Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2018Air-liquid interface in vitro models for respiratory toxicology research: Consensus workshop and recommendations
Lacroix, Ghislaine; Koch, Wolfgang; Ritter, Detlef; Gutleb, Arno C.; Larsen, Søren Thor; Loret, Thomas; Zanetti, Filippo; Constant, Samuel; Chortarea, Savvina; Rothen-Rutishauser, Barbara M.; Hiemstra, Pieter S.; Frejafon, Emeric; Hubert, Philippe; Gribaldo, Laura; Kearns, Peter; Aublant, Jean-Marc; Diabaté, Silvia; Weiss, Carsten; Groot, Antoinette de; Kooter, Ingeborg
Journal Article
2018Cerium oxide and barium sulfate nanoparticle inhalation affects gene expression in alveolar epithelial cells type II
Schwotzer, Daniela; Niehof, Monika; Schaudien, Dirk; Kock, Heiko; Hansen, Tanja; Dasenbrock, Clemens; Creutzenberg, Otto H.
Journal Article
2018Development and evaluation of an in vitro test system for toxicity screening of aerosols released from consumer products and first application to aerosols from a hair straightening process
Ritter, Detlef; Bitsch, Annette; Elend, Manfred; Schuchardt, Sven; Hansen, Tanja; Brodbeck, Carsten; Knebel, Jan; Fuchs, Anne; Gronewold, Claas; Fautz, Rolf
Journal Article
2018A methodology for the assessment of inhalation exposure to aluminium from antiperspirant sprays
Schwarz, Katharina; Pappa, Gerlinde; Miertsch, Heike; Scheel, Julia; Koch, Wolfgang
Journal Article
2015Efficacy and safety of inhaled calcium lactate PUR118 in the ozone challenge model - a clinical trial
Holz, Olaf; Biller, Heike; Müller, Meike; Kane, Katie; Rosano, Molly; Hanrahan, John; Hava, David L.; Hohlfeld, Jens M.
Journal Article
2013A novel continuous powder aerosolizer (CPA) for inhalative administration of highly concentrated recombinant surfactant protein-C (rSP-C) surfactant to preterm neonates
Pohlmann, Gerhard; Iwatschenko, P.; Koch, Wolfgang; Windt, Horst; Rast, M.; Gama de Abreu, M.; Taut, F.J.H.; Muynck, C. de
Journal Article
2013Pulmonary toxicity of printer toner following inhalation and intratracheal instillation
Morimoto, Yasuo; Oyabu, Takako; Horie, Masanori; Kambara, Tatsunori; Izumi, Hiroto; Kuroda, Etsushi; Creuzenberg, Otto; Bellmann, Bernd; Pohlmann, Gerhard; Schuhardt, Sven; Hansen, Tanja; Ernst, Heinrich
Journal Article
2011Evaluation of reproductive/developmental and repeated dose (subchronic) toxicity and cytogenetic effects in rats of a roofing asphalt fume condensate by nose-only inhalation
Parker, C.M.; Schreiner, C.A.; Hallmark, N.; Kriech, A.J.; Osborn, L.V.; Fuhst, R.; Buschmann, J.; Ernst, H.; Hansen, T.; Pohlmann, G.; Preiß, A.; Ziemann, C.
Journal Article
2010Genotoxicity testing of sulfur dioxide (SO2) in a mouse bone marrow micronucleus test complemented with hematological endpoints
Ziemann, C.; Hansen, T.; Pohlmann, G.; Farrar, D.; Pohlenz-Michel, C.; Tillmann, T.; Mangelsdorf, I.
Journal Article
2008Biozidexposition aus Produkten des täglichen Bedarfs
Heger, W.; Hahn, S.; Schneider, K.; Gartiser, S.; Mangelsdorf, I.; Kolossa-Gehring, M.
Journal Article
2008Biozidexposition aus Produkten des täglichen Bedarfs
Heger, W.; Hahn, S.; Schneider, K.; Gartiser, S.; Mangelsdorf, I.; Kolossa-Gehring, M.
Journal Article
2001Chronic pulmonary effects of respirable methylene diphenyl diisocyanate (MDI) aerosol in rats
Feron, V.J.; Kittel, B.; Kuper, C.F.; Ernst, H.; Rittinghausen, S.; Muhle, H.; Koch, W.; Gamer, A.; Mallett, A.K.; Hoffmann, H.D.
