Winkler, C.; Hochdörfer, T.; Israelsson, E.; Hasselberg, A.; Cavallin, A.; Thörn, K.; Muthas, D.; Shojaee, S.; Lüer, K.; Müller, M.; Mjösberg, J.; Vaarala, O.; Hohlfeld, J.; Pardali, K.:
Activation of group 2 innate lymphoid cells after allergen challenge in asthmatic patients: Asthma and lower airway disease
The journal of allergy and clinical immunology : JACI, Vol.144 (2019), No.1, pp.61-69.e7
info:doi/10.1016/j.jaci.2019.01.027
Fraunhofer ITEM


Reamon-Buettner, S.M.; Voepel, I.; Hiemisch, A.; Eckert, V.; Schaudien, D.; Ziemann, C.:
Adverse effects of long and straight multiwalled carbon nanotubes on cytoskeleton, nuclear lamina, and genome-wide transcriptome of primary human mesothelial cells. (German Society for Experimental and Clinical Pharmacology and Toxicology (DGPT Annual Meeting) <85, 2019, Stuttgart>)
Naunyn-Schmiedebergs archives of pharmacology, Vol.392 (2019), Supplement 1, pp.S72
Fraunhofer ITEM


Weiser, Dieter; Appel, Bernhard; Buschmann, Carsten; Clevermann, Konstantin; Färber, Christa; Heina, Martina; Kühn, Michael; Kwiatkowski, Eberhard; Klappauf, Eberhard; Layher, Christof; Terhechte, Arno:
Allgemeiner Datenintegritätsstandard für Laborgerätesoftware
Bertini, R.: Datenintegrität in der pharmazeutischen Industrie: Anwendung - Praxisbeispiele - Audit Trail. Aulendorf: ECV Editio Cantor Verlag, 2019, pp. 215-230
Fraunhofer ITEM


Moradi Afrapoli, Fatemeh; Escher, Sylvia E.; Bitsch, Annette; Simetska, Nelly:
Analyses of frequency and sensitivity of affected organs in preclinical studies from RepDose and eTOX database. (German Society for Experimental and Clinical Pharmacology and Toxicology (DGPT Annual Meeting) <85, 2019, Stuttgart>)
Naunyn-Schmiedebergs archives of pharmacology, Vol.392 (2019), Supplement 1, pp.S67, Abstract P165
Fraunhofer ITEM


Rothbart, N.; Holz, O.; Koczulla, R.; Schmalz, K.; Hübers, H.-W.:
Analysis of Human Breath by Millimeter-Wave/Terahertz Spectroscopy
Sensors. Online journal, Vol.19 (2019), No.12, Art. 2719, 12 pp.
info:doi/10.3390/s19122719
Fraunhofer ITEM


Weiss, T.S.; Lupke, M.; Dayoub, R.; Geissler, E.K.; Schlitt, H.J.; Melter, M.; Eggenhofer, E.:
Augmenter of Liver Regeneration Reduces Ischemia Reperfusion Injury by Less Chemokine Expression, Gr-1 Infiltration and Oxidative Stress
Cells, Vol.8 (2019), No.11, Art. 1421, 15 pp.
urn:nbn:de:0011-n-5828830
info:doi/10.3390/cells8111421
Volltext
Fraunhofer ITEM


Prasse, Antje; Binder, Harald; Schupp, Jonas C.; Kayser, Gian; Bargagli, Elena; Jäger, Benedikt; Hess, Moritz; Rittinghausen, Susanne; Vuga, Louis; Lynn, Heather; Violette, Shelia; Jung, Birgit; Quast, Karsten; Vanaudenaerde, Bart; Xu, Yan; Hohlfeld, Jens M.; Krug, Norbert; Herazo-Maya, Jose D.; Rottoli, Paola; Wuyts, Wim A.; Kaminski, Naftali:
BAL cell gene expression is indicative of outcome and airway basal cell involvement in idiopathic pulmonary fibrosis
American Journal of Respiratory and Critical Care Medicine, Vol.199 (2019), No. 5, pp.622-630
info:doi/10.1164/rccm.201712-2551OC
Fraunhofer ITEM


Hohlfeld, Jens M.; Badorrek, Philipp; Faulenbach, Cornelia; Hohl, Kathrin; Litzenburger, T.; Müller, Meike; Sarno, Maria; Seibold, Wolfgang; Gupta, A.:
BI 1026706, a Bradykinin 1 Antagonist, Did Not Reduce Pulmonary Inflammation Upon Segmental Endotoxin Challenge in Healthy Current Smoker Subjects Compared with Placebo. (American Thoracic Society (ATS International Conference) <2019, Dallas/Tex.>)
American Journal of Respiratory and Critical Care Medicine, Vol.199 (2019), Abstract A4874
info:doi/10.1164/ajrccm-conference.2019.199.1_MeetingAbstracts.A4874
Fraunhofer ITEM


Prasse, Antje; Jäger, Benedikt; Schupp, Jonas C.; Kaminski, Naftali; Carleo, Alfonso:
Bronchoalveolar Cell Transcriptome of Acute Exacerbation in Idiopathic Pulmonary Fibrosis. (American Thoracic Society (ATS International Conference) <2019, Dallas/Tex.>)
American Journal of Respiratory and Critical Care Medicine, Vol.199 (2019), Abstract A5259, 1 pp.
info:doi/10.1164/ajrccm-conference.2019.199.1_MeetingAbstracts.A5259
Fraunhofer ITEM


Riquelme, P.; Geissler, E.K.; Hutchinson, J.A.:
C5aR1 governs Mreg migration, development, and function
American journal of transplantation, Vol.19 (2019), No.3, pp.619-621
info:doi/10.1111/ajt.15153
Fraunhofer ITEM


Schuchardt, S.; Koch, W.; Rosenberger, W.:
Cabin air quality – Quantitative comparison of volatile air contaminants at different flight phases during 177 commercial flights
Building and environment, Vol.148 (2019), pp.498-507
info:doi/10.1016/j.buildenv.2018.11.028
Fraunhofer ITEM


Geissler, Edward K.; Schlitt, Hans J.:
Can Mycophenolic Acid-based Immunosuppression Benefit Liver Transplant Patients with HCC?
Transplantation, Vol.103 (2019), No.5, pp.873-874
info:doi/10.1097/TP.0000000000002648
Fraunhofer ITEM


Escher, Sylvia E.; Cronin, Mark T.D.; Firman, J.; Magdziarz, T.; Rathman, J.; Yang, C.:
Cefic LRI AIMT-8: Prediction of STOTRE classification by new approach methodologies. (Society of Toxicology (Annual Meeting) <58, 2019, Baltimore/Md.>)
The Toxicologist, Vol.168 (2019), No.1, Abstract PS 1861
Fraunhofer ITEM


Ellison, C.A.; Blackburn, K.L.; Carmichael, P.L.; Clewell, H.J.; Cronin, M.T.D.; Desprez, B.; Escher, S.E.; Ferguson, S.S.; Grégoire, S.; Hewitt, N.J.; Hollnagel, H.M.; Klaric, M.; Patel, A.; Salhi, S.; Schepky, A.; Schmitt, B.G.; Wambaugh, J.F.; Worth, A.:
Challenges in working towards an internal threshold of toxicological concern (iTTC) for use in the safety assessment of cosmetics: Discussions from the Cosmetics Europe iTTC Working Group workshop
Regulatory toxicology and pharmacology, Vol.103 (2019), pp.63-72
info:doi/10.1016/j.yrtph.2019.01.016
Fraunhofer ITEM


