Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2018An immune cell spray (ICS) formulation allows for the delivery of functional monocyte/macrophages
Beneke, Valerie; Küster, Fennja; Neehus, Anna-Lena; Hesse, Christina; Lopez-Rodriguez, Elena; Haake, Kathrin; Rafiei Hashtchin, Anna; Schott, Juliane Wilhelmine; Walter, Dorothee; Braun, Armin; Wolkers, Willem F.; Ackermann, Mania; Lachmann, Nico
Journal Article
2018Investigation into pulmonary absorption using a combination of the ex vivo model of isolated perfused rat lungs and a simple PK model
Schwarz, Katharina; Koch, Wolfgang; Walter, Dorothee
Abstract
2016Biokinetic datasets of PEI F25-LMW complexed and non-complexed 32P-siRNA within different lung compartments
Lipka, Jens; Semmler-Behnke, Manuela; Wenk, Alexander; Burkhardt, Jana; Aigner, Achim; Kreyling, Wolfgang
Journal Article
2015Evaluation of the fate and pathological response in the lung and pleura of brake dust alone and in combination with added chrysotile compared to crocidolite asbestos following short-term inhalation exposure
Bernstein, David M.; Rogers, R.A.; Sepulveda, Rosalina; Kunzendorf, Peter; Bellmann, Bernd; Ernst, Heinrich; Creutzenberg, Otto H.; Phillips, James I.
Journal Article
2013Zur Entstehung, Charakterisierung und diagnostischen Nutzbarkeit in der menschlichen Lunge endogen generierter exhalierter Aerosole
Schwarz, Katharina
: Turek, Thomas (Vorsitzender); Koch, Wolfgang (Erstprüfer); Weber, Alfred (Zweitprüfer)
Dissertation
2012Etablierung pathway-spezifischer Genexpressionsanalysen am Beispiel der Wirkung von Paraquat auf humane Lungenepithelzellen
Augustin, Christian
: Pfitzner, Reinhard (Erstprüfer); Niehof, Monika (Zweitprüfer)
Bachelor Thesis
2012Lung tumour growth kinetics in SPC-c-Raf-1-BB transgenic mice assessed by longitudinal in-vivo micro-CT quantification
Rodt, Thomas; Falck, Christian von; Dettmer, Sabine; Hueper, Katja; Halter, Roman; Hoy, Ludwig; Luepke, Matthias; Borlak, Jürgen; Wacker, Frank
Journal Article
2012Marmoset monkeys as a preclinical model in respiratory research
Seehase, Sophie
: Kaup, Franz-Josef (1. Gutachter); Zimmermann, Elke (2. Gutachterin); Braun, Armin (Wiss. Betreuung)
Dissertation
2012A pilot study on the refinement of acute inhalation toxicity studies
Fischer, M.; Koch, W.; Windt, H.; Dasenbrock, C.
Journal Article
2012The respiratory tract
Braun, Armin; Ernst, Heinrich; Schaudien, Dirk; Hoymann, Heinz-Gerd; Rittinghausen, Susanne
Book Article
2011CD4(+)CD25(+)Foxp3(+) regulatory T cells are dispensable for controlling CD8(+) T cell-mediatedl lung inflammation
Tosiek, Milena J.; Gruber, Achim D.; Bader, Sophie R.; Mauel, Susanne; Hoymann, Heinz-Gerd; Prettin, Silvia; Tschernig, Thomas; Buer, Jan; Gereke, Marcus; Bruder, Dunja
Journal Article
2011Histologische und elektronenmikroskopische Untersuchungen der Lunge nach Inhalation von Titandioxid-Nanopartikeln bzw. -Feinpartikeln bei der Ratte
Eydner, M.
: Baumgärtner, W.; Pfarrer, C.
Dissertation
2010Assessment of pulmonary function and serum substance levels in newborn and juvenile rats
Lewin, G.; Hoymann, H.-G.; Fuhst, R.; Berger-Preiß, E.; Pohlmann, G.; Buschmann, J.
Journal Article
2010Cell isolation from lung tumour tissue
Appelt, A.; Jany, C.; Heymer, A.
Journal Article
2009The Second International Workshop on Pulmonary Image Analysis 2009
: Brown, M.; Bruijne, M.; Ginneken, B.V.; Kiraly, A.; Kuhnigk, J.-M.; Lorenz, C.; McClelland, J.; Mori, K.; Reeves, A.; Reinhardt, J.
Conference Proceedings
2008In vitro and in vivo screening of the cytotoxic, pro-inflammatory and genotoxic potential of quartz-containing ceramic dusts
Ziemann, C.; Hansen, T.; Ernst, H.; Jackson, P.; Brown, R.; Creutzenberg, O.
Journal Article, Conference Paper
2008Keratinocyte growth factor prevents intra-alveolar oedema in experimental lung isografts
Sadovski, J.; Kuchenbuch, T.; Ruppert, C.; Fehrenbach, A.; Hirschburger, M.; Padberg, W.; Günther, A.; Hohlfeld, J.M.; Fehrenbach, H.; Grau, V.
Journal Article
2008Quantitative analysis of lung morphology and function in computed tomographic images
Kuhnigk, J.-M.
Dissertation
200724 months inhalation carcinogenicity study of bitumen fumes in Wistar (WU) rats
Fuhst, R.; Creutzenberg, O.; Ernst, H.; Hansen, T.; Pohlmann, G.; Preiss, A.; Rittinghausen, S.
Journal Article
2007Interobserver-variability of lung nodule volumetry considering different segmentation algorithms and observer training levels
Bolte, H.; Jahnke, T.; Schäfer, F.K.W.; Wenke, R.; Hoffmann, B.; Freitag-Wolf, S.; Dicken, V.; Kuhnigk, J.-M.; Lohmann, J.; Voß, S.; Knöß, N.; Heller, M.; Biederer, J.
