Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2019BAL cell gene expression is indicative of outcome and airway basal cell involvement in idiopathic pulmonary fibrosis
Prasse, Antje; Binder, Harald; Schupp, Jonas C.; Kayser, Gian; Bargagli, Elena; Jäger, Benedikt; Hess, Moritz; Rittinghausen, Susanne; Vuga, Louis; Lynn, Heather; Violette, Shelia; Jung, Birgit; Quast, Karsten; Vanaudenaerde, Bart; Xu, Yan; Hohlfeld, Jens M.; Krug, Norbert; Herazo-Maya, Jose D.; Rottoli, Paola; Wuyts, Wim A.; Kaminski, Naftali
Journal Article
2019Cabin air quality – Quantitative comparison of volatile air contaminants at different flight phases during 177 commercial flights
Schuchardt, S.; Koch, W.; Rosenberger, W.
Journal Article
2019The clinical course of idiopathic pulmonary fibrosis and its association to quality of life over time
Kreuter, M.; Swigris, J.; Pittrow, D.; Geier, S.; Klotsche, J.; Prasse, A.; Wirtz, H.; Koschel, D.; Andreas, S.; Claussen, M.; Grohé, C.; Wilkens, H.; Hagmeyer, L.; Skowasch, D.; Meyer, J.F.; Kirschner, J.; Gläser, S.; Kahn, N.; Welte, T.; Neurohr, C.; Schwaiblmair, M.; Held, M.; Bahmer, T.; Oqueka, T.; Frankenberger, M.; Behr, J.
Journal Article
2019Differentiation of Aneugens and Clastogens in the In Vitro Micronucleus Test by Kinetochore Scoring Using Automated Image Analysis
Wilde, S.; Queisser, N.; Holz, C.; Raschke, M.; Sutter, A.
Journal Article
2019Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation
Jevnikar, Z.; Östling, J.; Ax, E.; Calven, J.; Thörn, K.; Israelsson, E.; Öberg, L.; Singhania, A.; Lau, L.C.K.; Wilson, S.J.; Ward, J.A.; Chauhan, A.; Sousa, A.R.; Meulder, B. de; Loza, M.J.; Baribaud, F.; Sterk, P.J.; Chung, K.F.; Sun, K.; Guo, Y.; Adcock, I.M.; Payne, D.; Dahlen, B.; Chanez, P.; Shaw, D.E.; Krug, Norbert; Hohlfeld, Jens M.; Sandström, T.; Djukanovic, R.; James, A.; Hinks, T.S.C.; Howarth, P.H.; Vaarala, O.; Geest, M. van; Olsson, H.; Adcock, I.M.; Ahmed, H.; Auffray, C.; Bakke, P.; Bansal, A.T.; Baribaud, F.; Bates, S.; Bel, E.H.; Bigler, J.; Bisgaard, H.; Boedigheimer, M.J.; Bonnelykke, K.; Brandsma, J.; Brinkman, P.; Bucchioni, E.; Burg, D.; Bush, A.; Caruso, M.; Chaiboonchoe, A.; Chanez, P.; Chung, F.K.; Compton, C.H.; Corfield, J.; D'Amico, A.; Dahlen, S.E.; De Meulder, B.; Djukanovic, R.; Erpenbeck, V.J.; Erzen, D.; Fichtner, K.; Fitch, N.; Fleming, L.J.; Formaggio, E.; Fowler, S.J.; Frey, U.; Gahlemann, M.; Geiser, T.; Goss, V.; Guo, Y.; Hashimoto, S.; Haughney, J.; Hedlin,
Journal Article
2019Identification and quantification of synthetic cannabinoids in 'spice-like' herbal mixtures: Update of the German situation in summer 2018
Ernst, L.; Langer, N.; Bockelmann, A.; Salkhordeh, E.; Beuerle, T.
Journal Article
2019Mapping of regional lung microstructural parameters using hyperpolarized 129Xe dissolved‐phase MRI in healthy volunteers and patients with chronic obstructive pulmonary disease
Kern, A.L.; Gutberlet, M.; Voskrebenzev, A.; Klimes, F.; Rotärmel, A.; Wacker, F.; Hohlfeld, J.M.; Vogel-Claussen, J.
Journal Article
2019Microfluidic enrichment, isolation and characterization of disseminated melanoma cells from lymph node samples
Weidele, Kathrin; Stojanović, Nataša; Feliciello, Giancarlo; Markiewicz, Aleksandra; Scheitler, Sebastian; Alberter, Barbara; Renner, Philipp; Haferkamp, Sebastian; Klein, Christoph A.; Polzer, Bernhard
Journal Article
2019MicroRNA-144-3p targets relaxin/insulin-like family peptide receptor 1 (RXFP1) expression in lung fibroblasts from patients with idiopathic pulmonary fibrosis
Bahudhanapati, H.; Tan, J.; Dutta, J.A.; Strock, S.B.; Sembrat, J.; Alvarez, D.; Rojas, M.; Jäger, B.; Prasse, A.; Zhang, Y.; Kass, D.J.
Journal Article
2019The rat bone marrow micronucleus test: Statistical considerations on historical negative control data
Igl, B.-W.; Bitsch, A.; Bringezu, F.; Chang, S.; Dammann, M.; Frötschl, R.; Harm, V.; Kellner, R.; Krzykalla, V.; Lott, J.; Nern, M.; Pfuhler, S.; Queisser, N.; Schulz, M.; Sutter, A.; Vaas, L.; Vonk, R.; Zellner, D.; Ziemann, C.
Journal Article
2019Regional investigation of lung function and microstructure parameters by localized 129Xe chemical shift saturation recovery and dissolved‐phase imaging
Kern, A.L.; Gutberlet, M.; Qing, K.; Voskrebenzev, A.; Klimes, F.; Kaireit, T.F.; Czerner, C.; Biller, H.; Wacker, F.; Ruppert, K.; Hohlfeld, J.M.; Vogel-Claussen, J.
Journal Article
2019Repeatability of Regional Lung Ventilation Quantification Using Fluorinated (19F) Gas Magnetic Resonance Imaging
Gutberlet, M.; Kaireit, T.F.; Voskrebenzev, A.; Kern, A.L.; Obert, A.; Wacker, F.; Hohlfeld, J.M.; Vogel-Claussen, J.
Journal Article
2018Acute inhalation toxicity in vitro and ex vivo test battery prior to regulatory OECD 403 studies
Schwarz, Katharina; Hansen, Tanja; Ritter, Detlef; Walter, Dorothee; Knebel, Jan
Abstract
2018Air-liquid interface in vitro models for respiratory toxicology research: Consensus workshop and recommendations
Lacroix, Ghislaine; Koch, Wolfgang; Ritter, Detlef; Gutleb, Arno C.; Larsen, Søren Thor; Loret, Thomas; Zanetti, Filippo; Constant, Samuel; Chortarea, Savvina; Rothen-Rutishauser, Barbara M.; Hiemstra, Pieter S.; Frejafon, Emeric; Hubert, Philippe; Gribaldo, Laura; Kearns, Peter; Aublant, Jean-Marc; Diabaté, Silvia; Weiss, Carsten; Groot, Antoinette de; Kooter, Ingeborg
Journal Article
2018Airway and systemic inflammatory responses to ultrafine carbon black particles and ozone in older healthy subjects
Holz, Olaf; Heusser, Karsten; Müller, Meike; Windt, Horst; Schwarz, Katharina; Schindler, Christoph; Tank, Jens; Hohlfeld, Jens M.; Jordan, Jens
Journal Article
2018Alpha-1 antitrypsin inhibits ATP-mediated release of interleukin-1β via CD36 and nicotinic acetylcholine receptors
Siebers, Kathrin; Fink, Bijan; Zakrzewicz, Anna; Agné, Alisa; Richter, Katrin; Konzok, Sebastian; Hecker, Andreas; Zukunft, Sven; Küllmar, Mira; Klein, Jochen; McIntosh, J. Michael; Timm, Thomas; Sewald, Katherina; Padberg, Winfried; Aggarwal, Nupur; Chamulitrat, Walee; Santoso, Sentot; Xia, Wendy; Janciauskiene, Sabina; Grau, Veronika
Journal Article
2018An apoplastic peptide activates salicylic acid signalling in maize
Ziemann, Sebastian; Linde, Karina van der; Lahrmann, Urs; Acar, Beyda; Kaschani, Farnusch; Colby, Tom; Kaiser, Markus; Ding, Yezhang; Schmelz, Eric; Huffaker, Alisa; Holton, Nicholas; Zipfel, Cyril; Doehlemann, Gunther
Journal Article
2018The application of new HARD-descriptor available from the CORAL software to building up NOAEL models
Toropova, Alla P.; Toropov, Andrey A.; Marzo, Marco; Escher, Sylvia E.; Dorne, Jean Lou; Georgiadis, Nikolaos; Benfenati, Emilio
Journal Article
2018Approaches on MWCNT diameters and its relation to tumor development
Schwotzer, Daniela; Meyer-Plath, Asmus; Rittinghausen, Susanne; Creutzenberg, Otto H.; Leonhardt, Albrecht; Schaudien, Dirk
Abstract
2018Assessment of the cytotoxic and immunomodulatory effects of substances in human precision-cut lung slices
Neuhaus, Vanessa; Danov, Olga; Konzok, Sebastian; Obernolte, Helena; Dehmel, Susann; Braubach, Peter; Jonigk, Danny; Fieguth, Hans-Gerd; Zardo, Patrick; Warnecke, Gregor; Martin, Christian; Braun, Armin; Sewald, Katherina
Journal Article
2018Atemgesteuerte Applikation von pulverförmigen Aerosol bei der Beatmung oder Atemunterstützung eines Patienten
Iwaschenko, Peter; Pohlmann, Gerhard; Wiegandt, Felix
Patent
2018B cells control maternofetal priming of allergy and tolerance in a murine model of allergic airway inflammation
Happle, Christine; Jirmo, Adan Chari; Meyer-Bahlburg, Almut; Habener, Anika; Hoymann, Heinz-Gerd; Hennig, Christian; Skuljec, Jelena; Hansen, Gesine
Journal Article
2018Best practice approach for assessment of microchip-associated tumors in preclinical safety studies: Position of the Registry of Industrial Toxicology Animal-data (RITA)
Lapp, Stefanie; Bube, Axel; Colbatzky, Florian A.; Ernst, Heinrich; Kellner, Rupert; Nolte, Thomas; Rinke, Matthias
Journal Article
2018Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections
Ackermann, Mania; Kempf, Henning; Hetzel, Miriam; Hesse, Christina; Hashtchin, Anna Rafiei; Brinkert, Kerstin; Schott, Juliane Wilhelmine; Haake, Kathrin; Kühnel, Mark Philipp; Glage, Silke; Figueiredo, Constanca; Jonigk, Danny; Sewald, Katherina; Schambach, Axel; Wronski, Sabine; Moritz, Thomas; Martin, Ulrich; Zweigerdt, Robert; Munder, Antje; Lachmann, Nico
Journal Article
2018Breath volatile organic compounds of lung transplant recipients with and without chronic lung allograft dysfunction
Küppers, L.; Holz, Olaf; Schuchardt, Sven; Gottlieb, J.; Fuge, J.; Greer, M.; Hohlfeld, Jens M.
Journal Article
2018Carbon nanotube-silicone rubber on active thin-film implants
Behrens, Ailke; Foremny, Katharina; Doll, Theodor
Journal Article
2018Cerium oxide and barium sulfate nanoparticle inhalation affects gene expression in alveolar epithelial cells type II
Schwotzer, Daniela; Niehof, Monika; Schaudien, Dirk; Kock, Heiko; Hansen, Tanja; Dasenbrock, Clemens; Creutzenberg, Otto H.
Journal Article
2018Challenges in characterizing the environmental fate and effects of carbon nanotubes and inorganic nanomaterials in aquatic systems
Laux, Peter; Riebeling, Christian; Booth, Andy M.; Brain, Joseph D.; Brunner, Josephine; Cerrillo, Cristina; Creutzenberg, Otto H.; Estrela-Lopis, Irina; Gebel, Thomas; Johanson, Gunnar; Jungnickel, Harald; Kock, Heiko; Tentschert, Jutta; Tlili, Ahmed; Schäffer, Andreas; Sips, Adriënne J.A.M.; Yokel, Robert A.; Luch, Andreas
Journal Article
2018Characterization of human precision cut liver slices by various viability andfunctional parameters during 24 hour culture
Elenschneider, Leroy; Knebel, Jan; Braun, Armin; Fangmann, J.; Hansen, Tanja
Abstract
2018A combination of in-vitro and ex-vivo test models as an upstream alternative to regulatory OECD 403 animal studies
Walter, Dorothee; Ritter, Detlef; Knebel, Jan; Schwarz, Katharina; Hansen, Tanja
Abstract
2018Comparative proteomic analysis of hepatic effects induced by nanosilver, silver ions and nanoparticle coating in rats
Juling, Sabine; Böhmert, Linda; Lichtenstein, Dajana; Oberemm, Axel; Creutzenberg, Otto H.; Thünemann, Andreas F.; Braeuning, Albert; Lampen, Alfonso
Journal Article
2018Comparison of quantitative regional ventilation‐weighted fourier decomposition MRI with dynamic fluorinated gas washout MRI and lung function testing in COPD patients
Kaireit, Till F.; Gutberlet, Marcel; Voskrebenzev, Andreas; Freise, Julia; Welte, Tobias; Hohlfeld, Jens M.; Wacker, Frank; Vogel-Claussen, Jens
Journal Article
2018A comprehensive way to rate sputum quality in clinical trials
Pedersen, Frauke; Zissler, U.; Watz, Henrik; Rabe, Klaus F.; Hohlfeld, Jens M.; Holz, Olaf
Abstract
2018A computational framework for complex disease stratification from multiple large-scale datasets
Meulder, Bertrand de; Lefaudeux, Diane; Bansal, Aruna T.; Mazein, Alexander; Chaiboonchoe, Amphun; Ahmed, Hassan; Balaur, Irina; Saqi, Mansoor; Pellet, Johann; Ballereau, Stephane; Lemonnier, Nathanaël; Sun, Kai; Pandis, Ioannis; Yang, Xian; Batuwitage, Manohara; Kretsos, Kosmas; Eyll, Jonathan van; Bedding, Alun; Davison, Timothy; Dodson, Paul; Larminie, Christopher; Postle, Anthony; Corfield, Julie; Djukanović, Ratko; Chung, Kian Fan; Adcock, Ian M.; Guo, Yi-Ke; Sterk, Peter J.; Manta, Alexander; Rowe, Anthony; Baribaud, Frédéric; Auffray, Charles; Badorrek, Philipp; Faulenbach, Cornelia; Braun, Armin; Hohlfeld, Jens; Krug, Norbert
Journal Article
2018Cytotoxicity testing of therapeutic nanosystems for pulmonary infection using an air-lifted interphase in-vitro test system
Knebel, Jan W.; Ritter, Detlef; Niehof, Monika; Hansen, Tanja; Strandh, M.; Falciani, C.; Flores, M.; Welscher, Y. te; Nostrum, C. van; Gracia, R.; Marradi, M.; Loinaz, I.
Abstract
2018Development and evaluation of an in vitro test system for toxicity screening of aerosols released from consumer products and first application to aerosols from a hair straightening process
Ritter, Detlef; Bitsch, Annette; Elend, Manfred; Schuchardt, Sven; Hansen, Tanja; Brodbeck, Carsten; Knebel, Jan; Fuchs, Anne; Gronewold, Claas; Fautz, Rolf
Journal Article
2018Development of a novel scoring system for identifying emerging chemical risks in the food chain
Oltmanns, J.; Licht, O.; Bitsch, A.; Bohlen, M.-L.; Escher, S.E.; Silano, V.; Macleod, M.; Serafimova, R.; Kass, G.E.N.; Merten, C.
Journal Article
2018Development of an updated carcinogenicity potency database and analysis of thresholds of toxicological concern
Cronin, M.T.D.; Belfield, S.; Escher, Sylvia E.; Firman, J.; Liu, J.; Marsaux, C.; Mostrag-Szlichtyng, A.; Przybylak, K.; Rathman, J.; Tarkhov, Aleksey; Yang, C.
Abstract
2018Dezellularisierte Implantathüllen
Doll, Theodor; Pohlmann, Gerhard; Sieghorst, Jan
Patent
2018Diagnostic pathology of early systemic cancer: ERBB2 gene amplification in single disseminated cancer cells determines patient survival in operable esophageal cancer
Hoffmann, Martin; Pasch, Sophie; Schamberger, Thomas; Maneck, Matthias; Möhlendick, Birte; Schumacher, Sarah; Brockhoff, Gero; Knoefel, Wolfram Trudo; Izbicki, Jakob; Polzer, Bernhard; Stoecklein, Nikolas H.; Klein, Christoph A.
Journal Article
2018Effect of lung deflation with indacaterol plus glycopyrronium on ventricular filling in patients with hyperinflation and COPD (CLAIM): A double-blind, randomised, crossover, placebo-controlled, single-centre trial
Hohlfeld, Jens M.; Vogel-Claussen, Jens; Biller, Heike; Berliner, Dominik; Berschneider, Korbinian; Tillmann, Hanns-Christian; Hiltl, Simone; Bauersachs, Johann; Welte, Tobias
Journal Article
2018Engystol reduces onset of experimental respiratory syncytial virus-induced respiratory inflammation in mice by modulating macrophage phagocytic capacity
Wronski, Sabine; Dannenmaier, Julia; Schild, Sabine; Macke, Olaf; Müller, Laura; Burmeister, Yvonne; Seilheimer, Bernd; Müller, Meike
Journal Article
2018Enhanced oxidative stress in smoking and ex-smoking severe asthma in the U-BIOPRED cohort
Emma, Rosalia; Bansal, Aruna T.; Kolmert, Johan; Wheelock, Craig E.; Dahlén, Sven-Erik; Loza, Matthew J.; Meulder, Bertrand de; Lefaudeux, Diane; Auffray, Charles; Dahlén, Barbro; Bakke, Per S.; Chanez, Pascal; Fowler, Stephen J.; Horvath, Ildiko; Montuschi, Paolo; Krug, Norbert; Sanak, Marek; Sandström, Thomas; Shaw, Dominick E.; Fleming, Louise J.; Djukanovic, Ratko; Howarth, Peter H.; Singer, Florian; Sousa, Ana R.; Sterk, Peter J.; Corfield, Julie; Pandis, Ioannis; Chung, Kian F.; Adcock, Ian M.; Lutter, René; Fabbella, Lorena; Caruso, Massimo
Journal Article
2018Entwicklung einer Logistikkonzeption für eine dezentrale Fertigung von medizinischen Prüfprodukten
Abt, Felix
: Kopp, Harald (Betreuer); Diemar, Ute (Betreuer)
Master Thesis
2018EUToxRisk case studies: new approach methodologies in read-across
Escher, Sylvia E.
Abstract
2018Evaluation of the dose-response and fate in the lung and pleura of chrysotile containing brake dust compared to chrysotile or crocidolite asbestos in a 28 day inhalation toxicology study
Tóth, B.; Bernstein, David M.; Rogers, R.A.; Kunzendorf, Peter; Ernst, Heinrich
Abstract
2018Evaluation of the dose-response and fate in the lung and pleura of chrysotile containing brake dust compared to chrysotile or crocidolite asbestos in a 28-day inhalation toxicology study
Bernstein, D.M.; Tóth, B.; Rogers, R.A.; Kunzendorf, P.; Ernst, Heinrich
Abstract
2018Evaluation of the dose-response and fate in the lung and pleura of chrysotile-containing brake dust compared to chrysotile or crocidolite asbestos in a 28-day quantitative inhalation toxicology study
Bernstein, D.M.; Tóth, B.; Rogers, R.A.; Sepulveda, R.; Kunzendorf, P.; Phillips, J.I.; Ernst, Heinrich
Journal Article
2018Evaluierung der ökotoxikologischen Risikobewertung für genmodifizierte Arzneimittel
Weber, Elena
: Illing, Gerhard (1. Gutachter); Weigt, Henning (2. Gutachter)
Master Thesis
2018EXITOX-II: Development of an animal free testing strategy for the risk assessment of inhalable compounds
Escher, Sylvia E.; Tluczkiewicz, Inga; Hansen, Tanja; Niehof, Monika; Knebel, Jan; Ritter, Detlef; Danov, Olga; Obernolte, Helena; Schramm, Sinja-Fee; Koschmann, Jeannette; Kel, Alexander; Wingender, Edgar; Meckbach, Cornelia; Boomgarden, Wolfgang; Sewald, Katherina
Abstract
2018Flexible high density active neural implants combining a distributed multiplexing transceiver architecture with biocompatible technology
Marcoleta, Juan Pablo; Nogueira, Waldo; Froriep, Ulrich Paul; Doll, Theodor
Journal Article
2018Fraunhofer-Institut für Toxikologie und Experimentelle Medizin. Leistungen und Ergebnisse. Jahresbericht 2017
: Nastevska, Cathrin (Red.); Schlemminger, Karin (Übers.)
Annual Report
2018Fraunhofer-Institute for Toxicology and Experimental Medicine. Performance and Results. Annual Report 2017
: Nastevska, Cathrin (Red.); Schlemminger, Karin (Übers.)
