Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2016Spontaneous malignant craniopharyngioma in an aged Wistar rat
Heinrichs, Martin; Ernst, Heinrich
Journal Article
2013Osteoblast and bone tissue response to surface modified zirconia and titanium implant materials
Kohal, R.J.; Bächle, M.; Att, W.; Chaar, S.; Altmann, B.; Renz, A.; Butz, F.
Journal Article
2012Lung function measurements in rodents in safety pharmacology studies
Hoymann, Heinz Gerd
Journal Article
2011Histologische und elektronenmikroskopische Untersuchungen der Lunge nach Inhalation von Titandioxid-Nanopartikeln bzw. -Feinpartikeln bei der Ratte
Eydner, M.
: Baumgärtner, W.; Pfarrer, C.
Dissertation
2011Relationship of pulmonary toxicity and carcinogenicity of fine and ultrafine granular dusts in a rat bioassay
Kolling, A.; Ernst, H.; Rittinghausen, S.; Heinrich, U.
Journal Article
2011RITA - Registry of Industrial Toxicology Animal data: The application of historical control data for Leydig cell tumors in rats
Nolte, T.; Rittinghausen, S.; Kellner, R.; Karbe, E.; Kittel, B.; Rinke, M.; Deschl, U.
Journal Article
2010Development and validation of an analytical method for determination of 3-chloropropane-1,2-diol in rat blood and urine by gas chromatography-mass spectrometry in negative chemical ionization mode
Berger-Preiß, E.; Gerling, S.; Apel, E.; Lampen, A.; Creutzenberg, O.
Journal Article
2010Ex vivo Comet Assay und Mikrokerntest an primären Typ II Zellen der Ratte
Reinke, J.
: Pfitzner, R. (Prüfer); Hansen, T.
Bachelor Thesis
2009Juvenile animal toxicity study designs to support pediatric drug development
Cappon, G.D.; Buschmann, J.; Feuston, M.H.; Fisher, J.E.; Hew, K.W.; Hoberman, A.M.; Ooshima, Y.; Stump, D.G.; Hurt, M.E.
Journal Article
2008An analysis of the results from two-generation reproduction toxicity studies to assess the value of mating animals of the second (F1) generation for the detection of adverse treatment-related effects on reproductive performance
Myers, D.P.; Willoughby, C.R.; Bottomley, A.M.; Buschmann, J.
Journal Article, Conference Paper
2008Comparison of primary lung tumor incidences in the rat evaluated by the standard microscopy method and by multiple step sections
Kolling, A.; Ernst, H.; Rittinghausen, S.; Heinrich, U.; Pott, F.
Journal Article
2008Cross-talk between aryl hydrocarbon receptor and mitogen-activated protein kinase signaling pathway in liver cancer through c-raf transcriptional regulation
Borlak, J.; Jenke, H.S.
Journal Article
2008Elastase-induced lung emphysema in rats is not reduced by hematopoietic growth factors when applied preventionally
Schmiedl, A.; Lempa, T.; Hoymann, H.G.; Rittinghausen, S.; Popa, D.; Tschernig, T.; Fehrenbach, H.; Pabst, R.; Hoeper, M.M.; Hohlfeld, J.M.
Journal Article
2008In vitro and in vivo screening of the cytotoxic, pro-inflammatory and genotoxic potential of quartz-containing ceramic dusts
Ziemann, C.; Hansen, T.; Ernst, H.; Jackson, P.; Brown, R.; Creutzenberg, O.
Journal Article, Conference Paper
2008Toxicity of a quartz with occluded surfaces in a 90-day intratracheal instillation study in rats
Creutzenberg, O.; Hansen, T.; Ernst, H.; Muhle, H.; Oberdörster, G.; Hamilton, R.
Journal Article
2007Invasive and noninvasive lung function measurements in rodents
Hoymann, H.G.
Journal Article
2006Collection, validation and generation of bitumen fumes for inhalation studies in rats. Pt.1: Workplace samples and validation criteria
Preiß, A.; Koch, W.; Kock, H.; Raabe, M.; Pohlmann, G.
Journal Article
2006Collection, validation and generation of bitumen fumes for inhalation studies in rats. Pt.2: Collection of bitumen fumes from storage tanks
Pohlmann, G.; Preiß, A.; Levsen, K.; Raabe, M.; Koch, W.
Journal Article
2006Der Einfluss der extrazellulären Matrix auf die Regulation leberspezifischer Transkriptionsfaktoren in Kulturen primärer Rattenhepatozyten und ihre Bedeutung für die zelluläre Differenzierung
Rittelmeyer, I.
Thesis
2006Einfluss von Budesonid auf die Surfactant-Dysfunktion beim Asthma bronchiale am Tiermodell der Brown-Norway-Ratte
Detmer, A.A.
Dissertation
2006The kinetics of transcriptomic changes induced by cigarette smoke in rat lungs reveals a specific program of defense, inflammation, and circadian clock gene expression
Gebel, S.; Gerstmayer, B.; Kuhl, P.; Borlak, J.; Meurrens, K.; Müller, T.