Kermani, Bahram G.; Hücker, Sarah M.; Kirsch, Stefan; Polzer, Bernhard:
Challenges of screening applications for early detection of cancer using liquid biopsy. (American Association for Cancer Research (AACR Annual Meeting) <2019, Atlanta/Ga.>)
Cancer research, Vol.79 (2019), No.13, Supplement, Abstract 1625
info:doi/10.1158/1538-7445.AM2019-1625
Fraunhofer ITEM


Ehnes, C.; Genz, M.; Duwenhorst, J.; Krasnow, J.; Bleeke, J.; Schwarz, K.; Koch, W.; Schuchardt, S.:
Characterization of Aerosol Release during Spraying of Isocyanate Products
Annals of work exposures and health, Vol.63 (2019), No.7, pp.773-783
info:doi/10.1093/annweh/wxz045
Fraunhofer ITEM


Obernolte, Helena; Ritter, Detlef; Knebel, Jan; Niehof, Monika; Braubach, Peter; Jonigk, Danny; Warnecke, G.; Zardo, P.; Fieguth, H.-G.; Pfennig, Olaf; Braun, Armin; Sewald, Katherina:
Cigarette smoke induced pathophysiological changes in the extracellular matrix but not inflammation as early events in fresh human lung tissue. (Society of Toxicology (Annual Meeting) <58, 2019, Baltimore/Md.>)
The Toxicologist, Vol.168 (2019), No.1, Abstract PS 1940
Fraunhofer ITEM


Kreuter, M.; Swigris, J.; Pittrow, D.; Geier, S.; Klotsche, J.; Prasse, A.; Wirtz, H.; Koschel, D.; Andreas, S.; Claussen, M.; Grohé, C.; Wilkens, H.; Hagmeyer, L.; Skowasch, D.; Meyer, J.F.; Kirschner, J.; Gläser, S.; Kahn, N.; Welte, T.; Neurohr, C.; Schwaiblmair, M.; Held, M.; Bahmer, T.; Oqueka, T.; Frankenberger, M.; Behr, J.:
The clinical course of idiopathic pulmonary fibrosis and its association to quality of life over time: Longitudinal data from the INSIGHTS-IPF registry
Respiratory research. Online journal, Vol.20 (2019), Art.59, 13 pp.
info:doi/10.1186/s12931-019-1020-3
Fraunhofer ITEM


Watz, H.; Hohlfeld, J.M.; Singh, D.; Beier, J.; Scholz, V.; Diamant, Z.; Liu, J.; Hua, S.; Pinot, P.; Jones, I.; Sarkar, A.; Tillmann, H.:
The Combination of Indacaterol/Glycopyrronium/Mometasone Furoate Is Superior to High-Dose Salmeterol/Fluticasone Propionate in Improving Lung Function in Patients with Asthma. (American Thoracic Society (ATS International Conference) <2019, Dallas/Tex.>)
American Journal of Respiratory and Critical Care Medicine, Vol.199 (2019), Abstract A7081, 1 pp.
info:doi/10.1164/ajrccm-conference.2019.199.1_MeetingAbstracts.A7081
Fraunhofer ITEM


Lee, H.; Taylor-Just, A.; You, D.; Lison, D.; Brûle, S.; Ziemann, Christina; Creutzenberg, Otto H.; Simon, S.; Vulpoi, A.; Turcu, T.; Bonner, J.C.:
Comparative study of multiwalled carbon nanotubes and pro-inflammatory IL-1 beta production: The role of purification and surface functionalization. (Society of Toxicology (Annual Meeting) <58, 2019, Baltimore/Md.>)
The Toxicologist, Vol.168 (2019), No.1, Abstract PS 2046
Fraunhofer ITEM


Brocke, J. vom; Frericks, M.; Escher, S.E.; Anger, L.T.:
Computational Toxicology @ German Toxicology Society. (European Societies of Toxicology (EUROTOX Congress) <55, 2019, Helsinki>)
Toxicology letters, Vol.314 (2019), Supplement, pp.S248-S249
Fraunhofer ITEM


Kuo, C.-H.S.; Pavlidis, S.; Zhu, J.; Loza, M.; Baribaud, F.; Rowe, A.; Pandis, I.; Gibeon, D.; Hoda, U.; Sousa, A.; Wilson, S.J.; Howarth, P.; Shaw, D.; Fowler, S.; Dahlen, B.; Chanez, P.; Krug, N.; Sandstrom, T.; Fleming, L.; Corfield, J.; Auffray, C.; Djukanovic, R.; Sterk, P.J.; Guo, Y.; Adcock, I.M.; Chung, K.F.:
Contribution of airway eosinophils in airway wall remodeling in asthma: Role of MMP‐10 and MET
Allergy. European journal of allergy and clinical immunology, Vol.74 (2019), No.6, pp.1102-1112
info:doi/10.1111/all.13727
Fraunhofer ITEM


Toropova, A.P.; Toropov, A.A.; Marzo, M.; Escher, S.E.; Dorne, J.L.; Georgiadis, N.; Benfenati, E.:
Corrigendum to "The application of new HARD-descriptor available from the CORAL software to building up NOAEL models" [Food Chem. Toxicol. 112 (2018) 544-550]
Food and Chemical Toxicology : FCT, Vol.128 (2019), pp.146
info:doi/10.1016/j.fct.2019.04.004
Fraunhofer ITEM


Jäger, Benedikt; Schambach, A.; Denise, K.; Foley, M.; Prasse, Antje:
CXCR4 Inhibition by the I-Body Ad-114 Blocks Bronchosphere Formation in a 3d Organoid Model. (American Thoracic Society (ATS International Conference) <2019, Dallas/Tex.>)
American Journal of Respiratory and Critical Care Medicine, Vol.199 (2019), Abstract A5250, 1 pp.
info:doi/10.1164/ajrccm-conference.2019.199.1_MeetingAbstracts.A5250
Fraunhofer ITEM


Köhler, Sophia; Schulze, Mareike (Erstprüferin); Schauerte, Angelika (Zweitprüferin) :
Datenbankentwicklung zur Optimierung der Dokumentation von Rekrutierungsmaßnahmen für Probanden am Fraunhofer ITEM
Hannover, Hochschule, Bachelor Thesis, 2019
Fraunhofer ITEM


Yilmaz-Bayraktar, S.; Schwieger, J.; Scheper, V.; Lenarz, T.; Böer, U.; Kreienmeyer, M.; Torrente, M.; Doll, T.:
Decellularized equine carotid artery layers as matrix for regenerated neurites of spiral ganglion neurons
International journal of artificial organs, (2019), Online First, 11 pp.
info:doi/10.1177/0391398819868481
Fraunhofer ITEM


Nowak, Norman; Winkler, Daniel Sandro; Escher, Sylvia E.; Hansen, T.; Blümlein, Katharina; Schwarz, Katharina:
Development of a Physiologically Based Pharmacokinetic (PBPK) Model for the Inhalational Route. (International Society for Aerosols in Medicine (ISAM International Congress) <22, 2019, Montreux>)
Journal of aerosol medicine and pulmonary drug delivery, Vol.32 (2019), No.3, pp.A38, Abstract O-111
Fraunhofer ITEM