Annual Report
2018Free-breathing dynamic (19)F gas MR imaging for mapping of regional lung ventilation in patients with COPD
Gutberlet, Marcel; Kaireit, Till F.; Voskrebenzev, Andreas; Lasch, Florian; Freise, Julia; Welte, Tobias; Wacker, Frank; Hohlfeld, Jens M.; Vogel-Claussen, Jens
Journal Article
2018A GATA3-specific DNAzyme attenuates sputum eosinophilia in eosinophilic COPD patients: A feasibility randomized clinical trial
Greulich, Timm; Hohlfeld, Jens M.; Neuser, Petra; Lueer, Katrin; Klemmer, Andreas; Schade-Brittinger, Carmen; Harnisch, Susanne; Garn, Holger; Renz, Harald; Homburg, Ursula; Renz, Jonas; Kirsten, Anne; Pedersen, Frauke; Müller, Meike; Vogelmeier, Claus F.; Watz, Henrik
Journal Article
2018Gene network analysis of interstitial macrophages after treatment with induced pluripotent stem cells secretome (iPSC-cm) in the bleomycin injured rat lung
Tamò, Luca; Simillion, Cedric; Hibaoui, Yousse; Feki, Anis; Gugger, Mathias; Prasse, Antje; Jäger, Benedikt; Goldmann, Torsten; Geiser, Thomas; Gazdhar, Amiq
Journal Article
2018Genetic alterations driving metastatic colony formation are acquired outside of the primary tumour in melanoma
Werner-Klein, Melanie; Scheitler, Sebastian; Hoffmann, Martin; Hodak, Isabelle; Dietz, Klaus; Lehnert, Petra; Naimer, Veronika; Polzer, Bernhard; Treitschke, Steffi; Werno, Christian; Markiewicz, Aleksandra; Weidele, Kathrin; Czyz, Zbigniew; Hohenleutner, Ulrich; Hafner, Christian; Haferkamp, Sebastian; Berneburg, Mark; Rümmele, Petra; Ulmer, Anja; Klein, Christoph A.
Journal Article
2018Genotoxic and mutagenic potential of camphorquinone in L5178/TK(+/-) mouse lymphoma cells
Volk, Joachim; Ziemann, Christina; Leyhausen, Gabriele; Geurtsen, Werner
Journal Article
2018German guideline for idiopathic pulmonary fibrosis - update on pharmacological therapies 2017
Behr, Jürgen; Günther, Andreas; Bonella, Francesco; Geißler, Klaus; Koschel, Dirk; Kreuter, Michael; Prasse, Antje; Schönfeld, Nicolas; Sitter, Helmut; Müller-Quernheim, Joachim; Costabel, Ulrich
Journal Article
2018High throughput adaptive stress response pathway activation to support read across of valproic acid analogue-induced liver steatosis
Vrijenhoek, N.G.; Gräpel, Rabea; Wink, S.; Escher, Sylvia E.; Water, Bob van de
Abstract
2018High-throughput microscopy of adaptive stress response pathway activation by steatosis-inducing valproic acid analogues
Vrijenhoek, N.G.; Gräpel, Rabea; Escher, Sylvia E.; Water, Bob van de
Abstract
2018Human airway mucus alters susceptibility of Pseudomonas aeruginosa biofilms to tobramycin, but not colistin
Müller, Laura; Murgia, Xabier; Siebenburger, Lorenz; Börger, Carsten; Schwarzkopf, Konrad; Sewald, Katherina; Häussler, Susanne; Braun, Armin; Lehr, Claus-Michael; Hittinger, Marius; Wronski, Sabine
Journal Article
2018Human lung tissue provides highly relevant data about efficacy of new anti-asthmatic drugs
Danov, Olga; Jiménez Delgado, Sharon Melissa; Obernolte, Helena; Seehase, Sophie; Dehmel, Susann; Braubach, Peter; Fieguth, Hans-Gerd; Matschiner, Gabriele; Fitzgerald, Mary; Jonigk, Danny; Knauf, Sascha; Pfennig, Olaf; Warnecke, Gregor; Wichmann, Judy; Braun, Armin; Sewald, Katherina
Journal Article
2018Human teratoma-derived hematopoiesis is a highly polyclonal process supported by human umbilical vein endothelial cells
Philipp, Friederike; Selich, Anton; Rothe, Michael; Hoffmann, Dirk; Rittinghausen, Susanne; Morgan, Michael A.; Klatt, Denise; Glage, Silke; Lienenklaus, Stefan; Neuhaus, Vanessa; Sewald, Katherina; Braun, Armin; Schambach, Axel
Journal Article
2018ICONS - Integrated testing strategy for mechanistically assessing the respiratory toxicity of functionalized MWCNTs - Comparative in vitro investigations
Ziemann, Christina; Reamon-Buettner, Stella Marie; Lison, Dominique; Bonner, J.C.; Brûle, Sybille van den; Simon, S.; Creutzenberg, Otto H.
Abstract
2018An immune cell spray (ICS) formulation allows for the delivery of functional monocyte/macrophages
Beneke, Valerie; Küster, Fennja; Neehus, Anna-Lena; Hesse, Christina; Lopez-Rodriguez, Elena; Haake, Kathrin; Rafiei Hashtchin, Anna; Schott, Juliane Wilhelmine; Walter, Dorothee; Braun, Armin; Wolkers, Willem F.; Ackermann, Mania; Lachmann, Nico
Journal Article
2018Impaired IFNγ-signaling and mycobacterial clearance in IFNγR1-deficient human iPSC-derived macrophages
Neehus, Anna-Lena; Lam, Jenny; Haake, Kathrin; Merkert, Sylvia; Schmidt, Nico; Mucci, Adele; Ackermann, Mania; Schubert, Madline; Happle, Christine; Kühnel, Mark Philipp; Blank, Patrick; Philipp, Friederike; Goethe, Ralph; Jonigk, Danny; Martin, Ulrich; Kalinke, Ulrich; Baumann, Ulrich; Schambach, Axel; Roesler, Joachim; Lachmann, Nico
Journal Article
2018Importance of the IL-1 axis in haemophilus influenzae-stimulated M1 macrophages driving transepithelial signaling
Mang, Samuel; Braun, Armin; Pairet, Nicolas; Lamb, David J.
Journal Article
2018Ein importierter Fall von feliner Leishmaniose in Deutschland und eine Literaturübersicht zur felinen Leishmaniose
Zind, Laura; Troyke, Reiner; Turban, Kathrin; Schaudien, Dirk; Baumgärtner, Wolfgang; Hansmann, Florian
Journal Article
2018In depth analysis of selected cosmetic ingredients from the SkinAB database
Schmeinck, Sina; Bitsch, Annette; Genth, Harald
Abstract
2018In silico prediction of DILI: Extraction of histopathology data from preclinical toxicity studies of the eTOX database for new in silico models of hepatotoxicity
Amberg, A.; Anger, L.; Stolte, M.; Hemmerich, J.; Matter, H.; Fisk, L.; Tluczkiewicz, Inga; Pinto-Gil, K.; López-Massaguer, O.; Pastor, M.
Abstract
2018In silico prediction of DILI: extraction of histopathology data from preclinical toxicity studies of the eTOX database for new in silico models of hepatotoxicity
Sullivan, K.; Baker, N.; Cochrane, S.; Enoch, Steven J.; Ezendam, Janine; Patlewicz, G.; Roggen, Erwin L.; Settivari, R.; Sewald, Katherina
Abstract
2018In vitro to in vivo extrapolation of valproic acid hepatotoxicity: A biokinetic and physiologically based toxicokinetic informed approach
Fisher, C.P.; Hatley, O.; Vugt, B. van; Bois, F.; Escher, Sylvia E.; Gardner, Iain
Abstract
2018In-situ characterization of e-cigarette aerosols by 90°-light scattering of polarized light
Dunkhorst, Wilhelm; Lipowicz, Peter; Li, Weiling; Hux, Casey; Wang, Qiang; Koch, Wolfgang
Journal Article
2018Innenraumluftqualität in Verkehrsflugzeugen
Rosenberger, Wolfgang; Schuchardt, Sven; Baumstark-Khan, C.; Hahn, A.
Book Article
2018International consensus statement on allergy and rhinology: Allergic rhinitis
Wise, Sarah K.; Lin, Sandra Y.; Toskala, Elina; Orlandi, Richard R.; Akdis, Cezmi A.; Alt, Jeremiah A.; Azar, Antoine; Baroody, Fuad M.; Bachert, Claus; Canonica, G. Walter; Chacko, Thomas; Cingi, Cemal; Ciprandi, Giorgio; Corey, Jacquelynne; Cox, Linda S.; Creticos, Peter Socrates; Custovic, Adnan; Damask, Cecelia; DeConde, Adam; DelGaudio, John M.; Ebert, Charles S.; Eloy, Jean Anderson; Flanagan, Carrie E.; Fokkens, Wytske J.; Franzese, Christine; Gosepath, Jan; Halderman, Ashleigh; Hamilton, Robert G.; Hoffman, Hans Jürgen; Hohlfeld, Jens M.; Houser, Steven M.; Hwang, Peter H.; Incorvaia, Cristoforo; Jarvis, Deborah; Khalid, Ayesha N.; Kilpeläinen, Maritta; Kingdom, Todd T.; Krouse, Helene; Larenas-Linnemann, Desiree; Laury, Adrienne M.; Lee, Stella E.; Levy, Joshua M.; Luong, Amber U.; Marple, Bradley F.; McCoul, Edward D.; McMains, K. Christopher; Melén, Erik; Mims, James W.; Moscato, Gianna; Mullol, Joaquim; Nelson, Harold S.; Patadia, Monica; Pawankar, Ruby; Pfaar, Oliver; Platt, Michael P.;
Journal Article
2018Investigation into pulmonary absorption using a combination of the ex vivo model of isolated perfused rat lungs and a simple PK model
Schwarz, Katharina; Koch, Wolfgang; Walter, Dorothee
Abstract
2018Investigations on classification and mechanisms of MWCNT-Induced carcinogenicity
Schwotzer, Daniela; Schaudien, Dirk; Rittinghausen, Susanne; Meyer-Plath, Asmus; Eckert, V.; Leonhardt, A.; Creutzenberg, Otto H.; Gebel, Thomas
Abstract
2018Isolated aggregates of lymphoid cells in the inner bronchial wall in asthma patients
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Journal Article
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Journal Article
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Journal Article
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Brandsma, Joost; Goss, Victoria M.; Yang, Xian; Bakke, Per S.; Caruso, Massimo; Chanez, Pascal; Dahlén, Sven-Erik; Fowler, Stephen J.; Horváth, Ildikó; Krug, Norbert; Montuschi, Paolo; Sanak, Marek; Sandström, Thomas; Shaw, Dominick E.; Chung, Kian Fan; Singer, Florian; Fleming, Louise J.; Sousa, Ana R.; Pandis, Ioannis; Bansal, Aruna T.; Sterk, Peter J.; Djukanović, Ratko; Postle, Anthony D.
Journal Article
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Journal Article
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Conference Paper
2018Low-energy electron-beam treatment as alternative for on-site sterilization of highly functionalized medical products - a feasibility study
Gotzmann, G.; Portillo, J.; Wronski, S.; Kohl, Y; Gorjup, E.; Schuck, H.; Rögner, F.-H.; Müller, M.; Chaberny, I.F.; Schönfelder, J.; Wetzel, C.
Journal Article
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Book Article
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Feldmann, Jörg; Blümlein, Katharina; Krupp, Eva Maria; Müller, Martin; Wood, Barry A.
Book Article
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Journal Article
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Journal Article
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Journal Article
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Journal Article
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Journal Article
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Journal Article
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Journal Article
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Journal Article
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Journal Article
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Journal Article
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Journal Article
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Abstract
2018Physiologisch basierte toxikokinetische (PBTK) Modellierung zur Aufnahme von Chemikalien/Aerosolen über die Lunge
Winkler, Daniel Sandro
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Master Thesis
2018Platox in vitro and in vivo investigations (28-day inhalation) to generate valid toxicity data for risk assessment of carbon-based nanoplatelets
Creutzenberg, Otto H.; Ziemann, Christina; Oliveira, H.; Farcal, L.; Burla, S.
Abstract
2018The PLATOX project: Combining in vitro and in vivo investigations to generate valid toxicity data for risk assessment of graphene nanoplatelets
Creutzenberg, Otto H.; Ziemann, Christina; Schaudien, Dirk; Oliveira, Helena; Farcal, Lucian
Abstract
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Escher, Sylvia E.; Tolosa Pardo, L.; Maclennan, R.; Stöber, R.; Limonciel, A.; Fisher, C.; Brotzmann, K.; Vugt-Lussenburg, B.M. van; Vrijenhoek, N.G.; Gräpel, R.
Abstract
2018Prenatal treatment with rosiglitazone attenuates vascular remodeling and pulmonary monocyte influx in experimental congenital diaphragmatic hernia
Gosemann, Jan-Hendrik; Friedmacher, Florian; Hofmann, Alejandro; Zimmer, Julia; Kuebler, Joachim F.; Rittinghausen, Susanne; Suttkus, Anne; Lacher, Martin; Alvarez, Luis; Corcionivoschi, Nicolae; Puri, Prem
Journal Article
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Baric, Valentin; Grossmann, Henrike Katharina; Koch, Wolfgang; Mädler, Lutz
Journal Article
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Hesse, Susanne; Hahn, Stefan; Lamb, Judith; Basinas, Ioannis; Apsley, Andrew; Tongeren, Martie van; Urbanus, J.; Pizzella, G.; Banton, M.; Dudzina, T.; Tibaldi, R.; Geudens, B.; Jones, R.; Ketelslegers, H.; Trantallidi, M.
Report
2018RIFM fragrance ingredient safety assessment 2,4-dimethylbenzyl acetate, CAS Registry Number 62346-96-7
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2018RIFM fragrance ingredient safety assessment 2-Benzylheptanol, CAS Registry Number 92368-90-6
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2018RIFM fragrance ingredient safety assessment 2-methyl-trans-2-butenoic acid, CAS Registry Number 80-59-1
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2018RIFM fragrance ingredient safety assessment 5,8-Methano-2H-1-benzopyran-2-one, 6- ethylideneoctahydro-, CAS Registry Number 69486-14-2
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2018RIFM fragrance ingredient safety assessment β-Patchoulene, CAS Registry Number 514-51-2
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Dekant, W.; Fryer, A.D.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Wahler, J.
Journal Article
2018RIFM fragrance ingredient safety assessment benzyl 2,2-dimethylpropanoate, CAS Registry Number 2094-69-1
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2018RIFM fragrance ingredient safety assessment cyclohexanecarboxylic acid, CAS Registry Number 98-89-5
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2018RIFM fragrance ingredient safety assessment diethyl succinate, CAS Registry Number 123-25-1
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2018RIFM fragrance ingredient safety assessment dihydro-β-terpinyl acetate, CAS Registry Number 26252-11-9
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2018RIFM fragrance ingredient safety assessment Dimethyl succinate, CAS Registry Number 106-65-0
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2018RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT p-Methylanisole, CAS Registry Number 104-93-8
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; BruzE, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; DekanT, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; la Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2018RIFM fragrance ingredient safety assessment phenethyl isovalerate, CAS Registry Number 140-26-1
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2018RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT phenylethyl 2-methylbutyrate, CAS Registry Number 24817-51-4
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; Cava, S.L.A.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2018RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT, [2-Isopropoxyethyl]benzene, CAS Registry Number 68039-47-4
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, (Z)-4-hepten-1-ol, CAS Registry Number 6191-71-5
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2018RIFM fragrance ingredient safety assessment, (Z)-Octadec-9-enol, CAS Registry Number 143-28-2
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, 1,1-diethoxyisooctane, CAS Registry Number 69178-43-4
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2018RIFM fragrance ingredient safety assessment, 1,2,3,4,5,6,7,8,9,10-decahydro-5,9-methanobenzocycloocten-11-one, CAS Registry Number 22690-27-3
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, 1,3-Benzodioxole-5-propanol, α-methyl-, 5-acetate, CAS Registry Number 68844-96-2
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, 1,3-dimethylbut-3-enyl isobutyrate, CAS Registry Number 80118-06-5
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, 1-(3,3-dimethylbicyclo[2.2.1]hept-2-yl)ethane-1-one, CAS Registry Number 42370-07-0
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT, 1-Methyl-2-(1-methylpropyl)cyclohexyl acetate, CAS Registry Number 72183-75-6
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT, 1-Oxaspiro[4.5]decan-2-one, 8-(1-methylethyl)-, trans-, CAS Registry Number 4625-90-5
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, 1-oxaspiro[4.5]decan-2-one, 8-methyl-, CAS Registry Number 94201-19-1
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT, 2,6-Dimethylocta-2,4,6-triene, CAS Registry Number 673-84-7
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, 2-ethylhexyl acetate, CAS Registry Number 103-09-3
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, 2-Hexylcyclopentanone, CAS Registry Number 13074-65-2
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT, 2-Methyl-2-hepten-6-ol, CAS Registry Number 1569-60-4
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, 2-methylhexanoic acid, CAS Registry Number 4536-23-6
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, 2-methylundecanal dimethyl acetal, CAS Registry Number 68141-17-3
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2018RIFM fragrance ingredient safety assessment, 2-Methylvaleric acid, CAS Registry Number 97-61-0
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM Fragrance ingredient safety assessment, 2-nonen-1-ol, CAS registry number 22104-79-6
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, 2H-Inden-2-one, 1,3-dihydro-, CAS Registry Number 615-13-4
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, 3-(cis-3-hexenyloxy)propanenitrile, CAS Registry Number 142653-61-0
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, 3-methyl-1-pentanol, CAS Registry Number 589-35-5
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2018RIFM fragrance ingredient safety assessment, 3-methyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)pent-4-en-2-ol, CAS Registry Number 67801-20-1
Api, A.M.; Belsito, D.; Bhatia, S.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; Kromidas, L.; La Cava, S.; Lalko, J.F.; Lapczynski, A.; Liebler, D.C.; Miyachi, Y.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Politano, V.T.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.; Wall, B.; Wilcox, D.K.
Journal Article
2018RIFM fragrance ingredient safety assessment, 3-Methylbutanal diethyl acetal, CAS Registry Number 3842-03-3
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2018RIFM fragrance ingredient safety assessment, 3-tert-butylcyclohexyl acetate, CAS Registry Number 31846-06-7
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2018RIFM fragrance ingredient safety assessment, 3a,4,5,6,7,7a-hexahydro-4,7-methano-1H-inden-5-yl pivalate, CAS Registry Number 68039-45-2
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, 4′-methylacetophenone, CAS Registry Number 122-00-9
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT, 4,8-Dimethyl-3-7-nonadien-2-ol, CAS Registry Number 67845-50-5
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, 4-Hexen-1-ol, (4Z)-, CAS Registry Number 928-91-6
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; Cava, S.L.A.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2018RIFM fragrance ingredient safety assessment, 4-pentenoic acid, 2-acetyl-4-methyl-, ethyl ester, CAS Registry Number 20962-70-3
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, 5,9-undecadien-2-ol,6,10-dimethyl-,acetate, CAS Registry Number 91482-37-0
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, acetal, CAS Registry Number 105-57-7
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, acetophenone, CAS Registry Number 98-86-2
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, Amylcyclohexyl acetate (mixed isomers), CAS Registry Number 67874-72-0
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2018RIFM fragrance ingredient safety assessment, β-caryophyllene alcohol, CAS Registry Number 472-97-9
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, benzyl formate, CAS Registry Number 104-57-4
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2018RIFM fragrance ingredient safety assessment, benzyl isoamyl ether, CAS Registry Number 122-73-6
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, benzyl methyl ether, CAS Registry Number 538-86-3
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, bis(hydroxymethyl)tricyclo[5.2.1.02,6]decane, CAS Registry Number 26160-83-8
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT, butanoic acid, 3a,4,5,6,7,7a-hexahydro-4,7-methano-1H-indenyl ester, CAS Registry Number 113889-23-9
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT, Butyl phenylacetate, CAS Registry Number 122-43-0
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, butyrophenone, cas Registry Number 495-40-9
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, cis-3-octenyl propionate, CAS Registry Number 94134-03-9
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, cis-5-octen-1-ol CAS Registry Number 64275-73-6
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2018RIFM fragrance ingredient safety assessment, dihydroterpinyl acetate, CAS registry number 58985-18-5
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, dodecanal dimethyl acetal, CAS Registry Number 14620-52-1
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2018RIFM fragrance ingredient safety assessment, dodecanenitrile, CAS Registry Number 2437-25-4
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2018RIFM fragrance ingredient safety assessment, endo-1,2,3,3-tetramethylbicyclo[2.2.1]heptan-2-ol, CAS Registry Number 28462-85-3
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, ethyl phenylacetate, CAS Registry Number 101-97-3
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, Fenchone, CAS Registry Number 1195-79-5
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, geranic acid, CAS Registry Number 459-80-3
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, heptanal dimethyl acetal, CAS Registry Number 10032-05-0
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2018RIFM fragrance ingredient safety assessment, hexahydro-3H-benzofuran-2-one, CAS Registry Number 6051-03-2
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, Hexyl acetate, CAS Registry Number 142-92-7
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, hexyl benzoate, CAS Registry Number 6789-88-4
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, hexyl formate, CAS Registry Number 629-33-4
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, isobutyl benzoate, CAS registry number 120-50-3
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, isophorol, CAS Registry Number 470-99-5
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, l-menthyl lactate, CAS Registry Number 59259-38-0
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2018RIFM fragrance ingredient safety assessment, methyl benzoate, CAS Registry Number 93-58-3
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM Fragrance ingredient safety assessment, methylheptenol, CAS Registry Number 1335-09-7
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, nonane, 1,1-diethoxy-, CAS Registry Number 54815-13-3
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, nonyl acetate, CAS Registry Number 143-13-5
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, octanal dimethyl acetal, CAS Registry Number 10022-28-3
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; Cava, S.L.A.; Lapczynski, A.; Liebler, D.C.; O'brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2018RIFM fragrance ingredient safety assessment, octyl butyrate, CAS Registry Number 110-39-4
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, p-(2,2-dimethoxyethoxy)toluene, CAS Registry Number 6324-78-3
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, p-tert-butylacetophenone, CAS Registry Number 943-27-1
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, pentanedioic acid, 1,5-dimethyl ester, CAS Registry Number 1119-40-0
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2018RIFM fragrance ingredient safety assessment, phenethyl tiglate, CAS Registry Number 55719-85-2
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2018RIFM fragrance ingredient safety assessment, terpinyl acetate (isomer mixture), CAS Registry number 8007-35-0
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT, Terpinyl butyrate, CAS Registry Number 2153-28-8
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, terpinyl formate, CAS Registry Number 2153-26-6
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, terpinyl propionate, CAS Registry Number 80-27-3
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, trans-2-Hexenol, CAS Registry Number 928-95-0
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, tricyclodecanyl acetate, CAS Registry Number 64001-15-6
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
2018RIFM fragrance ingredient safety assessment, Valencene, CAS Registry Number 4630-07-3
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.