Journal Article
2007Invasive and noninvasive methods for studying pulmonary function in mice
Glaab, T.; Taube, C.; Braun, A.; Mitzner, W.
Journal Article
2006CT-basierte softwaregestützte Vorhersage der postoperativen Lungenfunktion nach Lungenteilresektion
Beyer, F.; Heindel, W.; Hoffknecht, P.; Kuhnigk, J.-M.; Dicken, V.; Lange, T.; Thomas, M.; Wormanns, D.
Journal Article
2006Etablierung der bodyplethysmographischen Messung der Lungenfunktion im Asthmamodell der Maus
Ziegert, M.
Dissertation
2006The kinetics of transcriptomic changes induced by cigarette smoke in rat lungs reveals a specific program of defense, inflammation, and circadian clock gene expression
Gebel, S.; Gerstmayer, B.; Kuhl, P.; Borlak, J.; Meurrens, K.; Müller, T.
Journal Article
2006Morphological segmentation and partial volume analysis for volumetry of solid pulmonary lesions in thoracic CT scans
Kuhnigk, J.-M.; Dicken, V.; Bornemann, L.; Bakai, A.; Wormanns, D.; Krass, S.; Peitgen, H.-O.
Journal Article
2006Onkoproteomics von Lungentumoren
Chatterji, B.; Ritorto, M.S.; Garaguso, I.; Belau, E.; Gazzana, G.; Borlak, J.
Journal Article
2006Quantifizierung des Lungenemphysems in der Mehrschicht-CT mittels verschiedener Softwareverfahren
Heußel, C.P.; Achenbach, T.; Buschsieweke, C.; Kuhnigk, J.; Weinheimer, O.; Hammer, G.; Düber, C.; Kauczor, H.U.
Journal Article
2005Pathogenetische und immunbiologische Untersuchungen zur Frage: Ist die Extrapolation der Staubkanzerogenität von der Ratte auf den Menschen gerechtfertigt? Teil II: Histologie
Ernst, H.; Kolling, A.; Bellmann, B.; Rittinghausen, S.; Heinrich, U.; Pott, F.
Report
2004An "omics" approach to study lung carcinogenesis
Borlak, J.; Meier, T.; Rütters, H.; Zürbig, P.; Halter, R.
Conference Paper
2004Respirationstrakt
Muhle, H.; McClellan, R.O.
Book Article
2003Exposure of human lung cells to inhalable substances
Ritter, D.; Knebel, J.W.; Aufderheide, M.
Journal Article
2003In-situ topical cooling of lung grafts
Kutschka, I.; Sommer, S.P.; Hohlfeld, J.M.; Warnecke, G.; Morancho, M.; Fischer, S.; Haverich, A.; Strüber, M.
Journal Article
2003Increase of inactive intra-alveolar surfactant subtypes in lungs of asthmatic Brown Norway rats
Schmiedl, A.; Hoymann, H.-G.; Ochs, M.; Menke, A.; Fehrenbach, A.; Krug, N.; Tschernig, T.; Hohlfeld, J.M.
Journal Article
2002Crucial issues in inhalation research - mechanistic, clinical and epidemiologic
: Heinrich, U.; Mohr, U.
Conference Proceedings
2002Pulmonary inflammation in rats after intratracheal instillation of quartz, amorphous SiO2, carbon black, and coal dust and the influence of poly-2-vinylpyridine-N-oxide (PVNO)
Ernst, H.; Rittinghausen, S.; Bartsch, W.; Creutzenberg, O.; Dasenbrock, C.; Görlitz, B.-D.; Hecht, M.; Kairies, U.; Muhle, H.; Müller, M.; Heinrich, U.; Pott, F.
Journal Article
2002Surfactant function in lung transplantation after 24 hours of ischemia
Strüber, M.; Hohlfeld, J.M.; Kofidis, T.; Warnecke, G.; Niedermeyer, J.; Sommer, S.P.; Haverich, A.
Journal Article
2001Chronic pulmonary effects of respirable methylene diphenyl diisocyanate (MDI) aerosol in rats
Feron, V.J.; Kittel, B.; Kuper, C.F.; Ernst, H.; Rittinghausen, S.; Muhle, H.; Koch, W.; Gamer, A.; Mallett, A.K.; Hoffmann, H.D.
Journal Article
2001Development of pulmonary bronchiolo-alveolar adenocarcinomas in transgenic mice overexpressing murine c-myc and epidermal growth factor in alveolar type II pneumocytes
Ehrhardt, A.; Bartels, T.; Geick, A.; Klocke, R.; Paul, D.; Halter, R.
Journal Article
2001A simple pulmonary retention model accounting for dissolution and macrophage-mediated removal of deposited polydisperse particles
Koch, W.; Stöber, W.
Journal Article
2001Steroid metabolism in co-cultures of A/J mouse alveolar epithelial type II cells and Clara cells
Hansen, T.; Borlak, J.
Conference Paper, Journal Article
2001Testverfahren für inhalative Testung auf allergenes Potenzial
Hoymann, H.G.; Krug, N.
Journal Article
2000Aspiration und "near drowning"
Hohlfeld, J.M.; Fabel, H.
Journal Article
2000CULTEX. An alternative technique for cultivation and exposure of cells of the respiratory tract to airborne pollutants at the air/liquid interface
Aufderheide, M.; Mohr, U.
Journal Article
2000Inhalation tolerance study for p-Aramid respirable fiber-shaped particulates (RFP) in rats
Bellmann, B.; Creutzenberg, O.; Dasenbrock, C.; Ernst, H.; Pohlmann, G.; Muhle, H.