Wehr, M.; Karwath, A.; Sarang, S.S.; Rooseboom, M.; Boogaard, P.J.; Escher, S.E.:
Development of a QSAR model for respiratory irritation. (German Society for Experimental and Clinical Pharmacology and Toxicology (DGPT Annual Meeting) <85, 2019, Stuttgart>)
Naunyn-Schmiedebergs archives of pharmacology, Vol.392 (2019), Supplement 1, pp.S67
Fraunhofer ITEM


Wehr, Matthias; Karwath, A.; Sarang, S.S.; Rooseboom, M.; Boogaard, P.J.; Escher, Sylvia E.:
Development of a QSAR model to predict respiratory irritation by individual constituents. (Society of Toxicology (Annual Meeting) <58, 2019, Baltimore/Md.>)
The Toxicologist, Vol.168 (2019), No.1, Abstract PS 1854
Fraunhofer ITEM


Wilde, S.; Queisser, N.; Holz, C.; Raschke, M.; Sutter, A.:
Differentiation of Aneugens and Clastogens in the In Vitro Micronucleus Test by Kinetochore Scoring Using Automated Image Analysis
Environmental and Molecular Mutagenesis, Vol.60 (2019), No.3, pp.227-242
info:doi/10.1002/em.22259
Fraunhofer ITEM


Hansen, T.; Ritter, D.; Knebel, J.:
Dosing considerations for in vitro inhalation testing of VOCs in air-lifted Interphase (ALI) cultures. (European Societies of Toxicology (EUROTOX Congress) <55, 2019, Helsinki>)
Toxicology letters, Vol.314 (2019), Supplement, pp.S160
Fraunhofer ITEM


Vogel-Claussen, J.; Schönfeld, C.-O.; Kaireit, T.F.; Voskrebenzev, A.; Czerner, C.P.; Renne, J.; Tillmann, H.-C.; Berschneider, K.; Hiltl, S.; Bauersachs, J.; Welte, T.; Hohlfeld, J.M.:
Effect of Indacaterol/Glycopyrronium on Pulmonary Perfusion and Ventilation in Hyperinflated Patients with Chronic Obstructive Pulmonary Disease (CLAIM): A Double-Blind, Randomized, Crossover Trial
American Journal of Respiratory and Critical Care Medicine, Vol.199 (2019), No.9, pp.1086-1096
info:doi/10.1164/rccm.201805-0995OC
Fraunhofer ITEM


Herth, F.J.; Hohlfeld, J.M.; Haas, J.; Hoz, A. de la; Jin, X.; Kreitner, K.; Vogelmeier, C.F.; Vogel-Claussen, J.; Watz, H.:
The Effect of Tiotropium/Olodaterol versus Salmeterol/Fluticasone on Left Ventricular Function and Lung Hyperinflation in Patients with COPD. (American Thoracic Society (ATS International Conference) <2019, Dallas/Tex.>)
American Journal of Respiratory and Critical Care Medicine, Vol.199 (2019), Abstract A3308, 1 pp.
info:doi/10.1164/ajrccm-conference.2019.199.1_MeetingAbstracts.A3308
Fraunhofer ITEM


Beier, J.; Watz, H.; Scholz, V.; Diamant, Z.; Hohlfeld, J.M.; Singh, D.; Pinot, P.; Lheritier, K.; Sarkar, A.; Tillmann, H.:
The Efficacy of the Combination Indacaterol/Glycopyrronium/Mometasone Furoate Is Independent of Time of Dosing in Patients with Asthma. (American Thoracic Society (ATS International Conference) <2019, Dallas/Tex.>)
American Journal of Respiratory and Critical Care Medicine, Vol.199 (2019), Abstract A1277, 1 pp.
info:doi/10.1164/ajrccm-conference.2019.199.1_MeetingAbstracts.A1277
Fraunhofer ITEM


Schäfers, C.; Licht, O.; Bitsch, A.:
Endokrin wirksame Umweltchemikalien in Lebensmitteln
Deutsche Zeitschrift für klinische Forschung, Vol.23 (2019), No.3, pp.38-45
Fraunhofer IME
Fraunhofer ITEM


Danov, Olga; Martin, Gaël; Greif, A.; Bailly, B.; Braubach, Peter; Jonigk, Danny; Warnecke, Gregor; Itzstein, M. von; Sewald, Katherina; Wronski, Sabine; Braun, Armin:
Enhanced tissue damage following H1N1 infection in human precision-cut lung slices (PCLS). (American Thoracic Society (ATS International Conference) <2019, Dallas/Tex.>)
American Journal of Respiratory and Critical Care Medicine, Vol.199 (2019), Abstract A5742
Fraunhofer ITEM


Carstensen, Saskia; Holz, Olaf; Hohlfeld, Jens M.; Müller, Meike:
Eosinophil and Neutrophil Granulocyte Immunophenotyping Using Chipcytometry. (American Thoracic Society (ATS International Conference) <2019, Dallas/Tex.>)
American Journal of Respiratory and Critical Care Medicine, Vol.199 (2019), Abstract A2956
info:doi/10.1164/ajrccm-conference.2019.199.1_MeetingAbstracts.A2956
Fraunhofer ITEM


Perotin, J.-M.; Schofield, J.P.R.; Wilson, S.J.; Ward, J.; Brandsma, J.; Strazzeri, F.; Bansal, A.; Yang, X.; Rowe, A.; Corfield, J.; Lutter, R.; Shaw, D.E.; Bakke, P.S.; Caruso, M.; Dahlén, B.; Fowler, S.J.; Horváth, I.; Howarth, P.; Krug, N.; Montuschi, P.; Sanak, M.; Sandström, T.; Sun, K.; Pandis, I.; Auffray, C.; Meulder, B. de; Lefaudeux, D.; Riley, J.H.; Sousa, A.R.; Dahlen, S.-E.; Adcock, I.M.; Chung, K.F.; Sterk, P.J.; Skipp, P.J.; Collins, J.E.; Davies, D.E.; Djukanović, R.:
Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux
European Respiratory Journal, Vol.53 (2019), No.6, Art.1900453
info:doi/10.1183/13993003.00453-2019
Fraunhofer ITEM