Journal Article
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Conference Paper
2017An Adverse Outcome Pathway for Sensitization of the Respiratory Tract by Low-Molecular-Weight Chemicals
Sullivan, K.M.; Enoch, S.J.; Ezendam, J.; Sewald, K.; Roggen, E.L.; Cochrane, S.
Journal Article
2017Adverse outcome pathways: Opportunities, limitations and open questions
Leist, M.; Ghallab, A.; Graepel, R.; Marchan, R.; Hassan, R.; Bennekou, S.H.; Limonciel, A.; Vinken, M.; Schildknecht, S.; Waldmann, T.; Danen, E.; Ravenzwaay, B. van; Kamp, H.; Gardner, I.; Godoy, P.; Bois, F.Y.; Braeuning, A.; Reif, R.; Oesch, F.; Drasdo, D.; Höhme, S.; Schwarz, M.; Hartung, T.; Braunbeck, T.; Beltman, J.; Vrieling, H.; Sanz, F.; Forsby, A.; Gadaleta, D.; Fisher, C.; Kelm, J.; Fluri, D.; Ecker, G.; Zdrazil, B.; Terron, A.; Jennings, P.; Burg, B. van der; Dooley, S.; Meijer, A.H.; Willighagen, E.; Martens, M.; Evelo, C.; Mombelli, E.; Taboureau, O.; Mantovani, A.; Hardy, B.; Koch, B.; Escher, S.; Thriel, C. van; Cadenas, C.; Kroese, D.; Water, B. van de; Hengstler, J.G.
Journal Article
2017Allergen exposure chambers: harmonizing current concepts and projecting the needs for the future - an EAACI Position Paper
Pfaar, O.; Calderon, M.A.; Andrews, C.P.; Angjeli, E.; Bergmann, K.C.; Bonlokke, J.H.; Blay, F. de; Devillier, P.; Ellis, A.K.; Wijk, R.G. van; Hohlfeld, J.M.; Horak, F.; Jacobs, R.L.; Jacobsen, L.; Jutel, M.; Kaul, S.; Larche, M.; Larenas-Linnemann, D.; Mosges, R.; Nolte, H.; Patel, P.; Peoples, L.; Rabin, R.L.; Rather, C.; Salapatek, A.M.; Sigsgaard, T.; Thaarup, S.; Yang, J.; Zieglmayer, P.; Zuberbier, T.; Demoly, P.
Journal Article
2017Anti-viral and inflammatory host response to rhinovirus is induced in vital ex vivo human lung tissue and reduced by anti-viral treatments
Obernolte, H.; Braubach, P.; Jonigk, D.; Kruger, M.; Warnecke, G.; Pfennig, O.; Fieguth, H.-G.; Braun, A.; Sewald, K.; Wronski, S.
Abstract
2017Antibiotic mixture effects on growth of the leaf-shredding stream detritivore Gammarus fossarum
Bundschuh, Mirco; Hahn, Torsten; Gessner, Mark O.; Schulz, Ralf
Journal Article
2017Aseptische Abfüllung biopharmazeutischer Prüfarzneimittel
Baydoun, Luma; Ziehr, Holger
Journal Article
2017Assessment of long-term cultivated human precision-cut lung slices as an ex vivo system for evaluation of chronic cytotoxicity and functionality
Neuhaus, V.; Schaudien, D.; Golovina, T.; Temann, U.-A.; Thompson, C.; Lippmann, T.; Bersch, C.; Pfennig, O.; Jonigk, D.; Braubach, P.; Fieguth, H.-G.; Warnecke, G.; Yusibov, V.; Sewald, K.; Braun, A.
Journal Article
2017Between-User Reliability of Tier 1 Exposure Assessment Tools Used Under REACH
Lamb, J.; Galea, K.S.; Miller, B.G.; Hesse, S.; Tongeren, M. van
Journal Article
2017Biokinetics of nanomaterials. The role of biopersistence
Laux, Peter; Riebeling, Christian; Booth, Andy M.; Brain, Joseph D.; Brunner, Josephine; Cerrillo, Cristina; Creutzenberg, Otto H.; Estrela-Lopis, Irina; Gebel, Thomas; Johanson, Gunnar; Jungnickel, Harald; Kock, Heiko; Tentschert, Jutta; Tlili, Ahmed; Schäffer, Andreas; Sips, Adriënne J.A.M.; Yokel, Robert A.; Luch, Andreas
Journal Article
2017Biological effects of carbon black nanoparticles are changed by surface coating with polycyclic aromatic hydrocarbons
Lindner, Karina; Ströbele, Michael; Schlick, Sandra; Webering, Sina; Jenckel, André; Kopf, Johannes; Danov, Olga; Sewald, Katherina; Buj, Christian; Creutzenberg, Otto; Tillmann, Thomas; Pohlmann, Gerhard; Ernst, Heinrich; Ziemann, Christina; Hüttmann, Gereon; Heine, Holger; Bockhorn, Henning; Hansen, Tanja; König, Peter
Journal Article
2017Blood eosinophils predict therapeutic effects of a GATA3-specific DNAzyme in asthma patients
Krug, N.; Hohlfeld, J.M.; Buhl, R.; Renz, J.; Garn, H.; Renz, H.
Journal Article
2017Catch and release: Rare cell analysis from a functionalised medical wire
Chen, Shukun; El-Heliebi, Amin; Tauber, Gerlinde; Langsenlehner, Tanja; Pötscher, Michaela; Kashofer, Karl; Czyz, Zbigniew T.; Polzer, Bernhard; Riethdorf, Sabine; Kuske, Andra; Leitinger, Gerd; Pantel, Klaus; Kroneis, Thomas; Sedlmayr, Peter
Journal Article
2017Class I histone deacetylases regulate p53/NF-kappaB crosstalk in cancer cells
Schäfer, Claudia; Göder, Anja; Beyer, Mandy; Kiweler, Nicole; Mahendrarajah, Nisintha; Rauch, Anke; Nikolova, Teodora; Stojanovic, Natasa; Wieczorek, Martin; Reich, Thomas R.; Tomicic, Maja T.; Linnebacher, Michael; Sonnemann, Jürgen; Dietrich, Sascha; Sellmer, Andreas; Mahboobi, Siavosh; Heinzel, Thorsten; Schneider, Günter; Krämer, Oliver H.
Journal Article
2017Coagulation factor XII regulates inflammatory responses in human lungs
Hess, R.; Wujak, L.; Hesse, C.; Sewald, K.; Jonigk, D.; Warnecke, G.; Fieguth, H.-G.; Maat, S. de; Maas, C.; Bonella, F.; Preissner, K.T.; Weiss, B.; Schaefer, L.; Kuebler, W.M.; Markart, P.; Wygrecka, M.
Journal Article
2017Comparison Of Bleomycin Models Of Pulmonary Fibrosis In Rats And Mice
Walter, D.; Schaudien, D.; Sewald, K.; Braun, A.; Hoymann, H.G.
Abstract
2017Curated human hyperbilirubinemia data and the respective OATP1B1 and 1B3 inhibition predictions
Kotsampasakou, Eleni; Escher, Sylvia E.; Ecker, Gerhard F.
Journal Article
2017Differential lower airway dendritic cell patterns may reveal distinct endotypes of RSV bronchiolitis
Kerrin, A.; Fitch, P.; Errington, C.; Kerr, D.; Waxman, L.; Riding, K.; McCormack, J.; Mehendele, F.; McSorley, H.; MacKenzie, K.; Wronski, S.; Braun, A.; Levin, R.; Theilen, U.; Schwarze, J.
Journal Article
2017Disseminated tumour cells with highly aberrant genomes are linked to poor prognosis in operable oesophageal adenocarcinoma
Schumacher, S.; Bartenhagen, C.; Hoffmann, M.; Will, D.; Fischer, J.C.; Baldus, S.E.; Vay, C.; Fluegen, G.; Dizdar, L.; Vallböhmer, D.; Klein, C.A.; Knoefel, W.T.; Stoecklein, N.H.; Möhlendick, B.
Journal Article
2017Dose-response relationship of a new Timothy grass pollen allergoid in comparison with a 6-grass pollen allergoid
Pfaar, O.; Hohlfeld, J.M.; Al-Kadah, B.; Hauswald, B.; Homey, B.; Hunzelmann, N.; Schliemann, S.; Velling, P.; Worm, M.; Klimek, L.
Journal Article
2017Effect of a nano-silver coating on the quality of fresh turkey meat during storage after modified atmosphere or vacuum packaging
Deus, D.; Kehrenberg, C.; Schaudien, Dirk; Klein, G.; Krischek, Carsten
Journal Article
2017Effects from a 90-day inhalation toxicity study with cerium oxide and barium sulfate nanoparticles in rats
Schwotzer, D.; Ernst, H.; Schaudien, D.; Kock, H.; Pohlmann, G.; Dasenbrock, C.; Creutzenberg, O.
Journal Article
2017Erfahrungen und unterstützende Hinweise zur Anwendung von Nintedanib bei Patienten mit idiopathischer Lungenfibrose
Behr, Jürgen; Günther, Andreas; Kreuter, Michael; Koschel, Dirk; Prasse, Antje; Pfeifer, Michael; Costabel, Ulrich
Journal Article
2017Establishment of Neurospora crassa as a host for heterologous protein production using a human antibody fragment as a model product
Havlik, D.; Brandt, U.; Bohle, K.; Fleissner, A.
Journal Article
2017A European Respiratory Society technical standard: exhaled biomarkers in lung disease
Horvath, I.; Barnes, P.J.; Loukides, S.; Sterk, P.J.; Hogman, M.; Olin, A.C.; Amann, A.; Antus, B.; Baraldi, E.; Bikov, A.; Boots, A.W.; Bos, L.D.; Brinkman, P.; Bucca, C.; Carpagnano, G.E.; Corradi, M.; Cristescu, S.; Jongste, J.C. de; Dinh-Xuan, A.T.; Dompeling, E.; Fens, N.; Fowler, S.; Hohlfeld, J.M.; Holz, O.; Jobsis, Q.; Kant, K.V. van de; Knobel, H.H.; Kostikas, K.; Lehtimaki, L.; Lundberg, J.; Montuschi, P.; Muylem, A. van; Pennazza, G.; Reinhold, P.; Ricciardolo, F.L.M.; Rosias, P.; Santonico, M.; Schee, M.P. van der; Schooten, F.J. van; Spanevello, A.; Tonia, T.; Vink, T.J.
Journal Article
2017Evaluation of a human in vitro hepatocyte-NPC co-culture model for the prediction of idiosyncratic drug-induced liver injury: A pilot study
Granitzny, Anne; Knebel, Jan; Müller, Meike; Braun, Armin; Steinberg, Pablo; Dasenbrock, Clemens; Hansen, Tanja
Journal Article
2017Evaluation of inflammatory and immune responses in long-term cultured human precision-cut lung slices
Temann, A.; Golovina, T.; Neuhaus, V.; Thompson, C.; Chichester, J.A.; Braun, A.; Yusibov, V.
Journal Article, Conference Paper
2017Evaluation of Tier One Exposure Assessment Models (ETEAM): Project Overview and Methods
Tischer, M.; Lamb, J.; Hesse, S.; Tongeren, M. van
Journal Article
2017Ex-Vivo Infection Of Fresh Human Lung Tissue With Pseudomonas AerugINOSa
Boge, L.; Muller, M.; Jonigk, D.; Braubach, P.; Fieguth, H.G.; Warnecke, G.; Kruger, M.; Braun, A.; Sewald, K.; Wronski, S.
Abstract
2017Fraunhofer-Institut für Toxikologie und Experimentelle Medizin. Leistungen und Ergebnisse. Jahresbericht 2016/2017
: Nastevska, Cathrin (Red.); Schlemminger, Karin (Übers.)
Annual Report
2017FXII promotes proteolytic processing of the LRP1 ectodomain
Wujak, L.; Hesse, C.; Sewald, K.; Jonigk, D.; Braubach, P.; Warnecke, G.; Fieguth, H.-G.; Braun, A.; Lochnit, G.; Markart, P.; Schaefer, L.; Wygrecka, M.
Journal Article
2017GC-MS and GC-MS/MS measurement of ibuprofen in 10-μL aliquots of human plasma and mice serum using alpha-methylo-H-2(3)]ibuprofen after ethyl acetate extraction and pentafluorobenzyl bromide derivatization
Tsikas, Dimitrios; Kayacelebi, Arslan Arinc; Hanff, Erik; Mitschke, Anja; Beckmann, Bibiana; Tillmann, Hanns-Christian; Gutzki, Frank-Mathias; Müller, Meike; Bernasconi, Corrado
Journal Article
2017Health related quality of life in patients with idiopathic pulmonary fibrosis in clinical practice: insights-IPF registry
Kreuter, M.; Swigris, J.; Pittrow, D.; Geier, S.; Klotsche, J.; Prasse, A.; Wirtz, H.; Koschel, D.; Andreas, S.; Claussen, M.; Grohe, C.; Wilkens, H.; Hagmeyer, L.; Skowasch, D.; Meyer, J.F.; Kirschner, J.; Glaser, S.; Herth, F.J.F.; Welte, T.; Neurohr, C.; Schwaiblmair, M.; Held, M.; Bahmer, T.; Frankenberger, M.; Behr, J.
Journal Article
2017HER2 FISH results in breast cancers with increased CEN17 signals using alternative chromosome 17 probes - reclassifying cases in the equivocal category
Holzschuh, M.-A.; Czyz, Z.; Hauke, S.; Inwald, E.C.; Polzer, B.; Brockhoff, G.
Journal Article
2017High pressure processing assisted enzymatic hydrolysis - An innovative approach for the reduction of soy immunoreactivity
Meinlschmidt, Pia; Brode, Viktoria; Sevenich, R.; Ueberham, E.; Schweiggert-Weisz, U.; Lehmann, J.; Rauh, C.; Knorr, D.; Eisner, P.
Journal Article
2017A high-throughput method for the quantitative determination of free amino acids in saccharomyces cerevisiae by hydrophilic interaction chromatography-tandem mass spectrometry
Mülleder, M.; Bluemlein, K.; Ralser, M.
Journal Article
2017Human effector memory T helper cells engage with mouse macrophages and cause Graft-versus-Host-like pathology in skin of humanized mice used in a nonclinical immunization study
Sundarasetty, Balasai; Volk, Valery; Theobald, Sebastian J.; Rittinghausen, Susanne; Schaudien, Dirk; Neuhaus, Vanessa; Figueiredo, Constanca; Schneider, Andreas; Gerasch, Laura; Mucci, Adele; Moritz, Thomas; Kaisenberg, Constantin von; Spineli, Loukia M.; Sewald, Katherina; Braun, Armin; Weigt, Henning; Ganser, Arnold; Stripecke, Renata
Journal Article
2017In silico toxicology: An overview of toxicity databases, prediction methodologies, and expert review
Bower, D.; Cross, K.P.; Escher, Sylvia E.; Myatt, Glenn J.; Quigley, D.P.
Book Article
2017In vitro/ex vivo liver models for the prediction of idiosyncratic drug-induced liver injury
Granitzny, A.
Dissertation
2017Influence of lung CT changes in chronic obstructive pulmonary disease (COPD) on the human lung microbiome
Engel, M.; Endesfelder, D.; Schloter-Hai, B.; Kublik, S.; Granitsiotis, M.S.; Boschetto, P.; Stendardo, M.; Barta, I.; Dome, B.; Deleuze, J.F.; Boland, A.; Müller-Quernheim, J.; Prasse, A.; Welte, T.; Hohlfeld, J.; Subramanian, D.; Parr, D.; Gut, I.G.; Greulich, T.; Koczulla, A.R.; Nowinski, A.; Gorecka, D.; Singh, D.; Gupta, S.; Brightling, CE.; Hoffmann, H.; Frankenberger, M.; Hofer, TP.; Burggraf, D.; Heiss-Neumann, M.; Ziegler-Heitbrock, L.; Schloter, M.; Castell, W. zu
Journal Article
2017Influence of modified atmosphere and vacuum packaging with and without nanosilver-coated films on different quality parameters of pork
Kernberger-Fischer, I.; Kehrenberg, C.; Klein, G.; Schaudien, D.; Krischek, C.
Journal Article
2017Influences of Experimental Air Pollution on Human Sympathetic Nerve Traffic and Norepinephrine Metabolism: A Double Blind, Randomized, Twofold Crossover Study
Tank, J.; Heusser, K.; Holz, O.; May, M.; Brinkmann, J.; Diedrich, A.; Framke, T.; Koch, A.; Grosshennig, A.; Sweep, F.C.G.J.; Koch, W.; Krug, N.; Jordan, J.; Hohlfeld, J.
Abstract
2017Interactions Of Cancer Cell Line Mda-Mb-231 With Their Native Tumor Microenvironment And Anti-Cancer Effects Of Bevacizumab And Cisplatin On Cancer Cell Invaded Human Living Lung Tissue
Konzok, S.; Dehmel, S.; Braubach, P.; Kruger, M.; Jonigk, D.; Warnecke, G.; Pfennig, O.; Fieguth, H.G.; Braun, A.; Sewald, K.
Abstract
2017Intubation-free in vivo imaging of the tracheal mucosa using two-photon microscopy
Veres, Tibor Z.; Kopcsányi, Támas; Tirri, Marko; Braun, Armin; Miyasaka, Masayuki; Germain, Ronald N.; Jalkanen, Sirpa; Salmi, Marko
Journal Article
2017The isolated perfused lung (IPL) model for toxicity and efficacy testing and absorption studies of inhalable substances
Schwarz, K.; Fischer, M.; Dasenbrock, C.; Koch, W.; Walter, D.
Abstract
2017Legacy data sharing to improve drug safety assessment
Sanz, F.; Pognan, F.; Steger-Hartmann, T.; Díaz, C.; Cases, M.; Pastor, M.; Marc, P.; Wichard, J.; Briggs, K.; Watson, D.K.; Kleinöder, T.; Yang, C.; Amberg, A.; Beaumont, M.; Brookes, A.J.; Brunak, S.; Cronin, M.T.D.; Ecker, G.F.; Escher, S.; Greene, N.; Guzmán, A.; Hersey, A.; Jacques, P.; Lammens, L.; Mestres, J.; Muster, W.; Northeved, H.; Pinches, M.; Saiz, J.; Sajot, N.; Valencia, A.; Lei,, J. van der; Vermeulen, N.P.E.; Vock, E.; Wolber, G.; Zamora, I.
Journal Article
2017Linking organic anion transporting polypeptide 1B1 and 1B3 (OATP1B1 and OATP1B3) interaction profiles to hepatotoxicity - The hyperbilirubinemia use case
Kotsampasakou, Eleni; Escher, Sylvia E.; Ecker, Gerhard F.
Journal Article
2017Maintenance of high quality rat precision cut liver slices during culture to study hepatotoxic responses: Acetaminophen as a model compound
Granitzny, Anne; Knebel, Jan; Schaudien, Dirk; Braun, Armin; Steinberg, Pablo; Dasenbrock, Clemens; Hansen, Tanja
Journal Article
2017Molecular mechanism of early metastatic breast cancer dissemination
Hosseini, H.
Dissertation
2017The NAD+ precursor nicotinic acid improves genomic integrity in human peripheral blood mononuclear cells after X-irradiation
Weidele, Kathrin; Beneke, Sascha; Bürkle, Alexander
Journal Article
2017Non-human primate orthologues of TMPRSS2 cleave and activate the influenza virus hemagglutinin
Zmora, Pawel; Molau-Blazejewska, Paulina; Bertram, Stephanie; Walendy-Gnirß, Kerstin; Nehlmeier, Inga; Hartleib, Anika; Moldenhauer, Anna-Sophie; Konzok, Sebastian; Dehmel, Susann; Sewald, Katherina; Brinkmann, Constantin; Curths, Christoph; Knauf, Sascha; Gruber, Jens; Mätz-Rensing, Kerstin; Dahlmann, Franziska; Braun, Armin; Pöhlmann, Stefan
Journal Article
2017Organosilane-based coating of quartz species from the traditional ceramics industry: Evidence of hazard reduction using in vitro and in vivo tests
Ziemann, Christina; Escrig, Alberto; Bonvicini, Giuliana; Ibañez, Maria Jesus; Monfort, Eliseo; Salomoni, Arturo; Creutzenberg, Otto H.
