Fraunhofer-Gesellschaft

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Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2018Air-liquid interface in vitro models for respiratory toxicology research: Consensus workshop and recommendations
Lacroix, Ghislaine; Koch, Wolfgang; Ritter, Detlef; Gutleb, Arno C.; Larsen, Søren Thor; Loret, Thomas; Zanetti, Filippo; Constant, Samuel; Chortarea, Savvina; Rothen-Rutishauser, Barbara M.; Hiemstra, Pieter S.; Frejafon, Emeric; Hubert, Philippe; Gribaldo, Laura; Kearns, Peter; Aublant, Jean-Marc; Diabaté, Silvia; Weiss, Carsten; Groot, Antoinette de; Kooter, Ingeborg
Zeitschriftenaufsatz
2018Cerium oxide and barium sulfate nanoparticle inhalation affects gene expression in alveolar epithelial cells type II
Schwotzer, Daniela; Niehof, Monika; Schaudien, Dirk; Kock, Heiko; Hansen, Tanja; Dasenbrock, Clemens; Creutzenberg, Otto H.
Zeitschriftenaufsatz
2018Development and evaluation of an in vitro test system for toxicity screening of aerosols released from consumer products and first application to aerosols from a hair straightening process
Ritter, Detlef; Bitsch, Annette; Elend, Manfred; Schuchardt, Sven; Hansen, Tanja; Brodbeck, Carsten; Knebel, Jan; Fuchs, Anne; Gronewold, Claas; Fautz, Rolf
Zeitschriftenaufsatz
2018A methodology for the assessment of inhalation exposure to aluminium from antiperspirant sprays
Schwarz, Katharina; Pappa, Gerlinde; Miertsch, Heike; Scheel, Julia; Koch, Wolfgang
Zeitschriftenaufsatz
2015Efficacy and safety of inhaled calcium lactate PUR118 in the ozone challenge model - a clinical trial
Holz, Olaf; Biller, Heike; Müller, Meike; Kane, Katie; Rosano, Molly; Hanrahan, John; Hava, David L.; Hohlfeld, Jens M.
Zeitschriftenaufsatz
2013A novel continuous powder aerosolizer (CPA) for inhalative administration of highly concentrated recombinant surfactant protein-C (rSP-C) surfactant to preterm neonates
Pohlmann, Gerhard; Iwatschenko, P.; Koch, Wolfgang; Windt, Horst; Rast, M.; Gama de Abreu, M.; Taut, F.J.H.; Muynck, C. de
Zeitschriftenaufsatz
2013Pulmonary toxicity of printer toner following inhalation and intratracheal instillation
Morimoto, Yasuo; Oyabu, Takako; Horie, Masanori; Kambara, Tatsunori; Izumi, Hiroto; Kuroda, Etsushi; Creuzenberg, Otto; Bellmann, Bernd; Pohlmann, Gerhard; Schuhardt, Sven; Hansen, Tanja; Ernst, Heinrich
Zeitschriftenaufsatz
2011Evaluation of reproductive/developmental and repeated dose (subchronic) toxicity and cytogenetic effects in rats of a roofing asphalt fume condensate by nose-only inhalation
Parker, C.M.; Schreiner, C.A.; Hallmark, N.; Kriech, A.J.; Osborn, L.V.; Fuhst, R.; Buschmann, J.; Ernst, H.; Hansen, T.; Pohlmann, G.; Preiß, A.; Ziemann, C.
Zeitschriftenaufsatz
2010Genotoxicity testing of sulfur dioxide (SO2) in a mouse bone marrow micronucleus test complemented with hematological endpoints
Ziemann, C.; Hansen, T.; Pohlmann, G.; Farrar, D.; Pohlenz-Michel, C.; Tillmann, T.; Mangelsdorf, I.
Zeitschriftenaufsatz
2008Biozidexposition aus Produkten des täglichen Bedarfs
Heger, W.; Hahn, S.; Schneider, K.; Gartiser, S.; Mangelsdorf, I.; Kolossa-Gehring, M.
Zeitschriftenaufsatz
2008Biozidexposition aus Produkten des täglichen Bedarfs
Heger, W.; Hahn, S.; Schneider, K.; Gartiser, S.; Mangelsdorf, I.; Kolossa-Gehring, M.
Zeitschriftenaufsatz
2001Chronic pulmonary effects of respirable methylene diphenyl diisocyanate (MDI) aerosol in rats
Feron, V.J.; Kittel, B.; Kuper, C.F.; Ernst, H.; Rittinghausen, S.; Muhle, H.; Koch, W.; Gamer, A.; Mallett, A.K.; Hoffmann, H.D.
