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2021 | Bioaccumulation assessment of nanomaterials using freshwater invertebrate species Kuehr, Sebastian; Kosfeld, Verena; Schlechtriem, Christian | Journal Article |
2021 | Bioreactor-based antigen production process using the baculovirus expression vector system Harnischfeger, J.; Käßer, L.; Zitzmann, J.; Salzig, D.; Czermak, P. | Book Article |
2021 | Current State and Future Expectations of Translational Modeling Strategies to Support Drug Product Development, Manufacturing Changes and Controls: A Workshop Summary Report Pepin, X.J.H.; Parrott, N.; Dressman, J.; Delvadia, P.; Mitra, A.; Zhang, X.; Babiskin, A.; Kolhatkar, V.; Suarez-Sharp, S. | Journal Article |
2021 | The discovery of novel antitrypanosomal 4-phenyl-6-(pyridin-3-yl)pyrimidines Robinson, W.J.; Taylor, A.E.; Lauga-Cami, S.; Weaver, G.W.; Arroo, R.R.J.; Kaiser, M.; Gul, S.; Kuzikov, M.; Ellinger, B.; Singh, K.; Schirmeister, T.; Botana, A.; Eurtivong, C.; Bhambra, A.S. | Journal Article |
2021 | Effects of Thermal Stress on the Gut Microbiome of Juvenile Milkfish (Chanos chanos) Hassenrück, Christiane; Reinwald, Hannes; Kunzmann, Andreas; Tiedemann, Inken; Gärdes, Astrid | Journal Article |
2021 | Improved degradation of azo dyes by lignin peroxidase following mutagenesis at two sites near the catalytic pocket and the application of peroxidase-coated yeast cell walls Ilić Đurđić, K.; Ostafe, R.; Prodanovic, O.; Đurđević Đelmaš, A.; Popović, N.; Fischer, R.; Schillberg, S.; Prodanovic, R. | Journal Article |
2021 | Lipidomic analysis of local inflammation models shows a specific systemic acute phase response to lipopolysaccharides Hahnefeld, L.; Kornstädt, L.; Kratz, D.; Ferreiros, N.; Geisslinger, G.; Pierre, S.; Scholich, K. | Journal Article |
2021 | Predicting the environmental emissions arising from conventional and nanotechnology-related pharmaceutical drug products Jung, F.; Thurn, M.; Krollik, K.; Gao, G.F.; Hering, I.; Eilebrecht, E.; Emara, Y.; Weiler, M.; Günday-Türeli, N.; Türeli, E.; Parnham, M.J.; Wacker, M.G. | Journal Article |
2021 | Production of baculovirus and stem cells for baculovirus-mediated gene transfer into human mesenchymal stem cells Eilts, F.; Harnischfeger, J.; Loewe, D.; Wolff, M.W.; Salzig, D.; Czermak, P. | Book Article |
2021 | The role of environmental specimen banks in monitoring environmental contamination Chaplow, Jacqueline S.; Bond, Alexander L.; Koschorreck, Jan; Rüdel, Heinz; Shore, Richard F. | Book Article |
2021 | Testing the bioaccumulation potential of manufactured nanomaterials in the freshwater amphipod Hyalella azteca Kühr, Sebastian; Kaegi, R.; Maletzki, D.; Schlechtriem, C. | Journal Article |
2021 | Toxicogenomic fin(ger)prints for thyroid disruption AOP refinement and biomarker identification in zebrafish embryos Reinwald, Hannes; König, Azora; Ayobahan, Steve U.; Alvincz, Julia; Sipos, Levente; Göckener, Bernd; Böhle, Gisela; Shomroni, Orr; Hollert, Henner; Salinas, Gabriela; Schäfers, Christoph; Eilebrecht, Elke; Eilebrecht, Sebastian | Journal Article |
2021 | Upstream and downstream processes for viral nanoplexes as vaccines Lothert, K.; Dekevic, G.; Loewe, D.; Salzig, D.; Czermak, P.; Wolff, M.W. | Book Article |
2020 | 12/15-Lipoxygenase choreographs the resolution of IgG-mediated skin inflammation Sezin, T.; Ferreiros, N.; Jennrich, M.; Ochirbold, K.; Seutter, M.; Attah, C.; Mousavi, S.; Zillikens, D.; Geisslinger, G.; Sadik, C.D. | Journal Article |
2020 | ABC transporter DerAB of lactobacillus casei mediates resistance against insect-derived defensins Revilla-Guarinos, A.; Zhang, Q.; Loderer, C.; Alcántara, C.; Müller, A.; Rahnamaeian, M.; Vilcinskas, A.; Gebhard, S.; Zúñiga, M.; Mascher, T. | Journal Article |
2020 | Agrocybe aegerita Serves as a Gateway for Identifying Sesquiterpene Biosynthetic Enzymes in Higher Fungi Zhang, C.; Chen, X.; Orban, A.; Shukal, S.; Birk, F.; Too, H.-P.; Rühl, M. | Journal Article |
2020 | Alox12/15 Deficiency Exacerbates, While Lipoxin A4 Ameliorates Hepatic Inflammation in Murine Alcoholic Hepatitis Queck, A.; Fink, A.F.; Sirait-Fischer, E.; Rüschenbaum, S.; Thomas, D.; Snodgrass, R.G.; Geisslinger, G.; Baba, H.A.; Trebicka, J.; Zeuzem, S.; Weigert, A.; Lange, C.M.; Brüne, B. | Journal Article |
2020 | Alternatives to Growth. Climax Economy Modelled on Ecology Schäfers, Christoph; Bette, Kristina; Herrmann, Florian; Nawroth, Georg | Book Article |
2020 | Analysis of potential risk factors of caprine coccidiosis Silva, L.M.R.; Carrau, T.; Vila-Viçosa, M.J.M.; Musella, V.; Rinaldi, L.; Failing, K.; Cortes, H.C.E.; Taubert, A.; Hermosilla, C. | Journal Article |
2020 | Angiotensin II treatment in COVID-19 patients: More risk than benefit? A single-center experience Heinicke, U.; Adam, E.; Sonntagbauer, M.; Knethen, A. von; Zacharowski, K.; Neb, H. | Journal Article |
2020 | Anthelminthic Activity of Assassin Bug Venom against the Blood Fluke Schistosoma mansoni Tonk, M.; Vilcinskas, A.; Grevelding, C.G.; Haeberlein, S. | Journal Article |
2020 | Antimicrobial peptides from rat-tailed maggots of the drone fly Eristalis tenax show potent activity against multidrug-resistant gram-negative bacteria Hirsch, R.; Wiesner, J.; Bauer, A.; Marker, A.; Vogel, H.; Hammann, P.E.; Vilcinskas, A. | Journal Article |
2020 | Application of General Unified Threshold Models of Survival Models for Regulatory Aquatic Pesticide Risk Assessment Illustrated with an Example for the Insecticide Chlorpyrifos Brock, T.; Arena, M.; Cedergreen, N.; Charles, S.; Duquesne, S.; Ippolito, A.; Klein, M.; Reed, M.; Teodorovic, I.; Brink, P.J. van den; Focks, A. | Journal Article |
2020 | Aquatic suspended particulate matter as source of eDNA for fish metabarcoding Diaz, Cecilia; Wege, Franziska-Frederike; Tang, Cuong Q.; Crampton‑Platt, Alexandra; Rüdel, Heinz; Eilebrecht, Elke; Koschorreck, Jan | Journal Article |
2020 | Aspergillus sydowii: Genome Analysis and Characterization of Two Heterologous Expressed, Non-redundant Xylanases Brandt, S.C.; Ellinger, B.; Nguyen, T. van; Harder, S.; Schlüter, H.; Hahnke, R.L.; Rühl, M.; Schäfer, W.; Gand, M. | Journal Article |
2020 | Assessment of SARS-CoV-2 Transmission on an International Flight and Among a Tourist Group Hoehl, S.; Karaca, O.; Kohmer, N.; Westhaus, S.; Graf, J.; Goetsch, U.; Ciesek, S. | Journal Article |
2020 | Attachment efficiency of nanomaterials to algae as an important criterion for ecotoxicity and grouping Hund-Rinke, K.; Sinram, T.; Schlich, K.; Nickel, C.; Dickehut, H.P.; Schmidt, M.; Kühnel, D. | Journal Article |
2020 | Author Correction: A new antibiotic selectively kills Gram-negative pathogens (Nature, 10.1038/s41586-019-1791-1) Imai, Y.; Meyer, K.J.; Iinishi, A.; Favre-Godal, Q.; Green, R.; Manuse, S.; Caboni, M.; Mori, M.; Niles, S.; Ghiglieri, M.; Honrao, C.; Ma, X.; Guo, J.J.; Makriyannis, A.; Linares-Otoya, L.; Böhringer, N.; Wuisan, Z.G.; Kaur, H.; Wu, R.; Mateus, A.; Typas, A.; Savitski, M.M.; Espinoza, J.L.; O’Rourke, A.; Nelson, K.E.; Hiller, S.; Noinaj, N.; Schäberle, T.F.; d'Onofrio, A.; Lewis, K. | Journal Article |
2020 | An automated and high-throughput-screening compatible pluripotent stem cell-based test platform for developmental and reproductive toxicity assessment of small molecule compounds Witt, Gesa; Keminer, Oliver; Leu, Jennifer; Tandon, Rashmi; Meiser, Ina; Willing, Anne; Winschel, Ingo; Abt, Jana-Christin; Brändl, Björn; Sébastien, Isabelle; Friese, Manuel A.; Müller, Franz Josef; Neubauer, Julia C.; Claussen, Carsten; Zimmermann, Heiko; Gribbon, Philip; Pless, Ole | Journal Article |
2020 | Bicistronic expression and differential localization of proteins in insect cells and Drosophila suzukii using picornaviral 2A peptides Schwirz, J.; Yan, Y.; Franta, Z.; Schetelig, M.F. | Journal Article |
2020 | Bildgebung bei der Psoriasisarthritis und Aspekte der röntgenologischen Progression Baraliakos, X.; Kleyer, A.; Simon, D.; Köhm, M.; Ohrndorf, S.; Sewerin, P. | Journal Article |
2020 | Bioavailability of silver from wastewater and planktonic food borne silver nanoparticles in the rainbow trout Oncorhynchus mykiss Zeumer, Richard; Hermsen, Lara; Kägi, Ralf; Kühr, Sebastian; Knopf, Burkhard; Schlechtriem, Christian | Journal Article |
2020 | Bioconcentration, metabolism and spatial distribution of 14C‐labelled laurate in the freshwater amphipod Hyalella Azteca Raths, Johannes; Kühr, Sebastian; Schlechtriem, Christian | Journal Article |
2020 | Biodegradation testing of volatile hydrophobic chemicals in water-sediment systems - Experimental developments and challenges Shresta, Prasit; Meisterjahn, Boris; Hughes, Christopher B.; Mayer, Philipp; Birch, Heidi; Hennecke, Dieter | Journal Article |
2020 | Biomagnification of ionizable organic compounds in rainbow trout Oncorhynchus mykiss Mueller, Carolin; Trapp, Stefan; Polesel, Fabio; Kuehr, Sebastian; Schlechtriem, Christian | Journal Article |
2020 | Biorelevant Two-Stage In Vitro Testing for rDCS Classification and in PBPK Modeling - Case Example Ritonavir Fiolka, T.; Abeele, J. Van Den; Augustijns, P.; Arora, S.; Dressman, J. | Journal Article |
2020 | Biotechnological Production of Odor-Active Methyl-Branched Aldehydes by a Novel α-Dioxygenase from Crocosphaera subtropica Hammer, A.K.; Albrecht, F.; Hahne, F.; Jordan, P.; Fraatz, M.A.; Ley, J.; Geissler, T.; Schrader, J.; Zorn, H.; Buchhaupt, M. | Journal Article |
2020 | Biotechnologically produced fucosylated oligosaccharides inhibit the binding of human noroviruses to their natural receptors Derya, S.M.; Spiegel, H.; Hanisch, F.-G.; Morozov, V.; Schroten, H.; Jennewein, S.; Parschat, K. | Journal Article |
2020 | Biotransformation Changes Bioaccumulation and Toxicity of Diclofenac in Aquatic Organisms Fu, Qiuguo; Fedrizzi, Davide; Kosfeld, Verena; Schlechtriem, Christian; Ganz, Vera; Derrer, Samuel; Rentsch, Daniel; Hollender, Juliane | Journal Article |
2020 | Biowaiver Monograph for Immediate-Release Solid Oral Dosage Forms: Moxifloxacin Hydrochloride Charoo, N.A.; Abdallah, D.B.; Parveen, T.; Abrahamsson, B.; Cristofoletti, R.; Groot, D.W.; Langguth, P.; Parr, A.; Polli, J.E.; Mehta, M.; Shah, V.P.; Tajiri, T.; Dressman, J. | Journal Article |
2020 | Biowaiver Monographs for Immediate Release Solid Oral Dosage Forms: Cephalexin Monohydrate Plöger, G.F.; Quizon, P.M.; Abrahamsson, B.; Cristofoletti, R.; Groot, D.W.; Parr, A.; Langguth, P.; Polli, J.E.; Shah, V.P.; Tajiri, T.; Mehta, M.U.; Dressman, J. | Journal Article |
2020 | Bone Marrow Mononuclear Cells Activate Angiogenesis via Gap Junction-Mediated Cell-Cell Interaction Kikuchi-Taura, A.; Okinaka, Y.; Takeuchi, Y.; Ogawa, Y.; Maeda, M.; Kataoka, Y.; Yasui, T.; Kimura, T.; Gul, S.; Claussen, C.; Boltze, J.; Taguchi, A. | Journal Article |
2020 | Branched-chain fatty acids as mediators of the activation of hepatic peroxisome proliferator-activated receptor alpha by a fungal lipid extract Maheshwari, G.; Ringseis, R.; Wen, G.; Gessner, D.K.; Rost, J.; Fraatz, M.A.; Zorn, H.; Eder, K. | Journal Article |
2020 | Brief clinical evaluation of six high-throughput SARS-CoV-2 IgG antibody assays Kohmer, N.; Westhaus, S.; Rühl, C.; Ciesek, S.; Rabenau, H.F. | Journal Article |
2020 | Canakinumab for Treatment of Adult-Onset Still's Disease to Achieve Reduction of Arthritic Manifestation (CONSIDER): Phase II, randomised, double-blind, placebo-controlled, multicentre, investigator-initiated trial Kedor, C.; Listing, J.; Zernicke, J.; Weiß, A.; Behrens, F.; Blank, N.; Henes, J.C.; Kekow, J.; Rubbert-Roth, A.; Schulze-Koops, H.; Seipelt, E.; Specker, C.; Feist, E. | Journal Article |
2020 | Cell-Type Targeted NF-kappaB Inhibition for the Treatment of Inflammatory Diseases Sehnert, B.; Burkhardt, H.; Dübel, S.; Voll, R.E. | Journal Article |
2020 | Central encoding of the strength of intranasal chemosensory trigeminal stimuli in a human experimental pain setting Lötsch, J.; Oertel, B.G.; Felden, L.; Nöth, U.; Deichmann, R.; Hummel, T.; Walter, C. | Journal Article |
2020 | Ceramide synthase 5 deficiency aggravates dextran sodium sulfate-induced colitis and colon carcinogenesis and impairs T-cell activation El-Hindi, K.; Brachtendorf, S.; Hartel, J.C.; Oertel, S.; Birod, K.; Trautmann, S.; Thomas, D.; Ulshöfer, T.; Weigert, A.; Utermöhlen, O.; Krönke, M.; Grösch, S. | Journal Article |
2020 | Characterization of the Nutritional Composition of a Biotechnologically Produced Oyster Mushroom and its Physiological Effects in Obese Zucker Rats Maheshwari, G.; Gessner, D.K.; Meyer, S.; Ahlborn, J.; Wen, G.; Ringseis, R.; Zorn, H.; Eder, K. | Journal Article |
2020 | Chemical starting matter for HNF4α ligand discovery and chemogenomics Meijer, I.; Willems, S.; Ni, X.; Heering, J.; Chaikuad, A.; Merk, D. | Journal Article |
2020 | Chemicals of emerging concern in marine specimens of the German Environmental Specimen Bank Fliedner, Annette; Rüdel, Heinz; Dreyer, Annekatrin; Pirntke, Ulrike; Koschorreck, Jan | Journal Article |
2020 | Chronic effects of wastewater-borne silver and titanium dioxide nanoparticles on the rainbow trout (Oncorhynchus mykiss) Zeumer, Richard; Galhano, Victor; Monteiro, Marta S.; Kühr, Sebastian; Knopf, Burkhard; Meisterjahn, Boris; Soares, Amadeu M.V.M.; Loureiro, Susana; Lopes, Isabel; Schlechtriem, Christian | Journal Article |
2020 | Collecting data through high throughput in vitro early toxicity and off-target liability assays to rapidly identify limitations of novel thyromimetics Runfola, M.; Sestito, S.; Gul, S.; Chiellini, G.; Rapposelli, S. | Journal Article |
2020 | Combinatorial metabolic engineering in saccharomyces cerevisiae for the enhanced production of the fpp-derived sesquiterpene germacrene Bröker, J.N.; Müller, B.; Prüfer, D.; Gronover, C.S. | Journal Article |
2020 | Combining biorelevant in vitro and in silico tools to investigate the in vivo performance of the amorphous solid dispersion formulation of etravirine in the fed state Litou, C.; Turner, D.B.; Holmstock, N.; Ceulemans, J.; Box, K.J.; Kostewicz, E.; Kuentz, M.; Holm, R.; Dressman, J. | Journal Article |
2020 | Comparative proteome and metabolome analyses of latex-exuding and non-exuding Taraxacum koksaghyz roots provide insights into laticifer biology Benninghaus, V.A.; Deenen, N. van; Müller, B.; Roelfs, K.-U.; Lassowskat, I.; Finkemeier, I.; Prüfer, D.; Schulze Gronover, C. | Journal Article |
2020 | Comparison of Alternative Methods for Bioaccumulation Assessment: Scope and Limitations of In Vitro Depletion Assays with Rainbow Trout and Bioconcentration Tests in the Freshwater Amphipod Hyalella azteca Kosfeld, Verena; Fu, Qiuguo; Ebersbach, Ina; Esser, Dana; Schauerte, Anna; Bischof, Ina; Hollender, Juliane; Schlechtriem, Christian | Journal Article |
2020 | Comprehensive analysis of all evolutionary paths between two divergent PDZ domain specificities Teyra, J.; Ernst, A.; Singer, A.; Sicheri, F.; Sidhu, S.S. | Journal Article |
2020 | Comprehensive evaluation of the metabolic effects of insect meal from Tenebrio molitor L. in growing pigs by transcriptomics, metabolomics and lipidomics Meyer, S.; Gessner, D.K.; Braune, M.S.; Friedhoff, T.; Most, E.; Höring, M.; Liebisch, G.; Zorn, H.; Eder, K.; Ringseis, R. | Journal Article |
2020 | Conformation-specific inhibitors of activated Ras GTPases reveal limited Ras dependency of patient-derived cancer organoids Wiechmann, S.; Maisonneuve, P.; Grebbin, B.M.; Hoffmeister, M.; Kaulich, M.; Clevers, H.; Rajalingam, K.; Kurinov, I.; Farin, H.F.; Sicheri, F.; Ernst, A. | Journal Article |
2020 | Correction to: Sustained improvement in work outcomes in employed patients with rheumatoid arthritis during 2 years of adalimumab therapy: An observational cohort study Behrens, F.; Tony, H.-P.; Koehm, M.; Schwaneck, E.C.; Gnann, H.; Greger, G.; Burkhardt, H.; Schmalzing, M. | Journal Article |
2020 | COVID-19-Related Coagulopathy - Is Transferrin a Missing Link? McLaughlin, K.-M.; Bechtel, M.; Bojkova, D.; Münch, C.; Ciesek, S.; Wass, M.N.; Michaelis, M.; Cinatl, J. | Journal Article |
2020 | CRISPR/Cas9 mediated disruption of the white gene leads to pigmentation deficiency and copulation failure in Drosophila suzukii Yan, Y.; Ziemek, J.; Schetelig, M.F. | Journal Article |
2020 | Current projection methods-induced biases at subgroup detection for machine-learning based data-analysis of biomedical data Lötsch, J.; Ultsch, A. | Journal Article |
2020 | A data science approach to the selection of most informative readouts of the human intradermal capsaicin pain model to assess pregabalin effects Lötsch, J.; Walter, C.; Zunftmeister, M.; Zinn, S.; Wolters, M.; Ferreiros, N.; Rossmanith, T.; Oertel, B.G.; Geisslinger, G. | Journal Article |
2020 | A data science-based analysis of seasonal patterns in outpatient presentations due to olfactory dysfunction Lötsch, J.; Hummel, T. | Journal Article |
2020 | Data-science-based subgroup analysis of persistent pain during 3 years after breast cancer surgery: A prospective cohort study Lötsch, J.; Ultsch, A.; Kalso, E. | Journal Article |
2020 | Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis Runfola, M.; Sestito, S.; Bellusci, L.; Pietra, V. la; D'Amore, V.M.; Kowalik, M.A.; Chiellini, G.; Gul, S.; Perra, A.; Columbano, A.; Marinelli, L.; Novellino, E.; Rapposelli, S. | Journal Article |
2020 | Design, Synthesis, and Structure - Activity Relationship Studies of Dual Inhibitors of Soluble Epoxide Hydrolase and 5-Lipoxygenase Hiesinger, K.; Kramer, J.S.; Beyer, S.; Eckes, T.; Brunst, S.; Flauaus, C.; Wittmann, S.K.; Weizel, L.; Kaiser, A.; Kretschmer, S.B.M.; George, S.; Angioni, C.; Heering, J.; Geisslinger, G.; Schubert-Zsilavecz, M.; Schmidtko, A.; Pogoryelov, D.; Pfeilschifter, J.; Hofmann, B.; Steinhilber, D.; Schwalm, S.; Proschak, E. | Journal Article |
2020 | Detection of biomarkers to differentiate endocrine disruption from hepatotoxicity in zebrafish (Danio rerio) using proteomics Ayobahan, Steve U.; Eilebrecht, Sebastian; Baumann, Lisa; Teigeler, Matthias; Hollert, Henner; Kalkhof, Stefan; Eilebrecht, Elke; Schäfers, Christoph | Journal Article |
2020 | Determination of low environmental free cyanide concentrations in freshwaters Knopf, Burkhard; Rüdel, Heinz; Hansknecht, Dirk; Klawonn, Thorsten; Kreuzer, Knut | Journal Article |
2020 | Development of a downstream process for the production of an inactivated whole hepatitis C virus vaccine Lothert, K.; Offersgaard, A.F.; Pihl, A.F.; Mathiesen, C.K.; Jensen, T.B.; Alzua, G.P.; Fahnøe, U.; Bukh, J.; Gottwein, J.M.; Wolff, M.W. | Journal Article |
2020 | Development of a method to determine the bioaccumulation of manufactured nanomaterials in filtering organisms (Bivalvia). Final Report Schlechtriem, Christian; Knopf, Burkhard; Kühr, Sebastian; Meisterjahn, Boris; Schröder, Nicola | Report |
2020 | Development of a solventless stir bar sorptive extraction/thermal desorption large volume injection capillary gas chromatographic-mass spectrometric method for ultra-trace determination of pyrethroids pesticides in river and tap water samples Sargazi, Mona; Bücking, Mark; Kaykhaii, Massoud | Journal Article |
2020 | Development of a test method for transformation of veterinary pharmaceuticals and biocides in anaerobic liquid manure Junker, Thomas; Atorf, Cornelia; Berkner, Silvia; Düring, Rolf-Alexander; Hennecke, Dieter; Herrchen, Monika; Konradi, Sabine; Merrettig‑Bruns, Ute; Römbke, Jörg; Wagner, Julia; Weinfurtner, Karlheinz | Journal Article |
2020 | Discovery of Protein-Protein Interaction Inhibitors by Integrating Protein Engineering and Chemical Screening Platforms Maculins, T.; Garcia-Pardo, J.; Skenderovic, A.; Gebel, J.; Putyrski, M.; Vorobyov, A.; Busse, P.; Varga, G.; Kuzikov, M.; Zaliani, A.; Rahighi, S.; Schaeffer, V.; Parnham, M.J.; Sidhu, S.S.; Ernst, A.; Dötsch, V.; Akutsu, M.; Dikic, I. | Journal Article |
2020 | Disrupting the LC3 Interaction Region (LIR) Binding of Selective Autophagy Receptors Sensitizes AML Cell Lines to Cytarabine Putyrski, M.; Vakhrusheva, O.; Bonn, F.; Guntur, S.; Vorobyov, A.; Brandts, C.; Dikic, I.; Ernst, A. | Journal Article |
2020 | Dissolution testing of modified release products with biorelevant media: An OrBiTo ring study using the USP apparatus III and IV Reppas, C.; Vrettos, N.-N.; Dressman, J.; Andreas, C.J.; Miyaji, Y.; Brown, J.; Etherson, K.; Hanley, S.; Karkossa, F.; Karlsson, E.; Klein, S.; Maier, G.-M.; McAllister, M.; Mistry, N.; Rosenblatt, K.; Schäfer, K.J.; Smith, K.L.; Tomaszewska, I.; Williams, J.; Winge, F.; Vertzoni, M. | Journal Article |
2020 | Distribution Optimization: An evolutionary algorithm to separate Gaussian mixtures Lerch, F.; Ultsch, A.; Lötsch, J. | Journal Article |
2020 | The disturbed iron phenotype of tumor cells and macrophages in renal cell carcinoma influences tumor growth Schnetz, M.; Meier, J.K.; Rehwald, C.; Mertens, C.; Urbschat, A.; Tomat, E.; Akam, E.A.; Baer, P.; Roos, F.C.; Brüne, B.; Jung, M. | Journal Article |
2020 | Does concomitant methotrexate confer clinical benefits in patients treated with prior biologic therapy? Schmalzing, M.; Behrens, F.; Schwaneck, E.C.; Koehm, M.; Greger, G.; Gnann, H.; Burkhardt, H.; Tony, H.-P. | Journal Article |
2020 | Does Light Color Temperature Influence Aspects of Oviposition by the Black Soldier Fly (Diptera: Stratiomyidae)? Klüber, P.; Bakonyi, D.; Zorn, H.; Rühl, M. | Journal Article |
2020 | Dual Farnesoid X Receptor/Soluble Epoxide Hydrolase Modulators Derived from Zafirlukast Schierle, S.; Helmstädter, M.; Schmidt, J.; Hartmann, M.; Horz, M.; Kaiser, A.; Weizel, L.; Heitel, P.; Proschak, A.; Hernandez-Olmos, V.; Proschak, E.; Merk, D. | Journal Article |
2020 | An economic dilemma between molecular weapon systems may explain an arachno-atypical venom in wasp spiders (Argiope bruennichi) Lüddecke, T.; von Reumont, B.M.; Förster, F.; Billion, A.; Timm, T.; Lochnit, G.; Vilcinskas, A.; Lemke, S. | Journal Article |
2020 | Ectopic bone formation and systemic bone loss in a transmembrane TNF-driven model of human spondyloarthritis Christodoulou-Vafeiadou, E.; Geka, C.; Ntari, L.; Kranidioti, K.; Argyropoulou, E.; Meier, F.; Armaka, M.; Mourouzis, I.; Pantos, C.; Rouchota, M.; Loudos, G.; Denis, M.C.; Karagianni, N.; Kollias, G. | Journal Article |
2020 | The endocannabinoid anandamide has an anti-inflammatory effect on CCL2 expression in vascular smooth muscle cells Pflüger-Müller, B.; Oo, J.A.; Heering, J.; Warwick, T.; Proschak, E.; Günther, S.; Looso, M.; Rezende, F.; Fork, C.; Geisslinger, G.; Thomas, D.; Gurke, R.; Steinhilber, D.; Schulz, M.; Leisegang, M.S.; Brandes, R.P. | Journal Article |
2020 | Environmental hazard testing of nanobiomaterials Amorim, M.J.B.; Fernández-Cruz, M.L.; Hund-Rinke, K.; Scott-Fordsmand, J.J. | Journal Article |
2020 | Epidemiological screening of captive salamanders reveals current absence of batrachochytrium salamandrivorans in private collections throughout the federal state of Hesse (Germany) Jung, L.; Dusek, J.; Lüddecke, T.; Schulz, V.; Maier-Sam, K.; Habich, L.; Mosebach, A.; Lierz, M.; Ziemek, H.-P. | Journal Article |
2020 | Establishing virtual bioequivalence and clinically relevant specifications using in vitro biorelevant dissolution testing and physiologically-based population pharmacokinetic modeling. Case example: Naproxen Loisios-Konstantinidis, I.; Cristofoletti, R.; Fotaki, N.; Turner, D.B.; Dressman, J. | Journal Article |
2020 | Establishment and Characterization of a Unilateral UV-Induced Photoreceptor Degeneration Model in the C57Bl/6J Mouse Meer, A.-M. van der; Berger, T.; Müller, F.; Foldenauer, A.C.; Johnen, S.; Walter, P. | Journal Article |
2020 | Ether lipid and sphingolipid expression patterns are estrogen receptor-dependently altered in breast cancer cells Hahnefeld, L.; Gruber, L.; Schömel, N.; Fischer, C.; Mattjus, P.; Gurke, R.; Beretta, M.; Ferreirós, N.; Geisslinger, G.; Wegner, M.-S. | Journal Article |
2020 | European medicinal leeches - New roles in modern medicine Lemke, S.; Vilcinskas, A. | Journal Article |
2020 | Evaluation of Differences in Dosage Form Performance of Generics Using BCS-Based Biowaiver Specifications and Biopharmaceutical Modeling Hofsäss, M.A.; Dressman, J. | Journal Article |
2020 | Evaluation of potential environmental toxicity of polymeric nanomaterials and surfactants Hering, Indra; Eilebrecht, Elke; Parnham, Michael J.; Günday-Türeli, Nazende; Türeli, Akif Emre; Weiler, Marc; Schäfers, Christoph; Fenske, Martina; Wacker, Matthias G. | Journal Article |
2020 | Evaluation of the risk for soil organisms under real conditions Toschki, Andreas; Hammers-Wirtz, Monika; Poßberg, Claudia; Ross-Nickoll, Martina; Schäffer, Andreas; Schmidt, Burkhard; Scholz Starke, Björn; Römbke, Jörg; Scheffzyk, Adam; Klein, Michael; Hommen, Udo | Report |
2020 | Evidence of SARS-CoV-2 Infection in Returning Travelers from Wuhan, China Ciesek, Sandra | Journal Article |
2020 | Exercise-Induced Changes in Bioactive Lipids Might Serve as Potential Predictors of Post-Exercise Hypotension. A Pilot Study in Healthy Volunteers Wolters, M.C.; Schmetzer, J.; Möser, C.V.; Hahnefeld, L.; Angioni, C.; Thomas, D.; Ferreirós, N.; Geisslinger, G.; Niederberger, E. | Journal Article |
2020 | Exploring CYP2J2: Lipid mediators, inhibitors and therapeutic implications Sisignano, M.; Steinhilber, D.; Parnham, M.J.; Geisslinger, G. | Journal Article |
2020 | Factors determining microbial colonization of liquid nitrogen storage tanks used for archiving biological samples Bajerski, F.; Bürger, A.; Glasmacher, B.; Keller, E.R.J.; Müller, K.; Mühldorfer, K.; Nagel, M.; Rüdel, H.; Müller, T.; Schenkel, J.; Overmann, J. | Journal Article |
2020 | Fate of acrylamide during coffee roasting and in vitro digestion assessed with carbon 14- and carbon 13-labeled materials Badoud, Flavia; Göckener, Bernd; Severin, Kevin; Ernest, Marion; Romero, Roman; Alzieu, Thibaut; Glabasnia, Arne; Hamel, Jonas; Bücking, Mark; Delatour, Thierry | Journal Article |
2020 | Fate of Chlorpropham during High-Temperature Processing of Potatoes Göckener, Bernd; Kotthoff, Matthias; Kling, Hans-Willi; Bücking, Mark | Journal Article |
2020 | A field study in support of the monitoring of priority substances in German freshwater fish: Derivation of fillet-to-whole fish conversion factors Rüdel, Heinz; Radermacher, Georg; Fliedner, Annette; Lohmann, Nina; Duffek, Anja | Journal Article |
2020 | First Structure-Activity Relationship Study of Potent BLT2 Agonists as Potential Wound-Healing Promoters Hernandez-Olmos, V.; Heering, J.; Planz, V.; Liu, T.; Kaps, A.; Rajkumar, R.; Gramzow, M.; Kaiser, A.; Schubert-Zsilavecz, M.; Parnham, M.J.; Windbergs, M.; Steinhilber, D.; Proschak, E. | Journal Article |
2020 | Flow cytometry-based system for screening of lignin peroxidase mutants with higher oxidative stability Ilić Đurđić, K.; Ece, S.; Ostafe, R.; Vogel, S.; Balaž, A.M.; Schillberg, S.; Fischer, R.; Prodanovic, R. | Journal Article |
2020 | Fraunhofer-Institut für Molekularbiologie und Angewandte Oekologie. Jahresbericht 2019 | Annual Report |
2020 | From cancer to immune-mediated diseases and tolerance induction: Lessons learned from immune oncology and classical anti-cancer treatment Klöß, Stephan; Dehmel, Susann; Braun, Armin; Parnham, Michael J.; Koehl, Ulrike; Schiffmann, Susanne | Journal Article |
2020 | Das frühe Erkennen postoperativen Nierenversagens nach offener thorakoabdomineller Aortenchirurgie: Eine multizentrische Observationsstudie (Nephrocheck™-TAAA-Trial) Gombert, A.; Oberhuber, A.; Greiner, A.; Eierhoff, T.; Heine, B.; Omran, S.; Frese, J.; Doukas, P.; Foldenauer, A.-C.; Jacobs, M.J. | Journal Article |
2020 | Frühe, zeitlich begrenzte intensive immunmodulatorische Therapie zum Erreichen einer Remission in Psoriasis Arthritis Köhm, M. | Journal Article |
2020 | Function of Cathepsin K in the Central Nervous System of Male Mice is Independent of its Role in the Thyroid Gland Dauth, S.; Rakov, H.; Sîrbulescu, R.F.; Ilieş, I.; Weber, J.; Batbajar Dugershaw, B.; Braun, D.; Rehders, M.; Wirth, E.K.; Führer, D.; Schweizer, U.; Brix, K. | Journal Article |
2020 | Functional Characterization of Knock-In Mice Expressing a 12/15-Lipoxygenating Alox5 Mutant Instead of the 5-Lipoxygenating Wild-Type Enzyme Marbach-Breitrück, E.; Kutzner, L.; Rothe, M.; Gurke, R.; Schreiber, Y.; Reddanna, P.; Schebb, N.-H.; Stehling, S.; Wieler, L.H.; Heydeck, D.; Kuhn, H. | Journal Article |
2020 | Functional characterization of the Drosophila suzukii pro-apoptotic genes reaper, head involution defective and grim Jaffri, S.A.; Yan, Y.; Schwirz, J.; Schetelig, M.F. | Journal Article |
2020 | The Fundamental Clustering and Projection Suite (FCPS) Ultsch, A.; Lötsch, J. | Journal Article |
2020 | Gene expression variability between randomly and targeted transgene integration events in tobacco suspension cell lines Kirchhoff, Janina; Schiermeyer, Andreas; Schneider, Katja; Fischer, Rainer; Ainley, W. Michael; Webb, Steven R.; Schinkel, Helga; Schillberg, Stefan | Journal Article |
2020 | Genetic variants in FBLIM1 gene do not contribute to SAPHO syndrome and chronic recurrent multifocal osteomyelitis in typical patient groups Assmann, G.; Köhm, M.; Schuster, V.; Behrens, F.; Mössner, R.; Magnolo, N.; Oji, V.; Burkhardt, H.; Hüffmeier, U. | Journal Article |
2020 | Global occurrence, chemical properties, and ecological impacts of e-wastes (IUPAC technical report) Purchase, Diane; Abbasi, Golnoush; Bisschop, Lieselot; Chatterjee, Debashish; Ekberg, Christian; Ermolin, Mikhail; Fedotov, Petr; Garelick, Hemda; Isimekhai, Khadijah; Kandile, Nadia G.; Lundström, Mari; Matharu, Avtar; Miller, Bradley W.; Pineda, Antonio; Popoola, Oluseun E.; Retegan, Teodora; Ruedel, Heinz; Serpe, Angela; Sheva, Yehuda; Surati, Kiran R.; Walsh, Fiona; Wilson, Benjamin P.; Wong, Ming Hung | Journal Article |
2020 | Glucagon-like peptide 1 levels predict cardiovascular risk in patients with acute myocardial infarction Kahles, F.; Rückbeil, M.V.; Mertens, R.W.; Foldenauer, A.C.; Arrivas, M.C.; Moellmann, J.; Lebherz, C.; Biener, M.; Giannitsis, E.; Katus, H.A.; Marx, N.; Lehrke, M. | Journal Article |
2020 | The gram-positive bacterium Leuconostoc pseudomesenteroides shows insecticidal activity against drosophilid and aphid pests Hiebert, N.; Kessel, T.; Skaljac, M.; Spohn, M.; Vilcinskas, A.; Lee, K.-Z. | Journal Article |
2020 | Growth Factor Receptor Signaling Inhibition Prevents SARS-CoV-2 Replication Klann, K.; Bojkova, D.; Tascher, G.; Ciesek, S.; Münch, C.; Cinatl, J. | Journal Article |
2020 | The gut and feed residue microbiota changing during the rearing of Hermetia illucens larvae Cifuentes, Y.; Glaeser, S.P.; Mvie, J.; Bartz, J.-O.; Müller, A.; Gutzeit, H.O.; Vilcinskas, A.; Kämpfer, P. | Journal Article |
2020 | Halogenation‐Guided Chemical Screening Provides Insight into Tjipanazole Biosynthesis by the Cyanobacterium Fischerella ambigua Chilczuk, T.; Schäberle, T.F.; Vahdati, S.; Mettal, U.; El Omari, M.; Enke, H.; Wiese, M.; König, G.M.; Niedermeyer, T.H.J. | Journal Article |
2020 | A head-to-head comparison of the efficacy and safety of ixekizumab and adalimumab in biological-naïve patients with active psoriatic arthritis: 24-week results of a randomised, open-label, blinded-assessor trial Mease, P.J.; Smolen, J.S.; Behrens, F.; Nash, P.; Liu Leage, S.; Li, L.; Tahir, H.; Gooderham, M.; Krishnan, E.; Liu-Seifert, H.; Emery, P.; Pillai, S.G.; Helliwell, P.S. | Journal Article |
2020 | High Glucosylceramides and Low Anandamide Contribute to Sensory Loss and Pain in Parkinson's Disease Klatt-Schreiner, K.; Valek, L.; Kang, J.-S.; Khlebtovsky, A.; Trautmann, S.; Hahnefeld, L.; Schreiber, Y.; Gurke, R.; Thomas, D.; Wilken-Schmitz, A.; Wicker, S.; Auburger, G.; Geisslinger, G.; Lötsch, J.; Pfeilschifter, W.; Djaldetti, R.; Tegeder, I. | Journal Article |
2020 | A high-throughput HIV-1 drug screening platform, based on lentiviral vectors and compatible with biosafety level-1 Ellinger, B.; Pohlmann, D.; Woens, J.; Jäkel, F.M.; Reinshagen, J.; Stocking, C.; Prassolov, V.S.; Fehse, B.; Riecken, K. | Journal Article |
2020 | Highlights of the 12th Wartburg Symposium on Flavor Chemistry & Biology Zorn, H.; Hofmann, T.; Dawid, C. | Journal Article |
2020 | Histone deacetylation inhibitors as modulators of regulatory T cells Knethen, A. von; Heinicke, U.; Weigert, A.; Zacharowski, K.; Brüne, B. | Journal Article |
2020 | Human biomonitoring of per- and polyfluoroalkyl substances in German blood plasma samples from 1982 to 2019 Göckener, Bernd; Weber, Till; Rüdel, Heinz; Bücking, Mark; Kolossa-Gehring, Marike | Journal Article |
2020 | Human iPSC-Derived Blood-Brain Barrier Models: Valuable Tools for Preclinical Drug Discovery and Development? Appelt-Menzel, Antje; Oerter, Sabrina; Mathew, Sanjana; Haferkamp, Undine; Hartmann, Carla; Jung, Matthias; Neuhaus, Winfried; Pless, Ole | Journal Article |
2020 | Human Mesenchymal Stromal Cells Are Resistant to SARS-CoV-2 Infection under Steady-State, Inflammatory Conditions and in the Presence of SARS-CoV-2-Infected Cells Schäfer, R.; Spohn, G.; Bechtel, M.; Bojkova, D.; Baer, P.C.; Kuci, S.; Seifried, E.; Ciesek, S.; Cinatl, J. | Journal Article |
2020 | Hypoxia inhibits ferritinophagy, increases mitochondrial ferritin, and protects from ferroptosis Fuhrmann, D.C.; Mondorf, A.; Beifuß, J.; Jung, M.; Brüne, B. | Journal Article |
2020 | Identification and molecular analysis of interaction sites in the MtSEO-F1 protein involved in forisome assembly Rose, J.; Visser, F.; Müller, B.; Senft, M.; Groscurth, S.; Sicking, K.F.; Twyman, R.M.; Prüfer, D.; Noll, G.A. | Journal Article |
2020 | Identification of a 2,4-diaminopyrimidine scaffold targeting Trypanosoma brucei pteridine reductase 1 from the LIBRA compound library screening campaign Linciano, P.; Cullia, G.; Borsari, C.; Santucci, M.; Ferrari, S.; Witt, G.; Gul, S.; Kuzikov, M.; Ellinger, B.; Santarem, N.; Cordeiro da Silva, A.; Conti, P.; Bolognesi, M.L.; Roberti, M.; Prati, F.; Bartoccini, F.; Retini, M.; Piersanti, G.; Cavalli, A.; Goldoni, L.; Bertozzi, S.M.; Bertozzi, F.; Brambilla, E.; Rizzo, V.; Piomelli, D.; Pinto, A.; Bandiera, T.; Costi, M.P. | Journal Article |
2020 | Identification of entomopathogenic bacteria associated with the invasive pest Drosophila suzukii in infested areas of Germany Hiebert, N.; Carrau, T.; Bartling, M.; Vilcinskas, A.; Lee, K.-Z. | Journal Article |
2020 | Identification, cloning, expression and functional interrogation of the biosynthetic pathway of the polychlorinated triphenyls ambigol A-C from Fischerella ambigua 108b Duell, E.R.; Milzarek, T.M.; El Omari, M.; Linares-Otoya, L.J.; Schäberle, T.F.; König, G.M.; Gulder, T.A.M. | Journal Article |
2020 | IL-36 family cytokines in protective versus destructive inflammation Han, Y.; Huard, A.; Mora, J.; da Silva, P.; Brüne, B.; Weigert, A. | Journal Article |
2020 | Immune Checkpoint Blockade Improves Chemotherapy in the PyMT Mammary Carcinoma Mouse Model Sirait-Fischer, E.; Olesch, C.; Fink, A.F.; Berkefeld, M.; Huard, A.; Schmid, T.; Takeda, K.; Brüne, B.; Weigert, A. | Journal Article |
2020 | Impact of hyperhomocysteinemia and different dietary interventions on cognitive performance in a knock-in mouse model for alzheimer's disease Nieraad, H.; de Bruin, N.; Arne, O.; Hofmann, M.C.J.; Schmidt, M.; Saito, T.; Saido, T.C.; Gurke, R.; Schmidt, D.; Till, U.; Parnham, M.J.; Geisslinger, G. | Journal Article |
2020 | Impact of simulated sunlight on the degradation of pendimethalin in surface water in a scale‑up experiment in accordance to OECD TG 309 Hennecke, Dieter; Hassink, Jan; Klein, Judith; Kruse, Mike | Journal Article |
2020 | Impact of wastewater-borne nanoparticles of silver and titanium dioxide on the swimming behaviour and biochemical markers of Daphnia magna: An integrated approach Galhano, Victor; Hartmann, Sarah; Monteiro, Marta S.; Zeumer, Richard; Mozhayeva, Darya; Steinhoff, Benedikt; Müller, Katharina; Prenzel, Kirsten; Kunze, Jan; Kuhnert, Klaus-Dieter; Schönherr, Holger; Engelhard, Carsten; Schlechtriem, Christian; Loureiro, Susana; Soares, Amadeu M.V.M.; Witte, Klaudia; Lopes, Isabel | Journal Article |
2020 | Implementation of lipidomics in clinical routine: Can fluoride/citrate blood sampling tubes improve preanalytical stability? Hahnefeld, L.; Gurke, R.; Thomas, D.; Schreiber, Y.; Schäfer, S.M.G.; Trautmann, S.; Snodgrass, I.F.; Kratz, D.; Geisslinger, G.; Ferreiros, N. | Journal Article |
2020 | Improved transgenic sexing strains for genetic control of the Australian sheep blow fly Lucilia cuprina using embryo-specific gene promoters Yan, Y.; Williamson, M.E.; Davis, R.J.; Andere, A.A.; Picard, C.J.; Scott, M.J. | Journal Article |
2020 | Improvement in oxidative stability of versatile peroxidase by flow cytometry-based high-throughput screening system Ilić Đurđić, K.; Ece, S.; Ostafe, R.; Vogel, S.; Schillberg, S.; Fischer, R.; Prodanović, R. | Journal Article |
2020 | Improvement of DNA Vector Delivery of DOTAP Lipoplexes by Short-Chain Aminolipids Buck, J.; Mueller, D.; Mettal, U.; Ackermann, M.; Grisch-Chan, H.M.; Thöny, B.; Zumbuehl, A.; Huwyler, J.; Witzigmann, D. | Journal Article |
2020 | In-vitro safety and off-target profile of the anti-parasitic arylmethylaminosteroid 1o Blum, L.; Gul, S.; Ulshöfer, T.; Henke, M.; Krieg, R.; Berneburg, I.; Thomas, D.; Trautmann, S.; Kurz, J.; Geyer, J.; Geisslinger, G.; Becker, K.; Parnham, M.J.; Schiffmann, S. | Journal Article |
2020 | Incretin combination therapy for the treatment of non-alcoholic steatohepatitis Kannt, A.; Madsen, A.N.; Kammermeier, C.; Elvert, R.; Klöckener, T.; Bossart, M.; Haack, T.; Evers, A.; Lorenz, K.; Hennerici, W.; Rocher, C.; Böcskei, Z.; Guillemot, J.-C.; Mikol, V.; Pattou, F.; Staels, B.; Wagner, M. | Journal Article |
2020 | Individual therapeutic DAS28-dcrit responses differentiate between effectiveness of rheumatoid arthritis therapies and reflect patient-reported outcomes Koehm, M.; McIntosh, M.J.; Hofmann, M.W.; Abraham, V.; Gabay, C.; Choy, E.H.; Kavanaugh, A.; Burkhardt, H.; Behrens, F. | Journal Article |
2020 | Industriebeispiele und Anwendungsbereiche Schwarz, Thomas; Gürtler, Christoph; Müller, Torsten; Mihalcea, Christophe; Burton, Freya; Conrado, Robert; Simpson, Sean; Maru, Biniam T; Munasinghe, Pradeep C; Jones, Shawn W.; Tracy, Bryan P.; Machielsen, Ronnie; Gordon, Ross; Pant, Deepak; Bulut, Metin; Wever, Helen de; Kensy, Frank; Verseck, Stefan; Janke, Christian | Book Article |
2020 | Influence of glycosphingolipids on cancer cell energy metabolism Schömel, N.; Geisslinger, G.; Wegner, M.-S. | Journal Article |
2020 | Influence of soil on the uptake of perfluoroalkyl acids by lettuce: A comparison between a hydroponic study and a field study Felizeter, S.; Jürling, H.; Kotthoff, M.; Voogt, P. de; McLachlan, M.S. | Journal Article |
2020 | Inhibition of histone acetylation and deacetylation enzymes affects longevity, development, and fecundity in the pea aphid (Acyrthosiphon pisum) Kirfel, P.; Skaljac, M.; Grotmann, J.; Kessel, T.; Seip, M.; Michaelis, K.; Vilcinskas, A. | Journal Article |
2020 | Innovative Imaging Technique for Visualization of Vascularization and Established Methods for Detection of Musculoskeletal Inflammation in Psoriasis Patients Köhm, M.; Zerweck, L.; Ngyuen, P.-H.; Burkhardt, H.; Behrens, F. | Journal Article |
2020 | Innovative Optical-Sensing Technology for the Online Fouling Characterization of Silicon Carbide Membranes during the Treatment of Oily Water Ebrahimi, M.; Schmidt, A.A.; Kaplan, C.; Schmitz, O.; Czermak, P. | Journal Article |
