Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2019Transplantation of bone marrow derived macrophages reduces markers of neuropathology in an APP/PS1 mouse model
Costa-Marques, Luís; Arnold, Katrin; Pardon, Marie-Christine; Leovsky, Christiane; Swarbrick, Samantha; Fabian, Claire; Stolzing, Alexandra
Journal Article
2018Aβ oligomer eliminating compounds interfere successfully with pEAβ(3-42) induced motor neurodegenerative phenotype in transgenic mice
Dunkelmann, Tina; Teichmann, Kerstin; Ziehm, Tamar; Schemmert, Sarah; Frenzel, Daniel; Tusche, Markus; Dammers, Christina; Jürgens, Dagmar; Langen, Karl-Josef; Demuth, Hans-Ulrich; Shah, Nadim Jon; Kutzsche, Janine; Willuweit, Antje; Willbold, Dieter
Journal Article
2017Distribution pattern following systemic mesenchymal stem cell injection depends on the age of the recipient and neuronal health
Fabian, Claire; Naaldijk, Yahaira; Leovsky, Christiane; Johnson, Adiv A.; Rudolph, Lukas; Jäger, Carsten; Arnold, Katrin; Stolzing, Alexandra
Journal Article
2017Effect of systemic transplantation of bone marrow-derived mesenchymal stem cells on neuropathology markers in APP/PS1 Alzheimer mice
Naaldijk, Yahaira; Jäger, Carsten; Fabian, Claire; Leovsky, Christiane; Blüher, A.; Rudolph, Lukas; Hinze, Arnd; Stolzing, Alexandra
Journal Article
2017Recent progress in translational research on neurovascular and neurodegenerative disorders
Demuth, Hans-Ulrich; Dijkhuizen, Rick M.; Farr, Tracy D.; Gelderblom, Mathias; Horsburgh, Karen; Iadecola, Costantino; Mcleod, Damian D.; Michalski, Dominik; Murphy, Tim H.; Orbe, Josune; Otte, Wilem M.; Petzold, Gabor C.; Plesnila, Nikolaus; Reiser, Georg; Reymann, Klaus G.; Rueger, Maria P.; Saur, Dorothee; Savitz, Sean; Schilling, Stephan; Spratt, Neil J.; Turner, Renée J.; Vermuganti, Raghu; Vivien, Denis; Yepes, Manuel; Zille, Marietta; Boltze, Johannes
Journal Article
2016Enhanced fibril fragmentation of N-terminally truncated and Pyroglutamyl-modified Aβ peptides
Wulff, Melanie; Baumann, Monika; Thümmler, Anka; Yadav, Jay K.; Heinrich, Liesa; Knüpfer, Uwe; Schlenzig, Dagmar; Schierhorn, Angelika; Rahfeld, Jens-Ulrich; Horn, Uwe; Balbach, Jochen; Demuth, Hans-Ulrich; Fändrich, Marcus
Journal Article
2015Characterizing aging, mild cognitive impairment, and dementia with blood-based biomarkers and neuropsychology
Kleinschmidt, Martin; Schoenfeld, Robby; Göttlich, Claudia; Bittner, Daniel; Metzner, Jürgen Erich; Leplow, Bernd; Demuth, Hans-Ulrich
Journal Article
2015Detection and Quantification of β-Amyloid, Pyroglutamyl Aβ, and Tau in Aged Canines
Schmidt, Franziska; Boltze, Johannes; Jäger, Carsten; Hofmann, Sarah; Willems, Nicole; Seeger, Johannes; Härtig, Wolfgang; Stolzing, Alexandra
Journal Article
2014Environment-aware system for Alzheimer's patients
Barreto, Ana; Oliveira, Renato; Sousa, Filipe; Cardoso, Artur; Duarte, Cândido
Conference Paper
2014Glutaminyl cyclase in human cortex: Correlation with (pGlu)-amyloid-β load and cognitive decline in Alzheimer's disease
Morawski, Markus; Schilling, Stephan; Kreuzberger, Moritz; Waniek, Alexander; Jäger, Carsten; Koch, Birgit; Cynis, Holger; Kehlen, Astrid; Arendt, Thomas; Hartlage-Rübsamen, Maike; Demuth, Hans-Ulrich; Roßner, Steffen
Journal Article
2014Health care for people with dementia in 2030 - results of a multidisciplinary scenario process
Vollmar, H.C.; Goluchowicz, K.; Beckert, B.; Dönitz, E.; Bartholomeyczik, S.; Ostermann, T.; Boustani, M.; Buscher, I.