Journal Article
2017Partikel‐ und Fasertoxikologie
Halter, Roman; Mangelsdorf, Inge
Book Article
2017Plasminogen activator inhibitor-1 is elevated in patients with COPD independent of metabolic and cardiovascular function
Waschki, Benjamin; Watz, Henrik; Holz, Olaf; Magnussen, Helgo; Olejnicka, Beata; Welte, Tobias; Rabe, Klaus F.; Janciauskiene, Sabina
Journal Article
2017The potential acute and chronic toxicity of cyfluthrin on the soil model organism, Eisenia fetida
Li, L.; Yang, D.; Song, Y.; Shi, Y.; Huang, B.; Bitsch, A.; Yan, J.
Journal Article
2017Pre-triggered dry and liquid aerosol release inside the patient interface of preterm neonates
Wiegandt, F.C.; Koch, E.; Iwatschenko, P.; Dietzel, A.; Pohlmann, G.
Abstract
2017Pseudomonas aeruginosa induziert eine angeborene Immunantwort in frischem Lungengewebe ex vivo
Kraemer, Nadine
: Braun, Armin (1. Prüfer); Häußler, Susanne (2. Prüfer); Wronski, Sabine (Betr.); Müller, Laura (Betr.)
Master Thesis
2017Read-across of 90-day rat oral repeated-dose toxicity: A case study for selected β-olefinic alcohols
Przybylak, Katarzyna R.; Schultz, Terry W.; Richarz, Andrea-N.; Mellor, Claire L.; Escher, Sylvia E.; Cronin, M.T.D.
Journal Article
2017Read-across of 90-day rat oral repeated-dose toxicity: A case study for selected n-alkanols
Schultz, Terry W.; Przybylak, Katarzyna R.; Richarz, Andrea-Nicole; Mellor, Claire L.; Escher, Sylvia E.; Bradbury, Steven P.; Cronin, Mark T. D.
Journal Article
2017Reduced microRNA-503 expression augments lung fibroblast VEGF production in chronic obstructive pulmonary disease
Ikari, J.; Nelson, A.J.; Obaid, J.; Giron-Martinez, A.; Ikari, K.; Makino, F.; Iwasawa, S.; Gunji, Y.; Farid, M.; Wang, X.; Basma, H.; Demeo, D.; Feghali-Bostwick, C.; Holz, O.; Rabe, K.; Liu, X.; Rennard, S.I.
Journal Article
2017Reply to Comment on 'Canine scent detection for the diagnosis of lung cancer in a screening-like situation'
Hackner, K.; Errhalt, P.; Doll, T.
Journal Article
2017Respirationstrakt
Schulz, F.
Book Article
2017RFIM fragrance ingredient safety assessment, acetaldehyde ethyl phenylethyl acetal, CAS Registry Number 2556-10-7
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment 2-heptylcyclopentanone, CAS Registry Number 137-03-1
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment 4-(Isopropyl)cyclohexyl propionate, CAS Registry Number 63449-95-6
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, .α.-methylcyclohexylmethyl acetate, CAS Registry Number 13487-27-9
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, 1-cyclohexylethyl butyrate, CAS Registry Number 63449-88-7
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, Jochen; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A. D.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, 1-methyl-3-methoxy-4-isopropylbenzene, CAS Registry Number 1076-56-8
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM Fragrance Ingredient Safety Assessment, 2,2,4-trimethyl-4-phenyl-butane-nitrile CAS Registry Number 75490-39-0
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, 2,2,5-trimethyl-5-pentylcyclopentanone, CAS Registry Number 65443-14-3
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, 2-isopropyl-4-methylanisole, CAS Registry Number 31574-44-4
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, 2-methyl-4(2,2,3-trimethyl-3-cyclopentenyl)butanol, CAS Registry Number 72089-08-8
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, 2-pentylcyclopentan-1-one, CAS Registry Number 4819-67-4
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, 3,12-Tridecadienenitrile CAS Registry Number 134769-33-8
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, 3,6-nonadien-1-ol, CAS registry number 76649-25-7
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, 3,7-dimethyl-1-octanol, CAS Registry Number 106-21-8
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, 3,7-dimethyl-1-octanyl acetate, CAS Registry Number 20780-49-8
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, 3,7-dimethyl-2,6-nonadienenitrile, CAS Registry Number 61792-11-8
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, 3-hexen-1-ol (isomer unspecified), CAS Registry Number 544-12-7
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, 3-methyl-2-pentylcyclopentan-1-one, CAS Registry Number 13074-63-0
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, 3-methylbutyl 2-methylpropanoate, CAS Registry Number 2050-01-3
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, 3-methylbutyl valerate, CAS Registry Number 2050-09-1
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, 4-(3,4-methylenedioxyphenyl)-2-butanone, CAS Registry Number 55418-52-5
Api, A.M.; Belsito, D.; Bhatia, S.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; Kromidas, L.; La Cava, S.; Lalko, J.F.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Politano, V.T.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.; Wall, B.; Wilcox, D.K.
Journal Article
2017RIFM fragrance ingredient safety assessment, 4-Carvomenthenol, CAS Registry Number 562-74-3
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, 4-isopropyl-2-methoxy-1-methylbenzene, CAS Registry Number 6379-73-3
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, 5-Acetyl-3-isopropyl-1,1,2,6-tetramethylindane, CAS Registry Number 68140-48-7
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT, 6-acetyl-1,1,2,4,4,7-hexamethyltetraline, CAS Registry Number 21145-77-7
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Dekant, W.; Fryer, A.D.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, α-methylbenzyl alcohol, CAS registry number 98-85-1
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, α-Propylphenethyl alcohol, CAS Registry Number 705-73-7
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, acetaldehyde, diphenethyl acetal, CAS Registry Number 122-71-4
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, acetic acid, C7-9-branched alkyl esters, C8-rich, CAS Registry Number 108419-32-5
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, acetic acid, C8-10-branched alkyl esters, C9-rich, CAS Registry Number 108419-33-6
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, Alcohols, C11-14-iso-, C13-rich, CAS Registry Number 68526-86-3
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, alcohols, C8-10-iso-, C9-rich, CAS Registry Number 68526-84-1
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, β-Guaiene, CAS Registry Number 88-84-6
Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Dekant, W.; Fryer, A.D.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, β-methylphenethyl alcohol, CAS Registry Number 1123-85-9
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, benzenepropanenitrile, 4-ethyl-.α.,.α.-dimethyl, CAS Registry Number 134123-93-6
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, benzenepropanol, a,ß-dimethyl-, CAS Registry Number 56836-93-2
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, benzoic acid, 2-[(1-oxopropyl)amino]-, methyl ester, CAS Registry Number 25628-84-6
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, butyl anthranilate, CAS Registry Number 7756-96-9
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, cis-3-octen-1-ol, CAS Registry Number 20125-84-2
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, cis-6-nonen-1-ol, CAS Registry Number 35854-86-5
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, Citronellyl nitrile, CAS Registry Number 51566-62-2
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, cuminyl nitrile, CAS Registry Number 13816-33-6
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, cyclohexanecarboxylic acid, 1,4-dimethyl-, methyl ester, trans- CAS Registry Number 23250-42-2
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM Fragrance Ingredient Safety Assessment, d-Cyclocitronellene acetate, CAS Registry Number 25225-10-9
Api, A.M.; Belsito, D.; Bhatia, S.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Kromidas, L.; La Cava, S.; Lalko, J.; Lapczynski, A.; Liebler, D.C.; Miyachi, Y.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Politano, V.T.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.; Wall, B.; Wilcox, D.K.
Journal Article
2017RIFM fragrance ingredient safety assessment, decanal dimethyl acetal, CAS Registry Number 7779-41-1
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, dihydro-α-terpineol, CAS Registry Number 498-81-7
Api, A.M.; Belsito, D.; Bhatia, S.; Botelho, D.; Browne, D.; Bruze, M.; Burton, A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; Kromidas, L.; La Cava, S.; Lalko, J.F.; Lapczynski, A.; Liebler, D.C.; Miyachi, Y.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Politano, V.T.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.; Wall, B.; Wilcox, D.K.
Journal Article
2017RIFM fragrance ingredient safety assessment, dihydro-β-ionol, cas registry number 3293-47-8
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, elemol, CAS Registry Number 639-99-6
Api, A.M.; Belsito, D.; Bhatia, S.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; Kromidas, L.; La Cava, S.; Lalko, J.F.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Politano, V.T.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.; Wall, B.; Wilcox, D.K.
Journal Article
2017RIFM fragrance ingredient safety assessment, Ethyl 2,3,6-trimethylcyclohexyl carbonate, CAS Registry Number 93981-50-1
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, ethyl 2-tert-butylcyclohexyl carbonate, CAS Registry Number 67801-64-3
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, ethylene dodecanedioate, CAS registry number 54982-83-1
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, α-Isobutylphenethyl alcohol, CAS Registry Number 7779-78-4
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, isoamyl acetate, CAS Registry Number 123-92-2
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, isoamyl alcohol CAS Registry Number 123-51-3
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, Isoamyl butyrate, CAS Registry Number 106-27-4
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, isoamyl formate, CAS Registry Number 110-45-2
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, isoamyl hexanoate, CAS Registry Number 2198-61-0
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, Isoamyl octanoate, CAS Registry Number 2035-99-6
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, isoamyl propionate, CAS Registry Number 105-68-0
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, isobutyl N-methylanthranilate, CAS Registry Number 65505-24-0
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, isodecyl alcohol, CAS registry number 25339-17-7
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, Isolongifolene ketone, CAS registry number 23787-90-8
Api, A.M.; Belsito, D.; Bhatia, S.; Botelho, D.; Brown, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Fryer, A.D.; Kromidas, L.; Lalko, J.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Politano, V.T.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Thakkar, Y.; Wahler, J.; Wall, B.; Wilcox, D.K.
Journal Article
2017RIFM fragrance ingredient safety assessment, isononyl propionate, CAS Registry Number 65155-45-5
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, isotridecyl acetate, CAS registry number 69103-23-7
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, l-Cyclocitronellene formate, CAS Registry Number 25225-08-5
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, menthyl acetate (isomer unspecified), CAS Registry Number 16409-45-3
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, menthyl isovalerate CAS Registry Number 16409-46-4
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, methyl anthranilate, CAS Registry Number 134-20-3
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, Methyl hexyl oxo cyclopentanone carboxylate, CAS Registry Number 37172-53-5
Api, A.M.; Belsito, D.; Bhatia, S.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; Kromidas, L.; La Cava, S.; Lalko, J.F.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Politano, V.T.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.; Wall, B.; Wilcox, D.K.
Journal Article
2017RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT, Methyl jasmonate, CAS Registry Number 1211-29-6
Api, A.M.; Belsito, D.; Bhatia, S.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; Kromidas, L.; La Cava, S.; Lalko, J.F.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Politano, V.T.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.; Wall, B.; Wilcox, D.K.
Journal Article
2017RIFM fragrance ingredient safety assessment, methyl N-acetylanthranilate, CAS Registry Number 2719-08-6
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, Methylcyclooctyl carbonate, CAS Registry Number 61699-38-5
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, oxacyclohexadecane-2,13-dione, CAS Registry Number 38223-29-9
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, p-(2,2-dimethoxyethyl)toluene, CAS Registry Number 42866-91-1
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, p-methoxybenzonitrile, CAS Registry Number 874-90-8
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, phenylacetaldehyde diethyl acetal, CAS Registry Number 6314-97-2
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, propyl phenethyl acetal, CAS Registry Number 7493-57-4
Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.
Journal Article
2017RIFM fragrance ingredient safety assessment, terpineol, CAS Registry Number 8000-41-7
Api, A.M.; Belsito, D.; Bhatia, S.; Botelho, D.; Browne, D.; Bruze, M.; Burton, A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; Kromidas, L.; La Cava, S.; Lalko, J.F.; Lapczynski, A.; Liebler, D.C.; Miyachi, Y.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Politano, V.T.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.; Wall, B.; Wilcox, D.K.
Journal Article
2017RIFM fragrance ingredient safety assessment, tetrahydro-4-methyl-2-(2-methylpropen-1-yl)pyran, CAS Registry Number 16409-43-1
Api, A.M.; Belsito, D.; Bhatia, S.; Botelho, D.; Browne, D.; Bruze, M.; Burton, A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; Kromidas, L.; Cava, S. la; Lalko, J.F.; Lapczynski, A.; Liebler, D.C.; Miyachi, Y.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Politano, V.T.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.; Wall, B.; Wilcox, D.K.
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Abstract
2016Acute toxicity and environmental risks of five veterinary pharmaceuticals for aquatic macroinvertebrates
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Abstract
2016Angiopoietin-like protein 4 and cardiovascular function in COPD
Waschki, Benjamin; Kirsten, Anne-Marie; Holz, Olaf; Meyer, T.; Lichtinghagen, R.; Rabe, K.F.; Magnussen, Helgo; Welte, T.; Watz, H.; Janciauskiene, S.
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Behrsing, H.; Raabe, H.; Manuppello, J.; Bombick, B.; Curren, R.; Sullivan, K.; Sethi, S.; Phipps, R.; Tesfaigzi, Y.; Yan, S.; D'Ruiz, C.; Tarran, R.; Constant, S.; Phillips, G.; Gaca, M.; Hayden, P.; Cao, X.; Mathis, C.; Hoeng, J.; Braun, A.; Hill, E.
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Metcalf, J.P.; Booth, J.L.; Duggan, E.S.; Patel, V.I.; Langer, M.; Braun, A.; Coggeshall, K.M.
Abstract
2016Bacillus anthracis spore movement does not require a carrier cell and is not affected by lethal toxin in human lung models
Booth, J.L.; Duggan, E.S.; Patel, V.I.; Langer, M.; Wu, W.; Braun, A.; Coggeshall, K.M.; Metcalf, J.P.
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Buschmann, J.
Abstract
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Abstract
2016Comparative dosimetry for children and rodents exposed to extremely low-frequency magnetic fields
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Holz, O.; Allers, M.; Gaida, A.; Schuchardt, S.; Hohlfeld, J.M.; Zimmermann, S.
Abstract
2016Compounds with As-S bonds: Analytical and biogeochemical reasons why these species have been elusive in biota and environment
Feldmann, Jörg; Raab, Andrea; Hansen, Helle R.; Blümlein, Katharina; Wallschläger, Dirk
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Gong, Yijian; Capstick, Myles; Tillmann, Thomas; Dasenbrock, Clemens; Samaras, Theodoros; Kuster, Niels
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Ritter, D.; Knebel, J.; Wronski, S.; Montes, A.; Niehof, M.
Abstract
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Prasse, A.
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Konzok, S.; Braubach, P.; Peter, D.; Jonigk, D.; Fieguth, H.-G.; Braun, A.; Sewald, K.
Abstract
2016Double-blind randomized multicenter clinical trial to evaluate the specific and non-specific effects of AIT with a grass and a birch pollen allergoid
Wagenmann, M.; Hohlfeld, J.; Tribanek, M.; Homolla, V.; Karjalainen, M.; Häfner, D.
Abstract
2016A dual center study to compare breath volatile organic compounds from smokers and non-smokers with and without COPD
Gaida, Arne; Holz, Olaf; Nell, Christoph; Schuchardt, Sven; Lavae-Mokhtari, Bianca; Kruse, Lena; Boas, Ursula; Langejuergen, Jens; Allers, Maria; Zimmermann, Stefan
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Hosseini, Hedayatollah; Obradović, Milan M.S.; Hoffmann, Martin; Harper, Kathryn L.; Sosa, Maria Soledad; Werner-Klein, Melanie; Nanduri, Lahiri Kanth; Werno, Christian; Ehrl, Carolin; Maneck, Matthias; Patwary, Nina; Haunschild, Gundula; Gužvić, Miodrag; Reimelt, Christian; Grauvogl, Michael; Eichner, Norbert; Weber, Florian; Hartkopf, Andreas D.; Taran, Florin-Andrei; Brucker, Sara Y.; Fehm, Tanja; Rack, Brigitte; Buchholz, Stefan; Spang, Rainer; Meister, Gunter; Aguirre-Ghiso, Julio A.; Klein, Christoph A.
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Abstract
2016Emphysema- and airway-dominant COPD phenotypes defined by standardised quantitative computed tomography
Subramanian, Deepak R.; Gupta, Sumit; Burggraf, Dorothe; Silberberg, Suzan J. vom; Heimbeck, Irene; Heiss-Neumann, Marion S.; Haeussinger, Karl; Newby, Chris; Hargadon, Beverley; Raj, Vimal; Singh, Dave; Kolsum, Umme; Hofer, Thomas P.; Al-Shair, Khaled; Luetzen, Niklas; Prasse, Antje; Müller-Quernheim, Joachim; Benea, Giorgio; Leprotti, Stefano; Boschetto, Piera; Gorecka, Dorota; Nowinski, Adam; Oniszh, Karina; Castell, Wolfgang zu; Hagen, Michael; Barta, Imre; Döme, Balazs; Strausz, Janos; Greulich, Timm; Vogelmeier, Claus; Koczulla, Andreas R.; Gut, Ivo; Hohlfeld, Jens; Welte, Tobias; Lavae-Mokhtari, Mahyar; Ziegler-Heitbrock, Loems; Brightling, Christopher; Parr, David G.
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2016Endokrin wirksame Umweltchemikalien in Lebensmitteln
Schäfers, C.; Licht, O.; Bitsch, A.
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2016Endokrin wirksame Umweltchemikalien in Lebensmitteln
Schäfers, C.; Licht, O.; Bitsch, A.
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2016Endokrin wirksame Umweltchemikalien in Lebensmitteln
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Borlak, J.; Buettner, S.M.R.
Abstract
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Brodbeck, Carsten; Ritter, Detlef; Knebel, Jan; Wolf, Klaus
Patent
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Tran, Doan Duy Hai; Koch, Alexandra; Saran, Shashank; Armbrecht, Marcel; Ewald, Florian; Koch, Martina; Wahlicht, Tom; Wirth, Dagmar; Braun, Armin; Nashan, Bjorn; Gaestel, Matthias; Tamura, Teruko
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Annual Report
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Hoymann, H.G.; Schaudien, D.; Hansen, T.; Niehof, M.; Braun, A.
Abstract
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Ernst, Heinrich; Ma-Hock, Lan; Keller, J.; Groeters, Sibylle; Ravenzwaay, Bennard van; Gebel, Thomas; Schaudien, Dirk; Rittinghausen, Susanne; Landsiedel, Robert
Abstract
2016In vitro and in vivo investigations to obtain validated toxicity data of graphene nanoplatelets
Farcal, L.; Ziemann, C.; Oliveira, H.; Burla, S.; Creutzenberg, O.
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Gundlach, Enken; Hoffmann, Michael Marcus; Prasse, Antje; Heinzelmann, Sonja; Ness, Thomas
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Brinkman, P.; Wagener, A.H.; Hekking, P.-P.; Bansal, A.T.; Wang, Y.; Weda, H.; Knobel, H.H.; Vink, T.J.; Rattray, NJ.; D'Amico, A.; Pennazza, G.; Santonico, M.; Bakke, P.S.; Caruso, M.; Chung, K.F.; Corfield, J.; Dahlen, S.E.; Djukanovic, R.; Geiser, T.; Horvath, I.; Krug, N.; Musial, J.; Shaw, D.E.; Pandis, I.; Sandstrom, T.; Sousa, A.R.; Montuschi, P.; Fowler, S.J.; Sterk, P.J.
Abstract
2016Marmoset monkeys as a model for human allergic asthma
Curths, C.; Jimenez-Delgado, S.; Wichmann, J.; Kap, Y.; Kaup, F.-J.; Braun, A.; Sewald, K.; Knauf, S.; Dahlmann, F.
Abstract
2016Massive clonal selection and transiently contributing clones during expansion of mesenchymal stem cell cultures revealed by lentiviral RGB-barcode technology
Selich, Anton; Daudert, Jannik; Hass, Ralf; Philipp, Friederike; Kaisenberg, Constantin von; Paul, Gabi; Cornils, Kerstin; Fehse, Boris; Rittinghausen, Susanne; Schambach, Axel; Rothe, Michael
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Gilfanov, Artur K.; Koch, Wolfgang; Zaripov, Shamil K.
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Harper, Kathryn L.; Sosa, Maria Soledad; Entenberg, David; Hosseini, Hedayatollah; Cheung, Julie F.; Nobre, Rita; Avivar-Valderas, Alvaro; Nagi, Chandandaneep; Girnius, Nomeda; Davis, Roger J.; Farias, Eduardo F.; Condeelis, John; Klein, Christoph A.; Aguirre-Ghiso, Julio A.
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Abstract
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Creutzenberg, Otto H.; Hansen, Tanja; Schuchardt, Sven; Tillmann, Thomas; Knebel, Jan
Abstract
2016Mice produced by mitotic reprogramming of sperm injected into haploid parthenogenotes
Suzuki, Toru; Asami, Maki; Hoffmann, Martin; Lu, Xin; Guzvic, Miodrag; Klein, Christoph A.; Perry, Anthony C.F.
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Sundarasetty, B.S.; Schneider, A.; Sewald, K.; Rittinghausen, S.; Braun, A.; Figueiredo, C.; Ganser, A.; Stripecke, R.
