Nicolas; Rautenberger, Paul; Lehmann, Jörg; Fischer, Markus; Spiegel, Holger; Schillberg, Stefan; Ehrentreich-Förster, Eva; Aurich, Stefanie; Treudler, Regina; Szardenings, Michael
Zeitschriftenaufsatz
2019Impact of Acid-Reducing Agents on Gastrointestinal Physiology and Design of Biorelevant Dissolution Tests to Reflect These Changes
Segregur, D.; Flanagan, T.; Mann, J.; Moir, A.; Karlsson, E.M.; Hoch, M.; Carlile, D.; Sayah-Jeanne, S.; Dressman, J.
Zeitschriftenaufsatz
2019Implantable wireless biometric animal telemetry system: a powerful tool to improve translational sepsis research
Knape, T.; Wilken-Schmitz, A.; Schneider, A.K.; Arne, O.; Schmidt, M.; Götze, L.; Hofmann, M.C.J.; Bruin, N.M.W.J. de; Gerdes, C.; Glenschek-Sieberth, M.; Schmidt, M.V.; Remie, R.; Brill, B.; Parnham, M.J.; Knethen, A. von
Abstract
2019In‐vitro–in‐silico investigation of the negative food effect of zolpidem when administered as immediate‐release tablets
Paraiso, R.L.M.; Watanabe, A.; Andreas, C.J.; Turner, D.; Zane, P.; Dressman, J.
Zeitschriftenaufsatz
2019Influence of methionine residue position on oxidative stability of glucose oxidase from Aspergillus niger
Kovacevic, G.; Ostafe, R.; Fischer, R.; Prodanovic, R.
Zeitschriftenaufsatz
2019Inhibition of the protein kinase IKKepsilon attenuates neuropathic pain in mice
Möser, C.V.; Möller, M.; Fleck, S.C.; Thomas, D.; Geisslinger, G.; Niederberger, E.
Zeitschriftenaufsatz
2019Insektenbiotechnologie: Insekten als Ressource
Vilcinskas, Andreas
Aufsatz in Buch
2019Integrating Drug- and Formulation-Related Properties With Gastrointestinal Tract Variability Using a Product-Specific Particle Size Approach
Cristofoletti, R.; Hens, B.; Patel, N.; Esteban, V.V.; Schmidt, S.; Dressman, J.
Zeitschriftenaufsatz
2019The Integration of Algal Carbon Concentration Mechanism Components into Tobacco Chloroplasts Increases Photosynthetic Efficiency and Biomass
Nölke, G.; Barsoum, M.; Houdelet, M.; Arcalis, E.; Kreuzaler, F.; Fischer, R.; Schillberg, S.
Zeitschriftenaufsatz
2019Iron as a Central Player and Promising Target in Cancer Progression. Review
Jung, M.; Mertens, C.; Tomat, E.; Brüne, B.
Zeitschriftenaufsatz
2019Iron-Dependent Trafficking of 5-Lipoxygenase and Impact on Human Macrophage Activation
Dufrusine, B.; Di Francesco, A.; Oddi, S.; Scipioni, L.; Angelucci, C.B.; D'Addario, C.; Serafini, M.; Häfner, A.-K.; Steinhilber, D.; Maccarrone, M.; Dainese, E.
Zeitschriftenaufsatz
2019Isolation and Identification of Alkaloids from Poisons of Fire Salamanders (Salamandra salamandra)
Knepper, J.; Lüddecke, T.; Preißler, K.; Vences, M.; Schulz, S.
Zeitschriftenaufsatz
2019Konzept zur Implementierung der neuen Umweltqualitätsnormen für prioritäre Stoffe in Fischen (Richtlinie 2013/39/EU). Abschlussbericht
Radermacher, Georg; Fliedner, Annette; Rüdel, Heinz
Bericht
2019Laccase-induced HBT-grafting to milled beech wood reduces unspecific protein adsorption
Jestel, T.; Roth, S.; Heesel, D.; Kress, A.; Fischer, R.; Spiess, A.C.
Zeitschriftenaufsatz
2019Levels, accumulation patterns and retrospective trends of perfluoroalkyl acids (PFAAs) in terrestrial ecosystems over the last three decades
Falk, Sandy; Stahl, Thorsten; Fliedner, Annette; Rüdel, Heinz; Tarricone, Kathrin; Brunn, Hubertus; Koschorreck, Jan
Zeitschriftenaufsatz
2019The Lipid Status in Patients with Ulcerative Colitis: Sphingolipids are Disease-Dependent Regulated
Bazarganipour, S.; Hausmann, J.; Oertel, S.; El-Hindi, K.; Brachtendorf, S.; Blumenstein, I.; Kubesch, A.; Sprinzl, K.; Birod, K.; Hahnefeld, L.; Trautmann, S.; Thomas, D.; Herrmann, E.; Geisslinger, G.; Schiffmann, S.; Grösch, S.
Zeitschriftenaufsatz
2019Long-term outdoor lysimeter study with cerium dioxide nanomaterial
Hoppe, M.; Schlich, K.; Wielinski, J.; Köser, J.; Rückamp, D.; Kaegi, R.; Hund-Rinke, K.