Journal Article
2000Phospholipid molecular species of bronchoalveolar lavage fluid after local allergen challenge in asthma
Heeley, E.L.; Hohlfeld, J.M.; Krug, N.; Postle, A.D.
Journal Article
2000Stellenwert des intensivmedizinischen Monitoring mit dem Pulmonararterienkatheter
Hohlfeld, J.M.; Niedermeyer, J.; Fabel, H.
Journal Article
1999Allergie der Lunge und ihre pharmakologische Beeinflussung. Workshop
 
Conference Proceedings
1999Chronic inhalation study in rats exposed to car exhaust originating from fuel with and without ferrocene additive
Peters, L.; Bartsch, W.; Bellmann, B.; Creutzenberg, O.; Dasenbrock, C.; Ernst, H.; Koch, W.; Heinrich, U.
Conference Paper
1999Freisetzung feiner und lungengängiger Stäube durch kurzzeitige Einwirkung mechanischer Kräfte
Mädler, L.
: Koch, W. (Prüfer)
Dissertation
1998Abschlußbericht zur Studie "Persistenzuntersuchungen von Mineralfasern in vivo und in vitro und Entwicklung von Beurteilungskriterien für die Biobeständigkeit"
Muhle, H.; Sebastian, K.; Bellmann, B.; Böhm, T.
Book Article
1998Endobronchial allergen challenge
Frew, A.J.; Carroll, M.P.; Gratziou, C.; Krug, N.
Journal Article
1998Etablierung transgener Mausmodelle für humane Lungenkarzinome
Ehrhardt, A.
Dissertation
1998Lung clearance and retention of toner, TiO2, and crystalline silica, utilizing a tracer technique during chronic inhalation exposure in syrian golden hamsters
Creutzenberg, O.; Bellmann, B.; Muhle, H.; Dasenbrock, C.
Journal Article
1998Lung function changes in rats after chronic inhalation exposure to 4,4'-methylenediphenyldiisocyanate (MDI)
Hoymann, H.-G.; Creutzenberg, O.; Ernst, H.; Hohlfeld, J.; Heinrich, U.
Conference Paper
1998Measurement of lung function in rodents in vivo
Hoymann, H.-G.; Heinrich, U.
Book Article
1998Pulmonary response to toner, TiO2 and crystalline silica upon chronic inhalation exposure in syrian golden hamsters
Muhle, H.; Bellmann, B.; Creutzenberg, O.; Koch, W.; Dasenbrock, C.; Ernst, H.; Mohr, H.
Journal Article
1998Spontaneous cystic keratinizing epithelioma in the lung of a Sprague-Dawley rat
Rittinghausen, S.; Kaspareit, J.
Journal Article
1998Transgene Mausmodelle zur Analyse der Aktivität des Uteroglobin-Promotors und der Entstehung von Clara-Zell-Karzinomen, renalen Tumoren und lymphoblastischen Lymphomen
Geick, A.
Dissertation
1997Aerosolized surfactant inhibits acetylcholine-induced airway obstruction in rats
Hohlfeld, J.; Hoymann, H.-G.; Molthan, J.; Fabel, H.; Heinrich, U.
Journal Article
1997Biopersistance and bronchoalveolar lavage investigations in rats after a subacute inhalation of various man-made mineral fibres
Creutzenberg, O.; Bellmann, B.; Muhle, H.
Journal Article
1997Biopersistance of various types of mineral fibres in the rat lung after intratracheal application
Bellmann, B.; Muhle, H.
Conference Paper, Journal Article
1997Bioverfügbarkeit von feinstverteiltem metallischem Platin in der Lunge und erste orientierende Wirkungsuntersuchungen (VPT 09; 1. Teil)
Artelt, S.
Book Article
1997Bioverfügbarkeit von feinstverteiltem metallischem Platin in der Lunge und erste orientierende Wirkungsuntersuchungen (VPT 09; 2. Teil)
Emmendörffer, A.
Book Article
1997Cystic keratinizing squamous cell carcinomas in the lung of Syrian hamsters induced by coal oven flue exhaust mixed with pyrolized tar pitch in combination with benzo(a)pyrene
Rittinghausen, S.; Dasenbrock, C.; Mohr, U.
Journal Article
1997Cystic squamous cell carcinomas in the lungs of Syrian golden hamsters induced by coal oven flue exhaust mixed with pyrolized tar pitch in combination with benzo(a)pyrene
Rittinghausen, S.; Dungworth, D.L.; Dasenbrock, C.; Ernst, H.; Mohr, U.
Journal Article
1997Erhöhtes Tumorrisiko nach paternaler Exposition gegenüber Röntgenstrahlen oder Urethan bei CBA/J-Nchkommen?
Dasenbrock, C.; Mohr, U.
Conference Paper
1997Investigation of the durability of cellulose fibres in rat lungs
Muhle, H.; Ernst, H.; Bellmann, B.
Journal Article
1997Investigations on health-related properties of two sepiolite samples
Bellmann, B.; Muhle, H.; Ernst, H.
Conference Paper
1997Persistenzuntersuchungen von Mineralfasern in vivo und in vitro und Entwicklung von Beurteilungskriterien für die Biobeständigkeit
Bellmann, B.; Böhm, T.; Muhle, H.; Sebastian, K.
Report
1997Significance of the biodurability of man-made vitreous fibres to risk assessment
Muhle, H.; Bellmann, B.
Conference Paper
1997The significance of toxicokinetics of solid particles in the rat lung
Muhle, H.
Book Article
199632P-Postlabeling of a DNA adduct derived from 4,4'-methylenedianiline in the olfactory epithelium of rats exposed by inhalation to 4,4'methylenephenyl diisocyanate
Vock, E.H.; Hoymann, H.-G.; Heinrich, U.; Lutz, W.K.