Journal Article
199632P-Postlabeling of a DNA adduct derived from 4,4'-methylenedianiline in the olfactory epithelium of rats exposed by inhalation to 4,4'methylenephenyl diisocyanate
Vock, E.H.; Hoymann, H.-G.; Heinrich, U.; Lutz, W.K.
Journal Article
1995Untersuchungen zur chronischen Toxizität/Kanzerogenität von 4,4'-Methylendiphenyl-Diisocyanat (MDI). Bd.1
Hoymann, Heinz-Gerd; Buschmann, Jochen; Heinrich, Uwe
Report
1994Nasal retention and clearance of wood dust in rats
Creutzenberg, O.; Muhle, H.; Bellmann, B.
Journal Article
1993Assessment of pollutant-induced impairment of the pulmonary surfactant system by high-performance liquid chromatography
Klingebiel, R.; Winkeler, H.D.; Drenk, F.; Heinrich, U.
Conference Paper
1993Does the pulmonary surfactant system yield meaningful parameters in inhalation toxicity studies? A review
Klingebiel, R.; Heinrich, U.
Conference Paper
1993Generation of complex aerosols
Holländer, W.
Conference Paper
1993Regeneration, differentiation, and neoplastic transformation of type II alveolar epithelial cells
Thiedemann, K.-U.; Paulini, I.; Lüthe, N.; Kreft, A.; Abel, U.; Glaser, U.; Mohr, U.
Conference Paper
1992Irreversible pulmonary changes induced in rat lung by dust overload
Bellmann, B.; Creutzenberg, O.; Mermelstein, R.; Muhle, H.
Conference Paper
1992On the influence of different housing conditions and a sham inhalation exposure of rats on teratological endpoints
Buschmann, J.
Journal Article
1991Effects of subchronic exposure to a diisocyanate -MDI- on the pulmonary surfactant system and lung function.
Martin-Carrera, I.; Klingebiel, R.; Hoymann, H.G.; Heinrich, U.
Conference Paper
1991Immunohistochemistry and morphology of particle-induced pulmonary lesions
Ernst, H.; Nolte, T.; Rittinghausen, S.; Thiedemann, K.-U.
Book Article
1990Clearance and retention of inhaled diesel exhaust particles, carbon black, and titanium dioxide in rats at lung overload conditions
Bellmann, B.; Creutzenberg, O.; Fuhst, R.; Heinrich, U.; Koch, W.; Muhle, H.
Conference Paper
1990Correlative light, scanning and transmission electron microscopy of rat lungs after short-term exposure to cadmium compounds
Dasenbrock, C.; Paulini, I.; Thiedemann, K.-U.
Conference Paper
1990Dust overloading of lungs - investigations of various materials, species differences, and irreversibility of effects
Mermelstein, R.; Bellmann, B.; Creutzenberg, O.; Heinrich, U.; Muhle, H.
Conference Paper
1990Erzeugung und Überwachung von Aerosolen für Inhalationsexperimente
Koch, W.
Journal Article
1990Histological observations and morphometric analysis in lungs of hamsters after long term inhalation of cadmium compounds
Aufderheide, M.; Dasenbrock, C.; Ernst, H.; Fuhst, R.; Heinrich, U.; Mohr, U.; Peters, L.; Rittinghausen, S.
Conference Paper
1990Investigation of irritating properties of inhaled CrVI with possible influence on its charcinogen action.
Steinhoff, D.; Glaser, U.; Hochrainer, D.
Conference Paper
1990Irreversible pulmonary changes after dust overloading of lungs in rats
Bellmann, B.; Creutzenberg, O.; Mermelstein, R.; Muhle, H.
Conference Paper
1990Qualitative and quantitative ultrastructural investigations in hamster lungs after chronic inhalation of cadmium compounds
Thiedemann, K.-U.; Kreft, A.; Abel, U.; Dasenbrock, C.; Fuhst, R.; Peters, L.; Heinrich, U.; Mohr, U.
Conference Paper
1990Quantification of hyperplastic areas in hamster lungs after chronic inhalation of different cadmium compounds
Aufderheide, M.; Heinrich, U.; Mohr, U.; Thiedemann, K.-U.