Jevnikar, Z.; Östling, J.; Ax, E.; Calven, J.; Thörn, K.; Israelsson, E.; Öberg, L.; Singhania, A.; Lau, L.C.K.; Wilson, S.J.; Ward, J.A.; Chauhan, A.; Sousa, A.R.; Meulder, B. de; Loza, M.J.; Baribaud, F.; Sterk, P.J.; Chung, K.F.; Sun, K.; Guo, Y.; Adcock, I.M.; Payne, D.; Dahlen, B.; Chanez, P.; Shaw, D.E.; Krug, Norbert; Hohlfeld, Jens M.; Sandström, T.; Djukanovic, R.; James, A.; Hinks, T.S.C.; Howarth, P.H.; Vaarala, O.; Geest, M. van; Olsson, H.; Adcock, I.M.; Ahmed, H.; Auffray, C.; Bakke, P.; Bansal, A.T.; Baribaud, F.; Bates, S.; Bel, E.H.; Bigler, J.; Bisgaard, H.; Boedigheimer, M.J.; Bonnelykke, K.; Brandsma, J.; Brinkman, P.; Bucchioni, E.; Burg, D.; Bush, A.; Caruso, M.; Chaiboonchoe, A.; Chanez, P.; Chung, F.K.; Compton, C.H.; Corfield, J.; D'Amico, A.; Dahlen, S.E.; De Meulder, B.; Djukanovic, R.; Erpenbeck, V.J.; Erzen, D.; Fichtner, K.; Fitch, N.; Fleming, L.J.; Formaggio, E.; Fowler, S.J.; Frey, U.; Gahlemann, M.; Geiser, T.; Goss, V.; Guo, Y.; Hashimoto, S.; Haughney, J.; Hedlin,:
Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation
The journal of allergy and clinical immunology : JACI, Vol.143 (2019), No.2, pp.577-590
urn:nbn:de:0011-n-5155997
info:doi/10.1016/j.jaci.2018.05.026
Volltext
Fraunhofer ITEM


Molina, R.M.; Konduru, N.V.; Queiroz, P.M.; Figueroa, B.; Fu, D.; Ma-Hock, L.; Groeters, S.; Schaudien, D.; Brain, J.D.:
Fate of Barium Sulfate Nanoparticles Deposited in the Lungs of Rats
Scientific Reports, Vol.9 (2019), No.1, Art.8163, 13 pp.
info:doi/10.1038/s41598-019-44551-2
Fraunhofer ITEM


Molina, Ramon M.; Konduru, Nagarjun V.; Queiroz, Priscila M.; Figueroa, Benjamin; Fu, Dan; Ma-Hock, Lan; Gröters, Sibylle; Schaudien, Dirk; Brain, Joseph D.:
Fate of barium sulfate nanoparticles deposited in the lungs of rats. (American Thoracic Society (ATS International Conference) <2019, Dallas/Tex.>)
American Journal of Respiratory and Critical Care Medicine, Vol.199 (2019), Abstract A1844
Fraunhofer ITEM


Fraunhofer-Institut für Toxikologie und Experimentelle Medizin -ITEM-, Hannover:
Fraunhofer-Institut für Toxikologie und Experimentelle Medizin. Leistungen und Ergebnisse. Jahresbericht 2018
Hannover: Fraunhofer ITEM, 2019
urn:nbn:de:0011-n-5552987
Volltext
Fraunhofer ITEM


Apel, R.-M.; Prasse, Antje:
Geschlechtsspezifische Einflüsse auf die Lungenfibrose
Atemwegs- und Lungenkrankheiten, Vol.45 (2019), No.8, pp.407-411
info:doi/10.5414/atx02373
Fraunhofer ITEM


Zhang, J.; Empl, M.T.; Schneider, M.; Schröder, B.; Stadnicka-Michalak, J.; Breves, G.; Steinberg, P.; Sturla, S.J.:
Gut microbial transformation of the dietary mutagen MeIQx may reduce exposure levels without altering intestinal transport
Toxicology in vitro, Vol.59 (2019), pp.238-245
info:doi/10.1016/j.tiv.2019.04.004
Fraunhofer ITEM


Schramm, Sinja-Fee; Wehr, Matthias; Danov, Olga; Obernolte, Helena; Knebel, Jan; Koschmann, J.; Meckbach, C.; Niehof, Monika; Braubach, Peter; Jonigk, Danny; Hansen, Tanja; Braun, Armin; Sewald, Katherina; Escher, Sylvia E.:
Hazard characterisation of acrylates by in vitro and ex vivo models - an update of the ExITox project. (Society of Toxicology (Annual Meeting) <58, 2019, Baltimore/Md.>)
The Toxicologist, Vol.168 (2019), No.1, Abstract PS 1856
Fraunhofer ITEM


Hung, Lisa; Obernolte, Helena; Sewald, Katherina; Eiwegger, Thomas:
Human ex vivo and in vitro disease models to study food allergy
Asia Pacific allergy, Vol.9 (2019), No.1, Art. e4, 13 pp.
urn:nbn:de:0011-n-5660538
info:doi/10.5415/apallergy.2019.9.e4
Volltext
Fraunhofer ITEM


Sturla, S.; Zhang, J.; Hurley, K.; Empl, M.T.; Schneider, M.; Breves, G.; Steinberg, P.; Schwab, C.; Lacroix, C.:
Human gut microbial glycerol dehydratase function: impact on chemical metabolism and toxicological relevance. (European Societies of Toxicology (EUROTOX Congress) <55, 2019, Helsinki>)
Toxicology letters, Vol.314 (2019), Supplement, pp.S59
Fraunhofer ITEM


Marin, E.; Bouchet-Delbos, L.; Renoult, O.; Louvet, C.; Nerriere-Daguin, V.; Managh, A.J.; Even, A.; Giraud, M.; Vu Manh, T.P.; Aguesse, A.; Bériou, G.; Chiffoleau, E.; Alliot-Licht, B.; Prieur, X.; Croyal, M.; Hutchinson, J.A.; Obermajer, N.; Geissler, E.K.; Vanhove, B.; Blancho, G.; Dalod, M.; Josien, R.; Pecqueur, C.; Cuturi, M.C.; Moreau, A.:
Human Tolerogenic Dendritic Cells Regulate Immune Responses through Lactate Synthesis
Cell metabolism, Vol.30 (2019), No.6, pp.1075-1090
info:doi/10.1016/j.cmet.2019.11.011
Fraunhofer ITEM


Creutzenberg, Otto H.; Lison, D.; Brule, S. van den; Simon, S.; Bonner, J.C.; Ziemann, Christina:
ICONS - Integrated testing strategy for mechanistically assessing the respiratory toxicity of functionalized MWCNT. (Society of Toxicology (Annual Meeting) <58, 2019, Baltimore/Md.>)
The Toxicologist, Vol.168 (2019), No.1, Abstract PS 2232
Fraunhofer ITEM


Brinkman, P.; Wagener, A.H.; Hekking, P.-P.; Bansal, A.T.; Zee, A.-H. Maitland-van der; Wang, Y.; Weda, H.; Knobel, H.H.; Vink, T.J.; Rattray, N.J.; D'Amico, A.; Pennazza, G.; Santonico, M.; Lefaudeux, D.; Meulder, B. de; Auffray, C.; Bakke, P.S.; Caruso, M.; Chanez, P.; Chung, K.F.; Corfield, J.; Dahlén, S.-E.; Djukanovic, R.; Geiser, T.; Horvath, I.; Krug, Norbert; Musial, J.; Sun, K.; Riley, J.H.; Shaw, D.E.; Sandström, T.; Sousa, A.R.; Montuschi, P.; Fowler, S.J.; Sterk, P.J.:
Identification and prospective stability of electronic nose (eNose) - derived inflammatory phenotypes in patients with severe asthma
The journal of allergy and clinical immunology : JACI, Vol.143 (2019), No.5, pp.1811-1820
info:doi/10.1016/j.jaci.2018.10.058
Fraunhofer ITEM