Journal Article
1996Biobeständigkeit anorganischer und organischer Fasern
Muhle, H.
Journal Article
1996The carcinogenic potency of carbon particles with and without PAH after repeated intratracheal administration in the rat
Dasenbrock, C.; Peters, L.; Creutzenberg, O.; Heinrich, U.
Journal Article
1996Characterization of murine lung interstitial macrophages in comparison with alveolar macrophages in vitro
Franke-Ullmann, G.; Pförtner, C.; Walter, P.; Steinmüller, C.; Lohmann-Matthes, M.-L.; Kobzik, L.
Journal Article
1996Comparative response to long-term particle exposure among rats, mice, and hamsters
Heinrich, U.
Journal Article
1996Cystic keratinizing squamous cell carcinomas in the lung of Syrian hamsters induced by a coal oven flue exhaust mixed with pyrolized tar pitch in combination with benzo(a)pyrene
Rittinghausen, S.; Dasenbrock, C.; Mohr, U.
Book Article
1996Embryotoxicity study of monomeric 4,4'-Methylenediphenyl diisocyanate (MDI) aerosol after inhalation exposure in Wistar rats
Buschmann, J.; Koch, W.; Fuhst, R.; Heinrich, U.
Journal Article
1996Naturally-occurring pulmonary tumors in rodents
Rittinghausen, S.; Dungworth, D.L.; Ernst, H.; Mohr, U.
Book Article
1996Nonneoplastic lesions in the lungs
Dungworth, D.L.; Ernst, H.; Mohr, U.; Nolte, T.; Kamino, K.; Rittinghausen, S.
Book Article
1996PAH metabolism in cultured mammalian lung epithelial cells
Emura, M.; Jacob, J.; Grimmer, G.; Knebel, J.W.; Raab, G.; Mohr, U.
Journal Article
1996Pulmonary surfactant impairment in lung transplant recipients
Hohlfeld, J.M.; Tiryaki, E.; Hamm, H.; Tschorn, H.; Schöfers, H.J.; Hoymann, H.G.; Wagner, T.O. F.; Fabel, H.
Conference Paper, Journal Article
1996Requirement of monooxygenase induction in cultured lung epithelial cells for metabolism of PAH
Jacob, J.; Emura, M.; Grimmer, G.; Knebel, J.W.; Raab, G.; Mohr, U.
Journal Article
1996Squamous metaplasia, lung, rat
Nolte, T.; Ernst, H.; Dungworth, D.L.
Book Article
1996Surfactant activity is decreased in patients after lung transplantation
Hohlfeld, J.M.; Tiryaki, E.; Hamm, H.; Heilmann, M.; Tschorn, H.; Schürmann, W.H. T.; Demertzis, S.; Schäfers, H.J.; Hoymann, H.G.; Wagner, T.O.F.; Fabel, H.
Journal Article
1996Tumours of the lower respiratory tract
Mohr, U.; Emura, M.; Dungworth, D.L.; Ernst, H.
Book Article
1995Alteration of pulmonary macrophage function by respiratory syncytial virus infection in vitro
Franke-Ullmann, G.; Pförtner, C.; Walter, P.; Steinmüller, C.; Lohmann-Matthes, M.-L.; Kobzik, L.; Freihorst, J.
Journal Article
1995Biobeständigkeit verschiedener Mineralfasertypen in der Rattenlunge nach intratrachealer Applikation
Bellmann, B.; Muhle, H.
Book
1995Bronchoalveolar lavage analysis following a subacute inhalation of various man-made mineral fibres in rats
Creutzenberg, O.; Bellmann, B.; Muhle, H.
Journal Article
1995Chemically induced pulmonary mucoepidermoid carcinoma in a female Wistar rat
Nolte, T.; Dungworth, D.L.; Ernst, H.; Kittel, B.; Rittinghausen, S.; Mohr, H.
Journal Article
1995Chronic inhalation exposure of Wistar rats and two different strains of mice to diesel engine exhaust, carbon black, and titanium dioxide
Heinrich, U.; Fuhst, R.; Rittinghausen, S.; Creutzenberg, O.; Bellmann, B.; Koch, W.; Levsen, K.
Journal Article
1995Neoplastic lung lesions in rat after chronic exposure to crystalline silica
Muhle, H.; Kittel, B.; Ernst, H.; Mohr, U.; Mermelstein, R.
Journal Article
1995Particle deposition, retention, and toxicity of poorly soluble dusts
Muhle, H.
Conference Paper
1995Phagocytosis and chemotaxis of rat alveolar macrophages after a combined or separate exposure to ozone and carbon black
Creutzenberg, O.; Bellmann, B.; Klingebiel, R.; Heinrich, U.; Muhle, H.
Conference Paper
1995Toxicity of man-made fibres
Muhle, H.
Conference Paper
1995A transgenic mouse model for lung adenocarcinoma
Sandmöller, A.; Halter, R.; Suske, G.; Paul, D.; Beato, M.
Journal Article
1994Carcinogenic effects of solid particles
Heinrich, U.
Conference Paper
1994Comparative investigation of the effects of zardaverine and theophylline on pulmonary function in rats
Hoymann, H.-G.; Heinrich, U.; Beume, R.; Kilian, U.
Journal Article
1994Comparative investigations of the biodurability of mineral fibers in the rat lung
Muhle, H.; Bellmann, B.; Pott, F.
Conference Paper
1994Effects of single and combined, subchronic exposure to ozone and soot particles on pulmonary surfactant phospholipids and associated protein A and on surface activity in rat lung lavage fluid
Klingebiel, R.; Heinrich, U.; Martin-Carrera, I.; Dettmer, M.; Kühn, A.; Bartsch, W.