Journal Article
2006Primary rat alveolar epithelial cells for use in biotransformation and toxicity studies
Hansen, T.; Blickwede, M.; Borlak, J.
Journal Article
2006Untersuchungen zur Expression von Cytokin-, Adhäsion- und Apoptose kodierenden Genen nach isogener und allogener Herztransplantation in der Ratte
Kundu, S.
Dissertation
2005Pathogenetische und immunbiologische Untersuchungen zur Frage: Ist die Extrapolation der Staubkanzerogenität von der Ratte auf den Menschen gerechtfertigt? Teil II: Histologie
Ernst, H.; Kolling, A.; Bellmann, B.; Rittinghausen, S.; Heinrich, U.; Pott, F.
Report
2003Calibration study on subchronic inhalation toxicity of man-made vitreous fibers in rats
Bellmann, B.; Muhle, H.; Creutzenberg, O.; Ernst, H.; Müller, M.; Bernstein, D.M.; Riego Sintes, J.M.
Journal Article
2003Effects of Di-n-Butylamine on the respiratory system of wistar (WU) rats after subchronic inhalation
Buschmann, J.; Dasenbrock, C.; Fuhst, R.; Pohlmann, G.; Bartsch, W.; Creutzenberg, O.; Ernst, H.; Ketkar, M.; Schneider, B.; Ott, H.
Journal Article
2003Increase of inactive intra-alveolar surfactant subtypes in lungs of asthmatic Brown Norway rats
Schmiedl, A.; Hoymann, H.-G.; Ochs, M.; Menke, A.; Fehrenbach, A.; Krug, N.; Tschernig, T.; Hohlfeld, J.M.
Journal Article
2003Inhibition of induced chemoresistance by cotreatment with (E)-5-(2-Bromovinyl)-2'-Deoxyuridine (RP101)
Fahrig, R.; Heinrich, J.-C.; Nickel, B.; Wilfert, F.; Leisser, C.; Krupitza, G.; Praha, C.; Sonntag, D.; Fiedler, B.; Scherthan, H.; Ernst, H.
Journal Article
2003Revised guides for organ sampling and trimming in rats and mice - Part 1
Ruehl-Fehlert, C.; Kittel, B.; Morawietz, G.; Deslex, P.; Keenan, C.; Mahrt, C.R.; Nolte, T.; Robinson, M.; Stuart, B.P.; Deschl, U.
Journal Article
2003Surfactant homeostasis is maintained in vivo during Keratinocyte growth factor-induced rat lung type II cell hyperplasia
Fehrenbach, A.; Bube, C.; Hohlfeld, J.M.; Stevens, P.; Tschernig, T.; Hoymann, H.G.; Krug, N.; Fehrenbach, H.
Journal Article
2003Tumours of the pituitary pars intermedia with associated bilateral adrenocortical hyperplasia in aging male rats
Heinrichs, M.; Bube, A.; Ernst, H.; Troschau, G.; Friderichs-Gromoll, S.
Journal Article
2002Altered cytochrome P450 monooxygenase activity in heart tissue of spontaneously hypertensive rats
Thum, T.; Borlak, J.
Conference Paper, Journal Article
2002Compound profiling using CDNA array based differential gene expression of human and rat hepatocytes
Hansen, T.; Dangers, M.; Borlak, J.; Gerstmayer, B.; Tomiuk, S.; Hofmann, K.; Hübel, F.; Bosio, A.
Journal Article
2002Late allergic response in sensitized rats
Hoymann, H.G.; Glaab, T.; Hohlfeld, J.; Korolewitz, R.; Hecht, M.; Krug, N.
Conference Paper
2002The north american control animal database: a resource based on standardized nomenclature and diagnostic criteria
Keenan, C.; Hughes-Earle, A.; Case, M.; Stuart, B.P.; Lake, S.; Mahrt, C.; Halliwell, W.; Westhouse, R.; Elwell, M.; Morton, D.; Morawietz, G.; Rittinghausen, S.; Deschl, U.; Mohr, U.
Journal Article
2002Novel phase I and phase II metabolites of Verapamil identified in cell cultures of rat hepatocytes by LC-MS(n)
Walles, M.; Thum, T.; Levsen, K.; Borlak, J.
Conference Paper, Journal Article
2002Pulmonary inflammation in rats after intratracheal instillation of quartz, amorphous SiO2, carbon black, and coal dust and the influence of poly-2-vinylpyridine-N-oxide (PVNO)
Ernst, H.; Rittinghausen, S.; Bartsch, W.; Creutzenberg, O.; Dasenbrock, C.; Görlitz, B.-D.; Hecht, M.; Kairies, U.; Muhle, H.; Müller, M.; Heinrich, U.; Pott, F.
Journal Article
2002The value of historical control data: scientific advantages for pathologists, industry and agencies
Deschl, U.; Kittel, B.; Rittinghausen, S.; Morawietz, G.; Kohler, M.; Mohr, U.; Keenan, C.