Zeitschriftenaufsatz
2019Loss of function mutation of the Rapid Alkalinization Factor (RALF1)-like peptide in the dandelion Taraxacum koksaghyz entails a high-biomass taproot phenotype
Wieghaus, A.; Prüfer, D.; Schulze Gronover, C.
Zeitschriftenaufsatz
2019Loxapine for treatment of patients with refractory, chemotherapy-induced neuropathic pain: A prematurely terminated pilot study showing efficacy but limited tolerability
Schmiedl, S.; Peters, D.; Schmalz, O.; Mielke, A.; Rossmanith, T.; Diop, S.; Piefke, M.; Thürmann, P.; Schmidtko, A.
Zeitschriftenaufsatz
2019Machine Learning in Human Olfactory Research
Lötsch, J.; Kringel, D.; Hummel, T.
Zeitschriftenaufsatz
2019A machine-learned analysis suggests non-redundant diagnostic information in olfactory subtests
Lötsch, J.; Hummel, T.
Zeitschriftenaufsatz
2019Macrophage HIF‐2α regulates tumor-suppressive Spint1 in the tumor microenvironment
Susen, R.M.; Bauer, R.; Olesch, C.; Fuhrmann, D.C.; Fink, A.F.; Dehne, N.; Jain, A.; Ebersberger, I.; Schmid, T.; Brüne, B.
Zeitschriftenaufsatz
2019Macrophage S1PR1 Signaling Alters Angiogenesis and Lymphangiogenesis During Skin Inflammation
Syed, S.N.; Raue, R.; Weigert, A.; Knethen, A. von; Brüne, B.
Zeitschriftenaufsatz
2019Maintaining hepatic PD-L1 expression improves sepsis survival in a murine polymicrobial sepsis model by tolerizing CTL
Knethen, A. von; Schäfer, A.; Kuchler, L.; Knape, T.; Christen, U.; Hintermann, E.; Fisslthaler, B.; Schröder, K.; Brandes, R.P.; Genz, B.; Abshagen, K.; Pützer, B.M.; Sha, L.K.; Weigert, A.; Syed, S.N.; Schulz, M.; Shah, A.M.; Ernst, A.; Putyrski, M.; Finkelmeier, F.; Pesic, M.; Greten, F.; Hoghardt, M.; Kempf, V.A.J.; Gunne, S.; Parnham, M.J.; Brüne, B.
Abstract
2019Mass Spectrometry-Based Proteomics Approach Characterizes the Dual Functionality of miR-328 in Monocytes
Saul, M.J.; Hegewald, A.B.; Emmerich, A.C.; Ossipova, E.; Vogel, M.; Baumann, I.; Kultima, K.; Lengqivst, J.; Steinhilber, D.; Jakobsson, P.J.
Zeitschriftenaufsatz
2019Melleolides from Honey Mushroom Inhibit 5-Lipoxygenase via Cys159
König, S.; Romp, E.; Krauth, V.; Rühl, M.; Dörfer, M.; Liening, S.; Hofmann, B.; Häfner, A.-K.; Steinhilber, D.; Karas, M.; Garscha, U.; Hoffmeister, D.; Werz, O.
Zeitschriftenaufsatz
2019Members of the endocannabinoid system are distinctly regulated in inflammatory bowel disease and colorectal cancer
Grill, M.; Högenauer, C.; Blesl, A.; Haybaeck, J.; Golob-Schwarzl, N.; Ferreirós, N.; Thomas, D.; Gurke, R.; Trötzmüller, M.; Köfeler, H.C.; Gallè, B.; Schicho, R.
Zeitschriftenaufsatz
2019miR‐574‐5p as RNA decoy for CUGBP1 stimulates human lung tumor growth by mPGES‐1 induction
Saul, M.J.; Baumann, I.; Bruno, A.; Emmerich, A.C.; Wellstein, J.; Ottinger, S.M.; Contursi, A.; Dovizio, M.; Donnini, S.; Tacconelli, S.; Raouf, J.; Idborg, H.; Stein, S.; Korotkova, M.; Savai, R.; Terzuoli, E.; Sala, G.; Seeger, W.; Jakobsson, P.-J.; Patrignani, P.; Suess, B.; Steinhilber, D.
Zeitschriftenaufsatz
2019Molecular Targeting Therapy against EGFR Family in Breast Cancer. Progress and Future Potentials
Maennling, A.E.; Tur, M.K.; Niebert, M.; Klockenbring, Torsten; Zeppernick, F.; Gattenlöhner, S.; Meinhold-Heerlein, I.; Hussain, A.F.
Zeitschriftenaufsatz
2019Monoclonal Antibody AP3 Binds Galactomannan Antigens Displayed by the Pathogens Aspergillus flavus, A. fumigatus, and A. parasiticus
Schubert, M.; Xue, S.; Ebel, F.; Vaggelas, A.; Krylov, V.B.; Nifantiev, N.E.; Chudobova, I.; Schillberg, S.; Nölke, G.
Zeitschriftenaufsatz
2019More yellow more toxic? Sex rather than alkaloid content is correlated with yellow coloration in the fire salamander
Preißler, K.; Gippner, S.; Lüddecke, T.; Krause, E.T.; Schulz, S.; Vences, M.; Steinfartz, S.