2020 | The insect antimicrobial peptide cecropin A disrupts uropathogenic Escherichia coli biofilms Kalsy, M.; Tonk, M.; Hardt, M.; Dobrindt, U.; Zdybicka-Barabas, A.; Cytrynska, M.; Vilcinskas, A.; Mukherjee, K. | Journal Article |
2020 | Insect Biotechnology. Insects as a Resource Vilcinskas, Andreas | Book Article |
2020 | Insektizide in Böden unterschiedlicher Bewirtschaftung Leisner, Jörg; Guhl, Barbara; Hindersmann, Benjamin; Göckener, Bernd | Journal Article |
2020 | Interfacing human induced pluripotent stem cell-derived neurons with designed nanowire arrays as a future platform for medical applications Harberts, J.; Haferkamp, U.; Haugg, S.; Fendler, C.; Lam, D.; Zierold, R.; Pless, O.; Blick, R.H. | Journal Article |
2020 | Interprofessionelle Versorgung von Patienten mit rheumatoider Arthritis aus hausärztlicher Sicht: Ergebnisse einer Querschnittserhebung Schneider, E.; Petersen, J.J.; Schulz-Rothe, S.; Gerlach, F.M.; Rossmanith, T.; Siebenhofer, A.; Mergenthal, K. | Journal Article |
2020 | Intravenous Bone Marrow Mononuclear Cells Transplantation in Aged Mice Increases Transcription of Glucose Transporter 1 and Na+/K+-ATPase at Hippocampus Followed by Restored Neurological Functions Takeuchi, Y.; Okinaka, Y.; Ogawa, Y.; Kikuchi-Taura, A.; Kataoka, Y.; Gul, S.; Claussen, C.; Boltze, J.; Taguchi, A. | Journal Article |
2020 | Investigation of Dissolution Performance of Hard Gelatin Capsule Products Using Various Sinkers Mansuroglu, Y.; Dressman, J. | Journal Article |
2020 | The iron load of lipocalin-2 (LCN-2) defines its pro-tumour function in clear-cell renal cell carcinoma Rehwald, C.; Schnetz, M.; Urbschat, A.; Mertens, C.; Meier, J.K.; Bauer, R.; Baer, P.; Winslow, S.; Roos, F.C.; Zwicker, K.; Huard, A.; Weigert, A.; Brüne, B.; Jung, M. | Journal Article |
2020 | l-Thyroxin and the Nonclassical Thyroid Hormone TETRAC are Potent Activators of PPARγ Gellrich, L.; Heitel, P.; Heering, J.; Kilu, W.; Pollinger, J.; Goebel, T.; Kahnt, A.; Arifi, S.; Pogoda, W.; Paulke, A.; Steinhilber, D.; Proschak, E.; Wurglics, M.; Schubert-Zsilavecz, M.; Chaikuad, A.; Knapp, S.; Bischoff, I.; Fürst, R.; Merk, D. | Journal Article |
2020 | Larvae of the clothing moth tineola bisselliella maintain gut bacteria that secrete enzyme cocktails to facilitate the digestion of keratin Vilcinskas, A.; Schwabe, M.; Brinkrolf, K.; Plarre, R.; Wielsch, N.; Vogel, H. | Journal Article |
2020 | LC-MS analysis of the degradation products of a sprayable, biodegradable poly(ester-urethane-urea) Borrowman, C.K.; Bücking, M.; Göckener, B.; Adhikari, R.; Saito, K.; Patti, A.F. | Journal Article |
2020 | Lead Optimization of Phthalazinone Phosphodiesterase Inhibitors as Novel Antitrypanosomal Compounds Salado, I.G.; Singh, A.K.; Moreno-Cinos, C.; Sakaine, G.; Siderius, M.; Veken, P. Van Der; Matheeussen, A.; Meer, T. Van Der; Sadek, P.; Gul, S.; Maes, L.; Sterk, G.-J.; Leurs, R.; Brown, D.; Augustyns, K. | Journal Article |
2020 | Lipid Mediator Profiles Predict Response to Therapy with an Oral Frankincense Extract in Relapsing-Remitting Multiple Sclerosis Stürner, K.H.; Werz, O.; Koeberle, A.; Otto, M.; Pless, O.; Leypoldt, F.; Paul, F.; Heesen, C. | Journal Article |
2020 | The Lipid Receptor G2A (GPR132) Mediates Macrophage Migration in Nerve Injury-Induced Neuropathic Pain Osthues, T.; Zimmer, B.; Rimola, V.; Klann, K.; Schilling, K.; Mathoor, P.; Angioni, C.; Weigert, A.; Geisslinger, G.; Münch, C.; Scholich, K.; Sisignano, M. | Journal Article |
2020 | Local fixation of antibiotics with fibrin spray on soft tissues: Experimental study on the relevance of the application techniques Verboket, R.; Marzi, I.; Fleck, S.C.; Frank, J.; Janko, M. | Journal Article |
2020 | Long-term stimulation of toll-like receptor-2 and -4 upregulates 5-LO and 15-LO-2 expression thereby inducing a lipid mediator shift in human monocyte-derived macrophages Ebert, R.; Cumbana, R.; Lehmann, C.; Kutzner, L.; Toewe, A.; Ferreirós, N.; Parnham, M.J.; Schebb, N.H.; Steinhilber, D.; Kahnt, A.S. | Journal Article |
2020 | Lymphocyte predominant cells detect Moraxella catarrhalis-derived antigens in nodular lymphocyte-predominant Hodgkin lymphoma Thurner, L.; Hartmann, S.; Fadle, N.; Regitz, E.; Kemele, M.; Kim, Y.-J.; Bohle, R.M.; Nimmesgern, A.; Müller, L. von; Kempf, V.A.J.; Weniger, M.A.; Neumann, F.; Schneider, N.; Vornanen, M.; Sundström, C.; Leval, L. de; Engert, A.; Eichenauer, D.A.; Küppers, R.; Preuss, K.-D.; Hansmann, M.-L.; Pfreundschuh, M. | Journal Article |
2020 | Lysine acetyltransferase p300/cbp plays an important role in reproduction, embryogenesis and longevity of the pea aphid acyrthosiphon pisum Kirfel, P.; Vilcinskas, A.; Skaljac, M. | Journal Article |
2020 | Machine-learned association of next-generation sequencing-derived variants in thermosensitive ion channels genes with human thermal pain sensitivity phenotypes Lötsch, J.; Kringel, D.; Geisslinger, G.; Oertel, B.G.; Resch, E.; Malkusch, S. | Journal Article |
2020 | Machine-learned identification of psychological subgroups with relation to pain interference in patients after breast cancer treatments Sipilä, R.; Kalso, E.; Lötsch, J. | Journal Article |
2020 | Machine-learning-based knowledge discovery in rheumatoid arthritis-related registry data to identify predictors of persistent pain Lötsch, J.; Alfredsson, L.; Lampa, J. | Journal Article |
2020 | Machine-learning-derived rules set excludes risk of Parkinson’s disease in patients with olfactory or gustatory symptoms with high accuracy Lötsch, J.; Haehner, A.; Hummel, T. | Journal Article |
2020 | Macrophage-derived iron-bound lipocalin-2 correlates with renal recovery markers following sepsis-induced kidney damage Mertens, C.; Kuchler, L.; Sola, A.; Guiteras, R.; Grein, S.; Brüne, B.; Knethen, A. von; Jung, M. | Journal Article |
2020 | The Major Floral Promoter NtFT5 in Tobacco (Nicotiana tabacum) is a Promising Target for Crop Improvement Schmidt, F.J.; Zimmermann, M.M.; Wiedmann, D.R.; Lichtenauer, S.; Grundmann, L.; Muth, J.; Twyman, R.M.; Prüfer, D.; Noll, G.A. | Journal Article |
2020 | Measuring pH and Buffer Capacity in Fluids Aspirated from the Fasted Upper Gastrointestinal Tract of Healthy Adults Litou, C.; Psachoulias, D.; Vertzoni, M.; Dressman, J.; Reppas, C. | Journal Article |
2020 | Membrane-based steric exclusion chromatography for the purification of a recombinant baculovirus and its application for cell therapy Lothert, K.; Sprick, G.; Beyer, F.; Lauria, G.; Czermak, P.; Wolff, M.W. | Journal Article |
2020 | MicroRNAs as emerging regulators of signaling in the tumor microenvironment Syed, S.N.; Brüne, B. | Journal Article |
2020 | MicroRNAs regulate innate immunity against uropathogenic and commensal-like Escherichia coli infections in the surrogate insect model Galleria mellonella Mukherjee, K.; Amsel, D.; Kalsy, M.; Billion, A.; Dobrindt, U.; Vilcinskas, A. | Journal Article |
2020 | Molecular farming - the slope of enlightenment Fischer, R.; Buyel, J.F. | Journal Article |
2020 | Molecular Networking-Guided Discovery and Characterization of Stechlisins, a Group of Cyclic Lipopeptides from a Pseudomonas sp. Marner, M.; Patras, M.A.; Kurz, M.; Zubeil, F.; Förster, F.; Schuler, S.; Bauer, A.; Hammann, P.; Vilcinskas, A.; Schaberle, T.F.; Glaeser, J. | Journal Article |
2020 | Natural antiviral compound silvestrol modulates human monocyte-derived macrophages and dendritic cells Blum, L.; Geisslinger, G.; Parnham, M.J.; Grünweller, A.; Schiffmann, S. | Journal Article |
2020 | Neuropathic and cAMP-induced pain behavior is ameliorated in mice lacking CNGB1 Kallenborn-Gerhardt, W.; Metzner, K.; Lu, R.; Petersen, J.; Kuth, M.S.; Heine, S.; Drees, O.; Paul, M.; Becirovic, E.; Kennel, L.; Flauaus, C.; Gross, T.; Wack, G.; Hohmann, S.W.; Nemirovski, D.; Del Turco, D.; Biel, M.; Geisslinger, G.; Michalakis, S.; Schmidtko, A. | Journal Article |
2020 | A new citrinin derivative from the Indonesian Marine Sponge-Associated Fungus Penicillium citrinum Sabdaningsih, A.; Liu, Y.; Mettal, U.; Heep, J.; Riyanti; Wang, L.; Cristianawati, O.; Nuryadi, H.; Sibero, M.T.; Marner, M.; Radjasa, O.K.; Sabdono, A.; Trianto, A.; Schäberle, T.F. | Journal Article |
2020 | Next-Generation Sequencing of T and B Cell Receptor Repertoires from COVID-19 Patients Showed Signatures Associated with Severity of Disease Schultheiß, C.; Paschold, L.; Simnica, D.; Mohme, M.; Willscher, E.; Wenserski, L. von; Scholz, R.; Wieters, I.; Dahlke, C.; Tolosa, E.; Sedding, D.G.; Ciesek, S.; Addo, M.; Binder, M. | Journal Article |
2020 | A non-parametric effect-size measure capturing changes in central tendency and data distribution shape Lötsch, J.; Ultsch, A. | Journal Article |
2020 | The NORMAN Association and the European Partnership for Chemicals Risk Assessment (PARC): Let’s cooperate! Dulio, V.; Koschorreck, J.; Bavel, B. van; Brink, P. van den; Hollender, J.; Munthe, J.; Schlabach, M.; Aalizadeh, R.; Agerstrand, M.; Ahrens, L.; Allan, I.; Alygizakis, N.; Barcelo, D.; Bohlin-Nizzetto, P.; Boutroup, S.; Brack, W.; Bressy, A.; Christensen, J.H.; Cirka, L.; Covaci, A.; Derksen, A.; Deviller, G.; Dingemans, M.M.L.; Engwall, M.; Fatta-Kassinos, D.; Gago-Ferrero, P.; Hernández, F.; Herzke, D.; Hilscherová, K.; Hollert, H.; Junghans, M.; Kasprzyk-Hordern, B.; Keiter, S.; Kools, S.A.E.; Kruve, A.; Lambropoulou, D.; Lamoree, M.; Leonards, P.; Lopez, B.; López de Alda, M.; Lundy, L.; Makovinská, J.; Marigómez, I.; Martin, J.W.; McHugh, B.; Miège, C.; O’Toole, S.; Perkola, N.; Polesello, S.; Posthuma, L.; Rodriguez-Mozaz, S.; Roessink, I.; Rostkowski, P.; Ruedel, H.; Samanipour, S.; Schulze, T.; Schymanski, E.L.; Sengl, M.; Tarábek, P.; Ten Hulscher, D.; Thomaidis, N.; Togola, A.; Valsecchi, S.; Leeuwen, S. van; Ohe, P. von der; Vorkamp, K.; Vrana, B.; Slobodnik, J. | Journal Article |
2020 | The omega-3 lipid 17,18-EEQ sensitizes TRPV1 and TRPA1 in sensory neurons through the prostacyclin receptor (IP) Schäfer, S.M.G.; Sendetski, M.; Angioni, C.; Nüsing, R.; Geisslinger, G.; Scholich, K.; Sisignano, M. | Journal Article |
2020 | Opportunities to debottleneck the downstream processing of the oncolytic measles virus Loewe, D.; Dieken, H.; Grein, T.A.; Weidner, T.; Salzig, D.; Czermak, P. | Journal Article |
2020 | Optimizing product quality in molecular farming Schiermeyer, Andreas | Journal Article |
2020 | The orphan nuclear receptor Nurr1 is responsive to non-steroidal anti-inflammatory drugs Willems, S.; Kilu, W.; Ni, X.; Chaikuad, A.; Knapp, S.; Heering, J.; Merk, D. | Journal Article |
2020 | Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity Shin, D.; Mukherjee, R.; Grewe, D.; Bojkova, D.; Baek, K.; Bhattacharya, A.; Schulz, L.; Widera, M.; Mehdipour, A.R.; Tascher, G.; Geurink, P.P.; Wilhelm, A.; Heden van Noort, G.J. van der; Ovaa, H.; Müller, S.; Knobeloch, K.-P.; Rajalingam, K.; Schulman, B.A.; Cinatl, J.; Hummer, G.; Ciesek, S.; Dikic, I. | Journal Article |
2020 | Parallel evolution of complex centipede venoms Jenner, R.; Reumont, B. von; Campbell, L.; Undheim, E. | Journal Article, Conference Paper |
2020 | Per- and polyfluoroalkyl substances in the German environment Kotthoff, M.; Fliedner, A.; Rüdel, H.; Göckener, B.; Bücking, M.; Biegel-Engler, A.; Koschorreck, J. | Journal Article |
2020 | Persistent, mobile and toxic substances in the environment: A spotlight on current research and regulatory activities Rüdel, Heinz; Körner, Wolfgang; Letzel, Thomas; Neumann, Michael; Nödler, Karsten; Reemtsma, Thorsten | Journal Article |
2020 | Photohormones Enable Optical Control of the Peroxisome Proliferator-Activated Receptor γ (PPARγ) Hinnah, K.; Willems, S.; Morstein, J.; Heering, J.; Hartrampf, F.W.W.; Broichhagen, J.; Leippe, P.; Merk, D.; Trauner, D. | Journal Article |
2020 | Phylotranscriptomic evidence for pervasive ancient hybridization among Old World salamanders Rancilhac, L.; Irisarri, I.; Angelini, C.; Arntzen, J.W.; Babik, W.; Bossuyt, F.; Künzel, S.; Lüddecke, T.; Pasmans, F.; Sanchez, E.; Weisrock, D.; Veith, M.; Wielstra, B.; Steinfartz, S.; Hofreiter, M.; Philippe, H.; Vences, M. | Journal Article |
2020 | Physiologically based pharmacokinetic model outputs depend on dissolution data and their input Klumpp, L.; Dressman, J. | Journal Article |
2020 | A physiologically-based nanocarrier biopharmaceutics model to reverse-engineer the in vivo drug release Nagpal, S.; Braner, S.; Modh, H.; Tan, A.X.X.; Mast, M.-P.; Chichakly, K.; Albrecht, V.; Wacker, M.G. | Journal Article |
2020 | Potential Applications of Plant Biotechnology against SARS-CoV-2 Capell, T.; Twyman, R.M.; Armario-Najera, V.; Ma, J.K.-C.; Schillberg, S.; Christou, P. | Journal Article |
2020 | Predicting human pharmacokinetics of liposomal temoporfin using a hybrid in silico model Jablonka, L.; Ashtikar, M.; Gao, G.F.; Thurn, M.; Modh, H.; Wang, J.-W.; Preuß, A.; Scheglmann, D.; Albrecht, V.; Röder, B.; Wacker, M.G. | Journal Article |
2020 | Production and purification of fructo-oligosaccharides using an enzyme membrane bioreactor and subsequent fermentation with probiotic Bacillus coagulans Fan, R.; Burghardt, J.P.; Prell, F.; Zorn, H.; Czermak, P. | Journal Article |
2020 | The production of isoprene from cellulose using recombinant Clostridium cellulolyticum strains expressing isoprene synthase Janke, C.; Gaida, S.; Jennewein, S. | Journal Article |
2020 | Progranulin deficiency confers resistance to autoimmune encephalomyelitis in mice Schmitz, K.; Wilken-Schmitz, A.; Vasic, V.; Brunkhorst, R.; Schmidt, M.; Tegeder, I. | Journal Article |
2020 | Proline-Rich Antimicrobial Peptides in Medicinal Maggots of Lucilia sericata Interact with Bacterial DnaK but do not Inhibit Protein Synthesis Cytrynska, M.; Rahnamaeian, M.; Zdybicka-Barabas, A.; Dobslaff, K.; Züchner, T.; Sacheau, G.; Innis, C.A.; Vilcinskas, A. | Journal Article |
2020 | Proteo-Transcriptomic Analysis Identifies Potential Novel Toxins Secreted by the Predatory, Prey-Piercing Ribbon Worm Amphiporus lactifloreus Reumont, B.M. von; Lüddecke, T.; Timm, T.; Lochnit, G.; Vilcinskas, A.; Döhren, J. von; Nilsson, M.A. | Journal Article |
2020 | Proteomics as an alternative approach for hazard characterization and the identification of specific chemical targets: Elucidation of potential biomarkers for differentiating endocrine disruption from hepatotoxicity Ayobahan, Steve Uwa : Hollert, Henner; Schäfers, Christoph; Schäffer, Andreas | Dissertation |
2020 | Quintaquinone, a Merosesquiterpene from the Yellow Sponge Verongula cf. rigida Esper Jiso, A.; Kittiwisut, S.; Chantakul, R.; Yuenyongsawad, S.; Putchakarn, S.; Schäberle, T.F.; Temkitthaworn, P.; Ingkaninan, K.; Chaithirayanon, K.; Plubrukarn, A. | Journal Article |
2020 | Rab27a Contributes to the Processing of Inflammatory Pain in Mice Gross, T.; Wack, G.; Syhr, K.M.J.; Tolmachova, T.; Seabra, M.C.; Geisslinger, G.; Niederberger, E.; Schmidtko, A.; Kallenborn-Gerhardt, W. | Journal Article |
2020 | The Radiokitchen: Understanding chemical reactions during food processing Bücking, Mark; Göckener, Bernd | Journal Article |
2020 | Random forests followed by computed ABC analysis as a feature selection method for machine learning in biomedical data Lötsch, J.; Ultsch, A. | Conference Paper |
2020 | Rare Loss-of-Function Mutation in SERPINA3 in Generalized Pustular Psoriasis Frey, S.; Sticht, H.; Wilsmann-Theis, D.; Gerschütz, A.; Wolf, K.; Löhr, S.; Haskamp, S.; Frey, B.; Hahn, M.; Ekici, A.B.; Uebe, S.; Thiel, C.; Reis, A.; Burkhardt, H.; Behrens, F.; Köhm, M.; Rech, J.; Schett, G.; Assmann, G.; Kingo, K.; Koks, S.; Mössner, R.; Prinz, J.C.; Oji, V.; Schulz, P.; Muñoz, L.E.; Kremer, A.E.; Wenzel, J.; Hüffmeier, U. | Journal Article |
2020 | Recent advances in Salamandra skin poison research Lüddecke, T. | Journal Article, Conference Paper |
2020 | Redox Regulation of PPARγ in Polarized Macrophages Trümper, V.; Wittig, I.; Heidler, J.; Richter, F.; Brüne, B.; Knethen, A. von | Journal Article |
2020 | Relevance of instruments for measurements of quality of life in the AMNOG context Schneider, N. | Book Article |
2020 | Removal of Small-Molecular Byproducts from Crude Fructo-Oligosaccharide Preparations by Fermentation Using the Endospore-Forming Probiotic Bacillus coagulans Fan, R.; Burghardt, J.P.; Xiong, T.; Czermak, P. | Journal Article |
2020 | Reprograming of epigenetic mechanisms controlling host insect immunity and development in response to egg-laying by a parasitoid wasp Özbek, R.; Mukherjee, K.; Uçkan, F.; Vilcinskas, A. | Journal Article |
2020 | Retraction notice to "Differentiation of human iPSCs into VSMCs and generation of VSMC-derived calcifying vascular cells" [Stem Cell Res. 31 (2018) 62-70] Trillhaase, A.; Haferkamp, U.; Rangnau, A.; Märtens, M.; Schmidt, B.; Trilck, M.; Seibler, P.; Aherrahrou, R.; Erdmann, J.; Aherrahrou, Z. | Journal Article |
2020 | Retrospective analysis of cyclic volatile methylsiloxanes in archived German fish samples covering a period of two decades Radermacher, Georg; Rüdel, Heinz; Wesch, Charlotte; Böhnhardt, Anna; Koschorreck, Jan | Journal Article |
2020 | Robot Cookies - Plant Cell Packs as an Automated High-Throughput Screening Platform Based on Transient Expression Gengenbach, B.B.; Opdensteinen, P.; Buyel, J.F. | Journal Article |
2020 | Robustheitsuntersuchung zur Resorptionsverfügbarkeit von Schadstoffen in Böden. Abschlussbericht Barkowski, Dietmar; Krüger, Gerald; Machtolf, Monika; Derz, Kerstin; Küchler, Frank | Report |
2020 | S1P d20:1, an endogenous modulator of S1P d18:1/S1P2-dependent signaling Vutukuri, R.; Koch, A.; Trautmann, S.; Schreiber, Y.; Thomas, D.; Mayser, F.; Meyer zu Heringdorf, D.; Pfeilschifter, J.; Pfeilschifter, W.; Brunkhorst, R. | Journal Article |
2020 | S1PR4 ablation reduces tumor growth and improves chemotherapy via CD8+ T cell expansion Olesch, C.; Sirait-Fischer, E.; Berkefeld, M.; Fink, A.F.; Susen, R.M.; Ritter, B.; Michels, B.E.; Steinhilber, D.; Greten, F.R.; Savai, R.; Takeda, K.; Brüne, B.; Weigert, A. | Journal Article |
2020 | S1PR4-dependent CCL2 production promotes macrophage recruitment in a murine psoriasis model Schuster, C.; Huard, A.; Sirait-Fischer, E.; Dillmann, C.; Brüne, B.; Weigert, A. | Journal Article |
2020 | Saturation mutagenesis to improve the degradation of azo dyes by versatile peroxidase and application in form of VP-coated yeast cell walls Ilić Đurđić, K.; Ostafe, R.; Đurđević Đelmaš, A.; Popović, N.; Schillberg, S.; Fischer, R.; Prodanovic, R. | Journal Article |
2020 | A scalable downstream process for the purification of the cell culture-derived Orf virus for human or veterinary applications Lothert, K.; Pagallies, F.; Eilts, F.; Sivanesapillai, A.; Hardt, M.; Moebus, A.; Feger, T.; Amann, R.; Wolff, M.W. | Journal Article |
2020 | Schmerzmodelle und klinische Schmerzforschung sind kein Widerspruch Lötsch, J.; Geisslinger, G.; Walter, C. | Journal Article |
2020 | Schulung von Medizinischen Fachangestellten bei hausärztlichen Forschungsprojekten. Wissensgewinn und Unterschiede zwischen einer Präsenzschulung und dem Selbststudium eines Schulungshandbuches Mergenthal, K.; Schulz-Rothe, S.; Siebenhofer, A.; Gerlach, F.M.; Rossmanith, T.; Petersen, J.J. | Journal Article |
2020 | Seasonal phenotype-specific expression of microRNAs during metamorphosis in the European map butterfly Araschnia levana Mukherjee, K.; Baudach, A.; Vogel, H.; Vilcinskas, A. | Journal Article |
2020 | Seasonal variability in metal and metalloid burdens of mussels: Using data from the German Environmental Specimen Bank to evaluate implications for long-term mussel monitoring programs Knopf, Burkhard; Fliedner, Annette; Radermacher, Georg; Rüdel, Heinz; Paulus, Martin; Pirntke, Ulrike; Koschorreck, Jan | Journal Article |
2020 | Secukinumab versus adalimumab for treatment of active psoriatic arthritis (EXCEED): A double-blind, parallel-group, randomised, active-controlled, phase 3b trial McInnes, I.B.; Behrens, F.; Mease, P.J.; Kavanaugh, A.; Ritchlin, C.; Nash, P.; Masmitja, J.G.; Goupille, P.; Korotaeva, T.; Gottlieb, A.B.; Martin, R.; Ding, K.; Pellet, P.; Mpofu, S.; Pricop, L. | Journal Article |
2020 | Selection and application of trophic magnification factors for priority substances to normalize freshwater fish monitoring data under the European Water Framework Directive: A case study Rüdel, Heinz; Kosfeld, Verena; Fliedner, Annette; Radermacher, Georg; Schlechtriem, Christian; Duffek, Anja; Rauert, Caren; Koschorreck, Jan | Journal Article |
2020 | Selection of chromatographic methods for the purification of cell culture-derived Orf virus for its application as a vaccine or viral vector Lothert, K.; Pagallies, F.; Feger, T.; Amann, R.; Wolff, M.W. | Journal Article |
2020 | A Selective Modulator of Peroxisome Proliferator-Activated Receptor γ with an Unprecedented Binding Mode Hanke, T.; Cheung, S.-Y.; Kilu, W.; Heering, J.; Ni, X.; Planz, V.; Schierle, S.; Faudone, G.; Friedrich, M.; Wanior, M.; Werz, O.; Windbergs, M.; Proschak, E.; Schubert-Zsilavecz, M.; Chaikuad, A.; Knapp, S.; Merk, D. | Journal Article |
2020 | Sensitive aflatoxin B1 detection using nanoparticle-based competitive magnetic immunodetection Pietschmann, J.; Spiegel, H.; Krause, H.-J.; Schillberg, S.; Schröper, F. | Journal Article |
2020 | A sensitive in vitro performance assay reveals the in vivo drug release mechanisms of long-acting medroxyprogesterone acetate microparticles Gao, G.F.; Thurn, M.; Wendt, B.; Parnham, M.J.; Wacker, M.G. | Journal Article |
2020 | Short-term variability of the human serum metabolome depending on nutritional and metabolic health status Agueusop, I.; Musholt, P.B.; Klaus, B.; Hightower, K.; Kannt, A. | Journal Article |
2020 | Silencing of the DNA methyltransferase 1 associated protein 1 (DMAP1) gene in the invasive ladybird Harmonia axyridis implies a role of the DNA methyltransferase 1-DMAP1 complex in female fecundity Gegner, J.; Gegner, T.; Vogel, H.; Vilcinskas, A. | Journal Article |
2020 | The Specific IKKε/TBK1 Inhibitor Amlexanox Suppresses Human Melanoma by the Inhibition of Autophagy, NF-κB and MAP Kinase Pathways Möller, M.; Wasel, J.; Schmetzer, J.; Weiß, U.; Meissner, M.; Schiffmann, S.; Weigert, A.; Möser, C.V.; Niederberger, E. | Journal Article |
2020 | Sphingosine kinases are involved in macrophage NLRP3 inflammasome transcriptional induction Syed, S.N.; Weigert, A.; Brüne, B. | Journal Article |
2020 | Suitability of the z-Factor for Dissolution Simulation of Solid Oral Dosage Forms Hofsäss, M.A.; Dressman, J. | Journal Article |
2020 | Supplementation of sulfur-containing amino acids or essential amino acids does not reverse the hepatic lipid-lowering effect of a protein-rich insect meal in obese zucker rats Meyer, S.; Schäfer, L.; Röhrig, J.; Maheshwari, G.; Most, E.; Zorn, H.; Ringseis, R.; Eder, K.; Gessner, D.K. | Journal Article |
2020 | Sustained improvement in work outcomes in employed patients with rheumatoid arthritis during 2 years of adalimumab therapy: An observational cohort study Behrens, F.; Tony, H.-P.; Koehm, M.; Schwaneck, E.C.; Gnann, H.; Greger, G.; Burkhardt, H.; Schmalzing, M. | Journal Article |
2020 | A systematic comparison of chloroplast genome assembly tools Freudenthal, J.A.; Pfaff, S.; Terhoeven, N.; Korte, A.; Ankenbrand, M.J.; Förster, F. | Journal Article |
2020 | Systematic Discovery of Short Linear Motifs Decodes Calcineurin Phosphatase Signaling Wigington, C.P.; Roy, J.; Damle, N.P.; Yadav, V.K.; Blikstad, C.; Resch, E.; Wong, C.J.; Mackay, D.R.; Wang, J.T.; Krystkowiak, I.; Bradburn, D.A.; Tsekitsidou, E.; Hong, S.H.; Kaderali, M.A.; Xu, S.-L.; Stearns, T.; Gingras, A.-C.; Ullman, K.S.; Ivarsson, Y.; Davey, N.E.; Cyert, M.S. | Journal Article |
2020 | Tenebrio molitor larvae meal affects the cecal microbiota of growing pigs Meyer, S.; Gessner, D.K.; Maheshwari, G.; Röhrig, J.; Friedhoff, T.; Most, E.; Zorn, H.; Ringseis, R.; Eder, K. | Journal Article |
2020 | Terpenoids from the Coral-Derived Fungus Trichoderma harzianum (XS-20090075) Induced by Chemical Epigenetic Manipulation Shi, T.; Shao, C.-L.; Liu, Y.; Zhao, D.-L.; Cao, F.; Fu, X.-M.; Yu, J.-Y.; Wu, J.-S.; Zhang, Z.-K.; Wang, C.-Y. | Journal Article |
2020 | Testing the bioaccumulation of manufactured nanomaterials in the freshwater bivalve Corbicula fluminea using a new test method Kühr, Sebastian; Meisterjahn, Boris; Schröder, Nicola; Knopf, Burkhard; Völker, Doris; Schwirn, Kathrin; Schlechtriem, Christian | Journal Article |
2020 | Therapie der Psoriasisarthritis Köhm, M.; Behrens, F. | Journal Article |
2020 | Therapiestrategien der Psoriasisarthritis Köhm, M.; Burkhardt, H.; Behrens, F. | Journal Article |
2020 | A tiered high-throughput screening approach for evaluation of estrogen and androgen receptor modulation by environmentally relevant bisphenol A substitutes Keminer, Oliver; Teigeler, Matthias; Kohler, Manfred; Wenzel, Andrea; Arning, Jürgen; Kaßner, Franziska; Windshügel, Björn; Eilebrecht, Elke | Journal Article |
2020 | TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells Bestle, D.; Heindl, M.R.; Limburg, H.; Van Lam van, T.; Pilgram, O.; Moulton, H.; Stein, D.A.; Hardes, K.; Eickmann, M.; Dolnik, O.; Rohde, C.; Klenk, H.-D.; Garten, W.; Steinmetzer, T.; Böttcher-Friebertshäuser, E. | Journal Article |
2020 | Tracing neglected venom systems: Prediction of the industrial potential by a multi-disciplinary data network Kirchhoff, K.N.; Vilcinskas, A.; Wilke, T. | Journal Article, Conference Paper |
2020 | Transfer of Per- and Polyfluoroalkyl Substances (PFAS) from Feed into the Eggs of Laying Hens. Pt.1: Analytical Results Including a Modified Total Oxidizable Precursor Assay Göckener, Bernd; Eichhorn, Maria; Lämmer, René; Kotthoff, Matthias; Kowalczyk, Janine; Numata, Jorge; Schafft, Helmut; Lahrssen-Wiederholt, Monika; Bücking, Mark | Journal Article |
2020 | Transfer of Per- and Polyfluoroalkyl Substances (PFAS) from Feed into the Eggs of Laying Hens. Pt.2: Toxicokinetic Results Including the Role of Precursors Kowalczyk, Janine; Göckener, Bernd; Eichhorn, Maria; Kotthoff, Matthias; Bücking, Mark; Schafft, Helmut; Lahrssen-Wiederholt, Monika; Numata, Jorge | Journal Article |
2020 | Translational tarantula phylogenomics: Evolution of theraphosid spiders and their defensive arsenal with implications for venom bioprospecting Lüddecke, T. | Journal Article, Conference Paper |
2020 | Turbidimetry and dielectric spectroscopy as process analytical technologies for mammalian and insect cell cultures Käßer, L.; Zitzmann, J.; Grein, T.; Weidner, T.; Salzig, D.; Czermak, P. | Book Article |
2020 | UGCG overexpression leads to increased glycolysis and increased oxidative phosphorylation of breast cancer cells Schömel, N.; Gruber, L.; Alexopoulos, S.J.; Trautmann, S.; Olzomer, E.M.; Byrne, F.L.; Hoehn, K.L.; Gurke, R.; Thomas, D.; Ferreiros, N.; Geisslinger, G.; Wegner, M.-S. | Journal Article |
2020 | Die Umweltprobenbank des Bundes - Umwelt- und Humanproben Weber, T.; Koschorrek, J.; Rüther, M.; Körner, A.; Knopf, B.; Kotthoff, M.; Rüdel, H.; Lermen, D.; Bartel-Steinbach, M.; Göen, T.; Paulus, M.; Klein, R.; Veith, M.; Kolossa-Gehring, M. | Journal Article |
2020 | Unraveling the Pharmacological Potential of Lichen Extracts in the Context of Cancer and Inflammation With a Broad Screening Approach Ingelfinger, R.; Henke, M.; Roser, L.; Ulshöfer, T.; Calchera, A.; Singh, G.; Parnham, M.J.; Geisslinger, G.; Fürst, R.; Schmitt, I.; Schiffmann, S. | Journal Article |
2020 | Unravelling the uptake pathway and accumulation of silver from manufactured silver nanoparticles in the freshwater amphipod Hyalella azteca using correlative microscopy Kühr, Sebastian; Klehm, Jessica; Stehr, Claudia; Menzel, Matthias; Schlechtriem, Christian | Journal Article |
2020 | Untersuchungen zur möglichen Freisetzung von Nanopartikeln bei der Ablagerung und bodenbezogenen Anwendung von mineralischen Abfällen. Abschlussbericht Oischinger, Jürgen; Meiller, Martin; Daschner, Robert; Hennecke, Dieter; Hund-Rinke, Kerstin; Meisterjahn, Boris; Schröder, Nicola | Report |
2020 | The use of PBPK/PD to establish clinically relevant dissolution specifications for zolpidem immediate release tablets Paraiso, R.L.M.; Rose, R.H.; Fotaki, N.; McAllister, M.; Dressman, J.B. | Journal Article |
2020 | The venom gland transcriptome of the wasp spider Argiope bruennichi Lüddecke, T.; Förster, F.; Billion, A.; Reumont, B.M. von; Vilcinskas, A.; Lemke, S. | Journal Article, Conference Paper |
2019 | 3D Printed Modular Immunofiltration Columns for Frequency Mixing-Based Multiplex Magnetic Immunodetection Achtsnicht, S.; Tödter, J.; Niehues, J.; Telöken, M.; Offenhäusser, A.; Krause, H.J.; Schröper, F. | Journal Article |
2019 | 4 Ds in health research - working together toward rapid precision medicine Niederberger, E.; Parnham, M.J.; Maas, J.; Geisslinger, G. | Journal Article |
2019 | 5-Amino-1-β-D-Ribofuranosyl-Imidazole-4-Carboxamide (AICAR) Reduces Peripheral Inflammation by Macrophage Phenotype Shift Martin, L.M.; Möller, M.; Weiss, U.; Russe, O.Q.; Scholich, K.; Pierre, S.; Geisslinger, G.; Niederberger, E. | Journal Article |
2019 | α-Amino Diphenyl Phosphonates as Novel Inhibitors of Escherichia coli ClpP Protease Moreno-Cinos, C.; Sassetti, E.; Salado, I.G.; Witt, G.; Benramdane, S.; Reinhardt, L.; Cruz, C.D.; Joossens, J.; Veken, P. Van der; Brötz-Oesterhe, H.; Tammela, P.; Winterhalter, M.; Gribbon, P.; Windshügel, B.; Augustyns, K. | Journal Article |
2019 | Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform Moraes, C.B.; Witt, G.; Kuzikov, M.; Ellinper, B.; Calogeropoulou, T.; Prousis, K.C.; Mangani, S.; Pisa, F. di; Landi, G.; Dello Lacono, L.; Pozzi, C.; Freitas, L.H.; Pascoalino, B.D.; Bertolacini, C.P.; Behrens, B.; Keminer, O.; Leu, J.; Wolf, M.; Reinshagen, J.; Cordeiro-da-Silva, A.; Santarem, N.; Venturelli, A.; Wrigley, S.; Karunakaran, D.; Kebede, B.; Pohner, I.; Muller, W.; Panecka-Hofman, J.; Wade, R.C.; Fenske, M.; Clos, J.; Alunda, J.M.; Corral, M.J.; Uliassi, E.; Bolognesi, M.L.; Linciano, P.; Quotadamo, A.; Ferrari, S.; Santucci, M.; Borsari, C.; Costi, M.P.; Gul, S. | Journal Article |
2019 | Achievement Of CDAPSA Low Disease Activity Or Remission Is Associated With Control Of Articular And Extra-Articular Manifestations Of Active Psoriatic Arthritis In Subjects Treated With Apremilast Coates, L.C.; Mease, P.J.; Behrens, F.; Orbai, A.M.; Ogdie, A.; Brunori, M.; Teng, L.; Guerette, B.; Smolen, J.S. | Abstract |
2019 | Activated Cross-linked Agarose for the Rapid Development of Affinity Chromatography Resins - Antibody Capture as a Case Study Knödler, M.; Rühl, C.; Opdensteinen, P.; Buyel, J.F. | Journal Article |
2019 | Activation of Caspase-6 Is Promoted by a Mutant Huntingtin Fragment and Blocked by an Allosteric Inhibitor Compound Ehrnhoefer, D.E.; Skotte, N.H.; Reinshagen, J.; Qiu, X.; Windshügel, B.; Jaishankar, P.; Ladha, S.; Petina, O.; Khankischpur, M.; Nguyen, Y.T.N.; Caron, N.S.; Razeto, A.; Meyer zu Rheda, M.; Deng, Y.; Huynh, K.T.; Wittig, I.; Gribbon, P.; Renslo, A.R.; Geffken, D.; Gul, S.; Hayden, M.R. | Journal Article |
2019 | ADAM15 in Apoptosis Resistance of Synovial Fibroblasts Janczi, T.; Böhm, B.B.; Fehrl, Y.; DeGiacomo, P.; Kinne, R.W.; Burkhardt, H. | Journal Article |
2019 | Addition or removal of concomitant methotrexate alters adalimumab effectiveness in rheumatoid arthritis but not psoriatic arthritis Behrens, F.; Koehm, M.; Schwaneck, E.C.; Schmalzing, M.; Wittig, B.M.; Gnann, H.; Greger, G.; Tony, H.P.; Burkhardt, H. | Journal Article |
2019 | Advanced in silico modeling explains pharmacokinetics and biodistribution of temoporfin nanocrystals in humans Jablonka, L.; Ashtikar, M.; Gao, G.; Jung, F.; Thurn, M.; Preuß, A.; Scheglmann, D.; Albrecht, V.; Röder, B.; Wacker, M.G. | Journal Article |
2019 | Aeration and Shear Stress Are Critical Process Parameters for the Production of Oncolytic Measles Virus Grein, T.A.; Loewe, D.; Dieken, H.; Weidner, T.; Salzig, D.; Czermak, P. | Journal Article |
2019 | Aktuelle Therapie der Psoriasisarthritis Köhm, M.; Behrens, F. | Journal Article |
2019 | Alternativen zum Wachstum Schäfers, Christoph; Bette, Kristina; Herrmann, Florian; Nawroth, Georg | Book Article |
2019 | Analyses of association of psoriatic arthritis and psoriasis vulgaris with functional NCF1 variants Löhr, S.; Ekici, A.B.; Uebe, S.; Büttner, C.; Köhm, M.; Behrens, F.; Böhm, B.; Sticherling, M.; Schett, G.; Simon, D.; Mössner, R.; Nimeh, A.; Oji, V.; Assmann, G.; Rech, J.; Holmdahl, R.; Burkhardt, H.; Reis, A.; Hüffmeier, U. | Journal Article |
2019 | Antibacterial and antifungal activity of defensins from the Australian paralysis tick, Ixodes holocyclus Cabezas-Cruz, A.; Tonk, M.; Bleackley, M.R.; Valdes, J.J.; Barrero, R.A.; Hernández-Jarguín, A.; Moutailler, S.; Vilcinskas, A.; Richard-Forget, F.; Anderson, M.A.; Rodriguez-Valle, M. | Journal Article |
2019 | Antibiotic-producing beneficial bacteria in the gut of the burying beetle nicrophorus vespilloides Heise, P.; Liu, Y.; Degenkolb, T.; Vogel, H.; Schäberle, T.F.; Vilcinskas, A. | Journal Article |
2019 | The Antisteatotic and Hypolipidemic Effect of Insect Meal in Obese Zucker Rats is Accompanied by Profound Changes in Hepatic Phospholipid and 1-Carbon Metabolism Meyer, S.; Gessner, D.K.; Wen, G.; Most, E.; Liebisch, G.; Zorn, H.; Ringseis, R.; Eder, K. | Journal Article |
2019 | Application of a Refined Developability Classification System Rosenberger, J.; Butler, J.; Muenster, U.; Dressman, J. | Journal Article |
2019 | Application of adverse outcome pathways and quantitative in vitro-in vivo extrapolation (QIVIVE) modelling for risk assessment based on in vitro data Mally, A.; Birk, B.; Fiore, S. di; Ellinger, B.; Jarzina, S.; Reiser, P.; Taverne, F.; Kramer, N. | Abstract |
2019 | Application of the relationship between pharmacokinetics and pharmacodynamics in drug development and therapeutic equivalence: a PEARRL review Loisios‐Konstantinidis, I.; Paraiso, R.L.M.; Fotaki, N.; McAllister, M.; Cristofoletti, R.; Dressman, J. | Journal Article |
2019 | Association analyses of functional NCF1 variants in psoriatic arthritis and psoriasis vulgaris Hüffmeier, U.D.; Löhr, S.; Ekici, A.B.; Uebe, S.; Köhm, M.; Behrens, F.; Böhm, B.; Sticherling, M.; Schett, G.; Mössner, R.; Nimeh, A.; Assmann, G.; Rech, J.; Oji, V.; Holmdahl, R.; Burkhardt, H.; Reis, A. | Abstract |
2019 | Bewertung des endokrinen Potenzials von Bisphenol Alternativstoffen in umweltrelevanten Verwendungen. Abschlussbericht Eilebrecht, Elke; Wenzel, Andrea; Teigeler, Matthias; Windshügel, Björn; Keminer, Oliver; Chachulski, Laura; Kohler, Manfred | Report |
2019 | Beyond leukotriene formation Häfner, A.-K.; Kahnt, A.S.; Steinhilber, D. | Journal Article |
2019 | Biglycan evokes autophagy in macrophages via a novel CD44/Toll-like receptor 4 signaling axis in ischemia/reperfusion injury Poluzzi, C.; Nastase, M.-V.; Zeng-Brouwers, J.; Roedig, H.; Tzung-Harn Hsieh, L.; Michaelis, J.B.; Buhl, E.M.; Rezende, F.; Manavski, Y.; Bleich, A.; Boor, P.; Brandes, R.P.; Pfeilschifter, J.; Stelzer, E.H.K.; Münch, C.; Dikic, I.; Brandts, C.; Iozzo, R.V.; Wygrecka, M.; Schäfer, L. | Journal Article |
2019 | Bioconcentration studies with the freshwater amphipod Hyalella azteca: Are the results predictive of bioconcentration in fish? Schlechtriem, Christian; Kampe, Sebastian; Bruckert, Hans-Jörg; Bischof, Ina; Ebersbach, Ina; Kosfeld, Verena; Kotthoff, Matthias; Schäfers, Christoph; L’Haridon, Jacques | Journal Article |
2019 | Biodegradation of Volatile Chemicals in Soil: Separating Volatilization and Degradation in an Improved Test Setup (OECD 307) Shrestha, Prasit; Meisterjahn, Boris; Klein, Michael; Mayer, Philipp; Birch, Heidi; Hughes, Christopher B.; Hennecke, Dieter | Journal Article |
2019 | Biodegradation testing of hydrophobic and volatile organic chemicals Shrestha, Prasit : Hennecke, Dieter; Mayer, Philipp | Dissertation |
2019 | Biorelevant dissolution testing of a weak base: Interlaboratory reproducibility and investigation of parameters controlling in vitro precipitation Berben, P.; Ashworth, L.; Beato, S.; Bevernage, J.; Bruel, J.-L.; Butler, J.; Dressman, J.; Schäfer, K.; Hutchins, P.; Klumpp, L.; Mann, J.; Nicolai, J.; Ojala, K.; Patel, S.; Powell, S.; Rosenblatt, K.; Tomaszewska, I.; Williams, J.; Augustijns, P. | Journal Article |
2019 | Biosynthesis of Stereoisomers of Dill Ether and Wine Lactone by Pleurotus sapidus Trapp, T.; Kirchner, T.; Birk, F.; Fraatz, M.A.; Zorn, H. | Journal Article |
2019 | Biosynthetic Basis for Structural Diversity of Aminophenylpyrrole-Derived Alkaloids Linares-Otoya, L.; Liu, Y.; Linares-Otoya, V.; Armas-Mantilla, L.; Crüsemann, M.; Ganoza-Yupanqui, M.L.; Campos-Florian, J.; König, G.M.; Schäberle, T.F. | Journal Article |
2019 | Calculation of drug-polymer mixing enthalpy as a new screening method of precipitation inhibitors for supersaturating pharmaceutical formulations Price, D.J.; Nair, A.; Kuentz, M.; Dressman, J.; Saal, C. | Journal Article |
2019 | Canakinumab For The Treatment Of Adult Onset Still's Disease To Achieve Reduction Of Arthritic Manifestation At Week 12: An Investigator-Initiated Multi-Centre, Placebo-Controlled Study (Consider) Kedor, C.; Listing, J.; Zernicke, J.; Weiss, A.; Behrens, F.; Blank, N.; Henes, J.; Kekow, J.; Rubbert-Roth, A.; Schulze-Koops, H.; Seipelt, E.; Specker, C.; Feist, E. | Abstract |
2019 | Cancer-induced inflammation and inflammation-induced cancer in colon: A role for S1P lyase Schwiebs, A.; Herrero San Juan, M.; Schmidt, K.G.; Wiercinska, E.; Anlauf, M.; Ottenlinger, F.; Thomas, D.; Elwakeel, E.; Weigert, A.; Farin, H.F.; Bonig, H.; Scholich, K.; Geisslinger, G.; Pfeilschifter, J.M.; Radeke, H.H. | Journal Article |
2019 | Capillary electrophoresis‐based enzyme assays for β‐lactamase enzymes Chen, C.; Kramer, J.S.; Brunst, S.; Proschak, E.; Scriba, G.K.E. | Journal Article |
2019 | Carboxylic acid consumption and production by Corynebacterium glutamicum Conrady, M.; Lemoine, A.; Limberg, M.H.; Oldiges, M.; Neubauer, P.; Junne, S. | Journal Article |
2019 | Ceramides as Novel Disease Biomarkers Kurz, J.; Parnham, M.J.; Geisslinger, G.; Schiffmann, S. | Journal Article |
2019 | Certainties and uncertainties in accessing toxicity of non‑extractable residues (NER) in soil Harmsen, Joop; Hennecke, Dieter; Hund-Rinke, Kerstin; Lahr, Joost; Deneer, John | Journal Article |
2019 | Characterization Of Patients With Inflammatory Bowel Disease In The Ankylosing Spondylitis Cohort Prior And During Adalimumab Treatment: Data From A Large German Non-Interventional Study Köhm, M.; Schmalzing, M.; Schwaneck, E.C.; Gnann, H.; Tony, H.P.; Greger, G.; Boas, A.; Burkhardt, H.; Behrens, F. | Abstract |
2019 | Chronic Hypoxia Enhances β-Oxidation-Dependent Electron Transport via Electron Transferring Flavoproteins Fuhrmann, D.C.; Olesch, C.; Kurrle, N.; Schnütgen, F.; Zukunft, S.; Fleming, I.; Brüne, B. | Journal Article |
2019 | Circular synthesized CRISPR/Cas gRNAs for functional interrogations in the coding and noncoding genome Wegner, M.; Diehl, V.; Bittl, V.; Bruyn, R. de; Wiechmann, S.; Matthess, Y.; Heber, M.; Hayes, M.G.B.; Schaubeck, S.; Benner, C.; Heinz, S.; Bremm, A.; Dikic, I.; Ernst, A.; Kaulich, M. | Journal Article |
2019 | Clinical Usefulness of Self-Rated Olfactory Performance - A Data Science-Based Assessment of 6000 Patients Lötsch, J.; Hummel, T. | Journal Article |
2019 | Closing gaps for environmental risk screening of engineered nanomaterials Kühnel, D.; Nickel, C.; Hellack, B.; Zalm, E. van der; Kussatz, C.; Herrchen, M.; Meisterjahn, B.; Hund-Rinke, K. | Journal Article |