Abstract
2016Nonproliferative and proliferative lesions of the rat and mouse skeletal tissues (bones, joints, and teeth)
Fossey, Stacey; Vahle, John; Long, Philip; Schelling, Scott; Ernst, Heinrich; Boyce, Rogely Waite; Jolette, Jacquelin; Bolon, Brad; Bendele, Alison; Rinke, Matthias; Healy, Laura; High, Wanda; Roth, Daniel Robert; Boyle, Michael; Leininger, Joel
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Wichmann, J.; Jimenez-Delgado, S.; Curths, C.; Schmitt, A.; Dunker, S.; Jonigk, D.; Braubach, P.; Kaup, F.J.; Braun, A.; Dahlmann, F.; Eggel, A.; Sewald, K.; Knauf, S.
Abstract
2016Numerical study of nanoparticle formation in a free turbulent jet
Gilfanov, A.K.; Koch, W.; Zaripov, S.K.; Rybdylova, O.D.
Conference Paper
2016Prevalence of ragweed sensitization at a clinical trial unit in northern Germany
Badorrek, P.; Krug, N.; Hohlfeld, J.M.
Abstract
2016Prevalidation of the ex-vivo model PCLS for prediction of respiratory toxicity
Hess, A.; Wang-Lauenstein, Lan; Braun, Armin; Kolle, S.N.; Landsiedel, Robert; Liebsch, M.; Ma-Hock, Lan; Pirow, R.; Schneider, X.; Steinfath, M.; Vogel, S.; Martin, C.; Sewald, Katherina
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Holz, O.; Gaida, A.; Nell, C.; Allers, M.; Schuchardt, S.; Zimmermann, S.; Koczulla, R.; Hohlfeld, J.M.
Abstract
2016Recommendations from the INHAND Apoptosis/Necrosis Working Group
Elmore, Susan A.; Dixon, Darlene; Hailey, James R.; Harada, Takanori; Herbert, Ronald A.; Maronpot, Robert R.; Nolte, Thomas; Rehg, Jerold E.; Rittinghausen, Susanne; Rosol, Thomas J.; Satoh, Hiroshi; Vidal, Justin D.; Willard-Mack, Cynthia L.; Creasy, Dianne M.
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Api, A.M.; Belsito, D.; Bhatia, S.; Bruze, M.; Burton, G.A.; Buschmann, Jochen; Calow, P.; Dagli, M.L.; Dekant, W.; Fryer, A.D.; Kromidas, L.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Penning, T.M.; Politano, V.T.; Ritacco, G.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Wall, B.; Wilcox, D.K.
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Lüer, Katrin; Biller, Heike; Casper, Anja; Windt, Horst; Müller, Meike; Badorrek, Philipp; Haefner, Dietrich; Framke, Theodor; Koch, A.; Ziehr, Holger; Krug, Norbert; Koch, Wolfgang; Hohlfeld, Jens M.
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Nendza, Monika; Wenzel, Andrea; Müller, Martin; Lewin, Geertje; Simetska, Nelly; Stock, Frauke; Arning, Jürgen
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Wilson, Susan J.; Ward, Jonathan A.; Sousa, Ana R.; Corfield, Julie; Bansal, Aruna T.; Meulder, Bertrand de; Lefaudeux, Diane; Auffray, Charles; Loza, Matthew J.; Baribaud, Frédéric; Fitch, Neil; Sterk, Peter J.; Chung, Kian Fan; Gibeon, David; Sun, Kai; Guo, Yi-Ke; Adcock, Ian M.; Djukanovic, Ratko; Dahlén, Barbro; Chanez, Pascal; Shaw, Dominick E.; Krug, Norbert; Hohlfeld, Jens; Sandström, Thomas; Howarth, Peter H.
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Shrestha, Prasit; Junker, Thomas; Fenner, Kathrin; Hahn, Stefan; Honti, Mark; Bakkour, Rani; Diaz, Cecilia; Hennecke, Dieter
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Heinrichs, Martin; Ernst, Heinrich
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Le, Duc Dung; Funck, Ulrike; Wronski, Sabine; Heck, Sebastian; Tschernig, Thomas; Bischoff, Markus; Sester, Martina; Herr, Christian; Bals, Robert; Welte, Tobias; Braun, Armin; Dinh, Quoc Thai
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Escher, S.; Turek, C.; Campos, S.; Edwards, J.; Ferret, P.; Höfer, N.; Kosemund, K.; Schnabel, J.; Ravenzwaay, B. van; Hollnagel, H.M.
Abstract
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Koschmann, J.; Sewald, K.; Escher, S.E.
Journal Article
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Calverley, Peter M.A.; Könen-Bergmann, Michael; Richard, Frank; Bell, Susan; Hohlfeld, Jens M.
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Gužvić, M.; Klein, C.A.
Journal Article
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Schwotzer, Daniela; Niehof, Monika; Hansen, Tanja; Schuchardt, Sven; Tillmann, Thomas; Ernst, Heinrich; Creutzenberg, Otto H.
Abstract
2016Toxicity of cerium dioxide nanoparticles - effects from a 90-day inhalation study
Schwotzer, D.; Niehof, M.; Hansen, T.; Tillmann, T.; Ernst, H.; Creutzenberg, O.
Abstract
2016Transient Receptor Potential (TRP) ion channels activation in vital human precision-cut lung slices lead to bronchoconstriction and is neuropeptide substance P-dependent
Delgado, S.M.J.; Obernolte, H.; Hobbie, S.; Schindler, S.; Jonigk, D.; Warnecke, G.; Braubach, P.; Bersch, C.; Pfennig, O.; Fieguth, H.G.; Sewald, K.; Braun, A.
Abstract
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Creutzenberg, Otto H.; Kock, Heiko; Schaudien, Dirk
Journal Article
2016Use of computational fluid dynamics for optimization of cell-based in vitro methods in inhalation research
Brodbeck, C.; Wolf, K.; Ritter, D.; Knebel, J.
Abstract
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Loza, M.J.; Djukanovic, R.; Chung, K.F.; Horowitz, D.; Ma, K.; Branigan, P.; Barnathan, E.S.; Susulic, V.S.; Silkoff, P.E.; Sterk, P.J.; Baribaud, F.; Badorrek, P.; Faulenbach, C.; Braun, A.; Hohlfeld, J.; Krug, N.; et. al.
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Journal Article
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Bludau, E.
Dissertation
2015Acute inhalation toxicity of volatile organic compounds - application of an improved cell-based in vitro procedure
Ritter, Detlef; Krakor, E.; Knebel, Jan
Abstract
2015Acute toxicity testing of inhalable/gaseous compounds by cell-based methods in vitro - application to volatile organic compounds
Ritter, Detlef; Knebel, Jan
Abstract
2015Allergen-induced asthmatic responses modified by a GATA3-specific DNAzyme
Krug, Norbert; Hohlfeld, Jens Michael; Kirsten, Anne-Marie; Kornmann, Oliver; Beeh, Kai-Michael; Kappeler, Dominik; Korn, Stephanie; Ignatenko, Stanislav; Timmer, Wolfgang; Rogon, Cordelia; Zeitvogel, Jana; Zhang, Nan; Bille, Joachim; Homburg, Ursula; Turowska, Agnieszka; Bachert, Claus; Werfel, Thomas; Buhl, Roland; Renz, Jonas; Garn, Holger; Renz, Harald
Journal Article
2015Assessing the breathing capability of patients through inhalers
Pohlmann, G.; Hohlfeld, J.; Pankalla, J.
Conference Paper, Journal Article
2015Assessment of mechanisms driving non-linear dose-response relationships in genotoxicity testing
Guerard, M.; Baum, M.; Bitsch, Annette; Eisenbrand, G.; Elhajouji, A.; Epe, B.; Habermeyer, M.; Kaina, B.; Martus, H.J.; Pfuhler, S.; Schmitz, C.; Sutter, A.; Thomas, A.D.; Ziemann, Christina; Froetschl, R.
Journal Article
2015Beryllium concentrations at european workplaces: Comparison of 'total' and inhalable particulate measurements
Kock, Heiko; Civic, Terence; Koch, Wolfgang
Journal Article
2015Beryllium concentrations at European workplaces: Comparison of ‘total’ and inhalable particulate measurements
Koch, W.; Kock, H.; Civic, T.
Conference Paper, Journal Article
2015Biologische Wirkungen synthetisch hergestellter Multiwall-Carbon-Nanotubes am Tiermodell und in der Zellkultur
Hackbarth, Anja
: Steinberg, Pablo (Wiss. Betreuer); Dasenbrock, Clemens (Wiss. Betreuer); Steinberg, Pablo (1. Gutachter); Kietzmann, Manfred (2. Gutachter)
Dissertation
2015Cardiac safety of tiotropium in patients with COPD: A combined analysis of Holter-ECG data from four randomised clinical trials
Hohlfeld, Jens Michael; Furtwaengler, A.; Könen-Bergmann, M.; Wallenstein, G.; Walter, B.; Bateman, E.D.
Journal Article
2015Cellular uptake of different nano and bulk metal oxide particles by cells derived from epidermal, intestinal and leukocyte cell lines
Requardt, H.; Hansen, T.; Eisenbarth, E.; Hampel, S.; Dasenbrock, C.
Conference Paper, Journal Article
2015Characterization of exhaled particles from the human lungs in airway obstruction
Schwarz, Katharina; Biller, Heike; Windt, Horst; Koch, Wolfgang; Hohlfeld, Jens M.
Journal Article
2015The ChemScreen project to design a pragmatic alternative approach to predict reproductive toxicity of chemicals
Burg, Bart van der; Bay Wedebye, Eva; Dietrich, Daniel R.; Jaworska, Joanna; Mangelsdorf, Inge; Paune, Eduard; Schwarz, Michael; Piersma, Aldert H.
Journal Article
2015Childhood asthma is associated with mutations and gene expression differences of ORMDL genes that can interact
Toncheva, A.A.; Potaczek, D.P.; Schedel, M.; Gersting, S.W.; Michel, S.; Krajnov, N.; Gaertner, V.D.; Klingbeil, J.M.; Illig, T.; Franke, A.; Winkler, Carla; Hohlfeld, Jens M.; Vogelberg, C.; Berg, A. von; Bufe, A.; Heinzmann, A.; Laub, O.; Rietschel, E.; Simma, B.; Genuneit, J.; Muntau, A.C.; Kabesch, Michael
Journal Article
2015Cholinergic urethral brush cells are widespread throughout placental mammals
Deckmann, Klaus; Krasteva-Christ, Gabriela; Rafiq, Amir; Herden, Christine; Wichmann, Judy; Knauf, Sascha; Nassenstein, Christina; Grevelding, Christoph G.; Dorresteijn, Adriaan; Chubanov, Vladimir; Gudermann, Thomas; Bschleipfer, Thomas; Kummer, Wolfgang
Journal Article, Conference Paper
2015Cigarette smoke and cigarette smoke condensate exposure induces cytotoxicity and inflammation in precision-cut lung slices
Obernolte, Helena; Konzok, Sebastian; Ritter, Detlef; Knebel, Jan; Braubach, Peter; Jonigk, Danny; Fieguth, Hans-Gerd; Braun, Armin; Sewald, Katherina
Abstract
2015Cigarette smoke and cigarette smoke condensate induce cell injury and early biomarkers of inflammation in human and rodent Precision-Cut Lung Slices
Obernolte, Helena; Ritter, Detlef; Knebel, Jan W.; Braubach, Peter; Jonigk, Danny; Braun, Armin; Sewald, Katherina
Abstract
2015Cigarette smoke condensate and cigarette smoke induce cytotoxicity and inflammation in human and rodent Precision-Cut Lung Slices of different species
Obernolte, Helena; Konzok, Sebastian; Ritter, Detlef; Knebel, Jan W.; Braubach, Peter; Jonigk, Danny; Braun, Armin; Sewald, Katherina
Abstract
2015Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort
Shaw, Dominick E.; Sousa, Ana R.; Fowler, Stephen J.; Fleming, Louise J.; Roberts, Graham; Corfield, Julie; Pandis, Ioannis; Bansal, Aruna T.; Bel, Elisabeth H.; Auffray, Charles; Compton, Chris H.; Bisgaard, Hans; Bucchioni, Enrica; Caruso, Massimo; Chanez, Pascal; Dahlén, Barbro; Dahlén, Sven-Erik; Dyson, Kerry; Frey, Urs; Geiser, Thomas; Gerhardsson de Verdier, Maria; Gibeon, David; Guo, Yi-Ke; Hashimoto, Simone; Hedlin, Gunilla; Jeyasingham, Elizabeth; Hekking, Pieter-Paul W.; Higenbottam, Tim; Horváth, Ildikó; Knox, Alan J.; Krug, Norbert; Erpenbeck, Veit J.; Larsson, Lars X.; Lazarinis, Nikos; Matthews, John G.; Middelveld, Roelinde; Montuschi, Paolo; Musial, Jacek; Myles, David; Pahus, Laurie; Sandström, Thomas; Seibold, Wolfgang; Singer, Florian; Strandberg, Karin; Vestbo, Jorgen; Vissing, Nadja; Garnier, Christophe von; Adcock, Ian M.; Wagers, Scott; Rowe, Anthony; Howarth, Peter; Wagener, Ariane H.; Djukanovic, Ratko; Sterk, Peter J.; Chung, Kian Fan
Journal Article
2015Comparative data-mining across multiple toxicity databases harmonized by eTOX ontology to test hypotheses
Steger-Hartmann, T.; Pognan, F.; Sanz, F.; Briggs, K.; Escher, Sylvia; Kleinoeder, T.; Schwab, C.; Wichard, J.; Yang, C.
Abstract
2015Comparison of fibrotic and emphysematous alterations in the lungs of bleomycin-treated rats and hamsters
Hoymann, Heinz-G.; Schaudien, Dirk; Hansen, Tanja; Müller, Meike; Braun, Armin
Abstract
2015Comparison of two different application routes of nanosilver in rats - evidence for nanoparticles after silver ion treatment
Juling, S.; Lichtenstein, D.; Selve, S.; Oberemm, A.; Creutzenberg, Otto; Braeuning, A.; Lampen, A.
Abstract
2015Constant-load exercise decreases the serum concentration of myeloperoxidase in healthy smokers and smokers with COPD
Holz, Olaf; Roepcke, Stefan; Watz, Henrik; Tegtbur, Uwe; Lahu, Gezim; Hohlfeld, Jens Michael
Journal Article
2015Constructing an adverse outcome pathway for sensitization of the respiratory tract: Network thinking meets regulatory utility
Sullivan, K.; Cochrane, S.; Enoch, S.J.; Ezendam, J.; Patlewicz, G.; Roggen, E.L.; Sewald, Katherina
Abstract
2015Continuing harmonization of terminology and innovations for methodologies in developmental toxicology
Solecki, Roland; Rauch, Martina; Gall, Andrea; Buschmann, Jochen; Clark, Ruth; Fuchs, Antje; Kan, Haidong; Heinrich, Verena; Kellner, Rupert; Knudsen, Thomas B.; Li, Weihua; Makris, Susan L.; Ooshima, Yojiro; Paumgartten, Francisco; Piersma, Aldert H.; Schönfelder, Gilbert; Oelgeschläger, Michael; Schaefer, Christof; Shiota, Kohei; Ulbrich, Beate; Ding, Xuncheng; Chahoud, Ibrahim
Journal Article
2015Controlled exposure to grass pollen in an environmental challenge chamber induces a worsening of cutaneous symptoms in patients with atopic dermatitis
Heratizadeh, A.; Badorrek, P.; Kapp, A.; Niebuhr, M.; Roesner, L.M.; Karch, A.; Erpenbeck, V.J.; Loesche, C.; Jung, T.; Krug, N.; Hohlfeld, JM.; Werfel, T.
Abstract
2015DETECTIVE: Detection of Endpoints and Biomarkers for Repeated Dose Toxicity using in vitro Systems
Wink, S.; Water, B. van de; Reif, R.; Hammad, S.; Stöber, R.; Widera, A.; Hengstler, J.; Limonciel, A.; Jennings, P.; Escher, S.; Keun, H.; Kleinjans, J.; Kopp-Schneider, A.; Peterson, H.; Ringwald, A.; Rogiers, V.; Sachinidis, A.; Sickmann, A.; Vinken, M.; Spitkovsky, D.; Hescheler, J.
Book Article
2015Determination of markers that predict the individual response of perennial allergic subjects to house dust mite allergen in the Fraunhofer Environmental Challenge Chamber (ECC)
Hohlfeld, J.M.; Lüer, K.; Holz, O.; Häfner, D.; Koch, W.; Krug, N.
Abstract
2015Deterministic whole-genome amplification of single cells
Czyz, Zbigniew Tadeusz; Klein, Christoph A.
Book Article
2015Development of a co-culture model for the prediction of idiosyncratic drug-induced liver injury
Granitzny, Anne; Hansen, Tanja; Knebel, Jan W.; Dasenbrock, Clemens; Steinberg, Pablo
Abstract
2015Development of a human organotypic tumor invasion model of cancer cell line MDA-MB-231 in Precision-Cut Lung Slices (PCLS)
Konzok, Sebastian; Schindler, Susann; Jonigk, Danny; Braubach, Peter; Braun, Armin; Sewald, Katherina
Abstract
2015Development of Biomarker Based on a Read-Across Use Case on Valproic Acid Analogues
Escher, S.; Hengstler, J.
Book Article
2015Development of chemical categories by optimized clustering strategies
Bitsch, Annette; Batke, Monika; Gundert-Remy, U.; Gütlein, M.; Kramer, S.; Partosch, F.; Seeland, M.
Abstract
2015Development of hematological and immunological characteristics in neonatal rats
Sewald, Katherina; Müller, Meike; Buschmann, Jochen; Hansen, Tanja; Lewin, Geertje
Journal Article, Conference Paper
2015Disease progression and changes in physical activity in patients with chronic obstructive pulmonary disease
Waschki, Benjamin; Kirsten, Anne M.; Holz, Olaf; Müller, Kai-Christian; Schaper, Miriam; Sack, Anna-Lena; Meyer, Thorsten; Rabe, Klaus F.; Magnussen, Helgo; Watz, Henrik
Journal Article
2015Effects of different blood collection methods on indicators of welfare in mice
Tsai, P.P.; Schlichtig, A.; Ziegler, E.; Ernst, H.; Haberstroh, J.; Stelzer, H.D.; Hackbarth, H.
Journal Article
2015Efficacy and safety of a novel nasal steroid, S0597, in patients with seasonal allergic rhinitis
Badorrek, Philipp; Hohlfeld, Jens M.; Krug, Norbert; Joshi, Abhijeet; Raut, Atul
Journal Article
2015Efficacy and safety of inhaled calcium lactate PUR118 in the ozone challenge model - a clinical trial
Holz, Olaf; Biller, Heike; Müller, Meike; Kane, Katie; Rosano, Molly; Hanrahan, John; Hava, David L.; Hohlfeld, Jens M.
Journal Article
2015Eosinophils of the marmoset monkey (callithrix jacchus)
Gruber-Dujardin, E.; Curths, Christoph; Bleyer, Martina; Taubert, S.; Bauer, N.; Moritz, A.; Dahlmann, Franziska; Braun, Armin; Knauf, Sascha; Kaup, Franz Josef
Abstract
2015Erste Erfahrungen mit der interdisziplinären Durchführung einer gynäko-onkologischen frühen klinischen Prüfung im neuen Clinical Research Center Hannover
May, M.; Schindler, C.; Jordan, J.; Park-Simon, T.; Hillemanns, P.
Journal Article
2015Establishment of a saline lavage model in the isolated perfused rat lung
Walter, Dorothee; Fischer, Monika; Pohlmann, Gerhard; Kemkowski, J.; Muynck, C. de; Dasenbrock, Clemens
Abstract
2015Evaluating cardiac safety of tiotropium in patients with COPD: Combined analysis of Holter-ECG data from four trials
Hohlfeld, Jens M.; Furtwängler, Armin; Könen-Bergmann, Michael; Wallenstein, Gudrun; Walter, Blate; Bateman, Eric D.
Abstract
2015Evaluation of an alternative in vitro test battery for detecting reproductive toxicants in a grouping context
Kroese, Dinant E.; Bosgra, Sieto; Buist, Harrie E.; Lewin, Geertje; Linden, Sander C. van der; Man, Hai-yen; Piersma, Aldert H.; Rorije, Emiel; Schulpen, Sjors H. W.; Schwarz, Michael; Uibel, Frederik; Vugt-Lussenburg, Barbara M.A. van; Wolterbeek, Andre P.M.; Burg, Bart van der
Journal Article
2015Evaluation of the fate and pathological response in the lung and pleura of brake dust alone and in combination with added chrysotile compared to crocidolite asbestos following short-term inhalation exposure
Bernstein, David M.; Rogers, R.A.; Sepulveda, Rosalina; Kunzendorf, Peter; Bellmann, Bernd; Ernst, Heinrich; Creutzenberg, Otto H.; Phillips, James I.
Journal Article
2015Evaluation of the toxicity and data gaps of e-cigarette aerosol
May, Martin; Schwarz, Katharina; Koch, Wolfgang; Bitsch, Annette
Abstract
2015Exacerbation of atopic dermatitis on grass pollen exposure in an environmental challenge chamber
Werfel, T.; Heratizadeh, A.; Niebuhr, M.; Kapp, A.; Roesner, L.M.; Karch, A.; Erpenbeck, V.J.; Lösche, C.; Jung, T.; Krug, N.; Badorrek, P.; Hohlfeld, J.M.
