Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2019Human Pluripotent Stem Cell-Derived Multipotent Vascular Progenitors of the Mesothelium Lineage Have Utility in Tissue Engineering and Repair
Colunga, Thomas; Hayworth, Miranda; Kress, Sebastian; Reynolds, David M.; Chen, Luoman; Nazor, Kristopher L.; Baur, Johannes; Singh, Amar M.; Loring, Jeanne F.; Metzger, Marco; Dalton, Stephen
Journal Article
2018Advanced dynamic cell and tissue culture
Hansmann, Jan; Egger, Dominik; Kasper, Cornelia
Journal Article
2018A combined tissue-engineered/in silico signature tool patient stratification in lung cancer
Göttlich, Claudia; Kunz, Meik; Zapp, Cornelia; Nietzer, Sarah L.; Walles, Heike; Dandekar, Thomas; Dandekar, Gudrun
Journal Article
2018Evaluation of a miniaturized biologically vascularized scaffold in vitro and in vivo
Kress, Sebastian; Baur, Johannes; Otto, Christoph; Burkard, Natalie; Braspenning, Joris; Walles, Heike; Nickel, Joachim; Metzger, Marco
Journal Article
2018Recombinant collagen I peptide microcarriers for cell expansion and their potential use as cell delivery system in a bioreactor model
Suarez Muñoz, Melva; Confalonieri, Davide; Walles, Heike; Dongen, Elisabeth M.W.M. van; Dandekar, Gudrun
Journal Article
2018TGF-β family co-receptor function and signaling
Nickel, Joachim; Dijke, Peter ten; Müller, Thomas D.
Journal Article
2018A three-dimensional hybrid pacemaker electrode seamlessly integrates into engineered, functional human cardiac tissue in vitro
Weigel, Tobias; Schmitz, Tobias; Pfister, Tobias; Gaetzner, Sabine; Jannasch, Maren; Al-Hijailan, Reem; Schürlein, Sebastian; Suliman, Salwa; Mustafa, Kamal; Hansmann, Jan
Journal Article
2018Tissue Mimicry in Morphology and Composition Promotes Hierarchical Matrix Remodeling of Invading Stem Cells in Osteochondral and Meniscus Scaffolds
Stuckensen, Kai; Schwab, Andrea; Knauer, Markus; Muiños-López, Emma; Ehlicke, Franziska; Reboredo, Jenny W.; Granero-Moltó, Froilán; Gbureck, Uwe; Prósper, Felipe; Walles, Heike; Groll, Jürgen
Journal Article
2017Freeze-drying as a novel biofabrication method for achieving a controlled microarchitecture within large, complex natural biomaterial scaffolds
Brougham, Claire M.; Levingstone, Tanya J.; Shen, Nian; Cooney, Gerard M.; Jockenhövel, Stefan; Flanagan, Thomas C.; O'Brien, Fergal J.
Journal Article
2017Human barrier models for the in vitro assessment of drug delivery
Schweinlin, Matthias; Rossi, Angela; Lodes, Nina; Lotz, Christian; Hackenberg, Stephan; Steinke, Maria; Walles, Heike; Groeber, Florian
Journal Article
2017Laser processing of dry, wet and immersed polyamide nanofiber nonwovens with different laser sources
Götze, M.; Farhan, A.M.; Kürbitz, T.; Krimig, O.; Henning, S.; Heilmann, A.; Hillrichs, G.