Ernst, L.; Langer, N.; Bockelmann, A.; Salkhordeh, E.; Beuerle, T.:
Identification and quantification of synthetic cannabinoids in 'spice-like' herbal mixtures: Update of the German situation in summer 2018
Forensic science international, Vol.294 (2019), pp.96-102
info:doi/10.1016/j.forsciint.2018.11.001
Fraunhofer ITEM


Licht, O.; Bitsch, A.; Bohlen, M.L.; Escher, S.E.; Kass, G.; Merten, C.; MacLeod, M.; Noteborn, H.; Schwarz, M.; Oltmanns, J.; Silano, V.:
Identification of potential emerging chemical risks in food from REACH registered chemicals. (German Society for Experimental and Clinical Pharmacology and Toxicology (DGPT Annual Meeting) <85, 2019, Stuttgart>)
Naunyn-Schmiedebergs archives of pharmacology, Vol.392 (2019), Supplement 1, pp.S81
Fraunhofer ITEM


Bitsch, Annette; Bohlen, M.-L.; Escher, Sylvia E.; Kass, Georges; Licht, Oliver; MacLeod, M.; Merten, C.; Noteborn, H.; Oltmanns, Jan; Schwarz, M.; Silano, V.:
Identification of potential emerging chemical risks in food from REACH registered chemicals. (Society of Toxicology (Annual Meeting) <58, 2019, Baltimore/Md.>)
The Toxicologist, Vol.168 (2019), No.1, Abstract PS 2637
Fraunhofer ITEM


Östling, J.; Geest, M. van; Schofield, J.P.R.; Jevnikar, Z.; Wilson, S.; Ward, J.; Lutter, R.; Shaw, D.E.; Bakke, P.S.; Caruso, M.; Dahlen, S.-E.; Fowler, S.J.; Horvath, I.; Krug, N.; Montuschi, P.; Sanak, M.; Sandström, T.; Sun, K.; Pandis, I.; Auffray, C.; Sousa, A.R.; Guo, Y.; Adcock, I.M.; Howarth, P.; Chung, K.F.; Bigler, J.; Sterk, P.J.; Skipp, P.J.; Djukanović, R.; Vaarala, O.:
IL-17–high asthma with features of a psoriasis immunophenotype
The journal of allergy and clinical immunology : JACI, Vol.144 (2019), No.5, pp.1198-1213
info:doi/10.1016/j.jaci.2019.03.027
Fraunhofer ITEM


Balam, Saidou; Schiechl-Brachner, Gabriela; Buchtler, Simone; Halbritter, Dagmar; Schmidbauer, Kathrin; Talke, Yvonne; Neumayer, Sophia; Salewski, Jan-Niklas; Winter, Frederike; Karasuyama, Hajime; Yamanishi, Yoshinori; Renner, Kerstin; Geissler, Edward K.; Mack, Matthias:
IL-3 triggers chronic rejection of cardiac allografts by activation of infiltrating basophils
The Journal of immunology, Vol.202 (2019), No.12, pp.3514-3523
info:doi/10.4049/jimmunol.1801269
Fraunhofer ITEM


Twisterling, E.S.; Dehmel, S.; Wronski, S.; Braubach, P.; Jonigk, D.D.; Warnecke, G.; Zardo, P.; Krüger, M.; Sewald, K.; Braun, A.:
Immune Response and Airway Hyperresponsiveness to Respiratory Syncytial Virus Are Impaired in Viable Atopic Lung Tissue Ex Vivo of Non-Asthmatic Donors. (American Thoracic Society (ATS International Conference) <2019, Dallas/Tex.>)
American Journal of Respiratory and Critical Care Medicine, Vol.199 (2019), Abstract A2947, 1 pp.
info:doi/10.1164/ajrccm-conference.2019.199.1_MeetingAbstracts.A2947
Fraunhofer ITEM


Chen, S.; Tauber, G.; Langsenlehner, T.; Schmölzer, L.M.; Pötscher, M.; Riethdorf, S.; Kuske, A.; Leitinger, G.; Kashofer, K.; Czyż, Z.T.; Polzer, B.; Pantel, K.; Sedlmayr, P.; Kroneis, T.; El-Heliebi, A.:
In Vivo Detection of Circulating Tumor Cells in High-Risk Non-Metastatic Prostate Cancer Patients Undergoing Radiotherapy
Cancers, Vol.11 (2019), No.7, Art.933
info:doi/10.3390/cancers11070933
Fraunhofer ITEM


Escher, Sylvia E.:
Integration of NAMs in risk assessment: The read-across approach of the EU-ToxRisk project. (Society of Toxicology (Annual Meeting) <58, 2019, Baltimore/Md.>)
The Toxicologist, Vol.168 (2019), No.1, Abstract S 1627
Fraunhofer ITEM


Ravi, A.; Chang, M.; Pol, M.A. van de; Yang, S.; Aliprantis, Antonios; Thornton, Bob; Hohlfeld, Jens M.; Sterk, Peter J.; Krug, Norbert; Lutter, René:
Interferon Response Genes in Nasal Epithelium to Rhinovirus16 Challenge in Asthma Patients Links to Viral Clearance and Common Cold Scores. (American Thoracic Society (ATS International Conference) <2019, Dallas/Tex.>)
American Journal of Respiratory and Critical Care Medicine, Vol.199 (2019), Abstract A1061
info:doi/10.1164/ajrccm-conference.2019.199.1_MeetingAbstracts.A1061
Fraunhofer ITEM


Werner-Klein, Melanie; Grujovic, Ana; Obradović, Milan M.S.; Hoffmann, Martin; Lu, Xin; Kirsch, Stefan; Treitschke, Steffi; Köstler, Cäcilia; Weidele, Kathrin; Irlbeck, Christoph; Botteron, Cathrine; Werno, Christian; Polzer, Bernhard; Guzvic, Miodrag; Buchholz, Stefan; Rümmele, Petra; Heine, Norbert; Rose-John, Stefan; Klein, Christoph A.:
Interleukin 6 transsignaling is a candidate mechanism to drive progression of human DCCs during periods of clinical latency. (American Association for Cancer Research (AACR Annual Meeting) <2019, Atlanta/Ga.>)
Cancer research, Vol.79 (2019), No.13, Supplement, Abstract LB-312
info:doi/10.1158/1538-7445.AM2019-LB-312
Fraunhofer ITEM


Blazquez, Raquel; Rietkötter, Eva; Wenske, Britta; Wlochowitz, Darius; Sparrer, Daniela; Vollmer, Elena; Müller, Gunnar; Seegerer, Julia; Sun, Xueni; Dettmer, Katja; Barrantes-Freer, Alonso; Stange, Lena; Utpatel, Kirsten; Bleckmann, Annalen; Treiber, Hannes; Bohnenberger, Hanibal; Lenz, Christof; Schulz, Matthias; Reimelt, Christian; Hackl, Christina; Grade, Marian; Büyüktas, Deram; Siam, Laila; Balkenhol, Marko; Stadelmann, Christine; Kube, Dieter; Krahn, Michael P.; Proescholdt, Martin A.; Riemenschneider, Markus J.; Evert, Matthias; Oefner, Peter J.; Klein, Christoph A.; Hanisch, Uwe K.; Binder, Claudia; Pukrop, Tobias:
LEF1 supports metastatic brain colonization by regulating glutathione metabolism and increasing ROS resistance in breast cancer
International journal of cancer, (2019), Online First, 14 pp.
urn:nbn:de:0011-n-5746684
info:doi/10.1002/ijc.32742
Volltext
Fraunhofer ITEM