Journal Article
2015Expositionsapparat
Ritter, Detlef; Knebel, Jan
Patent
2015Features of house-dust-mite induced asthma in marmoset monkeys
Curths, C.; Dahlmann, F.; Wichmann, J.; Becker, T.; Knauf, Y.; Kaup, F.-J.; Braun, A.; Knauf, S.
Abstract
2015Foam spray application of biocides: Investigation into aerosol inhalation exposure
Schwarz, Katharina; Holthenrich, Dagmar; Bissantz, Kathrin; Ehni, Markus; Bitsch, Annette
Journal Article
2015Fraunhofer-Institut für Toxikologie und Experimentelle Medizin. Leistungen und Ergebnisse. Jahresbericht 2014
 
Annual Report
2015The genetic heterogeneity of circulating tumor cells: a longitudinal study in breast cancer patients
Terracciano, M.; Buson, G.; Forcato, C.; Luca, F. de; Galardi, F.; Sero, V.; Pestrin, M.; Gabellini, S.; Koestler, C.; Czyz, Z.T.; Bregola, G.; Tononi, P.; Bolognesi, C.; Fontana, F.; Medoro, G.; Polzer, B.; Leo, A. di; Klein, C.A.; Manaresi, N.
Abstract
2015A high throughput screening system for predicting chemically-induced reproductive organ deformities
Burg, Bart van der; Pieterse, Bart; Buist, Harrie E.; Lewin, Geertje; Linden, Sander C. van der; Man, Hai-yen; Rorije, Emiel; Piersma, Aldert H.; Mangelsdorf, Inge; Wolterbeek, Andre P.M.; Kroese, Dinant E.; Vugt-Lussenburg, Barbara van
Journal Article
2015House-dust-mite induced features of asthma in marmoset monkeys
Curths, Christoph; Dahlmann, Franziska; Wichmann, Judy; Becker, Tamara; Knauf, Y.; Kaup, Franz-Josef; Braun, Armin; Knauf, Sascha
Abstract
2015IBS: An illustrator for the presentation and visualization of biological sequences
Liu, Wenzhong; Xie, Yubin; Ma, Jiyong; Luo, Xiaotong; Nie, Peng; Zuo, Zhixiang; Lahrmann, Urs; Zhao, Qi; Zheng, Yueyuan; Zhao, Yong; Xue, Yu; Ren, Jian
Journal Article
2015Identification and molecular characterization of different subpopulations of EpCAM-positive single disseminated cancer cells in prostate cancer
Polzer, B.; Guzvic, M.; Ganzer, R.; Weckermann, D.; Braun, B.; Appel, I.; Obradovic, M.; Huppert, V.; Klein, C.A.
Abstract
2015Die idiopathische Lungenfibrose
Prasse, Antje
Journal Article
2015In vitro toxicity testing of two multi-walled carbon nanotubes determined for the purpose of targeted drug delivery
Requardt, Hendrik; Hansen, Tanja; Eisenbarth, E.; Hampel, S.; Dasenbrock, Clemens
Abstract
2015In vivo evaluation of a magnesium-based degradable intramedullary nailing system in a sheep model
Rössig, Christina; Angrisani, Nina; Helmecke, Patrick; Besdo, Silke; Seitz, Jan-Marten; Welke, Bastian; Fedchenko, Nickolay; Kock, Heiko; Reifenrath, Janin
Journal Article
2015Induced cytotoxicity revealed species diversity of rat and human lung tissue by repeated chemical exposure
Danov, Olga; Escher, Sylvia E.; Schröder, Katrin; Vorgrimmler, David; Braubach, Peter; Jonigk, Danny; Warnecke, Gregor; Braun, Armin; Sewald, Katherina
Abstract
2015Influence of ELF-MF on the juvenile immune system of CD-1 mice
Müller, Meike; Ziemann, Christina; Tillmann, Thomas; Lewin, Geertje; Dasenbrock, Clemens
Abstract
2015Inhalation toxicity of carbon black depends on surface coating with polycyclic aromatic hydrocarbons
Hansen, Tanja; König, P.; Creutzenberg, Otto H.; Weinhold, K.; Schlick, S.; Tillmann, Thomas; Pohlmann, Gerhard; Kolling, Angelika; Ziemann, Christina; Kopf, Johannes; Ströbele, Michael; Bockhorn, H.; Danov, Olga; Sewald, Katherina; Müller, B.; Fehrenbach, Heinz
Abstract
2015Inter- and intrasubject variability of the inflammatory response to segmental endotoxin challenge in healthy volunteers
Holz, Olaf; Tan, Lisa; Schaumann, Frank; Müller, Meike; Scholl, Dorothea; Hidi, R.; McLeod, Alison; Krug, Norbert; Hohlfeld, Jens M.
Journal Article
2015International harmonization of nomenclature and diagnostic criteria (INHAND) progress to date and future plans
Keenan, C.M.; Baker, J.F.; Bradley, A.E.; Goodman, D.G.; Harada, T.; Herbert, R.; Kaufmann, W.; Kellner, R.; Mahler, B.; Meseck, E.; Nolte, T.; Rittinghausen, S.; Vahle, J.; Yoshizawa, K.
Journal Article
2015International harmonization of nomenclature and diagnostic criteria (INHAND): Progress to date and future plans
Keenan, C.M.; Baker, J.; Bradley, A.; Goodman, D.G.; Harada, T.; Herbert, R.; Kaufmann, W.; Kellner, Rupert; Mahler, B.; Meseck, E.; Nolte, T.; Rittinghausen, Susanne; Vahle, J.; Yoshizawa, K.
Journal Article
2015Kinetic and mechanistic study of the reaction of OH radicals with methylated benzenes: 1,4-dimethyl-, 1,3,5-trimethyl-, 1,2,4,5-, 1,2,3,5- and 1,2,3,4-tetramethyl-, pentamethyl-, and hexamethylbenzene
Alarcón, P.; Bohn, B.; Zetzsch, C.
Journal Article
2015Laser microdissection of FFPE tissue areas and subsequent whole genome amplification by Ampli1™
Czyz, Zbigniew Tadeusz; Stoecklein, Nikolas H.; Polzer, Bernhard
Book Article
2015Longitudinal genetic characterization of circulating tumor cells in metastatic breast cancer patients
Sero, V.; Luca, F. de; Doffini, A.; Galardi, F.; Pestrin, M.; Czyz, Z.T.; Buson, G.; Bregola, G.; Bolognesi, C.; Fontana, F.; Medoro, G.; Polzer, B.; Leo, A. di; Klein, C.A.; Manaresi, N.
Abstract
2015Method and kit for determining the genome integrity and/or the quality of a library of DNA-sequences otained by deterministic restriction site whole genome amplification
Klein, Christoph Andreas; Polzer, Bernhard Michael; Manaresi, Nicolo
Patent
2015Method for identification of low soluble, biopersistent dusts (GBS) at workplaces
Creutzenberg, Otto H.; Hansen, Tanja; Schuchardt, Sven; Tillmann, Thomas
Abstract
2015Mini-Sterilisator als Alternative
Wibbertmann, Axel
Journal Article
2015Molecular characterization of early disseminating cancer cells in non-small cell lung cancer
Yamaci, R.F.; Elsner, F.; Sziklavari, Z.; Potzger, T.; Hofmann, H.S.; Klein, C.
Abstract
2015Molecular mechanisms of early cancer cell dissemination in breast cancer
Hosseini, H.; Carolin, E.L.; Nanduri, L.K.; Werno, C.; Maneck, M.; Husemann, Y.; Klein, C.A.
Abstract
2015Monitoring method for inhalation exposure to gas oil vapour and aerosol
Urbanus, J.; Banton, M.; Carter, M.; Dudzina, T.; Geudens, B.; Jones, R.; Niemeck, G.; Pizzella, G.; Tibaldi, R.; Williams, S.; Rohde, A.; Ketelslegers, H.; Berger-Preiß, E.; Koch, W.; Schuchardt, S.
Report
2015Multi-analyte profiling of inflammatory mediators in COPD sputum - The effects of processing
Pedersen, Frauke; Holz, Olaf; Lauer, Gereon; Quintini, Gianluca; Kiwull-Schöne, Heidrun; Kirsten, Anne-Marie; Magnussen, Helgo; Rabe, Klaus F.; Goldmann, Torsten; Watz, Henrik
Journal Article
2015Neutrophil extracellular trap formation and extracellular DNA in sputum of stable COPD patients
Pedersen, Frauke; Marwitz, Sebastian; Holz, Olaf; Kirsten, Anne; Bahmer, Thomas; Waschki, Benjamin; Magnussen, Helgo; Rabe, Klaus F.; Goldmann, Torsten; Uddin, Mohib; Watz, Henrik
Journal Article
2015New investigations into the genotoxicity of cobalt compounds and their impact on overall assessment of genotoxic risk
Kirkland, David; Brock, Tom; Haddouk, Hasnaà; Hargeaves, Victoria; Lloyd, Melvyn; Mc Garry, Sarah; Proudlock, Raymond; Sarlang, Séverine; Sewald, Katherina; Sire, Guillaume; Sokolowski, Andrea; Ziemann, Cristina
Journal Article
2015Niedrig dosierte inhalative Endotoxin Provokation bei gesunden Probanden als Modell in der klinischen Atemwegsforschung
Janssen, Ole
: Hohlfeld, Jens M. (Betreuer); Braun, Armin (Referent); Dittrich, Anna-Maria (Korreferent)
Dissertation
2015Noninvasive quantification of airway inflammation following segmental allergen challenge with functional MR imaging: A proof of concept study
Renne, Julius; Hinrichs, Jan; Schönfeld, Christian; Gutberlet, Marcel; Winkler, Carla; Faulenbach, Cornelia; Jakob, Peter; Schaumann, Frank; Krug, Norbert; Wacker, Frank; Hohlfeld, Jens M.; Vogel-Claussen, Jens
Journal Article
2015A novel human organotypic tumor invasion model of cell line MDA-MB-231 in Precision-Cut Lung Slices (PCLS) to reduce animal experiments in preclinical oncology
Konzok, Sebastian; Schindler, Susann; Jonigk, Danny; Braubach, Peter; Braun, Armin; Sewald, Katherina
Abstract
2015A novel universal allergen challenge technique for efficacy testing of immunotherapy
Schwarz, K.; Lueer, K.; Biller, H.; Windt, H.; Badorrek, P.; Hafner, D.; Koch, A.; Krug, N.; Koch, W.; Hohlfeld, J.
Abstract
2015Optimization of curation of the dataset with data on repeated dose toxicity
Gundert-Remy, Ursula; Batke, Monika; Bitsch, Annette; Gütlein, Martin; Kramer, Stefan; Partosch, Falko; Seeland, Madeleine
Abstract
2015An overview of the InhalT-90 project - a 90-day inhalation toxicity study with CeO2 nanoparticles
Schwotzer, Daniela; Hansen, Tanja; Niehof, Monika; Creutzenberg, Otto
Abstract
2015Passively sensitized human organotypic tissue as asthma model to study mast cell-nerve interaction
Jiménez Delgado, S.M.; Schindler, S.; Sewald, K.; Armin, B.
Abstract
2015Pathogen reduction by ultraviolet C light effectively inactivates human white blood cells in platelet products
Pohler, Petra; Müller, Meike; Winkler, Carla; Schaudien, Dirk; Sewald, Katherina; Müller, Thomas H.; Seltsam, Axel
Journal Article
2015Peripheral sensory nerves stimulation lead to bronchoconstriction-augment in passive sensitized human precision-cut lung slices and Is histamine 1 receptor dependent
Jiménez Delgado, Sharon Melissa; Schindler, Susann; Sewald, Katherina; Braun, Armin
Abstract
2015Personalisierte Tumortherapie
Alberter, B.; Polzer, B.
Journal Article
2015Pharmacological MRI (phMRI) of the human central nervous system
Lanfermann, Heinrich; Schindler, Chris; Jordan, Jens; Krug, Norbert; Raab, Peter
Journal Article
2015Power requirement of pressurized metered-dose and dry powder inhalers (pMDIs AND DPIs)
Haidl, P.; Pohlmann, G.; Cloes, R.M.
Abstract
2015Precision-cut lung slices as an alternative model for repeated-dose inhalation toxicity
Neuhaus, Vanessa; Danov, Olga; Witte, J.; Romberg, Susanne; Escher, Syliva; Braun, Armin; Sewald, Katherina
Abstract
2015Principles of whole-genome amplification
Czyz, Zbigniew Tadeusz; Kirsch, Stefan; Polzer, Bernhard
Book Article
2015Refinement and enhancement of a database for dermal absorption data
Schmeinck, Sina; Bitsch, Annette; Genth, H.
Abstract
2015Risk assessment of inhalable read-across chemicals with different mode of action showed great differences in cytotoxicity in rat and human precision-cut lung slices
Danov, Olga; Schröder, Katrin; Braubach, Peter; Jonigk, D.; Warnecke, G.; Braun, Armin; Escher, Syliva; Sewald, Katherina
Abstract
2015Safety and tolerability of a novel inhaled GATA3 mRNA targeting DNAzyme in patients with TH2-driven asthma
Homburg, Ursula; Renz, Harald; Timmer, Wolfgang; Hohlfeld, Jens M.; Seitz, Friedeborg; Lüer, Katrin; Mayer, Alexandra; Wacker, Anja; Schmidt, Oliver; Kuhlmann, Jens; Turowska, Agnieszka; Roller, Julia; Kutz, Klaus; Schlüter, Gerhard; Krug, Norbert; Garn, Holger
Journal Article
2015A saline lavage model in the isolated perfused rat lung
Walter, Dorothee; Fischer, Monika; Steinberg, Pablo; Dasenbrock, Clemens
Abstract
2015Selection of additives for reducing the toxicity of quartz in ceramic compositions
Escrig, A.; Ibanez, M.J.; Monfort, E.; Bonvicini, G.; Salomoni, A.; Creutzenberg, O.; Ziemann, C.
Journal Article
2015Serious magic-nano-like lung oedemas caused by a liquid stain protection product: Using two new tests as a combined screening tool for aerosol products
Hahn, A.; Fischer, M.; Walter, D.; Dasenbrock, C.; Koch, W.; Begemann, K.; Greiner, M.
Abstract
2015The serotonin receptor 5-HT7R regulates the morphology and migratory properties of dendritic cells
Holst, Katrin; Guseva, Daria; Schindler, Susann; Sixt, Michael; Braun, Armin; Chopra, Himpriya; Pabst, Oliver; Ponimaskin, Evgeni
Journal Article
2015The SILICOAT project
Ziemann, Christina; Rahmer, Hartmut; Escrig Vidal, A.; Bonvicini, Giuliana; Ibanez Garcia, M.J.; Monfort Gimeno, E.; Creutzenberg, Otto H.
Conference Paper, Journal Article
2015The Silicoat project: In vitro and in vivo toxicity screening of quartz varieties from ceramics industry and approaches for an effective quartz surface coating
Creutzenberg, Otto H.; Reamon-Buettner, Stella Marie; Tillmann, Thomas; Hansen, Tanja; Garcia, M.J.; Monfort, Eliseo; Bonvicini, Giuliana; Escrig, Alberto; Ziemann, Christina
Abstract
2015Single-promoter analysis of CpG and non-CpG methylation patterns in spleen of mice exposed to extremely low frequency magnetic field (ELF-MF)
Reamon-Buettner, Stella Marie; Hiemisch, Andreas; Lewin, Geertje; Dasenbrock, Clemens; Halter, Roman
Conference Paper, Journal Article
2015Species comparison of rat and human precision-cut lung slices as an alternative in risk assessment based on read-across approach
Danov, Olga; Escher, Sylvia E.; Schröder, Katrin; Vorgrimmler, David; Bersch, Claus; Braubach, Peter; Jonigk, Danny; Pfennig, Olaf; Warnecke, Gregor; Braun, Armin; Sewald, Katherina
Abstract
2015Spontaneous nonneoplastic lesions in control syrian hamsters in three 24-month long-term carcinogenicity studies
McInnes, Elizabeth F.; Ernst, Heinrich; Germann, Paul-Georg
Journal Article
2015Streptococcus pneumoniae triggers progression of pulmonary fibrosis through pneumolysin
Knippenberg, Sarah; Ueberberg, Bianca; Maus, Regina; Bohling, Jennifer; Ding, Nadine; Tort Tarres, Meritxell; Hoymann, Heinz-G.; Jonigk, Danny; Izykowski, Nicole; Paton, James C.; Ogunniyi, Abiodun D.; Lindig, Sandro; Bauer, Michael; Welte, Tobias; Seeger, Werner; Guenther, Andreas; Sisson, H. Thomas; Gauldie, Jack; Kolb, Martin; Maus, Ulrich A.
Journal Article
2015Streptococcus pneumoniae triggers progression of pulmonary fibrosis through pneumolysin
Knippenberg, Sarah; Ueberberg, Bianca; Maus, Regina; Bohling, Jennifer; Ding, Nadine; Tort Tarres, Meritxell; Hoymann, Heinz-G.; Jonigk, Danny; Izykowski, Nicole; Paton, James C.; Ogunniyi, Abiodun D.; Lindig, Sandro; Bauer, Michael; Welte, Tobias; Seeger, Werner; Guenther, Andreas; Sisson, H. Thomas; Gauldie, Jack; Kolb, Martin; Maus, Ulrich A.
Abstract
2015Structural features of endocrine active chemicals - a comparison of in vivo and in vitro data
Lewin, Geertje; Escher, Sylvia E.; Burg, Bart van der; Simetska, Nelly; Mangelsdorf, Inge
Journal Article
2015Support for the use of computer-based predictions like quantitative structure-activity relationships (QSAR methods) to avoid animal testing under REACH
Escher, Sylvia; Batke, Monika; Arning, Jürgen; Brandt, Marc; Kupper, Jürgen; Eifert, Harald; Wibbertmann, Axel
Abstract
2015Targeted expression profiling of single disseminated cancer cells isolated from bone marrow of prostate cancer patients
Guzvic, M.; Braun, B.; Ganzer, R.; Burger, M.; Nerlich, M.; Winkler, S.; Werner-Klein, M.; Czyz, Z.T.; Polzer, B.; Klein, C.A.
Abstract
2015Tiotropium respimat: Comparison of bronchodilator efficacy of 5 and 2.5 µg doses
Hohlfeld, Jens M.; Calverley, P.; Könen-Bergmann, M.; Metzdorf, N.; Bell, S.
Abstract
2015Translational models for acute respiratory injury and inflammation using precision cut lung slices
Sewald, Katherina
Abstract
2015TRPA1 agonists modulate the trachealis muscle tone via two independent mechanisms
Haider, Georg; Lee, Jae Hwa; Wiegand, Silke; Spies, Emma; Hoymann, Heinz-Gerd; Kummer, Wolfgang; Braun, Armin; Nassenstein, Christina
Abstract
2015TRPA1-Agonists: Novel bronchodilators?
Haider, G.; Lee, J.-H.; Wiegand, S.; Spies, E.; Hoymann, H.-G.; Kummer, W.; Braun, A.; Nassenstein, C.
Journal Article
2015TTC concept: Non-oral routes and influence of local effects
Escher, Sylvia E.
Abstract
2015Update of time extrapolation factors for risk assessment: The benefit of combined databases and probabilistic analyses
Escher, Sylvia E.; Hoffmann-Doerr, Simone; Pastor, Manuel; Partosch, Falko; Schröder, Katrin; Mangelsdorf, Inge
Abstract
2015The use of AOPs in risk assessment: Development of biomarker based on a read across use case on VPA analogues in the Detective project
Stöber, Werner; Steger-Hartmann, Thomas; Myatt, Glenn J.; Richarz, Andrea; Hengstler, Jan; Escher, Sylvia E.
Abstract
2015Use of ex vivo organotypic lung tissue in translational research of respiratory injury and inflammation diseases
Sewald, Katherina
Abstract
2015VPA Read across: Development of predictive biomarkers by using toxicity data of structurally similar compounds
Stöber, Regina; Escher, Sylvia E.; Hengstler, Jan G.
Abstract
20141. Welche Auswirkung hat "Hungern" in Toxizitätsstudien mit wiederholter Verabreichung? 2. Prädiktivität von Organgewichten - Organgewicht als Biomarker in der Toxikologie?
Schweiger, Julietta Ursula
: Escher, Sylvia (1. Gutachter); Stahlmann, Ralf (2. Gutachter)
Master Thesis
2014Airway hyper-responsiveness in lipopolysaccharide-challenged common marmosets (Callithrix jacchus)
Curths, Christoph; Wichmann, Judy; Dunker, Sarah; Windt, Horst; Hoymann, Heinz-Gerd; Lauenstein, Hans D.; Hohlfeld, Jens M.; Becker, Tamara; Kaup, Franz-Josef; Braun, Armin; Knauf, Sascha
Journal Article
2014Allergic airway inflammation induces the migration of dendritic cells into airway sensory ganglia
Le, D.D.; Rochlitzer, S.; Fischer, A.; Heck, S.; Tschernig, T.; Sester, M.; Bals, R.; Welte, T.; Braun, A.; Dinh, Q.T.
Journal Article
2014Allergische Atemwegsentzündung induziert eine Zunahme von Dendritischen Zellen in den Atemwegsganglien der Maus
Le, Duc Dung; Rochlitzer, Sabine; Heck, Sebastian; Bals, Robert; Braun, Armin; Welte, Tobias; Dinh, Quoc Thai
Abstract
2014Alternative model for repeated dose inhalation toxicity using precision-cut lung slices
Neuhaus, Vanessa; Danov, Olga; Witte, J.; Romberg, Susanne; Escher, Sylvia; Schaudien, Dirk; Braun, Armin; Sewald, Katherina
Abstract
2014Analysing reproductive toxicity studies using the FeDTex database - does an F2-generation provide an additional benefit?