2019 | Clot derived contaminants in transplanted cells enhance inflammation at peri-stroke area after bone marrow mononuclear cell transplantation in murine stroke model Taura, A.; Ogawa, Y.; Okinaka, Y.; Takeuchi, Y.; Boltze, J.; Gul, S.; Claussen, C.; Taguchi, A. | Abstract |
2019 | Clot-Derived Contaminants in Transplanted Bone Marrow Mononuclear Cells Impair the Therapeutic Effect in Stroke Okinaka, Y.; Kikuchi-Taura, A.; Takeuchi, Y.; Ogawa, Y.; Boltze, J.; Gul, S.; Claussen, C.; Taguchi, A. | Journal Article |
2019 | Co-cultivation: A powerful tool for insulin-producing beta cell manufacturing Petry, F.; Czermak, P.; Salzig, D. | Abstract |
2019 | Combination of membrane-based and chromatographic methods to achieve pure and concentrated oncolytic measles viruses Loewe, D.; Dieken, H.; Grein, T.; Salzig, D.; Czermak, P. | Abstract |
2019 | A combined FSTRA-shotgun proteomics approach to identify molecular changes in zebrafish upon chemical exposure Ayobahan, S.U.; Eilebrecht, E.; Kotthoff, M.; Baumann, L.; Eilebrecht, S.; Teigeler, M.; Hollert, H.; Kalkhof, S.; Schäfers, C. | Journal Article |
2019 | A Combined Ultrafiltration/Diafiltration Step Facilitates the Purification of Cyanovirin-N From Transgenic Tobacco Extracts Opdensteinen, P.; Clodt, J.I.; Müschen, C.R.; Filiz, V.; Buyel, J.F. | Journal Article |
2019 | Combining biorelevant in vitro and in silico tools to simulate and better understand the in vivo performance of a nano-sized formulation of aprepitant in the fasted and fed states Litou, C.; Patel, N.; Turner, D.B.; Kostewicz, E.; Kuentz, M.; Box, K.J.; Dressman, J. | Journal Article |
2019 | Comparative estrogenicity of endogenous, environmental and dietary estrogens in pregnant women II Pande, P.; Fleck, S.C.; Twaddle, N.C.; Churchwell, M.I.; Doerge, D.R.; Teeguarden, J.G. | Journal Article |
2019 | Comparative multi-generation study on long-term effects of pristine and wastewater-borne silver and titanium dioxide nanoparticles on key lifecycle parameters in Daphnia magna Hartmann, S.; Louch, R.; Zeumer, R.; Steinhoff, B.; Mozhayeva, D.; Engelhard, C.; Schönherr, H.; Schlechtriem, C.; Witte, K. | Journal Article |
2019 | Comparison of different methodologies for selecting PELMO input parameters for groundwater modelling of plant protection products including current EU guidance (SANC0/12117/2014 - final, 2014) Klein, Michael | Report |
2019 | A comparison of log Kow (n‑octanol-water partition coefficient) values for non‑ionic, anionic, cationic and amphoteric surfactants determined using predictions and experimental methods Hodges, Geoff; Eadsforth, Charles; Bossuyt, Bart; Bouvy, Alain; Enrici, Marie‑Helene; Geurts, Marc; Kotthoff, Matthias; Michie, Eleanor; Miller, Dennis; Müller, Josef; Oetter, Gunter; Roberts, Jayne; Schowanek, Diederik; Sun, Ping; Venzmer, Joachim | Journal Article |
2019 | Comparison of microbial and transient expression (tobacco plants and plant-cell packs) for the production and purification of the anticancer mistletoe lectin viscumin Gengenbach, B.B.; Keil, L.L.; Opdensteinen, P.; Müschen, C.R.; Melmer, G.; Lentzen, H.; Bührmann, J.; Buyel, J.F. | Journal Article |
2019 | Comparison of the environmental properties of parasiticides and harmonisation of the basis for environmental assessment at the EU level Römbke, Jörg; Duis, Karen; Egeler, Philipp; Gilberg, Daniel; Schuh, Christine; Herrchen, Monika; Hennecke, Dieter; Hölzle, Ludwig E.; Heilmann-Thudium, Brigitte; Wohde, Manuel; Wagner, Julia; Düring, Rolf-Alexander | Report |
2019 | Complete genome sequence of the corallopyronin a-producing myxobacterium corallococcus coralloides B035 Bouhired, S.; Rupp, O.; Blom, J.; Schäberle, T.F.; Schiefer, A.; Kehraus, S.; Pfarr, K.; Goesmann, A.; Hoerauf, A.; König, G. | Journal Article |
2019 | The complete mitochondrial genome of the hymenopteran hunting robber fly Dasypogon diadema Drukewitz, S.H.; Jauss, R.-T.; Bokelmann, L.; Reumont, B.M. von | Journal Article |
2019 | Computational functional genomics-based reduction of disease-related gene sets to their key components Lippmann, C.; Ultsch, A.; Lötsch, J. | Journal Article |
2019 | Computer-Aided Selective Optimization of Side Activities of Talinolol Hiesinger, K.; Kramer, J.S.; Achenbach, J.; Moser, D.; Weber, J.; Wittmann, S.K.; Morisseau, C.; Angioni, C.; Geisslinger, G.; Kahnt, A.S.; Kaiser, A.; Proschak, A.; Steinhilber, D.; Pogoryelov, D.; Wagner, K.; Hammock, B.D.; Proschak, E. | Journal Article |
2019 | Computer-Assisted Discovery and Structural Optimization of a Novel Retinoid X Receptor Agonist Chemotype Heitel, P.; Gellrich, L.; Kalinowsky, L.; Heering, J.; Kaiser, A.; Ohrndorf, J.; Proschak, E.; Merk, D. | Journal Article |
2019 | The conspicuous postmetamorphic coloration of fire salamanders, but not their toxicity, is affected by larval background albedo Sanchez, E.; Pröhl, H.; Lüddecke, T.; Schulz, S.; Steinfartz, S.; Vences, M. | Journal Article |
2019 | Conversion of chitin to defined chitosan oligomers: Current status and future prospects Schmitz, C.; Auza, L.G.; Koberidze, D.; Rasche, S.; Fischer, R.; Bortesi, L. | Journal Article |
2019 | Correction to: Progress on bringing together raptor collections in Europe for contaminant research and monitoring in relation to chemicals regulation (Environmental Science and Pollution Research, (2019), 26, 20, (20132-20136), 10.1007/s11356-019-05340-6) Movalli, P.; Duke, G.; Ramello, G.; Dekker, R.; Vrezec, A.; Shore, R.F.; García-Fernández, A.; Wernham, C.; Krone, O.; Alygizakis, N.; Badry, A.; Barbagli, F.; Biesmeijer, K.; Boano, G.; Bond, A.L.; Choresh, Y.; Christensen, J.B.; Cincinelli, A.; Danielsson, S.; Dias, A.; Dietz, R.; Eens, M.; Espín, S.; Eulaers, I.; Frahnert, S.; Fuiz, T.I.; Gkotsis, G.; Glowacka, N.; Gómez-Ramírez, P.; Grotti, M.; Guiraud, M.; Hosner, P.; Johansson, U.; Jaspers, V.L.B.; Kamminga, P.; Koschorreck, J.; Knopf, B.; Kubin, E.; Brutto, S.L.; Lourenco, R.; Martellini, T.; Martínez-López, E.; Mateo, R.; Nika, M.-C.; Nikolopoulou, V.; Osborn, D.; Pauwels, O.; Pavia, M.; Pereira, M.G.; Rüdel, H.; Sanchez-Virosta, P.; Slobodnik, J.; Sonne, C.; Thomaidis, N.; Töpfer, T.; Treu, G.; Väinölä, R.; Valkama, J.; Mije, S. van der; Vangeluwe, D.; Warren, B.H.; Woog, F. | Journal Article |
2019 | The Correlation Between DsRed mRNA Levels and Transient DsRed Protein Expression in Plants Depends on Leaf Age and the 5′ Untranslated Region Jansing, J.; Buyel, J.F. | Journal Article |
2019 | Critical analysis of the commercial potential of plants for the production of recombinant proteins Schillberg, S.; Raven, N.; Spiegel, H.; Rasche, S.; Buntru, M. | Journal Article |
2019 | Curvature induction and membrane remodeling by FAM134B reticulon homology domain assist selective ER-phagy Bhaskara, R.M.; Grumati, P.; Garcia-Pardo, J.; Kalayil, S.; Covarrubias-Pinto, A.; Chen, W.; Kudryashev, M.; Dikic, I.; Hummer, G. | Journal Article |
2019 | CXCL16/CXCR6-mediated adhesion of human peripheral blood mononuclear cells to inflamed endothelium Linke, B.; Meyer Dos Santos, S.; Picard-Willems, B.; Keese, M.; Harder, S.; Geisslinger, G.; Scholich, K. | Journal Article |
2019 | CYRI/FAM49B negatively regulates RAC1-driven cytoskeletal remodelling and protects against bacterial infection Yuki, K.E.; Marei, H.; Fiskin, E.; Eva, M.M.; Gopal, A.A.; Schwartzentruber, J.A.; Majewski, J.; Cellier, M.; Mandl, J.N.; Vidal, S.M.; Malo, D.; Dikic, I. | Journal Article |
2019 | Cytokine-induced endogenous production of prostaglandin D2 is essential for human group 2 innate lymphoid cell activation Maric, J.; Ravindran, A.; Mazzurana, L.; Acker, A. van; Rao, A.; Kokkinou, E.; Ekoff, M.; Thomas, D.; Fauland, A.; Nilsson, G.; Wheelock, C.E.; Dahlen, S.-E.; Ferreiros, N.; Geisslinger, G.; Friberg, D.; Heinemann, A.; Konya, V.; Mjösberg, J. | Journal Article |
2019 | A Data Science-Based Analysis Points at Distinct Patterns of Lipid Mediator Plasma Concentrations in Patients with Dementia Gurke, R.; Etyemez, S.; Prvulovic, D.; Thomas, D.; Fleck, S.C.; Reif, A.; Geisslinger, G.; Lötsch, J. | Journal Article |
2019 | Degradation and transformation of fluoroquinolones by microorganisms with special emphasis on ciprofloxacin Rusch, M.; Spielmeyer, A.; Zorn, H.; Hamscher, G. | Journal Article |
2019 | Description of a new Moridilla species from North Sulawesi, Indonesia (Mollusca: Nudibranchia: Aeolidioidea) - based on MicroCT, histological and molecular analyses Schillo, D.; Wipfler, B.; Undap, N.; Papu, A.; Böhringer, N.; Eisenbarth, J.-H.; Kaligis, F.; Bara, R.; Schäberle, T.F.; König, G.M.; Wägele, H. | Journal Article |
2019 | Description of defensive postures of the natterjack toad epidalea calamita (Laurenti 1768) and notes on the release of toxic secretions Stawikowski, R.; Lüddecke, T. | Journal Article |
2019 | Determination of endocannabinoids and endocannabinoid-like substances in human K3EDTA plasma - LC-MS/MS method validation and pre-analytical characteristics Gurke, R.; Thomas, D.; Schreiber, Y.; Schäfer, S.M.G.; Fleck, S.C.; Geisslinger, G.; Ferreiros, N. | Journal Article |
2019 | Deubiquitinase USP10 regulates Notch signaling in the endothelium Lim, R.; Sugino, T.; Nolte, H.; Andrade, J.; Zimmermann, B.; Shi, C.; Doddaballapur, A.; Ong, Y.T.; Wilhelm, K.; Fasse, J.W.D.; Ernst, A.; Kaulich, M.; Husnjak, K.; Boettger, T.; Guenther, S.; Braun, T.; Krüger, M.; Benedito, R.; Dikic, I.; Potente, M. | Journal Article |
2019 | Development of a metabolic pathway transfer and genomic integration system for the syngas-fermenting bacterium Clostridium ljungdahlii Philipps, G.; Vries, S. de; Jennewein, S. | Journal Article |
2019 | Development of multitarget agents possessing soluble epoxide hydrolase inhibitory activity Hiesinger, K.; Wagner, K.M.; Hammock, B.D.; Proschak, E.; Hwang, S.H. | Journal Article |
2019 | Development study of pectin/Surelease® solid microparticles for the delivery of L-alanyl-L-glutamine dipeptide Nova, M.V.; Nothnagel, L.; Thurn, M.; Travassos, P.B.; Herculano, L.S.; Bittencourt, P.R.S.; Novello, C.R.; Bazotte, R.B.; Wacker, M.G.; Bruschi, M.L. | Journal Article |
2019 | A dialysis-based in vitro drug release assay to study dynamics of the drug-protein transfer of temoporfin liposomes Wallenwein, C.M.; Villa Nova, M.; Janas, C.; Jablonka, L.; Gao, G.F.; Thurn, M.; Albrecht, V.; Wiehe, A.; Wacker, M.G. | Journal Article |
2019 | Discovery of a benzothiophene-flavonol halting miltefosine and antimonial drug resistance in Leishmania parasites through the application of medicinal chemistry, screening and genomics Borsari, C.; Jiménez-Antón, M.D.; Eick, J.; Bifeld, E.; Torrado, J.J.; Olías-Molero, A.I.; Corral, M.J.; Santarem, N.; Baptista, C.; Severi, L.; Gul, S.; Wolf, M.; Kuzikov, M.; Ellinger, B.; Reinshagen, J.; Witt, G.; Linciano, P.; Tait, A.; Costantino, L.; Luciani, R.; Tejera Nevado, P.; Zander-Dinse, D.; Franco, C.H.; Ferrari, S.; Moraes, C.B.; Cordeiro-da-Silva, A.; Ponterini, G.; Clos, J.; Alunda, J.M.; Costi, M.P. | Journal Article |
2019 | Discovery of the First in Vivo Active Inhibitors of the Soluble Epoxide Hydrolase Phosphatase Domain Kramer, JS.; Woltersdorf, S.; Duflot, T.; Hiesinger, K.; Lillich, FF.; Knoll, F.; Wittmann, SK.; Klingler, FM.; Brunst, S.; Chaikuad, A.; Morisseau, C.; Hammock, BD.; Buccellati, C.; Sala, A.; Rovati, GE.; Leuillier, M.; Fraineau, S.; Rondeaux, J.; Hernandez-Olmos, V.; Heering, J.; Merk, D.; Pogoryelov, D.; Steinhilber, D.; Knapp, S.; Bellien, J.; Proschak, E. | Journal Article |
2019 | Discovery pipelines for marine resources: An ocean of opportunity for biotechnology? Smith, D.; Buddie, A.G.; Goss, R.J.M.; Overmann, J.; Lepleux, C.; Brönstrup, M.; Kloareg, B.; Meiners, T.; Brennecke, P.; Ianora, A.; Bouget, F.-Y.; Gribbon, P.; Pina, M. | Journal Article |
2019 | Distal infraorbital nerve injury Hardt, S.; Fischer, C; Vogel, A.; Wilken-Schmitz, A.; Tegeder, I. | Journal Article |
2019 | Downstream processing of Cry4AaCter-induced inclusion bodies containing insect-derived antimicrobial peptides produced in Escherichia coli Hoffmann, D.; Eckhardt, D.; Gerlach, D.; Vilcinskas, A.; Czermak, P. | Journal Article |
2019 | Driving next-generation autophagy researchers towards translation (DRIVE), an international PhD training program on autophagy Kraft, C.; Boya, P.; Codogno, P.; Elazar, Z.; Eskelinen, E.-L.; Farres, J.; Kirkin, V.; Jungbluth, H.; Martinez, A.; Pless, O.; Primard, C.; Proikas-Cezanne, T.; Simonsen, A.; Reggiori, F. | Journal Article |
2019 | The Drosophila melanogaster antimicrobial peptides Mtk-1 and Mtk-2 are active against the malarial parasite Plasmodium falciparum Tonk, M.; Pierrot, C.; Cabezas-Cruz, A.; Rahnamaeian, M.; Khalife, J.; Vilcinskas, A. | Journal Article |
2019 | Effects of continuous theta-burst stimulation of the primary motor and secondary somatosensory areas on the central processing and the perception of trigeminal nociceptive input in healthy volunteers Annak, O.; Heidegger, T.; Walter, C.; Deichmann, R.; Nöth, U.; Hansen-Goos, O.; Ziemann, U.; Lötsch, J. | Journal Article |
2019 | The effects of gibberellic acid on allium cepa root tip meristematic cells Tütünoğlu, B.; Aksoy, Ö.; Özbek, R.; Uçkan, F. | Journal Article |
2019 | Efficacy Of Etanercept Over A Period Of 12 Months In The Routine Treatment Of Patients With RA, AxSpA, PsA Or Pso: Final Results Of A German Non-Interventional, Prospective, Multi-Center Study (Adequate) Feist, E.; Baraliakos, X.; Behrens, F.; Thaci, D.; Klopsch, T.; Plenske, A.; Blindzellner, L.K.; Meng, T.; Löschmann, P.A. | Abstract |
2019 | Elimination of HER3-expressing breast cancer cells using aptamer-siRNA chimeras Nachreiner, I.; Hussain, A.F.; Wullner, U.; Machuy, N.; Meyer, T.F.; Fischer, R.; Gattenlöhner, S.; Meinhold-Heerlein, I.; Barth, S.; Tur, M.K. | Journal Article |
2019 | Elucidation of chemical modifier reactivity towards peptides and proteins and the analysis of specific fragmentation by matrix‐assisted laser desorption/ionization collision‐induced dissociation tandem mass spectrometry Rühl, M.; Kühn, B.; Roos, J.; Maier, T.J.; Steinhilber, D.; Karas, M. | Journal Article, Conference Paper |
2019 | Endokrin wirksame Umweltchemikalien in Lebensmitteln Schäfers, C.; Licht, O.; Bitsch, A. | Journal Article |
2019 | Enhancement of Benzothiazoles as Pteridine Reductase-1 Inhibitors for the Treatment of Trypanosomatidic Infections Linciano, P.; Pozzi, C.; Iacono, L. dello; Pisa, F. di; Landi, G.; Bonucci, A.; Gul, S.; Kuzikov, M.; Ellinger, B.; Witt, G.; Santarem, N.; Baptista, C.; Franco, C.; Moraes, C.B.; Müller, W.; Wittig, U.; Luciani, R.; Sesenna, A.; Quotadamo, A.; Ferrari, S.; Pöhner, I.; Cordeiro-da-Silva, A.; Mangani, S.; Costantino, L.; Costi, M.P. | Journal Article |
2019 | Environmental contamination with persistent cyclic mustard gas impurities and transformation products Chmielińska, Katarzyna; Hubé, Daniel; Bausinger, Tobias; Simon, Markus; Rivière, Gilles; Fauser, Patrik; Sanderson, Hans | Journal Article |
2019 | The enzymes OSC1 and CYP716A263 produce a high variety of triterpenoids in the latex of Taraxacum koksaghyz Pütter, K.M.; Deenen, N. van; Müller, B.; Fuchs, L.; Vorwerk, K.; Unland, K.; Bröker, J.N.; Scherer, E.; Huber, C.; Eisenreich, W.; Prüfer, D.; Schulze Gronover, C. | Journal Article |
2019 | Epigenetic Mechanisms Are Involved in Sex-Specific Trans-Generational Immune Priming in the Lepidopteran Model Host Manduca sexta Gegner, J.; Baudach, A.; Mukherjee, K.; Halitschke, R.; Vogel, H.; Vilcinska, A. | Journal Article |
2019 | Epigenetic mechanisms mediate the experimental evolution of resistance against parasitic fungi in the greater wax moth Galleria mellonella Mukherjee, K.; Dubovskiy, I.; Grizanova, E.; Lehmann, R.; Vilcinskas, A. | Journal Article |
2019 | ER-Mitochondria Communication in Cells of the Innate Immune System Namgaladze, D.; Khodzhaeva, V.; Brüne, B. | Journal Article |
2019 | EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology Brennecke, P.; Rasina, D.; Aubi, O.; Herzog, K.; Landskron, J.; Cautain, B.; Vicente, F.; Quintana, J.; Mestres, J.; Stechmann, B.; Ellinger, B.; Brea, J.; Kolanowski, J.L.; Pilarski, R.; Orzaez, M.; Pineda-Lucena, A.; Laraia, L.; Nami, F.; Zielenkiewicz, P.; Paruch, K.; Hansen, E.; Kries, J.P. von; Neuenschwander, M.; Specker, E.; Bartunek, P.; Simova, S.; Lesnikowski, Z.; Krauss, S.; Lehtio, L.; Bilitewski, U.; Bronstrup, M.; Tasken, K.; Jirgensons, A.; Lickert, H.; Clausen, M.H.; Andersen, J.H.; Vicent, M.J.; Genilloud, O.; Martinez, A.; Nazare, M.; Fecke, W.; Gribbon, P. | Journal Article |
2019 | Evaluation of microbial shifts caused by a silver nanomaterial: Comparison of four test systems Hund-Rinke, Kerstin; Hümmler, Anna; Schlinkert, Ruben; Wege, Franziska; Broll, Gabriele | Journal Article |
2019 | Evolutionary ecology of parasitic fungi and their host insects Vilcinskas, A. | Journal Article |
2019 | Fast Multiplex real time PCR method for sex-identification of medaka (Oryzias latipes) by non-invasive sampling Diaz, C.; Böhle, G.; Wege, F.; Teigeler, M.; Eilebrecht, E. | Journal Article |
2019 | Fate of a perfluoroalkyl acid mixture in an agricultural soil studied in lysimeters McLachlan, M.S.; Felizeter, S.; Klein, M.; Kotthoff, M.; Voogt, P. de | Journal Article |
2019 | First evidence of anticoagulant rodenticides in fish and suspended particulate matter: Spatial and temporal distribution in German freshwater aquatic systems Kotthoff, Matthias; Rüdel, Heinz; Jürling, Heinrich; Severin, Kevin; Hennecke, Stephan; Friesen, Anton; Koschorreck, Jan | Journal Article |
2019 | First Survey of Heterobranch Sea Slugs (Mollusca, Gastropoda) from the Island Sangihe, North Sulawesi, Indonesia Undap, N.; Papu, A.; Schillo, D.; Ijong, F.G.; Kaligis, F.; Lepar, M.; Hertzer, C.; Böhringer, N.; König, G.M.; Schäberle, T.F.; Wägele, H. | Journal Article |
2019 | Flow cytometry-based FRET identifies binding intensities in PPARγ1 protein-protein interactions in living cells Trümper, V.; Knethen, A. von; Preuß, A.; Ermilov, E.; Hackbarth, S.; Kuchler, L.; Gunne, S.; Schäfer, A.; Bornhütter, T.; Vereb, G.; Ujlaky-Nagy, L.; Brüne, B.; Röder, B.; Schindler, M.; Parnham, M.J.; Knape, T. | Journal Article |
2019 | Forced degradation studies to identify critical process parameters for the purification of infectious measles virus Loewe, D.; Häussler, J.; Grein, T.A.; Dieken, H.; Weidner, T.; Salzig, D.; Czermak, P. | Journal Article |
2019 | Förderung der Wiederbepflanzung von Windbruchflächen im Sauerland Drabkin, Dimitri; Weinfurtner, Karlheinz | Book Article |
2019 | Fraunhofer-Institut für Molekularbiologie und Angewandte Oekologie. Jahresbericht 2018 | Annual Report |
2019 | Functional Dominance of CHIP-Mutated Hematopoietic Stem Cells in Patients Undergoing Autologous Transplantation Ortmann, C.A.; Dorsheimer, L.; Abou-El-Ardat, K.; Hoffrichter, J.; Assmus, B.; Bonig, H.; Scholz, A.; Pfeifer, H.; Martin, H.; Schmid, T.; Brüne, B.; Scheich, S.; Steffen, B.; Riemann, J.; Hermann, S.; Dukat, A.; Bug, G.; Brandts, C.H.; Wagner, S.; Serve, H.; Rieger, M.A. | Journal Article |
2019 | Generation of transgenic cell suspension cultures of the model legume Medicago truncatula: A rapid method for Agrobacterium mediated gene transfer Santos, Rita B.; Pires, Ana Sofia; Hoorn, Renier A.L. van der; Schiermeyer, Andreas; Abranches, Rita | Journal Article |
2019 | Genome analysis of the marine bacterium Labrenzia sp. strain 011, a potential protective agent of mollusks Moghaddam, J.A.; Dávila-Céspedes, A.; Alanjary, M.; Blom, J.; König, G.M.; Schäberle, T.F. | Journal Article |
2019 | Genome Editing in Agriculture: Technical and Practical Considerations Jansing, Julia; Schiermeyer, Andreas; Schillberg, Stefan; Fischer, Rainer; Bortesi, Luisa | Journal Article |
2019 | Genomic targeting by recombinase‐mediated cassette exchange in the spotted wing drosophila, Drosophila suzukii Schetelig, M.F.; Yan, Y.; Zhao, Y.; Handler, A.M. | Journal Article |
2019 | Gliotoxin from Aspergillus fumigatus Abrogates Leukotriene B4 Formation through Inhibition of Leukotriene A4 Hydrolase König, S.; Pace, S.; Pein, H.; Heinekamp, T.; Kramer, J.; Romp, E.; Straßburger, M.; Troisi, F.; Proschak, A.; Dworschak, J.; Scherlach, K.; Rossi, A.; Sautebin, L.; Haeggström, J.Z.; Hertweck, C.; Brakhage, A.A.; Gerstmeier, J.; Proschak, E.; Werz, O. | Journal Article |
2019 | GLP-1 levels predict cardiovascular risk in patients with acute myocardial infarction Kahles, F.; Ruckbeil, M.V.; Mertens, R.W.; Foldenauer, A.C.; Arrivas, M.C.; Moellmann, J.; Lebherz, C.; Biener, M.; Giannitsis, E.; Katus, H.A.; Marx, N.; Lehrke, M. | Abstract |
2019 | GPER1 influences cellular homeostasis and cytostatic drug resistance via influencing long chain ceramide synthesis in breast cancer cells Wegner, M.-S.; Gruber, L.; Schömel, N.; Trautmann, S.; Brachtendorf, S.; Fuhrmann, D.; Schreiber, Y.; Olesch, C.; Brüne, B.; Geisslinger, G.; Grösch, S. | Journal Article |
2019 | High Treatment Satisfaction Of Therapy With Ustekinumab In Patients With Active Psoriatic Arthritis Due To Early And Long-Term Treatment Response And High Tolerability – Results Of The Non-Interventional Study Sustain Wendler, J.; Wagener, P.; Hamann, F.; Damann, N.; Movshovich, E.; Behrens, F. | Abstract |
2019 | High-Throughput Fluorescence Polarization Assay to Identify Ligands Using Purified G Protein-Coupled Receptor Heine, P.; Witt, G.; Gilardi, A.; Gribbon, P.; Kummer, L.; Plückthun, A. | Journal Article |
2019 | Histone Deacetylation Inhibitors as Therapy Concept in Sepsis. Review Knethen, A. von; Brüne, B. | Journal Article |
2019 | Hitze stabilisiert Malariaimpfstoffkandidaten in komplexen Proteinextrakten Buyel, J.F. | Journal Article |
2019 | Identification and characterization of approved drugs and drug-like compounds as covalent Escherichia coli ClpP inhibitors Sassetti, E.; Durante Cruz, C.; Tammela, P.; Winterhalter, M.; Augustyns, K.; Gribbon, P.; Windshügel, B. | Journal Article |
2019 | Identification of novel agonists by high-throughput screening and molecular modelling of human constitutive androstane receptor isoform 3 Keminer, O.; Windshügel, B.; Essmann, F.; Lee, S.M.L.; Schiergens, T.S.; Schwab, M.; Burk, O. | Journal Article |
2019 | Identification of the novel class D β-lactamase OXA-679 involved in carbapenem resistance in Acinetobacter calcoaceticus Tietgen, M.; Kramer, J.S.; Brunst, S.; Djahanschiri, B.; Wohra, S.; Higgins, P.G.; Weidensdorfer, M.; Riedel-Christ, S.; Pos, K.M.; Gonzaga, A.; Steglich, M.; Nübel, U.; Ebersberger, I.; Proschak, E.; Göttig, S. | Journal Article |
2019 | IL-38 Ameliorates Skin Inflammation and Limits IL-17 Production from γδ T Cells Han, Y.; Mora, J.; Huard, A.; Silva, P. da; Wiechmann, S.; Putyrski, M.; Schuster, C.; Elwakeel, E.; Lang, G.; Scholz, A.; Scholz, T.; Schmid, T.; Bruin, N. de; Billuart, P.; Sala, C.; Burkhardt, H.; Parnham, M.J.; Ernst, A.; Brüne, B.; Weigert, A. | Journal Article |
2019 | Imatinib stimulates prostaglandin E2 and attenuates cytokine release via EP4 receptor activation Bärnthaler, T.; Jandl, K.; Sill, H.; Uhl, B.; Schreiber, Y.; Grill, M.; Thomas, D.; Schicho, R.; Marsche, G.; Frank, S.; Heinemann, A.; Schuligoi, R. | Journal Article |
2019 | Immunogenicity assay development and validation for biological therapy as exemplified by ustekinumab Mojtahed Poor, S.; Ulshöfer, T.; Gabriel, L.A.; Henke, M.; Köhm, M.; Behrens, F.; Geisslinger, G.; Parnham, M.J.; Burkhardt, H.; Schiffmann, S. | Journal Article |
2019 | The immunome of soy bean allergy: Comprehensive identification and characterization of epitopes Kern, Karolin; Havenith, Heide; Delaroque, Nicolas; Rautenberger, Paul; Lehmann, Jörg; Fischer, Markus; Spiegel, Holger; Schillberg, Stefan; Ehrentreich-Förster, Eva; Aurich, Stefanie; Treudler, Regina; Szardenings, Michael | Journal Article |
2019 | Impact of Acid-Reducing Agents on Gastrointestinal Physiology and Design of Biorelevant Dissolution Tests to Reflect These Changes Segregur, D.; Flanagan, T.; Mann, J.; Moir, A.; Karlsson, E.M.; Hoch, M.; Carlile, D.; Sayah-Jeanne, S.; Dressman, J. | Journal Article |
2019 | Implantable wireless biometric animal telemetry system: a powerful tool to improve translational sepsis research Knape, T.; Wilken-Schmitz, A.; Schneider, A.K.; Arne, O.; Schmidt, M.; Götze, L.; Hofmann, M.C.J.; Bruin, N.M.W.J. de; Gerdes, C.; Glenschek-Sieberth, M.; Schmidt, M.V.; Remie, R.; Brill, B.; Parnham, M.J.; Knethen, A. von | Abstract |
2019 | In‐vitro–in‐silico investigation of the negative food effect of zolpidem when administered as immediate‐release tablets Paraiso, R.L.M.; Watanabe, A.; Andreas, C.J.; Turner, D.; Zane, P.; Dressman, J. | Journal Article |
2019 | Influence of methionine residue position on oxidative stability of glucose oxidase from Aspergillus niger Kovacevic, G.; Ostafe, R.; Fischer, R.; Prodanovic, R. | Journal Article |
2019 | Inhibition of the protein kinase IKKepsilon attenuates neuropathic pain in mice Möser, C.V.; Möller, M.; Fleck, S.C.; Thomas, D.; Geisslinger, G.; Niederberger, E. | Journal Article |
2019 | Insektenbiotechnologie: Insekten als Ressource Vilcinskas, Andreas | Book Article |
2019 | Integrating Drug- and Formulation-Related Properties With Gastrointestinal Tract Variability Using a Product-Specific Particle Size Approach Cristofoletti, R.; Hens, B.; Patel, N.; Esteban, V.V.; Schmidt, S.; Dressman, J. | Journal Article |
2019 | The Integration of Algal Carbon Concentration Mechanism Components into Tobacco Chloroplasts Increases Photosynthetic Efficiency and Biomass Nölke, G.; Barsoum, M.; Houdelet, M.; Arcalis, E.; Kreuzaler, F.; Fischer, R.; Schillberg, S. | Journal Article |
2019 | Iron as a Central Player and Promising Target in Cancer Progression. Review Jung, M.; Mertens, C.; Tomat, E.; Brüne, B. | Journal Article |
2019 | Iron-Dependent Trafficking of 5-Lipoxygenase and Impact on Human Macrophage Activation Dufrusine, B.; Di Francesco, A.; Oddi, S.; Scipioni, L.; Angelucci, C.B.; D'Addario, C.; Serafini, M.; Häfner, A.-K.; Steinhilber, D.; Maccarrone, M.; Dainese, E. | Journal Article |
2019 | Isolation and Identification of Alkaloids from Poisons of Fire Salamanders (Salamandra salamandra) Knepper, J.; Lüddecke, T.; Preißler, K.; Vences, M.; Schulz, S. | Journal Article |
2019 | Konzept zur Implementierung der neuen Umweltqualitätsnormen für prioritäre Stoffe in Fischen (Richtlinie 2013/39/EU). Abschlussbericht Radermacher, Georg; Fliedner, Annette; Rüdel, Heinz | Report |
2019 | Laccase-induced HBT-grafting to milled beech wood reduces unspecific protein adsorption Jestel, T.; Roth, S.; Heesel, D.; Kress, A.; Fischer, R.; Spiess, A.C. | Journal Article |
2019 | Levels, accumulation patterns and retrospective trends of perfluoroalkyl acids (PFAAs) in terrestrial ecosystems over the last three decades Falk, Sandy; Stahl, Thorsten; Fliedner, Annette; Rüdel, Heinz; Tarricone, Kathrin; Brunn, Hubertus; Koschorreck, Jan | Journal Article |
2019 | The Lipid Status in Patients with Ulcerative Colitis: Sphingolipids are Disease-Dependent Regulated Bazarganipour, S.; Hausmann, J.; Oertel, S.; El-Hindi, K.; Brachtendorf, S.; Blumenstein, I.; Kubesch, A.; Sprinzl, K.; Birod, K.; Hahnefeld, L.; Trautmann, S.; Thomas, D.; Herrmann, E.; Geisslinger, G.; Schiffmann, S.; Grösch, S. | Journal Article |
2019 | Long-term outdoor lysimeter study with cerium dioxide nanomaterial Hoppe, M.; Schlich, K.; Wielinski, J.; Köser, J.; Rückamp, D.; Kaegi, R.; Hund-Rinke, K. | Journal Article |
2019 | Loss of function mutation of the Rapid Alkalinization Factor (RALF1)-like peptide in the dandelion Taraxacum koksaghyz entails a high-biomass taproot phenotype Wieghaus, A.; Prüfer, D.; Schulze Gronover, C. | Journal Article |
2019 | Loxapine for treatment of patients with refractory, chemotherapy-induced neuropathic pain: A prematurely terminated pilot study showing efficacy but limited tolerability Schmiedl, S.; Peters, D.; Schmalz, O.; Mielke, A.; Rossmanith, T.; Diop, S.; Piefke, M.; Thürmann, P.; Schmidtko, A. | Journal Article |
2019 | Machine Learning in Human Olfactory Research Lötsch, J.; Kringel, D.; Hummel, T. | Journal Article |
2019 | A machine-learned analysis suggests non-redundant diagnostic information in olfactory subtests Lötsch, J.; Hummel, T. | Journal Article |
2019 | Macrophage HIF‐2α regulates tumor-suppressive Spint1 in the tumor microenvironment Susen, R.M.; Bauer, R.; Olesch, C.; Fuhrmann, D.C.; Fink, A.F.; Dehne, N.; Jain, A.; Ebersberger, I.; Schmid, T.; Brüne, B. | Journal Article |
2019 | Macrophage S1PR1 Signaling Alters Angiogenesis and Lymphangiogenesis During Skin Inflammation Syed, S.N.; Raue, R.; Weigert, A.; Knethen, A. von; Brüne, B. | Journal Article |
2019 | Maintaining hepatic PD-L1 expression improves sepsis survival in a murine polymicrobial sepsis model by tolerizing CTL Knethen, A. von; Schäfer, A.; Kuchler, L.; Knape, T.; Christen, U.; Hintermann, E.; Fisslthaler, B.; Schröder, K.; Brandes, R.P.; Genz, B.; Abshagen, K.; Pützer, B.M.; Sha, L.K.; Weigert, A.; Syed, S.N.; Schulz, M.; Shah, A.M.; Ernst, A.; Putyrski, M.; Finkelmeier, F.; Pesic, M.; Greten, F.; Hoghardt, M.; Kempf, V.A.J.; Gunne, S.; Parnham, M.J.; Brüne, B. | Abstract |
2019 | Mass Spectrometry-Based Proteomics Approach Characterizes the Dual Functionality of miR-328 in Monocytes Saul, M.J.; Hegewald, A.B.; Emmerich, A.C.; Ossipova, E.; Vogel, M.; Baumann, I.; Kultima, K.; Lengqivst, J.; Steinhilber, D.; Jakobsson, P.J. | Journal Article |
2019 | Melleolides from Honey Mushroom Inhibit 5-Lipoxygenase via Cys159 König, S.; Romp, E.; Krauth, V.; Rühl, M.; Dörfer, M.; Liening, S.; Hofmann, B.; Häfner, A.-K.; Steinhilber, D.; Karas, M.; Garscha, U.; Hoffmeister, D.; Werz, O. | Journal Article |
2019 | Members of the endocannabinoid system are distinctly regulated in inflammatory bowel disease and colorectal cancer Grill, M.; Högenauer, C.; Blesl, A.; Haybaeck, J.; Golob-Schwarzl, N.; Ferreirós, N.; Thomas, D.; Gurke, R.; Trötzmüller, M.; Köfeler, H.C.; Gallè, B.; Schicho, R. | Journal Article |
2019 | miR‐574‐5p as RNA decoy for CUGBP1 stimulates human lung tumor growth by mPGES‐1 induction Saul, M.J.; Baumann, I.; Bruno, A.; Emmerich, A.C.; Wellstein, J.; Ottinger, S.M.; Contursi, A.; Dovizio, M.; Donnini, S.; Tacconelli, S.; Raouf, J.; Idborg, H.; Stein, S.; Korotkova, M.; Savai, R.; Terzuoli, E.; Sala, G.; Seeger, W.; Jakobsson, P.-J.; Patrignani, P.; Suess, B.; Steinhilber, D. | Journal Article |
2019 | Molecular Targeting Therapy against EGFR Family in Breast Cancer. Progress and Future Potentials Maennling, A.E.; Tur, M.K.; Niebert, M.; Klockenbring, Torsten; Zeppernick, F.; Gattenlöhner, S.; Meinhold-Heerlein, I.; Hussain, A.F. | Journal Article |
2019 | Monoclonal Antibody AP3 Binds Galactomannan Antigens Displayed by the Pathogens Aspergillus flavus, A. fumigatus, and A. parasiticus Schubert, M.; Xue, S.; Ebel, F.; Vaggelas, A.; Krylov, V.B.; Nifantiev, N.E.; Chudobova, I.; Schillberg, S.; Nölke, G. | Journal Article |
2019 | More yellow more toxic? Sex rather than alkaloid content is correlated with yellow coloration in the fire salamander Preißler, K.; Gippner, S.; Lüddecke, T.; Krause, E.T.; Schulz, S.; Vences, M.; Steinfartz, S. | Journal Article |
2019 | The nanoGRAVUR framework to group (nano)materials for their occupational, consumer, environmental risks based on a harmonized set of material properties, applied to 34 case studies Wohlleben, W.; Hellack, B.; Nickel, C.; Herrchen, M.; Hund-Rinke, K.; Kettler, K.; Riebeling, C.; Haase, A.; Funk, B.; Kühnel, D.; Göhler, D.; Stintz, M.; Schumacher, C.; Wiemann, M.; Keller, J.; Landsiedel, R.; Brossell, D.; Pitzko, S.; Kuhlbusch, T.A.J. | Journal Article |
2019 | Nanomedicines - Tiny particles and big challenges Marques, M.R.C.; Choo, Q.; Ashtikar, M.; Rocha, T.C.; Bremer-Hoffmann, S.; Wacker, M.G. | Journal Article |
2019 | The need for comparative data in spondyloarthritis Choy, E.; Baraliakos, X.; Behrens, F.; D'Angelo, S.; Vlam, K. de; Kirkham, B.W.; Ostergaard, M.; Schett, G.A.; Rissler, M.; Chaouche-Teyara, K.; Perella, C. | Journal Article |
2019 | New insights into the prevalence of depressive symptoms and depression in rheumatoid arthritis Englbrecht, M.; Alten, R.; Aringer, M.; Baerwald, C.G.; Burkhardt, H.; Eby, N.; Flacke, J.-P.; Fliedner, G.; Henkemeier, U.; Hofmann, M.W.; Kleinert, S.; Kneitz, C.; Krüger, K.; Pohl, C.; Schett, G.; Schmalzing, M.; Tausche, A.-K.; Tony, H.-P.; Wendler, J. | Journal Article |
2019 | A new lipoxygenase from the agaric fungus Agrocybe aegerita: Biochemical characterization and kinetic properties Karrer, D.; Rühl, M. | Journal Article |
2019 | A new sesquiterpenoid aminoquinone from an Indonesian marine sponge Balansa, W.; Mettal, U.; Wuisan, Z.G.; Plubrukarn, A.; Ijong, F.G.; Liu, Y.; Schäberle, T.F. | Journal Article |
2019 | New terpenoids from the fermentation broth of the edible mushroom Cyclocybe aegerita Surup, F.; Hennicke, F.; Sella, N.; Stroot, M.; Bernecker, S.; Pfütze, S.; Stadler, M.; Rühl, M. | Journal Article |
2019 | Non-invasive imaging and modeling of liver regeneration after partial hepatectomy Zafarnia, S.; Mrugalla, A.; Rix, A.; Doleschel, D.; Gremse, F.; Wolf, S.D.; Buyel, J.F.; Albrecht, U.; Bode, J.G.; Kiessling, F.; Lederle, W. | Journal Article |
2019 | Novel Approaches to Persistent Pain Therapy Sisignano, M.; Parnham, M.J.; Geisslinger, G. | Journal Article |
2019 | A novel in vivo predictive dissolution testing coupled with a modeling and simulation for hydrogel matrix monolithic extended release oral dosage forms Kambayashi, A.; Dressman, J.B. | Journal Article |
2019 | Nutzung der Erfahrungen und Ergebnisse des Biotamonitorings der Umweltprobenbank für die Umsetzung des WRRL-Fischmonitorings Fliedner, Annette; Rüdel, Heinz; Koschorreck, Jan | Journal Article |
2019 | Omega-3 and -6 fatty acid plasma levels are not associated with liver cirrhosis-associated systemic inflammation Schwarzkopf, K.M.; Queck, A.; Thomas, D.; Angioni, C.; Cai, C.; Freygang, Y.; Rüschenbaum, S.; Geisslinger, G.; Zeuzem, S.; Welsch, C.; Lange, C.M. | Journal Article |
2019 | Opportunities for Successful Stabilization of Poor Glass-Forming Drugs: A Stability-Based Comparison of Mesoporous Silica Versus Hot Melt Extrusion Technologies Ditzinger, F.; Price, D.J.; Nair, A.; Becker-Baldus, J.; Glaubitz, C.; Dressman, J.; Saal, C.; Kuentz, M. | Journal Article |
2019 | Organismen als Produzenten: Produktion von Wertstoffen mithilfe von Mikroorganismen, Algen und Pflanzenzellen Rasche, Stefan; Schillberg, Stefan; Derwenskus, Felix; Schmid-Staiger, Ulrike; Schließmann, Ursula | Book Article |
2019 | Oxidosqualene cyclase knock-down in latex of taraxacum koksaghyz reduces triterpenes in roots and separated natural rubber Deenen, N. van; Unland, K.; Prüfer, D.; Schulze Gronover, C. | Journal Article |
2019 | Passive equilibrium sampling of hydrophobic organic compounds in homogenised fish tissues of low lipid content Rojo-Nieto, Elisa; Muz, Melis; Koschorreck, Jan; Rüdel, Heinz; Jahnke, Annika | Journal Article |
2019 | Pathogens associated with invasive or introduced insects threaten the health and diversity of native species Vilcinskas, A. | Journal Article |
2019 | PBPK modeling coupled with biorelevant dissolution to forecast the oral performance of amorphous solid dispersion formulations Kambayashi, A.; Kiyota, T.; Fujiwara, M.; Dressman, J. | Journal Article |
2019 | Pflanzenschutzmittel im Grundwasser: Besteht ein Umweltrisiko? Schäfers, Christoph; Klein, Michael | Conference Paper |
2019 | Phenotypic Plasticity of Fibroblasts during Mammary Carcinoma Development Elwakeel, E.; Brüggemann, M.; Fink, A.F.; Schulz, M.H.; Schmid, T.; Savai, R.; Brüne, B.; Zarnack, K.; Weigert, A. | Journal Article |
2019 | Phylogeny-Guided Selection of Priority Groups for Venom Bioprospecting Lüddecke, T.; Vilcinskas, A.; Lemke, S. | Journal Article |
2019 | Plant cell packs: A scalable platform for recombinant protein production and metabolic engineering Rademacher, T.; Sack, M.; Blessing, D.; Fischer, R.; Holland, T.; Buyel, J. | Journal Article |
2019 | Plant Molecular Farming - Integration and Exploitation of Side Streams to Achieve Sustainable Biomanufacturing Buyel, J.F. | Journal Article |
2019 | Polypharmacology by Design: A Medicinal Chemist’s Perspective on Multitargeting Compounds Proschak, E.; Stark, H.; Merk, D. | Journal Article |
2019 | Potential biomarkers for persistent and neuropathic pain therapy Sisignano, M.; Lötsch, J.; Parnham, M.J.; Geisslinger, G. | Journal Article |
2019 | Practical advice for selecting or determining trophic magnification factors for application under the European Union water framework directive Kidd, K.A.; Burkhard, Lawrence P.; Babut, M.; Borgå, Katrine; Muir, Derek C.G.; Perceval, Olivier; Ruedel, Heinz; Woodburn, Kent; Embry, Michelle R. | Journal Article |
2019 | The precursor hypothesis of sponge kleptocnidism: Development of nematocysts in Haliclona cnidata sp. nov. (porifera, demospongiae, haplosclerida) Schellenberg, J.; Reichert, J.; Hardt, M.; Schmidtberg, H.; Kämpfer, P.; Glaeser, S.P.; Schubert, P.; Wilke, T. | Journal Article |
2019 | Predicting the Changes in Oral Absorption of Weak Base Drugs Under Elevated Gastric pH Using an In Vitro-In Silico-In Vivo Approach Kambayashi, A.; Dressman, J.B. | Journal Article |
2019 | Predictive PBPK modeling as a tool in the formulation of the drug candidate TMP-001 Nothnagel, L.; Jung, F.; Rossmanith, T.; Thurn, M.; Ashtikar, M.; Geisslinger, G.; Parnham, M.J.; Wacker, M.G. | Journal Article |
2019 | Probability Of Achieving Low Disease Activity Or Remission In Subjects With Active Psoriatic Arthritis Treated With Apremilast Mease, P.J.; Behrens, F.; Gladman, D.D.; Kavanaugh, A.; Brunori, M.; Teng, L.C.; Guerette, B.; Queiro, R.; Ogdie, A. | Abstract |
2019 | Process intensification for an insect antimicrobial peptide elastin-like polypeptide fusion produced in redox-engineered Escherichia coli Joachim, M.; Maguire, N.; Schäfer, J.; Gerlach, D.; Czermak, P. | Journal Article |
2019 | Processing Induced Degradation Routes of Prochloraz in Rapeseed Oil Göckener, Bernd; Kotthoff, Matthias; Kling, Hans-Willi; Bücking, Mark | Journal Article |
2019 | Profiling antimicrobial peptides from the medical maggot Lucilia sericata as potential antibiotics for MDR Gram-negative bacteria Hirsch, R.; Wiesner, J.; Marker, A.; Pfeifer, Y.; Bauer, A.; Hammann, P.E.; Vilcinskas, A. | Journal Article |
2019 | Progress on bringing together raptor collections in Europe for contaminant research and monitoring in relation to chemicals regulation Movalli, Paola; Duke, Guy; Ramello, Gloria; Dekker, René; Vrezec, Al; Shore, Richard F.; García-Fernández, Antonio; Wernham, Chris; Krone, Oliver; Alygizakis, Nikiforos; Badry, Alexander; Barbagli, Fausto; Biesmeijer, Koos; Boano, Giovanni; Bond, Alexander L.; Choresh, Yael; Bolding Christensen, Jan; Cincinelli, Alessandra; Danielsson, Sara; Dias, Andreia; Dietz, Rune; Eens, Marcel; Espín, Silvia; Eulaers, Igor; Frahnert, Sylke; Fuiz, Tibor I.; Gkotsis, Georgios; Glowacka, Natalia; Gómez-Ramírez, Pilar; Grotti, Marco; Guiraud, Michel; Hosner, Peter; Johansson, Ulf; Jaspers, Veerle L.B.; Kamminga, Pepijn; Koschorreck, Jan; Knopf, Burkhard; Kubin, Eero; LoBrutto, Sabrina; Lourenco, Rui; Martellini, Tania; Martínez-López, Emma; Mateo, Rafael; Nika, Maria-Christina; Nikolopoulou, Varvara; Osborn, Dan; Pauwels, Olivier; Pavia, Marco; Pereira, M. Glória; Rüdel, Heinz; Sanchez-Virosta, Pablo; Slobodnik, Jaroslav; Sonne, Christian; Thomaidis, Nikolaos; Töpfer, Till; Treu, Gabriele; Väinölä, Risto; Valkama, | Journal Article |