Journal Article
2001Chronic pulmonary effects of respirable methylene diphenyl diisocyanate (MDI) aerosol in rats
Feron, V.J.; Kittel, B.; Kuper, C.F.; Ernst, H.; Rittinghausen, S.; Muhle, H.; Koch, W.; Gamer, A.; Mallett, A.K.; Hoffmann, H.D.
Journal Article
2001Cross-fostering inhalation toxicity study with hcfc-123 in lactating sprague-dawley rats
Buschmann, J.; Bartsch, W.; Dasenbrock, C.; Fuhst, R.; Pohlmann, G.; Preiß, A.; Berger-Preiß, E.
Journal Article
2001Effects of nonfibrous particles on ceramic fiber (RCF1) toxicity in rats
Bellman, B.; Muhle, H.; Creutzenberg, O.; Ernst, H.; Brown, R.C.; Sebastien, P.
Journal Article
2001Gene expression and testosterone metabolism in distinct regions of the rat heart
Thum, T.; Borlak, J.
Journal Article
2001Transcriptional activation of liver enriched transcription factors and the albumin gene in rat hepatocytes by Aroclor 1254
Borlak, J.; Thum, T.
Journal Article
2001Untersuchungen zu möglichen kanzerogenen Effekten von Dämpfen und Aerosolen aus Bitumen nach inhalativer Aufnahme bei Ratten
Fuhst, R.; Levsen, K.; Koch, W.; Muhle, H.; Pohlmann, G.; Preiß, A.; Heinrich, U.
Journal Article
2001Verapamil metabolism in primary cultures of cardiomyocytes of adult rats and in distinct regions of explanted hearts
Thum, T.; Borlak, J.
Journal Article
2001Verapamil metabolism in rat heart tissue
Thum, T.; Walles, M.; Levsen, K.; Borlak, J.
Conference Paper, Journal Article
2000Inhalation tolerance study for p-Aramid respirable fiber-shaped particulates (RFP) in rats
Bellmann, B.; Creutzenberg, O.; Dasenbrock, C.; Ernst, H.; Pohlmann, G.; Muhle, H.
Journal Article
2000Investigation of chronic toxic and carcinogenic effects of gasoline engine exhausts deriving from fuel without and with ferrocene additive
Peters, L.; Ernst, H.; Koch, W.; Bartsch, W.; Bellmann, B.; Creutzenberg, O.; Hoymann, H.-G.; Dasenbrock, C.; Heinrich, U.
Journal Article
2000Local activation of nonspecific defense against a respiratory model infection by application of Interferon-gamma: Comparison between rat alveolar and interstitial lung macrophages
Steinmüller, C.; Franke-Ullmann, G.; Lohmann-Matthes, M.-L.; Emmendörffer, A.
Journal Article
2000Lung tumors in rats after repeated intratracheal instillation of coal dust
Rittinghausen, S.; Pott, F.; Roller, M.; Althoff, G.-H.; Ernst, H.; Mohr, U.
Conference Paper
2000Respiration
Schulz, H.; Muhle, H.
Book Article
199990-Tage-Inhalationstoxizitätsprüfung von Di-n-butylamin an Wistar(WU)-Ratten
Buschmann, J.; Dasenbrock, C.; Pohlmann, G.; Bartsch, W.; Creutzenberg, O.; Ernst, H.; Schneider, B.
Report
1999Chronic inhalation study in rats exposed to car exhaust originating from fuel with and without ferrocene additive
Peters, L.; Bartsch, W.; Bellmann, B.; Creutzenberg, O.; Dasenbrock, C.; Ernst, H.; Koch, W.; Heinrich, U.
Conference Paper
1999Effects of different cellulose-containing respirable samples in the lung of fischer 344 rats
Adamson, G.M.; Muhle, H.; Creutzenberg, O.; Bellmann, B.; Dasenbrock, C.
Journal Article
1999Spontaneous neoplastic lesions in Harlan Sprague-Dawley rats
Kaspareit, J.; Rittinghausen, S.
Journal Article
1998Cloning and chromosomal mapping of the human p53-related KET gene to chromosome 3q27 and its murine homolog Ket to mouse chromosome 16
Augustin, M.; Bamberger, C.; Paul, D.; Schmale, H.
Journal Article
1998Cystic squamous cell tumours in the lung of rats and Syrian hamsters induced by coal oven flue exhaust in combination with benzo(a)pyrene
Rittinghausen, S.; Dasenbrock, C.; Ernst, H.; Mohr, U.; Heinrich, U.
Conference Paper
1998The determination of trifluoroacetic acid in rat milk samples by 19F-NMR spectroscopy and capillary gas chromatography
Preiß, A.; Kruppa, J.; Buschmann, J.; Mügge, C.
Journal Article
1998Development of an in vitro system for studying effects of native and photochemically transformed gaseous compounds using an air/liquid culture technique
Knebel, J.W.; Ritter, D.; Aufderheide, M.
Journal Article
1998Effects of budesonide on airway hyperreactivity and inflammatory response in a rat model of allergic asthma
Hoymann, H.-G.; Hecht, M.; Emmendörffer, A.; Hohlfeld, J.; Bartsch, W.