Schulz, Florian; Lewin, Geertje; Mangelsdorf, Inge; Batke, Monika; Escher, Sylvia
Journal Article, Conference Paper
2014Analysis of nucleic acids in single cells
Kirsch, Stefan; Polzer, Bernhard; Klein, Christoph A.
Book Article
2014Analyzing dermal absorption data of chemicals
Scholz, Roland; Hahn, Stefan; Bitsch, Annette
Journal Article, Conference Paper
2014Applications of lp-norms and their smooth approximations for gradient based learning vector quantization
Lange, M.; Zühlke, D.; Holz, O.; Villmann, T.
Conference Paper
2014Applications of NMR techniques for the identification and structure elucidation of emerging organic and other xenobiotic organic contaminants
Preiß, Alfred; Godejohann, Markus
Book Article
2014Assessment of immunotoxicity induced by chemicals in human precision-cut lung slices (PCLS)
Lauenstein, L.; Switalla, S.; Prenzler, F.; Seehase, S.; Pfennig, O.; Förster, C.; Fieguth, H.; Braun, A.; Sewald, K.
Journal Article
2014Biological effects of inhalable compounds improvements of the in vitro testing method
Ritter, Detlef; Knebel, Jan; Brodbeck, Carsten; Javala, Pasi
Abstract
2014Biological effects of inhalable substances - development of a concept to standardize in vitro studies using aerosols
Ritter, Detlef; Arndt, Hendrik; Knebel, Jan
Journal Article, Conference Paper
2014Biological impact of modified inhalable carbon black nanoparticles assessed in cell and tissue culture models
Danov, Olga; Kopf, Johannes; Ströbele, M.; Bockhorn, H.; Fehrenbach, H.; Braun, Armin; Sewald, Katherina; Hansen, Tanja
Abstract
2014Biomarker for eosinophil and T-cell recruitment induced by interleukin-13 as a therapeutic target for allergic asthma tested in human precision-cut lung slices
Danov, Olga; Jiménez Delgado, Sharon Melissa; Drake, H.; Pfennig, Olaf; Förster, C.; Hohlbaum, A.; Audoly, L.; Braun, Armin; Sewald, Katherina
Abstract
2014Biotechnologie statt Tierversuche
Braun, Armin
Journal Article
2014BrdU screening - a short-time test for reliable prediction of carcinogenicity for MWCNT
Hackbarth, Anja; Schaudien, Dirk; Bellmann, Bernd; Ernst, Heinrich; Leonhardt, Albrecht; Heinrich, Uwe; Rittinghausen, Susanne
Abstract
2014BrdU screening - short-time test for reliable prediction of carcinogenicity for MWCNT
Hackbarth, Anja; Schaudien, Dirk; Bellmann, Bernd; Ernst, Heinrich; Leonhardt, Albrecht; Steinberg, Pablo; Rittinghausen, Susanne
Journal Article, Conference Paper
2014Building up a co-culture and surfactant model for routine use in ali exposures
Javala, Pasi; Ritter, Detlef; Knebel, Jan
Abstract
2014The carcinogenic effect of various multi-walled carbon nanotubes (MWCNTs) after intraperitoneal injection in rats
Rittinghausen, Susanne; Hackbarth, Anja; Creutzenberg, Otto; Ernst, Heinrich; Heinrich, Uwe; Leonhardt, Albrecht; Schaudien, Dirk
Journal Article
2014Carcinogenicity and mutagenicity of nanoparticles - assessment of current knowledge as basis for regulation
Schröder, Katrin; Polenz-Michel, Christina; Simetska, Nelly; Voss, Jens-Uwe; Escher, Sylvia; Mangelsdorf, Inge
Report
2014CEFIC-LRI N1 project: Genotoxicity of a synthetic amorphous silica (SAS) in rats
Knebel, Jan; Ziemann, Christina; Creutzenberg, Otto H.
Abstract
2014CEFIC-LRI N1 Project: Inhalation toxicity of a synthetic amorphous silica (SAS) in rats
Creutzenberg, Otto H.; Pohlmann, Gerhard; Hansen, Tanja; Schuchardt, Sven; Ernst, Heinrich; Tillmann, Thomas; Schaudien, Dirk
Abstract
2014CEFIC-LRI N1 Project: Oral toxicity of a synthetic amorphous silica (SAS) in rats
Buschmann, Jochen; Lewin, Geertje; Creutzenberg, Otto H.
Abstract
2014Cell counting in human endobronchial biopsies - disagreement of 2D versus 3D morphometry
Bratu, Vlad A.; Erpenbeck, Veit J.; Fehrenbach, Antonia; Rausch, Tanja; Rittinghausen, Susanne; Krug, Norbert; Hohlfeld, Jens M.; Fehrenbach, Heinz
Journal Article
2014Characterization of ex vivo immunostimulated dendritic cells in murine lung tissue
Brandstetter, Ronja Lorena
: Braun, Armin (1. Gutachter); Schwinzer, Reinhard (2. Guterachter)
Master Thesis
2014Characterization of IL-13- and allergen-induced airway hyperreactivity in precision-cut lung slices of different species
Drake, Helena
: Förster, Irmgard (Supervisor); Burgdorf, Sven (Supervisor); Sewald, Katherina (Adviser); Braun, Armin (Adviser)
Master Thesis
2014The ChemScreen project to design a pragmatic alternative approach to predict reproductive toxicity of chemicals
Burg, B. van der; Bay Wedebye, E.; Dietrich, D.R.; Jaworska, J.; Mangelsdorf, Inge; Paune, E.; Schwarz, M.; Piersma, A.H.; Kroese, E.D.
Abstract
2014Combined genome and transcriptome analysis of single disseminated cancer cells from bone marrow of prostate cancer patients reveals unexpected transcriptomes
Guzvic, Miodrag; Braun, Bernhard; Ganzer, Roman; Burger, Maximilian; Nerlich, Michael; Winkler, Sebastian; Werner-Klein, Melanie; Czyz, Zbigniew T.; Polzer, Bernhard; Klein, Christoph A.
Journal Article
2014Comparison of two different application routes of nanosilver in rats - a toxicokinetic study
Horzowski, Sabine; Lichtenstein, Dajana; Potkura, Jana; Oberemm, Axel; Creutzenberg, Otto; Lampen, Alfonso
Abstract
2014Correlations between different endpoints in repeated dose toxicity studies: Occurrence of dependent and independent effects at equal dose levels in the RepDose and the "ELINCS" database
Batke, Monika; Bitsch, Annette; Gundert-Remy, Ursula; Gütlein, Martin; Kramer, Stefan; Partosch, Falko; Seeland, Madeleine; Stahlmann, Ralf
Journal Article, Conference Paper
2014Cytochrome P450 monooxygenases expression in human bronchial epithelial calu-3 cells under different culture conditions
Hansen, Tanja; Niehof, Monika; Knebel, Jan
Abstract
2014Data-mining in toxicology
Mangelsdorf, I.
Book Article
2014Dermal exposure
Mangelsdorf, Inge; Schröder, Katrin; Costa Pinheiro, Nathalie
Book
2014Development of an in silico pre-screen for reproductive toxicity within the EU project ChemScreen
Lewin, Geertje; Burg, Bart van der; Batke, Monika; Escher, Sylvia; Mangelsdorf, Inge
Journal Article, Conference Paper
2014Development of chemical categories by optimized clustering strategies
Batke, Monika; Bitsch, Annette; Gundert-Remy, Ursula; Gütlein, Martin; Helma, Christoph; Kramer, Stefan; Maunz, Andreas; Partosch, Falko; Seeland, Madeleine; Stahlmann, Ralf
Journal Article, Conference Paper
2014Diamide does not improve the analysis of IL1b and TNFa in dithiothreitol-treated sputum supernatants
Holz, Olaf; Lavae-Mokhtari, Bianca; Witte, Lena; Hohlfeld, Jens Michael
Abstract
2014Distribution of ciliated epithelial cells in the trachea of common marmosets (Callithrix jacchus)
Hoffmann, R.; Braun, A.; Knauf, S.; Kaup, F.-J.; Bleyer, M.
Journal Article
2014Does foam application reduce aerosol formation?
Bitsch, Annette; Schwarz, Katherina; Hahn, Stefan; Ehni, M.; Holthenrich, D.; Koch, W.
Abstract
2014Dose-range finding of natural birch pollen exposure in patients with seasonal allergic rhinitis in the Fraunhofer Environmental Challenge Chamber
Lüer, Katrin; Windt, Horst; Schwarz, Katharina; Badorrek, Philipp; Sebastian, Ramona; Haefner, Dietrich; Koch, Wolfgang; Krug, Norbert; Hohlfeld, Jens Michael
Abstract
2014The effect of controlled exposure to grass pollen in an environmental challenge chamber on dermal symptoms in patients with atopic dermatitis
Heratizadeh, Annice; Badorrek, Philipp; Niebuhr, Margarete; Erpenbeck, Veit Johannes; Lösche, C.; Krug, Norbert; Hohlfeld, Jens Michael; Werfel, Thomas
Abstract
2014The effect of flow rate on the level of volatile organic compounds (voc) in exhaled breath
Holz, Olaf; Gaida, Arne; Schuchardt, Sven; Langejuergen, Jens; Zimmermann, Stefan; Hohlfeld, Jens Michael
Abstract
2014Effect of sample processing on the analysis of IL4, IL5, and IL13 in sputum supernatants
Holz, Olaf; Müller, Meike; Ignatenko, Stanislav; Kappeler, Dominik; Buhl, Roland; Beeh, Kai-Michael; Kornmann, Oliver; Kirsten, Anne; Homburg, Ursula; Garn, Holger; Krug, Norbert; Hohlfeld, Jens Michael
Abstract
2014Effects of ultrafine particles on the allergic inflammation in the lung of asthmatics: Results of a double-blinded randomized cross-over clinical pilot study
Schaumann, Frank; Frömke, Cornelia; Dijkstra, Dorothea; Alessandrini, Francesca; Windt, Horst; Karg, Erwin; Müller, Meike; Winkler, Carla; Braun, Armin; Koch, Armin; Hohlfeld, Jens Michael; Behrendt, Heidrun; Schmid, Othmar; Koch, Wolfgang; Schulz, Holger; Krug, Norbert
Journal Article
2014Efficacy of the oral chemoattractant receptor homologous molecule on TH2 cells antagonist BI 671800 in patients with seasonal allergic rhinitis
Krug, Norbert; Gupta, Abhy; Badorrek, Philipp; Koennen, Ruediger; Mueller, Meike; Pivovarova, Anna; Hilbert, James; Wetzel, Kristiane; Hohlfeld, Jens M.; Wood, Chester
Journal Article
2014Efficiency improvement of an antibody production process by increasing the inoculum density
Hecht, V.; Duvar, S.; Ziehr, H.; Burg, J.; Jockwer, A.
Journal Article
2014Einzelzell Heterogenität von Melanomsphären generiert aus disseminierten Tumorzellen
Sadlers, Sabine Jennifer
: Rosenau, Frank (Gutachter); Polzer, Bernhard (Gutachter); Hennes, Kilian (Zweitprüfer)
Master Thesis
2014Entwicklung eines Assays zu Qualitätskontrolle von Whole Transcriptome Amplifications
Ganser, Iris
: Klein, Christoph A. (Betreuer)
Bachelor Thesis
2014Entwicklung eines Rhinovirus-Infektionsmodells in Precision-cut lung slices
Romberg, Susanne
: Lübke, Torben (Gutachter); Fischer von Mollard, Gabriele (Gutachter); Dasenbrock, Clemens (Zweitprüfer)
Master Thesis
2014Environmental risk assessment of veterinary pharmaceuticals
Könnecker, Gustav; Krome, Kristin
Journal Article
2014Establishment of a saline lavage model in the isolated perfused rat lung
Walter, Dorothee; Fischer, Monika; Dasenbrock, Clemens
Abstract
2014Establishment of pathway-specific gene expression analysis using the example of the paraquat action on human lung epithelial cells
Niehof, Monika; Augustin, Christian; Hansen, Tanja
Journal Article, Conference Paper
2014Etablierung eines Modellsystems mit Aerosolen zur Charakterisierung von Expositionssystemen für die Untersuchung inhalierbarer Substanzen in vitro
Arndt, Hendrik
: Walker, Gottfried (Erstprüfer); Knebel, Jan W. (Zweitprüfer)
Bachelor Thesis
2014Etablierung eines Pseudomonas aeruginosa Biofilmassays zur Antibiotikawirksamkeitstestung
Donath, Mandy
: Schierack, Peter (Gutachter); Rochlitzer, Sabine (Gutachter)
Bachelor Thesis
2014Evaluation of small molecule FRET reporter for the diagnosis and monitoring of proteolytic activity in a chronic obstructive lung disease model
Reither, G.; Heath, N.; Holz, Olaf; Kahn, N.; Hohlfeld, Jens Michael; Schulz, C.; Mall, M.A.
Abstract
2014The evaluation of the biopersistence, pathological response, and pleural translocation of chrysotile containing brake dust in comparison to crocidolite asbestos following short-term inhalation exposure
Bernstein, David M.; Rogers, R.A.; Ernst, Heinrich; Phillips, J.I.
Abstract
2014Evaluation of the deposition, translocation and pathological response of brake dust with and without added chrysotile in comparison to crocidolite asbestos following short-term inhalation: Interim results
Bernstein, David M.; Rogers, Rick; Sepulveda, Rosalina; Kunzendorf, Peter; Bellmann, Bernd; Ernst, Heinrich; Phillips, James I.
Journal Article
2014Ex vivo models for asthma, COPD and lung injury in precision cut lung slices (PCLS)
Sewald, Katherina; Braun, Armin
Abstract
2014Exercise challenge amplifies differences in metabolomic signals between healthy smokers and smokers with COPD (gold2)
Holz, Olaf; Roepcke, Stefan; Lauer, Gereon; Elmlinger, Martin; Lahu, Gezim; Hohlfeld, Jens Michael
Abstract
2014Fraunhofer-Institut für Toxikologie und Experimentelle Medizin. Leistungen und Ergebnisse. Jahresbericht 2013
 
Annual Report
2014Frühe Phase der Allergen-induzierten Atemwegsreaktion beim Weißbüschelaffen nach passiver Sensibilisierung von Lungengewebe mit humanem Blutplasma
Wichmann, Judy; Jiménez Delgado, Sharon Melissa; Curths, Christoph; Becker, Tamara; Kaup, Franz Josef; Braun, Armin; Sewald, Katherina; Knauf, Sascha
Abstract
2014Fundamental improvements of the air-liquid interface technique for use in in vitro inhalation toxicology
Knebel, Jan; Ritter, Detlef; Brodbeck, Carsten
Abstract
2014Gastrointestinal absorption processes of substances: Do they have an impact on bioaccumulation?
Zwintscher, Ariane; Hahn, Stefan; Kühne, R.; Schuurmann, G.; Drost, W.; Ackermann, J.; Joehncke, U.; Schlechtriem, C.; Nendza, M.
Abstract
2014Genomic high-resolution profiling of single CKpos/CD45neg flow-sorting purified circulating tumor cells from patients with metastatic breast cancer
Neves, Rui P.L.; Raba, Katharina; Schmidt, Oliver; Honisch, Ellen; Meier-Stiegen, Franziska; Behrens, Bianca; Möhlendick, Birte; Fehm, Tanja; Neubauer, Hans; Klein, Christoph A.; Polzer, Bernhard; Sproll, Christoph; Fischer, Johannes C.; Niederacher, Dieter; Stoecklein, Nikolas H.
Journal Article
2014Histopathological analysis of malignant tumors induced by intraperitoneal injection of carbon nanotubes
Rittinghausen, Susanne; Bellmann, Bernd; Hackbarth, Anja; Ernst, Heinrich; Heinrich, Uwe; Leonhardt, A.; Schaudien, Dirk
Abstract
2014A human in vitro allergy model showing allergen specific immune responses using house dust mite or grass pollen allergen
Müller, Meike; Schaumann, Frank; Braun, Armin
Abstract
2014Human medicinal products: Environmental risk assessment for volatile anaesthetics
Krome, Kristin; Hahn, Stefan; Schwonbeck, Susanne; Könnecker, Gustav; Licht, Oliver
Journal Article, Conference Paper
2014Human organotypic cancer model
Konzok, Sebastian; Schindler, Susann; Braun, Armin; Sewald, Katherina
Abstract
2014Identification and quantification of basophils in the airways of asthmatics following segmental allergen challenge
Dijkstra, D.; Hennig, C.; Hansen, G.; Biller, H.; Krug, N.; Hohlfeld, J.M.
Journal Article
2014Identifying placental epigenetic alterations in an intrauterine growth restriction (IUGR) rat model induced by gestational protein deficiency
Reamon-Büttner, Stella Marie; Buschmann, Jochen; Lewin, Geertje
Journal Article
2014IL-13 induced asthma model in human precision-cut lung slices
Danov, Olga; Jiménez Delgado, Sharon Melissa; Drake, H.; Seehase, Sophie; Hohlbaum, A.M.; Bersch, C.; Jonigk, D.; Warnecke, G.; Braun, Armin; Sewald, Katherina
Abstract
2014Immune humanization of immunodeficient mice using diagnostic bone marrow aspirates from carcinoma patients
Werner-Klein, Melanie; Proske, Judith; Werno, Christian; Schneider, Katharina; Hofmann, Hans-Stefan; Rack, Brigitte; Buchholz, Stefan; Ganzer, Roman; Blana, Andreas; Seelbach-Göbel, Birgit; Nitsche, Ulrich; Männel, Daniela N.; Klein, Christoph A.
Journal Article
2014Impact of a Met(11)Thr single nucleotide polymorphism of surfactant protein D on allergic airway inflammation in a murine asthma model
Winkler, C.; Bahlmann, O.; Viereck, J.; Knudsen, L.; Wedekind, D.; Hoymann, H.G.; Madsen, J.; Thum, T.; Hohlfeld, J.M.; Ochs, M.
Journal Article
2014Impact of endobronchial allergen provocation on macrophage phenotype in asthmatics
Winkler, C.; Witte, L.; Moraw, N.; Faulenbach, C.; Müller, M.; Holz, O.; Schaumann, F.; Hohlfeld, J.M.
Journal Article
2014Improvement of the TTC concept for oral and inhalation exposure and its application in an Integrated Testing Strategy (ITS) for the endpoint repeated-dose toxicity
Tluczkiewicz, Inga
: Schüürmann, Gerrit (Supervisor); Escher, Sylvia (Advisor)
Dissertation
2014Improvements of the ALI in vitro testing method for inhalable compounds
Ritter, Detlef; Knebel, Jan; Brodbeck, Carsten
Abstract
2014Incorporating potency into EU classification for carcinogenicity and reproductive toxicity
Hennes, C.; Batke, Monika; Bomann, W.; DuHayon, S.; Kosemund, K.; Politano, V.; Stinchcombe, S.; Doe, J.
Journal Article
2014Inhalation toxicity of nanoparticle-based aerosols
Gessner, Isabel
: Mathur, Sanjay (Betreuer); Knebel, Jan W. (Betreuer); Dasenbrock, Clemens (Zweitprüfer)
Master Thesis
2014Interleukin-13 as a therapeutic target for allergic asthma tested in human precision-cut lung slices
Danov, Olga; Jiménez Delgado, Sharon Melissa; Pfennig, Olaf; Forster, Christine; Hohlbaum, Andreas; Audoly, Laurent; Braun, Armin; Sewald, Katherina
Abstract
2014Invasion, proliferation and influence of cancer cell line MDA-MB-231 on organotypic tissue using Precision Cut Lung Slices (PCLS)
Konzok, Sebastian
: Braun, Armin (Supervisor); Tamura-Niemann, Teruko (Supervisor)
Master Thesis
2014Invasive but repetitive lung function measurements in a rodent model of pulmonary fibrosis
Hoymann, Heinz-Gerd; Ernst, Heinrich; Creutzenberg, Otto H.; Schaudien, Dirk; Müller, Meike; Knudsen, Lars; Braun, Armin
Abstract
2014Investigations of the biological effects of airborne and inhalable substances by cell-based in vitro methods
Ritter, Detlef; Knebel, Jan
Journal Article
2014Isolation and cultivation of metabolically competent alveolar epithelial cells from A/J mice
Hansen, T.; Chougule, A.; Borlak, J.
Journal Article
2014A k-NN algorithm for predicting oral sub-chronic toxicity in the rat
Gadaleta, Domenico; Pizzo, Fabiola; Lombardo, Anna; Carotti, Angelo; Escher, Sylvia E.; Nicolotti, Orazio; Benfenati, Emilio
Journal Article
2014Kinetikanalysen des Aktivierungszustandes von ex vivo stimulierten dendritischen Zellen im murinen PCLS Modell
Baron, Lena
: Braun, Armin (1. Gutachter); Schwinzer, Reinhard (2. Gutachter)
Master Thesis
2014Lack of marked cyto- and genotoxicity of cristobalite in devitrified (heated) alkaline earth silicate wools in short-term assays with cultured primary rat alveolar macrophages
Ziemann, Christina; Harrison, Paul T.C.; Bellmann, Bernd; Brown, Robert C.; Zoitos, Bruce K.; Class, Philippe
Journal Article
2014Longitudinal measurement of airway inflammation over one year in children and adults with intermittent asthma
Holz, Olaf; Pedersen, Frauke; Kanniess, Frank; Zielen, Stefan; Gillissen, Adrian; Berg, Andrea von; Berdel, Dietrich; Schnoor, Maike; Magnussen, Helgo
Abstract
2014Longitudinal measurement of airway inflammation over one year in children and adults with intermittent asthma
Pedersen, F.; Holz, O.; Kanniess, F.; Zielen, S.; Schulze, J.; Gillissen, A.; Berg, A. von; Berdel, D.; Beier, J.; Beeh, K.; Schnoor, M.; Magnussen, H.