Zeitschriftenaufsatz
199632P-Postlabeling of a DNA adduct derived from 4,4'-methylenedianiline in the olfactory epithelium of rats exposed by inhalation to 4,4'methylenephenyl diisocyanate
Vock, E.H.; Hoymann, H.-G.; Heinrich, U.; Lutz, W.K.
Zeitschriftenaufsatz
1995Untersuchungen zur chronischen Toxizität/Kanzerogenität von 4,4'-Methylendiphenyl-Diisocyanat (MDI). Bd.1
Hoymann, Heinz-Gerd; Buschmann, Jochen; Heinrich, Uwe
Bericht
1994Nasal retention and clearance of wood dust in rats
Creutzenberg, O.; Muhle, H.; Bellmann, B.
Zeitschriftenaufsatz
1993Assessment of pollutant-induced impairment of the pulmonary surfactant system by high-performance liquid chromatography
Klingebiel, R.; Winkeler, H.D.; Drenk, F.; Heinrich, U.
Konferenzbeitrag
1993Does the pulmonary surfactant system yield meaningful parameters in inhalation toxicity studies? A review
Klingebiel, R.; Heinrich, U.
Konferenzbeitrag
1993Generation of complex aerosols
Holländer, W.
Konferenzbeitrag
1993Regeneration, differentiation, and neoplastic transformation of type II alveolar epithelial cells
Thiedemann, K.-U.; Paulini, I.; Lüthe, N.; Kreft, A.; Abel, U.; Glaser, U.; Mohr, U.
Konferenzbeitrag
1992Irreversible pulmonary changes induced in rat lung by dust overload
Bellmann, B.; Creutzenberg, O.; Mermelstein, R.; Muhle, H.
Konferenzbeitrag
1992On the influence of different housing conditions and a sham inhalation exposure of rats on teratological endpoints
Buschmann, J.
Zeitschriftenaufsatz
1991Effects of subchronic exposure to a diisocyanate -MDI- on the pulmonary surfactant system and lung function.
Martin-Carrera, I.; Klingebiel, R.; Hoymann, H.G.; Heinrich, U.
Konferenzbeitrag
1991Immunohistochemistry and morphology of particle-induced pulmonary lesions
Ernst, H.; Nolte, T.; Rittinghausen, S.; Thiedemann, K.-U.
Aufsatz in Buch
1990Clearance and retention of inhaled diesel exhaust particles, carbon black, and titanium dioxide in rats at lung overload conditions
Bellmann, B.; Creutzenberg, O.; Fuhst, R.; Heinrich, U.; Koch, W.; Muhle, H.
Konferenzbeitrag
1990Correlative light, scanning and transmission electron microscopy of rat lungs after short-term exposure to cadmium compounds
Dasenbrock, C.; Paulini, I.; Thiedemann, K.-U.
Konferenzbeitrag
1990Dust overloading of lungs - investigations of various materials, species differences, and irreversibility of effects
Mermelstein, R.; Bellmann, B.; Creutzenberg, O.; Heinrich, U.; Muhle, H.
Konferenzbeitrag
1990Erzeugung und Überwachung von Aerosolen für Inhalationsexperimente
Koch, W.
Zeitschriftenaufsatz
1990Histological observations and morphometric analysis in lungs of hamsters after long term inhalation of cadmium compounds
Aufderheide, M.; Dasenbrock, C.; Ernst, H.; Fuhst, R.; Heinrich, U.; Mohr, U.; Peters, L.; Rittinghausen, S.
Konferenzbeitrag
1990Investigation of irritating properties of inhaled CrVI with possible influence on its charcinogen action.
Steinhoff, D.; Glaser, U.; Hochrainer, D.
Konferenzbeitrag
1990Irreversible pulmonary changes after dust overloading of lungs in rats
Bellmann, B.; Creutzenberg, O.; Mermelstein, R.; Muhle, H.
Konferenzbeitrag
1990Qualitative and quantitative ultrastructural investigations in hamster lungs after chronic inhalation of cadmium compounds
Thiedemann, K.-U.; Kreft, A.; Abel, U.; Dasenbrock, C.; Fuhst, R.; Peters, L.; Heinrich, U.; Mohr, U.
Konferenzbeitrag
1990Quantification of hyperplastic areas in hamster lungs after chronic inhalation of different cadmium compounds
Aufderheide, M.; Heinrich, U.; Mohr, U.; Thiedemann, K.-U.
Zeitschriftenaufsatz
1990Recovery behaviour after dust overloading of lungs in rats
Mermelstein, R.; Bellmann, B.; Creutzenberg, O.; Muhle, H.