Conference Paper
1998Einsatz immunologischer Methoden beim experimentell induzierten allergischem Asthma
Hecht, M.; Steinmüller, C.; Hoymann, H.-G.; Emmendörffer, A.
Conference Paper
1998Korrelation zwischen Lungenfunktion und zytologisch-biochemischen Parametern in einem Allergiemodell
Hoymann, H.-G.; Hecht, M.; Steinmüller, C.; Bartsch, W.; Ernst, H.
Conference Paper
1998Lung function changes in rats after chronic inhalation exposure to 4,4'-methylenediphenyldiisocyanate (MDI)
Hoymann, H.-G.; Creutzenberg, O.; Ernst, H.; Hohlfeld, J.; Heinrich, U.
Conference Paper
1998Measurement of lung function in rodents in vivo
Hoymann, H.-G.; Heinrich, U.
Book Article
1998Odontogenic fibroma in Sprague-Dawley rats: a report of 2 cases
Ernst, H.; Scampini, G.; Durchfeld-Meyer, B.; Brander-Weber, P.; Rittinghausen, S.
Journal Article
1998Pulmonary lesions in Wistar rats associated with chronic inhalation of 4,4'-methylene-diphenyl-diisocyanate (MDI)
Ernst, H.; Hoymann, H.-G.; Rittinghausen, S.; Mohr, U.; Heinrich, U.
Conference Paper
1998Spontaneous cystic keratinizing epithelioma in the lung of a Sprague-Dawley rat
Rittinghausen, S.; Kaspareit, J.
Journal Article
1998Spontaneous neoplasms of the nasal cavity in rats
Rittinghausen, S.; Kaspareit, J.; Ernst, H.
Journal Article
1998Use of primary rat and human hepatocyte sandwich cultures for activation of indirect carcinogens: Monitoring of DNA strand breaks and gene mutations in co-cultured cells
Fahrig, R.; Rupp, M.; Steinkamp-Zucht, A.; Bader, A.
Journal Article
1997Adenoma and adenocarcinoma of the nasal cavity in a Wistar rat
Rittinghausen, S.; Ernst, H.; Mohr, U.
Journal Article
1997Analysis of leukocyte activation during acute rejection of pulmonary allografts in noninfected and cytomegalovirus-infected rats
Steinmüller, C.; Steinhoff, G.; Bauer, D.; You, X.M.; Denzin, H.; Franke-Ullmann, G.; Hausen, B.; Brüggemann, C.; Wagner, T.O.F.; Lohmann-Matthes, M.-L.; Emmendörffer, A.
Journal Article
1997Biopersistance and bronchoalveolar lavage investigations in rats after a subacute inhalation of various man-made mineral fibres
Creutzenberg, O.; Bellmann, B.; Muhle, H.
Journal Article
1997Biopersistance of various types of mineral fibres in the rat lung after intratracheal application
Bellmann, B.; Muhle, H.
Conference Paper, Journal Article
1997Bioverfügbarkeit von feinstverteiltem metallischem Platin in der Lunge und erste orientierende Wirkungsuntersuchungen (VPT 09; 1. Teil)
Artelt, S.
Book Article
1997Bioverfügbarkeit von feinstverteiltem metallischem Platin in der Lunge und erste orientierende Wirkungsuntersuchungen (VPT 09; 2. Teil)
Emmendörffer, A.
Book Article
1997Chronic inhalation toxicity and carcinogenicity of 4,4-methylenediphenyldiisocyanate (MDI) in rats
Hoymann, H.-G.; Buschmann, J.; Ernst, H.; Bartsch, W.; Creutzenberg, O.; Bellmann, B.; Dasenbrock, C.; Koch, W.; Preiß, A.; Heinrich, U.
Journal Article
1997Dose-response relationship of fibrous dusts in intraperitoneal studies
Roller, M.; Pott, Friedrich; Kamino, Kenji; Althoff, G.-H.; Bellmann, Bernd
Journal Article, Conference Paper
1997International classification of rodent tumours. Part 1: The rat. 10. Digestive system
: Mohr, U.
Book
1997International classification of rodent tumours. Part 1: The rat. 8. Male genital system
: Mohr, U.
Book
1997International classification of rodent tumours. Part 1: The rat. 9. Female genital system
: Mohr, U.
Book
1997Investigation of the durability of cellulose fibres in rat lungs
Muhle, H.; Ernst, H.; Bellmann, B.
Journal Article
1997Investigations on health-related properties of two sepiolite samples
Bellmann, B.; Muhle, H.; Ernst, H.
Conference Paper
1997Significance of the biodurability of man-made vitreous fibres to risk assessment
Muhle, H.; Bellmann, B.
Conference Paper
1997The significance of toxicokinetics of solid particles in the rat lung
Muhle, H.
Book Article
1997Transforming growth factor-beta1 induces activation of Ras, Raf-1, MEK and MAPK in rat hepatic stellate cells
Reimann, T.; Hempel, U.; Krautwald, S.; Axmann, A.; Scheibe, R.; Seidel, D.; Wenzel, K.-W.