2019 | Protection of the groundwater against loads of plant protection products: Validation of the new EU-simulation model FO-CUS PELMO 4 for a reliable prediction of the leaching potential of PPP into groundwater Klein, Michael; Thomas, Kai; Trapp, Matthias; Guerniche, Djamal | Report |
2019 | Protection of the groundwater against loads of plant protection products: Validation of the new EU-simulation model FO-CUS PELMO 4 for a reliable prediction of the leaching potential of PPP into groundwater Klein, Michael; Thomas, Kai; Trapp, Matthias; Guerniche, Djamal | Report |
2019 | Proteomic Analysis of the Venom from the Ruby Ant Myrmica rubra and the Isolation of a Novel Insecticidal Decapeptide Heep, J.; Klaus, A.; Kessel, T.; Seip, M.; Vilcinskas, A.; Skaljac, M. | Journal Article |
2019 | Psoriatic Arthritis Impact Of Disease Questionnaire Scores Are Correlated With Disease Activity, As Measured By cDAPSA, In Patients With Psoriatic Arthritis Orbai, A.M.; Krueger, K.; Behrens, F.; Kiltz, U.; Guerette, B.; Mellars, L.; Brunori, M.; Wollenhaupt, J. | Abstract |
2019 | Quantitative Phosphoproteomics of Selective Autophagy Receptors Juretschke, T.; Beli, P.; Dikic, I. | Book Article |
2019 | Rating the risks of anticoagulant rodenticides in the aquatic environment: A review Regnery, Julia; Friesen, Anton; Geduhn, Anke; Göckener, Bernd; Kotthoff, Matthias; Parrhysius, Pia; Petersohn, Eleonora; Reifferscheid, Georg; Schmolz, Erik; Schulz, Robert S.; Schwarzbauer, Jan; Brinke, Marvin | Journal Article |
2019 | Ready-to-Use Stocks of Agrobacterium tumefaciens can Simplify Process Development for the Production of Recombinant Proteins by Transient Expression in Plants Spiegel, H.; Boes, A.; Perales Morales, C.; Rademacher, T.; Buyel, J.F. | Journal Article |
2019 | Recent findings of halogenated flame retardants (HFR) in the German and Polar environment Dreyer, Annekatrin; Neugebauer, Frank; Lohmann, Nina; Rüdel, Heinz; Teubner, Diana; Grotti, Marco; Rauert, Caren; Koschorreck, Jan | Journal Article |
2019 | Redox regulation of PPAR gamma in polarized macrophages Trümper, V.; Wittig, I.; Heidler, J.; Brüne, B.; Knethen, A. von | Abstract |
2019 | Reduced neuropathic pain behavior in mice lacking the cyclic nucleotide-gated channel subunit CNGB1 Kallenborn-Gerhardt, W.; Lu, R.; Petersen, J.J.; Metzner, K.; Kuth, M.S.; Heine, S.; Drees, O.; Paul, M.; Becirovic, E.; Kennel, L.; Flauaus, C.; Gross, T.; Wack, G.; Hohmann, S.W.; Turco, D. del; Biel, M.; Geisslinger, G.; Michalakis, S.; Schmidtko, A. | Abstract |
2019 | A response regulator of the OmpR family is part of the regulatory network controlling the oxidative stress response of Rhodobacter sphaeroides Zhao, Z.; Peng, T.; Oh, J.-I.; Glaeser, J.; Weber, L.; Li, Q.; Klug, G. | Journal Article |
2019 | RNAi targeting of rootworm Troponin I transcripts confers root protection in maize Fishilevich, E.; Bowling, A.J.; Frey, M.L.F.; Wang, P.-H.; Lo, W.; Rangasamy, M.; Worden, S.E.; Pence, H.E.; Gandra, P.; Whitlock, S.L.; Schulenberg, G.; Knorr, E.; Tenbusch, L.; Lutz, J.R.; Novak, S.; Hamm, R.L.; Schnelle, K.D.; Vilcinskas, A.; Narva, K.E. | Journal Article |
2019 | Role of ceramide synthase 2 in G-CSF signaling and G-CSF-R translocation into detergent-resistant membranes Kurz, J.; Barthelmes, J.; Blum, L.; Ulshöfer, T.; Wegner, M.-S.; Ferreiros, N.; Roser, L.; Geisslinger, G.; Grösch, S.; Schiffmann, S. | Journal Article |
2019 | Russell-like bodies in plant seeds share common features with prolamin bodies and occur upon recombinant protein production Arcalis, E.; Ibl, V.; Hilscher, J.; Rademacher, T.; Avesani, L.; Morandini, F.; Bortesi, L.; Pezzotti, M.; Vitale, A.; Pum, D.; Meyer, T. de; Depicker, A.; Stoger, E. | Journal Article |
2019 | SAR Studies and Biological Characterization of a Chromen-4-one Derivative as an Anti- Trypanosoma brucei Agent Borsari, C.; Santarem, N.; Macedo, S.; Jiménez-Antón, M.D.; Torrado, J.J.; Olías-Molero, A.I.; Corral, M.J.; Tait, A.; Ferrari, S.; Costantino, L.; Luciani, R.; Ponterini, G.; Gul, S.; Kuzikov, M.; Ellinger, B.; Behrens, B.; Reinshagen, J.; Alunda, J.M.; Cordeiro-Da-Silva, A.; Costi, M.P. | Journal Article |
2019 | Selective Inactivation of Cancer Drugs by SAMHD1 Provides a Molecular Rationale for Therapeutic Stratification in AML Schneider, C.; Oellerich, T.; Knecht, K.M.; Thomas, D.; Buzovetsky, O.; Schliemann, C.; Bohnenberger, H.; Angenendt, L.; Hartmann, W.; Wardelmann, E.; Scheich, S.; Comoglio, F.; Wilke, A.; Ströbel, P.; Serve, H.; Geisslinger, G.; Keppler, O.T.; Xiong, Y.; Cinatl, J. | Abstract |
2019 | Selective inactivation of hypomethylating agents by SAMHD1 provides a rationale for therapeutic stratification in AML Oellerich, T.; Schneider, C.; Thomas, D.; Knecht, K.M.; Buzovetsky, O.; Kaderali, L.; Schliemann, C.; Bohnenberger, H.; Angenendt, L.; Hartmann, W.; Wardelmann, E.; Rothenburger, T.; Mohr, S.; Scheich, S.; Comoglio, F.; Wilke, A.; Ströbel, P.; Serve, H.; Michaelis, M.; Ferreiros, N.; Geisslinger, G.; Xiong, Y.; Keppler, O.T.; Cinatl, J. | Journal Article |
2019 | Sensitive and rapid detection of cholera toxin subunit B using magnetic frequency mixing detection Achtsnicht, S.; Neuendorf, C.; Faßbender, T.; Nölke, G.; Offenhäusser, A.; Krause, H.-J.; Schröper, F. | Journal Article |
2019 | Shooting three inflammatory targets with a single bullet: Novel multi-targeting anti-inflammatory glitazones Elzahhar, P.A.; Alaaeddine, R.; Ibrahim, T.M.; Nassra, R.; Ismail, A.; Chua, B.S.K.; Frkic, R.L.; Bruning, J.B.; Wallner, N.; Knape, T.; Knethen, A. von; Labib, H.; El-Yazbi, A.F.; Belal, A.S.F. | Journal Article |
2019 | The significance of comparative genomics in modern evolutionary venomics Drukewitz, S.H.; Reumont, B.M. von | Journal Article |
2019 | Simplified tracking of a soy allergen in processed food using a monoclonal antibody-based sandwich ELISA targeting the soybean 2S albumin gly m 8 Ueberham, Elke; Spiegel, Holger; Havenith, Heide; Rautenberger, Paul; Lidzba, Norbert; Schillberg, Stefan; Lehmann, Jörg | Journal Article |
2019 | Sphingosine kinase 2 is a negative regulator of inflammatory macrophage activation Weigert, A.; Knethen, A. von; Thomas, D.; Faria, I.; Namgaladze, D.; Zezina, E.; Fuhrmann, D.; Petcherski, A.; Meyer zu Heringdorf, D.; Radeke, H.H.; Brüne, B. | Journal Article |
2019 | Sphingosine-1-Phosphate and Macrophage Biology - How the Sphinx Tames the Big Eater Weigert, A.; Olesch, C.; Brüne, B. | Journal Article |
2019 | Stability of Biorelevant Media Under Various Storage Conditions Klumpp, L.; Nagasekar, K.; McCullough, O.; Seybert, A.; Ashtikar, M.; Dressman, J. | Journal Article |
2019 | Stimulating brain recovery after stroke using theranostic albumin nanocarriers loaded with nerve growth factor in combination therapy Feczkó, T.; Piiper, A.; Ansar, S.; Blixt, F.W.; Ashtikar, M.; Schiffmann, S.; Ulshöfer, T.; Parnham, M.J.; Harel, Y.; Israel, L.L.; Lellouche, J.-P.; Wacker, M.G. | Journal Article |
2019 | Strategies to Interfere with Tumor Metabolism through the Interplay of Innate and Adaptive Immunity Mora, J.; Mertens, C.; Meier, J.K.; Fuhrmann, D.C.; Brüne, B.; Jung, M. | Journal Article |
2019 | Structural insights into ligand-binding pocket formation in Nurr1 by molecular dynamics simulations Windshügel, B. | Journal Article |
2019 | Structural Insights into the Development of Cycloguanil Derivatives as Trypanosoma brucei Pteridine-Reductase-1 Inhibitors Landi, G.; Linciano, P.; Borsari, C.; Bertolacini, C.P.; Moraes, C.B.; Cordeiro-da-Silva, A.; Gul, S.; Witt, G.; Kuzikov, M.; Costi, M.P.; Pozzi, C.; Mangani, S. | Journal Article |
2019 | Structure optimization of a new class of PPARγ antagonists Hernandez-Olmos, V.; Knape, T.; Heering, J.; Knethen, A. von; Kilu, W.; Kaiser, A.; Wurglics, M.; Helmstadter, M.; Merk, D.; Schubert-Zsilavecz, M.; Parnham, M.J.; Steinhilber, D.; Proschak, E. | Journal Article |
2019 | Surface Acoustic Wave-Based Microfluidic Coagulation Device for Monitoring Anticoagulant Therapy Harder, S.; Meyer dos Santos, S.; Krozer, V.; Moll, J. | Journal Article |
2019 | Surface Activity Profiling (SAP): A potential means of predicting intestinal membrane permeability Rosenberger, J.; Schmid, K.; Schäfer, K.J.; Dressman, J. | Journal Article |
2019 | Symbiont‐mediated chemical defense in the invasive ladybird Harmonia axyridis Schmidtberg, H.; Shukla, S.P.; Halitschke, R.; Vogel, H.; Vilcinskas, A. | Journal Article |
2019 | Synthesis, Biological Evaluation and Structure: Activity Relationships of Diflapolin Analogues as Dual sEH/FLAP Inhibitors Vieider, L.; Romp, E.; Temml, V.; Fischer, J.; Kretzer, C.; Schoenthaler, M.; Taha, A.; Hernandez-Olmos, V.; Sturm, S.; Schuster, D.; Werz, O.; Garscha, U.; Matuszczak, B. | Journal Article |
2019 | Tarantula phylogenomics: A robust phylogeny of deep theraphosid clades inferred from transcriptome data sheds light on the prickly issue of urticating setae evolution Foley, S.; Lüddecke, T.; Cheng, D.-Q.; Krehenwinkel, H.; Künzel, S.; Longhorn, S.J.; Wendt, I.; Wirth, V. von; Tänzler, R.; Vences, M.; Piel, W.H. | Journal Article |
2019 | Targeted insertion of large DNA sequences by homology-directed repair or non-homologous end joining in engineered tobacco BY-2 cells using designed zinc finger nucleases Schiermeyer, Andreas; Schneider, Katja; Kirchhoff, Janina; Schmelter, Thomas; Koch, Natalie; Ke, Jiang; Herwartz, Denise; Blue, Ryan; Marri, Pradeep; Samuel, Pon; Corbin, David R.; Webb, Steven R.; Gonzalez, Delkin O.; Folkerts, Otto; Fischer, Rainer; Schinkel, Helga; Ainley, W. Michael; Schillberg, Stefan | Journal Article |
2019 | Targeted lipidomics reveal derangement of ceramides in major depression and bipolar disorder Brunkhorst-Kanaan, N.; Klatt-Schreiner, K.; Hackel, J.; Schröter, K.; Trautmann, S.; Hahnefeld, L.; Wicker, S.; Reif, A.; Thomas, D.; Geisslinger, G.; Kittel-Schneider, S.; Tegeder, I. | Journal Article |
2019 | Testing effects of pesticides on macroinvertebrate communities in outdoor stream mesocosms using carbaryl as example test item Beuter, Liesa‑Kristin; Dören, László; Hommen, Udo; Kotthoff, Matthias; Schäfers, Christoph; Ebke, Klaus-Peter | Journal Article |
2019 | The therapeutic potential of the insect metalloproteinase inhibitor against infections caused by Pseudomonas aeruginosa Eisenhardt, M.; Schlupp, P.; Höfer, F.; Schmidts, T.; Hoffmann, D.; Czermak, P.; Pöppel, A.-K.; Vilcinskas, A.; Runkel, F. | Journal Article |
2019 | Thromboxane-Induced α-CGRP Release from Peripheral Neurons Is an Essential Positive Feedback Loop in Capsaicin-Induced Neurogenic Inflammation Tarighi, N.; Menger, D.; Pierre, S.; Kornstädt, L.; Thomas, D.; Ferreiros, N.; Nüsing, R.M.; Geisslinger, G.; Scholich, K. | Journal Article |
2019 | Tissue Cytokine IL-33 Modulates the Cytotoxic CD8 T Lymphocyte Activity During Nutrient Deprivation by Regulation of Lineage-Specific Differentiation Programs Dreis, C.; Ottenlinger, F.M.; Putyrski, M.; Ernst, A.; Huhn, M.; Schmidt, K.G.; Pfeilschifter, J.M.; Radeke, H.H. | Journal Article |
2019 | Tolerizing CTL by Sustained Hepatic PD-L1 Expression Provides a New Therapy Approach in Mouse Sepsis Knethen, A. von; Schäfer, A.; Kuchler, L.; Knape, T.; Christen, U.; Hintermann, E.; Fißlthaler, B.; Schröder, K.; Brandes, R.P.; Genz, B.; Abshagen, K.; Pützer, B.M.; Sha, L.K.; Weigert, A.; Syed, S.N.; Schulz, M.; Shah, A.M.; Ernst, A.; Putyrski, M.; Finkelmeier, F.; Pesic, M.; Greten, F.; Hogardt, M.; Kempf, V.A.J.; Gunne, S.; Parnham, M.J.; Brüne, B. | Journal Article |
2019 | Toxins from scratch? Diverse, multimodal gene origins in the predatory robber fly Dasypogon diadema indicate a dynamic venom evolution in dipteran insects Drukewitz, S.H.; Bokelmann, L.; Undheim, E.A.B.; Reumont, B.M. von | Journal Article |
2019 | Transcriptome sequencing of a keystone aquatic herbivore yields insights on the temperature-dependent metabolism of essential lipids Windisch, Heidrun S.; Fink, Patrick | Journal Article |
2019 | Transmission of a protease-secreting bacterial symbiont among pea aphids via host plants Skaljac, M.; Vogel, H.; Wielsch, N.; Mihajlovic, S.; Vilcinskas, A. | Journal Article |
2019 | Tribolium castaneum as a whole‐animal screening system for the detection and characterization of neuroprotective substances Brandt, A.; Joop, G.; Vilcinskas, A. | Journal Article |
2019 | TRPA1 Sensitization Produces Hyperalgesia to Heat but not to Cold Stimuli in Human Volunteers Weyer-Menkhoff, I.; Lötsch, J. | Journal Article |
2019 | Tunicate-associated bacteria show a great potential for the discovery of antimicrobial compounds Ayuningrum, D.; Liu, Y.; Riyanti; Sibero, M.T.; Kristiana, R.; Asagabaldan, M.A.; Wuisan, Z.G.; Trianto, A.; Radjasa, O.K.; Sabdono, A.; Schaberle, T.F. | Journal Article |
2019 | Tuning Nuclear Receptor Selectivity of Wy14,643 towards Selective Retinoid X Receptor Modulation Pollinger, J.; Gellrich, L.; Schierle, S.; Kilu, W.; Schmidt, J.; Kalinowsky, L.; Ohrndorf, J.; Kaiser, A.; Heering, J.; Proschak, E.; Merk, D. | Journal Article |
2019 | Two-step production of neofructo-oligosaccharides using immobilized heterologous aspergillus terreus 1f-fructosyltransferase expressed in Kluyveromyces lactis and native Xanthophyllomyces dendrorhous G6-fructosyltransferase Burghardt, J.P.; Baas, M.; Gerlach, D.; Czermak, P. | Journal Article |
2019 | Uncovering mechanisms of rubber biosynthesis in Taraxacum koksaghyz - role of cis-prenyltransferase-like 1 protein Niephaus, E.; Müller, B.; Deenen, N. van; Lassowskat, I.; Bonin, M.; Finkemeier, I.; Prüfer, D.; Schulze Gronover, C. | Journal Article |
2019 | Untersuchung von Pestizidabbauprodukten während der Lebensmittelverarbeitung Göckener, Bernd : Bücking, Mark; Kling, Hans-Willi; Kotthoff, Matthias | Dissertation |
2019 | A validated LC-MS/MS method for the determination of homocysteic acid in biological samples Gurke, R.; Schmidt, D.; Thomas, D.; Fleck, S.C.; Geisslinger, G.; Ferreiros, N. | Journal Article |
2019 | Verhalten nanomaterialhaltiger Schlacken und Aschen aus Müllverbrennung und Klärschlammverbrennung Oischinger, Jürgen; Meisterjahn, Boris | Presentation |
2019 | Versorgungssituation von Patienten mit ankylosierender Spondylitis und Psoriasisarthritis in Deutschland Braun, J.; Schwarting, A.; Hammel, L.; Legeler, C.; Wimmer, P.; Färber, L.; Behrens, F. | Journal Article |
2019 | Visualizing ubiquitination in mammalian cells Wijk, S.J. van; Fulda, S.; Dikic, I.; Heilemann, M. | Journal Article |
2019 | Vorrichtung zum Beleuchten von Suspensionszellkulturen Rasche, Stefan; Schubert, Max; Beuel, Ann-Katrin | Patent |
2019 | Zafirlukast Is a Dual Modulator of Human Soluble Epoxide Hydrolase and Peroxisome Proliferator-Activated Receptor γ Göbel, T.; Diehl, O.; Heering, J.; Merk, D.; Angioni, C.; Wittmann, S.K.; Buscato, E. la; Kottke, R.; Weizel, L.; Schader, T.; Maier, T.J.; Geisslinger, G.; Schubert-Zsilavecz, M.; Steinhilber, D.; Proschak, E.; Kahnt, A.S. | Journal Article |
2018 | 20-HETE promotes glucose-stimulated insulin secretion in an autocrine manner through FFAR1 Tunaru, S.; Bonnavion, R.; Brandenburger, I.; Preussner, J.; Thomas, D.; Scholich, K.; Offermanns, S. | Journal Article |
2018 | 8-Methoxypsoralen Plus Ultraviolet A Reduces the Psoriatic Response to Imiquimod in a Murine Model Shirsath, N.; Wagner, K.; Tangermann, S.; Schlederer, M.; Ringel, C.; Kenner, L.; Brüne, B.; Wolf, P. | Journal Article |
2018 | Abatacept used in combination with non-methotrexate disease-modifying antirheumatic drugs Alten, R.; Burkhardt, H.; Feist, E.; Krüger, K.; Rech, J.; Rubbert-Roth, A.; Voll, R.E.; Elbez, Y.; Rauch, C. | Journal Article |
2018 | Achieving adequate protection and suitable food safety indicators Pucher, J.; Schlechtriem, Christian | Book Article |
2018 | Activation of Adenylyl Cyclase Causes Stimulation of Adenosine Receptors Pleli, T.; Mondorf, A.; Ferreiros, N.; Thomas, D.; Dvorak, K.; Biondi, R.M.; Heringdorf, D.M.; Zeuzem, S.; Geisslinger, G.; Zimmermann, H.; Waidmann, O.; Piiper, A. | Journal Article |
2018 | Advances and Challenges in Drug Design of PPARδ Ligands Maltarollo, V.G.; Kronenberger, T.; Windshugel, B.; Wrenger, C.; Goulart Trossini, G.H.; Honorio, K.M. | Journal Article |
2018 | Advances in the development of procedures to establish the toxicity of non-extractable residues (NER) in soil. LRI-ECO25 Harmsen, Joop; Hennecke, Dieter; Hund-Rinke, Kerstin; Lahr, Joost; Deneer, John | Report |
2018 | AICAR inhibits NFκB DNA binding independently of AMPK to attenuate LPS-triggered inflammatory responses in human macrophages Kirchner, J.; Brüne, B.; Namgaladze, D. | Journal Article |
2018 | Analysis and Optimization of Ecotoxicological Models under Uncertainty Klein, Judith : Schultz, Rüdiger; Escudero, Laureano F.; Schäfers, Christoph | Dissertation |
2018 | Analysis of the Genome and Metabolome of Marine Myxobacteria Reveals High Potential for Biosynthesis of Novel Specialized Metabolites Amiri Moghaddam, J.; Crüsemann, M.; Alanjary, M.; Harms, H.; Dávila-Céspedes, A.; Blom, J.; Poehlein, A.; Ziemert, N.; König, G.M.; Schäberle, T.F. | Journal Article |
2018 | Anti-inflammatory nitro-fatty acids suppress tumor growth by triggering mitochondrial dysfunction and activation of the intrinsic apoptotic pathway in colorectal cancer cells Kühn, B.; Brat, C.; Fettel, J.; Hellmuth, N.; Maucher, I.V.; Bulut, I.; Hock, K.J.; Grimmer, J.; Manolikakes, G.; Rühl, M.; Kühn, A.; Zacharowski, K.; Matrone, C.; Urbschat, A.; Roos, J.; Steinhilber, D.; Maier, T.J. | Journal Article |
2018 | Antiplasmodial activity of tick defensins in a mouse model of malaria Couto, J.; Tonk, M.; Ferrolho, J.; Antunes, S.; Vilcinskas, A.; Fuente, J. de la; Domingos, A.; Cabezas-Cruz, A. | Journal Article |
2018 | Apoptotic Cancer Cells Suppress 5-Lipoxygenase in Tumor-Associated Macrophages Ringleb, J.; Strack, E.; Angioni, C.; Geisslinger, G.; Steinhilber, D.; Weigert, A.; Brüne, B. | Journal Article |
2018 | Approaches to increase mechanistic understanding and aid in the selection of precipitation inhibitors for supersaturating formulations Price, D.J.; Ditzinger, F.; Koehl, N.J.; Jankovic, S.; Tsakiridou, G.; Nair, A.; Holm, R.; Kuentz, M.; Dressman, J.; Saal, C. | Journal Article |
2018 | Are elevated serum haemolysis markers a harbinger of adverse events in HeartMate II patients? Zayat, R.; Shoaib, M.; Khattab, M.A.; Ahmad, U.; Goetzenich, A.; Stoppe, C.; Foldenauer, A.C.; Moza, A.; Schnoering, H.; Autschbach, R.; Tewarie, L. | Journal Article |
2018 | Artificial neural network-assisted spectrophotometric method for monitoring fructo-oligosaccharides production Erdős, B.; Grachten, M.; Czermak, P.; Kovács, Z. | Journal Article |
2018 | Aryl thiosemicarbazones for the treatment of trypanosomatidic infections Linciano, P.; Moraes, C.B.; Alcantara, L.M.; Franco, C.H.; Pascoalino, B.; Freitas-Junior, L.H.; Macedo, S.; Santarem, N.; Cordeiro-da-Silva, A.; Gul, S.; Witt, G.; Kuzikov, M.; Ellinger, B.; Ferrari, S.; Luciani, R.; Quotadamo, A.; Costantino, L.; Costi, M.P. | Journal Article |
2018 | Aspergillus-specific antibodies: Targets and applications Schubert, M.; Spiegel, H.; Schillberg, S.; Nölke, G. | Journal Article |
2018 | Assessment of seafood contamination under the marine strategy framework directive: Contributions of the German environmental specimen bank Fliedner, Annette; Rüdel, Heinz; Knopf, Burkhard; Lohmann, Nina; Paulus, Martin; Jud, Michael; Pirntke, Ulrike; Koschorreck, Jan | Journal Article |
2018 | Associated risk factors influencing ovine Eimeria infections in southern Spain Carrau, T.; Silva, L.M.R.; Pérez, D.; Failing, K.; Martinez-Carrasco, C.; Macias, J.; Taubert, A.; Hermosilla, C.; Ruiz de Ybáñeze, R. | Journal Article |
2018 | Astrocytic ATX fuels synaptic phospholipid signaling involved in psychiatric disorders Thalman, C.; Horta, G.; Qiao, L.; Endle, H.; Tegeder, I.; Cheng, H.; Laube, G.; Sigrudsson, T.; Hauser, M.J.; Tenzer, S.; Distler, U.; Aoki, J.; Morris, A.J.; Geisslinger, G.; Röper, J.; Kirischuk, S.; Luhmann, H.J.; Radyushkin, K.; Nitsch, R.; Vogt, J. | Journal Article |
2018 | Astrocytic ATX fuels synaptic phospholipid signaling involved in psychiatric disorders Thalman, C.; Horta, G.; Qiao, L.; Endle, H.; Tegeder, I.; Cheng, H.; Laube, G.; Sigrudsson, T.; Hauser, M.J.; Tenzer, S.; Distler, U.; Aoki, J.; Morris, A.J.; Geisslinger, G.; Röper, J.; Kirischuk, S.; Luhmann, H.J.; Radyushkin, K.; Nitsch, R.; Vogt, J. | Journal Article |
2018 | Biomarker und Bildgebung zur Diagnose und Stratifizierung der rheumatoiden Arthritis und Spondylarthritis im BMBF-Verbund ArthroMark Häupl, T.; Skapenko, A.; Hoppe, B.; Skriner, K.; Burkhardt, H.; Poddubnyy, D.; Ohrndorf, S.; Sewerin, P.; Mansmann, U.; Stuhlmüller, B.; Schulze-Koops, H.; Burmester, G.-R. | Journal Article |
2018 | Biomarker und Bildgebung zur Diagnose und Stratifizierung der rheumatoiden Arthritis und Spondylarthritis im BMBF-Verbund ArthroMark Häupl, T.; Skapenko, A.; Hoppe, B.; Skriner, K.; Burkhardt, H.; Poddubnyy, D.; Ohrndorf, S.; Sewerin, P.; Mansmann, U.; Stuhlmüller, B.; Schulze-Koops, H.; Burmester, G.-R. | Journal Article |
2018 | Bioreactor-based production of glycoproteins in plant cell suspension cultures Holland, T.; Buyel, J.F. | Book Article |
2018 | Biota monitoring under the Water Framework Directive: On tissue choice and fish species selection Fliedner, Annette; Rüdel, Heinz; Lohmann, Nina; Buchmeier, Georgia; Koschorreck, Jan | Journal Article |
2018 | Boosting Anti-Inflammatory Potency of Zafirlukast by Designed Polypharmacology Schierle, S.; Flauaus, C.; Heitel, P.; Willems, S.; Schmidt, J.; Kaiser, A.; Weizel, L.; Goebel, T.; Kahnt, A.S.; Geisslinger, G.; Steinhilber, D.; Wurglics, M.; Rovati, G.E.; Schmidtko, A.; Proschak, E.; Merk, D. | Journal Article |
2018 | Bovine embryo elongation is altered due to maternal fatty acid supplementation Giller, K.; Drews, B.; Berard, J.; Kienberger, H.; Schmicke, M.; Frank, J.; Spanier, B.; Daniel, H.; Geisslinger, G.; Ulbrich, S.E. | Journal Article |
2018 | C5aR activation in the absence of C5a Syed, S.N.; Rau, E.; Ziegelmann, M.; Sogkas, G.; Brüne, B.; Schmidt, R.E. | Journal Article |
2018 | Carborane‐Based Analogues of 5‐Lipoxygenase Inhibitors Co‐inhibit Heat Shock Protein 90 in HCT116 Cells Kuhnert, R.; Sárosi, M.-B.; George, S.; Lönnecke, P.; Hofmann, B.; Steinhilber, D.; Steinmann, S.; Schneider‐Stock, R.; Murganić, B.; Mijatović, S.; Maksimović‐Ivanić, D.; Hey-Hawkins, E. | Journal Article |
2018 | Cationic polyacrylamide copolymers (PAMs): Environmental half life determination in sludge‑treated soil Hennecke, Dieter; Bauer, Angela; Herrchen, Monika; Wischerhoff, Erik; Gores, Friedhelm | Journal Article |
2018 | Cell adhesion-induced transient interaction of ADAM15 with poly(A) binding protein at the cell membrane colocalizes with mRNA translation Böhm, B.B.; Fehrl, Y.; Janczi, T.; Schneider, N.; Burkhardt, H. | Journal Article |
2018 | Cell-free protein synthesis system Buntru, Matthias; Schillberg, Stefan; Vogel, Simon | Patent |
2018 | Challenges in the Development of a Thiol-Based Broad-Spectrum Inhibitor for Metallo-β-Lactamases Büttner, D.; Kramer, J.S.; Klingler, F.-M.; Wittmann, S.K.; Hartmann, M.R.; Kurz, C.G.; Kohnhäuser, D.; Weizel, L.; Brüggerhoff, A.; Frank, D.; Steinhilber, D.; Wichelhaus, T.A.; Pogoryelov, D.; Proschak, E. | Journal Article |
2018 | Characterization of interleukin-6 monoclonal antibodies for future applications Chouman, K. | Dissertation |
2018 | Characterization of new anti-IL-6 antibodies revealed high potency candidates for intracellular cytokine detection and specific targeting of IL-6 receptor binding sites Chouman, Karinna; Korioth-Schmitz, Birgit; Sack, Markus; Engelbert Schmitz, Jörn; Tuan Pham, Anh; Fischer, Rainer; Barth, Stefan; Klockenbring, Torsten; Fendel, Rolf | Journal Article |
2018 | Charakterisierung und zelluläre Lokalisation der humanen 5-Lipoxygenase und deren Isoformen 5-LO∆13, 5-LO∆4 und 5-LOp12 Ball, A.-K. | Dissertation |
2018 | Chemosensitivity of human colon cancer cells is influenced by a p53-dependent enhancement of ceramide synthase 5 and induction of autophagy Brachtendorf, S.; Wanger, R.A.; Birod, K.; Thomas, D.; Trautmann, S.; Wegner, M.-S.; Fuhrmann, D.C.; Brüne, B.; Geisslinger, G.; Grösch, S. | Journal Article |
2018 | Combined Proteomic and In Silico Target Identification Reveal a Role for 5-Lipoxygenase in Developmental Signaling Pathways Brand, S.; Roy, S.; Schröder, P.; Rathmer, B.; Roos, J.; Kapoor, S.; Patil, S.; Pommerenke, C.; Maier, T.; Janning, P.; Eberth, S.; Steinhilber, D.; Schade, D.; Schneider, G.; Kumar, K.; Ziegler, S.; Waldmann, H. | Journal Article |
2018 | Comparative analysis of the transcriptome responses of zebrafish embryos after exposure to low concentrations of cadmium, cobalt and copper Sonnack, Laura; Klawonn, Thorsten; Kriehuber, Ralf; Hollert, Henner; Schäfers, Christoph; Fenske, Martina | Journal Article |
2018 | Comparative estrogenicity of endogenous, environmental and dietary estrogens in pregnant women I Fleck, S.C.; Twaddle, N.C.; Churchwell, M.I.; Doerge, D.R.; Pande, P.; Teeguarden, J.G. | Journal Article |
2018 | A comparison of two biorelevant in vitro drug release methods for nanotherapeutics based on advanced physiologically-based pharmacokinetic modelling Jung, F.; Nothnagel, L.; Gao, F.; Thurn, M.; Vogel, V.; Wacker, M.G. | Journal Article |
2018 | Computational functional genomics-based approaches in analgesic drug discovery and repurposing Lippmann, C.; Kringel, D.; Ultsch, A.; Lötsch, J. | Journal Article |
2018 | A coupled fluorescence-based assay for the detection of protein arginine N-methyltransferase 6 (PRMT6) enzymatic activity Kramer, J.; Désor, V.; Brunst, S.; Wittmann, S.K.; Lausen, J.; Heering, J.; Proschak, A.; Proschak, E. | Journal Article |
2018 | Current evidence of cannabinoid-based analgesia obtained in preclinical and human experimental settings Lötsch, J.; Weyer-Menkhoff, I.; Tegeder, I. | Journal Article |
2018 | Current status and perspectives of the molecular farming landscape Spiegel, H.; Stöger, E.; Twyman, R.M.; Buyel, J.F. | Book Article |
2018 | Decreasing δ13C and δ15N values in four coastal species at different trophic levels indicate a fundamental food-web shift in the southern North and Baltic Seas between 1988 and 2016 Corman, Anna-Marie; Schwemmer, Philipp; Mercker, Moritz; Asmus, Harald; Rüdel, Heinz; Klein, Roland; Boner, Markus; Hofem, Sabine; Koschorreck, Jan; Garthe, Stefan | Journal Article |
2018 | Development of a Focused Library of Triazole‐Linked Privileged‐Structure‐Based Conjugates Leading to the Discovery of Novel Phenotypic Hits against Protozoan Parasitic Infections Uliassi, E.; Piazzi, L.; Belluti, F.; Mazzanti, A.; Kaiser, M.; Brun, R.; Moraes, C.B.; Freitas-Junior, L.H.; Gul, S.; Kuzikov, M.; Ellinger, B.; Borsari, C.; Costi, M.P.; Bolognesi, M.L. | Journal Article |
2018 | Development of an AmpliSeqTM Panel for Next-Generation Sequencing of a Set of Genetic Predictors of Persisting Pain Kringel, D.; Kaunisto, M.A.; Lippmann, C.; Kalso, E.; Lötsch, J. | Journal Article |
2018 | Development, current applications and future roles of biorelevant two‐stage in vitro testing in drug development Fiolka, T.; Dressman, J. | Journal Article |
2018 | Dielectric Spectroscopy and Optical Density Measurement for the Online Monitoring and Control of Recombinant Protein Production in Stably Transformed Drosophila melanogaster S2 Cells Zitzmann, J.; Weidner, T.; Eichner, G.; Salzig, D.; Czermak, P. | Journal Article |
2018 | Dietary phytol reduces clinical symptoms in experimental autoimmune encephalomyelitis (EAE) at least partially by modulating NOX2 expression Blum, L.; Tafferner, N.; Spring, I.; Kurz, J.; deBruin, N.; Geisslinger, G.; Parnham, M.J.; Schiffmann, S. | Journal Article |
2018 | Differentiation of human iPSCs into VSMCs and generation of VSMC-derived calcifying vascular cells Trillhaase, A.; Haferkamp, U.; Rangnau, A.; Märtens, M.; Schmidt, B.; Trilck, M.; Seibler, P.; Aherrahrou, R.; Erdmann, J.; Aherrahrou, Z. | Journal Article |
2018 | Dimerization quality control via ubiquitylation Herhaus, L.; Dikic, I. | Journal Article |
2018 | Discovery of polar spirocyclic orally bioavailable urea inhibitors of soluble epoxide hydrolase Lukin, A.; Kramer, J.; Hartmann, M.; Weizel, L.; Hernandez-Olmos, V.; Falahati, K.; Burghardt, I.; Kalinchenkova, N.; Bagnyukova, D.; Zhurilo, N.; Rautio, J.; Forsberg, M.; Ihalainen, J.; Auriola, S.; Leppänen, J.; Konstantinov, I.; Pogoryelov, D.; Proschak, E.; Dar'in, D.; Krasavin, M. | Journal Article |
2018 | Downregulation of BTLA on NKT Cells Promotes Tumor Immune Control in a Mouse Model of Mammary Carcinoma Sekar, D.; Govene, L.; Del Río, M.-L.; Sirait-Fischer, E.; Fink, A.F.; Brüne, B.; Rodriguez-Barbosa, J.I.; Weigert, A. | Journal Article |
2018 | Downstream processing of a plant-derived malaria transmission-blocking vaccine candidate Menzel, S.; Holland, T.; Boes, A.; Spiegel, H.; Fischer, R.; Buyel, J.F. | Journal Article |
2018 | Drug-Mediated Intracellular Donation of Nitric Oxide Potently Inhibits 5-Lipoxygenase Roos, J.; Peters, M.; Maucher, I.V.; Kühn, B.; Fettel, J.; Hellmuth, N.; Brat, C.; Sommer, B.; Urbschat, A.; Piesche, M.; Vogel, A.; Proschak, E.; Blöcher, R.; Buscató, E.; Häfner, A.-K.; Matrone, C.; Werz, O.; Heidler, J.; Wittig, I.; Angioni, C.; Geisslinger, G.; Parnham, M.J.; Zacharowski, K.; Steinhilber, D.; Maier, T.J. | Journal Article |
2018 | Efficacy and safety of tregalizumab in patients with rheumatoid arthritis and an inadequate response to methotrexate Vollenhoven, R.F. van; Keystone, E.C.; Strand, V.; Pacheco-Tena, C.; Vencovský, J.; Behrens, F.; Racewicz, A.; Zipp, D.; Rharbaoui, F.; Wolter, R.; Knierim, L.; Schmeidl, R.; Zhou, X.; Aigner, S.; Dälken, B.; Wartenberg-Demand, A. | Journal Article |
2018 | Elimination of different leukaemia subtypes using novel CD89-specific human cytolytic fusion proteins Gresch, G.; Schenke, L.; Mladenov, R.; Zwirner, S.; Cremer, C.; Niesen, J.; Grieger, E.; Brümmendorf, T.; Jost, E.; Fischer, R.; Stockmeyer, B.; Barth, S.; Nachreiner, T.; Stein, C. | Journal Article |
2018 | Elusive mitochondrial connection to inflammation uncovered Stolz, A.; Dikic, I. | Journal Article |
2018 | Empfehlung zur Einrichtung eines nationalen Observatorien-Netzes für die terrestrische Ökosystemforschung Kögel-Knabner, Ingrid; Teutsch, Georg; Adrian, Rita; Blanckenburg, Friedhelm von; Flügge, Ulf-Ingo; Kolle, Olaf; Kleinn, Christoph; Küsel, Kirsten; Lischeid, Gunnar; Löw, Alexander; Schäfers, Christoph; Schmid, Hans Peter; Simmer, Clemens; Vereecken, Harry; Walz, Rainer | Report |
2018 | Enhanced applications of the zebrafish (Danio rerio) embryo toxicity test as a model to mechanistically differentiate metal toxicity effects in fish Sonnack, Laura : Hollert, Henner; Schäffer, Andreas; Muth-Köhne, Elke | Dissertation |
2018 | Enrichment of vitamin D2 in mycelium from submerged cultures of the agaric mushroom Pleurotus sapidus Ahlborn, J.; Calzolari, N.; Spielmeyer, A.; Avci, S.S.; Zimmer, M.; Rühl, M. | Journal Article |
2018 | Environmental impacts by fragments released from nanoenabled products: A multiassay, multimaterial exploration by the SUN approach Amorim, Monica J.B.; Lin, Sijie; Schlich, Karsten; Navas, Jose Maria; Brunelli, Andrea; Neubauer, Nicole; Vilsmeier, Klaus; Costa, Anna L.; Gondikas, Andreas; Xia, Tian; Galbis, Liliana; Badetti, Elena; Marcomini, Antonio; Hristozov, Danail; Kammer, Frank von der; Hund-Rinke, Kerstin; Scott-Fordsmand, Janeck J.; Nel, André; Wohlleben, Wendel | Journal Article |
2018 | Enzyme membrane reactor system (EMRS) for the bioconversion of lignin-containing substrates by a novel heme peroxidase Busse, N. | Dissertation |
2018 | The European Marine Biological Research Infrastructure Cluster: An Alliance of European Research Infrastructures to Promote the Blue Bioeconomy Piña, M.; Colas, P.; Cancio, I.; Audic, A.; Bosser, L.; Canario, A.; Gribbon, P.; Johnston, I.A.; Kervella, A.E.; Kooistra, W.H.C.F.; Merciecca, M.; Magoulas, A.; Nardello, I.; Smith, D.; Pade, N.; Robinson, D.; Schön, A.; Schultz, F.; Kloareg, B. | Book Article |
2018 | Expression and purification of human phosphatase and actin regulator 1 (PHACTR1) in plant-based systems Gengenbach, B.B.; Müschen, C.R.; Buyel, J.F. | Journal Article |
2018 | Fishing for contaminants Hausen, J.; Otte, J.C.; Legradi, J.; Yang, L.; Strähle, U.; Fenske, M.; Hecker, M.; Tang, S.; Hammers-Wirtz, M.; Hollert, H.; Keiter, S.H.; Ottermanns, R. | Journal Article |
2018 | Fitness costs of infection with Serratia symbiotica are associated with greater susceptibility to insecticides in the pea aphid Acyrthosiphon pisum Skaljac, M.; Kirfel, P.; Grotmann, J.; Vilcinskas, A. | Journal Article |
2018 | Four chemical trends will shape the next decade's directions in perfluoroalkyl and polyfluoroalkyl substances research Kotthoff, Matthias; Bücking, Mark | Journal Article |
2018 | Fraunhofer-Institut für Molekularbiologie und Angewandte Oekologie. Jahresbericht 2017/2018 | Annual Report |
2018 | Freisetzung von Silberionen aus Silber-Nanopartikeln und deren Verteilung in modellierten Gewässersystemen Wasmuth, C. | Journal Article |
2018 | A freshwater mesocosm study into the effects of the neonicotinoid insecticide thiamethoxam at multiple trophic levels Finnegan, Meaghean C.; Emburey, Simon; Hommen, Udo; Baxter, Leilan R.; Hoekstra, Paul F.; Hanson, Mark L.; Thompson, Helen; Hamer, Mick | Journal Article |
2018 | The FT/FD-dependent initiation of flowering under long-day conditions in the day-neutral species Nicotiana tabacum originates from the facultative short-day ancestor Nicotiana tomentosiformis Beinecke, F.A.; Grundmann, L.; Wiedmann, D.R.; Schmidt, F.J.; Caesar, A.S.; Zimmermann, M.; Lahme, M.; Twyman, R.M.; Prüfer, D.; Noll, G.A. | Journal Article |
2018 | Functional characterization of squalene synthase and squalene epoxidase in Taraxacum koksaghyz Unland, K.; Pütter, K.M.; Vorwerk, K.; Deenen, N. van; Twyman, R.M.; Prüfer, D.; Schulze Gronover, C. | Journal Article |
2018 | Functional exploration of natural networks and ecological communities Ankenbrand, M.J.; Hohlfeld, S.C.Y.; Weber, L.; Förster, F.; Keller, A. | Journal Article |
2018 | The G2A Receptor Controls Polarization of Macrophage by Determining Their Localization Within the Inflamed Tissue Kern, K.; Schäfer, S.M.G; Cohnen, J.; Pierre, S.; Osthues, T.; Tarighi, N.; Hohmann, S.; Ferreiros, N.; Brüne, B.; Weigert, A.; Geisslinger, G.; Sisignano, M.; Scholich, K. | Journal Article |
2018 | Gene silencing in Tribolium castaneum as a tool for the targeted identification of candidate RNAi targets in crop pests Knorr, E.; Fishilevich, E.; Tenbusch, L.; Frey, M.L.F.; Rangasamy, M.; Billion, A.; Worden, S.E.; Gandra, P.; Arora, K.; Lo, W.; Schulenberg, G.; Valverde-Garcia, P.; Vilcinskas, A.; Narva, K.E. | Journal Article |
2018 | Generation of two human isogenic iPSC lines from fetal dermal fibroblasts Tandon, R.; Brändl, B.; Baryshnikova, N.; Landshammer, A.; Steenpaß, L.; Keminer, O.; Pless, O.; Müller, F.-J. | Journal Article |
2018 | Generierung und Charakterisierung rekombinanter single chain Fv-Derivate für therapeutische und diagnostische Anwendungen an unterschiedlichen Leukämie Subtypen Gresch, G. | Dissertation |
2018 | The genome sequence of the commercially cultivated mushroom Agrocybe aegerita reveals a conserved repertoire of fruiting-related genes and a versatile suite of biopolymer-degrading enzymes Gupta, D.K.; Rühl, M.; Mishra, B.; Kleofas, V.; Hofrichter, M.; Herzog, R.; Pecyna, M.J.; Sharma, R.; Kellner, H.; Hennicke, F.; Thines, M. | Journal Article |
2018 | Grouping concept for metal and metal oxide nanomaterials with regard to their ecotoxicological effects on algae, daphnids and fish embryos Hund-Rinke, K.; Schlich, Karsten; Kühnel, Dana; Hellack, Bryan; Kaminski, Heinz; Nickel, Carmen | Journal Article |
2018 | Halogenated flame retardants in tree samples applied as bioindicators for atmospheric pollution Dreyer, Annekatrin; Neugebauer, Frank; Rüdel, Heinz; Klein, Roland; Lohmann, Nina; Rauert, Caren; Koschorreck, Jan | Journal Article |
2018 | Heterotypic Ubiquitin Chains: Seeing is Believing Stolz, A.; Dikic, I. | Journal Article |
2018 | High cell density cultivation of Δgor/ΔtrxB E. coli in a chemically defined minimal medium with an enhanced iron concentration Joachim, M.; Schäfer, J.G.; Gerlach, D.; Czermak, P. | Journal Article |
2018 | High titer oncolytic measles virus production process by integration of dielectric spectroscopy as online monitoring system Grein, T.A.; Loewe, D.; Dieken, H.; Salzig, D.; Weidner, T.; Czermak, P. | Journal Article |
2018 | High-sensitive troponin is associated with subclinical imaging biosignature of inflammatory cardiovascular involvement in systemic lupus erythematosus Winau, L.; Baydes, R.H.; Braner, A.; Drott, U.; Burkhardt, H.; Sangle, S.; D'Cruz, D.P.; Carr-White, G.; Marber, M.; Schnoes, K.; Arendt, C.; Klingel, K.; Vogl, T.J.; Zeiher, A.M.; Nagel, E.; Puntmann, V.O. | Journal Article |
2018 | Highly efficient genome editing by homology-directed repair using Cas9 protein in Ceratitis capitata Aumann, R.A.; Schetelig, M.F.; Häcker, I. | Journal Article |
2018 | Highly Potent 17β-HSD2 Inhibitors with a Promising Pharmacokinetic Profile for Targeted Osteoporosis Therapy Siebenbuerger, L.; Hernandez-Olmos, V.; Abdelsamie, A.S.; Frotscher, M.; Koppen, C.J. van; Marchais-Oberwinkler, S.; Scheuer, C.; Laschke, M.W.; Menger, M.D.; Boerger, C.; Hartmann, R.W. | Journal Article |
2018 | The histone demethylase Jarid1b mediates angiotensin II‐induced endothelial dysfunction by controlling the 3'UTR of soluble epoxide hydrolase Vasconez, A.E.; Janetzko, P.; Oo, J.A.; Pflüger‐Müller, B.; Ratiu, C.; Gu, L.; Helin, K.; Geisslinger, G.; Fleming, I.; Schröder, K.; Fork, C.; Brandes, R.P.; Leisegang, M.S. | Journal Article |
2018 | How to effectively treat acute leukemia patients bearing MLL-rearrangements? Steinhilber, D.; Marschalek, R. | Journal Article |
2018 | How to measure release from nanosized carriers? Nothnagel, L.; Wacker, M.G. | Journal Article |
2018 | Human pharmacological approaches to TRP-ion-channel-based analgesic drug development Weyer-Menkhoff, I.; Lötsch, J. | Journal Article |
2018 | Identification and characterization of natural viruses associated with the invasive insect pest Drosophila suzukii Carrau, T.; Hiebert, N.; Vilcinskas, A.; Lee, K.-Z. | Journal Article |
2018 | Identification of approved drugs as potent inhibitors of pregnane X receptor activation with differential receptor interaction profiles Burk, O.; Kuzikov, M.; Kronenberger, T.; Jeske, J.; Keminer, O.; Thasler, W.E.; Schwab, M.; Wrenger, C.; Windshügel, B. | Journal Article |
2018 | Identification of disease-distinct complex biomarker patterns by means of unsupervised machine-learning using an interactive R toolbox (Umatrix) Lötsch, J.; Lerch, F.; Djaldetti, R.; Tegder, I.; Ultsch, A. | Journal Article |
2018 | Immunological larval polyphenism in the map butterfly Araschnia levana reveals the photoperiodic modulation of immunity Baudach, A.; Lee, K.-Z.; Vogel, H.; Vilcinskas, A. | Journal Article |
2018 | Immunomodulation by antibiotics Blum, L.; Schiffmann, S.; Parnham, M.J. | Book Article |
2018 | The impact of food intake on the luminal environment and performance of oral drug products with a view to in vitro and in silico simulations: a PEARRL review Pentafragka, C.; Symillides, M.; McAllister, M.; Dressman, J.; Vertzoni, M.; Reppas, C. | Journal Article |
2018 | An in silico approach to determine challenges in the bioavailability of ciprofloxacin, a poorly soluble weak base with borderline solubility and permeability characteristics Hansmann, S.; Miyaji, Y.; Dressman, J. | Journal Article |