Zeitschriftenaufsatz
2019The nanoGRAVUR framework to group (nano)materials for their occupational, consumer, environmental risks based on a harmonized set of material properties, applied to 34 case studies
Wohlleben, W.; Hellack, B.; Nickel, C.; Herrchen, M.; Hund-Rinke, K.; Kettler, K.; Riebeling, C.; Haase, A.; Funk, B.; Kühnel, D.; Göhler, D.; Stintz, M.; Schumacher, C.; Wiemann, M.; Keller, J.; Landsiedel, R.; Brossell, D.; Pitzko, S.; Kuhlbusch, T.A.J.
Zeitschriftenaufsatz
2019Nanomedicines - Tiny particles and big challenges
Marques, M.R.C.; Choo, Q.; Ashtikar, M.; Rocha, T.C.; Bremer-Hoffmann, S.; Wacker, M.G.
Zeitschriftenaufsatz
2019The need for comparative data in spondyloarthritis
Choy, E.; Baraliakos, X.; Behrens, F.; D'Angelo, S.; Vlam, K. de; Kirkham, B.W.; Ostergaard, M.; Schett, G.A.; Rissler, M.; Chaouche-Teyara, K.; Perella, C.
Zeitschriftenaufsatz
2019New insights into the prevalence of depressive symptoms and depression in rheumatoid arthritis
Englbrecht, M.; Alten, R.; Aringer, M.; Baerwald, C.G.; Burkhardt, H.; Eby, N.; Flacke, J.-P.; Fliedner, G.; Henkemeier, U.; Hofmann, M.W.; Kleinert, S.; Kneitz, C.; Krüger, K.; Pohl, C.; Schett, G.; Schmalzing, M.; Tausche, A.-K.; Tony, H.-P.; Wendler, J.
Zeitschriftenaufsatz
2019A new lipoxygenase from the agaric fungus Agrocybe aegerita: Biochemical characterization and kinetic properties
Karrer, D.; Rühl, M.
Zeitschriftenaufsatz
2019A new sesquiterpenoid aminoquinone from an Indonesian marine sponge
Balansa, W.; Mettal, U.; Wuisan, Z.G.; Plubrukarn, A.; Ijong, F.G.; Liu, Y.; Schäberle, T.F.
Zeitschriftenaufsatz
2019New terpenoids from the fermentation broth of the edible mushroom Cyclocybe aegerita
Surup, F.; Hennicke, F.; Sella, N.; Stroot, M.; Bernecker, S.; Pfütze, S.; Stadler, M.; Rühl, M.
Zeitschriftenaufsatz
2019Non-invasive imaging and modeling of liver regeneration after partial hepatectomy
Zafarnia, S.; Mrugalla, A.; Rix, A.; Doleschel, D.; Gremse, F.; Wolf, S.D.; Buyel, J.F.; Albrecht, U.; Bode, J.G.; Kiessling, F.; Lederle, W.
Zeitschriftenaufsatz
2019Novel Approaches to Persistent Pain Therapy
Sisignano, M.; Parnham, M.J.; Geisslinger, G.
Zeitschriftenaufsatz
2019A novel in vivo predictive dissolution testing coupled with a modeling and simulation for hydrogel matrix monolithic extended release oral dosage forms
Kambayashi, A.; Dressman, J.B.
Zeitschriftenaufsatz
2019Nutzung der Erfahrungen und Ergebnisse des Biotamonitorings der Umweltprobenbank für die Umsetzung des WRRL-Fischmonitorings
Fliedner, Annette; Rüdel, Heinz; Koschorreck, Jan
Zeitschriftenaufsatz
2019Omega-3 and -6 fatty acid plasma levels are not associated with liver cirrhosis-associated systemic inflammation
Schwarzkopf, K.M.; Queck, A.; Thomas, D.; Angioni, C.; Cai, C.; Freygang, Y.; Rüschenbaum, S.; Geisslinger, G.; Zeuzem, S.; Welsch, C.; Lange, C.M.
Zeitschriftenaufsatz
2019Opportunities for Successful Stabilization of Poor Glass-Forming Drugs: A Stability-Based Comparison of Mesoporous Silica Versus Hot Melt Extrusion Technologies
Ditzinger, F.; Price, D.J.; Nair, A.; Becker-Baldus, J.; Glaubitz, C.; Dressman, J.; Saal, C.; Kuentz, M.
Zeitschriftenaufsatz
2019Organismen als Produzenten: Produktion von Wertstoffen mithilfe von Mikroorganismen, Algen und Pflanzenzellen
Rasche, Stefan; Schillberg, Stefan; Derwenskus, Felix; Schmid-Staiger, Ulrike; Schließmann, Ursula
Aufsatz in Buch
2019Oxidosqualene cyclase knock-down in latex of taraxacum koksaghyz reduces triterpenes in roots and separated natural rubber
Deenen, N. van; Unland, K.; Prüfer, D.; Schulze Gronover, C.
Zeitschriftenaufsatz
2019Passive equilibrium sampling of hydrophobic organic compounds in homogenised fish tissues of low lipid content
Rojo-Nieto, Elisa; Muz, Melis; Koschorreck, Jan; Rüdel, Heinz; Jahnke, Annika
Zeitschriftenaufsatz
2019Pathogens associated with invasive or introduced insects threaten the health and diversity of native species
Vilcinskas, A.