Conference Paper
1994Elevated surfactant protein A in bronchoalveolar lavage fluids from sarcoidosis and hypersensitivity pneumonitis patients
Hamm, H.; Lührs, J.; Guzman, J.; Costabel, U.; Fabel, H.; Bartsch, W.
Journal Article
1994Estimation of a lifetime unit lung cancer risk for benzo(a)pyrene (BaP) based on tumor rates in rats exposed to coal tar/pitch condensation aerosol -CTP-
Heinrich, U.; Pott, F.; Roller, M.
Conference Paper, Journal Article
1994Estimation of a lifetime unit lung cancer risk for benzo/a/pyrene based on tumour rates in rats exposed to coal tar/pitch condensation aerosol
Heinrich, U.; Roller, M.; Pott, F.
Journal Article
1994Formation of DNA adducts in rat lung following chronic inhalation of diesel emissions, carbon black and titanium dioxide particles
Gallagher, J.; Heinrich, U.; George, M.; Hendee, L.; Phillips, D.H.; Lewtas, J.
Journal Article
1994Goblet cell metaplasia in the peripheral lung tissue of rats after chronic exposure to particles
Kittel, B.; Dungworth, D.L.; Mohr, U.
Conference Paper
1994Histological and ultrastructural alterations of the bronchioloalveolar region in the rat lung after chronic exposure to a pyrolized pitch condensate of carbon black, alone or in combination
Nolte, T.; Thiedemann, K.-U.; Dungworth, D.L.; Ernst, H.; Paulini, I.; Heinrich, U.; Dasenbrock, C.; Peters, L.; Ueberschär, S.; Mohr, U.
Journal Article
1994Induction of squamous cell carcinomas in the mouse lung after long-term inhalation of polycyclic aromatic hydrocarbon-rich exhausts
Schulte, A.; Ernst, H.; Peters, L.; Heinrich, U.
Journal Article
1994Inhalation exposure of rats to tar/pitch condensation aerosol or carbon black alone or in combination with irritant gases
Heinrich, U.; Peters, L.; Creutzenberg, O.; Dasenbrock, C.; Hoymann, H.-G.
Conference Paper
1994Investigation of the biodurability and carcinogenicity of different man-made mineral fibres
Bellmann, B.; Muhle, H.; Pott, F.
Conference Paper
1994Investigation of the biodurability of wollastonite and xonotlite
Bellmann, B.; Muhle, H.
Conference Paper
1994Investigation on the durability of man-made vitreous fibers in rat lungs
Bellmann, B.; Muhle, H.; Kamstrup, O.; Draeger, U.F.
Conference Paper
1994Investigation on the durability of man-made vitreous fibres in rat lungs. Final report
: Bellmann, B.
Report
1994Lung tumours in rats after intratracheal instillation of dusts
Pott, F.; Dungworth, D.L.; Heinrich, U.; Muhle, H.; Kamino, K.; Germann, P.-G.; Roller, M.; Rippe, R.M.; Mohr, U.
Conference Paper
1994Method for the description of differences in the filamentous structure of the cyctoskeleton in cultured cells
Kohler, M.; Aufderheide, M.; Ramm, D.
Journal Article
1994The nonspecific immune system of the lung
Lohmann-Matthes, M.-L.; Franke, G.
Conference Paper
1994Pathologic effects of inhaled particles in rat lungs - Associations between inflammatory and neoplastic processes
Dungworth, D.L.; Mohr, U.; Heinrich, U.; Ernst, H.; Kittel, B.
Conference Paper
1994Phagocytosis and chemotaxis of rat alveolar macrophages after a combined or separate exposure to ozone and carbon black
Creutzenberg, O.; Bellmann, B.; Klingebiel, R.; Heinrich, U.; Muhle, H.
Conference Paper
1994Respirationstrakt
Muhle, H.
Book Article
1994Toxic and carcinogenic effects of solid particles in the respiratory tract
: Mohr, U.; Dungworth, D.L.; Mauderly, J.L.; Oberdörster, G.
Conference Proceedings
1994Toxicokinetics of solid particles in chronic studies using diesel soot, carbon black, toner, titanium dioxide and quartz
Muhle, H.; Bellmann, B.; Creutzenberg, O.
Conference Paper
1994Untersuchungen zur Biobeständigkeit von Wollastonitfasern.
Bellmann, B.; Muhle, H.
Journal Article
1994The uteroglobin promoter targets expression of the SV40 T antigen to a variety of secretory epithelial cells in transgenic mice
Sandmöller, A.; Halter, R.; Gomez-La-Hoz, E.; Gröne, H.-J.; Suske, G.; Paul, D.; Beato, M.
Journal Article
1993Advances in controlled clinical inhalation studies
: Mohr, U.; Bates, D.V.; Fabel, H.; Utell, M.J.
Conference Proceedings
1993Assessment of pollutant-induced impairment of the pulmonary surfactant system by high-performance liquid chromatography
Klingebiel, R.; Winkeler, H.D.; Drenk, F.; Heinrich, U.
Conference Paper
1993Benign keratinizing cystic squamous cell tumour in the rat lung
Rittinghausen, S.
Conference Paper
1993Carcinogenic effects of solid particles
Heinrich, U.
Conference Paper
1993Does the pulmonary surfactant system yield meaningful parameters in inhalation toxicity studies? A review
Klingebiel, R.; Heinrich, U.
Conference Paper
1993Dust measurements at workplaces - State of the art and future demands
Koch, W.
Conference Paper
1993Effects of single and combined, subchronic exposure to ozone and soot particles on pulmonary surfactant phospholipids, associated protein A and on surface activity in rat lung lavage fluid
Klingebiel, R.; Heinrich, U.; Martin-Carrera, I.; Dettmer, M.; Kühn, A.; Bartsch, W.; Hoymann, H.-G.