Journal Article
1990Recovery behaviour after dust overloading of lungs in rats
Mermelstein, R.; Bellmann, B.; Creutzenberg, O.; Muhle, H.
Journal Article
1990Subchronic inhalation study of toner in rats
Morrow, P.; Kilpper, R.; MacKenzie, J.; Mermelstein, R.; Bellmann, B.; Creutzenberg, O.; Fuhst, R.; Koch, W.; Mohr, U.; Muhle, H.; Takenaka, S.
Journal Article
1990Toxicokinetics and carcinogenicity of man-made fibres
Bellmann, B.
Conference Paper
1990Ultrastructural observations in mouse lungs after short term inhalation of cadmium compounds
Dasenbrock, C.; Paulini, I.; Thiedemann, K.-U.
Conference Paper
1990Ultrastructural observations in mouse lungs after short term inhalation of cadmium compounds
Dasenbrock, C.; Paulini, I.; Thiedemann, K.-U.
Journal Article
1990Ultrastructure of hamster and rat lungs after chronic inhalation exposure to cadmium compounds
Thiedemann, K.-U.; Kreft, A.; Lüthe, N.; Heinrich, U.; Glaser, U.; Abel, U.
Conference Paper
1989Comparative long-term animal inhalation studies using various particulate matter - objectives, experimental design and preliminary results
Dasenbrock, C.; Fuhst, R.; Heinrich, U.; Muhle, H.; Peters, L.; Pott, F.
Journal Article
1989The effect of automotive exhaust exposure on the carcinogenicity of dipentylnitrosamine -DPN- in the respiratory tract of rats
Fuhst, R.; Heinrich, U.; Mohr, U.; Peters, L.
Journal Article
1989An experimental animal study for risk assessment of indoor air pollutants.
Glaser, U.; Hochrainer, D.; Klein, W.; Otto, F.
Journal Article
1989Inhalation experiments on retention and lung clearance of asbestos in combination with cigarette-smoking
Bellmann, B.; Muhle, H.; Pott, F.; Spurny, K.R.
Conference Paper
1989Investigation on the carcinogenic effects of various cadmium compounds after inhalation exposure in hamsters and mice
Dasenbrock, C.; Ernst, H.; Heinrich, U.; König, H.; Peters, L.; Rittinghausen, S.
Journal Article
1989Lung response to test toner upon 2 year inhalation exposure in rats
Kilpper, R.; MacKenzie, J.; Dasenbrock, C.; Mermelstein, R.; Mohr, U.; Morrow, P.E.; Muhle, H.; Takenaka, S.
Journal Article
1989Pulmonary function changes in rats after chronic and subchronic inhalation exposure to various particulate matter
Heinrich, U.; Hoymann, H.-G.; Mermelstein, R.; Muhle, H.
Journal Article
1989Quantification of proliferation lesions in hamster lungs after chronic exposure to cadmium aerosols
Aufderheide, M.; Riebe, M.; Kohler, M.; Thiedemann, K.-U.
Conference Paper
1989Reversibility of biochemical and cytological alterations in bronchoalveolar lavagate upon cessation of dust exposure
Kilpper, R.; Bellmann, B.; Creutzenberg, O.; Mermelstein, R.; Morrow, P.E.; Muhle, H.
Journal Article
1989Reversibility of clearance impairment after subchronic test toner inhalation
Kilpper, R.; Bellmann, B.; Creutzenberg, O.; Mermelstein, R.; Morrow, P.E.; Muhle, H.
Journal Article
1989Ultrastructural observation in hamster and rat lungs after chronic inhalation of cadmium compounds
Glaser, U.; Heinrich, U.; Kreft, A.; Lüthe, N.; Paulini, I.; Thiedemann, K.-U.
Conference Paper
1988Carcinogenicity of cadmium - overview of experimental and epidemiological results and their influence on recommendations for maximum concentrations in the occupational area
Heinrich, U.
Conference Paper
1988Exposure facilities and aerosol generation and characterization for inhalation experiments
Holländer, W.
Book Article
1988Investigation of the lung carcinogenic potential of sodium dichromate and Cr
Glaser, U.; Hochrainer, D.; Oldiges, H.
Conference Paper
1988Investigation of the lung carcinogenic potentials of sodium dichromate and Cr (VI/III) oxide aerosols in wistar rats
Glaser, U.; Hochrainer, D.; Oldiges, H.