Zeitschriftenaufsatz
2019PBPK modeling coupled with biorelevant dissolution to forecast the oral performance of amorphous solid dispersion formulations
Kambayashi, A.; Kiyota, T.; Fujiwara, M.; Dressman, J.
Zeitschriftenaufsatz
2019Pflanzenschutzmittel im Grundwasser: Besteht ein Umweltrisiko?
Schäfers, Christoph; Klein, Michael
Konferenzbeitrag
2019Phenotypic Plasticity of Fibroblasts during Mammary Carcinoma Development
Elwakeel, E.; Brüggemann, M.; Fink, A.F.; Schulz, M.H.; Schmid, T.; Savai, R.; Brüne, B.; Zarnack, K.; Weigert, A.
Zeitschriftenaufsatz
2019Phylogeny-Guided Selection of Priority Groups for Venom Bioprospecting
Lüddecke, T.; Vilcinskas, A.; Lemke, S.
Zeitschriftenaufsatz
2019Plant cell packs: A scalable platform for recombinant protein production and metabolic engineering
Rademacher, T.; Sack, M.; Blessing, D.; Fischer, R.; Holland, T.; Buyel, J.
Zeitschriftenaufsatz
2019Plant Molecular Farming - Integration and Exploitation of Side Streams to Achieve Sustainable Biomanufacturing
Buyel, J.F.
Zeitschriftenaufsatz
2019Polypharmacology by Design: A Medicinal Chemist’s Perspective on Multitargeting Compounds
Proschak, E.; Stark, H.; Merk, D.
Zeitschriftenaufsatz
2019Potential biomarkers for persistent and neuropathic pain therapy
Sisignano, M.; Lötsch, J.; Parnham, M.J.; Geisslinger, G.
Zeitschriftenaufsatz
2019Practical advice for selecting or determining trophic magnification factors for application under the European Union water framework directive
Kidd, K.A.; Burkhard, Lawrence P.; Babut, M.; Borgå, Katrine; Muir, Derek C.G.; Perceval, Olivier; Ruedel, Heinz; Woodburn, Kent; Embry, Michelle R.
Zeitschriftenaufsatz
2019The precursor hypothesis of sponge kleptocnidism: Development of nematocysts in Haliclona cnidata sp. nov. (porifera, demospongiae, haplosclerida)
Schellenberg, J.; Reichert, J.; Hardt, M.; Schmidtberg, H.; Kämpfer, P.; Glaeser, S.P.; Schubert, P.; Wilke, T.
Zeitschriftenaufsatz
2019Predicting the Changes in Oral Absorption of Weak Base Drugs Under Elevated Gastric pH Using an In Vitro-In Silico-In Vivo Approach
Kambayashi, A.; Dressman, J.B.
Zeitschriftenaufsatz
2019Predictive PBPK modeling as a tool in the formulation of the drug candidate TMP-001
Nothnagel, L.; Jung, F.; Rossmanith, T.; Thurn, M.; Ashtikar, M.; Geisslinger, G.; Parnham, M.J.; Wacker, M.G.
Zeitschriftenaufsatz
2019Probability Of Achieving Low Disease Activity Or Remission In Subjects With Active Psoriatic Arthritis Treated With Apremilast
Mease, P.J.; Behrens, F.; Gladman, D.D.; Kavanaugh, A.; Brunori, M.; Teng, L.C.; Guerette, B.; Queiro, R.; Ogdie, A.
Abstract
2019Process intensification for an insect antimicrobial peptide elastin-like polypeptide fusion produced in redox-engineered Escherichia coli
Joachim, M.; Maguire, N.; Schäfer, J.; Gerlach, D.; Czermak, P.
Zeitschriftenaufsatz
2019Processing Induced Degradation Routes of Prochloraz in Rapeseed Oil
Göckener, Bernd; Kotthoff, Matthias; Kling, Hans-Willi; Bücking, Mark
Zeitschriftenaufsatz
2019Profiling antimicrobial peptides from the medical maggot Lucilia sericata as potential antibiotics for MDR Gram-negative bacteria
Hirsch, R.; Wiesner, J.; Marker, A.; Pfeifer, Y.; Bauer, A.; Hammann, P.E.; Vilcinskas, A.
Zeitschriftenaufsatz
2019Progranulin deficiency confers resistance to autoimmune encephalomyelitis in mice
Schmitz, K.; Wilken-Schmitz, A.; Vasic, V.; Brunkhorst, R.; Schmidt, M.; Tegeder, I.