Journal Article
199632P-Postlabeling of a DNA adduct derived from 4,4'-methylenedianiline in the olfactory epithelium of rats exposed by inhalation to 4,4'methylenephenyl diisocyanate
Vock, E.H.; Hoymann, H.-G.; Heinrich, U.; Lutz, W.K.
Journal Article
1996Adenoma, carcinoma, parathyroid, rat
Kamino, K.; Ernst, H.; Kittel, B.
Book Article
1996Anatomy, histology, ultrastructure, parathyroid, rat
Kittel, B.; Kamino, K.; Ernst, H.
Book Article
1996The carcinogenic potency of carbon particles with and without PAH after repeated intratracheal administration in the rat
Dasenbrock, C.; Peters, L.; Creutzenberg, O.; Heinrich, U.
Journal Article
1996Comparative response to long-term particle exposure among rats, mice, and hamsters
Heinrich, U.
Journal Article
1996Craniopharyngeal derivatives in the neurohypophysis, rat and hamster
Karbe, E.; Ernst, H.
Book Article
1996Embryotoxicity study of monomeric 4,4'-Methylenediphenyl diisocyanate (MDI) aerosol after inhalation exposure in Wistar rats
Buschmann, J.; Koch, W.; Fuhst, R.; Heinrich, U.
Journal Article
1996Hyperplasia, parathyroid, rat
Kamino, K.; Kittel, B.; Ernst, H.
Book Article
1996Nonneoplastic lesions in the lungs
Dungworth, D.L.; Ernst, H.; Mohr, U.; Nolte, T.; Kamino, K.; Rittinghausen, S.
Book Article
1996Requirement of monooxygenase induction in cultured lung epithelial cells for metabolism of PAH
Jacob, J.; Emura, M.; Grimmer, G.; Knebel, J.W.; Raab, G.; Mohr, U.
Journal Article
1996Results of current intraperitoneal carcinogenicity studies with mineral and vitreous fibres
Roller, M.; Pott, F.; Kamino, K.; Althoff, G.-H.; Bellmann, B.
Journal Article
1996Squamous metaplasia, lung, rat
Nolte, T.; Ernst, H.; Dungworth, D.L.
Book Article
1995Ameloblastoma in a female Wistar rat
Ernst, H.; Mirea, D.
Journal Article
1995Biobeständigkeit verschiedener Mineralfasertypen in der Rattenlunge nach intratrachealer Applikation
Bellmann, B.; Muhle, H.
Book
1995Bronchoalveolar lavage analysis following a subacute inhalation of various man-made mineral fibres in rats
Creutzenberg, O.; Bellmann, B.; Muhle, H.
Journal Article
1995Chronic inhalation exposure of Wistar rats and two different strains of mice to diesel engine exhaust, carbon black, and titanium dioxide
Heinrich, U.; Fuhst, R.; Rittinghausen, S.; Creutzenberg, O.; Bellmann, B.; Koch, W.; Levsen, K.
Journal Article
1995A congenital basal cell carcinoma in a weaning rat
Kuroda, J.; Yoshimura, H.; Ernst, H.
Journal Article
1995Granulomatous dermatitis and mastitis in two SPF rats associated with a slowly growing Staphylococcus aureus - a case report
Kunstyr, I.; Ernst, H.; Lenz, W.
Journal Article
1995Hemoglobin adducts and urine metabolites of 4,4'-methylenedianiline after 4,4'-methylenediphenyl diisocyanate exposure of rats
Sepai, O.; Schütze, D.; Heinrich, U.; Hoymann, H.-G.; Henschler, D.; Sabbioni, G.
Journal Article
1995Neoplastic lung lesions in rat after chronic exposure to crystalline silica
Muhle, H.; Kittel, B.; Ernst, H.; Mohr, U.; Mermelstein, R.
Journal Article
1995Phagocytosis and chemotaxis of rat alveolar macrophages after a combined or separate exposure to ozone and carbon black
Creutzenberg, O.; Bellmann, B.; Klingebiel, R.; Heinrich, U.; Muhle, H.
Conference Paper
1995RITA - registry of industrial toxicology animal-data (1995). Guides for organ sampling and trimming procedures in rats
Bahnemann, R.; Jacobs, M.; Karbe, E.; Kaufmann, W.; Morawietz, G.; Nolte, T.; Rittinghausen, S.
Journal Article
1995Untersuchungen zur chronischen Toxizität/Kanzerogenität von 4,4'-Methylendiphenyl-Diisocyanat (MDI). Bd.1
Hoymann, Heinz-Gerd; Buschmann, Jochen; Heinrich, Uwe
Report
1994Aerosolized surfactant inhibits acetylcholine-induced bronchoconstruction in rats
Hohlfeld, J.; Molthan, J.; Hoymann, H.-G.; Fabel, H.; Heinrich, U.
Conference Paper
1994Bronchoconstriction induced by aerosolized acetylcholine but not by acetylcholine given intravenously is inhibited by aerosolized surfactant in rats
Hohlfeld, J.; Molthan, J.; Hoymann, H.-G.; Fabel, H.; Heinrich, U.