2018 | In vitro and in silico analysis of the effects of D2 receptor antagonist target binding kinetics on the cellular response to fluctuating dopamine concentrations Witte, W.E.A. de; Versfelt, J.W.; Kuzikov, M.; Rolland, S.; Georgi, V.; Gribbon, P.; Gul, S.; Huntjens, D.; Graaf, P.H. van der; Danhof, M.; Fernández‐Montalván, A.; Witt, G.; Lange, E.C.M. de | Journal Article |
2018 | In vitro methods to assess drug precipitation in the fasted small intestine O'Dwyer, P.J.; Litou, C.; Box, K.J.; Dressman, J.; Kostewicz, E.S.; Kuentz, M.; Reppas, C. | Journal Article |
2018 | An in vitro test system for compounds that modulate human inflammatory macrophage polarization Shiratori, H.; Feinweber, C.; Luckhardt, S.; Wallner, N.; Geisslinger, G.; Weigert, A.; Parnham, M.J. | Journal Article |
2018 | Inactivation kinetics of Escherichia Coli and Staphylococcus Aureus by a hydrogen peroxide based disinfectant Grigoryan, K.; Badalyan, G.; Nersisyan, L.; Tavadyan, L.; Sargsyan, M. | Journal Article |
2018 | The infection of Harmonia axyridis by a parasitic nematode is mediated by entomopathogenic bacteria and triggers sex-specific host immune responses Gegner, T.; Carrau, T.; Vilcinskas, A.; Lee, K.Z. | Journal Article |
2018 | Inhibition of 53BP1 favors homology-dependent DNA repair and increases CRISPR-Cas9 genome-editing efficiency Canny, M.D.; Moatti, N.; Wan, L.C.K.; Fradet-Turcotte, A.; Krasner, D.; Mateos-Gomez, P.A.; Zimmermann, M.; Orthwein, A.; Juang, Y.-C.; Zhang, W.; Noordermeer, S.M.; Seclen, E.; Wilson, M.D.; Vorobyov, A.; Munro, M.; Ernst, A.; Ng, T.F.; Cho, T.; Cannon, P.M.; Sidhu, S.S.; Sicheri, F.; Durocher, D. | Journal Article |
2018 | Inhibitors of IL-38 for use in treating and/or preventing cancer in a subject Brüne, Bernhard; Ernst, Andreas; Mora, Javier; Parnham, Michael John; Putyrski, Mateusz | Patent |
2018 | Insights into catalysis and function of phosphoribosyl-linked serine ubiquitination Kalayil, S.; Bhogaraju, S.; Bonn, F.; Shin, D.; Liu, Y.; Gan, N.; Basquin, J.; Grumati, P.; Luo, Z.-Q.; Dikic, I. | Journal Article |
2018 | Ixekizumab is efficacious when used alone or when added to conventional synthetic disease-modifying antirheumatic drugs (cDMARDs) in patients with active psoriatic arthritis and previous inadequate response or intolerance to tumour necrosis factor inhibitors Nash, P.; Behrens, F.; Orbai, A.-M.; Rathmann, S.S.; Adams, D.H.; Benichou, O.; Deodhar, A. | Journal Article |
2018 | Kinetics and modeling of cell growth for potential anthocyanin induction in cultures of Taraxacum officinale G.H. Weber ex Wiggers (Dandelion) in vitro Martínez, M.E.; Poirrier, P.; Prüfer, D.; Schulze Gronover, C.; Jorquera, L.; Ferrer, P.; Díaz, K.; Chamy, R. | Journal Article |
2018 | Knotting nets. Molecular junctions of interconnecting endocrine axes identified by application of the adverse outcome pathway (AOP) concept Brüggemann, Maria; Licht, Oliver; Fetter, Éva; Teigeler, Matthias; Schäfers, Christoph; Eilebrecht, Elke | Journal Article |
2018 | Laccase production and pellet morphology of Coprinopsis cinerea transformants in liquid shake flask cultures Rühl, M.; Lange, K.; Kües, U. | Journal Article |
2018 | The levels of peroxisomal catalase protein and activity modulate the onset of cell death in tobacco BY-2 cells via reactive oxygen species levels and autophagy Tyutereva, Elena V.; Dobryakova, Ksenia S.; Schiermeyer, Andreas; Shishova, Maria F.; Pawlowski, Katharina; Demidchik, Vadim; Reumann, Sigrun; Voitsekhovskaja, Olga V. | Journal Article |
2018 | A linear epitope coupled to DsRed provides an affinity ligand for the capture of monoclonal antibodies Rühl, C.; Knödler, M.; Opdensteinen, P.; Buyel, J.F. | Journal Article |
2018 | Long-term effects of three different silver sulfide nanomaterials, silver nitrate and bulk silver sulfide on soil microorganisms and plants Schlich, Karsten; Hoppe, Martin; Kraas, Marco; Schubert, Jonas; Chanana, Munish; Hund-Rinke, Kerstin | Journal Article |
2018 | Low protease content in Medicago truncatula cell cultures facilitates recombinant protein production Santos, Rita B.; Chandrasekar, Balakumaran; Mandal, Manoj K.; Kaschani, Farnush; Kaiser, Markus; Both, Leonard; Hoorn, Renier A.L. van der; Schiermeyer, Andreas; Abranches, Rita | Journal Article |
2018 | Machine learning in pain research Lötsch, J.; Ultsch, A. | Journal Article |
2018 | A machine-learned analysis of human gene polymorphisms modulating persisting pain points to major roles of neuroimmune processes Kringel, D.; Lippmann, C.; Parnham, M.J.; Kalso, E.; Ultsch, A.; Lötsch, J. | Journal Article |
2018 | Machine-learned analysis of quantitative sensory testing responses to noxious cold stimulation in healthy subjects Weyer-Menkhoff, I.; Thrun, M.C.; Lötsch, J. | Journal Article |
2018 | Machine-learned analysis of the association of next-generation sequencing-based human TRPV1 and TRPA1 genotypes with the sensitivity to heat stimuli and topically applied capsaicin Kringel, D.; Geisslinger, G.; Resch, E.; Oertel, B.G.; Thrun, M.C.; Heinemann, S.; Lötsch, J. | Journal Article |
2018 | Machine-learned selection of psychological questionnaire items relevant to the development of persistent pain after breast cancer surgery Lötsch, J.; Sipilä, R.; Dimova, V.; Kalso, E. | Journal Article |
2018 | Machine-learning based lipid mediator serum concentration patterns allow identification of multiple sclerosis patients with high accuracy Lötsch, J.; Schiffmann, S.; Schmitz, K.; Brunkhorst, R.; Lerch, F.; Ferreiros, N.; Wicker, S.; Tegeder, I.; Geisslinger, G.; Ultsch, A. | Journal Article |
2018 | Machine-learning-derived classifier predicts absence of persistent pain after breast cancer surgery with high accuracy Lötsch, J.; Sipilä, R.; Tasmuth, T.; Kringel, D.; Estlander, A.-M.; Meretoja, T.; Kalso, E.; Ultsch, A. | Journal Article |
2018 | Mannan-induced Nos2 in macrophages enhances IL-17–driven psoriatic arthritis by innate lymphocytes Zhong, J.; Scholz, T.; Yau, A.C.Y.; Guerard, S.; Hüffmeier, U.; Burkhardt, H.; Holmdahl, R. | Journal Article |
2018 | Manufacturing and Safety Guidelines for Manufactured Functionalized Nanomaterials in Pharmaceutics Wacker, M.G.; Janas, C.; Ferreira, F.S.; Vieira, F.P. | Book Article |
2018 | Marine Heterobranchia (Gastropoda, Mollusca) in Bunaken National Park, North Sulawesi, Indonesia Eisenbarth, J.-H.; Undap, N.; Papu, A.; Schillo, D.; Dialao, J.; Reumschüssel, S.; Kaligis, F.; Bara, R.; Schäberle, T.F.; König, G.M.; Yonow, N.; Wägele, H. | Journal Article |
2018 | Mast cell tetrahydrobiopterin contributes to itch in mice Zschiebsch, K.; Fischer, C.; Wilken‐Schmitz, A.; Geisslinger, G.; Channon, K.; Watschinger, K.; Tegeder, I. | Journal Article |
2018 | Mechanism and medical implications of mammalian autophagy Dikic, I.; Elazar, Z. | Journal Article |
2018 | Mechanistic Understanding of Enhanced Human Oral Bioavailability of Fenofibric Acid from Novel Lipid Carriers Using Semi- Physiologically Based Pharmacokinetic Model and Various Analytical Approaches Including Biorelevant Dissolution Testing Fei, Y. | Dissertation |
2018 | Metabolomic Profiles for Primary Progressive Multiple Sclerosis Stratification and Disease Course Monitoring Stoessel, D.; Stellmann, J.-P.; Willing, A.; Behrens, B.; Rosenkranz, S.C.; Hodecker, S.C.; Stürner, K.H.; Reinhardt, S.; Fleischer, S.; Deuschle, C.; Maetzler, W.; Berg, D.; Heesen, C.; Walther, D.; Schauer, N.; Friese, M.A.; Pless, O. | Journal Article |
2018 | Microbiome-assisted carrion preservation aids larval development in a burying beetle Shukla, S.P.; Plata, C.; Reichelt, M.; Steiger, S.; Heckel, D.G.; Kaltenpoth, M.; Vilcinskas, A.; Vogel, H. | Journal Article |
2018 | Mikro- und Nanoarzneiformen in Formulierung und Qualitätskontrolle. Teil 2 Nothnagel, L.; Wacker, M.G. | Journal Article |
2018 | Mikro-und Nanoarzneiformen in Formulierung und Qualitätskontrolle. Teil 2 Nothnagel, L.; Wacker, M.G. | Journal Article |
2018 | Minimal Disease Activity as a Treatment Target in Psoriatic Arthritis: A Review of the Literature Gossec, L.; McGonagle, D.; Korotaeva, T.; Lubrano, E.; Miguel, E. de; Østergaard, M.; Behrens, F. | Journal Article |
2018 | Minimal disease activity is a stable measure of therapeutic response in psoriatic arthritis patients receiving treatment with adalimumab Behrens, F.; Koehm, M.; Schwaneck, E.C.; Schmalzing, M.; Gnann, H.; Greger, G.; Tony, H.P.; Burkhardt, H. | Journal Article |
2018 | Mitochondrial fragmentation in human macrophages attenuates palmitate-induced inflammatory responses Zezina, E.; Snodgrass, R.G.; Schreiber, Y.; Zukunft, S.; Schürmann, C.; Meyer zu Heringdorff, D.; Geisslinger, G.; Fleming, I.; Brandes, R.P.; Brüne, B.; Namgaladze, D. | Journal Article |
2018 | Molecular techniques for the detection and identification of yeasts in wine Diaz, Cecilia; Badalyan, Grigori; Bücking, Mark | Book Article |
2018 | Molecular tools to create new strains for mosquito sexing and vector control Häcker, I.; Schetelig , M.F. | Journal Article |
2018 | Mutations in PMPCB Encoding the Catalytic Subunit of the Mitochondrial Presequence Protease Cause Neurodegeneration in Early Childhood Vögtle, F.-N.; Brändl, B.; Larson, A.; Pendziwiat, M.; Friederich, M.W.; White, S.M.; Basinger, A.; Kücükköse, C.; Muhle, H.; Jähn, J.A.; Keminer, O.; Helbig, K.L.; Delto, C.F.; Myketin, L.; Mossmann, D.; Burger, N.; Miyake, N.; Burnett, A.; Baalen, A. van; Lovell, M.A.; Matsumoto, N.; Walsh, M.; Yu, H.-C.; Shinde, D.N.; Stephani, U.; Hove, J.L.K. van; Müller, F.-J.; Helbig, I. | Journal Article |
2018 | Mutual inversion of flurbiprofen enantiomers in various rat and mouse strains Bruin, N. de; Ferreirós, N.; Schmidt, M.; Hofmann, M.; Angioni, C.; Geisslinger, G.; Parnham, M.J. | Journal Article |
2018 | Nanomaterials: Certain aspects of application, risk assessment and risk communication Laux, Peter; Tentschert, Jutta; Riebeling, Christian; Braeuning, Albert; Creutzenberg, Otto; Epp, Astrid; Fessard, Valérie; Haas, Karl-Heinz; Haase, Andrea; Hund-Rinke, Kerstin; Jakubowski, Norbert; Kearns, Peter; Lampen, Alfonso; Rauscher, Hubert; Schoonjans, Reinhilde; Störmer, Angela; Thielmann, Axel; Mühle, Uwe; Luch, Andreas | Journal Article |
2018 | Nanopharmaceuticals for wound healing Ashtikar, M.; Wacker, M.G. | Journal Article |
2018 | Non-invasive bioluminescence imaging as a standardized assessment measure in mouse models of dermal inflammation Hofmann, M.C.J.; Schmidt, M.; Arne, O.; Geisslinger, G.; Parnham, M.J.; Bruin, N.M.W.J. de | Journal Article |
2018 | Novel Biomarkers for diagnosis and progression of primary progressive multiple sclerosis (PPMS) Friese, Manuel; Pleß, Ole; Schauer, Nicolas; Stoessel, Daniel | Patent |
2018 | A Novel Function for 15-Lipoxygenases in Cholesterol Homeostasis and CCL17 Production in Human Macrophages Snodgrass, R.G.; Zezina, E.; Namgaladze, D.; Gupta, S.; Angioni, C.; Geisslinger, G.; Lütjohann, D.; Brüne, B. | Journal Article |
2018 | Novel sensor platform for rapid detection and quantification of coliforms on food contact surfaces Badalyan, Grigori; Diaz, Cecilia; Bücking, Mark; Lipski, André | Journal Article |
2018 | Nutritional immunology: Diversification and diet-dependent expression of antimicrobial peptides in the black soldier fly Hermetia illucens Vogel, H.; Müller, A.; Heckel, D.G.; Gutzeit, H.; Vilcinskas, A. | Journal Article |
2018 | On the relationship of anthranilic derivatives structure and the FXR (Farnesoid X receptor) agonist activity Kronenberger, T.; Windshügel, B.; Wrenger, C.; Honorio, K.M.; Maltarollo, V.G. | Journal Article |
2018 | Optimizing the composition of a synthetic cellulosome complex for the hydrolysis of softwood pulp Leis, B.; Held, C.; Andreeßen, B.; Liebl, W.; Graubner, S.; Schulte, L.-P.; Schwarz, W.H.; Zverlov, V.V. | Journal Article |
2018 | Oral plasma kallikrein inhibitor for prophylaxis in hereditary angioedema Aygören-Pürsün, E.; Bygum, A.; Grivcheva-Panovska, V.; Magerl, M.; Graff, J.; Steiner, U.C.; Fain, O.; Huissoon, A.; Kinaciyan, T.; Farkas, H.; Lleonart, R.; Longhurst, H.J.; Rae, W.; Triggiani, M.; Aberer, W.; Cancian, M.; Zanichelli, A.; Smith, W.B.; Baeza, M.L.; Du-Thanh, A.; Gompels, M.; Gonzalez-Quevedo, T.; Greve, J.; Guilarte, M.; Katelaris, C.; Dobo, S.; Cornpropst, M.; Clemons, D.; Fang, L.; Collis, P.; Sheridan, W.; Maurer, M.; Cicardi, M. | Journal Article |
2018 | Oxidation-Reduction Potential in Patients undergoing Transcatheter or Surgical Aortic Valve Replacement Heldmaier, K.; Stoppe, C.; Goetzenich, A.; Foldenauer, A.-C.; Zayat, R.; Breuer, T.; Schälte, G. | Journal Article |
2018 | The oxidized linoleic acid metabolite 12,13-DiHOME mediates thermal hyperalgesia during inflammatory pain Zimmer, B.; Angioni, C.; Osthues, T.; Toewe, A.; Thomas, D.; Pierre, S.C.; Geisslinger, G.; Scholich, K.; Sisignano, M. | Journal Article |
2018 | Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells Hitzel, J.; Lee, E.; Zhang, Y.; Bibli, S.I.; Li, X.; Zukunft, S.; Pflüger, B.; Hu, J.; Schürmann, C.; Vasconez, A.E.; Oo, J.A.; Kratzer, A.; Kumar, S.; Rezende, F.; Josipovic, I.; Thomas, D.; Giral, H.; Schreiber, Y.; Geisslinger, G.; Fork, C.; Yang, X.; Sigala, F.; Romanoski, C.E.; Kroll, J.; Jo, H.; Landmesser, U.; Lusis, A.J.; Namgaladze, D.; Fleming, I.; Leisegang, M.S.; Zhu, J.; Brandes, R.P. | Journal Article |
2018 | Pathophysiological mechanisms of neuropathic pain: comparison of sensory phenotypes in patients and human surrogate pain models Vollert, J,; Magerl, W.; Baron, R.; Binder, A.; Enax-Krumova, E.; Geisslinger, G.; Gierthmühlen, J.; Henrich, F.; Hüllemann, P.; Klein, T.; Lötsch, J.; Maier, C.; Oertel, B.; Schuh-Hofer, S.; Tölle, T.; Treede, R.-D. | Journal Article |
2018 | Physical behavior and sampling of airborne particles Hochrainer, D. | Book Article |
2018 | Plant-derived chimeric antibodies inhibit the invasion of human fibroblasts by Toxoplasma gondii Lim, S.S.Y.; Chua, K.H.; Nölke, G.; Spiegel, H.; Goh, W.L.; Chow, S.C.; Kee, B.P.; Fischer, R.; Schillberg, S.; Othman, R.Y. | Journal Article |
2018 | Plants as sources of natural and recombinant anti-cancer agents Buyel, J.F. | Journal Article |
2018 | Polarization of Human Macrophages by Interleukin-4 Does Not Require ATP-Citrate Lyase Namgaladze, D.; Zukunft, S.; Schnütgen, F.; Kurrle, N.; Fleming, I.; Fuhrmann, D.; Brüne, B. | Journal Article |
2018 | Polyamines delay leaf maturation in low‐alkaloid tobacco varieties Nölke, G.; Volke, D.; Chudobová, I.; Houdelet, M.; Lusso, M.; Frederick, J.; Adams, A.; Kudithipudi, C.; Warek, U.; Strickland, J.A.; Xu, D.; Schinkel, H.; Schillberg, S. | Journal Article |
2018 | Population-specific expression of antimicrobial peptides conferring pathogen resistance in the invasive ladybird Harmonia axyridis Gegner, T.; Schmidtberg, H.; Vogel, H.; Vilcinskas, A. | Journal Article |
2018 | The portal vein as a distinct immunological compartment Queck, A.; Rueschenbaum, S.; Kubesch, A.; Cai, C.; Zeuzem, S.; Weigert, A.; Brüne, B.; Nour-Eldin, A.; Gruber-Rouh, T.; Vogl, T.; Lange, C.M. | Journal Article |
2018 | Primary fish hepatocytes as in vitro test system to study the metabolism of xenobiotics in fish Bischof, Ina : Segner, Helmut; Schlechtriem, Christian | Dissertation |
2018 | Promoter construct for cell-free protein synthesis Buntru, Matthias; Schillberg, Stefan; Vogel, Simon | Patent |
2018 | The prostaglandin E2 receptor EP3 controls CC-chemokine ligand 2–mediated neuropathic pain induced by mechanical nerve damage Treutlein, E.-M.; Kern, K.; Weigert, A.; Tarighi, N.; Schuh, C.-D.; Nüsing, R.M.; Schreiber, Y.; Ferreirós, N.; Brüne, B.; Geisslinger, G.; Pierre, S.; Scholich, K. | Journal Article |
2018 | Proteomic analysis of CHO cell lines producing high and low quantities of a recombinant antibody before and after selection with methotrexate Hausmann, R.; Chudobová, I.; Spiegel, H.; Schillberg, S. | Journal Article |
2018 | Redox-signals and macrophage biology Weigert, A.; Knethen, A. von; Fuhrmann, D.; Dehne, N.; Brüne, B. | Journal Article |
2018 | A reference genome of the Chinese hamster based on a hybrid assembly strategy Rupp, O.; MacDonald, M.L.; Li, S.; Dhiman, H.; Polson, S.; Griep, S.; Heffner, K.; Hernandez, I.; Brinkrolf, K.; Jadhav, V.; Samoudi, M.; Hao, H.; Kingham, B.; Goesmann, A.; Betenbaugh, M.J.; Lewis, N.E.; Borth, N.; Lee, K.H. | Journal Article |
2018 | The relevance of ceramides and their synthesizing enzymes for multiple sclerosis Kurz, J.; Brunkhorst, R.; Foerch, C.; Blum, L.; Henke, M.; Gabriel, L.; Ulshöfer, T.; Ferreiros, N.; Parnham, M.J.; Geisslinger, G.; Schiffmann, S. | Journal Article |
2018 | Reliability of In Vitro Methods Used to Measure Intrinsic Clearance of Hydrophobic Organic Chemicals by Rainbow Trout Nichols, John; Fay, Kellie; Bernhard, Mary Jo; Bischof, Ina; Davis, John; Halder, Marlies; Hu, Jing; Johanning, Karla; Laue, Heike; Nabb, Diane; Schlechtriem, Christian; Segner, Helmut; Swintek, Joe; Weeks, John; Embry, Michelle | Journal Article |
2018 | Reliable high-density energy storage in Si-doped HfO2 thin films on 3D-structures Kühnel, Kati; Riedel, Stefan; Mart, Clemens; Weinreich, Wenke | Presentation |
2018 | Response of the Mayfly (Cloeon Dipterum) to chronic exposure to Thiamethoxam in outdoor Mesocosms Pickford, Daniel B.; Finnegan, Meaghean C.; Baxter, Leilan R.; Böhmer, Walter; Hanson, Mark L.; Stegger, Petra; Hommen, Udo; Hoekstra, Paul F.; Hamer, Mick | Journal Article |
2018 | Revisiting elimination half live as an indicator for bioaccumulation in fish and terrestrial mammals Goss, Kai-Uwe; Linden, Lukas; Ulrich, Nadin; Schlechtriem, Christian | Journal Article |
2018 | S2e-Leitlinie: Therapie der rheumatoiden Arthritis mit krankheitsmodifizierenden Medikamenten Fiehn, C.; Holle, J.; Iking-Konert, C.; Leipe, J.; Weseloh, C.; Frerix, M.; Alten, R.; Behrens, F.; Baerwald, C.; Braun, J.; Burkhardt, H.; Burmester, G.; Detert, J.; Gaubitz, M.; Gause, A.; Gromnica-Ihle, E.; Kellner, H.; Krause, A.; Kuipers, J.; Lorenz, H.-M.; Müller-Ladner, U.; Nothacker, M.; Nüsslein, H.; Rubbert-Roth, A.; Schneider, M.; Schulze-Koops, H.; Seitz, S.; Sitter, H.; Specker, C.; Tony, H.-P.; Wassenberg, S.; Wollenhaupt, J.; Krüger, K. | Journal Article |
2018 | Safety and efficacy of ixekizumab in patients with PsA and previous inadequate response to TNF inhibitors: week 52 results from SPIRIT-P2 Genovese, M.C.; Combe, B.; Kremer, J.M.; Tsai, T.-F.; Behrens, F.; Adams, D.H.; Lee, C.; Kerr, L.; Nash, P. | Journal Article |
2018 | Scientific Opinion about the Guidance of the Chemical Regulation Directorate (UK) on how aged sorption studies for pesticides should be conducted, analysed and used in regulatory assessments Ockleford, Colin; Hernandez-Jerez, Antonio F.; Hougaard Bennekou, Susanne; Klein, Michael; et. al. | Journal Article |
2018 | Scientific opinion on pesticides in foods for infants and young children Ockleford, Colin; Adriaanse, Paulien; Hougaard Bennekou, Susanne; Berny, Philippe; Brock, Theodorus; Duquesne, Sabine; Grilli, Sandro; Hernandez-Jerez, Antonio F.; Klein, Michael; Kuhl, Thomas; Laskowski, Ryszard; Machera, Kyriaki; Pelkonen, Olavi; Pieper, Silvia; Smith, Robert; Stemmer, Michael; Sundh, Ingvar; Teodorovic, Ivana; Tiktak, Aaldrik; Topping, Chris J.; Gundert-Remy, Ursula; Kersting, Mathilde; Waalkens-Berendsen, Ine; Chiusolo, Arianna; Court Marques, Daniele; Dujardin, Bruno; Kass, Georges E; Mohimont, Luc; Nougadere, Alexandre; Reich, Hermine; Wolterink, Gerrit | Journal Article |
2018 | Scientific Opinion on the state of the art of Toxicokinetic/Toxicodynamic (TKTD) effect models for regulatory risk assessment of pesticides for aquatic organisms Ockleford, Colin; Adriaanse, Paulien; Berny, Philippe; Brock, Theodorus; Duquesne, Sabine; Grilli, Sandro; Hernandez-Jerez, Antonio F.; Hougaard Bennekou, Susanne; Klein, Michael; et. al. | Journal Article |
2018 | Scientific Opinion on the state of the science on pesticide risk assessment for amphibians and reptiles Ockleford, Colin; Adriaanse, Paulien; Berny, Philippe; Brock, Theodorus; Duquesne, Sabine; Grilli, Sandro; Hernandez-Jerez, Antonio F.; Hougaard Bennekou, Susanne; Klein, Michael; Kuhl, Thomas; Laskowski, Ryszard; Machera, Kyriaki; Pelkonen, Olavi; Pieper, Silvia; Stemmer, Michael; Sundh, Ingvar; Teodorovic, Ivana; Tiktak, Aaldrik; Topping, Chris J.; Wolterink, Gerrit; Craig, Peter; Jong, Frank de; Manachini, Barbara; Sousa, Paulo; Swarowsky, Klaus; Auteri, Domenica; Arena, Maria; Smith, Rob | Journal Article |
2018 | Sicherheit und Wirksamkeitshinweise zum Off-label-Einsatz von Biologikatherapien nach Versagen konventioneller Therapien bei Patienten mit entzündlich rheumatischen Erkrankungen Proft, F.; Schulze-Koops, H.; Grunke, M.; Schrezenmeier, E.; Halleck, F.; Henes, J.; Unger, L.; Schmidt, E.; Fiehn, C.; Jacobi, A.; Iking-Konert, C.; Kneitz, C.; Schmidt, R.E.; Bannert, B.; Voll, R.E.; Fischer-Betz, R.; Kötter, I.; Tony, H.P.; Holle, J.; Aringer, M.; Erler, A.; Behrens, F.; Burmester, G.R.; Dörner, T. | Journal Article |
2018 | Silver nanoparticles in sewage sludge: Bioavailability of sulfidized silver to the terrestrial isopod Porcellio scaber Kampe, Sebastian; Kägi, Ralf; Schlich, Karsten; Wasmuth, Claus; Hollert, Henner; Schlechtriem, Christian | Journal Article |
2018 | Silver nanoparticles in sewage treatment plant effluents: Chronic effects and accumulation of silver in the freshwater amphipod Hyalella azteca Kühr, Sebastian; Schneider, Stefanie; Meisterjahn, Boris; Schlich, Karsten; Hund-Rinke, Kerstin; Schlechtriem, Christian | Journal Article |
2018 | Simultaneous and Independent Dual Site-Specific Self-Labeling of Recombinant Antibodies Wollschläger, C.; Meinhold-Heerlein, I.; Cong, X.; Bräutigam, K.; Fiore, S. Di; Zeppernick, F.; Klockenbring, T.; Stickeler, E.; Barth, S.; Hussain, A.F. | Journal Article |
2018 | Simultaneous determination of PUFA-derived pro-resolving metabolites and pathway markers using chiral chromatography and tandem mass spectrometry Toewe, A.; Balas, L.; Durand, T.; Geisslinger, G.; Ferreirós, N. | Journal Article |
2018 | Simultaneous response in several domains in patients with psoriatic disease treated with etanercept as monotherapy or in combination with conventional synthetic disease-modifying antirheumatic drugs Behrens, F.; Meier, L.; Prinz, J.C.; Jobst, J.; Lippe, R.; Löschmann, P.-A.; Lorenz, H.-M. | Journal Article |
2018 | Single-cell cloning enables the selection of more productive Drosophila melanogaster S2 cells for recombinant protein expression Zitzmann, J.; Schreiber, C.; Eichmann, J.; Bilz, R.O.; Salzig, D.; Weidner, T.; Czermak, P. | Journal Article |
2018 | The siRNA-mediated knockdown of GluN3A in 46C-derived neural stem cells affects mRNA expression levels of neural genes, including known iGluR interactors Pachernegg, Svenja; Eilebrecht, Sebastian; Eilebrecht, Elke; Schöneborn, Hendrik; Neumann, Sebastian; Benecke, Arndt G.; Hollmann, Michael | Journal Article |
2018 | Small rubber particle proteins from Taraxacum brevicorniculatum promote stress tolerance and influence the size and distribution of lipid droplets and artificial poly(cis-1,4-isoprene) bodies Laibach, N.; Schmidl, S.; Müller, B.; Bergmann, M.; Prüfer, D.; Schulze Gronover, C. | Journal Article |
2018 | The sneaking ligand approach for cell type-specific modulation of intracellular signalling pathways Sehnert, B.; Burkhardt, H.; Finzel, S.; Dübel, S.; Voll, R.E. | Journal Article |
2018 | Soil bacteria isolated from tunisian arid areas show promising antimicrobial activities against gram-negatives Nasfi, Z.; Busch, H.; Kehraus, S.; Linares-Otoya, L.; König, G.M.; Schäberle, T.F.; Bachoual, R. | Journal Article |
2018 | Sphingosine kinase 2 modulates retinal neovascularization in the mouse model of oxygen-induced retinopathy Eresch, J.; Stumpf, M.; Koch, A.; Vutukuri, R.; Ferreiros, N.; Schreiber, Y.; Schröder, K.; Devraj, K.; Popp, R.; Huwiler, A.; Hattenbach, L.-O.; Pfeilschifter, J.; Pfeilschifter, W. | Journal Article |
2018 | Sphingosine‐1‐phosphate (S1P) induces potent anti‐inflammatory effects in vitro and in vivo by S1P receptor 4‐mediated suppression of 5‐lipoxygenase activity Fettel, J.; Kühn, B.; Guillen, N.A.; Sürün, D.; Peters, M.; Bauer, R.; Angioni, C.; Geisslinger, G.; Schnütgen, F.; Meyer zu Heringdorf, D.; Werz, O.; Meybohm, P.; Zacharowski, K.; Steinhilber, D.; Roos, J.; Maier, T.J. | Journal Article |
2018 | Statistische Auswertung von Messungen zur Kontamination von Biota/Fischen mit Schadstoffen im Einzugsgebiet des Rheins in den Jahren 2014/2015 Fliedner, Annette; Müller, Martin | Report |
2018 | Stellenwert der Kombination von Biologika mit Methotrexat in der Behandlung der Psoriasisarthritis - Fragen bleiben offen Dauth, S.; Köhm, M.; Rossmanith, T.; Herrmann, E.; Lehn, A.; Burkhardt, H.; Behrens, F. | Journal Article |
2018 | The structural basis for cancer drug interactions with the catalytic and allosteric sites of SAMHD1 Knecht, K.M.; Buzovetsky, O.; Schneider, C.; Thomas, D.; Srikanth, V.; Kaderali, L.; Tofoleanu, F.; Reiss, K.; Ferreirós, N.; Geisslinger, G.; Batista, V.S.; Ji, X.; Cinatl, J.; Keppler, O.T.; Xiong, Y. | Journal Article |
2018 | Structure-activity analysis of CJ-15,801 analogues that interact with Plasmodium falciparum pantothenate kinase and inhibit parasite proliferation Spry, C.; Sewell, A.L.; Hering, Y.; Villa, M.V.J.; Weber, J.; Hobson, S.J.; Harnor, S.J.; Gul, S.; Marquez, R.; Salib, K.J. | Journal Article |
2018 | Synaptic phospholipids as a new target for cortical hyperexcitability and E/I balance in psychiatric disorders Thalman, C.; Horta, G.; Qiao, L.; Endle, H.; Tegeder, I.; Cheng, H.; Laube, G.; Sigurdsson, T.; Hauser, M.J.; Tenzer, S.; Distler, U.; Aoki, J.; Morris, A.J.; Geisslinger, G.; Röper, J.; Kirischuk, S.; Luhmann, H.J.; Radyushkin, K.; Nitsch, R.; Vogt, J. | Journal Article |
2018 | T Cell Phenotype and T Cell Receptor Repertoire in Patients with Major Depressive Disorder Patas, K.; Willing, A.; Demiralay, C.; Engler, J.B.; Lupu, A.; Ramien, C.; Schäfer, T.; Gach, C.; Stumm, L.; Chan, K.; Vignali, M.; Arck, P.C.; Friese, M.A.; Pless, O.; Wiedemann, K.; Agorastos, A.; Gold, S.M. | Journal Article |
2018 | Taraxacum brevicorniculatum rubber elongation factor TbREF associates with lipid droplets and affects lipid turn-over in yeast Bröker, J.N.; Laibach, N.; Müller, B.; Prüfer, D.; Schulze Gronover, C. | Journal Article |
2018 | Therapeutics discovery: From bench to first in-human trials Al-Hujaily, E.M.; Khatlani, T.; Alehaideb, Z.; Ali, R.; Almuzaini, B.; Alrfaei, B.M.; Iqbal, J.; Islam, I.; Malik, S.; Marwani, B.A.; Massadeh, S.; Muzaini, B.; Nehdi, A.; Alsomaie, B.; Debasi, B.; Bushnak, I.; Noibi, S.; Hussain, S.; Wajid, W.A.; Armand, J.-P.; Gul, S.; Oyarzabal, J.; Rais, R.; Bountra, C.; Alaskar, A.; Al Knawy, B.; Boudjelal, M. | Journal Article |
2018 | Three-Dimensional Bioreactor Technologies for the Cocultivation of Human Mesenchymal Stem/Stromal Cells and Beta Cells Petry, F.; Weidner, T.; Czermak, P.; Salzig, D. | Journal Article |
2018 | Total Synthesis and Structural Revision of the Antibiotic Tetrapeptide GE81112A Jürjens, G.; Schuler, S.M.M.; Kurz, M.; Petit, S.; Couturier, C.; Jeannot, F.; Nguyen, F.; Wende, R.C.; Hammann, P.E.; Wilson, D.N.; Bacqué, E.; Pöverlein, C.; Bauer, A. | Journal Article |
2018 | Two-pronged approach to anti-inflammatory therapy through the modulation of the arachidonic acid cascade Sala, A.; Proschak, E.; Steinhilber, D.; Rovati, G.E. | Journal Article |
2018 | UDP-glucose ceramide glucosyltransferase activates AKT, promoted proliferation, and doxorubicin resistance in breast cancer cells Wegner, M.-S.; Schömel, N.; Gruber, L.; Örtel, S.B.; Kjellberg, M.A.; Mattjus, P.; Kurz, J.; Trautmann, S.; Peng, B.; Wegner, M.; Kaulich, M.; Ahrends, R.; Geisslinger, G.; Grösch, S. | Journal Article |
2018 | The UDP-glucose ceramide glycosyltransferase (UGCG) and the link to multidrug resistance protein 1 (MDR1) Wegner, M.-S.; Gruber, L.; Mattjus, P.; Geisslinger, G.; Grösch, S. | Journal Article |
2018 | A unique fungal strain collection from Vietnam characterized for high performance degraders of bioecological important biopolymers and lipids Brandt, S.C.; Ellinger, B.; Nguyen, T. van; Thi, Q.D.; Nguyen, G. van; Baschien, C.; Yurkov, A.; Hahnke, R.L.; Schäfer, W.; Gand, M. | Journal Article |
2018 | Untersuchungen zur Regulation der Leukotrien-Biosynthese durch Sphingosin-1-Phosphat Fettel, J. | Dissertation |
2018 | Upregulating the mevalonate pathway and repressing sterol synthesis in Saccharomyces cerevisiae enhances the production of triterpenes Bröker, J.N.; Müller, B.; Deenen, N. van; Prüfer, D.; Schulze Gronover, C. | Journal Article |
2018 | Uptake and effects of cerium(III) and cerium oxide nanoparticles to Chlamydomonas reinhardtii Kosak, Lena A.; Brandt, Tanja; Sigg, Laura; Behra, Renata | Journal Article |
2018 | Urate transporter inhibitor lesinurad is a selective peroxisome proliferator-activated receptor gamma modulator (sPPARγM) in vitro Heitel, P.; Gellrich, L.; Heering, J.; Goebel, T.; Kahnt, A.; Proschak, E.; Schubert-Zsilavecz, M.; Merk, D. | Journal Article |
2018 | Urate transporter inhibitor lesinurad is a selective peroxisome proliferator-activated receptor gamma modulator (sPPARγM) in vitro Heitel, P.; Gellrich, L.; Heering, J.; Goebel, T.; Kahnt, A.; Proschak, E.; Schubert-Zsilavecz, M.; Merk, D. | Journal Article |
2018 | Use of Computational Functional Genomics in Drug Discovery and Repurposing for Analgesic Indications Lötsch, J.; Kringel, D. | Journal Article |
2018 | When facing multiple enemies: the impact of host development time and exposure to multiple parasites in shaping coevolutionary adaptations in host and parasites Biswas, T. | Dissertation |
2017 | Activated platelets induce an anti-inflammatory response of monocytes/macrophages through cross-regulation of PGE2 and cytokines Linke, B.; Schreiber, Y.; Picard-Willems, B.; Slattery, P.; Nüsing, R.M.; Harder, S.; Geisslinger, G.; Scholich, K. | Journal Article |
2017 | AMP-activated kinase and the endogenous endocannabinoid system might contribute to antinociceptive effects of prolonged moderate caloric restriction in mice King-Himmelreich, T.S.; Möser, C.V.; Wolters, M.C.; Schmetzer, J.; Möller, M.; Schreiber, Y. | Journal Article |
2017 | AMPK contributes to aerobic exercise-induced antinociception downstream of endocannabinoids King-Himmelreich, T.S.; Möser, C.V.; Wolters, M.C.; Schmetzer, J.; Schreiber, Y.; Ferreirós, N.; Russe, O.Q.; Geisslinger, G.; Niederberger, E. | Journal Article |
2017 | Anaerobic Membrane Bioreactor for Continuous Lactic Acid Fermentation Fan, R.; Ebrahimi, M.; Czermak, P. | Journal Article |
2017 | Analysis of virus susceptibility in the invasive insect pest Drosophila suzukii Kwang-Zin, L.; Vilcinskas, A. | Journal Article |
2017 | Animal component-free Agrobacterium tumefaciens cultivation media for better GMP-compliance increases biomass yield and pharmaceutical protein expression in Nicotiana benthamiana Houdelet, M.; Galinski, A.; Holland, T.; Wenzel, K.; Schillberg, S.; Buyel, J.F. | Journal Article |
2017 | Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage Ge, C.; Tong, D.; Liang, B.; Lönnblom, E.; Schneider, N.; Hagert, C.; Viljanen, J.; Ayoglu, B.; Stawikowska, R.; Nilsson, P.; Fields, G.B.; Skogh, T.; Kastbom, A.; Kihlberg, J.; Burkhardt, H.; Dobritzsch, D.; Holmdahl, R. | Journal Article |
2017 | Anti-GPVI Fab SAR264565 effectively blocks GPVI function in ex vivo human platelets under arterial shear in a perfusion chamber Florian, P.; Wonerow, P.; Harder, S.; Kuczka, K.; Dubar, M.; Graff, J. | Journal Article |
2017 | Antibodies from plants for bionanomaterials Edgue, G.; Twyman, R.M.; Beiss, V.; Fischer, R.; Sack, M. | Journal Article |
2017 | Apoptotic Diminution of Immature Single and Double Positive Thymocyte Subpopulations Contributes to Thymus Involution During Murine Polymicrobial Sepsis Netzer, C.; Knape, T.; Kuchler, L.; Weigert, A.; Zacharowski, K.; Pfeilschifter, W.; Sempowski, G.; Parnham, M.J.; Brüne, B.; Knethen, A. von | Journal Article |
2017 | Baculovirus-induced recombinant protein expression in human mesenchymal stromal stem cells: A promoter study Sprick, G.; Weidner, T.; Salzig, D.; Czermak, P. | Journal Article |
2017 | BCX7353, a once-daily oral kallikrein inhibitor, is effective and safe in the prophylaxis of acute attacks in patients with hereditary angioedema: Attack-level analysis of the APeX-1 study Aygören, E.; Bygum, A.; Steiner, U.; Magerl, M.; Panovska, V.G.; Farkas, H.; Huissoon, A.; Graff, J.; Lleonart, R.; Rae, W.; Aberer, W.; Longhurst, H.; Smith, W.; Zanichelli, A.; Cancian, M.; Guilarte, M.; Triggiani, M.; Gompels, M.; Fang, L.; Cornpropst, M.; Clemons, D.; Collis, P.; Dobo, S.; Sheridan, W.P.; Maurer, M.; Cicardi, M. | Abstract |
2017 | Behavioral and immunological features promoting the invasive performance of the harlequin ladybird Harmonia axyridis Verheggen, F.J.; Vogel, H.; Vilcinskas, A. | Journal Article |
2017 | Bewertung der Grundwasserbelastung durch Wirkstoffe - was wollen wir schützen? Schäfers, Christoph | Conference Paper |
2017 | Bewertung des Eintrags von Pflanzenschutzmitteln in Oberflächengewässer - Runoff, Erosion und Drainage Bach, Martin; Guerniche, Djamal; Thomas, Kai; Trapp, Matthias; Kubiak, Roland; Hommen, Udo; Klein, Michael; Reichenberger, Stefan; Pires, José; Preuß, Thomas | Report |
2017 | Beyond Immune Cell Migration Olesch, C.; Ringel, C.; Brüne, B.; Weigert, A. | Journal Article |
2017 | Bioactivity of natural and engineered antimicrobial peptides from venom of the scorpions urodacus yaschenkoi and U. Manicatus Luna-Ramirez, K.; Tonk, M.; Rahnamaeian, M.; Vilcinskas, A. | Journal Article |
2017 | Bioluminescence and Near-infrared Imaging of Optic Neuritis and Brain Inflammation in the EAE Model of Multiple Sclerosis in Mice Schmitz, K.; Tegeder, I. | Journal Article |
2017 | Biophysical characterization of E. coli TolC interaction with the known blocker hexaamminecobalt Gilardi, A.; Bhamidimarri, S.P.; Brönstrup, M.; Bilitewski, U.; Marreddy, R.K.R.; Pos, K.M.; Benier, L.; Gribbon, P.; Winterhalter, M.; Windshügel, B. | Journal Article |
2017 | Blanchieren vereinfacht die Reinigung rekombinanter Proteine aus Pflanzen Buyel, J.F. | Journal Article |
2017 | Building early-larval sexing systems for genetic control of the Australian sheep blow fly Lucilia cuprina using two constitutive promoters Yan, Y.; Linger, R.J.; Scott, M.J. | Journal Article |
2017 | Burying beetles regulate the microbiome of carcasses and use it to transmit a core microbiota to their offspring Shukla, S.P.; Vogel, H.; Heckel, D.G.; Vilcinskas, A.; Kaltenpoth, M. | Journal Article |
2017 | Camptothecin and its analog SN-38, the active metabolite of irinotecan, inhibit binding of the transcriptional regulator and oncoprotein FUBP1 to its DNA target sequence FUSE Hosseini, S.K.; Kolterer, S.; Steiner, M.; Manstein, V. von; Gerlach, K.; Trojan, J.; Waidmann, O.; Zeuzem, S.; Schulze, J.O.; Hahn, S.; Steinhilber, D.; Gatterdam, V.; Tampé, R.; Biondi, R.M.; Proschak, E.; Zörnig, M. | Journal Article |
2017 | Can solid-phase microextraction replace solvent extraction for water analysis in fish bioconcentration studies with highly hydrophobic organic chemicals? Böhm, L.; Düring, R.-A.; Bruckert, H.-J.; Schlechtriem, C. | Journal Article |
2017 | Cancer cell and macrophage cross-talk in the tumor microenvironment Dehne, N.; Mora, J.; Namgaladze, D.; Weigert, A.; Brüne, B. | Journal Article |
2017 | Cannabinoid antagonist SLV326 induces convulsive seizures and changes in the interictal EEG in rats Perescis, M.F.J.; Bruin, N. de; Heijink, L.; Kruse, C.; Vinogradova, L.; Lüttjohann, A.; Luijtelaar, G. van; Rijn, C.M. van | Journal Article |
2017 | CarbORev‐5901: The First Carborane‐Based Inhibitor of the 5‐Lipoxygenase Pathway Kuhnert, R.; Sárosi, M.-B.; George, S.; Lönnecke, P.; Hofmann, B.; Steinhilber, D.; Murganic, B.; Mijatovic, S.; Maksimovic‐Ivanic, D.; Hey‐Hawkins, E. | Journal Article |
2017 | CD200 selectively upregulates prostaglandin E2 and D2 synthesis in LPS-treated bone marrow-derived macrophages Kern, K.; Pierre, S.; Schreiber, Y.; Angioni, C.; Thomas, D.; Ferreirós, N.; Geisslinger, G.; Scholich, K. | Journal Article |
2017 | Ceramide synthase 2 deficiency aggravates AOM-DSS-induced colitis in mice Oertel, S.; Scholich, K.; Weigert, A.; Thomas, D.; Schmetzer, J.; Trautmann, S.; Wegner, M.S.; Radeke, H.H.; Filmann, N.; Brüne, B.; Geisslinger, G.; Tegeder, I.; Grösch, S. | Journal Article |
2017 | Cetuximab Resistance in Head and Neck Cancer Is Mediated by EGFR-K-521 Polymorphism Braig, F.; Kriegs, M.; Voigtlaender, M.; Habel, B.; Grob, T.; Biskup, K.; Blanchard, V.; Sack, M.; Thalhammer, A.; Ben Batalla, I.; Braren, I.; Laban, S.; Danielczyk, A.; Goletz, S.; Jakubowicz, E.; Märkl, B.; Trepel, M.; Knecht, R.; Riecken, K.; Fehse, B.; Loges, S.; Bokemeyer, C.; Binder, M. | Journal Article |
2017 | Challenges in assigning endocrine-specific modes of action: Recommendations for researchers and regulators Mihaich, Ellen M.; Schäfers, Christoph; Dreier, David A.; Hecker, Markus; Ortego, Lisa; Kawashima, Yukio; Dang, Zhi-Chao; Solomon, Keith | Journal Article |
2017 | Challenges in the drug release testing of next-generation nanomedicines - what do we know? Wacker, M.G. | Journal Article, Conference Paper |
2017 | Characteristics of Genome Editing Mutations in Cereal Crops Zhu, C.; Bortesi, L.; Baysal, C.; Twyman, R.M.; Fischer, R.; Capell, T.; Schillberg, S.; Christou, P. | Journal Article |
2017 | Characterization and cellular localization of human 5-lipoxygenase and its protein isoforms 5-LOΔ13, 5-LOΔ4 and 5-LOp12 Ball, A.-K.; Beilstein, K.; Wittmann, S.; Sürün, D.; Saul, M.J.; Schnütgen, F.; Flamand, N.; Capelo, R.; Kahnt, A.S.; Frey, H.; Schaefer, L.; Marschalek, R.; Häfner, A.-K.; Steinhilber, D. | Journal Article |
2017 | Characterization of novel insect cytochrome P450-fusion enzymes Talmann, L. | Dissertation |
2017 | Characterization of the molecular mechanism of 5-lipoxygenase inhibition by 2-aminothiazoles Kretschmer, S.B.M.; Woltersdorf, S.; Vogt, D.; Lillich, F.F.; Rühl, M.; Karas, M.; Maucher, I.V.; Roos, J.; Häfner, A.-K.; Kaiser, A.; Wurglics, M.; Schubert-Zsilavecz, M.; Angioni, C.; Geisslinger, G.; Stark, H.; Steinhilber, D.; Hofmann, B. | Journal Article |
2017 | Charakterisierung der thymalen T-Zell-Reifung und -Auswanderung während der Sepsis mittels TRECs Netzer, C. | Dissertation |
2017 | Charakterisierung und Evaluierung neuartiger Antikörperfragment-Immunkonjugate basierend auf der SNAP-Tag Technologie Woitok, M. | Dissertation |
2017 | Chroman-4-One Derivatives Targeting Pteridine Reductase 1 and Showing Anti-Parasitic Activity Pisa, F. di; Landi, G.; Iacono, L. dello; Pozzi, C.; Borsari, C.; Ferrari, S.; Santucci, M.; Santarem, N.; Cordeiro-da-Silva, A.; Moraes, C.B.; Alcantara, L.M.; Fontana, V.; Freitas, L.H.; Gul, S.; Kuzikov, M.; Behrens, B.; Pöhner, I.; Wade, R.C.; Costi, M.P.; Mangani, S. | Journal Article |
2017 | Classification of baseline toxicants for QSAR predictions to replace fish acute toxicity studies Nendza, Monika; Müller, Martin; Wenzel, Andrea | Journal Article |
2017 | Cleavage of SNAP‐25 ameliorates cancer pain in a mouse model of melanoma Olbrich, K.; Costard, L.; Möser, C.V.; Syhr, K.M.J.; King‐Himmelreich, T.S.; Wolters, M.C.; Schmidtko, A.; Geisslinger, G.; Niederberger, E. | Journal Article |