Zeitschriftenaufsatz
2019Progress on bringing together raptor collections in Europe for contaminant research and monitoring in relation to chemicals regulation
Movalli, Paola; Duke, Guy; Ramello, Gloria; Dekker, René; Vrezec, Al; Shore, Richard F.; García-Fernández, Antonio; Wernham, Chris; Krone, Oliver; Alygizakis, Nikiforos; Badry, Alexander; Barbagli, Fausto; Biesmeijer, Koos; Boano, Giovanni; Bond, Alexander L.; Choresh, Yael; Bolding Christensen, Jan; Cincinelli, Alessandra; Danielsson, Sara; Dias, Andreia; Dietz, Rune; Eens, Marcel; Espín, Silvia; Eulaers, Igor; Frahnert, Sylke; Fuiz, Tibor I.; Gkotsis, Georgios; Glowacka, Natalia; Gómez-Ramírez, Pilar; Grotti, Marco; Guiraud, Michel; Hosner, Peter; Johansson, Ulf; Jaspers, Veerle L.B.; Kamminga, Pepijn; Koschorreck, Jan; Knopf, Burkhard; Kubin, Eero; LoBrutto, Sabrina; Lourenco, Rui; Martellini, Tania; Martínez-López, Emma; Mateo, Rafael; Nika, Maria-Christina; Nikolopoulou, Varvara; Osborn, Dan; Pauwels, Olivier; Pavia, Marco; Pereira, M. Glória; Rüdel, Heinz; Sanchez-Virosta, Pablo; Slobodnik, Jaroslav; Sonne, Christian; Thomaidis, Nikolaos; Töpfer, Till; Treu, Gabriele; Väinölä, Risto; Valkama,
Zeitschriftenaufsatz
2019Protection of the groundwater against loads of plant protection products: Validation of the new EU-simulation model FO-CUS PELMO 4 for a reliable prediction of the leaching potential of PPP into groundwater
Klein, Michael; Thomas, Kai; Trapp, Matthias; Guerniche, Djamal
Bericht
2019Protection of the groundwater against loads of plant protection products: Validation of the new EU-simulation model FO-CUS PELMO 4 for a reliable prediction of the leaching potential of PPP into groundwater
Klein, Michael; Thomas, Kai; Trapp, Matthias; Guerniche, Djamal
Bericht
2019Proteomic Analysis of the Venom from the Ruby Ant Myrmica rubra and the Isolation of a Novel Insecticidal Decapeptide
Heep, J.; Klaus, A.; Kessel, T.; Seip, M.; Vilcinskas, A.; Skaljac, M.
Zeitschriftenaufsatz
2019Psoriatic Arthritis Impact Of Disease Questionnaire Scores Are Correlated With Disease Activity, As Measured By cDAPSA, In Patients With Psoriatic Arthritis
Orbai, A.M.; Krueger, K.; Behrens, F.; Kiltz, U.; Guerette, B.; Mellars, L.; Brunori, M.; Wollenhaupt, J.
Abstract
2019Quantitative Phosphoproteomics of Selective Autophagy Receptors
Juretschke, T.; Beli, P.; Dikic, I.
Aufsatz in Buch
2019Rating the risks of anticoagulant rodenticides in the aquatic environment: A review
Regnery, Julia; Friesen, Anton; Geduhn, Anke; Göckener, Bernd; Kotthoff, Matthias; Parrhysius, Pia; Petersohn, Eleonora; Reifferscheid, Georg; Schmolz, Erik; Schulz, Robert S.; Schwarzbauer, Jan; Brinke, Marvin
Zeitschriftenaufsatz
2019Ready-to-Use Stocks of Agrobacterium tumefaciens can Simplify Process Development for the Production of Recombinant Proteins by Transient Expression in Plants
Spiegel, H.; Boes, A.; Perales Morales, C.; Rademacher, T.; Buyel, J.F.
Zeitschriftenaufsatz
2019Recent findings of halogenated flame retardants (HFR) in the German and Polar environment
Dreyer, Annekatrin; Neugebauer, Frank; Lohmann, Nina; Rüdel, Heinz; Teubner, Diana; Grotti, Marco; Rauert, Caren; Koschorreck, Jan
Zeitschriftenaufsatz
2019Redox regulation of PPAR gamma in polarized macrophages
Trümper, V.; Wittig, I.; Heidler, J.; Brüne, B.; Knethen, A. von
Abstract
2019Reduced neuropathic pain behavior in mice lacking the cyclic nucleotide-gated channel subunit CNGB1
Kallenborn-Gerhardt, W.; Lu, R.; Petersen, J.J.; Metzner, K.; Kuth, M.S.; Heine, S.; Drees, O.; Paul, M.; Becirovic, E.; Kennel, L.; Flauaus, C.; Gross, T.; Wack, G.; Hohmann, S.W.; Turco, D. del; Biel, M.; Geisslinger, G.; Michalakis, S.; Schmidtko, A.
Abstract
2019A response regulator of the OmpR family is part of the regulatory network controlling the oxidative stress response of Rhodobacter sphaeroides
Zhao, Z.; Peng, T.; Oh, J.-I.; Glaeser, J.; Weber, L.; Li, Q.; Klug, G.
Zeitschriftenaufsatz
2019RNAi targeting of rootworm Troponin I transcripts confers root protection in maize
Fishilevich, E.; Bowling, A.J.; Frey, M.L.F.; Wang, P.-H.; Lo, W.; Rangasamy, M.; Worden, S.E.; Pence, H.E.; Gandra, P.; Whitlock, S.L.; Schulenberg, G.; Knorr, E.; Tenbusch, L.; Lutz, J.R.; Novak, S.; Hamm, R.L.; Schnelle, K.D.; Vilcinskas, A.; Narva, K.E.