Zeitschriftenaufsatz
1990Subchronic inhalation study of toner in rats
Morrow, P.; Kilpper, R.; MacKenzie, J.; Mermelstein, R.; Bellmann, B.; Creutzenberg, O.; Fuhst, R.; Koch, W.; Mohr, U.; Muhle, H.; Takenaka, S.
Zeitschriftenaufsatz
1990Toxicokinetics and carcinogenicity of man-made fibres
Bellmann, B.
Konferenzbeitrag
1990Ultrastructural observations in mouse lungs after short term inhalation of cadmium compounds
Dasenbrock, C.; Paulini, I.; Thiedemann, K.-U.
Konferenzbeitrag
1990Ultrastructural observations in mouse lungs after short term inhalation of cadmium compounds
Dasenbrock, C.; Paulini, I.; Thiedemann, K.-U.
Zeitschriftenaufsatz
1990Ultrastructure of hamster and rat lungs after chronic inhalation exposure to cadmium compounds
Thiedemann, K.-U.; Kreft, A.; Lüthe, N.; Heinrich, U.; Glaser, U.; Abel, U.
Konferenzbeitrag
1989Comparative long-term animal inhalation studies using various particulate matter - objectives, experimental design and preliminary results
Dasenbrock, C.; Fuhst, R.; Heinrich, U.; Muhle, H.; Peters, L.; Pott, F.
Zeitschriftenaufsatz
1989The effect of automotive exhaust exposure on the carcinogenicity of dipentylnitrosamine -DPN- in the respiratory tract of rats
Fuhst, R.; Heinrich, U.; Mohr, U.; Peters, L.
Zeitschriftenaufsatz
1989An experimental animal study for risk assessment of indoor air pollutants.
Glaser, U.; Hochrainer, D.; Klein, W.; Otto, F.
Zeitschriftenaufsatz
1989Inhalation experiments on retention and lung clearance of asbestos in combination with cigarette-smoking
Bellmann, B.; Muhle, H.; Pott, F.; Spurny, K.R.
Konferenzbeitrag
1989Investigation on the carcinogenic effects of various cadmium compounds after inhalation exposure in hamsters and mice
Dasenbrock, C.; Ernst, H.; Heinrich, U.; König, H.; Peters, L.; Rittinghausen, S.
Zeitschriftenaufsatz
1989Lung response to test toner upon 2 year inhalation exposure in rats
Kilpper, R.; MacKenzie, J.; Dasenbrock, C.; Mermelstein, R.; Mohr, U.; Morrow, P.E.; Muhle, H.; Takenaka, S.
Zeitschriftenaufsatz
1989Pulmonary function changes in rats after chronic and subchronic inhalation exposure to various particulate matter
Heinrich, U.; Hoymann, H.-G.; Mermelstein, R.; Muhle, H.
Zeitschriftenaufsatz
1989Quantification of proliferation lesions in hamster lungs after chronic exposure to cadmium aerosols
Aufderheide, M.; Riebe, M.; Kohler, M.; Thiedemann, K.-U.
Konferenzbeitrag
1989Reversibility of biochemical and cytological alterations in bronchoalveolar lavagate upon cessation of dust exposure
Kilpper, R.; Bellmann, B.; Creutzenberg, O.; Mermelstein, R.; Morrow, P.E.; Muhle, H.
Zeitschriftenaufsatz
1989Reversibility of clearance impairment after subchronic test toner inhalation
Kilpper, R.; Bellmann, B.; Creutzenberg, O.; Mermelstein, R.; Morrow, P.E.; Muhle, H.
Zeitschriftenaufsatz
1989Ultrastructural observation in hamster and rat lungs after chronic inhalation of cadmium compounds
Glaser, U.; Heinrich, U.; Kreft, A.; Lüthe, N.; Paulini, I.; Thiedemann, K.-U.
Konferenzbeitrag
1988Carcinogenicity of cadmium - overview of experimental and epidemiological results and their influence on recommendations for maximum concentrations in the occupational area
Heinrich, U.
Konferenzbeitrag
1988Exposure facilities and aerosol generation and characterization for inhalation experiments
Holländer, W.
Aufsatz in Buch
1988Investigation of the lung carcinogenic potential of sodium dichromate and Cr
Glaser, U.; Hochrainer, D.; Oldiges, H.
Konferenzbeitrag
1988Investigation of the lung carcinogenic potentials of sodium dichromate and Cr (VI/III) oxide aerosols in wistar rats
Glaser, U.; Hochrainer, D.; Oldiges, H.
Konferenzbeitrag
1988Long-term inhalation study of test toner in rats.