2017 | Combination of two epitope identification techniques enables the rational design of soy allergen Gly m 4 mutants Havenith, Heide; Kern, Karolin; Rautenberger, Paul; Spiegel, Holger; Szardenings, Michael; Ueberham, Elke; Lehmann, Jörg; Buntru, Matthias; Vogel, Simon; Treudler, Regina; Fischer, Rainer; Schillberg, Stefan | Journal Article |
2017 | Combined 15N-Labeling and TandemMOAC Quantifies Phosphorylation of MAP Kinase Substrates Downstream of MKK7 in Arabidopsis Huck, N.V.; Leissing, F.; Majovsky, P.; Buntru, M.; Aretz, C.; Flecken, M.; Müller, J.P.J.; Vogel, S.; Schillberg, S.; Hoehenwarter, W.; Conrath, U.; Beckers, G.J.M. | Journal Article |
2017 | Comparative Analysis of Achievement of Individual Important Response Measured By DAS28dcrit in a Randomized Head-to-Head Trial of Tocilizumab Vs. Adalimumab in Active Rheumatoid Arthritis Koehm, M.; Hofmann, M.; Lüthje, R.; McIntosh, M.; Abraham, V.; Gabay, C.; Kavanaugh, A.; Burkhardt, H.; Behrens, F. | Abstract |
2017 | Comparison of a mouse and a novel human scFv-SNAP-auristatin F drug conjugate with potent activity against EGFR-overexpressing human solid tumor cells Woitok, M.; Klose, D.; Fiore, S. di; Richter, W.; Stein, C.; Gresch, G.; Grieger, E.; Barth, S.; Fischer, R.; Kolberg, K.; Niesen, J. | Journal Article |
2017 | Comparison of in-vitro and ex-vivo wound healing assays for the investigation of diabetic wound healing and demonstration of a beneficial effect of a triterpene extract Ueck, C.; Volksdorf, T.; Houdek, P.; Vidal-Y-Sy, S.; Sehner, S.; Ellinger, B.; Lobmann, R.; Larena-Avellaneda, A.; Reinshagen, K.; Ridderbusch, I.; Kohrmeyer, K.; Moll, I.; Daniels, R.; Werner, P.; Merfort, I.; Brandner, J.M. | Journal Article |
2017 | The components of shear stress affecting insect cells used with the baculovirus expression vector system Weidner, T.; Druzinec, D.; Mühlmann, M.; Buchholz, R.; Czermak, P. | Journal Article |
2017 | Concentration dependent transcriptome responses of zebrafish embryos after exposure to cadmium, cobalt and copper Sonnack, Laura; Klawonn, Thorsten; Kriehuber, Ralf; Hollert, Henner; Schäfers, Christoph; Fenske, Martina | Journal Article |
2017 | Contained molecular farming using plant cell and tissue cultures Schillberg, S.; Raven, Nicole; Fischer, R.; Twyman, R.M.; Schiermeyer, A. | Book Article |
2017 | Crassiflorone derivatives that inhibit Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (TbGAPDH) and Trypanosoma cruzi trypanothione reductase (TcTR) and display trypanocidal activity Uliassi, E.; Fiorani, G.; Krauth-Siegel, R.L.; Bergamini, C.; Fato, R.; Bianchini, G.; Carlos Menéndez, J.; Molina, M.T.; López-Montero, E.; Falchi, F.; Cavalli, A.; Gul, S.; Kuzikov, M.; Ellinger, B.; Witt, G.; Moraes, C.B.; Freitas-Junior, L.H.; Borsari, C.; Costi, M.P.; Bolognesi, M.L. | Journal Article |
2017 | Cre/lox-Recombinase-Mediated Cassette Exchange for Reversible Site-Specific Genomic Targeting of the Disease Vector, Aedes aegypti Häcker, I.; Harrell II, R.A.; Eichner, G.; Pilitt, K.L.; O'Brochta, D.A.; Handler, A.M.; Schetelig, M.F. | Journal Article |
2017 | CRISPR-Cas9 System as a Genome Editing Tool in Sugarcane Augustine, S.M. | Book Article |
2017 | CRISPR/Cas-mediated gene editing using purified protein in Drosophila suzukii Kalajdzic, P.; Schetelig, M.F. | Journal Article |
2017 | A data science based standardized Gini index as a Lorenz dominance preserving measure of the inequality of distributions Ultsch, A.; Lötsch, J. | Journal Article |
2017 | Data visualizations to detect systematic errors in laboratory assay results Lötsch, J. | Journal Article |
2017 | A data-driven approach to responder subgroup identification after paired continuous theta burst stimulation Heidegger, T.; Hansen-Goos, O.; Batlaeva, O.; Annak, O.; Ziemann, U.; Lötsch, J. | Journal Article |
2017 | Design, Synthesis and Cellular Characterization of a Dual Inhibitor of 5-Lipoxygenase and Soluble Epoxide Hydrolase Meirer, K.; Glatzel, D.; Kretschmer, S.; Wittmann, S.K.; Hartmann, M.; Blöcher, R.; Angioni, C.; Geisslinger, G.; Steinhilber, D.; Hofmann, B.; Fürst, R.; Proschak, E. | Journal Article |
2017 | Detection and Specific Elimination of EGFR+ Ovarian Cancer Cells Using a Near Infrared Photoimmunotheranostic Approach Bauerschlag, D.; Meinhold-Heerlein, I.; Maass, N.; Bleilevens, A.; Bräutigam, K.; Al Rawashdeh, W.; Di Fiore, S.; Haugg, A.M.; Gremse, F.; Steitz, J.; Fischer, R.; Stickeler, E.; Barth, S.; Hussain, A.F. | Journal Article |
2017 | Detection of Clinical Signs of Arthritis and Subclinical Evidence of Inflammation in Psoriasis Patients with Risk for Arthritis: Value of Clinical Examination, Ultrasound and Fluorescence-Optical Imaging - Results from the Prospective Multicentre Xciting Study Koehm, M.; Rossmanith, T.; Langer, H.E.; Backhaus, M.; Burmester, G.R.; Wassenberg, S.; Köhler, B.; Burkhardt, H.; Behrens, F. | Abstract |
2017 | Detection of on-target and off-target mutations generated by CRISPR/Cas9 and other sequence-specific nucleases Zischewski, J.; Fischer, R.; Bortesi, L. | Journal Article |
2017 | Detection of tetrabromobisphenol A and its mono- and dimethyl derivatives in fish, sediment and suspended particulate matter from European freshwaters and estuaries Kotthoff, Matthias; Rüdel, Heinz; Jürling, Heinrich | Journal Article |
2017 | Development of cornerstones for a monitoring programme for the assessment of biocide emissions into the environment Rüdel, Heinz; Fliedner, Annette; Schwarzbauer, Jan; Wluka, Ann-Kathrin | Report |
2017 | Development of rubber-enriched dandelion varieties by metabolic engineering of the inulin pathway Stolze, A.; Wanke, A.; Deenen, N. van; Geyer, R.; Prüfer, D.; Schulze Gronover, C. | Journal Article |
2017 | The digestive and defensive basis of carcass utilization by the burying beetle and its microbiota Vogel, H.; Shukla, S.P.; Engl, T.; Weiss, B.; Fischer, R.; Steiger, S.; Heckel, D.G.; Kaltenpoth, M.; Vilcinskas, A. | Journal Article |
2017 | The dispersion releaser technology is an effective method for testing drug release from nanosized drug carriers Janas, C.; Mast, M.P.; Kirsamer, L.; Angioni, C.; Gao, F.; Mäntele, W.; Dressman, J.; Wacker, M.G. | Journal Article |
2017 | Diversity and phylogenetic analyses of bacterial symbionts in three whitefly species from Southeast Europe Skaljac, M.; Kanakala, S.; Zanic, K.; Puizina, J.; Pleic, I.L.; Ghanim, M. | Journal Article |
2017 | DrugBank screening revealed alitretinoin and bexarotene as liver X receptor modulators Heitel, P.; Achenbach, J.; Moser, D.; Proschak, E.; Merk, D. | Journal Article |
2017 | Drugging the pain epigenome Niederberger, E.; Resch, E.; Parnham, M.J.; Geisslinger, G. | Journal Article |
2017 | A dual modulator of farnesoid X receptor and soluble epoxide hydrolase to counter nonalcoholic steatohepatitis Schmidt, J.; Rotter, M.; Weiser, T.; Wittmann, S.; Weizel, L.; Kaiser, A.; Heering, J.; Goebel, T.; Angioni, C.; Wurglics, M.; Paulke, A.; Geisslinger, G.; Kahnt, A.; Steinhilber, D.; Proschak, E.; Merk, D. | Journal Article |
2017 | Durability of epoxy-bonded TiO2-modified aggregate as a photocatalytic coating layer for asphalt pavement under vehicle tire polishing Wang, D.; Leng, Z.; Yu, H.; Hüben, M.; Kollmann, J.; Oeser, M. | Journal Article |
2017 | Dysregulation of lysophosphatidic acids in multiple sclerosis and autoimmune encephalomyelitis Schmitz, K.; Brunkhorst, R.; Bruin, N. de; Mayer, C.A.; Häussler, A.; Ferreiros, N.; Schiffmann, S.; Parnham, M.J.; Tunaru, S.; Chun, J.; Offermanns, S.; Foerch, C.; Scholich, K.; Vogt, J.; Wicker, S.; Lötsch, J.; Geisslinger, G.; Tegeder, I. | Journal Article |
2017 | Ecotoxicity and fate of a silver nanomaterial in an outdoor lysimeter study Schlich, Karsten; Hoppe, Martin; Kraas, Marco; Fries, Elke; Hund-Rinke, K. | Journal Article |
2017 | Editorial: Special issue of the 6th European Workshop on Lipid Mediators Steinhilber, D.; Uydeş-Doğan, B.S.; Topal, G.; Clària, J.; Norel, X.; Schebb, N.H.; Bannenberg, G. | Journal Article |
2017 | Effects of oral Δ9-tetrahydrocannabinol on the cerebral processing of olfactory input in healthy non-addicted subjects Walter, C.; Oertel, B.G.; Felden, L.; Nöth, U.; Vermehren, J.; Deichmann, R.; Lötsch, J. | Journal Article |
2017 | Efficient Reduction of Antibacterial Activity and Cytotoxicity of Fluoroquinolones by Fungal-Mediated N-Oxidation Rusch, M.; Spielmeyer, A.; Meissner, J.; Kietzmann, M.; Zorn, H.; Hamscher, G. | Journal Article |
2017 | Efficient targeting of CD13 on cancer cells by the immunotoxin scFv13-ETA ' and the bispecific scFv [13xds16] Grieger, E.; Gresch, G.; Niesen, J.; Woitok, M.; Barth, S.; Fischer, R.; Fendel, R.; Stein, C. | Journal Article |
2017 | EFSA Guidance Document for predicting environmental concentrations of active substances of plant protection products and transformation products of these active substances in soil Tiktak, Aaldrik; Stemmer, Michael; Boesten, Jos; Klein, Michael; et. al. | Journal Article |
2017 | Einfluss der Klärschlammvorbehandlung durch Sulfidierung auf die Bioverfügbarkeit von Silbernanomaterialien bei der anschließenden Klärschlammverwertung auf landwirtschaftlichen Flächen Kraas, M. | Dissertation |
2017 | Elevated intrathymic sphingosine-1-phosphate promotes thymus involution during sepsis Kuchler, L.; Sha, L.K.; Giegerich, A.K.; Knape, T.; Angioni, C.; Ferreiros, N.; Schmidt, M.V.; Weigert, A.; Brüne, B.; Knethen, A. von | Journal Article |
2017 | Emergent biomarker derived from next-generation sequencing to identify pain patients requiring uncommonly high opioid doses Kringel, D.; Ultsch, A.; Zimmermann, M.; Jansen, J.P.; Ilias, W.; Freynhagen, R.; Griessinger, N.; Kopf, A.; Stein, C.; Doehring, A.; Resch, E.; Lötsch, J. | Journal Article |
2017 | Encapsulation of nor-beta-lapachone into poly(d,l)-lactide-: Co -glycolide (PLGA) microcapsules: Full characterization, computational details and cytotoxic activity against human cancer cell lines Costa, M.P.; Feitosa, A.C.S.; Oliveira, F.C.E.; Cavalcanti, B.C.; Dias, G.G.; Caetano, E.W.S.; Sales, F.A.M.; Freire, V.N.; Fiore, S. di; Fischer, R.; Ladeira, L.O.; Silva Junior, E.N. da; Pessoa, C. | Journal Article |
2017 | Endogenous egg immune defenses in the yellow mealworm beetle (Tenebrio molitor) Jacobs, C.G.C.; Gallagher, J.D.; Evision, S.E.F.; Heckel, D.G.; Vilcinskas, A.; Vogel, H. | Journal Article |
2017 | Enforced polarization of melanoma cells towards a JARID1B-high phenotype exhausts tumour fitness Chauvistre, H.; Shannan, B.; Vogel, F.; Krepler, C.; Picard, D.; Remke, M.; Haass, N.; Daignault, S.; Keminer, O.; Gul, S.; Sechi, A.; Lorberg, N.; Zarschler, D.; Höwner, A.; Becher, C.; Liu, Q.; Herlyn, M.; Schadendorf, D.; Roesch, A. | Abstract |
2017 | Engineering von intrazellulären Modulatoren Wiechmann, S.; Ernst, A. | Journal Article |
2017 | The entomopathogenic fungus Metarhizium robertsii communicates with the insect host Galleria mellonella during infection Mukherjee, K.; Vilcinskas, A. | Journal Article |
2017 | Entwicklung eines Expressionsscreenings zur Herstellung antimikrobieller Peptide Schreiber, C. | Dissertation |
2017 | Environmental risk assessment strategy for nanomaterials Scott-Fordsmand, Janeck J.; Peijnenburg, Willie J.G.M.; Semenzin, Elena; Nowack, Bernd; Hunt, Neil; Hristozov, Danail; Marcomini, Antonio; Irfan, Muhammad-Adeel; Jiménez, Araceli Sánchez; Landsiedel, Robert; Tran, Lang; Oomen, Agnes G.; Bos, Peter M.J.; Hund-Rinke, Kerstin | Journal Article |
2017 | Environmentally sustainable pest control options for Drosophila suzukii Schetelig, M.F.; Lee, K.‐Z.; Otto, S.; Talmann, L.; Stökl, J.; Degenkolb, T.; Vilcinskas, A.; Halitschke, R. | Journal Article |
2017 | EpCAM and CSPG4 scFv based fusion proteins for the treatment of triple negative breast cancer Amoury, M. | Dissertation |
2017 | Epigenetic assays for chemical biology and drug discovery Gul, S. | Journal Article |
2017 | Epigenetic mechanisms regulate innate immunity against uropathogenic and commensal-like Escherichia coli in the surrogate insect model Galleria mellonella Heitmueller, M.; Billion, A.; Dobrindt, U.; Vilcinskas, A.; Mukherjee, K. | Journal Article |
2017 | Establishing the Secondary Metabolite Profile of the Marine Fungus: Tolypocladium geodes sp MF458 and Subsequent Optimisation of Bioactive Secondary Metabolite Production Kebede, B.; Wrigley, S.K.; Prashar, A.; Rahlff, J.; Wolf, M.; Reinshagen, J.; Gribbon, P.; Imhoff, J.F.; Silber, J.; Labes, A.; Ellinger, B. | Journal Article |
2017 | Evaluating the combination of a parasitoid and a predator for biological control of seed beetles (Chrysomelidae: Bruchinae) in stored beans Berger, A.; Degenkolb, T.; Vilcinskas, A.; Schöller, M. | Journal Article |
2017 | Evaluation of high-throughput isomiR identification tools: Illuminating the early isomiRome of Tribolium castaneum Amsel, D.; Vilcinskas, A.; Billion, A. | Journal Article |
2017 | Evaluation of MYBPC3 trans-splicing and gene replacement as therapeutic options in human iPSC-derived cardiomyocytes Prondzynski, M.; Krämer, E.; Laufer, S.D.; Shibamiya, A.; Pless, O.; Flenner, F.; Müller, O.J.; Münch, J.; Redwood, C.; Hansen, A.; Patten, M.; Eschenhagen, T.; Mearini, G.; Carrier, L. | Journal Article |
2017 | Experimental evolution of resistance against Bacillus thuringiensis in the insect model host Galleria mellonella results in epigenetic modifications Mukherjee, K.; Grizanova, E.; Chertkova, E.; Lehmann, R.; Dubovskiy, I.; Vilcinskas, A. | Journal Article |
2017 | Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery Linciano, P.; Dawson, A.; Pöhner, I.; Costa, D.M.; Sá, M.S.; Cordeiro-da-Silva, A.; Luciani, R.; Gul, S.; Witt, G.; Ellinger, B.; Kuzikov, M.; Gribbon, P.; Reinshagen, J.; Wolf, M.; Behrens, B.; Hannaert, V.; Michels, P.A.M.; Nerini, E.; Pozzi, C.; Pisa, F. di; Landi, G.; Santarem, N.; Ferrari, S.; Saxena, P.; Lazzari, S.; Cannazza, G.; Freitas-Junior, L.H.; Moraes, C.B.; Pascoalino, B.S.; Alcântara, L.M.; Bertolacini, C.P.; Fontana, V.; Wittig, U.; Müller, W.; Wade, R.C.; Hunter, W.N.; Mangani, S.; Costantino, L.; Costi, M.P. | Journal Article |
2017 | Expression and characterization of single elements from Chlamydomonas reinhardtii CO2 concentration mechanism in the chloroplast of C3 plants Barsoum, M. | Dissertation |
2017 | Expression und Charakterisierung von Sojaallergen-Varianten für Lebensmittelanalytik, Allergiediagnostik und Therapeutik Havenith, H. | Dissertation |
2017 | Fine Tuning Antibody Conjugation Methods using SNAP-tag Technology Chouman, K.; Woitok, M.; Mladenov, R.; Kessler, C.; Weinhold, E.; Hanz, G.; Fischer, R.; Meinhold-Heerlein, I.; Bleilevens, A.; Gresch, G.; Haugg, A.M.; Zeppernick, F.; Bauerschlag, D.; Maass, N.; Stickeler, E.; Kolberg, K.; Hussain, A.F. | Journal Article |
2017 | Fish bioconcentration studies with column-generated analyte concentrations of highly hydrophobic organic chemicals Schlechtriem, Christian; Böhm, Leonard; Bebon, Rebecca; Bruckert, Hans-Jörg; Düring, Rolf-Alexander | Journal Article |
2017 | Flow Cytometer Monitoring of Bnip3- and Bnip3L/Nix-Dependent Mitophagy Šprung, M.; Dikic, I.; Novak, I. | Book Article |
2017 | Fraunhofer-Institut für Molekularbiologie und Angewandte Oekologie. Jahresbericht 2016/2017 | Annual Report |
2017 | From receptor binding kinetics to signal transduction; a missing link in predicting in vivo drug-action Nederpelt, I.; Kuzikov, M.; Witte, W.E.A. de; Schnider, P.; Tuijt, B.; Gul, S.; IJzerman, A.P.; Lange, E.C.M. de; Heitman, L.H. | Journal Article |
2017 | The function of the AMP-activated protein kinase in vascular remodeling Abdel Malik, R. | Dissertation |
2017 | The G2A receptor (GPR132) contributes to oxaliplatin-induced mechanical pain hypersensitivity Hohmann, S.W.; Angioni, C.; Tunaru, S.; Lee, S.; Woolf, C.J.; Offermanns, S.; Geisslinger, G.; Scholich, K.; Sisignano, M. | Journal Article |
2017 | Generation and characterization of angiogenin mutants as improved effector domains for H22(scFv)-based cytolytic fusion proteins Cremer, C. | Dissertation |
2017 | Generation and Validation of Intracellular Ubiquitin Variant Inhibitors for USP7 and USP10 Zhang, W.; Sartori, M.A.; Makhnevych, T.; Federowicz, K.E.; Dong, X.; Liu, L.; Nim, S.; Dong, A.; Yang, J.; Li, Y.; Haddad, D.; Ernst, A.; Heerding, D.; Tong, Y.; Moffat, J.; Sidhu, S.S. | Journal Article |
2017 | Generation of an artificial human B cell line test system using Transpo-mAb (TM) technology to evaluate the therapeutic efficacy of novel antigen-specific fusion proteins Klose, D.; Woitok, M.; Niesen, J.; Beerli, R.R.; Grawunder, U.; Fischer, R.; Barth, S.; Fendel, R.; Nachreiner, T. | Journal Article |
2017 | Genome Analyses of Insect-associated Microbes Brinkrolf, K.; Heise, P.; Griep, S. | Abstract |
2017 | Genome-wide association and targeted analysis of copy number variants with psoriatic arthritis in German patients Uebe, S.; Ehrlicher, M.; Ekici, A.B.; Behrens, F.; Böhm, B.; Homuth, G.; Schurmann, C.; Völker, U.; Jünger, M.; Nauck, M.; Völzke, H.; Traupe, H.; Krawczak, M.; Burkhardt, H.; Reis, A.; Hüffmeier, U. | Journal Article |
2017 | Geruch und Ernährung. Tl.3: Lebensmittelaromen und ihre Analytik Kotthoff, Matthias; Bücking, Mark | Journal Article |
2017 | GM-CSF in murine psoriasiform dermatitis: Redundant and pathogenic roles uncovered by antibody-induced neutralization and genetic deficiency Scholz, T.; Weigert, A.; Brüne, B.; Sadik, C.D.; Böhm, B.; Burkhardt, H. | Journal Article |
2017 | GPVI and Thromboxane Receptor on Platelets Promote Proinflammatory Macrophage Phenotypes during Cutaneous Inflammation Pierre, S.; Linke, B.; Suo, J.; Tarighi, N.; Turco, D. del; Thomas, D.; Ferreiros, N.; Stegner, D.; Frölich, S.; Sisignano, M.; Santos, S.M. dos; Debruin, N.; Nüsing, R.M.; Deller, T.; Nieswandt, B.; Geisslinger, G.; Scholich, K. | Journal Article |
2017 | Heat shock protein 83 plays pleiotropic roles in embryogenesis, longevity, and fecundity of the pea aphid Acyrthosiphon pisum Will, T.; Schmidtberg, H.; Skaljac, M.; Vilcinskas, A. | Journal Article |
2017 | Herstellung und Charakterisierung von CD13-spezifischen Antikörperderivaten für die diagnostische und therapeutische Anwendung bei hämatologischen und soliden Krebserkrankungen Grieger, E. | Dissertation |
2017 | Heterologous expression of a Streptomyces cyaneus laccase for biomass modification applications Ece, S.; Lambertz, C.; Fischer, R.; Commandeur, U. | Journal Article |
2017 | Hexabromocyclododecane diastereomers in fish and suspended particulate matter from selected European waters-trend monitoring and environmental quality standard compliance Rüdel, Heinz; Müller, Josef; Nowak, Jens; Ricking, Mathias; Klein, Roland; Kotthoff, Matthias | Journal Article |
2017 | A high-content small molecule screen identifies novel inducers of definitive endoderm Korostylev, A.; Mahaddalkar, P.U.; Keminer, O.; Hadian, K.; Schorpp, K.; Gribbon, P.; Lickert, H. | Journal Article |
2017 | A high-throughput expression screening platform to optimize the production of antimicrobial peptides Schreiber, C.; Müller, H.; Birrenbach, O.; Klein, M.; Heerd, D.; Weidner, T.; Salzig, D.; Czermak, P. | Journal Article |
2017 | How Plants Can Contribute to the Supply of Anticancer Compounds Buyel, J.F. | Book Article |
2017 | Human MAP tau based targeted cytolytic fusion proteins Akinrinmade, O.A.; Jordaan, S.; Hristodorov, D.; Mladenov, R.; Mungra, N.; Chetty, S.; Barth, S. | Journal Article |
2017 | Human pregnane X receptor is activated by dibenzazepine carbamate-based inhibitors of constitutive androstane receptor Jeske, J.; Windshügel, B.; Thasler, W.E.; Schwab, M.; Burk, O. | Journal Article |
2017 | Identification, heterologous expression and characterization of a dye-decolorizing peroxidase of Pleurotus sapidus Lauber, C.; Schwarz, T.; Nguyen, Q.K.; Lorenz, P.; Lochnit, G.; Zorn, H. | Journal Article |
2017 | IKKα controls ATG16L1 degradation to prevent ER stress during inflammation Diamanti, M.A.; Gupta, J.; Bennecke, M.; Oliveira, T. de; Ramakrishnan, M.; Braczynski, A.K.; Richter, B.; Beli, P.; Hu, Y.; Saleh, M.; Mittelbronn, M.; Dikic, I.; Greten, F.R. | Journal Article |
2017 | Immunization with the Malaria Diversity-Covering Blood-Stage Vaccine Candiate Plasmodium falciparum Apical Membrane Antigen 1 DiCo in Complex with Its Natural Ligand PfRpm2 Does Not Improve the In Vitro Efficacy Spiegel, H.; Boes, A.; Fendel, R.; Reimann, A.; Schillberg, S.; Fischer, R. | Journal Article |
2017 | The impact of parasites on host insect epigenetics Vilcinskas, A. | Book Article |
2017 | Impact of rituximab in combination with leflunomide and rituximab retreatment with two different dosages on patient-reported outcomes: results from a multicenter randomized placebo controlled investigator initiated clinical trial in active rheumatoid arthritis (AMARA-STUDY) Köhm, M.; Rossmanith, T.; Dauth, S.; Alten, R.; Aringer, M.; Backhaus, M.; Burmester, G.; Feist, E.; Kellner, H.; Krüger, K.; Müller-Ladner, U.; Rubbert-Roth, A.; Tony, H.P.; Wassenberg, S.; Burkhardt, H.; Behrens, F. | Abstract |
2017 | Implementation of new discovery pipelines in industry to access novel lead structures for antibiotics development Glaeser, J.; Zubeil, F.; Toti, L.; Bauer, A.; Vilcinskas, A.; Hammann, P. | Abstract |
2017 | Importance of microorganisms to macroorganisms invasions: Is the essential invisible to the eye? (The Little Prince, A. de Saint-Exupéry, 1943) Amsellem, L.; Brouat, C.; Duron, O.; Porter, S.S.; Vilcinskas, A.; Facon, B. | Book Article |
2017 | Improvement of a fermentation process for the production of two PfAMA1-DiCo-based malaria vaccine candidates in Pichia pastoris Kastilan, R.; Boes, A.; Spiegel, H.; Voepel, N.; Chudobova, I.; Hellwig, S.; Buyel, J.F.; Reimann, A.; Fischer, R. | Journal Article |
2017 | In Vitro Antimicrobial Efficacy of Tobramycin Against Staphylococcus aureus Biofilms in Combination With or Without DNase I and/or Dispersin B: A Preliminary Investigation Waryah, C.B.; Wells, K.; Ulluwishewa, D.; Chen-Tan, N.; Gogoi-Tiwari, J.; Ravensdale, J.; Costantino, P.; Gokcen, A.; Vilcinskas, A.; Wiesner, J.; Mukkur, T. | Journal Article |
2017 | Insect antimicrobial peptides Tonk, M.; Rahnamaeian, R.; Vilcinskas, A. | Abstract |
2017 | Insect Biotechnology Vilcinskas, A. | Abstract |
2017 | The insect-derived antimicrobial peptide metchnikowin targets Fusarium graminearum beta(1,3)-glucanosyltransferase Gel1, which is required for the maintenance of cell wall integrity Moghaddam, M.R.B.; Vilcinskas, A.; Rahnamaeian, M. | Journal Article |
2017 | Integrated computational analysis of genes associated with human hereditary insensitivity to pain Lötsch, J.; Lippmann, C.; Kringel, D.; Ultsch, A. | Journal Article |
2017 | Integrative analysis of DNA methylation and gene expression in butyrate-treated CHO cells Wippermann, A.; Rupp, O.; Brinkrolf, K.; Hoffrogge, R.; Noll, T. | Journal Article |
2017 | Investigation into experimental toxicological properties of plant protection products having a potential link to Parkinson's disease and childhood leukaemia Ockleford, Colin; Adriaanse, Paulien; Berny, Philippe; Brock, Theodorus; Duquesne, Sabine; Grilli, Sandro; Hernandez-Jerez, Antonio F.; Hougaard Bennekou, Susanne; Klein, Michael; Kuhl, Thomas; Laskowski, Ryszard; Machera, Kyriaki; Pelkonen, Olavi; Pieper, Silvia; Stemmer, Michael; Sundh, Ingvar; Teodorovic, Ivana; Tiktak, Aaldrik; Topping, Chris J.; Wolterink, Gerrit; Angeli, Karine; Fritsche, Ellen; Leist, Marcel; Mantovani, Alberto; Menendez, Pablo; Price, Anna; Smith, Rob; Viviani, Barbara; Chiusolo, Arianna; Ruffo, Federica; Terron, Andrea | Journal Article |
2017 | Investigational drugs targeting the prostaglandin E2 signaling pathway for the treatment of inflammatory pain Grösch, S.; Niederberger, E.; Geisslinger, G. | Journal Article |
2017 | Iron handling in tumor-associated macrophages - is there a new role for lipocalin-2? Jung, M.; Weigert, A.; Mertens, C.; Rehwald, C.; Brüne, B. | Journal Article |
2017 | Islet-Expressed CXCL10 Promotes Autoimmune Destruction of Islet Isografts in Mice With Type 1 Diabetes Bender, C.; Christen, S.; Scholich, K.; Bayer, M.; Pfeilschifter, J.M.; Hintermann, E.; Christen, U. | Journal Article |
2017 | Isoprenoid biosynthesis in dandelion latex is enhanced by the overexpression of three key enzymes involved in the mevalonate pathway Pütter, K.M.; Deenen, N. van; Unland, K.; Prüfer, D.; Schulze Gronover, C. | Journal Article |
2017 | Knockdown of genes in the Toll pathway reveals new lethal RNA interference targets for insect pest control Bingsohn, L.; Knorr, E.; Billion, A.; Narva, K.E.; Vilcinskas, A. | Journal Article |
2017 | A Label-Free Continuous Fluorescence-Based Assay for Monitoring Ornithine Decarboxylase Activity with a Synthetic Putrescine Receptor Nilam, M.; Gribbon, P.; Reinshagen, J.; Cordts, K.; Schwedhelm, E.; Nau, W.M.; Hennig, A. | Journal Article |
2017 | The leukotriene B4 receptors BLT1 and BLT2 form an antagonistic sensitizing system in peripheral sensory neurons Zinn, S.; Sisignano, M.; Kern, K.; Pierre, S.; Tunaru, S.; Jordan, H.; Suo, J.; Treutlein, E.M.; Angioni, C.; Ferreiros, N.; Leffler, A.; DeBruin, N.; Offermanns, S.; Geisslinger, G.; Scholich, K. | Journal Article |
2017 | Light spectrum modifies the utilization pattern of energy sources in Pseudomonas sp. DR 5-09 Gharaie, S.; Vaas, L.A.I.; Rosberg, A.K.; Windstam, S.T.; Karlsson, M.E.; Bergstrand, K.-J.; Khalil, S.; Wohanka, W.; Alsanius, B.W. | Journal Article |
2017 | Lipocalin-2 and iron trafficking in the tumor microenvironment Jung, M.; Mertens, C.; Bauer, R.; Rehwald, C.; Brüne, B. | Journal Article |
2017 | Long-term effects of sulfidized silver nanoparticles in sewage sludge on soil microflora Kraas, Marco; Schlich, Karsten; Knopf, Burkhard; Wege, Franziska; Kägi, Ralf; Terytze, Konstantin; Hund-Rinke, Kerstin | Journal Article |
2017 | Machine-learned cluster identification in high-dimensional data Ultsch, A.; Lötsch, J. | Journal Article |
2017 | Machine-learned data structures of lipid marker serum concentrations in multiple sclerosis patients differ from those in healthy subjects Lötsch, J.; Thrun, M.; Lerch, F.; Brunkhorst, R.; Schiffmann, S.; Thomas, D.; Tegder, I.; Geisslinger, G.; Ultsch, A. | Journal Article |
2017 | Macrophage-derived lipocalin-2 transports iron in the tumor microenvironment Mertens, C.; Mora, J.; Ören, B.; Grein, S.; Winslow, S.; Scholich, K.; Weigert, A.; Malmström, P.; Forsare, C.; Fernö, M.; Schmid, T.; Brüne, B.; Jung, M. | Journal Article |
2017 | Malaria immunoassemblins Edgü, G. | Dissertation |
2017 | Mannheimia haemolytica growth and leukotoxin production for vaccine manufacturing - a bioprocess review Oppermann, T.; Busse, N.; Czermak, P. | Journal Article |
2017 | The market for diagnostic devices in the food industry Bücking, M.; Hoogland, H.; Lelieveld, H. | Book Article |
2017 | The medical potential of antimicrobial peptides from insects Tonk, M.; Vilcinskas, A. | Journal Article |
2017 | Metabolism and pharmacokinetics of zearalenone following oral and intravenous administration in juvenile female pigs Fleck, S.C.; Churchwell, M.I.; Doerge, D.R. | Journal Article |
2017 | Methoxylated 2'-hydroxychalcones as antiparasitic hit compounds Borsari, C.; Santarem, N.; Torrado, J.; Olías, A.I.; Corral, M.J.; Baptista, C.; Gul, S.; Wolf, M.; Kuzikov, M.; Ellinger, B.; Witt, G.; Gribbon, P.; Reinshagen, J.; Linciano, P.; Tait, A.; Costantino, L.; Freitas-Junior, L.H.; Moraes, C.B.; Bruno dos Santos, P.; Alcântara, L.M.; Franco, C.H.; Bertolacini, C.D.; Fontana, V.; Tejera Nevado, P.; Clos, J.; Alunda, J.M.; Cordeiro-da-Silva, A.; Ferrari, S.; Costi, M.P. | Journal Article |
2017 | Michael acceptor containing drugs are a novel class of 5-lipoxygenase inhibitor targeting the surface cysteines C416 and C418 Maucher, I.V.; Rühl, M.; Kretschmer, S.B.M.; Hofmann, B.; Kühn, B.; Fettel, J.; Vogel, A.; Flügel, K.-T.; Manolikakes, G.; Hellmuth, N.; Häfner, A.-K.; Golghalyani, V.; Ball, A.K.; Piesche, M.; Matrone, C.; Geisslinger, G.; Parnham, M.J.; Karas, M.; Steinhilber, D.; Roos, J.; Maier, T.J. | Journal Article |
2017 | Michaelreaktive Verbindungen als neue Klasse der 5-Lipoxygenase-Inhibitoren Maucher, I. | Dissertation |
2017 | Microcarrier choice and bead-to-bead transfer for human mesenchymal stem cells in serum-containing and chemically defined media Leber, J.; Barekzai, J.; Blumenstock, M.; Pospisil, B.; Salzig, D.; Czermak, P. | Journal Article |
2017 | Microfluidic coagulation assay for monitoring anticoagulant therapy in acute stroke patients Bluecher, A.; Meyer dos Santos, S.; Ferreiros, N.; Labocha, S.; Meyer dos Santos, I.M.R.; Picard-Willems, B.; Harder, S.; Singer, O.C. | Journal Article |
2017 | Mitochondrial composition and function under the control of hypoxia Fuhrmann, D.C.; Brüne, B. | Journal Article |
2017 | Modeling the design and operational mode of a continuous membrane reactor for enzymatic lignin modification Busse, N.; Kraume, M.; Czermak, P. | Journal Article |
2017 | Monoclonal Antibodies in Preclinical EAE Models of Multiple Sclerosis Schmitz, K.; Geisslinger, G.; Tegeder, I. | Journal Article |
2017 | Multi-target malaria vaccines against the sexual stage of Plasmodium falciparum Beiß, V. | Dissertation |
2017 | Multitarget‐Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H3R Antagonism for Neurodegenerative Diseases Bautista‐Aguilera, O.M.; Hagenow, S.; Palomino‐Antolin, A.; Farré‐Alins, V.; Ismaili, L.; Joffrin, P.-L.; Jimeno, M.L.; Soukup, O.; Janočková, J.; Kalinowsky, L.; Proschak, E.; Iriepa, I.; Moraleda, I.; Schwed, J.S.; Martínez, A.R.; López‐Muñoz, F.; Chioua, M.; Egea, J.; Ramsay, R.R.; Marco‐Contelles, J.; Stark, H. | Journal Article |
2017 | Myc binding protein 2 suppresses M2‐like phenotypes in macrophages during zymosan‐induced inflammation in mice Pierre, S.; Zhang, D.D.; Suo, J.; Kern, K.; Tarighi, N.; Scholich, K. | Journal Article |
2017 | Nanomaterials to microplastics: Swings and roundabouts Scott-Fordsmand, Janeck J.; Navas, Jose Maria; Hund-Rinke, Kerstin; Nowack, Bernd; Amorim, Monica J.B. | Journal Article |
2017 | Naturkautschuk aus Russischem Löwenzahn Fischer, R.; Schulze Gronover, C.; Prüfer, D. | Book Article |
2017 | Ein neuartiger Assay zur Messung chemotaktischer Migration in Echtzeit O’Clair, L.; Ellinger, B.; Kalmer, M.; Szybut, C.; Borsetti, Y. | Journal Article |
2017 | New tools for maggot debridement therapy research Baumann, A. | Dissertation |
2017 | Next-generation sequencing of the human TRPV1 gene and the regulating co-players LTB4R and LTB4R2 based on a custom AmpliSeq (TM) panel Kringel, D.; Sisignano, M.; Zinn, S.; Lötsch, J. | Journal Article |
2017 | Non-invasive raman spectroscopy and quantitative real-time PCR distinguish among undifferentiated human mesenchymal stem cells and redifferentiated nucleus pulposus cells and chondrocytes In Vitro Ehlicke, F.; Köster, N.; Salzig, D.; Czermak, P. | Journal Article |
2017 | Nonacidic Farnesoid X Receptor Modulators Flesch, D.; Cheung, S.Y.; Schmidt, J.; Gabler, M.; Heitel, P.; Kramer, J.; Kaiser, A.; Hartmann, M.; Lindner, M.; Lüddens-Dämgen, K.; Heering, J.; Lamers, C.; Lüddens, H.; Wurglics, M.; Proschak, E.; Schubert-Zsilavecz, M.; Merk, D. | Journal Article |
2017 | Novel approaches to identify small molecules modulating E.coli TolC protein function Gilardi, A. | Dissertation |
2017 | Novel PSCA targeting scFv-fusion proteins for diagnosis and immunotherapy of prostate cancer Kessler, C.; Pardo, A.; Tur, M.K.; Gattenlöhner, S.; Fischer, R.; Kolberg, K.; Barth, S. | Journal Article |
2017 | Nrf2, the master regulator of anti-oxidative responses Vomund, S.; Schäfer, A.; Parnham, M.J.; Brüne, B.; Knethen, A. von | Journal Article |
2017 | Nutzung von Biokohlesubstraten zur Wiederaufforstung von Windwurfflächen und auf Weihnachtsbaumkulturen Drabkin, Dimitri : Terytze, Konstantin; Schütt, Brigitta; Stevens, Albert-Dieter; Weinfurtner, Karlheinz | Dissertation |
2017 | On-line monitoring tools for food processing Bücking, Mark; Kotthoff, Matthias | Journal Article |
2017 | Ongoing liver inflammation in patients with chronic hepatitis C and sustained virological response Welsch, C.; Efinger, M.; Wagner, M. von; Herrmann, E.; Zeuzem, S.; Welzel, T.M.; Lange, C.M. | Electronic Publication, Journal Article |
2017 | OP0202 Efficacy and safety of tofacitinib, an oral janus kinase inhibitor, in patients with active psoriatic arthritis and an inadequate response to tumour necrosis factor inhibitors Gladman, D.D.; Rigby, W.F.C.; Azevedo, V.F.; Behrens, F.; Blanco, R.; Kaszuba, A.; Kudlacz, E.; Wang, C.; Menon, S.; Hendrikx, T.; Kanik, K.S. | Abstract |
2017 | Opportunities and Challenges for Fatty Acid Mimetics in Drug Discovery Proschak, E.; Heitel, P.; Kalinowsky, L.; Merk, D. | Journal Article |
2017 | Optimal permeate flux for an enzymatic oxidation of technical lignins in a membrane reactor Busse, N.; Kraume, M.; Czermak, P. | Journal Article |
2017 | Optimized expression of the antimicrobial protein Gloverin from Galleria mellonella using stably transformed Drosophila melanogaster S2 cells Zitzmann, J.; Weidner, T.; Czermak, P. | Journal Article |
2017 | OR2M3: A highly specific and narrowly tuned human odorant receptor for the sensitive detection of onion key food odorant 3-Mercapto-2-methylpentan-1-ol Noe, Franziska; Polster, Johannes; Geithe, Christiane; Kotthoff, Matthias; Schieberle, Peter; Krautwurst, Dietmar | Journal Article |
2017 | Orally delivered scorpion antimicrobial peptides exhibit activity against Pea Aphid (Acyrthosiphon pisum) and its bacterial symbionts Luna-Ramirez, K.; Skaljac, M.; Grotmann, J.; Kirfel, P.; Vilcinskas, A. | Journal Article |
2017 | Oxidized lipids in the treatment of chronic or neuropathic pain Sisignano, Marco; Geisslinger, Gerd; Parnham, Michael John | Patent |
2017 | Parasite prevalence in Mycobacterium spp. Infected dairy goats in the region of Murcia (south-east Spain) Carrau, T.; Garijo, M.M.; Martínez-Carrasco, C.; Pérez, D.; Silva, L.M.R.; Taubert, A.; Hermosilla, C.; Ybáñez, R.R. de | Journal Article |
2017 | Pesticide exposure assessment for surface waters in the EU. Pt.2: Determination of statistically based run-off and drainage scenarios for Germany Bach, Martin; Diesner, Mirjam; Großmann, Dietlinde; Guerniche, Djamal; Hommen, Udo; Klein, Michael; Kubiak, Roland; Müller, Alexandra; Preuss, Thomas G.; Priegnitz, Jan; Reichenberger, Stefan; Thomas, Kai; Trapp, Matthias | Journal Article |
2017 | The polysialic acid mimetics idarubicin and irinotecan stimulate neuronal survival and neurite outgrowth and signal via protein kinase C Loers, G.; Astafiev, S.; Hapiak, Y.; Saini, V.; Mishra, B.; Gul, S.; Kaur, G.; Schachner, M.; Theis, T. | Journal Article |
2017 | Porcellio scaber als Testorganismus für Bioakkumulationsstudien Kampe, S. | Dissertation |
2017 | PP2A-B′ holoenzyme substrate recognition, regulation and role in cytokinesis Wu, C.-G.; Chen, H.; Guo, F.; Yadav, V.K.; McIlwain, S.J.; Rowse, M.; Choudhary, A.; Lin, Z.; Li, Y.; Gu, T.; Zheng, A.; Xu, Q.; Lee, W.; Resch, E.; Johnson, B.; Day, J.; Ge, Y.; Ong, I.M.; Burkard, M.E.; Ivarsson, Y.; Xing, Y. | Journal Article |
2017 | PPARgamma as a putative stress marker in T cells following kidney transplantation Aghajaanpour, R.; Brenneis, M.; Köhler, N.; Knape, T.; Büttner, S.; Kuchler, L.; Parnham, M.J.; Bruene, B.; Hauser, I.A.; Knethen, A. von | Abstract |
2017 | Prediction of persistent post-surgery pain by preoperative cold pain sensitivity: Biomarker development with machine-learning-derived analysis Lötsch, J.; Ultsch, A.; Kalso, E. | Journal Article |
2017 | Probiotic Enterococcus mundtii isolate protects the model insect Tribolium castaneum against Bacillus thuringiensis Grau, T.; Vilcinskas, A.; Joop, G. | Journal Article |
2017 | Process engineering of insect cell expression systems Weidner, T.; Zitzmann, J.; Druzinec, D.; Czermak, P. | Abstract |
2017 | Production of Functional Anti-Ebola Antibodies in Pichia pastoris Purcell, O.; Opdensteinen, P.; Chen, W.; Lowenhaupt, K.; Brown, A.; Hermann, M.; Cao, J.; Tenhaef, N.; Kallweit, E.; Kastilan, R.; Sinskey, A.J.; Perez-Pinera, P.; Buyel, J.F.; Lu, T.K. | Journal Article |
2017 | Progress does not just come in giant leaps: adapting techniques for the study of inflammation to novel applications Parnham, M.J. | Journal Article |
2017 | Proteasomal and Autophagic Degradation Systems Dikic, I. | Journal Article |
2017 | Psoriasisarthritis Übersicht medikamentöser Therapieoptionen und Anwendungsbesonderheiten Behrens, F.; Thaci, D.; Wollenhaupt, J.; Krüger, K. | Journal Article |
2017 | Psoriasisarthritis. Aktuelle therapeutische Standards Köhm, M.; Behrens, F. | Journal Article |
2017 | Quantitative sensory testing response patterns to capsaicin- and ultraviolet-B–induced local skin hypersensitization in healthy subjects Lötsch, J.; Geisslinger, G.; Heinemann, S.; Lerch, F.; Oertel, B.G.; Ultsch, A. | Journal Article |
2017 | R-flurbiprofen traps prostaglandins within cells by inhibition of multidrug resistance-associated protein-4 Wobst, I.; Ebert, L.; Birod, K.; Wegner, M.-S.; Hoffmann, M.; Thomas, D.; Angioni, C.; Parnham, M.J.; Steinhilber, D.; Tegeder, I.; Geisslinger, G.; Grösch, S. | Journal Article |
2017 | Rab7 - A novel redox target that modulates inflammatory pain processing Kallenborn-Gerhardt, W.; Möser, C.V.; Lorenz, J.E.; Steger, M.; Heidler, J.; Scheving, R.; Petersen, J.; Kennel, L.; Flauaus, C.; Lu, R.; Edinger, A.L.; Tegeder, I.; Geisslinger, G.; Heide, H.; Wittig, I.; Schmidtko, A. | Journal Article |
2017 | Rapid establishment of the European Bank for induced Pluripotent Stem Cells (EBiSC) - the Hot Start experience Sousa, P.A. de; Steeg, R.; Wachter, E.; Bruce, K.; King, J.; Hoeve, M.; Khadun, S.; McConnachie, G.; Holder, J.; Kurtz, A.; Seltmann, S.; Dewender, J.; Reimann, S.; Stacey, G.; O'Shea, O.; Chapman, C.; Healy, L.; Zimmermann, H.; Bolton, B.; Rawat, T.; Atkin, I.; Veiga, A.; Kuebler, B.; Serano, B.M.; Saric, T.; Hescheler, J.; Brüstle, O.; Peitz, M.; Thiele, C.; Geijsen, N.; Holst, B.; Clausen, C.; Lako, M.; Armstrong, L.; Gupta, S.K.; Kvist, A.J.; Hicks, R.; Jonebring, A.; Brolen, G.; Ebneth, A.; Cabrera-Socorro, A.; Foerch, P.; Geraerts, M.; Stummann, T.C.; Harmon, S.; George, C.; Streeter, I.; Clarke, L.; Parkinson, H.; Harrison, P.W.; Faulconbridge, A.; Cherubin, L.; Burdett, T.; Trigueros, C.; Patel, M.J.; Lucas, C.; Hardy, B.; Predan, R.; Dokler, J.; Brajnik, M.; Keminer, O.; Pless, O.; Gribbon, P.; Claussen, C.; Ringwald, A.; Kreisel, B.; Courtney, A.; Allsopp, T.E. | Journal Article |
2017 | Reassessment of inclusion body-based production as a versatile opportunity for difficult-to-express recombinant proteins Hoffmann, D.; Ebrahimi, M.; Gerlach, D.; Salzig, D.; Czermak, P. | Journal Article |
2017 | Recommended approaches to the scientific evaluation of ecotoxicological hazards and risks of endocrine-active substances Matthiessen, P.; Ankley, G.T.; Biever, R.C.; Bjerregaard, P.; Borgert, C.; Brugger, K.; Blankinship, A.; Chambers, J.; Coady, K.K.; Constantine, L.; Dang, Z.; Denslow, N.D.; Dreier, D.A.; Dungey, S.; Gray, L.E.; Gross, M.; Guiney, P.D.; Hecker, M.; Holbech, H.; Iguchi, T.; Kadlec, S.; Karouna-Renier, N.K.; Katsiadaki, I.; Kawashima, Y.; Kloas, W.; Krueger, H.; Kumar, A.; Lagadic, L.; Leopold, A.; Levine, S.L.; Maack, G.; Marty, S.; Meador, J.; Mihaich, E.; Odum, J.; Ortego, L.; Parrott, J.; Pickford, D.; Roberts, M.; Schaefers, C.; Schwarz, T.; Solomon, K.; Verslycke, T.; Weltje, L.; Wheeler, J.R.; Williams, M.; Wolf, J.C.; Yamazaki, K. | Journal Article |