Struß, Nadja; Bauersachs, Johann; Welte, Tobias; Hohlfeld, Jens M.:
Left heart function in COPD: Impact of lung deflation
Herz, Vol.44 (2019), No.6, pp.477-482
info:doi/10.1007/s00059-019-4816-5
Fraunhofer ITEM


Kenneweg, Franziska; Bang, Claudia; Xiao, Ke; Boulanger, Chantal M.; Loyer, Xavier; Mazlan, Stephane; Schroen, Blanche; Hermans-Beijnsberger, Steffie; Foinquinos, Ariana; Hirt, Marc N.; Eschenhagen, Thomas; Funcke, Sandra; Stojanovic, Stevan; Genschel, Celina; Schimmel, Katharina; Just, Annette; Pfanne, Angelika; Scherf, Kristian; Dehmel, Susann; Reamon-Buettner, Stella Marie; Fiedler, Jan; Thum, Thomas:
Long noncoding RNA-enriched vesicles secreted by hypoxic cardiomyocytes drive cardiac fibrosis
Molecular therapy. Nucleic Acids, Vol.18 (2019), pp.363-374
urn:nbn:de:0011-n-5660578
info:doi/10.1016/j.omtn.2019.09.003
Volltext
Fraunhofer ITEM


Landsiedel, R.; Ma-Hock, L.; Wiench, K.; Groeters, S.; Ravenzwaay, B. van; Ernst, H.; Schaudien, D.:
Long-term effects of inhaled nanoparticles in rats - ceriumdioxide and bariumsulfate. (European Societies of Toxicology (EUROTOX Congress) <55, 2019, Helsinki>)
Toxicology letters, Vol.314 (2019), Supplement, pp.S64-S65
Fraunhofer ITEM


Ma-Hock, L.; Wiench, K.; Groeters, S.; Ravenzwaay, B. van; Landsiedel, R.; Ernst, H.; Schaudien, D.:
Long-term effects of inhaled nanoparticles in rats - Ceriumdioxide and Bariumsulphate. (German Society for Experimental and Clinical Pharmacology and Toxicology (DGPT Annual Meeting) <85, 2019, Stuttgart>)
Naunyn-Schmiedebergs archives of pharmacology, Vol.392 (2019), Supplement 1, pp.S20
Fraunhofer ITEM


Landsiedel, R.; Ma-Hock, Lan; Wiench, K.; Gröters, S.; Ravenzwaay, Bennard van; Ernst, Heinrich; Schaudien, Dirk:
Long-term effects of inhaled nanoparticles in rats: Ceriumdioxide and bariumsulphate. (Society of Toxicology (Annual Meeting) <58, 2019, Baltimore/Md.>)
The Toxicologist, Vol.168 (2019), No.1, Abstract PS 2217
Fraunhofer ITEM


Kern, A.L.; Gutberlet, M.; Voskrebenzev, A.; Klimes, F.; Rotärmel, A.; Wacker, F.; Hohlfeld, J.M.; Vogel-Claussen, J.:
Mapping of regional lung microstructural parameters using hyperpolarized 129Xe dissolved‐phase MRI in healthy volunteers and patients with chronic obstructive pulmonary disease
Magnetic resonance in medicine, Vol.81 (2019), No.4, pp.2360-2373
info:doi/10.1002/mrm.27559
Fraunhofer ITEM


Stassen, M.; Hartmann, A.K.; Delgado, S.J.; Dehmel, S.; Braun, A.:
Mast cells within cellular networks
The journal of allergy and clinical immunology : JACI, Vol.144 (2019), No.4, pp.S46-S54
info:doi/10.1016/j.jaci.2019.01.031
Fraunhofer ITEM


Sonnenschein, Nico; Walker, Gottfrid (1. Prüfer); Hansen, Tanja (2. Prüfer) :
Messung der Permeabilitätskoeffizienten bei dem inhalierbaren Antibiotikum Ciprofloxacin HCl Monohydrat
Emden-Leer, Hochschule, Master Thesis, 2019
Fraunhofer ITEM


Weidele, Kathrin; Stojanović, Nataša; Feliciello, Giancarlo; Markiewicz, Aleksandra; Scheitler, Sebastian; Alberter, Barbara; Renner, Philipp; Haferkamp, Sebastian; Klein, Christoph A.; Polzer, Bernhard:
Microfluidic enrichment, isolation and characterization of disseminated melanoma cells from lymph node samples
International journal of cancer, Vol.145 (2019), No.1, pp.232-241
info:doi/10.1002/ijc.32092
Fraunhofer ITEM


Bahudhanapati, H.; Tan, J.; Dutta, J.A.; Strock, S.B.; Sembrat, J.; Alvarez, D.; Rojas, M.; Jäger, B.; Prasse, A.; Zhang, Y.; Kass, D.J.:
MicroRNA-144-3p targets relaxin/insulin-like family peptide receptor 1 (RXFP1) expression in lung fibroblasts from patients with idiopathic pulmonary fibrosis
The Journal of biological chemistry, Vol.294 (2019), No.13, pp.5008-5022
info:doi/10.1074/jbc.RA118.004910
Fraunhofer ITEM


Heissig, F.; Litzenburger, T.; Müller, Meike; Wetzel, Kristiane; Hohl, Kathrin; Schmid, Rolf; Seibold, Wolfgang; Sarno, Maria; Gupta, A.; Badorrek, Philipp; Faulenbach, Cornelia; Hohlfeld, Jens M.:
Molecular Characterization of a Human LPS Challenge Model. (American Thoracic Society (ATS International Conference) <2019, Dallas/Tex.>)
American Journal of Respiratory and Critical Care Medicine, Vol.199 (2019), Abstract A4534
info:doi/10.1164/ajrccm-conference.2019.199.1_MeetingAbstracts.A4534
Fraunhofer ITEM


Jensen, L.R.; Garrett, L.; Hölter, S.M.; Rathkolb, B.; Rácz, I.; Adler, T.; Prehn, C.; Hans, W.; Rozman, J.; Becker, L.; Aguilar-Pimentel, J.A.; Puk, O.; Moreth, K.; Dopatka, M.; Walther, D.J.; Bohlen und Halbach, V. von; Rath, M.; Delatycki, M.; Bert, B.; Fink, H.; Blümlein, K.; Ralser, M.; Dijck, A. van; Kooy, F.; Stark, Z.; Müller, S.; Scherthan, H.; Gecz, J.; Wurst, W.; Wolf, E.; Zimmer, A.; Klingenspor, M.; Graw, J.; Klopstock, T.; Busch, D.; Adamski, J.; Fuchs, H.; Gailus-Durner, V.; Hrabě de Angelis, M.; Bohlen und Halbach, O. von; Ropers, H.-H.; Kuss, A.W.:
A mouse model for intellectual disability caused by mutations in the X-linked 2'‑O‑methyltransferase Ftsj1 gene
Biochimica et biophysica acta. Molecular basis of disease, Vol.1865 (2019), No.9, pp.2083-2093
info:doi/10.1016/j.bbadis.2018.12.011
Fraunhofer ITEM