Conference Paper
1994The carcinogenic effects of carbon black particles and tar-pitch condensation aerosol after inhalation exposure of rats
Heinrich, U.; Dungworth, D.L.; Pott, F.; Peters, L.; Dasenbrock, C.; Levsen, K.; Koch, W.; Creutzenberg, O.; Schulte, A.
Journal Article
1994Carcinogenic effects of solid particles
Heinrich, U.
Conference Paper
1994Comparative investigation of the effects of zardaverine and theophylline on pulmonary function in rats
Hoymann, H.-G.; Heinrich, U.; Beume, R.; Kilian, U.
Journal Article
1994Comparative investigations of the biodurability of mineral fibers in the rat lung
Muhle, H.; Bellmann, B.; Pott, F.
Conference Paper
1994Effects of single and combined, subchronic exposure to ozone and soot particles on pulmonary surfactant phospholipids and associated protein A and on surface activity in rat lung lavage fluid
Klingebiel, R.; Heinrich, U.; Martin-Carrera, I.; Dettmer, M.; Kühn, A.; Bartsch, W.
Conference Paper
1994Der Effekt von inhaliertem Terbutalin auf die Acetylcholin-induzierte Bronchokonstriktion wird durch vernebeltes Surfactant nicht verstärkt
Hohlfeld, J.; Molthan, J.; Hoymann, H.-G.; Fabel, H.; Heinrich, U.
Conference Paper
1994Estimation of a lifetime unit lung cancer risk for benzo(a)pyrene (BaP) based on tumor rates in rats exposed to coal tar/pitch condensation aerosol -CTP-
Heinrich, U.; Pott, F.; Roller, M.
Conference Paper, Journal Article
1994Estimation of a lifetime unit lung cancer risk for benzo/a/pyrene based on tumour rates in rats exposed to coal tar/pitch condensation aerosol
Heinrich, U.; Roller, M.; Pott, F.
Journal Article
1994Formation of DNA adducts in rat lung following chronic inhalation of diesel emissions, carbon black and titanium dioxide particles
Gallagher, J.; Heinrich, U.; George, M.; Hendee, L.; Phillips, D.H.; Lewtas, J.
Journal Article
1994Goblet cell metaplasia in the peripheral lung tissue of rats after chronic exposure to particles
Kittel, B.; Dungworth, D.L.; Mohr, U.
Conference Paper
1994Histological and ultrastructural alterations of the bronchioloalveolar region in the rat lung after chronic exposure to a pyrolized pitch condensate of carbon black, alone or in combination
Nolte, T.; Thiedemann, K.-U.; Dungworth, D.L.; Ernst, H.; Paulini, I.; Heinrich, U.; Dasenbrock, C.; Peters, L.; Ueberschär, S.; Mohr, U.
Journal Article
1994Inhalation exposure of rats to tar/pitch condensation aerosol or carbon black alone or in combination with irritant gases
Heinrich, U.; Peters, L.; Creutzenberg, O.; Dasenbrock, C.; Hoymann, H.-G.
Conference Paper
1994International classification of rodent tumours. Part 1: The rat. 6. Endocrine system
: Mohr, U.
Book
1994International classification of rodent tumours. Part 1: The rat. 7. Central nervous system, heart, eye, mesothelium
: Mohr, U.
Book
1994Investigation of the biodurability and carcinogenicity of different man-made mineral fibres
Bellmann, B.; Muhle, H.; Pott, F.
Conference Paper
1994Investigation of the biodurability of wollastonite and xonotlite
Bellmann, B.; Muhle, H.
Conference Paper
1994Investigation on the durability of man-made vitreous fibers in rat lungs
Bellmann, B.; Muhle, H.; Kamstrup, O.; Draeger, U.F.
Conference Paper
1994Investigation on the durability of man-made vitreous fibres in rat lungs. Final report
: Bellmann, B.
Report
1994Lung tumours in rats after intratracheal instillation of dusts
Pott, F.; Dungworth, D.L.; Heinrich, U.; Muhle, H.; Kamino, K.; Germann, P.-G.; Roller, M.; Rippe, R.M.; Mohr, U.
Conference Paper
1994Nasal retention and clearance of wood dust in rats
Creutzenberg, O.; Muhle, H.; Bellmann, B.
Journal Article
1994Pathologic effects of inhaled particles in rat lungs - Associations between inflammatory and neoplastic processes
Dungworth, D.L.; Mohr, U.; Heinrich, U.; Ernst, H.; Kittel, B.
Conference Paper
1994Phagocytosis and chemotaxis of rat alveolar macrophages after a combined or separate exposure to ozone and carbon black
Creutzenberg, O.; Bellmann, B.; Klingebiel, R.; Heinrich, U.; Muhle, H.
Conference Paper
1994Significance of biodurability of mineral fibers for their toxicity and carcinogenic potency in the abdominal cavity of rats in comparison with the low sensitivity of inhalation studies
Pott, F.; Roller, M.; Kamino, K.; Bellmann, B.
Journal Article
1994Toxicokinetics of solid particles in chronic studies using diesel soot, carbon black, toner, titanium dioxide and quartz
Muhle, H.; Bellmann, B.; Creutzenberg, O.