Zeitschriftenaufsatz
2019Role of ceramide synthase 2 in G-CSF signaling and G-CSF-R translocation into detergent-resistant membranes
Kurz, J.; Barthelmes, J.; Blum, L.; Ulshöfer, T.; Wegner, M.-S.; Ferreiros, N.; Roser, L.; Geisslinger, G.; Grösch, S.; Schiffmann, S.
Zeitschriftenaufsatz
2019Russell-like bodies in plant seeds share common features with prolamin bodies and occur upon recombinant protein production
Arcalis, E.; Ibl, V.; Hilscher, J.; Rademacher, T.; Avesani, L.; Morandini, F.; Bortesi, L.; Pezzotti, M.; Vitale, A.; Pum, D.; Meyer, T. de; Depicker, A.; Stoger, E.
Zeitschriftenaufsatz
2019SAR Studies and Biological Characterization of a Chromen-4-one Derivative as an Anti- Trypanosoma brucei Agent
Borsari, C.; Santarem, N.; Macedo, S.; Jiménez-Antón, M.D.; Torrado, J.J.; Olías-Molero, A.I.; Corral, M.J.; Tait, A.; Ferrari, S.; Costantino, L.; Luciani, R.; Ponterini, G.; Gul, S.; Kuzikov, M.; Ellinger, B.; Behrens, B.; Reinshagen, J.; Alunda, J.M.; Cordeiro-Da-Silva, A.; Costi, M.P.
Zeitschriftenaufsatz
2019Selective Inactivation of Cancer Drugs by SAMHD1 Provides a Molecular Rationale for Therapeutic Stratification in AML
Schneider, C.; Oellerich, T.; Knecht, K.M.; Thomas, D.; Buzovetsky, O.; Schliemann, C.; Bohnenberger, H.; Angenendt, L.; Hartmann, W.; Wardelmann, E.; Scheich, S.; Comoglio, F.; Wilke, A.; Ströbel, P.; Serve, H.; Geisslinger, G.; Keppler, O.T.; Xiong, Y.; Cinatl, J.
Abstract
2019Selective inactivation of hypomethylating agents by SAMHD1 provides a rationale for therapeutic stratification in AML
Oellerich, T.; Schneider, C.; Thomas, D.; Knecht, K.M.; Buzovetsky, O.; Kaderali, L.; Schliemann, C.; Bohnenberger, H.; Angenendt, L.; Hartmann, W.; Wardelmann, E.; Rothenburger, T.; Mohr, S.; Scheich, S.; Comoglio, F.; Wilke, A.; Ströbel, P.; Serve, H.; Michaelis, M.; Ferreiros, N.; Geisslinger, G.; Xiong, Y.; Keppler, O.T.; Cinatl, J.
Zeitschriftenaufsatz
2019Sensitive and rapid detection of cholera toxin subunit B using magnetic frequency mixing detection
Achtsnicht, S.; Neuendorf, C.; Faßbender, T.; Nölke, G.; Offenhäusser, A.; Krause, H.-J.; Schröper, F.
Zeitschriftenaufsatz
2019Shooting three inflammatory targets with a single bullet: Novel multi-targeting anti-inflammatory glitazones
Elzahhar, P.A.; Alaaeddine, R.; Ibrahim, T.M.; Nassra, R.; Ismail, A.; Chua, B.S.K.; Frkic, R.L.; Bruning, J.B.; Wallner, N.; Knape, T.; Knethen, A. von; Labib, H.; El-Yazbi, A.F.; Belal, A.S.F.
Zeitschriftenaufsatz
2019The significance of comparative genomics in modern evolutionary venomics
Drukewitz, S.H.; Reumont, B.M. von
Zeitschriftenaufsatz
2019Simplified tracking of a soy allergen in processed food using a monoclonal antibody-based sandwich ELISA targeting the soybean 2S albumin gly m 8
Ueberham, Elke; Spiegel, Holger; Havenith, Heide; Rautenberger, Paul; Lidzba, Norbert; Schillberg, Stefan; Lehmann, Jörg
Zeitschriftenaufsatz
2019Sphingosine kinase 2 is a negative regulator of inflammatory macrophage activation
Weigert, A.; Knethen, A. von; Thomas, D.; Faria, I.; Namgaladze, D.; Zezina, E.; Fuhrmann, D.; Petcherski, A.; Meyer zu Heringdorf, D.; Radeke, H.H.; Brüne, B.
Zeitschriftenaufsatz
2019Sphingosine-1-Phosphate and Macrophage Biology - How the Sphinx Tames the Big Eater
Weigert, A.; Olesch, C.; Brüne, B.
Zeitschriftenaufsatz
2019Stability of Biorelevant Media Under Various Storage Conditions
Klumpp, L.; Nagasekar, K.; McCullough, O.; Seybert, A.; Ashtikar, M.; Dressman, J.
Zeitschriftenaufsatz
2019Stimulating brain recovery after stroke using theranostic albumin nanocarriers loaded with nerve growth factor in combination therapy
Feczkó, T.; Piiper, A.; Ansar, S.; Blixt, F.W.; Ashtikar, M.; Schiffmann, S.; Ulshöfer, T.; Parnham, M.J.; Harel, Y.; Israel, L.L.; Lellouche, J.-P.; Wacker, M.G.