Conference Paper
1993Effects of single and combined, subchronic exposure to ozone and soot particles on the pulmonary surfactant system and on biochemical and cellular markers of inflammation in the rat lung
Klingebiel, R.; Creutzenberg, O.; Bartsch, W.; Ernst, H.; Heinrich, U.; Muhle, H.
Journal Article
1993Goblet cell metaplasia in rat lungs after chronic exposure to particles
Kittel, B.; Dungworth, D.L.; Mohr, U.
Conference Paper
1993Investigation on the biodurability of chemically different stone wool fibres
Bellmann, B.; Muhle, H.; Kamstrup, O.; Draeger, U.F.
Conference Paper
1993Investigation on the biodurability of different man-made mineral fibres
Bellmann, B.; Muhle, H.
Conference Paper
1993Long-term inhalation exposure of rats and mice to diesel exhaust (DE), carbon black (CB), and titanium dioxide (TiO2)
Heinrich, U.; Fuhst, R.; Dasenbrock, C.; Muhle, H.; Koch, W.; Mohr, U.
Conference Paper
1993Morphological comparison between benign keratinizing cystic squameous cell tumours of the lung and squameous lesions of the skin in rats
Kittel, B.; Ernst, H.; Dungworth, D.L.; Rittinghausen, S.; Nolte, T.; Kamino, K.; Stuart, B.P.; Lake, S.G.; Cardesa, A.; Morawietz, G.; Mohr, U.
Journal Article
1993Morphology and histogenesis of squamous cell metaplasia of the rat lung after chronic exposure to a pyrolized pitch condensate and/or carbon black, or to combinations of pyrolized pitch condensate, carbon black and irritant gases
Nolte, T.; Thiedemann, K.-U.; Dungworth, D.L.; Ernst, H.; Paulini, I.; Heinrich, U.; Dasenbrock, C.; Peters, L.; Ueberschär, S.; Mohr, U.
Journal Article
1993Morphometric evaluation of inhaled particles in sections of the lung
Kohler, M.; Aufderheide, M.; Ramm, D.
Conference Paper
1993The new born NMRI mouse, a very sensitive animal model to measure the carcinogenic potential of a PAH-containing test atmosphere by inhalation exposure
Heinrich, U.; Peters, L.; Dasenbrock, C.; Kamino, K.; Pott, F.
Conference Paper
1993Pathologic effects of inhaled particles in rat lungs - Associations between inflammatory and neoplastic processes
Dungworth, D.L.; Mohr, U.; Heinrich, U.; Ernst, H.; Kittel, B.
Conference Paper
1993Phagocytosis and chemotaxis of rat alveolar macrophages after a combined or separate exposure to ozone and carbon black
Creutzenberg, O.; Bellmann, B.; Klingebiel, R.; Heinrich, U.; Muhle, H.
Conference Paper
1993Regeneration, differentiation, and neoplastic transformation of type II alveolar epithelial cells
Thiedemann, K.-U.; Paulini, I.; Lüthe, N.; Kreft, A.; Abel, U.; Glaser, U.; Mohr, U.
Conference Paper
1993Toxic and carcinogenic effects of solid particles in the respiratory tract. Abstracts
 
Conference Proceedings
1993Toxicokinetics of solid particles in chronic studies - An overview
Muhle, H.
Conference Paper
1992Chronic effects of intratracheally instilled nickel-containing particles in hamsters
Pott, F.; Bellmann, B.; Fuhst, R.; Mohr, U.; Muhle, H.; Takenaka, S.
Conference Paper
1992Effect of photocorrosion on cadmium sulfide suspensions applied in animal inhalation studies with CdS particles
Heinrich, U.; Kock, H.; König, H.P.; Peters, L.
Journal Article
1992Increased surfactant protein - a content in human alveolar macrophages in hypersensitivity pneumonitis
Wang, Y.-M.; Kalaycioglu, O.; Schoenfeld, B.; Bartsch, W.; Costabel, U.; Guzman, J.; Hamm, H.
Journal Article
1992Das kanzerogene Potential von Luftschadstoffen - die Bedeutung von Kfz-Abgasen
Heinrich, U.
Conference Paper
1992A new aerosol generating device for use in animal physiology
Hohlfeld, J.; White, R.; Koch, W.; Heinrich, U.
Conference Paper
1992Nonneoplastic lesions in the lungs
Dungworth, D.L.; Ernst, H.; Mohr, U.; Nolte, T.; Kamino, K.; Rittinghausen, S.
Book Article
1992Photocorrosion of cadmium sulfide suspensions applied in animal inhalation studies
Heinrich, U.; Kock, H.; König, H.P.; Peters, L.
Conference Paper
1992Primary pulmonary tumors
Rittinghausen, S.; Dungworth, D.L.; Ernst, H.; Mohr, U.
Book Article
1992Pulmonary carcinogenicity of cadmium by inhalation in animals
Heinrich, U.
Conference Paper
1992Standardization of aerosol delivery with a new aerosol generating device for use in animal physiology
Hohlfeld, J.; Hoymann, H.-G.; Koch, W.; Klingebiel, R.; Heinrich, U.
Conference Paper
1992Surfactant protein A -SPA- content in alveolar macrophages of hypersensitivity pneumonitis and sarcoidosis
Guzman, J.; Wang, Y.-M.; Kalaycioglu, O.; Hamm, H.; Bartsch, W.; Costabel, U.
Conference Paper
1992Surfactant protein A in bronchoalveolar lavage of sarcoidosis and hypersensitivity pneumonitis
Hamm, H.; Lührs, J.; Kühne, A.; Guzman, J.; Costabel, U.; Bartsch, W.; Fabel, H.