Journal Article
2017A pancreas‐specific ECM scaffold – human iPS cell culture and pancreatic differentiation goes 3D
Berger, Constantin; Bjørlykke, Yngvild; Mühlemann, Markus; Ræder, Helge; Walles, Heike; Metzger, Marco; Zdzieblo, Daniela
Abstract
2017Raman Spectroscopy
Marzi, Julia; Brauchle, Eva; Carvajal Berrio, Daniel A.; Layland, Shannon L.; Schenke-Layland, Katja
Book Article
2017Tissue Engineering of primary human in vitro models – Influence of mechanical and biochemical stimulation on tissue functionality
Appelt-Menzel, Antje; Zdzieblo, Daniela; Schürlein, Sebastian; Schwarz, Thomas; Hansmann, Jan; Metzger, Marco; Walles, Heike
Abstract
2017A versatile modular bioreactor platform for Tissue Engineering
Schürlein, Sebastian; Schwarz, Thomas; Krziminski, Steffan; Gätzner, Sabine; Hoppensack, Anke; Schwedhelm, Ivo; Schweinlin, Matthias; Walles, Heike; Hansmann, Jan
Journal Article
20163D printing - a key technology for tailored biomedical cell culture lab ware
Schmieder, Florian; Ströbel, Joachim; Rösler, Mechthild; Grünzner, Stefan; Hohenstein, Bernd; Klotzbach, Udo; Sonntag, Frank
Journal Article
2016Challenges in tissue engineering - towards cell control inside artificial scaffolds
Emmert, Martin; Witzel, Patrick; Heinrich, Doris
Journal Article
2016A first vascularized skin equivalent for as an alternative to animal experimentation
Groeber, Florian; Engelhardt, Lisa; Lange, Julia; Kurdyn, Szymon; Schmid, Freia F.; Rücker, Christoph; Mielke, Stephan; Walles, Heike; Hansmann, Jan
Journal Article
2016Hydroxyapatite-modified gelatin bioinks for bone bioprinting
Wenz, Annika; Janke, Katharina; Hoch, Eva; Tovar, Günter; Borchers, Kirsten; Kluger, Petra
Journal Article
2016In vivo host response and degradation of copolymer scaffolds functionalized with nanodiamonds and bone morphogenetic protein 2
Suliman, Salwa; Sun, Yang; Pedersen, Torbjorn O.; Xue, Ying; Nickel, Joachim; Waag, Thilo; Finne-Wistrand, Anna; Steinmüller-Nethl, Doris; Krueger, Anke; Costea, Daniela E.; Mustafa, Kamal
Journal Article
2016Isotropic versus bipolar functionalized biomimetic artificial basement membranes and their evaluation in long-term human cell co-culture
Rossi, Angela; Wistlich, Laura; Heffels, Karl-Heinz; Walles, Heike; Groll, Jürgen
Journal Article
2016Rapid Prototyping
Gurr, M.; Mülhaupt, R.
Book Article
2016Synthese und Charakterisierung partiell degradierbarer Hybridpolymere für biomedizinische Anwendungen
Obel, Kerstin
: Sextl, G.; Tacke, R.
Dissertation
2015Biomaterialentwicklung für die Herstellung dreidimensionaler, dynamisch kultivierter, künstlicher Blutgefäße als Testsystem oder Implantat
Novosel, Esther C.
Dissertation
2015Generation and assessment of functional biomaterial scaffolds for applications in cardiovascular tissue engineering and regenerative medicine
Hinderer, Svenja; Brauchle, Eva; Schenke-Layland, Katja
Journal Article
2015Generation of a three-dimensional full thickness skin equivalent and automated wounding
Rossi, Angela; Appelt-Menzel, Antje; Kurdyn, Szymon; Walles, Heike; Groeber, Florian
Journal Article
2015The multi-organ chip - A microfluidic platform for long-term multi-tissue coculture
Materne, Eva-Maria; Maschmeyer, Ilka; Lorenz, Alexandra K.; Horland, Reyk; Schimek, Katharina; Busek, Mathias; Sonntag, Frank; Lauster, Roland; Marx, Uwe
Journal Article
2015A perfusion bioreactor system efficiently generates cell-loaded bone substitute materials for addressing critical size bone defects
Kleinhans, Claudia; Mohan, Ramkumar Ramani; Vacun, Gabriele; Schwarz, T.; Haller, B.; Sun, Yang; Kahlig, A.; Kluger, Petra; Finne-Wistrand, Anna.; Walles, Heike; Hansmann, Jan
Journal Article
2015Prospects for regenerative medicine approaches in women's health
Schenke-Layland, Katja; Brucker, Sara Y.