Zeitschriftenaufsatz
2019Strategies to Interfere with Tumor Metabolism through the Interplay of Innate and Adaptive Immunity
Mora, J.; Mertens, C.; Meier, J.K.; Fuhrmann, D.C.; Brüne, B.; Jung, M.
Zeitschriftenaufsatz
2019Structural insights into ligand-binding pocket formation in Nurr1 by molecular dynamics simulations
Windshügel, B.
Zeitschriftenaufsatz
2019Structural Insights into the Development of Cycloguanil Derivatives as Trypanosoma brucei Pteridine-Reductase-1 Inhibitors
Landi, G.; Linciano, P.; Borsari, C.; Bertolacini, C.P.; Moraes, C.B.; Cordeiro-da-Silva, A.; Gul, S.; Witt, G.; Kuzikov, M.; Costi, M.P.; Pozzi, C.; Mangani, S.
Zeitschriftenaufsatz
2019Structure optimization of a new class of PPARγ antagonists
Hernandez-Olmos, V.; Knape, T.; Heering, J.; Knethen, A. von; Kilu, W.; Kaiser, A.; Wurglics, M.; Helmstadter, M.; Merk, D.; Schubert-Zsilavecz, M.; Parnham, M.J.; Steinhilber, D.; Proschak, E.
Zeitschriftenaufsatz
2019Surface Acoustic Wave-Based Microfluidic Coagulation Device for Monitoring Anticoagulant Therapy
Harder, S.; Meyer dos Santos, S.; Krozer, V.; Moll, J.
Zeitschriftenaufsatz
2019Surface Activity Profiling (SAP): A potential means of predicting intestinal membrane permeability
Rosenberger, J.; Schmid, K.; Schäfer, K.J.; Dressman, J.
Zeitschriftenaufsatz
2019Symbiont‐mediated chemical defense in the invasive ladybird Harmonia axyridis
Schmidtberg, H.; Shukla, S.P.; Halitschke, R.; Vogel, H.; Vilcinskas, A.
Zeitschriftenaufsatz
2019Synthesis, Biological Evaluation and Structure: Activity Relationships of Diflapolin Analogues as Dual sEH/FLAP Inhibitors
Vieider, L.; Romp, E.; Temml, V.; Fischer, J.; Kretzer, C.; Schoenthaler, M.; Taha, A.; Hernandez-Olmos, V.; Sturm, S.; Schuster, D.; Werz, O.; Garscha, U.; Matuszczak, B.
Zeitschriftenaufsatz
2019Tarantula phylogenomics: A robust phylogeny of deep theraphosid clades inferred from transcriptome data sheds light on the prickly issue of urticating setae evolution
Foley, S.; Lüddecke, T.; Cheng, D.-Q.; Krehenwinkel, H.; Künzel, S.; Longhorn, S.J.; Wendt, I.; Wirth, V. von; Tänzler, R.; Vences, M.; Piel, W.H.
Zeitschriftenaufsatz
2019Targeted insertion of large DNA sequences by homology-directed repair or non-homologous end joining in engineered tobacco BY-2 cells using designed zinc finger nucleases
Schiermeyer, Andreas; Schneider, Katja; Kirchhoff, Janina; Schmelter, Thomas; Koch, Natalie; Ke, Jiang; Herwartz, Denise; Blue, Ryan; Marri, Pradeep; Samuel, Pon; Corbin, David R.; Webb, Steven R.; Gonzalez, Delkin O.; Folkerts, Otto; Fischer, Rainer; Schinkel, Helga; Ainley, W. Michael; Schillberg, Stefan
Zeitschriftenaufsatz
2019Targeted lipidomics reveal derangement of ceramides in major depression and bipolar disorder
Brunkhorst-Kanaan, N.; Klatt-Schreiner, K.; Hackel, J.; Schröter, K.; Trautmann, S.; Hahnefeld, L.; Wicker, S.; Reif, A.; Thomas, D.; Geisslinger, G.; Kittel-Schneider, S.; Tegeder, I.
Zeitschriftenaufsatz
2019Testing effects of pesticides on macroinvertebrate communities in outdoor stream mesocosms using carbaryl as example test item
Beuter, Liesa‑Kristin; Dören, László; Hommen, Udo; Kotthoff, Matthias; Schäfers, Christoph; Ebke, Klaus-Peter
Zeitschriftenaufsatz
2019The therapeutic potential of the insect metalloproteinase inhibitor against infections caused by Pseudomonas aeruginosa
Eisenhardt, M.; Schlupp, P.; Höfer, F.; Schmidts, T.; Hoffmann, D.; Czermak, P.; Pöppel, A.-K.; Vilcinskas, A.; Runkel, F.
Zeitschriftenaufsatz
2019Thromboxane-Induced α-CGRP Release from Peripheral Neurons Is an Essential Positive Feedback Loop in Capsaicin-Induced Neurogenic Inflammation
Tarighi, N.; Menger, D.; Pierre, S.; Kornstädt, L.; Thomas, D.; Ferreiros, N.; Nüsing, R.M.; Geisslinger, G.; Scholich, K.