Conference Paper
1994Type A natriuretic peptides exhibit different bronchoprotective effects in rats
Flüge, T.; Hoymann, H.-G.; Hohlfeld, J.; Heinrich, U.; Fabel, H.; Wagner, T.O.; Forssmann, W.-G.
Journal Article
1994Untersuchungen zur Biobeständigkeit von Wollastonitfasern.
Bellmann, B.; Muhle, H.
Journal Article
1993Additional atypical malignant mesothelioma after intraperitoneal injection of mineral fibres in rats. Letter to the editor
Kamino, K.; Ernst, H.; Mohr, U.
Journal Article
1993Carcinogenic effects of solid particles
Heinrich, U.
Conference Paper
1993Development of short-term mutagenicity test systems in vitro - metabolic activation of indirectly acting mutagens by three immortal rat hepatocyte lines
Kulka, U.; Paul, D.; Bauchinger, M.
Journal Article
1993Differences in the phenanthrene metabolism of tumor-free and tumor-bearing rats
Grimmer, G.; Heinrich, U.; Jacob, J.; Dettbarn, G.; Naujack, K.-W.
Conference Paper
1993Effects of single and combined, subchronic exposure to ozone and soot particles on pulmonary surfactant phospholipids, associated protein A and on surface activity in rat lung lavage fluid
Klingebiel, R.; Heinrich, U.; Martin-Carrera, I.; Dettmer, M.; Kühn, A.; Bartsch, W.; Hoymann, H.-G.
Conference Paper
1993Effects of single and combined, subchronic exposure to ozone and soot particles on the pulmonary surfactant system and on biochemical and cellular markers of inflammation in the rat lung
Klingebiel, R.; Creutzenberg, O.; Bartsch, W.; Ernst, H.; Heinrich, U.; Muhle, H.
Journal Article
1993Goblet cell metaplasia in rat lungs after chronic exposure to particles
Kittel, B.; Dungworth, D.L.; Mohr, U.
Conference Paper
1993International classification of rodent tumours. Part 1: The rat. 4. Haematopoietic system
: Mohr, U.
Book
1993International classification of rodent tumours. Part 1: The rat. 5. Integumentary system
: Mohr, U.
Book
1993Investigation on the biodurability of chemically different stone wool fibres
Bellmann, B.; Muhle, H.; Kamstrup, O.; Draeger, U.F.
Conference Paper
1993Investigation on the biodurability of different man-made mineral fibres
Bellmann, B.; Muhle, H.
Conference Paper
1993Long-term inhalation exposure of rats and mice to diesel exhaust (DE), carbon black (CB), and titanium dioxide (TiO2)
Heinrich, U.; Fuhst, R.; Dasenbrock, C.; Muhle, H.; Koch, W.; Mohr, U.
Conference Paper
1993Mammary adenolipoma in a female Sprague-Dawley rat. Short communication
Germann, P.-G.; Ernst, H.
Journal Article
1993Morphological comparison between benign keratinizing cystic squameous cell tumours of the lung and squameous lesions of the skin in rats
Kittel, B.; Ernst, H.; Dungworth, D.L.; Rittinghausen, S.; Nolte, T.; Kamino, K.; Stuart, B.P.; Lake, S.G.; Cardesa, A.; Morawietz, G.; Mohr, U.
Journal Article
1993Morphology and histogenesis of squamous cell metaplasia of the rat lung after chronic exposure to a pyrolized pitch condensate and/or carbon black, or to combinations of pyrolized pitch condensate, carbon black and irritant gases
Nolte, T.; Thiedemann, K.-U.; Dungworth, D.L.; Ernst, H.; Paulini, I.; Heinrich, U.; Dasenbrock, C.; Peters, L.; Ueberschär, S.; Mohr, U.
Journal Article
1993Pathologic effects of inhaled particles in rat lungs - Associations between inflammatory and neoplastic processes
Dungworth, D.L.; Mohr, U.; Heinrich, U.; Ernst, H.; Kittel, B.
Conference Paper
1993Phagocytosis and chemotaxis of rat alveolar macrophages after a combined or separate exposure to ozone and carbon black
Creutzenberg, O.; Bellmann, B.; Klingebiel, R.; Heinrich, U.; Muhle, H.
Conference Paper
1993Regeneration, differentiation, and neoplastic transformation of type II alveolar epithelial cells
Thiedemann, K.-U.; Paulini, I.; Lüthe, N.; Kreft, A.; Abel, U.; Glaser, U.; Mohr, U.
Conference Paper
1993Toxicokinetics of solid particles in chronic studies - An overview
Muhle, H.
Conference Paper
1992Adenolipome der Mamma bei Sprague-Dawley und Wistar-Ratten
Germann, P.-G.; Nolte, T.; Ernst, H.; Tuch, K.
Conference Paper
1992Atypical malignant mesotheliomas with osseous and cartilaginous differentiation after intraperitoneal injection of various types of mineral fibres in rats
Ernst, H.; Mohr, U.; Muhle, H.; Rittinghausen, S.