Journal Article
2015Stem cell-based tissue replacement after stroke
Janowski, Miroslaw; Wagner, Daniel-Christoph; Boltze, Johannes
Journal Article
2014Chrondrogenic predifferentiation of human mesenchymal stem cells in collagen type I hydrogels
Fensky, Florian; Reichert, Johannes C.; Traube, Andrea; Rackwitz, Lars; Siebenlist, Sebastian; Nöth, Ulrich
Journal Article
2014Comprehensive characterization of chondrocyte cultures in plasma and whole blood biomatrices for cartilage tissue engineering
Schulz, Ronny Maik; Haberhauer, Marcus; Zernia, Göran; Pösel, Claudia; Thümmler, Christian; Somerson, Jeremy S.; Huster, Daniel
Journal Article
2014Engineering of a bio-functionalized hybrid off-the-shelf heart valve
Hinderer, Svenja; Seifert, Jan; Votteler, Miriam; Shen, Nian; Rheinlaender, Johannes; Schäffer, Tilman E; Schenke-Layland, Katja
Journal Article
2013An in vitro model of the renal proximal tubule composed of small intestinal submucosa (SIS) and human kidney-derived cells (hKDCs)
Hoppensack, Anke; Schanz, Johanna; Kazanecki, Christian; Colter, David; Walles, Heike
Journal Article, Conference Paper
2012Development of full-thickness skin equivalents including immunological cell types
Kurdyn, Szymon; Weil, Frederick; Nickel, Joachim; Mielke, Stephan; Walles, Heike
Abstract
2012Raman spectroscopy for the non-contact and non-destructive monitoring of collagen damage within tissues
Votteler, M.; Berrio, D.A.C.; Pudlas, M.; Walles, H.; Stock, U.A.; Schenke-Layland, K.
Journal Article
2012Tissue Engineering: Menschliche Gewebe aus dem Labor
Schanz, J.; Walles, H.; Walles, T.
Journal Article
2012Werkstofftrends: Bioaktive Glaswerkstoffe
Reschke, Stefan; Grüne, Matthias; Kohlhoff, Jürgen
Journal Article
2011Artificial small diameter blood vessels based on new biofunctionalized 3D-printable polymers
Novosel, Esther; Klechowitz, Nadine; Meyer, Wolfdietrich; Schuh, Christian; Borchers, Kirsten; Wegener, Michael; Krüger, Hartmut; Walles, Heike; Hirth, Thomas; Tovar, Günter; Kluger, Petra
Journal Article, Conference Paper
2011Vollautomatisierte Herstellung von Gewebemodellen
Walles, Heike
Journal Article
2010Cell isolation from lung tumour tissue
Appelt, A.; Jany, C.; Heymer, A.
Journal Article
2010Characterization of human skin cells for tissue engineering applications by Raman spectroscopy
Pudlas, M.; Koch, S.; Bolwien, C.; Walles, H.
Conference Paper
2010Electrospun poly(D/L-lactide-co-L-lactide) hybrid matrix: A novel scaffold material for soft tissue engineering
Kluger, P.J.; Wyrwa, R.; Weisser, J.; Maierle, J.; Votteler, M.; Rode, C.; Schnabelrauch, M.; Walles, H.; Schenke-Layland, K.
Journal Article
2010Facilitated non-invasive visualization of collagen and elastin in blood vessels
Fritze, O.; Schleicher, M.; König, K.; Schenke-Layland, K.; Stock, U.A.; Harasztosi, C.
Journal Article
2010Impact of heart valve decellularization on 3-D ultrastructure, immunogenicity and thrombogenicity
Zhou, J.; Fritze, O.; Schleicher, M.; Wendel, H.-P.; Schenke-Layland, K.; Harasztosi, C.; Hu, S.; Stock, U.A.