Kilpper, R.; MacKenzie, J.; Morrow, P.; Dasenbrock, C.; Koch, W.; Mermelstein, R.; Mohr, U.; Muhle, H.
Konferenzbeitrag
1988Morphological effects of nickel powders on the lung of Syrian golden hamsters
Bellmann, B.; Creutzenberg, O.; Mohr, U.; Muhle, H.; Takenaka, S.
Zeitschriftenaufsatz
1988Overloading of lung clearance chronic exposure of experimental animals to particle
Bellmann, B.; Heinrich, U.; Muhle, H.
Zeitschriftenaufsatz
1988Pulmonary deposition, clearance and retention of test toner, TIO2 and quartz during a long term inhalation study in rats.
Kilpper, R.; Mackenzie, J.; Morrow, P.; Bellmann, B.; Creutzenberg, O.; Mermelstein, R.; Muhle, H.; Stoeber, W.
Konferenzbeitrag
1988A subchronic inhalation study of a special test toner in rats.
Kilpper, R.; Creutzenberg, O.; Mermelstein, R.; Mohr, U.; Muhle, H.; Takenaka, S.
Konferenzbeitrag
1988Toxicity and carcinogenic risk after long term inhalation of cadmium compounds in Wistar-rats.
Glaser, U.; Hochrainer, D.; Oldiges, H.
Konferenzbeitrag
1987Untersuchungen über den Einfluß nicht-toxischer Stäube auf die Lungenreinigung und die Funktion der Alveolarmakrophagen
Koenig, H.; Lohmann-Matthes, M.-L.; Bellmann, B.; Creutzenberg, O.; Koch, W.; Muhle, H.; Takenaka, S.
Buch
1986Alveolar distribution of fly ash and of titanium dioxide after long-term inhalation by Wistar rats
Takenaka, S.; Dornhöfer-Takenaka, H.; Muhle, H.
Zeitschriftenaufsatz
1986Bioavailability indicators of inhaled cadmium compounds.
Kloeppel, H.; Glaser, U.; Hochrainer, D.
Zeitschriftenaufsatz
1986Clearance of inhaled insoluble particle from the alveolar regions via the extraalveolar perivascular sheath
Muhle, H.; Takenaka, S.
Konferenzbeitrag
1986The generation and the measurement of dry aerosol in large-scale inhalation experiments
Koch, W.; Lödding, H.; Muhle, H.; Önning, G.
Zeitschriftenaufsatz
1986Inhalation and injection experiments in rats for testing carcinogenicity of MMMF
Ziem, U.; Bellmann, B.; Muhle, H.; Pott, F.; Takenaka, S.
Konferenzbeitrag
1986The inhalative toxicity of different cadmium compounds in rats.
Glaser, U.; Oldiges, H.
Konferenzbeitrag
1986Langzeit-Inhalationsversuch mit vier verschiedenen Cadmium-Verbindungen an Ratten
Glaser, U.; Hochrainer, D.; Oldiges, H.
Zeitschriftenaufsatz
1986Pulmonale Clearance von inhalierten Partikeln in Abhängigkeit von der Partikelgröße.
Bellmann, B.; Muhle, H.
Zeitschriftenaufsatz
1985Carcinogeicity of sodium dichromate and chromium
Kloeppel, H.; Glaser, U.; Hochrainer, D.; Oldiges, H.
Zeitschriftenaufsatz
1984Alveolar proteinosis induced in rats by long-term inhalation of nickel oxide
Hochrainer, D.; Oldiges, H.; Takenaka, S.
Konferenzbeitrag
1983Carcinogenicity of cadmium chloride aerosols in w-rats
Takenaka, S.; Oldiges, H.; Koenig, H.; Oberdoerster, G.; Hochrainer, D.
Konferenzbeitrag
1983Generation of aerosols from heavy metals for inhalation experiments.
Hochrainer, D.
Aufsatz in Buch
1983Lung carcinomas in rats after low level cadmium chloride inhalation
Koenig, H.; Oberdoerster, G.; Hochrainer, D.; Oldiges, H.; Takenaka, S.
Aufsatz in Buch
1982Carcinogenicity of cadmium-aerosols in wistar-rats
Koenig, H.; Oberdoerster, G.; Hochrainer, D.; Oldiges, H.; Takenaka, S.
Aufsatz in Buch
1981Ultrastructural alterations in the livers of golden hamsters following experimental chronic inhalation of diluted diesel exhaust emission
Meiß, R.; Robenek, H.; Schubert, M.; Themann, H.; Heinrich, U.
Zeitschriftenaufsatz