Conference Paper
1992The surfactant system of the adult lung - physiology and clinical perspectives
Hamm, H.; Fabel, H.; Bartsch, W.
Journal Article
1992Tierexperimentelle Inhalationsstudien zur Frage der tumorinduzierenden Wirkung von Dieselmotorabgasen und zwei Teststäuben
Heinrich, U.; Fuhst, R.; Mohr, U.
Book Article
1991Altered action organization in an N-methyl-N'-nitro-N-nitrosoguanidine-transformed pulmonary epithelial cell line
Gobert-Bohlen, A.; Emura, M.; Mohr, U.
Journal Article
1991Chronic inhalation study findings as a basis for proposing a new occupational dust exposure limit
Morrow, P.E.; Mermelstein, R.; Muhle, H.
Journal Article
1991Comparison of the protective effect of intravenous urodilatin (URO) or ANP against an acetylcholine(ACh)-induced bronchoconstriction in the rat in vivo
Flüge, T.; Hoymann, H.-G.; Hohlfeld, J.; Heinrich, U.; Fabel, H.; Wagner, T.O.F.
Journal Article
1991Effects of 12 weeks exposure to a diisocyanate -MDI- on the pulmonary surfactant system and bronchoalveolar cell content in rats
Klingebiel, R.; Creutzenberg, O.; Hoymann, H.-G.; Dettmer, M.; Schüler, T.; Heinrich, U.
Conference Paper
1991How does the solubility of cadmium sulfide -CdS- affect the results of the inhalation studies with CdS particles?
Heinrich, U.; Kock, H.; König, H.P.; Peters, L.
Conference Paper
1991Immunohistochemistry and morphology of particle-induced pulmonary lesions
Ernst, H.; Nolte, T.; Rittinghausen, S.; Thiedemann, K.-U.
Book Article
1991Lung clearance and retention of toner, utilizing a tracer technique, during chronic inhalation exposure in rats.
Kilpper, R.; MacKenzie, J.C.; Morrow, P.E.; Bellmann, B.; Creutzenberg, O.; Dasenbrock, C.; Mermelstein, R.; Muhle, H.
Journal Article
1991Pulmonary response to toner upon chronic inhalation exposure in rats.
Kilpper, R.; MacKenzie, J.C.; Morrow, P.E.; Bellmann, B.; Creutzenberg, O.; Dasenbrock, C.; Ernst, H.; Mermelstein, R.; Mohr, U.; Muhle, H.; Takenaka, S.
Journal Article
1991Respiratory syncytial virus induced alteration of cytokine secretion by alveolar macrophages in vitro
Freihorst, J.; Verhagen, W.; Franke, G.; Hockertz, S.; Lohmann-Matthes, M.-L.
Conference Paper
1990Alveolar retention and clearance of insoluble particle in rats simulated by a new physiology oriented compartmental kinetics model
Morawietz, G.; Morrow, P.E.; Stöber, W.
Journal Article
1990Behaviour of rat alveolar macrophages -AM- after inhalation of a polymer dust
Bellmann, B.; Creutzenberg, O.; Mermelstein, R.; Muhle, H.; Tschernig, T.
Conference Paper
1990Clearance and retention of inhaled diesel exhaust particles, carbon black, and titanium dioxide in rats at lung overload conditions
Bellmann, B.; Creutzenberg, O.; Fuhst, R.; Heinrich, U.; Koch, W.; Muhle, H.
Conference Paper
1990Correlative light, scanning and transmission electron microscopy of rat lungs after short-term exposure to cadmium compounds
Dasenbrock, C.; Paulini, I.; Thiedemann, K.-U.
Conference Paper
1990Dust overloading of lungs - investigations of various materials, species differences, and irreversibility of effects
Mermelstein, R.; Bellmann, B.; Creutzenberg, O.; Heinrich, U.; Muhle, H.
Conference Paper
1990Dust overloading of lungs after exposure of rats to particles of low solubility. Comparative studies
Mermelstein, R.; Bellmann, B.; Creutzenberg, O.; Heinrich, U.; Ketkar, M.; Muhle, H.
Journal Article
1990Entwicklung eines Typ II-Pneumozyten-Kulturmodells unter Verwendung undifferenzierter fetaler Lungenepithelzellen
Germann, P.-G.; Ueberschär, S.; Emura, M.; Mohr, U.; Gerull, A.
Journal Article
1990Histological observations and morphometric analysis in lungs of hamsters after long term inhalation of cadmium compounds
Aufderheide, M.; Dasenbrock, C.; Ernst, H.; Fuhst, R.; Heinrich, U.; Mohr, U.; Peters, L.; Rittinghausen, S.
Conference Paper
1990Irreversible pulmonary changes after dust overloading of lungs in rats
Bellmann, B.; Creutzenberg, O.; Mermelstein, R.; Muhle, H.
Conference Paper
1990Quantification of hyperplastic areas in hamster lungs after chronic inhalation of different cadmium compounds
Aufderheide, M.; Heinrich, U.; Mohr, U.; Thiedemann, K.-U.
Journal Article
1990Recovery behaviour after dust overloading of lungs in rats
Mermelstein, R.; Bellmann, B.; Creutzenberg, O.; Muhle, H.
Journal Article
1990Relative significance of different hydrocarbons for the carcinogenic potency of emissions from various incomplete combustion processes
Heinrich, U.; Pott, F.
Conference Paper
1990Subchronic inhalation study of toner in rats
Morrow, P.; Kilpper, R.; MacKenzie, J.; Mermelstein, R.; Bellmann, B.; Creutzenberg, O.; Fuhst, R.; Koch, W.; Mohr, U.; Muhle, H.; Takenaka, S.