Journal Article
2010New method for scaffold fabrication for tissue engineering by combination of inkjet-printing and multiphoton
Refle, Oliver; Graf, Careen; Engelhardt, Sascha; Visotschnig, Roland
Conference Paper
2010The performance of ice-free cryopreserved heart valve allografts in an orthotopic pulmonary sheep model
Lisy, M.; Pennecke, J.; Brockbank, K.G.M.; Fritze, O.; Schleicher, M.; Schenke-Layland, K.; Kaulitz, R.; Riemann, I.; Weber, C.N.; Braun, J.; Mueller, K.E.; Fend, F.; Scheunert, T.; Gruber, A.D.; Albes, J.M.; Huber, A.J.; Stock, U.A.
Journal Article
2010Raman spectroscopy as a tool for quality and sterility analysis for tissue engineering applications like cartilage transplants
Pudlas, M.; Koch, S.; Bolwien, C.; Walles, H.
Journal Article
2010Semiconducting to metallic-like boron doping of nanocrystalline diamond films and its effect on osteoblastic cells
Kromka, A.; Grausova, L.; Bacáková, L.; Vacik, J.; Rezek, B.; Vanecek, M.; Williams, O.A.; Haenen, K.
Journal Article, Conference Paper
2010Simplified pulse reactor for real-time long-term in vitro testing of biological heart valves
Schleicher, M.; Sammler, G.; Schmauder, M.; Fritze, O.; Huber, A.J.; Schenke-Layland, K.; Ditze, G.; Stock, U.A.
Journal Article
2010Stem cell microenvironments - unveiling the secret of how stem cell fate is defined
Votteler, M.; Kluger, P.J.; Walles, H.; Schenke-Layland, K.
Journal Article
2010A system for the rapid detection of bacterial contamination in cell-based therapeutica
Bolwien, C.; Erhardt, C.; Sulz, G.; Thielecke, H.; Johann, R.; Pudlas, M.; Walles, H.; Mertsching, H.; Koch, S.
Conference Paper
2010Technologie und Werkstoffinnovationen für medizinische Stützstrukturen
Neugebauer, Reimund
Journal Article
2009Discrimination of microorganisms and cells in tissue engineering by Raman spectroscopy
Koch, S.; Dreiling, M.; Gutekunst, M.; Bolwien, C.; Thielecke, H.; Mertsching, H.
Conference Paper
2009Morphogenetic and regulatory mechanisms during developmental chondrogenesis
Quintana, Lluís; Nieden, Nicole zur; Semino, Carlos E.
Journal Article
2009Raman spectroscopy: a non-invasive analysis tool for studies of living cells
Pudlas, M.; Koch, S.; Bolwien, C.; Mertsching, H.
Abstract
2008Manufacturing and replication of cell aligning micro structures
Brecher, C.; Klar, R.; Pretzsch, F.; Wenzel, C.
Conference Paper
2008Micro structure surface functionalisation for tissue engineering applications - A systematic integrated approach towards high volume production
Brecher, C.; Wenzel, C.; Klar, R.; Pretzsch, F.
Conference Paper
2008Rapid detection of bacterial contamination in cell or tissue cultures based on Raman spectroscopy
Bolwien, C.; Sulz, G.; Becker, S.; Thielecke, H.; Mertsching, H.; Koch, S.
Conference Paper
2007Funktionalisierte Polymer-Feinstrukturen für Medizintechnik und Biotechnologie
Wagenknecht, T.; Jäger, M.; Sonntag, F.
Conference Paper
2007Invasive and noninvasive methods for studying pulmonary function in mice
Glaab, T.; Taube, C.; Braun, A.; Mitzner, W.
Journal Article
2006Vaskularisierte Trägersysteme für in vitro Testsysteme
Mertsching, H.; Hansmann, J.; Schanz, J.; Linke, K.; Brenner, M.; Michaelis, J.; Walles, T.
Conference Paper
2005Biotechnologie
Kernchen, R.
Journal Article
2001Aufbau eines humanen dreidimensionalen Hautäquivalents als Textsystem
Merkle, M.-L.
Dissertation
1999Constructing an in vitro cornea from cultures of the three specific corneal cell types
Schneider, A.; Meier-Reif, K.; Graeve, T.
Journal Article