Journal Article
1992Effect of photocorrosion on cadmium sulfide suspensions applied in animal inhalation studies with CdS particles
Heinrich, U.; Kock, H.; König, H.P.; Peters, L.
Journal Article
1992Effects of single and combined, subchronic exposure to ozone and soot particles on the pulmonary surfactant system and lung mechanics in rats
Klingebiel, R.; Heinrich, U.; Dettmer, M.; Martin-Carrera, I.; Hoymann, H.-G.; Kühne, A.; Bartsch, W.
Conference Paper
1992International classification of rodent tumours. Part 1: The rat. 1. Respiratory system
: Mohr, U.
Book
1992International classification of rodent tumours. Part 1: The rat. 2. Soft tissue and musculoskeletal system
: Mohr, U.
Book
1992International classification of rodent tumours. Part 1: The rat. 3. Urinary system
: Mohr, U.
Book
1992Irreversible pulmonary changes induced in rat lung by dust overload
Bellmann, B.; Creutzenberg, O.; Mermelstein, R.; Muhle, H.
Conference Paper
1992Nonneoplastic lesions in the lungs
Dungworth, D.L.; Ernst, H.; Mohr, U.; Nolte, T.; Kamino, K.; Rittinghausen, S.
Book Article
1992On the influence of different housing conditions and a sham inhalation exposure of rats on teratological endpoints
Buschmann, J.
Journal Article
1992Osteochondroma in laboratory rats. A report of 3 casesin a Fischer-344, a Sprague Dawley, and a Wistar rat. Brief communication
Ernst, H.; Karbe, E.; Mohr, U.; Nolte, T.; Sander, E.
Journal Article
1992Potassium channel activation improves blood flow pattern of conscious rats in cutaneous microcirculation
Hertel, R.F.
Journal Article
1992Protective effect of urodilatin (URO) or ANP against an acetylcholine(ACH)-induced bronchoconstriction in the rat in vivo
Flüge, T.; Hoymann, H.-G.; Hohlfeld, J.; Heinrich, U.; Fabel, H.; Wagner, T.O.F.
Conference Paper, Journal Article
1992Pulmonary carcinogenicity of cadmium by inhalation in animals
Heinrich, U.
Conference Paper
1992RITA - Registry of Industrial Toxicology Animal data. Progress of the working group
Mohr, U.; Morawietz, G.; Rittinghausen, S.
Journal Article
1992Tierexperimentelle Inhalationsstudien zur Frage der tumorinduzierenden Wirkung von Dieselmotorabgasen und zwei Teststäuben
Heinrich, U.; Fuhst, R.; Mohr, U.
Book Article
1992Variations in prevalence of endocrine tumors among different colonies of rats? A retrospective study in the Hannover registry data base
Morawietz, G.; Rittinghausen, S.
Conference Paper
1991Ameloblastic odontoma of the mandible, rat
Ernst, H.; Mohr, U.
Book Article
1991Bronchoprotective effect of zardaverine versus theophylline in rats
Hoymann, H.G.; Beume, R.; Kilian, U.; Heinrich, U.
Conference Paper
1991Comparison of the effects of zardaverine and theophylline on pulmonary function in rats.
Hoymann, H.G.; Heinrich, U.; Beume, R.; Kilian, U.
Conference Paper
1991Comparison of the protective effect of intravenous urodilatin (URO) or ANP against an acetylcholine(ACh)-induced bronchoconstriction in the rat in vivo
Flüge, T.; Hoymann, H.-G.; Hohlfeld, J.; Heinrich, U.; Fabel, H.; Wagner, T.O.F.
Journal Article
1991Effects of 12 weeks exposure to a diisocyanate -MDI- on the pulmonary surfactant system and bronchoalveolar cell content in rats
Klingebiel, R.; Creutzenberg, O.; Hoymann, H.-G.; Dettmer, M.; Schüler, T.; Heinrich, U.
Conference Paper
1991Effects of subchronic exposure to a diisocyanate -MDI- on the pulmonary surfactant system and lung function.
Martin-Carrera, I.; Klingebiel, R.; Hoymann, H.G.; Heinrich, U.
Conference Paper
1991Effects of the tumor promoter 2,3,7,8-tetrachlorodibenzo-p-dioxin -TCDD- on the regulation of growth and inositolphosphate formation in primary rat hepatocytes
Wölfle, D.; Schmutte, C.; Marquardt, H.
Conference Paper
1991Formation of DNA adducts by the hydroxyanthraquinone lucidin
Poginsky, B.; Phillips, D.H.; Westendorf, J.; Marquardt, H.; Blömeke, B.
Conference Paper
1991Histopathological analysis of tumour types after intraperitoneal injection of mineral fibers in rats
Rittinghausen, S.; Ernst, H.; Muhle, H.; Fuhst, R.; Mohr, U.
Conference Paper
1991Histopathological analysis of tumour types after intraperitoneal injection of mineral fibers in rats
Rittinghausen, S.; Ernst, H.; Muhle, H.; Fuhst, R.; Mohr, U.
Conference Paper