2017 | Reprint of "Multiphase mixing characteristics in a microcarrier-based stirred tank bioreactor suitable for human mesenchymal stem cell expansion" Grein, T.A.; Leber, J.; Blumenstock, M.; Petry, F.; Weidner, T.; Salzig, D.; Czermak, P. | Journal Article |
2017 | The role of PGE2 in alveolar epithelial and lung microvascular endothelial crosstalk Bärnthaler, T.; Maric, J.; Platzer, W.; Konya, V.; Theiler, A.; Hasenöhrl, C.; Gottschalk, B.; Trautmann, S.; Schreiber, Y.; Graier, W.F.; Schicho, R.; Marsche, G.; Olschewski, A.; Thomas, D.; Schuligoi, R.; Heinemann, A. | Journal Article |
2017 | S1P provokes tumor lymphangiogenesis via macrophage-derived mediators such as IL-1β or Lipocalin-2 Syed, S.N.; Jung, M.; Weigert, A.; Brüne, B. | Journal Article |
2017 | S1PR1 on tumor-associated macrophages promotes lymphangiogenesis and metastasis via NLRP3/IL-1β Weichand, B.; Popp, R.; Dziumbla, S.; Mora, J.; Strack, E.; Elwakeel, E.; Frank, A.-C.; Scholich, K.; Pierre, S.; Syed, S.N.; Olesch, C.; Ringleb, J.; Ören, B.; Döring, C.; Savai, R.; Jung, M.; Knethen, A. von; Levkau, B.; Fleming, I.; Weigert, A.; Brüne, B. | Journal Article |
2017 | SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia Schneider, C.; Oellerich, T.; Baldauf, H.-M.; Schwarz, S.-M.; Thomas, D.; Flick, R.; Bohnenberger, H.; Kaderali, L.; Stegmann, L.; Cremer, A.; Martin, M.; Lohmeyer, J.; Michaelis, M.; Hornung, V.; Schliemann, C.; Berdel, W.E.; Hartmann, W.; Wardelmann, E.; Comoglio, F.; Hansmann, M.L.; Yakunin, A.F.; Geisslinger, G.; Ströbel, P.; Ferreiros, N.; Serve, H.; Keppler, O.T.; Cinatl, J. | Journal Article |
2017 | Scientific Opinion addressing the state of the science on risk assessment of plant protection products for in-soil organisms Ockleford, Colin; Adriaanse, Paulien; Berny, Philippe; Brock, Theodorus; Duquesne, Sabine; Grilli, Sandro; Hernandez-Jerez, Antonio F.; Hougaard Bennekou, Susanne; Klein, Michael; Kuhl, Thomas; Laskowski, Ryszard; Machera, Kyriaki; Pelkonen, Olavi; Pieper, Silvia; Stemmer, Michael; Sundh, Ingvar; Teodorovic, Ivana; Tiktak, Aaldrik; Topping, Chris J.; Wolterink, Gerrit; Craig, Peter; de Jong, Frank; Manachini, Barbara; Sousa, Paulo; Swarowsky, Klaus; Auteri, Domenica; Arena, Maria; Smith, Rob | Journal Article |
2017 | Scientific Opinion of the PPR Panel on the follow-up of the findings of the External Scientific Report 'Literature review of epidemiological studies linking exposure to pesticides and health effects' Ockleford, Colin; Adriaanse, Paulien; Berny, Philippe; Brock, Theodorus; Duquesne, Sabine; Grilli, Sandro; Hernandez-Jerez, Antonio F.; Hougaard Bennekou, Susanne; Klein, Michael; Kuhl, Thomas; Laskowski, Ryszard; Machera, Kyriaki; Pelkonen, Olavi; Pieper, Silvia; Stemmer, Michael; Sundh, Ingvar; Teodorovic, Ivana; Tiktak, Aaldrik; Topping, Chris J.; Wolterink, Gerrit; Bottai, Matteo; Halldorsson, Thorhallur; Hamey, Paul; Rambourg, Marie-Odile; Tzoulaki, Ioanna; Marques, Daniele Court; Crivellente, Federica; Smith, Rob; Deluyker, Hubert | Journal Article |
2017 | Screening different host cell lines for the dynamic production of measles virus Grein, T.A.; Schwebel, F.; Kress, M.; Loewe, D.; Dieken, H.; Salzig, D.; Weidner, T.; Czermak, P. | Journal Article |
2017 | A screening strategy for the discovery of drugs that reduce C/EBPβ-LIP translation with potential calorie restriction mimetic properties Zaini, M.A.; Müller, C.; Ackermann, T.; Reinshagen, J.; Kortman, G.; Pless, O.; Calkhoven, C.F. | Journal Article |
2017 | The selective antifungal activity of Drosophila melanogaster metchnikowin reflects the species-dependent inhibition of succinate-coenzyme Q reductase Moghaddam, M.-R.B.; Gross, T.; Becker, A.; Vilcinskas, A.; Rahnamaeian, M. | Journal Article |
2017 | Short-term molecular and physiological responses to heat stress in neritic copepods Acartia tonsa and Eurytemora affinis Rahlff, J.; Peters, J.; Moyano, M.; Pless, O.; Claussen, C.; Peck, M.A. | Journal Article |
2017 | Site-specific inhibition of the small ubiquitin-like modifier (SUMO)-conjugating enzyme Ubc9 selectively impairs SUMO chain formation Wiechmann, S.; Gärtner, A.; Kniss, A.; Stengl, A.; Behrends, C.; Rogov, V.V.; Rodriguez, M.S.; Dötsch, V.; Müller, S.; Ernst, A. | Journal Article |
2017 | Smart systems for food quality and safety Bücking, M.; Hengse, A.; Grüger, H.; Schulte, H. | Book Article |
2017 | SNAP-tag technology. A promising tool for ex vivo immunophenotyping Choudhary, S.; Barth, S.; Verma, R.S. | Journal Article |
2017 | Sphingosine Kinase-2 Deficiency Ameliorates Kidney Fibrosis by Up-Regulating Smad7 in a Mouse Model of Unilateral Ureteral Obstruction Schwalm, S.; Beyer, S.; Frey, H.; Haceni, R.; Grammatikos, G.; Thomas, D.; Geisslinger, G.; Schaefer, L.; Huwiler, A.; Pfeilschifter, J. | Journal Article |
2017 | A standardised frankincense extract reduces disease activity in relapsing-remitting multiple sclerosis (the SABA phase IIa trial) Stürner, K.H.; Stellmann, J.-P.; Dörr, J.; Paul, F.; Friede, T.; Schammler, S.; Reinhardt, S.; Gellissen, S.; Weissflog, G.; Faizy, T.D.; Werz, O.; Fleischer, S.; Vaas, L.A.I.; Herrmann, F.; Pless, O.; Martin, R.; Heesen, C. | Journal Article |
2017 | Strategies for the construction of insect P450 fusion enzymes Talmann, L.; Wiesner, J.; Vilcinskas, A. | Journal Article |
2017 | Structural and functional characterization of a ubiquitin variant engineered for tight and specific binding to an alpha‐helical ubiquitin interacting motif Manczyk, N.; Yates, B.P.; Veggiani, G.; Ernst, A.; Sicheri, F.; Sidhu, S.S. | Journal Article |
2017 | Sustainable farming of the mealworm Tenebrio molitor for the production of food and feed Grau, T.; Vilcinskas, A.; Joop, G. | Journal Article |
2017 | Svetamycins A-G, unusual piperazic acid-containing peptides from Streptomyces sp. Dardić, D.; Lauro, G.; Bifulco, G.; Laboudie, P.; Sakhaii, P.; Bauer, A.; Vilcinskas, A.; Hammann, P.E.; Plaza, A. | Journal Article |
2017 | Synergistic Efficacy of Aedes aegypti Antimicrobial Peptide Cecropin A2 and Tetracycline against Pseudomonas aeruginosa Zheng, Z.; Tharmalingam, N.; Liu, Q.; Jayamani, E.; Kim, W.; Fuchs, B.B.; Zhang, R.; Vilcinskas, A.; Mylonakis, E. | Journal Article |
2017 | Synthesis and Biological Activity of Octaketides from the Cytosporone Family Delius, M. von; Le, C.M.; Ellinger, B.; Kuzikov, M.; Gul, S.; Dong, V.M. | Journal Article |
2017 | The target residence time of antihistamines determines their antagonism of the G protein-coupled histamine H1 receptor Bosma, R.; Witt, G.; Vaas, L.A.I.; Josimovic, I.; Gribbon, P.; Vischer, H.F.; Gul, S.; Leurs, R. | Journal Article |
2017 | Taxol® Biosynthesis and Production McElroy, C.; Jennewein, S. | Book Article |
2017 | Temporal dynamics of whole body residues of the neonicotinoid insecticide imidacloprid in live or dead honeybees Schott, M.; Bischoff, G.; Eichner, G.; Vilcinskas, A.; Büchler, R.; Meixner, M.D.; Brandt, A. | Journal Article |
2017 | TGFβ/SMAD signalling modulates MLL and MLL-AF4 mediated 5-lipoxygenase promoter activation Saul, M.J.; Groher, F.; Hegewald, A.B.; Müller-McNicoll, M.; Marschalek, R.; Suess, B.; Steinhilber, D. | Journal Article |
2017 | THP-1 and human peripheral blood mononuclear cell-derived macrophages differ in their capacity to polarize in vitro Shiratori, H.; Feinweber, C.; Luckhardt, S.; Linke, B.; Resch, E.; Geisslinger, G.; Weigert, A.; Parnham, M.J. | Journal Article |
2017 | Tofacitinib for psoriatic arthritis in patients with an inadequate response to TNF inhibitors Gladman, D.; Rigby, W.; Azevedo, V.F.; Behrens, F.; Blanco, R.; Kaszuba, A.; Kudlacz, E.; Wang, C.; Menon, S.; Hendrikx, T.; Kanik, K.S. | Journal Article |
2017 | Toward Discovery of Novel Microtubule Targeting Agents Berges, N.; Arens, K.; Kreusch, V.; Fischer, R.; Fiore, S. di | Journal Article |
2017 | Towards the review of the European Union Water Framework Directive: Recommendations for more efficient assessment and management of chemical contamination in European surface water resources Brack, Werner; Dulio, Valeria; Ågerstrand, Marlene; Allan, Ian; Altenburger, Rolf; Brinkmann, Markus; Bunke, Dirk; Burgess, Robert M.; Cousins, Ian; Escher, Beate I.; Hernández, Félix J.; Hewitt, L. Mark; Hilscherová, Klára; Hollender, Juliane; Hollert, Henner; Kase, Robert; Klauer, Bernd; Lindim, Claudia; Herráez, David López; Miège, Cécil; Munthe, John; O'Toole, Simon; Posthuma, Leo; Rüdel, Heinz; Schäfer, Ralf B.; Sengl, Manfred; Smedes, Foppe; Meent, Dik van de; Brink, Paul J. van den; Gils, Jos van; Wezel, Annemarie P. van; Vethaak, A. Dick; Vermeirssen, Etienne; Ohe, Peter C. von der; Vrana, Branislav | Journal Article |
2017 | Ubiquitylation of p62/sequestosome1 activates its autophagy receptor function and controls selective autophagy upon ubiquitin stress Peng, H.; Yang, J.; Li, G.; You, Q.; Han, W.; Li, T.; Gao, D.; Xie, X.; Lee, B.-H.; Du, J.; Hou, J.; Zhang, T.; Rao, H.; Huang, Y.; Li, Q.; Zeng, R.; Hui, L.; Wang, H.; Xia, Q.; Zhang, X.; He, Y.; Komatsu, M.; Dikic, Y.; Finley, D.; Hu, R. | Journal Article |
2017 | Understanding critical aspects of aphid survival and developing strategies for their control Skaljac, M.; Luna-Ramirez, K.; Kirfel, P.; Grotmann, J.; Vilcinskas, A. | Abstract |
2017 | Urate Oxidase produced by Lucilia sericata medical maggots is localized in Malpighian tubes and facilitates allantoin production Baumann, A.; Skaljac, M.; Lehmann, R.; Vilcinskas, A.; Franta, Z. | Journal Article |
2017 | Using a Standardized Clinical Quantitative Sensory Testing Battery to Judge the Clinical Relevance of Sensory Differences Between Adjacent Body Areas Dimova, V.; Oertel, B.G.; Lötsch, J. | Journal Article |
2017 | Ustekinumab for the treatment of psoriatic arthritis – results of the first interim analysis of the non-interventional study sustain Wendler, J.; Schwarze, I.; Schwenke, H.; Behrens, J.; Gruppe, T.; Behrens, F. | Abstract |
2017 | Validation of the OECD reproduction test guideline with the New Zealand mudsnail Potamopyrgus antipodarum using trenbolone and prochloraz Geiß, Cornelia; Ruppert, Katharina; Askem, Clare; Barroso, Carlos; Faber, Daniel; Ducrot, Virginie; Holbech, Henrik; Hutchinson, Thomas H.; Kajankari, Paula; Lund Kinnberg, Karin; Lagadic, Laurent; Matthiessen, Peter; Morris, Steve; Neiman, Maurine; Penttinen, Olli-Pekka; Sanchez-Marin, Paula; Teigeler, Matthias; Weltje, Lennart; Oehlmann, Jörg | Journal Article |
2017 | Very-large-scale production of antibodies in plants: The biologization of manufacturing Buyel, J.F.; Twyman, R.M.; Fischer, R. | Journal Article |
2017 | Vitamin D Supplementation Enhances C18(dihydro)ceramide Levels in Type 2 Diabetes Patients Koch, A.; Grammatikos, G.; Trautmann, S.; Schreiber, Y.; Thomas, D.; Bruns, F.; Pfeilschifter, J.; Badenhoop, K.; Penna-Martinez, M. | Journal Article |
2017 | Xeroderma pigmentosum group C protein interacts with histones Kakumu, E.; Nakanishi, S.; Shiratori, H.M.; Kato, A.; Kobayashi, W.; Machida, S.; Yasuda, T.; Adachi, N.; Saito, N.; Ikura, T.; Kurumizaka, H.; Kimura, H.; Yokoi, M.; Sakai, W.; Sugasawa, K. | Journal Article |
2017 | Zelluläre Analyse des Histamin-H4-Rezeptors in humanen myeloiden Zellen Capelo, R. | Dissertation |
2017 | Zielgerichtete Eliminierung autoreaktiver B-Lymphozyten mithilfe Antigen-basierter Fusionsproteine Klose, D. | Dissertation |
2017 | Zytopenien Kneitz, C.; Atta, J.; Burkhardt, H. | Journal Article |
2017 | Der Einfluss von Antikörper vermittelter GM-CSF-Neutralisierung und genetischer GM-CSF-Defizienz auf die IMQ-induzierte psoriasiforme Dermatitis Scholz, T. | Dissertation |
2017 | Functional characterization of the rubber transferase activator and analysis of the relationship between natural rubber and inulin metabolism in dandelion Stolze, A.-K. | Dissertation |
2017 | Funktion der Leukotrien B4 Rezeptoren bei der peripheren nozizeptiven Sensibilisierung Zinn, S. | Dissertation |
2017 | Heterologe Expression eines von Galleria mellonella abgeleiteten antimikrobiellen Peptids (AMP) mittels insektenzellbasierter Expressionssysteme Druzinec, D. | Dissertation |
2017 | Oxidierte Lipide bei Chemotherapie-induzierten neuropathischen Schmerzen Hohmann, S. | Dissertation |
2017 | Role of LCN-2 from tumor-associated macrophages as an alternative iron transporter during tumor growth Mertens, C. | Dissertation |
2017 | The role of sphingosine-1-phosphate receptor 4 in tumor-associated inflammation Olesch, C. | Dissertation |
2016 | Abuse-Deterrent Opioid Formulations: Pharmacokinetic and Pharmacodynamic Considerations Walter, C.; Knothe, C.; Lötsch, J. | Journal Article |
2016 | Achievement of individual important response measured by Das28dcrit in active rheumatoid arthritis when treated with tocilizumab Behrens, F.; Köhm, M.; Hofmann, M.; Fliedner, G.; Specker, C.; Burkhardt, H. | Abstract |
2016 | Acquired immune responses to three malaria vaccine candidates and their relationship to invasion inhibition in two populations naturally exposed to malaria Addai-Mensah, O.; Seidel, M.; Amidu, N.; Maskus, DJ.; Kapelski, S.; Breuer, G.; Franken, C.; Owusu-Dabo, E.; Frempong, M.; Rakotozandrindrainy, R.; Schinkel, H.; Reimann, A.; Klockenbring, T.; Barth, S.; Fischer, R.; Fendel, R. | Journal Article |
2016 | Alpha-methylacyl-CoA racemase deletion has mutually counteracting effects on T-cell responses, associated with unchanged course of EAE Tafferner, N.; Barthelmes, J.; Eberle, M.; Ulshöfer, T.; Henke, M.; deBruin, N.; Mayer, C.A.; Foerch, C.; Geisslinger, G.; Parnham, M.J.; Schiffmann, S. | Journal Article |
2016 | Alternative exon usage creates novel transcript variants of tumor suppressor SHREW-1 gene with differential tissue expression profile Klemmt, P.A.B.; Resch, E.; Smyrek, I.; Engels, K.; Stelzer, E.H.K.; Starzinski-Powitz, A. | Journal Article |
2016 | AMPK-independent inhibition of human macrophage ER stress response by AICAR Boß, M.; Newbatt, Y.; Gupta, S.; Collins, I.; Brüne, B.; Namgaladze, D. | Journal Article |
2016 | Analysis of the dose-dependent stage-specific in vitro efficacy of a multi-stage malaria vaccine candidate cocktail Boes, A.; Spiegel, H.; Kastilan, R.; Bethke, S.; Voepel, N.; Chudobova, I.; Bolscher, J.M.; Dechering, K.J.; Fendel, R.; Buyel, J.F.; Reimann, A.; Schillberg, S.; Fischer, R. | Journal Article |
2016 | Analytical method development for the determination of eight biocides in various environmental compartments and application for monitoring purposes Wluka, A.-K.; Rüdel, H.; Pohl, K.; Schwarzbauer, J. | Journal Article |
2016 | Anti-citrullinated protein antibodies are linked to erosive disease in an observational study of patients with psoriatic arthritis Behrens, F.; Koehm, M.; Thaci, D.; Gnann, H.; Greger, G.; Wittig, B.M.; Burkhardt, H. | Journal Article |
2016 | Anti-Parasitic Complexes Fendel, Rolf; Kapelski, Stephanie; Barth, Stefan; Fischer, Rainer; Reimann, Andreas | Patent |
2016 | Anti-plasmodium parasite antibodies Fischer, Rainer; Reimann, Andreas; Maskus, Dominika Jacqueline; Fendel, Rolf; Klockenbring, Torsten | Patent |
2016 | Antibody-Mediated Pathogen Resistance in Plants Peschen, D.; Schillberg, S.; Fischer, R. | Book Article |
2016 | Antiplasmodial activity is an ancient and conserved feature of tick defensins Cabezas-Cruz, A.; Tonk, M.; Bouchut, A.; Pierrot, C.; Pierce, R.J.; Kotsyfakis, M.; Rahnamaeian, M.; Vilcinskas, A.; Khalife, J.; Valdés, J.J. | Journal Article |
2016 | Anwendung von organischen Düngern und organischen Reststoffen in der Landwirtschaft Wiesler, F.; Hund-Rinke, K.; Gäth, S.; George, E.; Greef, J.M.; Hölzle, L.E.; Holz, F.; Hülsbergen, K.-J.; Pfeil, R.; Severin, K.; Frede, H.-G.; Blum, B.; Schenkel, H.; Horst, W.; Dittert, K.; Ebertseder, T.; Osterburg, B.; Philipp, W.; Pietsch, M. | Journal Article |
2016 | Apoptosis-induced tolerance. Role of the novel cytokine IL-38 Mora, J.; Han, Y.; Wittig, I.; Putyrski, M.; Ernst, A.; Brüne, B.; Weigert, A. | Abstract |
2016 | Arc/Arg3.1 governs inflammatory dendritic cell migration from the skin and thereby controls T cell activation Ufer, F.; Vargas, P.; Engler, J.B.; Tintelnot, J.; Schattling, B.; Winkler, H.; Bauer, S.; Kursawe, N.; Willing, A.; Keminer, O.; Ohana, O.; Salinas-Riester, G.; Pless, O.; Kuhl, D.; Friese, M.A. | Journal Article |
2016 | Aspirin prevents colorectal cancer metastasis in mice by splitting the crosstalk between platelets and tumor cells Guillem-Llobat, P.; Dovizio, M.; Bruno, A.; Ricciotti, E.; Cufino, V.; Sacco, A.; Grande, R.; Alberti, S.; Arena, V.; Cirillo, M.; Patrono, C.; FitzGerald, G.A.; Steinhilber, D.; Sgambato, A.; Patrignani, P. | Journal Article |
2016 | Assessing the suitability of the OECD 29 guidance document to investigate the transformation and dissolution of silver nanoparticles in aqueous media Wasmuth, Claus; Rüdel, Heinz; Düring, Rolf-Alexander; Klawonn, Thorsten | Journal Article |
2016 | Association analysis of psoriasis vulgaris and psoriatic arthritis with loss-of-function mutations in IL36RN in German patients Löhr, S.; Uebe, S.; Behrens, F.; Böhm, B.; Köhm, M.; Traupe, H.; Oji, V.; Burkhardt, H.; Reis, A.; Hüffmeier, U. | Journal Article |
2016 | Association of Improvement in Pain with Therapeutic Response as Determined by Individual Improvement Criteria in Patients with Rheumatoid Arthritis Scharbatke, E.C.; Behrens, F.; Schmalzing, M.; Koehm, M.; Greger, G.; Gnann, H.; Burkhardt, H.; Tony, H.-P. | Journal Article |
2016 | Attachment, growth, and detachment of human mesenchymal stem cells in a chemically defined medium Salzig, D.; Leber, J.; Merkewitz, K.; Lange, M.C.; Köster, N.; Czermak, P. | Journal Article |
2016 | Bacteria-host relationship: Ubiquitin ligases as weapons of invasion Maculins, T.; Fiskin, E.; Bhogaraju, S.; Dikic, I. | Journal Article |
2016 | Bacterial Expression and HTS Assessment of Soluble Epoxide Hydrolase Phosphatase Klingler, F.-M.; Wolf, M.; Wittmann, S.; Gribbon, P.; Proschak, E. | Journal Article |
2016 | Bioaccumulation of hexachlorobenzene in the terrestrial isopod Porcellio scaber Kampe, Sebastian; Schlechtriem, Christian | Journal Article |
2016 | Biomarkers and therapeutic targets for Alzheimer`s disease Perez-Cogram, Patricia; Altimiras, Francisco; Schuch, Wolfgang | Patent |
2016 | Biophysical and Functional Characterization of Rhesus Macaque IgG Subclasses Boesch, A.W.; Osei-Owusu, N.Y.; Crowly, A.R.; Chu, T.H.; Chan, Y.N.; Weiner, J.A.; Bharadwaj, P.; Hards, R.; Adamo, M.E.; Gerber, S.A.; Cocklin, S.L.; Schmitz, J.E.; Miles, A.R.; Eckman, J.W.; Belli, A.J.; Reimann, K.A.; Ackerman, M.E. | Journal Article |
2016 | Biota monitoring and the water framework directive - can normalization overcome shortcomings in sampling strategies? Fliedner, Annette; Rüdel, Heinz; Teubner, Diana; Buchmeier, Georgia; Lowis, Jaqueline; Heiss, Christiane; Wellmitz, Jörg; Koschorreck, Jan | Journal Article |
2016 | Boswellic acids immunomodulate T cell populations in relapsing-remitting multiple sclerosis in the SABA phase IIa clinical trial Stürner, K.H.; Stellmann, J.-P.; Dörr, J.-M.; Paul, F.; Keminer, O.; Vaas, L.; Pless, O.; Martin, R.; Heesen, C. | Abstract |
2016 | Brain lesion-pattern analysis in patients with olfactory dysfunctions following head trauma Lötsch, J.; Ultsch, A.; Eckhardt, M.; Huart, C.; Rombaux, P.; Hummel, T. | Journal Article |
2016 | Brain Mapping-Based Model of Δ9-Tetrahydrocannabinol Effects on Connectivity in the Pain Matrix Walter, C.; Oertel, B.G.; Felden, L.; Kell, C.A.; Nöth, U.; Vermehren, J.; Kaiser, J.; Deichmann, R.; Lötsch, J. | Journal Article |
2016 | Bridging across OECD 308 and 309 data in search of a robust biotransformation indicator Honti, Mark; Hahn, Stefan; Hennecke, Dieter; Junker, Thomas; Shrestha, Prasit; Fenner, Kathrin | Journal Article |
2016 | CD4+ T cells in patients with chronic inflammatory rheumatic disorders show distinct levels of exhaustion Frenz, T.; Grabski, E.; Buschjäger, D.; Vaas, L.A.I.; Burgdorf, N.; Schmidt, R.E.; Witte, T.; Kalinke, U. | Journal Article |
2016 | CD64-directed microtubule associated protein tau kills leukemic blasts ex vivo Mladenov, R.; Hristodorov, D.; Cremer, C.; Gresch, G.; Grieger, G.; Schenke, L.; Klose, D.; Amoury, M.; Woitok, M.; Jost, E.; Brümmerdorf, T.H.; Fendel, R.; Fischer, R.; Stein, C.; Thepen, T.; Barth, S. | Journal Article |
2016 | CD8+ Lymphocytes Are Required for Maintaining Viral Suppression in SIV-Infected Macaques Treated with Short-Term Antiretroviral Therapy Cartwright, E.K.; Spicer, L.; Smith, S.A.; Lee, D.; Fast, R.; Paganini, S.; Lawson, B.O.; Nega, M.; Easley, K.; Schmitz, J.E.; Bosinger, S.E.; Paiardini, M.; Chahroudi, A.; Vanderford, T.H.; Estes, J.D.; Lifson, J.D.; Derdeyn, C.A.; Silvestri, G. | Journal Article |
2016 | Cell biology: Ubiquitination without E1 and E2 enzymes Bhogaraju, S.; Dikic, I. | Journal Article |
2016 | Cellular analysis of the histamine H4 receptor in human myeloid cells Capelo, R.; Lehmann, C.; Ahmad, K.; Snodgrass, R.; Diehl, O.; Ringleb, J.; Flamand, N.; Weigert, A.; Stark, H.; Steinhilber, D.; Kahnt, A.S. | Journal Article |
2016 | Characterization and regulation of expression of an antifungal peptide from hemolymph of an insect, Manduca sexta Al Souhail, Q.; Hiromasa, Y.; Rahnamaeian, M.; Giraldo, M.C.; Takahashi, D.; Valent, B.; Vilcinskas, A.; Kanost, M.R. | Journal Article |
2016 | Characterization of a novel inhibitory human monoclonal antibody directed against Plasmodium falciparum Apical Membrane Antigen 1 Maskus, D.J.; Królik, M.; Bethke, S.; Spiegel, H.; Kapelski, S.; Seidel, M.; Addai-Mensah, O.; Reimann, A.; Klockenbring, T.; Barth, S.; Fischer, R.; Fendel, R. | Journal Article |
2016 | Characterization of Ra patients with a DAS28 response to adalimumab therapy by improvement in pain: A german nonintervention study Köhm, M.; Scharbatke, E.; Stemmler, E.; Greger, G.; Behrens, F.; Wittig, B. | Abstract |
2016 | Coevolution of parasitic fungi and insect hosts Joop, G.; Vilcinskas, A. | Journal Article |
2016 | Common Molecular Pathways in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Weishaupt, J.H.; Hyman, T.; Dikic, I. | Journal Article |
2016 | Comparative transcriptomics in three ladybird species supports a role for immunity in invasion biology Vogel, H.; Schmidtberg, H.; Vilcinskas, A. | Journal Article |
2016 | Comparison of etanercept monotherapy and combination therapy with methotrexate in psoriatic arthritis: Results from 2 clinical trials Combe, B.; Behrens, F.; McHugh, N.; Brock, F.; Kerkmann, U.; Kola, B.; Gallo, G. | Journal Article |
2016 | Comparison of tobacco host cell protein removal methods by blanching intact plants or by heat treatment of extracts Buyel, J.F.; Hubbuch, J.; Fischer, R. | Journal Article |
2016 | A computational functional genomics based self-limiting self-concentration mechanism of cell specialization as a biological role of jumping genes Lotsch, J.; Ultsch, A. | Journal Article |
2016 | Considerations of environmentally relevant test conditions for improved evaluation of ecological hazards of engineered nanomaterials Holden, Patricia A.; Gardea-Torresdey, Jorge L.; Klaessig, Fred; Turco, Ronald F.; Mortimer, Monika; Hund-Rinke, K.; Cohen Hubal, Elaine A.; Avery, David; Barceló, Damià; Behra, Renata; Cohen, Yoram; Deydier-Stephan, Laurence; Ferguson, P. Lee; Fernandes, Teresa F.; Herr Harthorn, Barbara; Henderson, W. Matthew; Hoke, Robert A.; Hristozov, Danail; Johnston, John M.; Kane, Agnes B.; Kapustka, Larry; Keller, Arturo A.; Lenihan, Hunter S.; Lovell, Wess; Murphy, Catherine J.; Nisbet, Roger M.; Petersen, Elijah J.; Salinas, Edward R.; Scheringer, Martin; Sharma, Monita; Speed, David E.; Sultan, Yasir; Westerhoff, Paul; White, Jason C.; Wiesner, Mark R.; Wong, Eva M.; Xing, Baoshan; Steele Horan, Meghan; Godwin, Hilary A.; Nel, André E. | Journal Article |
2016 | Controlled Release of Nor-β-lapachone by PLGA Microparticles: A Strategy for Improving Cytotoxicity against Prostate Cancer Cells Costa, M.P.; Feitosa, A.C.S.; Oliveira, F.C.E.; Cavalcanti, B.C.; Da Silva, E.N., Jr.; Dias, G.G.; Sales, F.A.M.; Sousa, B.L.; Barroso-Neto, I.L.; Pessoa, C.; Caetano, E.W.S.; Di Fiore, S.; Fischer, R.; Ladeira, L.O.; Freire, V.N. | Journal Article |
2016 | Cooperative interaction of antimicrobial peptides with the interrelated immune pathways in plants Moghaddam, M.R.B.; Vilcinskas, A.; Rahnamaeian, M. | Journal Article |
2016 | Corrigendum to "Linking the response of endocrine regulated genes to adverse effects on sex differentiation improves comprehension of aromatase inhibition in a Fish Sexual Development Test" Muth-Köhne, Elke; Westphal-Settele, Kathi; Brückner, Jasmin; Konradi, Sabine; Schiller, Viktoria; Baumann, Lisa; Schäfers, Christoph; Teigeler, Matthias; Fenske, Martina | Journal Article |
2016 | COX-2 gene dosage-dependent defects in kidney development Slattery, P.; Frölich, S.; Schreiber, Y.; Nüsing, R.M. | Journal Article |
2016 | CRISPR/Cas9 activity in the rice OsBEIIb gene does not induce off-target effects in the closely related paralog OsBEIIa Baysal, C.; Bortesi, L.; Zhu, C.; Farré, G.; Schillberg, S.; Christou, P. | Journal Article |
2016 | Critical micelle concentration values for different surfactants measured with solid-phase microextraction fibers Haftka, J.J.-H.; Scherpenisse, P.; Oetter, G.; Hodges, G.; Eadsforth, C.V.; Kotthoff, M.; Hermens, J.L.M. | Journal Article |
2016 | Cross-species extrapolation of uptake and disposition of neutral organic chemicals in fish using a multispecies physiologically-based toxicokinetic model framework Brinkmann, M.; Schlechtriem, C.; Reininghaus, M.; Eichbaum, K.; Buchinger, S.; Reifferscheid, G.; Hollert, H.; Preuss, T.G. | Journal Article |
2016 | Current levels and trends of selected EU Water Framework Directive priority substances in freshwater fish from the German environmental specimen bank Fliedner, Annette; Lohmann, Nina; Rüdel, Heinz; Teubner, Diana; Wellmitz, Jörg; Koschorreck, Jan | Journal Article |
2016 | CYP79D enzymes contribute to jasmonic acid-induced formation of aldoximes and other nitrogenous volatiles in two Erythroxylum species Luck, K.; Jirschitzka, J.; Irmisch, S.; Huber, M.; Gershenzon, J.; Köllner, T.G. | Journal Article |
2016 | A data science approach to candidate gene selection of pain regarded as a process of learning and neural plasticity Ultsch, A.; Kringel, D.; Kalso, E.; Mogil, J.S.; Lötsch, J. | Journal Article |
2016 | Dealing with nanosafety around the globe - Regulation vs. innovation Wacker, M.G.; Proykova, A.; Santos, G.M.L. | Journal Article |
2016 | Detection of psoriatic arthritis in patients with psoriasis in daily routine care using questionnaires for diagnosis of psoriatic arthritis and fluorescence-optical imaging technique Köhm, M.; Rossmanith, T.; Langer, H.E.; Burmester, G.; Wassenberg, S.; Kaesser, U.; Backhaus, M.; Burkhardt, H.; Behrens, F. | Abstract |
2016 | Detoxification and sensing mechanisms are of similar importance for Cd resistance in Caenorhabditis elegans Winter, Sarah A.; Dölling, Ramona; Knopf, Burkhard; Mendelski, Martha N.; Schäfers, Christoph; Paul, Rüdiger J. | Journal Article |
2016 | Development of a competitive cystatin C-specific bioassay suitable for repetitive measurements Damm, T.; Spiegel, H.; Barth, S.; Fischer, R.; Naehring, J. | Journal Article |
2016 | Development of a regulatory testing procedure to study the metabolism of pesticides in farmed fish Schlechtriem, Christian; Bischof, Ina; Atorf, Cornelia; Bergendahl, Elena; Seymour, Paul; Whalley, Paul | Journal Article |
2016 | Development of novel aminothiazole-comprising 5-LO inhibitors Kretschmer, S.B.M.; Woltersdorf, S.; Rödl, C.B.; Vogt, D.; Häfner, A.-K.; Steinhilber, D.; Stark, H.; Hofmann, B. | Journal Article |
2016 | Developments in the production of mucosal antibodies in plants Vasilev, Nikolay; Smales, C. Mark; Schillberg, Stefan; Fischer, Rainer; Schiermeyer, Andreas | Journal Article |
2016 | Diaryl Disulfides as Novel Stabilizers of Tumor Suppressor Pdcd4 Schmid, T.; Blees, J.S.; Bajer, M.M.; Wild, J.; Pescatori, L.; Crucitti, C.; Scipione, L.; Costi, R.; Henrich, C.J.; Brüne, B.; Colburn, N.H.; Santo, R. di | Journal Article |
2016 | Dietary burden calculations relating to fish metabolism studies Schlechtriem, Christian; Pucher, Johannes; Michalski, Britta | Journal Article |
2016 | Differences in toxicity of anionic and cationic PAMAM and PPI dendrimers in zebrafish embryos and cancer cell lines Bodewein, L.; Schmelter, F.; Di Fiore, S.; Hollert, H.; Fischer, R.; Fenske, M. | Journal Article |
2016 | Disagreement between two common biomarkers of global DNA methylation Knothe, C.; Shiratori, H.; Resch, E.; Ultsch, A.; Geisslinger, G.; Doehring, A.; Lötsch, J. | Journal Article |
2016 | Diversity, evolution and medical applications of insect antimicrobial peptides Mylonakis, E.; Podsiadlowski, L.; Muhammed, M.; Vilcinskas, A. | Journal Article |
2016 | Does concomitant methotrexate with adalimumab influence treatment outcomes in patients with psoriatic arthritis? Data from a large observational study Behrens, F.; Koehm, M.; Arndt, U.; Wittig, B.M.; Greger, G.; Thaci, D.; Scharbatke, E.; Tony, H.-P.; Burkhardt, H. | Journal Article |
2016 | Drug repurposing for the development of novel analgesics Sisignano, M.; Parnham, M.J.; Geisslinger, G. | Journal Article |
2016 | Ecological recovery potential of freshwater organisms: Consequences for environmental risk assessment of chemicals Gergs, Andre; Classen, Silke; Strauss, Tido; Ottermanns, Richard; Brock, Theo C.M.; Ratte, Hans Toni; Hommen, Udo; Preuss, Thomas G. | Book Article |
2016 | Effectiveness of Different Dosages of Retreatment of Rituximab in Combination with Leflunomide: Results from a Multicenter Randomized Placebo Controlled Investigator Initiated Clinical Trial in Active Rheumatoid Arthritis (Amara-Study Behrens, F.; Rossmanith, T.; Koehm, M.; Alten, R.; Aringer, M.; Burmester, G.R.; Feist, E.; Krüger, K.; Müller-Ladner, U.; Rubbert-Roth, A.; Wassenberg, S.; Tony, H.P.; Kellner, H.; Backhaus, M.; Burkhardt, H. | Abstract |
2016 | Effects of exercise on Irisin, BDNF and IL-6 serum levels in patients with progressive multiple sclerosis Briken, S.; Rosenkranz, S.C.; Keminer, O.; Patra, S.; Ketels, G.; Heesen, C.; Hellweg, R.; Pless, O.; Schulz, K.-H.; Gold, S.M. | Journal Article |
2016 | The efficient elimination of solid tumor cells by EGFR-specific and HER2-specific scFv-SNAP fusion proteins conjugated to benzylguanine-modified auristatin F Woitok, M.; Klose, D.; Niesen, J.; Richter, W.; Abbas, M.; Stein, C.; Fendel, R.; Bialon, M.; Püttmann, C.; Fischer, R.; Barth, S.; Kolberg, K. | Journal Article |
2016 | Electronic laboratory notebooks in a public-private partnership Vaas, L.A.I.; Witt, G.; Windshügel, B.; Bosin, A.; Serra, G.; Bruengger, A.; Winterhalter, M.; Gribbon, P.; Levy-Petelinkar, C.J.; Kohler, M. | Journal Article |
2016 | Elucidation of lipid metabolism pathways mediated by AMPK and nuclear receptors PPARδ and LXRα in human macrophages Kemmerer, M. | Dissertation |
2016 | Endocrine active environmental chemicals in foods Schäfers, C.; Licht, O.; Bitsch, A. | Journal Article |
2016 | Endokrin wirksame Umweltchemikalien in Lebensmitteln Schäfers, C.; Licht, O.; Bitsch, A. | Journal Article |
2016 | Endokrin wirksame Umweltchemikalien in Lebensmitteln Schäfers, C.; Licht, O.; Bitsch, A. | Journal Article |
2016 | Endokrin wirksame Umweltchemikalien in Lebensmitteln Schäfers, C.; Licht, O.; Bitsch, A. | Journal Article |
2016 | Endokrin wirksame Umweltchemikalien in Lebensmitteln Schäfers, C.; Licht, O.; Bitsch, A. | Journal Article |
2016 | Engineered human angiogenin mutations in the placental ribonuclease inhibitor complex for anticancer therapy Cong, X.; Cremer, C.; Nachreiner, T.; Barth, S.; Caloni, P. | Journal Article |
2016 | The enigma of ceramide synthase regulation in mammalian cells Wegner, M.-S.; Schiffmann, S.; Parnham, M.J.; Geisslinger, G.; Grösch, S. | Journal Article |
2016 | Enzymatic production of prebiotic fructo-oligosteviol glycosides Spohner, S.C.; Czermak, P. | Journal Article |
2016 | Epigenetic Control of Microsomal Prostaglandin E Synthase-1 by HDAC Mediated Recruitment of p300 Fork, C.; Vasconez, A.E.; Janetzko, P.; Angioni, C.; Schreiber, Y.; Ferreiros, N.; Geisslinger, G.; Leisegang, M.S.; Steinhilber, D.; Brandes, R.P. | Journal Article |
2016 | Erratum to: Making sense of big data in health research: Towards an EU action plan Auffray, C.; Balling, R.; Barroso, I.; Bencze, L.; Benson, M.; Bergeron, J.; Bernal-Delgado, E.; Blomberg, N.; Bock, C.; Conesa, A.; Signore, S. del; Delogne, C.; Devilee, P.; Meglio, A. di; Eijkemans, M.; Flicek, P.; Graf, N.; Grimm, V.; Guchelaar, H.J.; Guo, Y.K.; Gut, I.G.; Hanbury, A.; Hanif, S.; Hilgers, R.D.; Honrado, A.; Hose, D.R.; Houwing-Duistermaat, J.; Hubbard, T.; Janacek, S.H.; Karanikas, H.; Kievits, T.; Kohler, M.; Kremer, A.; Lanfear, J.; Lengauer, T.; Maes, E.; Meert, T.; Müller, W.; Nickel, D.; Oledzki, P.; Pedersen, B.; Petkovic, M.; Pliakos, K.; Rattray, M.; Mas, J.R.I.; Schneider, R.; Sengstag, T.; Serra-Picamal, X.; Spek, W.; Vaas, L.A.I.; Batenburg, O. van; Vandelaer, M.; Varnai, P.; Villoslada, P.; Vizcaíno, J.A.; Wubbe, J.P.M.; Zanetti, G. | Journal Article |
2016 | ESOM visualizations for quality assessment in clustering Ultsch, A.; Behnisch, M.; Lötsch, J. | Conference Paper |
2016 | Expanding the Ubiquitin Code Rajalingam, K.; Dikic, I. | Journal Article |
2016 | Expression and characterization of a recombinant i-type lysozyme from the harlequin ladybird beetle Harmonia axyridis Beckert, A.; Wiesner, J.; Schmidtberg, H.; Lehmann, R.; Baumann, A.; Vogel, H.; Vilcinskas, A. | Journal Article |
2016 | A fast and simple assay to quantify bacterial leukotoxin activity Oppermann, T.; Schwarz, S.; Busse, N.; Czermak, P. | Journal Article |
2016 | Features of CAM-cycling expressed in the dry season by terrestrial and epiphytic plants of Clusia arrudae Planchon & Triana in two rupestrian savannas of southeastern Brazil in comparison to the C3-species Eremanthus glomerulatus Less. Scarano, F.R.; Mattos, E.A. de; Franco, A.C.; Cavalin, P.O.; Orthen, B.; Fernandes, G.W.; Lüttge, U. | Journal Article |
2016 | Fluorescence-based ATG8 sensors monitor localization and function of LC3/GABARAP proteins Stolz, A.; Putyrski, M.; Kutle, I.; Huber, J.; Wang, C.; Major, V.; Sidhu, S.S.; Youle, R.J.; Rogov, V.V.; Dötsch, V.; Ernst, A.; Dikic, I. | Journal Article |
2016 | Food-Innovationen in Deutschland: Wahrnehmung und Wünsche von Verbrauchern Bücking, Mark; Hengse, Andreas | Journal Article |
2016 | Forizymes-functionalised artificial forisomes as a platform for the production and immobilisation of single enzymes and multi-enzyme complexes Visser, F.; Müller, B.; Rose, J.; Prüfer, D.; Noll, G.A. | Journal Article |
2016 | FR-900098, an antimalarial development candidate that inhibits the non-mevalonate isoprenoid biosynthesis pathway, shows no evidence of acute toxicity and genotoxicity Wiesner, Jochen; Ziemann, Christina; Hintz, Martin; Reichenberg, Armin; Ortmann, Regina; Schlitzer, Martin; Fuhst, Rainer; Timmesfeld, Nina; Vilcinskas, Andreas; Jomaa, Hassan | Journal Article |
2016 | Fraunhofer-Institut für Molekularbiologie und Angewandte Oekologie. Jahresbericht 2015 | Annual Report |
2016 | Fully human MAP-fusion protein selectively targets and eliminates proliferating CD64+ M1 macrophages Hristodorov, D.; Mladenov, R.; Fischer, R.; Barth, S.; Thepen, T. | Journal Article |
2016 | The functional interaction between abaecin and pore-forming peptides indicates a general mechanism of antibacterial potentiation Rahnamaeian, M.; Cytrynska, M.; Zdybicka-Barabas, A.; Vilcinskas, A. | Journal Article |
2016 | A generic platform for cellular screening against ubiquitin ligases Maculins, T.; Carter, N.; Dorval, T.; Hudson, K.; Nissink, J.W.M.; Hay, R.T.; Alwan, H. | Journal Article |
2016 | Genetically modified higher plants with increased photosynthesis and/or biomass production, methods and uses thereof Kreuzaler, Fritz; Nölke, Greta; Schillberg, Stefan; Barsoum, Mirna; Fischer, Rainer | Patent |
2016 | Genome editing: intellectual property and product development in plant biotechnology Schinkel, H.; Schillberg, S. | Journal Article |
2016 | Geruch und Ernährung. Tl.2: Die Charakteristik der Aromastoffe Kotthoff, Matthias; Nörenberg, Svenja | Journal Article |
2016 | Global Analysis of Host and Bacterial Ubiquitinome in Response to Salmonella Typhimurium Infection Fiskin, E.; Bionda, T.; Dikic, I.; Behrends, C. | Journal Article |
2016 | Granzyme B-based cytolytic fusion protein targeting EpCAM specifically kills triple negative breast cancer cells in vitro and inhibits tumor growth in a subcutaneous mouse tumor model Amoury, M.; Kolberg, K.; Pham, A.-T.; Hristodorov, D.; Mladenov, R.; Fiore, S. di; Helfrich, W.; Kiessling, F.; Fischer, R.; Pardo, A.; Thepen, T.; Hussain, A.F.; Nachreiner, T.; Barth, S. | Journal Article |
2016 | Guidance on the establishment of the residue definition for dietary risk assessment Adriaanse, Paulien; Brock, Theodorus; Berny, Philippe; Duquesne, Sabine; Grilli, Sandro; Hernandez-Jerez, Antonio F.; Hougaard Bennekou, Susanne; Klein, Michael; Kuhl, Thomas; Laskowski, Ryszard; Machera, Kyriaki; Ockleford, Colin; Ossendorp, Bernadette; Pelkonen, Olavi; Pieper, Silvia; Smith, Robert; Stemmer, Michael; Sundh, Ingvar; Teodorovic, Ivana; Aaldrik, Tiktak; Topping, Chris J.; Wolterink, Gerrit | Journal Article |
2016 | The H2S-producing enzyme CSE is dispensable for chronic pain signaling Syhr, K.M.J.; Boosen, M.; Hohmann, S.W.; Longen, S.; Köhler, Y.; Pfeilschifter, J.; Beck, K.F.; Geisslinger, G.; Schmidtko, A.; Kallenborn-Gerhardt, W. | Abstract |
2016 | Harmonization of environmental exposure assessment for veterinary pharmaceuticals and biocides: Influence of different experimental set-ups on observed mineralization. Herrchen, Monika; Hennecke, Dieter; Junker, Thomas; Düring, Rolf-Alexander; Thiele-Bruhn, Sören | Report |
2016 | Harmonization of environmental exposure assessment for veterinary pharmaceuticals and biocides: Literature review of studies on occurrence and transformation of veterinary pharmaceuticals and biocides in manure Düring, Rolf-Alexander; Wohde, Manuel; Junker, Thomas; Hennecke, Dieter; Herrchen, Monika; Thiele-Bruhn, Sören | Report |
2016 | Harmonization of environmental exposure assessment for veterinary pharmaceuticals and biocides: Ring test for validation of a draft test protocol for studies on transformation in manure Junker, Thomas; Römbke, Jörg; Hennecke, Dieter; Herrchen, Monika; Düring, Rolf-Alexander; Thiele-Bruhn, Sören; Meinerling, Maria; Fiebig, Silke; Topp, Ed; Völkel, Wolfgang | Report |
2016 | Hautmalignome und immunmodulierende Antirheumatikatherapie Burkhardt, H.; Weisenseel, P.; Radtke, M.A.; Krüger, K. | Journal Article |
2016 | Hepatocytes as in vitro test system to investigate metabolite patterns of pesticides in farmed rainbow trout and common carp: Comparison between in vivo and in vitro and across species Bischof, Ina; Köster, Jessica; Segner, Helmut; Schlechtriem, Christian | Journal Article |
2016 | Heterologous expression of Aspergillus terreus fructosyltransferase in Kluyveromyces lactis Spohner, S.C.; Czermak, P. | Journal Article |
2016 | Heterologous expression of cellulolytic enzymes Eckert, C.; Fischer, R.; Commandeur, U. | Book Article |
2016 | High-throughput analysis of global DNA methylation using methyl-sensitive digestion Shiratori, H.; Feinweber, C.; Knothe, C.; Lötsch, J.; Thomas, D.; Geisslinger, G.; Parnham, M.J.; Resch, E. | Journal Article |
2016 | High-yield production of a human monoclonal IgG by rhizosecretion in hydroponic tobacco cultures Madeira, L.M.; Szeto, T.H.; Henquet, M.; Raven, N.; Runions, J.; Huddleston, J.; Garrard, I.; Drake, P.M.W.; Ma, J.K.-C. | Journal Article |