Journal Article
2014Pin1 promotes degradation of Smad proteins and their interaction with phosphorylated tau in Alzheimer's disease
Ueberham, Uwe; Rohn, Susanne; Ueberham, Elke; Wodischeck, Susanne; Hilbrich, Isabel; Holzer, Max; Brückner, Martina K.; Gruschka, Hildegard; Arendt, Thomas
Journal Article
2013Glutaminyl cyclase-mediated toxicity of pyroglutamate-beta amyloid induces striatal neurodegeneration
Becker, Andreas; Kohlmann, Stephanie; Alexandru, Anca; Jagla, Wolfgang; Canneva, Fabio; Bäuscher, Christoph; Cynis, Holger; Sedlmeier, Reinhard; Graubner, Sigrid; Schilling, Stephan; Demuth, Hans-Ulrich; Hörsten, Stephan von
Journal Article
2013A quantitative analysis of spontaneous isoaspartate formation from N-terminal asparaginyl and aspartyl residues
Güttler, Bert H.-O.; Cynis, Holger; Seifert, Franziska; Ludwig, Hans-Henning; Porzel, Andrea; Schilling, Stephan
Journal Article
2013STAlz: Remotely supporting the diagnosis, tracking and rehabilitation of patients with Alzheimer's
Moreira, Helder; Oliveira, Renato; Flores, Nuno
Conference Paper
2012Lack of detectable diffuse or neuritic plaques and neurofibrillary tangles in the brains of aged hamsters
Gerhauser, Ingo; Wohlsein, Peter; Ernst, Heinrich; Germann, Paul-Georg; Baumgärtner, Wolfgang
Journal Article
2012Neurovascular pathophysiology in cerebral ischemia, dementia and the ageing brain - current trends in basic, translational and clinical research
Boltze, Johannes; Kleinschnitz, Christoph; Reymann, Klaus G.; Reiser, Georg; Wagner, Daniel-Christoph; Kranz, Alexander; Michalski, Dominik
Journal Article
2012Structural analysis of the pyroglutamate-modified isoform of the Alzheimer's disease-related amyloid-β using NMR spectroscopy
Sun, Na; Hartmann, Rudolf; Lecher, Justin; Stoldt, Matthias; Funke, Susanne Aileen; Gremer, Lothar; Ludwig, Hans-Henning; Demuth, Hans-Ulrich; Kleinschmidt, Martin; Willbold, Dieter
Journal Article
2009Was die hausärztliche Leitlinie empfiehlt. Versorgung von Patienten mit Alzheimer-Demenz
Vollmar, H.C.
Journal Article
2006Simultaneous detection of tau phospho-epitopes with haptenylated antibodies
Härtig, W.; Lehmann, J.; Stieler, J.; Singer, D.; Grosche, J.; Arendt, T.; Hoffmann, J.
Journal Article
2006Temporal horn index and volume of medial temporal lobe atrophy using a new semiautomated method for rapid and precise assessment
Giesel, F.L.; Hahn, H.K.; Thomann, P.A.; Widjaja, E.; Wignall, E.; Tengg-Kobligk, H. von; Pantel, J.; Griffiths, P.D.; Peitgen, H.-O.; Schroder, J.; Eßig, M.
Journal Article