Campos-Sanchez, E.; Vicente‐Dueñas, C.; Rodríguez‐Hernández, G.; Capstick, M.; Kuster, N.; Dasenbrock, C.; Sánchez-García, I.; Cobaleda, C.:
Novel ETV6‐RUNX1 Mouse Model to Study the Role of ELF‐MF in Childhood B‐Acute Lymphoblastic Leukemia: A Pilot Study
Bioelectromagnetics, Vol.40 (2019), No.5, pp.343-353
info:doi/10.1002/bem.22193
Fraunhofer ITEM


Czyz, Zbigniew T.; Feliciello, Giancarlo; Guzvic, Miodrag; Schamberger, Thomas; Grunewald, Sandra; Corbacioglu, Selim; Riemenschneider, Markus J.; Polzer, Bernhard; Klein, Christoph A.:
A novel workflow for isolation and multi-omic profiling of DCCs derived from cerebrospinal fluid of patients with pediatric brain cancer. (American Association for Cancer Research (AACR Annual Meeting) <2019, Atlanta/Ga.>)
Cancer research, Vol.79 (2019), No.13, Supplement, Abstract LB-239
info:doi/10.1158/1538-7445.AM2019-LB-239
Fraunhofer ITEM


Paul, R.; Gerling, S.; Berger, M.; Blümlein, K.; Jäckel, U.; Schuchardt, S.:
Occupational Exposure to Antibiotics in Poultry Feeding Farms
Annals of work exposures and health, Vol.63 (2019), No.7, pp.821-827
info:doi/10.1093/annweh/wxz047
Fraunhofer ITEM


Biermann, Niklas; Geissler, Edward K.; Brix, Eva; Schiltz, Daniel; Prantl, Lukas; Kehrer, Andreas; Taeger, Christian D.:
Oxygen levels during negative pressure wound therapy
Journal of tissue viability, Vol.28 (2019), No.4, pp.223-226
info:doi/10.1016/j.jtv.2019.09.001
Fraunhofer ITEM


Graepel, R.; Ter Braak, B.; Escher, S.E.; Fisher, C.; Gardner, I.; Kamp, H.; Kroese, D.; Leist, M.; Moné, M.J.; Pastor, M.; Water, B. van de:
Paradigm shift in safety assessment using new approach methods: The EU-ToxRisk strategy
Current opinion in toxicology, Vol.15 (2019), pp.33-39
info:doi/10.1016/j.cotox.2019.03.005
Fraunhofer ITEM


Prasse, A.:
POINT: Should Molecular and Genetic Biomarkers Be Used in the Initial Evaluation of Patients With Fibrotic ILD? Yes
Chest, Vol.156 (2019), No.2, pp.203-205
info:doi/10.1016/j.chest.2019.03.026
Fraunhofer ITEM


Mycielska, M.E.; Mohr, M.T.J.; Schmidt, K.; Drexler, K.; Rümmele, P.; Haferkamp, S.; Schlitt, H.J.; Gaumann, A.; Adamski, J.; Geissler, E.K.:
Potential use of gluconate in cancer therapy
Frontiers in oncology, Vol.9 (2019), Art. 522, 7 pp.
urn:nbn:de:0011-n-5828153
info:doi/10.3389/fonc.2019.00522
Volltext
Fraunhofer ITEM


Afrapoli, F.M.; Wehr, M.; Bitsch, A.; Escher, S.E.:
Prediction of adverse effects in preclinical subchronic studies by analysis of adverse effects from shorter-term studies using e.g. the RepDose database. (European Societies of Toxicology (EUROTOX Congress) <55, 2019, Helsinki>)
Toxicology letters, Vol.314 (2019), Supplement, pp.S261
Fraunhofer ITEM


Pavan, C.; Delle Piane, M.; Gullo, M.; Filippi, F.; Fubini, B.; Hoet, P.; Horwell, C.J.; Huaux, F.; Lison, D.; Lo Giudice, C.; Martra, G.; Montfort, E.; Schins, R.; Sulpizi, M.; Wegner, K.; Wyart-Remy, M.; Ziemann, C.; Turci, F.:
The puzzling issue of silica toxicity: are silanols bridging the gaps between surface states and pathogenicity?
Particle and Fibre Toxicology, Vol.16 (2019), Art.32, 10 pp.
info:doi/10.1186/s12989-019-0315-3
Fraunhofer ITEM


Wagenmann, M.; Worm, M.; Akboga, Y.; Karjalainen, M.; Hohlfeld, J.M.:
Randomized immunotherapy trial in dual‐allergic patients using "active allergen placebo" as control
Allergy. European journal of allergy and clinical immunology, Vol.74 (2019), No.8, pp.1480-1489
info:doi/10.1111/all.13842
Fraunhofer ITEM


Buchholz, B.M.; Ferguson, J.W.; Schnitzbauer, A.A.; Nightingale, P.; Schlitt, H.J.; Geissler, E.K.; Mirza, D.F.:
Randomized Sirolimus-based early calcineurin inhibitor reduction in liver transplantation: Impact on renal function
Transplantation, (2019), Online First
info:doi/10.1097/TP.0000000000002980
Fraunhofer ITEM


Igl, Bernd-Wolfgang; Bitsch, Annette; Bringezu, Frank; Chang, Steffi; Dammann, Martina; Frötschl, Roland; Harm, Volker; Kellner, Rupert; Krzykalla, Volker; Lott, Jasmin; Nern, Marlies; Pfuhler, Stefan; Queisser, Nina; Schulz, Markus; Sutter, Andreas; Vaas, Lea; Vonk, Richardus; Zellner, Dietmar; Ziemann, Christina:
The rat bone marrow micronucleus test: Statistical considerations on historical negative control data
Regulatory toxicology and pharmacology, Vol.102 (2019), pp.13-22
info:doi/10.1016/j.yrtph.2018.12.009
Fraunhofer ITEM


Pedersen, Frauke; Zissler, Ulrich M.; Watz, Henrik; Rabe, Klaus F.; Hohlfeld, Jens M.; Holz, Olaf:
Rating sputum cell quality in clinical trials for asthma and COPD treatment
International journal of chronic obstructive pulmonary disease, Vol.14 (2019), pp.195-198
info:doi/10.2147/COPD.S188033
Fraunhofer ITEM


Escher, S.E.:
Read-across concept in EU-ToxRisk and integration of new approach methods into risk assessment - example branched carboxylic acids. (European Societies of Toxicology (EUROTOX Congress) <55, 2019, Helsinki>)
Toxicology letters, Vol.314 (2019), Supplement, pp.S27
Fraunhofer ITEM


Kühne, Britta; Ritter, Detlef; Knebel, Jan; Boei, J.; Vrieling, H.; Hiemstra, P.; Escher, Sylvia E.; Hansen, Tanja:
A read-across study on diketones. (Society of Toxicology (Annual Meeting) <58, 2019, Baltimore/Md.>)
The Toxicologist, Vol.168 (2019), No.1, Abstract PS 2029
Fraunhofer ITEM


Prasse, A.:
Rebuttal From Dr Prasse
Chest, Vol.156 (2019), No.2, pp.208-209
info:doi/10.1016/j.chest.2019.03.029
Fraunhofer ITEM