Conference Paper
1988Long-term inhalation study of test toner in rats.
Kilpper, R.; MacKenzie, J.; Morrow, P.; Dasenbrock, C.; Koch, W.; Mermelstein, R.; Mohr, U.; Muhle, H.
Conference Paper
1988Morphological effects of nickel powders on the lung of Syrian golden hamsters
Bellmann, B.; Creutzenberg, O.; Mohr, U.; Muhle, H.; Takenaka, S.
Journal Article
1988Overloading of lung clearance chronic exposure of experimental animals to particle
Bellmann, B.; Heinrich, U.; Muhle, H.
Journal Article
1988Pulmonary deposition, clearance and retention of test toner, TIO2 and quartz during a long term inhalation study in rats.
Kilpper, R.; Mackenzie, J.; Morrow, P.; Bellmann, B.; Creutzenberg, O.; Mermelstein, R.; Muhle, H.; Stoeber, W.
Conference Paper
1988A subchronic inhalation study of a special test toner in rats.
Kilpper, R.; Creutzenberg, O.; Mermelstein, R.; Mohr, U.; Muhle, H.; Takenaka, S.
Conference Paper
1988Toxicity and carcinogenic risk after long term inhalation of cadmium compounds in Wistar-rats.
Glaser, U.; Hochrainer, D.; Oldiges, H.
Conference Paper
1987Untersuchungen über den Einfluß nicht-toxischer Stäube auf die Lungenreinigung und die Funktion der Alveolarmakrophagen
Koenig, H.; Lohmann-Matthes, M.-L.; Bellmann, B.; Creutzenberg, O.; Koch, W.; Muhle, H.; Takenaka, S.
Book
1986Alveolar distribution of fly ash and of titanium dioxide after long-term inhalation by Wistar rats
Takenaka, S.; Dornhöfer-Takenaka, H.; Muhle, H.
Journal Article
1986Bioavailability indicators of inhaled cadmium compounds.
Kloeppel, H.; Glaser, U.; Hochrainer, D.
Journal Article
1986Clearance of inhaled insoluble particle from the alveolar regions via the extraalveolar perivascular sheath
Muhle, H.; Takenaka, S.
Conference Paper
1986The generation and the measurement of dry aerosol in large-scale inhalation experiments
Koch, W.; Lödding, H.; Muhle, H.; Önning, G.
Journal Article
1986Inhalation and injection experiments in rats for testing carcinogenicity of MMMF
Ziem, U.; Bellmann, B.; Muhle, H.; Pott, F.; Takenaka, S.
Conference Paper
1986The inhalative toxicity of different cadmium compounds in rats.
Glaser, U.; Oldiges, H.
Conference Paper
1986Langzeit-Inhalationsversuch mit vier verschiedenen Cadmium-Verbindungen an Ratten
Glaser, U.; Hochrainer, D.; Oldiges, H.
Journal Article
1986Pulmonale Clearance von inhalierten Partikeln in Abhängigkeit von der Partikelgröße.
Bellmann, B.; Muhle, H.
Journal Article
1985Carcinogeicity of sodium dichromate and chromium
Kloeppel, H.; Glaser, U.; Hochrainer, D.; Oldiges, H.
Journal Article
1984Alveolar proteinosis induced in rats by long-term inhalation of nickel oxide
Hochrainer, D.; Oldiges, H.; Takenaka, S.
Conference Paper
1983Carcinogenicity of cadmium chloride aerosols in w-rats
Takenaka, S.; Oldiges, H.; Koenig, H.; Oberdoerster, G.; Hochrainer, D.
Conference Paper
1983Generation of aerosols from heavy metals for inhalation experiments.
Hochrainer, D.
Book Article
1983Lung carcinomas in rats after low level cadmium chloride inhalation
Koenig, H.; Oberdoerster, G.; Hochrainer, D.; Oldiges, H.; Takenaka, S.
Book Article
1982Carcinogenicity of cadmium-aerosols in wistar-rats
Koenig, H.; Oberdoerster, G.; Hochrainer, D.; Oldiges, H.; Takenaka, S.
Book Article
1981Ultrastructural alterations in the livers of golden hamsters following experimental chronic inhalation of diluted diesel exhaust emission
Meiß, R.; Robenek, H.; Schubert, M.; Themann, H.; Heinrich, U.
Journal Article