Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2021MultiPaths. A python framework for analyzing multi-layer biological networks using diffusion algorithms
Marín-Llaó, Josep; Mubeen, Sarah; Perera-Lluna, Alexandre; Hofmann-Apitius, Martin; Picart-Armada, Sergio; Domingo-Fernández, Daniel
Journal Article
2021Towards realizing the vision of precision medicine: AI based prediction of clinical drug response
Jong, Johann de; Cutcutache, Ioana; Page, Matthew; Elmoufti, Sami; Dilley, Cynthia; Fröhlich, Holger; Armstrong, Martin
Journal Article
2020Clustering of Alzheimer's and Parkinson's disease based on genetic burden of shared molecular mechanisms
Emon, Mohammad Asif; Heinson, Ashley; Wu, Ping; Domingo-Fernández, Daniel; Sood, Meemansa; Vrooman, Henri; Corvol, Christophe; Scordis, Phil; Hofmann-Apitius, Martin; Fröhlich, Holger
Journal Article
2020Combining Machine Learning and Simulation to a Hybrid Modelling Approach: Current and Future Directions
Rüden, Laura von; Mayer, Sebastian; Sifa, Rafet; Bauckhage, Christian; Garcke, Jochen
Conference Paper
2020Comprehensive analysis of tumor necrosis factor receptor TNFRSF9 (4-1BB) DNA methylation with regard to molecular and clinicopathological features, immune infiltrates, and response prediction to immunotherapy in melanoma
Fröhlich, A.; Loick, S.; Bawden, E.G.; Fietz, S.; Dietrich, J.; Diekmann, E.; Saavedra, G.; Fröhlich, H.; Niebel, D.; Sirokay, J.; Zarbl, R.; Gielen, G.H.; Kristiansen, G.; Bootz, F.; Landsberg, J.; Dietrich, D.
Journal Article
2020A Computational Approach for Mapping Heme Biology in the Context of Hemolytic Disorders
Humayun, Farah; Domingo-Fernández, Daniel; Abisheck Paul George, Ajay; Hopp, Marie-Thérèse; Syllwasschy, Benjamin; Detzel, Milena; Tapley Hoyt, Charles; Hofmann-Apitius, Martin; Imhof, Diana
Journal Article
2020COVID-19 Knowledge Graph: A computable, multi-modal, cause-and-effect knowledge model of COVID-19 pathophysiology
Domingo-Fernández, Daniel; Baksi, Shounak; Schultz, Bruce; Gadiya, Yojana; Kark, Reagon; Raschka, Tamara; Ebeling, Christian; Hofmann-Apitius, Martin; Kodamullil, Alpha Tom
Journal Article
2020The COVID-19 Ontology
Sargsyan, Astghik; Kodamullil, Alpha Tom; Baksi, Shounak; Darms, Johannes; Madan, Sumit; Gebel, Stephan; Keminer, Oliver; Jose, Geena Mariya; Balabin, Helena; DeLong, Lauren Nicole; Kohler, Manfred; Jacobs, Marc; Hofmann-Apitius, Martin
Journal Article
2020Data science in neurodegenerative disease
Golriz Khatami, Sepehr; Mubeen, S.; Hofmann-Apitius, Martin
Journal Article
2020Data-Driven Modeling of Knowledge Assemblies in Understanding Comorbidity Between Type 2 Diabetes Mellitus and Alzheimer’s Disease
Karki, Reagon; Madan, Sumit; Gadiya, Yojana; Domingo-Fernandez, Daniel; Kodamullil, Alpha Tom; Hofmann-Apitius, Martin
Journal Article
2020Differences in cohort study data affect external validation of artificial intelligence models for predictive diagnostics of dementia - lessons for translation into clinical practice
Birkenbihl, Colin; Emon, Mohammad Asif; Vrooman, Henri; Westwood, Sarah; Lovestone, Simon; Hofmann-Apitius, Martin; Fröhlich, Holger
Journal Article
2020Drug2ways: Reasoning over causal paths in biological networks for drug discovery
Rivas-Barragan, Daniel; Mubeen, Sarah; Guim Bernat, Francesc; Hofmann-Apitius, Martin; Domingo-Fernández, Daniel
Journal Article
2020A Landscape Analysis of Standardisation in the Field of Artificial Intelligence
Ziegler, Wolfgang
Journal Article
2020Multicenter Alzheimer's and Parkinson's disease immune biomarker verification study
Brosseron, Frederic; Kolbe, Carl-Christian; Santarelli, Francesco; Carvalho, Stephanie; Antonell, Anna; Castro-Gomez, Sergio; Tacik, Pawel; Namasivayam, Aishwarya Alex; Mangone, Graziella; Schneider, Reinhard; Latz, Eicke; Wüllner, Ullrich; Svenningsson, Per; Sánchez-Valle, Raquel; Molinuevo, José Luis; Corvol, Jean-Christophe; Heneka, Michael T.; Hofmann-Apitius, Martin; Springstubbe, Stephan; Fröhlich, Holger et al.
Journal Article
2020Optimal multiparametric set-up modelled for best survival outcomes in palliative treatment of liver malignancies
Goldstein, Elisha; Yeghiazaryan, Kristina; Ahmad, Ashar; Giordano, Frank A.; Fröhlich, Holger; Golubnitschaja, Olga
Journal Article
2020PathME: Pathway based multi-modal sparse autoencoders for clustering of patient-level multi-omics data
Lemsara, Amina; Ouadfel, Salima; Fröhlich, Holger
Journal Article
2020Proposal of an Architecture for Terminology Management in a Research Project
Mora, Sara; Madan, Sumit; Gebel, Stephan; Giacomini, Mauro
Conference Paper
2020PS4DR: A multimodal workflow for identification and prioritization of drugs based on pathway signatures
Emon, Mohammad Asif; Domingo-Fernandez, Daniel; Tapley Hoyt, Charles; Hofmann-Apitius, Martin
Journal Article
2020Variational Autoencoder Modular Bayesian Networks for Simulation of Heterogeneous Clinical Study Data
Gootjes-Dreesbach, Luise; Sood, Meemansa; Sahay, Akrishta; Hofmann-Apitius, Martin; Fröhlich, Holger
Journal Article