Journal Article
1990Ultrastructural observations in mouse lungs after short term inhalation of cadmium compounds
Dasenbrock, C.; Paulini, I.; Thiedemann, K.-U.
Conference Paper
1990Ultrastructural observations in mouse lungs after short term inhalation of cadmium compounds
Dasenbrock, C.; Paulini, I.; Thiedemann, K.-U.
Journal Article
1990Ultrastructure of hamster and rat lungs after chronic inhalation exposure to cadmium compounds
Thiedemann, K.-U.; Kreft, A.; Lüthe, N.; Heinrich, U.; Glaser, U.; Abel, U.
Conference Paper
1990Untersuchung zur Beständigkeit chemisch unterschiedlicher Glasfasern in Rattenlungen
Bellmann, B.; Muhle, H.; Pott, F.
Journal Article
1989Carcinogenicity studies on natural and man made fibres with the intraperitoneal test in rats.
Pott, F.; Ziem, U.; Reiffer, F.-J.; Bellmann, B.; Rosenbruch, M.; Huth, G.; Roller, M.
Book Article
1989Comparative long-term animal inhalation studies using various particulate matter - objectives, experimental design and preliminary results
Dasenbrock, C.; Fuhst, R.; Heinrich, U.; Muhle, H.; Peters, L.; Pott, F.
Journal Article
1989Compartmental modeling of the long-term retention of insoluble particles deposited in the alveolar region of the lung
Stöber, W.; Morrow, P.E.; Hoover, M.D.
Journal Article
1989The effect of automotive exhaust exposure on the carcinogenicity of dipentylnitrosamine -DPN- in the respiratory tract of rats
Fuhst, R.; Heinrich, U.; Mohr, U.; Peters, L.
Journal Article
1989Exhaust-specific carcinogenic effects of polycyclic aromatic hydrocarbon and their significance for the estimation of the exhaust exposure-related lung cancer risk
Heinrich, U.
Book Article
1989Investigation on the carcinogenic effects of various cadmium compounds after inhalation exposure in hamsters and mice
Dasenbrock, C.; Ernst, H.; Heinrich, U.; König, H.; Peters, L.; Rittinghausen, S.
Journal Article
1989Lung response to test toner upon 2 year inhalation exposure in rats
Kilpper, R.; MacKenzie, J.; Dasenbrock, C.; Mermelstein, R.; Mohr, U.; Morrow, P.E.; Muhle, H.; Takenaka, S.
Journal Article
1989Modeling approaches - introduction
Stöber, W.
Conference Paper
1989Pulmonary function changes in rats after chronic and subchronic inhalation exposure to various particulate matter
Heinrich, U.; Hoymann, H.-G.; Mermelstein, R.; Muhle, H.
Journal Article
1989Quantification of proliferation lesions in hamster lungs after chronic exposure to cadmium aerosols
Aufderheide, M.; Riebe, M.; Kohler, M.; Thiedemann, K.-U.
Conference Paper
1989Reversibility of biochemical and cytological alterations in bronchoalveolar lavagate upon cessation of dust exposure
Kilpper, R.; Bellmann, B.; Creutzenberg, O.; Mermelstein, R.; Morrow, P.E.; Muhle, H.
Journal Article
1989Reversibility of clearance impairment after subchronic test toner inhalation
Kilpper, R.; Bellmann, B.; Creutzenberg, O.; Mermelstein, R.; Morrow, P.E.; Muhle, H.
Journal Article
1988Animal experiments with chemically treated fibres
Pott, F.; Matscheck, A.; Ziem, U.; Huth, F.; Muhle, H.
Journal Article
1988Carcinogenicity of cadmium - overview of experimental and epidemiological results and their influence on recommendations for maximum concentrations in the occupational area
Heinrich, U.
Conference Paper
1988Investigation of the lung carcinogenic potentials of sodium dichromate and Cr (VI/III) oxide aerosols in wistar rats
Glaser, U.; Hochrainer, D.; Oldiges, H.
Conference Paper
1988Morphological effects of nickel powders on the lung of Syrian golden hamsters
Bellmann, B.; Creutzenberg, O.; Mohr, U.; Muhle, H.; Takenaka, S.
Journal Article
1988Overloading of lung clearance chronic exposure of experimental animals to particle
Bellmann, B.; Heinrich, U.; Muhle, H.
Journal Article
1988Toxicity and carcinogenic risk after long-term inhalation of cd-compounds in wistar rats
Glaser, U.; Hochrainer, D.; Oldiges, H.
Conference Paper
1987Comparative study of bronchoalveolar lavage fluid - effect of species, age, and method of lavage
Henderson, R.F.; Mauderly, J.L.; Pickrell, J.A.; Hahn, F.F.; Rebar, A.H.; Muhle, H.
Journal Article
1987Contribution of polycyclic aromatic hydrocarbons and nitro-derivatives to the carcinogenic impact of diesel engine exhaust condensate evaluated by implantation into lungs of rats
Grimmer, G.; Brune, H.; Deutsch-Wenzel, R.; Dettbarn, G.; Jacob, J.; Naujack, K.-W.; Mohr, U.; Ernst, H.
Journal Article
1987Inhalation and injection experiments in rats to test the carcinogenicity of MMF
Pott, F.; Ziem, U.; Bellmann, B.; Muhle, H.; Takenaka, S.
Journal Article
1987Persistence of man-made mineral fibres -MMMF- and asbestos in rat lungs
Klöppel, H.; Bellmann, B.; König, H.; Muhle, H.; Pott, F.
Journal Article
1986Alveolar distribution of fly ash and of titanium dioxide after long-term inhalation by Wistar rats
Takenaka, S.; Dornhöfer-Takenaka, H.; Muhle, H.
Journal Article