Zeitschriftenaufsatz
2019Tissue Cytokine IL-33 Modulates the Cytotoxic CD8 T Lymphocyte Activity During Nutrient Deprivation by Regulation of Lineage-Specific Differentiation Programs
Dreis, C.; Ottenlinger, F.M.; Putyrski, M.; Ernst, A.; Huhn, M.; Schmidt, K.G.; Pfeilschifter, J.M.; Radeke, H.H.
Zeitschriftenaufsatz
2019Tolerizing CTL by Sustained Hepatic PD-L1 Expression Provides a New Therapy Approach in Mouse Sepsis
Knethen, A. von; Schäfer, A.; Kuchler, L.; Knape, T.; Christen, U.; Hintermann, E.; Fißlthaler, B.; Schröder, K.; Brandes, R.P.; Genz, B.; Abshagen, K.; Pützer, B.M.; Sha, L.K.; Weigert, A.; Syed, S.N.; Schulz, M.; Shah, A.M.; Ernst, A.; Putyrski, M.; Finkelmeier, F.; Pesic, M.; Greten, F.; Hogardt, M.; Kempf, V.A.J.; Gunne, S.; Parnham, M.J.; Brüne, B.
Zeitschriftenaufsatz
2019Toxins from scratch? Diverse, multimodal gene origins in the predatory robber fly Dasypogon diadema indicate a dynamic venom evolution in dipteran insects
Drukewitz, S.H.; Bokelmann, L.; Undheim, E.A.B.; Reumont, B.M. von
Zeitschriftenaufsatz
2019Transcriptome sequencing of a keystone aquatic herbivore yields insights on the temperature-dependent metabolism of essential lipids
Windisch, Heidrun S.; Fink, Patrick
Zeitschriftenaufsatz
2019Transmission of a protease-secreting bacterial symbiont among pea aphids via host plants
Skaljac, M.; Vogel, H.; Wielsch, N.; Mihajlovic, S.; Vilcinskas, A.
Zeitschriftenaufsatz
2019Tribolium castaneum as a whole‐animal screening system for the detection and characterization of neuroprotective substances
Brandt, A.; Joop, G.; Vilcinskas, A.
Zeitschriftenaufsatz
2019TRPA1 Sensitization Produces Hyperalgesia to Heat but not to Cold Stimuli in Human Volunteers
Weyer-Menkhoff, I.; Lötsch, J.
Zeitschriftenaufsatz
2019Tunicate-associated bacteria show a great potential for the discovery of antimicrobial compounds
Ayuningrum, D.; Liu, Y.; Riyanti; Sibero, M.T.; Kristiana, R.; Asagabaldan, M.A.; Wuisan, Z.G.; Trianto, A.; Radjasa, O.K.; Sabdono, A.; Schaberle, T.F.
Zeitschriftenaufsatz
2019Tuning Nuclear Receptor Selectivity of Wy14,643 towards Selective Retinoid X Receptor Modulation
Pollinger, J.; Gellrich, L.; Schierle, S.; Kilu, W.; Schmidt, J.; Kalinowsky, L.; Ohrndorf, J.; Kaiser, A.; Heering, J.; Proschak, E.; Merk, D.
Zeitschriftenaufsatz
2019Two-step production of neofructo-oligosaccharides using immobilized heterologous aspergillus terreus 1f-fructosyltransferase expressed in Kluyveromyces lactis and native Xanthophyllomyces dendrorhous G6-fructosyltransferase
Burghardt, J.P.; Baas, M.; Gerlach, D.; Czermak, P.
Zeitschriftenaufsatz
2019Uncovering mechanisms of rubber biosynthesis in Taraxacum koksaghyz - role of cis-prenyltransferase-like 1 protein
Niephaus, E.; Müller, B.; Deenen, N. van; Lassowskat, I.; Bonin, M.; Finkemeier, I.; Prüfer, D.; Schulze Gronover, C.
Zeitschriftenaufsatz
2019A validated LC-MS/MS method for the determination of homocysteic acid in biological samples
Gurke, R.; Schmidt, D.; Thomas, D.; Fleck, S.C.; Geisslinger, G.; Ferreiros, N.
Zeitschriftenaufsatz
2019Verhalten nanomaterialhaltiger Schlacken und Aschen aus Müllverbrennung und Klärschlammverbrennung
Oischinger, Jürgen; Meisterjahn, Boris
Vortrag
2019Versorgungssituation von Patienten mit ankylosierender Spondylitis und Psoriasisarthritis in Deutschland
Braun, J.; Schwarting, A.; Hammel, L.; Legeler, C.; Wimmer, P.; Färber, L.; Behrens, F.
Zeitschriftenaufsatz
2019Visualizing ubiquitination in mammalian cells
Wijk, S.J. van; Fulda, S.; Dikic, I.; Heilemann, M.
Zeitschriftenaufsatz
2019Zafirlukast Is a Dual Modulator of Human Soluble Epoxide Hydrolase and Peroxisome Proliferator-Activated Receptor γ
Göbel, T.; Diehl, O.; Heering, J.; Merk, D.; Angioni, C.; Wittmann, S.K.; Buscato, E. la; Kottke, R.; Weizel, L.; Schader, T.; Maier, T.J.; Geisslinger, G.; Schubert-Zsilavecz, M.; Steinhilber, D.; Proschak, E.; Kahnt, A.S.
Zeitschriftenaufsatz