2016 | The Histone Demethylase PHF8 Is Essential for Endothelial Cell Migration Gu, L.; Hitzel, J.; Moll, F.; Kruse, C.; Malik, R.A.; Preussner, J.; Looso, M.; Leisegang, M.S.; Steinhilber, D.; Brandes, R.P.; Fork, C. | Journal Article |
2016 | How many and which odor identification items are needed to establish normal olfactory function? Lötsch, J.; Ultsch, A.; Hummel, T. | Journal Article |
2016 | How the proteasome is degraded Hoeller, D.; Dikic, I. | Journal Article |
2016 | How TK-TD and population models for aquatic macrophytes could support the risk assessment for plant protection products Hommen, Udo; Schmitt, Walter; Heine, Simon; Brock, Theo C.M.; Duquesne, Sabine; Manson, Phil; Meregalli, Giovanna; Ochoa-Acuna, Hugo; Vliet, Peter van; Arts, Gertie | Journal Article |
2016 | How to fight against the decay - the burying beetle and its gut microbiota Heise, P.; Hirsch, R.; Vogel, H.; Vilcinskas, A. | Abstract |
2016 | How to use mechanistic effect models in environmental risk assessment of pesticides: Case studies and recommendations from the SETAC workshop MODELINK Hommen, Udo; Forbes, Valery; Grimm, Volker; Preuss, Thomas G.; Thorbek, Pernille; Ducrot, Verginie | Journal Article |
2016 | Identification and Characterization of a New Protein Isoform of Human 5-Lipoxygenase Häfner, A.-K.; Beilstein, K.; Graab, P.; Ball, A.-K.; Saul, M.J.; Hofmann, B.; Steinhilber, D. | Journal Article |
2016 | Identification of Small-Molecule Frequent Hitters of Glutathione S-Transferase-Glutathione Interaction Brenke, J.K.; Salmina, E.S.; Ringelstetter, L.; Dornauer, S.; Kuzikov, M.; Rothenaigner, I.; Schorpp, K.; Giehler, F.; Gopalakrishnan, J.; Kieser, A.; Gul, S.; Tetko, I.V.; Hadian, K. | Journal Article |
2016 | IgG binding characteristics of rhesus macaque FcgR Chan, Y.N.; Boesch, A.W.; Osei-Owusu, N.Y.; Emileh, A.; Crowley, A.R.; Cocklin, S.L.; Finstad, S.L.; Linde, C.H.; Howell, R.A.; Zentner, I.; Cocklin, S.; Miles, A.R.; Eckman, J.W.; Alter, G.; Schmitz, J.E.; Ackerman, M.E. | Journal Article |
2016 | IL-17 production by CSF lymphocytes as a biomarker for cerebral vasculitis Thom, V.; Schmid, S.; Gelderblom, M.; Hackbusch, R.; Kolster, M.; Schuster, S.; Thomalla, G.; Keminer, O.; Pleß, O.; Bernreuther, C.; Glatzel, M.; Wegscheider, K.; Gerloff, C.; Magnus, T.; Tolosa, E. | Journal Article |
2016 | Immuno-physiological adaptations confer wax moth Galleria mellonella resistance to Bacillus thuringiensis Dubovskiy, I.M.; Grizanova, E.V.; Whitten, M.M.A.; Mukherjee, K.; Greig, C.; Alikina, T.; Kabilov, M.; Vilcinskas, A.; Glupov, V.V.; Butt, T.M. | Journal Article |
2016 | The impact of endurance exercise on global and AMPK gene-specific DNA methylation King-Himmelreich, T.S.; Schramm, S.; Wolters, M.C.; Schmetzer, J.; Möser, C.V.; Knothe, C.; Resch, E.; Peil, J.; Geisslinger, G.; Niederberger, E. | Journal Article |
2016 | Improving the utilization of lignocellulosic biomass by polysaccharide modification Damm, T.; Commandeur, U.; Fischer, R.; Usadel, B.; Klose, H. | Journal Article |
2016 | Induction of experimental autoimmune encephalomyelitis in mice and evaluation of the disease-dependent distribution of immune cells in various tissues Barthelmes, J.; Tafferner, N.; Kurz, J.; de Bruin, N.; Parnham, M.J.; Geisslinger, G.; Schiffmann, S. | Journal Article |
2016 | Insect antimicrobial peptides: potential tools for the prevention of skin cancer Tonk, M.; Vilcinskas, A.; Rahnamaeian, M. | Journal Article |
2016 | An integrated metagenome and -proteome analysis of the microbial community residing in a biogas production plant Ortseifen, V.; Stolze, Y.; Maus, I.; Sczyrba, A.; Bremges, A.; Albaum, S.P.; Jaenicke, S.; Fracowiak, J.; Pühler, A.; Schlüter, A. | Journal Article |
2016 | Interferon-beta increases plasma ceramides of specific chain length in multiple sclerosis patients, unlike fingolimod or natalizumab Ottenlinger, F.M.; Mayer, C.A.; Ferreirós, N.; Schreiber, Y.; Schwiebs, A.; Schmidt, K.G.; Ackermann, H.; Pfeilschifter, J.M.; Radeke, H.H. | Journal Article |
2016 | Interleukin-38 is released from apoptotic cells to limit inflammatory macrophage responses Mora, J.; Schlemmer, A.; Wittig, I.; Richter, F.; Putyrski, M.; Frank, A.-C.; Han, Y.; Jung, M.; Ernst, A.; Weigert, A.; Brüne, B. | Journal Article |
2016 | A Jonah-like chymotrypsin from the therapeutic maggot Lucilia sericata plays a role in wound debridement and coagulation Pöppel, A.-K.; Kahl, M.; Baumann, A.; Wiesner, J.; Gökcen, A.; Beckert, A.; Preissner, K.T.; Vilcinskas, A.; Franta, Z. | Journal Article |
2016 | Kluyveromyces lactis as an expression host for enzymes that degrade lignocellulosic biomass Lambertz, C.; Eckert, C.; Fischer, R.; Commandeur, U. | Journal Article |
2016 | Kluyveromyces lactis: An emerging tool in biotechnology Spohner, S.C.; Schaum, V.; Quitmann, H.; Czermak, P. | Journal Article |
2016 | Lack of CerS2 Suppresses the Development of Experimental Autoimmune Encephalomyelitis by Impairing the Migratory Potential of Neutrophils Mayer, C.; Barthelmes, J.; Pewzner-Jung, Y.; Schmitz, K.; Maenner, A.; Foerch, C.; Eberle, M.; Taffemer, N.; Ferreiros, N.; Birod, K.; Geisslinger, G.; Futerman, A.; Grösch, S.; Schiffmann, S.; Schuhmann, C. | Abstract |
2016 | A latex metabolite benefits plant fitness under root herbivore attack Huber, M.; Epping, J.; Gronover, C.S.; Fricke, J.; Aziz, Z.; Brillatz, T.; Swyers, M.; Köllner, T.G.; Vogel, H.; Hammerbacher, A.; Triebwasser-Freese, D.; Robert, C.A.M.; Verhoeven, K.; Preite, V.; Gershenzon, J.; Erb, M. | Journal Article |
2016 | Lead removal from brass scrap by fluorine-free compound separation Hilgendorf, Simon; Binz, Florian; Welter, J.-M.; Friedrich, B. | Journal Article |
2016 | LEADS-PEP: A benchmark data set for assessment of peptide docking performance Hauser, A.S.; Windshügel, B. | Journal Article |
2016 | Die Lebensmittelindustrie muss innovativ sein Bücking, M.; Hengse, A. | Journal Article |
2016 | Linking the response of endocrine regulated genes to adverse effects on sex differentiation improves comprehension of aromatase inhibition in a Fish Sexual Development Test Muth-Köhne, Elke; Westphal-Settele, Kathi; Brückner, Jasmin; Konradi, Sabine; Schiller, Viktoria; Schäfers, Christoph; Teigeler, Matthias; Fenske, Martina | Journal Article |
2016 | Loss of HIF-1α in macrophages attenuates AhR/ARNT-mediated tumorigenesis in a PAH-driven tumor model Henke, N.; Ferreirós, N.; Geisslinger, G.; Ding, M.G.; Essler, S.; Fuhrmann, D.C.; Geis, T.; Namgaladze, D.; Dehne, N.; Brüne, B. | Journal Article |
2016 | A machine-learned computational functional genomics-based approach to drug classification Lötsch, J.; Ultsch, A. | Journal Article |
2016 | Machine-learned pattern identification in olfactory subtest results Lötsch, J.; Hummel, T.; Ultsch, A. | Journal Article |
2016 | Macrophage fatty acid oxidation and its roles in macrophage polarization and fatty acid-induced inflammation Namgaladze, D.; Brüne, B. | Journal Article |
2016 | Magnitude and quality of cytokine and chemokine storm during acute infection distinguish nonprogressive and progressive simian immunodeficiency virus infections of nonhuman primates Keating, S.M.; Heitman, J.W.; Wu, S.; Deng, X.; Stacey, A.R.; Zahn, R.C.; de la Rosa, M.; Finstad, S.L.; Lifson, J.D.; Piatak, M., Jr.; Gauduin, M.-C.; Kessler, B.M.; Ternette, N.; Carville, A.; Johnson, R.P.; Desrosiers, R.C.; Letvin, N.L.; Borrow, P.; Norris, P.J.; Schmitz, J.E. | Journal Article |
2016 | Making sense of big data in health research: Towards an EU action plan Auffray, C.; Balling, R.; Barroso, I.; Bencze, L.; Benson, M.; Bergeron, J.; Bernal-Delgado, E.; Blomberg, N.; Bock, C.; Conesa, A.; Signore, S. del; Delogne, C.; Devilee, P.; Meglio, A. di; Eijkemans, M.; Flicek, P.; Graf, N.; Grimm, V.; Guchelaar, H.-J.; Guo, Y.-K.; Gut, I.G.; Hanbury, A.; Hanif, S.; Hilgers, R.-D.; Honrado; Hose, D.R.; Houwing-Duistermaat, J.; Hubbard, T.; Janacek, S.H.; Karanikas, H.; Kievits, T.; Kohler, M.; Kremer, A.; Lanfear, J.; Lengauer, T.; Maes, E.; Meert, T.; Müller, W.; Nickel, D.; Oledzki, P.; Pedersen, B.; Petkovic, M.; Pliakos, K.; Rattray, M.; Redon i Màs, J.; Schneider, R.; Sengstag, T.; Serra-Picamal, X.; Spek, W.; Vaas, L.A.I.; Batenburg, O. van; Vandelaer, M.; Varnai, P.; Villoslada, P.; Vizcaíno, J.A.; Wubbe, J.P.M.; Zanetti, G. | Journal Article |
2016 | Manufacturing of human umbilical cord mesenchymal stromal cells on microcarriers in a dynamic system for clinical use Petry, F.; Smith, J.R.; Leber, J.; Salzig, D.; Czermak, P.; Weiss, M.L. | Journal Article |
2016 | Metabolic engineering of Clostridium cellulolyticum for the production of n-butanol from crystalline cellulose Gaida, S.M.; Liedtke, A.; Jentges, A.H.W.; Engels, B.; Jennewein, S. | Journal Article |
2016 | Metabolites from nematophagous fungi and nematicidal natural products from fungi as alternatives for biological control. Pt.II: Metabolites from nematophagous basidiomycetes and non-nematophagous fungi Degenkolb, T.; Vilcinskas, A. | Journal Article |
2016 | Metabolites from nematophagous fungi and nematicidal natural products from fungi as an alternative for biological control. Pt.I: Metabolites from nematophagous ascomycetes Degenkolb, T.; Vilcinskas, A. | Journal Article |
2016 | Methadone induces hypermethylation of human DNA Knothe, C.; Doehring, A.; Ultsch, A.; Lötsch, J. | Journal Article |
2016 | Method for providing stable isoindole derivatives Schramm, Oana Genoveva; Fiore, Stefano di; Fischer, Rainer | Patent |
2016 | Micro-optical prototyping of a surface acoustic wave-based point-of-care coagulation assay and first application in anticoagulated patients Moll, J.; Meyer dos Santos, S.; Hils, B.; Dornuf, F.; Rodrigues Meyer dos Santos, I.; Singer, O.C.; Ferreiros, N.; Labocha, S.; Blücher, A.; Harder, S.; Krozer, V. | Journal Article |
2016 | A microcosm study to support aquatic risk assessment of nickel: Community-level effects and comparison with bioavailability-normalized species sensitivity distributions Hommen, Udo; Knopf, Burkhard; Rüdel, Heinz; Schäfers, Christoph; Schamphelaere, Karel de; Schlekat, Chris; Rogevich Garman, Emily | Journal Article |
2016 | MicroRNAs in the Host Response to Viral Infections of Veterinary Importance Samir, M.; Vaas, L.A.I.; Pessler, F. | Journal Article |
2016 | Minimal Disease Activity Is a Stable Measure of Therapeutic Response in Psoriatic Arthritis Patients Receiving Treatment with Adalimumab Behrens, F.; Koehm, M.; Schwaneck, E.C.; Schmalzing, M.; Gnann, H.; Greger, G.; Tony, H.P.; Burkhardt, H. | Abstract |
2016 | The model beetle Tribolium castaneum can be used as an early warning system for transgenerational epigenetic side effects caused by pharmaceuticals Bingsohn, L.; Knorr, E.; Vilcinskas, A. | Journal Article |
2016 | Molecular farming Fischer, R.; Schillberg, S. | Book Article |
2016 | A Monoclonal Antibody That Discriminates between SNAP-Tagged and CLIP-Tagged Proteins Bialon, M.; Grezella, C.; Friesen, L.; Sieben, T.; Pham, A.-T.; Fischer, R.; Barth, S.; Püttmann, C.; Stein, C. | Journal Article |
2016 | Monotherapy with biologic disease-modifying anti-rheumatic drugs in rheumatoid arthritis Choy, E.; Aletaha, D.; Behrens, F.; Finckh, A.; Gomez-Reino, J.; Gottenberg, J.E.; Schuch, F.; Rubbert-Roth, A. | Journal Article |
2016 | More for less: Improving the biomass yield of a pear cell suspension culture by design of experiments Rasche, S.; Herwartz, D.; Schuster, F.; Jablonka, N.; Weber, A.; Fischer, R.; Schillberg, S. | Journal Article |
2016 | Multifaceted biological insights from a draft genome sequence of the tobacco hornworm moth, Manduca sexta Kanost, M.R.; Arrese, E.L.; Cao, X.; Chen, Y.-R.; Chellapilla, S.; Goldsmith, M.R.; Grosse-Wilde, E.; Heckel, D.G.; Herndon, N.; Jiang, H.; Papanicolaou, A.; Qu, J.; Soulages, J.L.; Vogel, H.; Walters, J.; Waterhouse, R.M.; Ahn, S.-J.; Almeida, F.C.; An, C.; Aqrawi, P.; Bretschneider, A.; Bryant, W.B.; Bucks, S.; Chao, H.; Chevignon, G.; Christen, J.M.; Clarke, D.F.; Dittmer, N.T.; Ferguson, L.C.F.; Garavelou, S.; Gordon, K.H.J.; Gunaratna, R.T.; Han, Y.; Hauser, F.; He, Y.; Heidel-Fischer, H.; Hirsh, A.; Hu, Y.; Jiang, H.; Kalra, D.; Klinner, C.; König, C.; Kovar, C.; Kroll, A.R.; Kuwar, S.S.; Lee, S.L.; Lehman, R.; Li, K.; Li, Z.; Liang, H.; Lovelace, S.; Lu, Z.; Mansfield, J.H.; McCulloch, K.J.; Mathew, T.; Morton, B.; Muzny, D.M.; Neunemann, D.; Ongeri, F.; Pauchet, Y.; Pu, L.-L.; Pyrousis, I.; Rao, X.-J.; Redding, A.; Roesel, C.; Sanchez-Gracia, A.; Schaack, S.; Shukla, A.; Tetreau, G.; Wang, Y.; Xiong, G.-H.; Traut, W.; Walsh, T.K.; Worley, K.C.; Wu, D.; Wu, W.; Wu, Y.-Q.; Zhang, X.; Zou, Z.; | Journal Article |
2016 | Multiphase mixing characteristics in a microcarrier-based stirred tank bioreactor suitable for human mesenchymal stem cell expansion Grein, T.A.; Leber, J.; Blumenstock, M.; Petry, F.; Weidner, T.; Salzig, D.; Czermak, P. | Journal Article |
2016 | Multiple rodent models and behavioral measures reveal unexpected responses to FTY720 and DMF in experimental autoimmune encephalomyelitis Bruin, N.M.W.J. de; Schmitz, K.; Schiffrnann, S.; Tafferner, N.; Schmidt, M.; Jordan, H.; Häußler, A.; Tegeder, I.; Geisslinger, G.; Parnham, M.J. | Journal Article |
2016 | N-Benzylbenzamides: A novel merged scaffold for orally available dual soluble epoxide hydrolase/peroxisome proliferator-activated receptor gamma modulators Blöcher, R.; Lamers, C.; Wittmann, S.K.; Merk, D.; Hartmann, M.; Weizel, L.; Diehl, O.; Brüggerhoff, A.; Boss, M.; Kaiser, A.; Schader, T.; Gobel, T.; Grundmann, M.; Angioni, C.; Heering, J.; Geisslinger, G.; Wurglics, M.; Kostenis, E.; Brüne, B.; Steinhilber, D.; Schubert-Zsilavecz, M.; Kahnt, A.S.; Proschak, E. | Journal Article |
2016 | N-terminally truncated interleukin-38 Weigert, Andreas; Mora, Javier; Brüne, Bernhard; Dillmann, Christina; Parnham, Michael John | Patent |
2016 | A new family of N-terminally truncated peptaibols from the biocontrol fungus trichoderma harzianum Degenkolb, T.; Röhrich, C.R.; Vilcinscas, A.; Döhren, H. von; Brückner, H. | Abstract |
2016 | Next generation sequencing identifies five major classes of potentially therapeutic enzymes secreted by Lucilia sericata medical maggots Franta, Z.; Vogel, H.; Lehmann, R.; Rupp, O.; Goesmann, A.; Vilcinskas, A. | Journal Article |
2016 | Next-generation sequencing of amplicons is a rapid and reliable method for the detection of polymorphisms relevant for barley breeding Fritsch, L.; Soeur, R.; Hansen, C.; Fischer, R.; Schillberg, S.; Schröper, F. | Journal Article |
2016 | Next-generation sequencing of human opioid receptor genes based on a custom AmpliSeq™ library and ion torrent personal genome machine Kringel, D.; Lötsch, J. | Journal Article |
2016 | A novel approach for targeted elimination of CSPG4-positive triple-negative breast cancer cells using a MAP tau-based fusion protein Amoury, M.; Mladenov, R.; Nachreiner, T.; Pham, A.-T.; Hristodorov, D.; Di Fiore, S.; Helfrich, W.; Pardo, A.; Fey, G.; Schwenkert, M.; Thepen, T.; Kiessling, F.; Hussain, A.F.; Fischer, R.; Kolberg, K.; Barth, S. | Journal Article |
2016 | A novel fully-human cytolytic fusion protein based on granzyme B shows in vitro cytotoxicity and ex vivo binding to solid tumors overexpressing the epidermal growth factor receptor Niesen, J.; Hehmann-Titt, G.; Woitok, M.; Fendel, R.; Barth, S.; Fischer, R.; Stein, C. | Journal Article |
2016 | Novel fusion proteins for the antigen-specific staining and elimination of B cell receptor-positive cell populations demonstrated by a tetanus toxoid fragment C (TTC) model antigen Klose, D.; Saunders, U.; Barth, S.; Fischer, R.; Jacobi, A.M.; Nachreiner, T. | Journal Article |
2016 | Novel polymeric micelles for drug delivery: Material characterization and formulation screening Janas, C.; Mostaphaoui, Z.; Schmiederer, L.; Bauer, J.; Wacker, M.G. | Journal Article |
2016 | Nucampholin nucleic acid molecules to control coleopteran insect pests Vilcinskas, Andreas; Knorr, Eileen; Narva, Kenneth E.; Gandra, Premchand; Worden, Sarah E. | Patent |
2016 | Numeric simulation can be used to predict heat transfer during the blanching of leaves and intact plants Buyel, J.F. | Journal Article |
2016 | Optimization of N'-(arylsulfonyl)pyrazoline-1-carboxamidines by exploiting a novel interaction site in the 5-HT6 antagonistic binding pocket Loevezijn, A. van; Venhorst, J.; Iwema Bakker, W.I.; Lange, J.H.M.; Looff, W. de; Henzen, R.; Vries, J. de; Woestijne, R.P. van de; Hartog, A.P. den; Verhoog, S.; Neut, M.A.W. van der; Bruin, N.M.W.J. de; Kruse, C.G. | Journal Article |
2016 | Optimization of plant cell suspension cultures for the production of recombinant proteins Santos, R.B.; Schiermeyer, A.; Abranches, R. | Abstract |
2016 | Optimized blanching reduces the host cell protein content and substantially enhances the recovery and stability of two plant-derived malaria vaccine candidates Menzel, S.; Holland, T.; Boes, A.; Spiegel, H.; Bolzenius, J.; Fischer, R.; Buyel, J.F. | Journal Article |
2016 | Optimizing novel implant formulations for the prolonged release of biopharmaceuticals using in vitro and in vivo imaging techniques Beyer, S.; Xie, L.; Schmidt, M.; De Bruin, N.; Ashtikar, M.; Rüschenbaum, S.; Lange, C.M.; Vogel, V.; Mäntele, W.; Parnham, M.J.; Wacker, M.G. | Journal Article |
2016 | Optimizing the design of a reproduction toxicity test with the pond snail Lymnaea stagnalis Charles, Sandrine; Ducrot, Virginie; Azam, Didier; Benstead, Rachel; Brettschneider, Denise; Schamphelaere, Karel de; Goncalves, Sandra Filipe; Green, John W.; Holbech, Henrik; Hutchinson, Thomas H.; Faber, Daniel; Laranjeiro, Filipe; Matthiessen, Peter; Norrgren, Leif; Oehlmann, Jörg; Reategui-Zirena, Evelyn; Seeland-Fremer, Anne; Teigeler, Matthias; Thome, Jean-Pierre; Tobor Kaplon, Marysia; Weltje, Lennart; Lagadic, Laurent | Journal Article |
2016 | Overcoming low yields of plant-made antibodies by a protein engineering approach Zischewski, J.; Sack, M.; Fischer, R. | Journal Article |
2016 | PAFAH1B1 and the lncRNA NONHSAT073641 maintain an angiogenic phenotype in human endothelial cells Josipovic, I.; Fork, C.; Preussner, J.; Prior, K.-K.; Iloska, D.; Vasconez, A.E.; Labocha, S.; Angioni, C.; Thomas, D.; Ferreirós, N.; Looso, M.; Pullamsetti, S.S.; Geisslinger, G.; Steinhilber, D.; Brandes, R.P.; Leisegang, M.S. | Journal Article |
2016 | Patterns of CRISPR/Cas9 activity in plants, animals and microbes Bortesi, L.; Zhu, C.; Zischewski, J.; Perez, L.; Bassié, L.; Nadi, R.; Forni, G.; Lade, S.B.; Soto, E.; Jin, X.; Medina, V.; Villorbina, G.; Munoz, P.; Farré, G.; Fischer, R.; Twyman, R.M.; Capell, T.; Christou, P.; Schillberg, S. | Journal Article |
2016 | Pesticide exposure assessment for surface waters in the EU. Pt.1: Some comments on the current procedure Bach, Martin; Diesner, Mirjam; Großmann, Dietlinde; Guerniche, Djamal; Hommen, Udo; Klein, Michael; Kubiak, Roland; Müller, Alexandra; Priegnitz, Jan; Reichenberger, Stefan; Thomas, Kai; Trapp, Matthias | Journal Article |
2016 | Pharmacoepigenetics of the role of DNA methylation in μ-opioid receptor expression in different human brain regions Knothe, C.; Oertel, B.G.; Ultsch, A.; Kettner, M.; Schmidt, P.H.; Wunder, C.; Toennes, S.W.; Geisslinger, G.; Lötsch, J. | Journal Article |
2016 | Pharmacokinetic Analysis of Mycophenolate Mofetil and Enteric-Coated Mycophenolate Sodium in Calcineurin Inhibitor Graff, J.; Scheuermann, E.-H.; Brandhorst, G.; Oellerich, M.; Gossmann, J. | Journal Article |
2016 | Phosphoribosylation of Ubiquitin Promotes Serine Ubiquitination and Impairs Conventional Ubiquitination Bhogaraju, S.; Kalayil, S.; Liu, Y.; Bonn, F.; Colby, T.; Matic, I.; Dikic, I. | Journal Article |
2016 | Photocatalytic pavements with epoxy-bonded TiO2-containing spreading material Wang, D.; Leng, Z.; Hüben, M.; Oeser, M.; Steinauer, B. | Journal Article |
2016 | Photoimmunotheranostic agents for triple-negative breast cancer diagnosis and therapy that can be activated on demand Amoury, M.; Bauerschlag, D.; Zeppernick, F.; Felbert, V.; Berges, N.; Fiore, S.D.; Mintert, I.; Bleilevens, A.; Maass, N.; Bräutigam, K.; Meinhold-Heerlein, I.; Stickeler, E.; Barth, S.; Fischer, R.; Hussain, A.F. | Journal Article |
2016 | Phototheranostics immunoconjugates to detect eliminate triple negative breast cancer cells Hussain, A.; Zeppernick, E.; Amoury, M.; Bauerschlag, D.O.; Maass, N.; Bräutigam, K.; Meinhold-Heerlein, I.; Fischer, R.; Barth, S. | Abstract |
2016 | Plant Cell-Based Recombinant Antibody Manufacturing with a 200 L Orbitally Shaken Disposable Bioreactor Raven, N.; Schillberg, S.; Rasche, S. | Book Article |
2016 | A Plant-Based Transient Expression System for the Rapid Production of Malaria Vaccine Candidates Boes, A.; Reimann, A.; Twyman, R.M.; Fischer, R.; Schillberg, S.; Spiegel, H. | Book Article |
2016 | The Plasmodium falciparum blood stages acquire factor H family proteins to evade destruction by human complement Rosa, T.F.A.; Flammersfeld, A.; Ngwa, C.J.; Kiesow, M.; Fischer, R.; Zipfel, P.F.; Skerka, C.; Pradel, G. | Journal Article |
2016 | Polyclonal antibodies for specific detection of tobacco host cell proteins can be efficiently generated following RuBisCO depletion and the removal of endotoxins Arfi, Z.A.; Hellwig, S.; Drossard, J.; Fischer, R.; Buyel, J.F. | Journal Article |
2016 | The potential of the Galleria mellonella innate immune system is maximized by the co-presentation of diverse antimicrobial peptides Bolouri Moghaddam, M.R.; Tonk, M.; Schreiber, C.; Salzig, D.; Czermak, P.; Vilcinskas, A.; Rahnamaeian, M. | Journal Article |
2016 | Pparγ Expression in T Cells as a Prognostic Marker of Sepsis Brenneis, M.; Aghajaanpour, R.; Knape, T.; Sha, L.K.; Neb, H.; Meybohm, P.; Zacharowski, K.; Hauser, I.A.; Buttner, S.; Parnham, M.J.; Brune, B.; Knethen, A. von | Journal Article |
2016 | The Predict Study: low risk for digital ulcer development in patients with systemic sclerosis with increasing disease duration and lack of topoisomerase-1 antibodies Hunzelmann, N.; Riemekasten, G.; Becker, M.O.; Moinzadeh, P.; Kreuter, A.; Melchers, I.; Mueller-Ladner, U.; Meier, F.; Worm, M.; Lee, H.; Herrgott, I.; Pfeiffer, C.; Fierlbeck, G.; Henes, J.; Juche, A.; Zeidler, G.; Mensing, H.; Günther, C.; Sárdy, M.; Burkhardt, H.; Koehm, M.; Kuhr, K.; Krieg, T.; Sunderkötter, C. | Journal Article |
2016 | Predictive Value of Different Tools for Detection of Psoriatic Arthritis in Patients with Psoriasis in Daily Routine Care Using Questionnaires for Diagnosis of Psoriatic Arthritis and Fluorescence-Optical Imaging Technique Koehm, M.; Rossmanith, T.; Langer, H.E.; Burmester, G.R.; Wassenberg, S.; Köhler, B.; Kaesser, U.; Backhaus, M.; Burkhardt, H.; Behrens, F. | Abstract |
2016 | Pro-inflammatory obesity in aged cannabinoid-2 receptor-deficient mice Schmitz, K.; Mangels, N.; Häussler, A.; Ferreiros, N.; Fleming, I.; Tegeder, I. | Journal Article |
2016 | Procedure to evaluate the efficiency of flocculants for the removal of dispersed particles from plant extracts Buyel, J.F. | Journal Article |
2016 | Process Pharmacology: A Pharmacological Data Science Approach to Drug Development and Therapy Lötsch, J.; Ultsch, A. | Journal Article |
2016 | Production and purification of virus particles for the use in cancer therapy Grein, T.A.; Weidner, T.; Mühlebach, T.; Salzig, M.D.; Czermak, D. | Abstract |
2016 | Production of Human papillomavirus pseudovirions in plants and their use in pseudovirion-based neutralisation assays in mammalian cells Lamprecht, R.L.; Kennedy, P.; Huddy, S.M.; Bethke, S.; Hendrikse, M.; Hitzeroth, I.I.; Rybicki, E.P. | Journal Article |
2016 | Production of immunoabsorbent nanoparticles by displaying single-domain protein A on potato virus X Uhde-Holzem, K.; McBurney, M.; Tiu, B.D.B.; Advincula, R.C.; Fischer, R.; Commandeur, U.; Steinmetz, N.F. | Journal Article |
2016 | Production, quality control, stability and pharmacotoxicity of a malaria vaccine comprising three highly similar PfAMA1 protein molecules to overcome antigenic variation Faber, B.W.; Hellwig, S.; Houard, S.; Havelange, N.; Drossard, J.; Mertens, H.; Croon, A.; Kastilan, R.; Byrne, R.; Werff, N. van der; Eijk, M. van der; Thomas, A.W.; Kocken, C.H.M.; Remarque, E.J. | Journal Article |
2016 | Profiling of flavonol derivatives for the development of antitrypanosomatidic drugs Borsari, C.; Lucian, R.; Pozz, C.; Poehner, I.; Henrich, S.; Trande, M.; Cordeiro-Da-silva, A.; Santarem, N.; Baptista, C.; Tait, A.; Di Pisa, F.; Iacono, L.D.; Landi, G.; Gul, S.; Wolf, M.; Kuzikov, M.; Ellinger, B.; Reinshagen, J.; Witt, G.; Gribbon, P.; Kohler, M.; Keminer, O.; Behrens, B.; Costantino, L.; Nevado, P.T.; Bifeld, E.; Eick, J.; Clos, J.; Torrado, J.; Jiménez-Antón, M.D.; Corral, M.J.; Alunda, J.Ma.; Pellati, F.; Wade, R.C.; Ferrari, S.; Mangani, S.; Costi, M.P. | Journal Article |
2016 | Progress and obstacles in the production and application of recombinant lignin-degrading peroxidases Lambertz, C.; Ece, S.; Fischer, R.; Commandeur, U. | Journal Article |
2016 | Prophylaxis of hereditary angioedema attacks Aygören-Pürsün, E.; Magerl, M.; Graff, J.; Martinez-Saguer, I.; Kreuz, W.; Longhurst, H.; Nasr, I.; Bas, M.; Straßen, U.; Fang, L.; Cornpropst, M.; Dobo, S.; Collis, P.; Sheridan, W.P.; Maurer, M. | Journal Article |
2016 | The protein kinase IKKepsilon contributes to tumour growth and tumour pain in a melanoma model Möser, C.V.; Meissner, M.; Laarmann, K.; Olbrich, K.; King-Himmelreich, T.S.; Wolters, M.C.; Geisslinger, G.; Niederberger, E. | Journal Article |
2016 | Psoriasisarthritis: Übersicht medikamentöser Therapieoptionen und Anwendungsbesonderheiten Behrens, F.; Thaci, D.; Wollenhaupt, J.; Krüger, K. | Journal Article |
2016 | Psoriatic arthritis Koehm, M.; Behrens, F. | Book Article |
2016 | Purification and characterization of the plant produced human surfactant protein D (hSP–D) Salgado, Bustos, D.A. | Dissertation |
2016 | Purification and immunogenicity of hemagglutinin from highly pathogenic avian influenza virus H5N1 expressed in Nicotiana benthamiana Pua, T.-L.; Chan, X.Y.; Loh, H.-S.; Omar, A.R.; Yusibov, V.; Musiychuk, K.; Hall, A.L.; Coffin, M.V.; Shoji, Y.; Chichester, J.A.; Bi, H.; Streatfield, S.J. | Journal Article |
2016 | Putting the spotlight back on plant suspension cultures Santos, R.B.; Abranches, R.; Fischer, R.; Sack, M.; Holland, T. | Journal Article |
2016 | Regulation of tumorigenic Wnt signaling by cyclooxygenase-2, 5-lipoxygenase and their pharmacological inhibitors Roos, J.; Grösch, S.; Werz, O.; Schröder, P.; Ziegler, S.; Fulda, S.; Paulus, P.; Urbschat, A.; Kühn, B.; Maucher, I.; Fettel, J.; Vorup-Jensen, T.; Piesche, M.; Matrone, C.; Steinhilber, D.; Parnham, M.J.; Maier, T.J. | Journal Article |
2016 | Regulatory ecotoxicity testing of nanomaterials - proposed modifications of OECD test guidelines based on laboratory experience with silver and titanium dioxide nanoparticles Hund-Rinke, Kerstin; Baun, Anders; Cupi, Denisa; Fernandes, Teresa F.; Handy, Richard; Kinross, John H.; Navas, Jose Maria; Peijnenburg, Willie J.G.M.; Schlich, Karsten; Shaw, Benjamin J.; Scott-Fordsmand, Janeck | Journal Article |
2016 | Reintroducing environmental change drivers in biodiversity-ecosystem functioning research Laender, Frederik de; Rohr, Jason R.; Ashauer, Roman; Baird, Donald J.; Berger, Uta; Eisenhauer, Nico; Grimm, Volker; Hommen, Udo; Maltby, Lorraine; Meliàn, Carlos J.; Pomati, Francesco; Roessink, Ivo; Radchuk, Viktoriia; Brink, Paul J. van den | Journal Article |
2016 | Replication of a distinct psoriatic arthritis risk variant at IL23R Budu-Aggrey, A.; Bowes, J.; Lohr, S.; Uebe, S.; Zervou, M.I.; Helliwell, P.; Ryan, A.W.; Kane, D.; Korendowych, E.; Giardina, E.; Packham, J.; McManus, R.; FitzGerald, O.; McHugh, N.; Behrens, F.; Burkhardt, H.; Huffmeier, U.; Ho, P.; Martin, J.; Castaneda, S.; Goulielmos, G.; Reis, A.; Barton, A. | Abstract |
2016 | Replication of a distinct psoriatic arthritis risk variant at the IL23R locus Budu-Aggrey, A.; Bowes, J.; Loehr, S.; Uebe, S.; Zervou, M.I.; Helliwell, P.; Ryan, A.W.; Kane, D.; Korendowych, E.; Giardina, E.; Packham, J.; McManus, R.; Fitzgerald, O.; McHugh, N.; Behrens, F.; Burkhardt, H.; Huffmeier, U.; Ho, P.; Martin, J.; Castaneda, S.; Goulielmos, G.; Reis, A.; Barton, A. | Journal Article |
2016 | Results of extended plant tests using more realistic exposure scenarios for improving environmental risk assessment of veterinary pharmaceuticals Richter, Elisabeth; Berkner, Silvia; Ebert, Ina; Förster, Bernhard; Graf, Nadin; Herrchen, Monika; Kuehnen, Ute; Römbke, Jörg; Simon, Markus | Journal Article |
2016 | Risk mitigation in academic drug discovery Ellinger, B.; Gribbon, P. | Journal Article |
2016 | Rituximab in combination with leflunomide: Results from a multicenter randomized placebo controlled investigator initiated clinical trial in active rheumatoid arthritis (Amara-Study) Behrens, F.; Rossmanith, T.; Köhm, M.; Alten, R.; Aringer, M.; Backhaus, M.; Baerwald, C.; Burmester, G.; Feist, E.; Kellner, H.; Krüger, K.; Müller-Ladner, U.; Rubbert-Roth, A.; Tony, H.P.; Wassenberg, S.; Burkhardt, H. | Abstract |
2016 | The role of epigenetics in host-parasite coevolution: Lessons from the model host insects Galleria mellonella and Tribolium castaneum Vilcinskas, A. | Journal Article |
2016 | Screening for potential endocrine disruptors - evidence from structural alerts, in vitro and in vivo toxicological assays Nendza, M.; Wenzel, A.; Müller, M. | Abstract |
2016 | Screening for potential endocrine disruptors in fish: Evidence from structural alerts and in vitro and in vivo toxicological assays Nendza, Monika; Wenzel, Andrea; Müller, Martin; Lewin, Geertje; Simetska, Nelly; Stock, Frauke; Arning, Jürgen | Journal Article |
2016 | The selective 5-HT6 receptor antagonist SLV has putative cognitive- and social interaction enhancing properties in rodent models of cognitive impairment Bruin, N.M.W.J. de; Loevezijn, A. van; Wicke, K.M.; Haan, M. de; Venhorst, J.; Lange, J.H.M.; Groote, L. de; Neut, M.A.W. van der; Prickaerts, J.; Andriambeloson, E.; Foley, A.G.; Drimmelen, M. van; Wetering, M. van der; Kruse, C.G. | Journal Article |
2016 | Sequences of stilboflavin C: towards the peptaibiome of the filamentous fungus Stilbella (= Trichoderma) flavipes Degenkolb, T.; Götze, L.; Döhren, H. von; Vilcinskas, A.; Brückner, H. | Journal Article |
2016 | Severe obesity is frequent in patients with psoriatic arthritis and is accompanied by increased cardiovascular risk Huscher, D.; Albrecht, K.; Bischoff, S.; Thiele, K.; Behrens, F.; Hoese, G.; Ochs, W.; Zink, A. | Abstract |
2016 | SF3: Unusual Antimicrobial Hexapeptides from a Streptomyces sp Strain Dardic, D.; Hirsch, R.; Druzineck, D.; Wiesner, J.; Bauer, A.; Vilcinskas, A.; Hammann, P.; Plaza, A. | Abstract |
2016 | Silver and gold nanoparticle separation using asymmetrical flow-field flow fractionation: Influence of run conditions and of particle and membrane charges Meisterjahn, Boris; Wagner, Stephan; Kammer, Frank von der; Hennecke, Dieter; Hofmann, Thilo | Journal Article |
2016 | Simulation studies to explore biodegradation in water-sediment systems: From OECD 308 to OECD 309 Shrestha, Prasit; Junker, Thomas; Fenner, Kathrin; Hahn, Stefan; Honti, Mark; Bakkour, Rani; Diaz, Cecilia; Hennecke, Dieter | Journal Article |
2016 | Single versus repeated applications of CuO and Ag nanomaterials and their effect on soil microflora Schlich, Karsten; Beule, Lukas; Hund-Rinke, Kerstin | Journal Article |
2016 | Single-Step RNA Extraction from Different Hydrogel-Embedded Mesenchymal Stem Cells for Quantitative Reverse Transcription-Polymerase Chain Reaction Analysis Köster, N.; Schmiermund, A.; Grubelnig, S.; Leber, J.; Ehlicke, F.; Czermak, P.; Salzig, D. | Journal Article |
2016 | A small yet comprehensive subset of human experimental pain models emerging from correlation analysis with a clinical quantitative sensory testing protocol in healthy subjects Lötsch, J.; Dimova, V.; Ultsch, A.; Lieb, I.; Zimmermann, M.; Geisslinger, G.; Oertel, B.G. | Journal Article |
2016 | Smell of pain: Intersection of nociception and olfaction Lötsch, J.; Hähner, A.; Gossrau, G.; Hummel, C.; Walter, C.; Ultsch, A.; Hummel, T. | Journal Article |
2016 | SNAP-Tag Technology: A Useful Tool to Determine Affinity Constants and Other Functional Parameters of Novel Antibody Fragments Niesen, J.; Sack, M.; Seidel, M.; Fendel, R.; Barth, S.; Fischer, R.; Stein, C. | Journal Article |
2016 | Sorption of Highly Hydrophobic Organic Chemicals to Organic Matter Relevant for Fish Bioconcentration Studies Böhm, L.; Schlechtriem, C.; Düring, R.-A. | Journal Article |
2016 | Specific photoimmuno-theranostics for detection and elimination of skin cancer cells Barth, Stefan; Fischer, Rainer; Hussain, Ahmad | Patent |
2016 | A specific photoimmunotheranostics agent to detect and eliminate skin cancer cells expressing EGFR Felbert, V. von; Bauerschlag, D.; Maass, N.; Bräutigam, K.; Meinhold-Heerlein, I.; Woitok, M.; Barth, S.; Hussain, A.F. | Journal Article |
2016 | Statistical experimental designs for the production of secondary metabolites in plant cell suspension cultures Schmitz, C.; Fritsch, L.; Fischer, R.; Schillberg, S.; Rasche, S. | Journal Article |
2016 | Structure of ThiM from Vitamin B1 biosynthetic pathway of Staphylococcus aureus - Insights into a novel pro-drug approach addressing MRSA infections Drebes, J.; Künz, M.; Windshügel, B.; Kikhney, A.G.; Müller, I.B.; Eberle, R.J.; Oberthür, D.; Cang, H.; Svergun, D.I.; Perbandt, M.; Betzel, C.; Wrenger, C. | Journal Article |
2016 | Structured plant metabolomics for the simultaneous exploration of multiple factors Vasilev, N.; Boccard, J.; Lang, G.; Grömping, U.; Fischer, R.; Goepfert, S.; Rudaz, S.; Schillberg, S. | Journal Article |
2016 | Tackling unwanted proteolysis in plant production hosts used for molecular farming Mandal, Manoj K.; Ahvari, Houtan; Schillberg, Stefan; Schiermeyer, Andreas | Journal Article |
2016 | Targeted gene exchange in plant cells mediated by a zinc finger nuclease double cut Schneider, Katja; Schiermeyer, Andreas; Dolls, Anja; Koch, Natalie; Herwartz, Denise; Kirchhoff, Janina; Fischer, Rainer; Russell, Sean M.; Cao, Zehui; Corbin, David R.; Sastry-Dent, Lakshmi; Ainley, W. Michael; Webb, Steven R.; Schinkel, Helga; Schillberg, Stefan | Journal Article |
2016 | Targeting c-kit receptor in neuroblastomas and colorectal cancers using stem cell factor (SCF)-based recombinant bacterial toxins Choudhary, S.; Pardo, A.; Rosinke, R.; Batra, J.K.; Barth, S.; Verma, R.S. | Journal Article |
2016 | Targeting CYP2J to reduce paclitaxel-induced peripheral neuropathic pain Sisignano, M.; Angioni, C.; Park, C.-K.; Santos, S.M.D.; Jordan, H.; Kuzikov, M.; Liu, D.; Zinn, S.; Hohman, S.W.; Schreiber, Y.; Zimmer, B.; Schmidt, M.; Lu, R.; Suo, J.; Zhang, D.-D.; Schäfer, S.M.G.; Hofmann, M.; Yekkirala, A.S.; De Bruin, N.; Parnham, M.J.; Woolf, C.J.; Ji, R.-R.; Scholich, K.; Geisslinger, G. | Journal Article |
2016 | Tetrahydrobiopterin Attenuates DSS-evoked Colitis in Mice by Rebalancing Redox and Lipid Signalling Zschiebsch, K.; Fischer, C.; Pickert, G.; Häussler, A.; Radeke, H.; Grösch, S.; Ferreirós, N.; Geisslinger, G.; Werner, E.R.; Tegeder, I. | Journal Article |
2016 | Thermodynamic properties of leukotriene A4 hydrolase inhibitors Wittmann, S.K.; Kalinowsky, L.; Kramer, J.S.; Bloecher, R.; Knapp, S.; Steinhilber, D.; Pogoryelov, D.; Proschak, E.; Heering, J. | Journal Article |
2016 | Tight-Control der Entzündungsaktivität in der Therapie der frühen Psoriasisarthritis Eine sinnvolle Therapiestrategie zur Verbesserung der Patientenversorgung? Köhm, M. | Journal Article |
2016 | Towards a hit for every target. Editorial Rees, S.; Gribbon, P.; Birmingham, K.; Janzen, W.P.; Pairaudeau, G. | Journal Article |
2016 | Transdermal delivery from liposomal formulations - evolution of the technology over the last three decades Ashtikar, M.; Nagarsekar, K.; Fahr, A. | Journal Article |
2016 | Treatment of enzyme-initiated delignification reaction mixtures with ceramic ultrafiltration membranes: Experimental investigations and modeling approach Busse, N.; Fuchs, F.; Kraume, M.; Czermak, P. | Journal Article |
2016 | Tumour stroma‐derived lipocalin‐2 promotes breast cancer metastasis Ören, B.; Urosevic, J.; Mertens, C.; Mora, J.; Guiu, M.; Gomis, R.R.; Weigert, A.; Schmid, T.; Grein, S.; Brüne, B.; Jung, M. | Journal Article |
2016 | A unifying data-driven model of human olfactory pathology representing known etiologies of dysfunction Lötsch, J.; Ultsch, A.; Hummel, T. | Journal Article |
2016 | UPF1 regulates myeloid cell functions and S100A9 expression by the hnRNP E2/miRNA-328 balance Saul, M.J.; Stein, S.; Grez, M.; Jakobsson, P.-J.; Steinhilber, D.; Suess, B. | Journal Article |
2016 | Use of BLT2 agonists as analgesisc Scholich, Klaus; Zinn, Sebastian; Geisslinger, Gerd; Bruin, Natasja de | Patent |
2016 | Utilizing Regulatory Networks for Pluripotency Assessment in Stem Cells Brändl, B.; Schuldt, B.M.; Böhnke, L.; Keminer, O.; Vaas, L.A.I.; Fischer, R.; Müller, F.-J.; Pless, O. | Journal Article |
2016 | Validation of a distinct psoriatic arthritis risk variant at IL23R Budu-Aggrey, A.; Bowes, J.; Loehr, S.; Uebe, S.; Zervou, M.I.; Helliwell, P.; Ryan, A.W.; Kane, D.; Korendowych, E.; Giardina, E.; Packham, J.; McManus, R.; FitzGerald, O.; McHugh, N.; Behrens, F.; Burkhardt, H.; Huffmeier, U.; Ho, P.; Martin, J.; Castaneda, S.; Goulielmos, G.; Reis, A.; Barton, A. | Abstract |
2016 | Validation of Standardized Questionnaires Evaluating Symptoms of Depression in Rheumatoid Arthritis Patients Englbrecht, M.; Alten, R.; Aringer, M.; Baerwald, C.G.; Burkhardt, H.; Eby, N.; Fliedner, G.; Gauger, B.; Henkemeier, U.; Hofmann, M.W.; Kleinert, S.; Kneitz, C.; Krueger, K.; Pohl, C.; Roske, A.-E.; Schett, G.; Schmalzing, M.; Tausche, A.-K.; Tony, H.P.; Wendler, J. | Journal Article |
2016 | Vasoactive Therapy in Systemic Sclerosis Moinzadeh, P.; Riemekasten, G.; Siegert, E.; Fierlbeck, G.; Henes, J.; Blank, N.; Melchers, I.; Mueller-Ladner, U.; Frerix, M.; Kreuter, A.; Tigges, C.; Lahner, N.; Susok, L.; Guenther, C.; Zeidler, G.; Pfeiffer, C.; Worm, M.; Karrer, S.; Aberer, E.; Bretterklieber, A.; Genth, E.; Simon, J.C.; Distler, J.H.W.; Hein, R.; Schneider, M.; Seitz, C.S.; Herink, C.; Steinbrink, K.; Sárdy, M.; Varga, R.; Mensing, H.; Mensing, C.; Lehmann, P.; Neeck, G.; Fiehn, C.; Weber, M.; Goebeler, M.; Burkhardt, H.; Buslau, M.; Ahmadi-Simab, K.; Himsel, A.; Juche, A.; Koetter, I.; Kuhn, A.; Sticherling, M.; Hellmich, M.; Kuhr, K.; Krieg, T.; Ehrchen, J.; Sunderkoetter, C.; Hunzelmann, N. | Journal Article |
2016 | Vinorelbine and epirubicin share common features with polysialic acid and modulate neuronal and glial functions Loers, G.; Saini, V.; Mishra, B.; Gul, S.; Chaudhury, S.; Wallqvist, A.; Kaur, G.; Schachner, M. | Journal Article |
2016 | Wash-off of the pesticide Pyraclostrobin from plant surfaces in rainfall simulation experiments - development of a laboratory procedure Woermann, Marion : Sures, Bernd; Hennecke, Dieter | Master Thesis |
2016 | Etablierung eines Staphylococcus epidermidis Biofilmmodells zum Screening von Biofilm-abbauenden Enzymen aus Lysobacter Gökçen, A. | Dissertation |
2016 | Komplexe bioinformatische Untersuchungen globaler DNA-Methylierungsmarker im humanen Zell- und Probenmaterial in Bezug zu Schmerz und Opioid-Konsum und epigenetische Regulation des μ-Opioidrezeptor-Gens im humanen Hirngewebe Knothe, C. | Dissertation |