Journal Article
2014Lung function assessment in nonhuman primate models of obstructive pulmonary diseases
Curths, Christoph; Wichmann, Judy; Becker, Tamara; Kaup, Franz-Josef; Hohlfeld, Jens Michael; Windt, Horst; Dunker, Sarah; Hoymann, Heinz-Gerd; Braun, Armin; Knauf, Sascha
Abstract
2014Lung function assessment in the common marmoset (Callithrix jacchus) for the evaluation of translational nonhuman primate models of lung inflammation
Curths, Christoph; Wichmann, Judy; Becker, Tamara; Kaup, Franz Josef; Hohlfeld, Jens Michael; Windt, Horst; Dunker, Sarah; Hoymann, Heinz Gerd; Braun, Armin; Knauf, Sascha
Abstract
2014Lung tissue culture model for assessment of cytotoxicity and inflammation induced by inhalable carbon black nanoparticles
Braun, Armin; Danov, Olga; Kopf, Johannes Claudius; Ströbele, Michael; Hansen, Tanja; Fehrenbach, Heinz; Sewald, Katherina
Abstract
2014Lymph nodes
Kuper, Frieke C.; Schaudien, Dirk; Parker, George
Book Article
2014Lymphoid tissue and pathological influences of toxicants
Schaudien, Dirk; Harleman, H.; Bouallala, F.; Kuper, C.F.
Book Article
2014A model of neuronal hyperreactivity in passive sensitized human organotypic tissue
Schindler, Susann; Jiménez Delgado, Sharon Melissa; Braun, Armin
Abstract
2014Molecular profiling of single circulating tumor cells with diagnostic intention
Polzer, Bernhard; Medoro, Gianni; Pasch, Sophie; Fontana, Francesca; Zorzino, Laura; Pestka, Aurelia; Andergassen, Ulrich; Meier-Stiegen, Franziska; Czyz, Zbigniew T.; Alberter, Barbara; Treitschke, Steffi; Schamberger, Thomas; Sergio, Maximilian; Bregola, Giulia; Doffini, Anna; Gianni, Stefano; Calanca, Alex; Signorini, Giulio; Bolognesi, Chiara; Hartmann, Arndt; Fasching, Peter A.; Sandri, Maria T.; Rack, Brigitte; Fehm, Tanja; Giorgini, Guiseppe; Manaresi, Nicolò; Klein, Christoph A.
Journal Article
2014Multi-Label-Classification to predict repeated dose toxicity in the context of REACH
Batke, Monika; Bitsch, Annette; Gundert-Remy, Ursula; Gütlein, Martin; Helma, Christoph; Kramer, Stefan; Maunz, Andreas; Partosch, Falko; Seeland, Madeleine; Stahlmann, Ralf
Journal Article, Conference Paper
2014Multiwalled carbon nanotubes (MWCNT) induce DNA damage and cellular senescence in human peritoneal mesothelial LP9 cells
Reamon-Büttner, Stella Marie; Bellmann, Bernd; Hackbarth, Anja; Leonhardt, Albrecht; Niehof, Monika; Ziemann, Christina
Journal Article, Conference Paper
2014Murine precision-cut liver slices (PCLS): A new tool for studying tumor microenvironments and cell signaling ex vivo
Koch, Alexandra; Saran, Shashank; Tran, Doan Duy Hai; Klebba-Färber, Sabine; Thiesler, Hauke; Sewald, Katherina; Schindler, Susann; Braun, Armin; Klopfleisch, Robert; Tamura, Teruko
Journal Article
2014Nanoparticles and pop-off technique for electron microscopy: A known technique for a new purpose
Lehmbecker, Annika; Rittinghausen, Susanne; Rohn, Kerstin; Baumgärtner, Wolfgang; Schaudien, Dirk
Journal Article
2014Neuronale Plastizität in NGF-transgenen Mäusen bei allergischen Atemwegentzündungen
Dinh, Quoc Thai; Quarcoo, David; Braun, Armin; Welte, Tobias; Bals, Robert; Fischer, A.
Abstract
2014A new adjuvanted nanoparticle-based H1N1 influenza vaccine induced antigen-specific local mucosal and systemic immune responses after administration into the lung
Neuhaus, Vanessa; Chichester, Jessica A.; Ebensen, Thomas; Schwarz, Katharina; Cartman, Caitlin E.; Shoji, Yoko; Guzman, Carlos A.; Yusibov, Vidadi; Sewald, Katherina; Braun, Armin
Journal Article
2014New treatment strategies for respiratory diseases: Ex vivo and in vivo evaluation of pharmacological immunomodulations using a nanoparticle-based drug delivery system
Neuhaus, Vanessa
: Braun, Armin (Supervisor); Dittrich, Anna-Maria (Cosupervisor); Müller-Goymann, Christel (Cosupervisor)
Dissertation
2014No exacerbation but impaired anti-viral mechanisms in a rhinovirus-chronic allergic asthma mouse model
Rochlitzer, Sabine; Hoymann, Heinz-Gerd; Müller, Meike; Braun, Armin
Journal Article
2014Numerical study of the RespiCon sampler performance in the calm air
Zaripov, S.; Koch, W.
Journal Article
2014Omalizumab in patients with allergic (IgE-mediated) asthma and IgE/bodyweight combinations above those in the initially approved dosing table
Kornmann, Oliver; Watz, Henrik; Fuhr, Rainard; Krug, Norbert; Erpenbeck, Veit J.; Kaiser, Guenther
Journal Article
2014Optimizing gene-expression analysis for induced sputum
Holz, Olaf; Hansen, Tanja; Homburg, Ursula; Garn, Holger; Hohlfeld, Jens Michael; Niehof, Monika
Abstract
2014Passively sensitized precision-cut lung slices from marmoset monkeys as a preclinical assay to test novel IgE inhibitors
Wichmann, Judy; Jiménez Delgado, Sharon Melissa; Curths, Christoph; Becker, Tamara; Eggel, Alexander; Kaup, Franz-Josef; Braun, Armin; Sewald, Katherina; Knauf, Sascha
Abstract
2014Pharmacokinetics and pharmacodynamics of tiotropium solution and tiotropium powder in chronic obstructive pulmonary disease
Hohlfeld, Jens M.; Sharma, A.; Noord, J.A. van; Cornelissen, P.J.; Derom, E.; Towse, L.; Peterkin, V.; Disse, B.
Journal Article
2014Phase-contrast MRI for detection of mild systemic hemodynamic response after segmental allergen challenge in asthmatic patients
Hinrichs, Jan; Schaumann, Frank; Renne, Julius; Schönfeld, Christian; Faulenbach, Cornelia; Winkler, Carla; Gutberlet, Marcel; Krug, Norbert; Wacker, Frank; Hohlfeld, Jens M.; Vogel-Claussen, Jens
Journal Article
2014Potential prognostic value of biomarkers in lavage, sputum and serum in a five year clinical follow-up of smokers with and without COPD
Holz, Olaf; Waschki, Benjamin; Roepcke, Stefan; Watz, Henrik; Lauer, Gereon; Faulenbach, Cornelia; Hohlfeld, Jens M.
Journal Article
2014Pre-validation of the ex vivo model precision-cut lung slices (PCLS) for prediction of acute inhalation toxicity
Sewald, Katherina; Lauenstein, Lan; Schneider, X.; Pirow, R.; Steinfath, M.; Ma-Hock, L.; Liebsch, M.; Landsiedel, R.; Braun, Armin; Martin, C.
Abstract
2014Precision-cut lung slices as alternative to mimic inflammation, lung injury and bronchoconstriction after short and long-term maintenance in culture
Neuhaus, Vanessa; Schaudien, Dirk; Sewald, Katherina; Braun, Armin
Abstract
2014Predicted no effect concentration derivation as a significant source of variability in environmental hazard assessments of chemicals in aquatic systems: An international analysis
Hahn, Torsten; Diamond, Jerry; Doubson, Stuart; Howe, Paul; Kielhorn, Janet; Könnecker, Gustav; Lee-Steere, Chris; Mangelsdorfg, Inge; Schneider, Uwe; Sugaya, Yoshio; Taylor, Ken; Van Dam, Rick; Stauber, Jenny L.
Journal Article
2014Prevalence and phenotypic characteristics of severe adult-onset asthma in the U-Biopred cohort
Hekking, Pieter-Paul; Wagener, Ariane H.; Sousa, Ana R.; Fowler, Stephen J.; Bakke, Per; Frey, Urs; Krug, Norbert; Hashimoto, Simone; Woodcock, Ashley; Chanez, Pascal; Montuschi, Paolo; Bisgaard, Hans; Corfield, Julie; Howarth, Peter H.; Djukanovic, Ratko; Chung, Kian Fan; Fleming, Louise; Riley, John; Jeyasingham, Elisabeth; Fichtner, Klaus; Rowe, Anthony; Roberts, Graham; Singer, Florian; Geiser, Thomas; Horvath, Ildiko; Riccardo, Polosa; Vissing, Nadja H.; Dahlen, Babro; Musial, Jacek; Murray, Clare S.; Myles, David; Compton, Chris; Higenbottam, Tim W.; Vestbo, J.; Pahus, Laurie; Larsson, Lars; Sandstrom, Thomas; Shaw, Dominic; Wagers, Scott S.; Sterk, Peter J.; Bansal, Aruna T.; Bel, Elisabeth
Abstract
2014Prevalidation of the ex vivo model PCLS for the prediction of acute inhalation toxicity
Sewald, Katherina; Hess, A.; Lauenstein, Lan; Schneider, X.; Vogel, S.; Steinfath, M.; Pirow, R.; Liebsch, M.; Kolle, S.; Ma-Hock, L.; Landsiedel, R.; Martin, C.; Braun, Armin
Abstract
2014Promises and challenges in constructing an adverse outcome pathway for chemical sensitization of the respiratory tract
Sullivan, K.; Cochrane, S.; Enoch, S.; Kimber, I.; Patlewicz, G.; Roggen, E.; Sewald, Katherina; Ezendam, J.
Abstract
2014Prostaglandin D2-supplemented "functional eicosanoid testing and typing" assay with peripheral blood leukocytes as a new tool in the diagnosis of systemic mast cell activation disease
Schäfer, Dirk; Dreßen, Peter; Brettner, Stefan; Rath, Norbert-Folke; Molderings, Gerhard J.; Jensen, Katrin; Ziemann, Christina
Journal Article
2014Quantification of pulmonary inflammation after segmental allergen challenge using turbo-inversion recovery-magnitude magnetic resonance imaging
Vogel-Claussen, Jens; Renne, Julius; Hinrichs, Jan; Schönfeld Christian; Gutberlet, Marcel; Schaumann, Frank; Winkler, Carla; Faulenbach, Cornelia; Krug, Norbert; Wacker, Frank; Hohlfeld, Jens Michael
Journal Article
2014Quantitative measurement of melanoma spread in sentinel lymph nodes and survival
Ulmer, A.; Dietz, K.; Hodak, I.; Polzer, B.; Scheitler, S.; Yildiz, M.; Czyz, Z.; Lehnert, P.; Fehm, T.; Hafner, C.; Schanz, S.; Röcken, M.; Garbe, C.; Breuninger, H.; Fierlbeck, G.; Klein, C.A.
Journal Article
2014Refinement of acute inhalation toxicity studies: The isolated perfused rat lung as a screening tool for surface-active substances
Fischer, Monika; Dasenbrock, Clemens; Windt, Horst; Koch, Wolfgang
Journal Article, Conference Paper
2014Refinement of acute inhalation toxicity studies: The isolated perfused rat lung as a screening tool for surface-active substances
Dasenbrock, Clemens; Fischer, Monika; Windt, Horst; Koch, Wolfgang
Abstract
2014Reliable single cell array CGH for clinical samples
Czyz, Zbigniew T.; Hoffmann, Martin; Schlimok, Günter; Polzer, Bernhard; Klein, Christoph A.
Journal Article
2014Reprogramming of COPD lung fibroblasts through formation of induced pluripotent stem cells (iPSCs)
Basma, H.; Gunji, Y.; Iwasawa, S.; Nelson, A.; Farid, M.; Ikari, J.; Liu, X.; Wang, X.; Michalski, J.; Smith, L.M.; Iqbal, J.; El Behery, R.; West, W.; Yelamanchili, S.; Rennard, D.; Holz, O.; Mueller, K.-C.; Magnussen, H.; Rabe, K.F.; Castaldi, P.J.; Rennard, S.I.
Journal Article
2014Respiratory Animal Models in the Common Marmoset (Callithrix jacchus)
Curths, Christoph; Knauf, Sascha; Kaup, Franz-Josef
Journal Article
2014Reversible addition of the OH radical to p-cymene in the gas phase: Multiple adduct formation. Part 2
Alarcon, P.; Bohn, B.; Zetzsch, C.; Rayez, M.T.; Rayez, J.C.
Journal Article
2014Rhinovirus infection in human and mouse precision cut lung slices
Rochlitzer, Sabine; Müller, Meike; Sewald, Katherina; Braun, Armin
Abstract
2014Risk mitigation measures: An important aspect of the environmental risk assessment of pharmaceuticals
Liebig, Markus; Floeter, Carolin; Hahn, Thorsten; Koch, Wolfgang; Wenzel, Andrea; Römbke, Jörg
Journal Article
2014Route to route extrapolation factors for regulatory risk assessment - a probabilistic approach
Schröder, Katrin; Hoffmann-Dörr, Simone; Mangelsdorf, Inge; Escher, Sylvia
Abstract
2014Safety and efficacy of Pur118 in the ozone challenge model
Holz, Olaf; Biller, Heike; Müller, Meike; Kane, Katie; Rosano, Molly; Hanrahan, John; Hava, David L.; Hohlfeld, Jens Michael
Abstract
2014Senescence and apoptosis block hematopoietic activation of quiescent hematopoietic stem cells with short telomeres
Wang, Jianwei; Lu, Xin; Sakk, Vadim; Klein, Christoph A.; Rudolph, Karl Lenhard
Journal Article
2014Sensitivity comparison of fish and daphnia toxicity - evaluation of ecotoxicological testing strategies and chronic fish testing
May, Martin; Drost, W.; Germer, S.; Juffernholz, T.; Hahn, Stefan
Abstract
2014Sensitivity of different generations and developmental stagesin studies on reproductive toxicity
Schulz, Florian; Batke, Monika; Mangelsdorf, Inge; Pohlenz-Michel, Christina; Simetska, Nelly; Lewin, Geertje
Journal Article
2014Severe asthma patients on oral corticosteroid therapy as a distinct phenotype: The european U-BIOPRED cohort
Chung, Kian F.; Gibeon, David; Sousa, Ana R.; Corfield, Julie; Shaw, Dominick E.; Fowler, Stephen J.; Fleming, Louise J.; Riley, John; Jeyasingham, Elisabeth; Rowe, Anthony; Fichtner, Klaus; Roberts, Graham; Bakke, Per; Garnier, Christophe von; Horvath, Ildiko; Riccardo, Polosa; Krug, Norbert; Dahlen, Barbaro; Musial, Jacek; Pahus, Laurie; Myles, David; Compton, Chris; Higenbottam, Tim W.; Montuschi, Paolo; Larsson, Lars; Sandstrom, Thomas; Wagers, Scott S.; Howarth, Peter H.; Bel, Elisabeth; Bansal, Aruna T.; Djukanovic, Ratko; Sterk, Peter J.
Abstract
2014The SILICOAT project: In vitro and in vivo toxicity screening of quartz varieties from traditional ceramics industry and approaches for an effective quartz surface coating
Ziemann, Christina; Reamon-Buettner, Stella Marie; Tillmann, Thomas; Hansen, Tanja; Ibañez, Maria Jesus; Monfort, Eliseo; Bonvicini, Giuliana; Escrig, Alberto; Creutzenberg, Otto H.
Journal Article, Conference Paper
2014Species comparison of interleukin-13 induced airway hyperreactivity in precision-cut lung slices
Danov, Olga; Jiménez Delgado, Sharon Melissa; Drake, Helena; Schindler, Susann; Pfennig, Olaf; Förster, Christine; Braun, Armin; Sewald, Katherina
Journal Article, Conference Paper
2014Toxic effects of various modifications of a nanoparticle following inhalation
Creutzenberg, Otto; Voss, Jens-Uwe; Mangelsdorf, Inge; Tillmann, Thomas; Pohlmann, Gerhard; Hansen, Tanja; Kock, Heiko; Schaudien, Dirk
Journal Article, Conference Paper
2014Toxicity testing of sildenafil base-loaded liposomes in in vitro and ex vivo models for pulmonary application
Paranjpe, Mukta; Neuhaus, Vanessa; Braun, Armin; Müller-Goymann, Christel C.
Journal Article
2014Toxicogenomics directory of chemically exposed human hepatocytes
Grinberg, Marianna; Stöber, Regina M.; Edlund, Karolina; Rempel, Eugen; Godoy, Patricio; Reif, Raymond; Widera, Agata; Madjar, Katrin; Schmidt-Heck, Wolfgang; Marchan, Rosemarie; Sachinidis, Agapios; Spitkovsky, Dimitry; Hescheler, Jürgen; Carmo, Helena; Arbo, Marcelo D.; Water, Bob van de; Wink, Steven; Vinken, Mathieu; Rogiers, Vera; Escher, Sylvia; Hardy, Barry; Mitic, Dragana; Myatt, Glenn; Waldmann, Tanja; Mardinoglu, Adil; Damm, Georg; Seehofer, Daniel; Nüssler, Andreas; Weiss, Thomas S.; Oberemm, Axel; Lampen, Alfons; Schaap, Mirjam M.; Luijten, Mirjam; Steeg, Harry van; Thasler, Wolfgang E.; Kleinjans, Jos C.S.; Stierum, Rob H.; Leist, Marcel; Rahnenführer, Jürgen; Hengstler, Jan G.
Journal Article
2014Toxicological databases: Modern tools to reduce, refine and replace animal testing
Schröder, Katrin; Simetska, Nelly; Escher, Sylvia; Mangelsdorf, Inge
Journal Article, Conference Paper
2014Toxikologische Untersuchungen von Multiwalled Carbon Nanotubes, mit und ohne Eisenkatalysator, für den Einsatz in der targeted Drug Delivery, durchgeführt an humanen Lungenepithelzellen und Hepatozyten
Requardt, Hendrik
: Eisenbarth, Eva (Erstprüferin); Hennes, Kilian (Zweitprüfer); Dasenbrock, Clemens (Betreuer); Hansen, Tanja (Betreuerin)
Master Thesis
2014TTC: A new concept for inhalation exposure
Tluczkiewicz, Inga; Batke, Monika; Kühne, Ralph; Schüürmann, Gerrit; Mangelsdorf, Inge; Escher, Sylvia
Journal Article, Conference Paper
2014TTC: A new concept for inhalation exposure
Escher, Sylvia; Tluczkiewicz, Inga; Batke, Monika; Kühne, Ralf; Ebert, Ralf-Uwe; Schüürmann, Gerrit; Mangelsdorf, Inge
Abstract
2014Untersuchung der CYP450 Expression in primären humanen Hepatozyten und Hepatozyten-ähnlichen Zellsystemen
Heiermann, Steffen
: Pfitzner, Reinhard (Erstprüfer); Niehof, Monika (Zweitprüfer)
Bachelor Thesis
2014Untersuchungen zum Wirkmechanismus von nanostrukturiertem Carbon Black mit unterschiedlicher Oberflächenbeschaffenheit
Tautenhahn, Sven
: Scharfenberg, Klaus (1. Gutachter); Hansen, Tanja (2. Gutachter); Niehof, Monika (Wiss. Betreuung)
Bachelor Thesis
2014Untersuchungen zur Emission organischer Verbindungen in der Kabinenluft nach dem Enteisen von Verkehrsflugzeugen
Rosenberger, Wolfgang; Wrbitzky, Renate; Elend, Manfred; Schuchardt, Sven
Journal Article
2014Use of rat precision-cut lung slices for long-term functional evaluation
Neuhaus, Vanessa; Braun, Armin; Sewald, Katherina
Abstract
2014Validation requirements for alternative methods in inhalation toxicology - case study of a German two phase prevalidation project
Liebsch, M.; Pirow, R.; Smirnova, L.; Tharmann, J.; Linsel, G.; Troeller, S.; Huettig, N.; Bauer, M.; Graebsch, C.; Berger-Preiß, Edith; Kock, Heiko; Oertel, Antje; Ritter, Detlef; Knebel, Jan
Abstract
2014Veränderung von MHC-II positiven Zellen der Atemwegsganglien bei chronischem Hausstaubmilben-Mausmodell und HRV1B Infektion
Funck, Ulrike; Le, Duc Dung; Rochlitzer, Sabine; Heck, Sebastian; Bals, Robert; Braun, Armin; Welte, Tobias; Dinh, Quoc Thai
Abstract