Kern, A.L.; Gutberlet, M.; Qing, K.; Voskrebenzev, A.; Klimes, F.; Kaireit, T.F.; Czerner, C.; Biller, H.; Wacker, F.; Ruppert, K.; Hohlfeld, J.M.; Vogel-Claussen, J.:
Regional investigation of lung function and microstructure parameters by localized 129Xe chemical shift saturation recovery and dissolved‐phase imaging: A reproducibility study
Magnetic resonance in medicine, Vol.81 (2019), No.1, pp.13-24
info:doi/10.1002/mrm.27407
Fraunhofer ITEM


Gutberlet, M.; Kaireit, T.F.; Voskrebenzev, A.; Kern, A.L.; Obert, A.; Wacker, F.; Hohlfeld, J.M.; Vogel-Claussen, J.:
Repeatability of Regional Lung Ventilation Quantification Using Fluorinated (19F) Gas Magnetic Resonance Imaging
Academic radiology, Vol.26 (2019), No.3, pp.395-403
info:doi/10.1016/j.acra.2018.10.021
Fraunhofer ITEM


Almeida, L.; Dhillon-LaBrooy, A.; Castro, C.N.; Ayele, N.; Bartel, J.; Carriche, G.M.; Guderian, M.; Lippens, S.; Dennerlein, S.; Hesse, Christina; Lambrecht, Bart N.; Schauser, L.; Blazar, B.R.; Kalesse, Markus; Müller, R.; Moita, L.F.; Sparwasser, T.:
Ribosome-targeting antibiotics impair T cell effector function and ameliorate autoimmunity by blocking mitochondrial protein synthesis
bioRxiv. The preprint server for biology. Online resource, (2019), 40 pp.
urn:nbn:de:0011-n-5746704
info:doi/10.1101/832956
Volltext
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 1,2-dimethoxybenzene, CAS Registry Number 91-16-7
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110618
info:doi/10.1016/j.fct.2019.110618
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 1,2-dimethoxybenzene, CAS Registry Number 91-16-7
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110618
info:doi/10.1016/j.fct.2019.110618
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 1,4-dimethoxy-2-tert-butylbenzene, CAS Registry Number 21112-37-8
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110459
info:doi/10.1016/j.fct.2019.04.029
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 1,5-dimethylhexyl acetate, CAS Registry Number 67952-57-2
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110625
info:doi/10.1016/j.fct.2019.110625
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 1,6-heptadien-3-one, 2-cyclohexyl-, CAS Registry Number 313973-37-4
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110451
info:doi/10.1016/j.fct.2019.04.021
Fraunhofer ITEM


Api, A.M.; Belmonte, F.; Belsito, D.; Biserta, S.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Cancellieri, M.A.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Gadhia, S.; Jones, L.; Joshi, K.; Lapczynski, A.; Lavelle, M.; Liebler, D.C.; Na, M.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Rodriguez-Ropero, F.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 1-(2,4,4,5,5-pentamethyl-1-cyclopenten-1-yl)ethan-1-one, CAS Registry Number 13144-88-2
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110637
info:doi/10.1016/j.fct.2019.110637
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 1-cyclohexene-1-acetic acid, CAS Registry Number 18294-87-6
Food and Chemical Toxicology : FCT, Vol.127 (2019), Supplement 1, pp.S132-S137
info:doi/10.1016/j.fct.2019.03.011
Fraunhofer ITEM


Api, A.M.; Belmonte, F.; Belsito, D.; Biserta, S.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Cancellieri, M.A.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Gadhia, S.; Jones, L.; Joshi, K.; Lapczynski, A.; Lavelle, M.; Liebler, D.C.; Na, M.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Rodriguez-Ropero, F.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 1-octen-3-yl acetate, CAS Registry Number 2442-10-6
Food and Chemical Toxicology : FCT, Vol.134 (2019), Supplement 1, Art. 110638
info:doi/10.1016/j.fct.2019.110638
Fraunhofer ITEM


Api, A.M.; Belmonte, F.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Gadhia, S.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Lavelle, M.; Liebler, D.C.; Na, M.; O'Brien, D.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 2,2,3-trimethylcyclopent-3-enylacetonitrile, CAS Registry Number 15373-31-6
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110571
info:doi/10.1016/j.fct.2019.110571
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 2,4-dimethyl-4,4a,5,9b-tetrahydroindeno[1,2-d]-1,3-dioxin, CAS Registry Number 27606-09-3
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110568
info:doi/10.1016/j.fct.2019.110568
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A., Jr.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, [2-(cyclohexyloxy)ethyl]benzene, CAS Registry Number 80858-47-5
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110636
info:doi/10.1016/j.fct.2019.110636
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 2-ethyl-5-methoxybicyclo[2.2.1]heptane, CAS registry number 122795-41-9
Food and Chemical Toxicology : FCT, Vol.127 (2019), Supplement 1, pp.S90-S99
info:doi/10.1016/j.fct.2019.01.031
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 2-ethylbutyl acetate, CAS Registry Number 10031-87-5
Food and Chemical Toxicology : FCT, Vol.127 (2019), Supplement 1, pp.S23-S30
info:doi/10.1016/j.fct.2018.12.007
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 2-heptanone, CAS Registry Number 110-43-0
Food and Chemical Toxicology : FCT, Vol.134 (2019), Supplement 1, Art. 110627
info:doi/10.1016/j.fct.2019.110627
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 2-isobutyl-4-methyltetrahydro-2H-pyran-4-ol, CAS registry number 63500-71-0
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110564
info:doi/10.1016/j.fct.2019.110564
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 2-isopropyl-5-methylcyclohexyl 2-methylbut-2-enoate, CAS Registry Number 67801-23-4
Food and Chemical Toxicology : FCT, Vol.134 (2019), Supplement 1, Art. 110623
info:doi/10.1016/j.fct.2019.110623
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
Rifm fragrance ingredient safety assessment, 2-methylpentyl 2-methylvalerate, CAS Registry Number 90397-38-9
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110457
info:doi/10.1016/j.fct.2019.04.027
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 2-octanone, CAS Registry Number 111-13-7
Food and Chemical Toxicology : FCT, Vol.127 (2019), Supplement 1, pp.S71-S80
info:doi/10.1016/j.fct.2019.01.029
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 2-phenoxyethanol, CAS Registry Number 122-99-6
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110629
info:doi/10.1016/j.fct.2019.110629
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 2-tert-butylcyclohexyl propionate, CAS Registry Number 40702-13-4
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110630
info:doi/10.1016/j.fct.2019.110630
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 2-undecanone, CAS Registry Number 112-12-9
Food and Chemical Toxicology : FCT, Vol.134 (2019), Supplement 1, Art. 110634
info:doi/10.1016/j.fct.2019.110634
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 3,5-dimethoxytoluene, CAS Registry Number 4179-19-5
Food and Chemical Toxicology : FCT, Vol.134 (2019), Supplement 1, Art. 110617
info:doi/10.1016/j.fct.2019.110617
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 3,7-dimethyl-6-octenoic acid, CAS Registry Number 502-47-6
Food and Chemical Toxicology : FCT, Vol.127 (2019), Supplement 1, pp.S107-S113
info:doi/10.1016/j.fct.2018.11.064
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 3,7-dimethyloctanenitrile, CAS Registry Number 40188-41-8
Food and Chemical Toxicology : FCT, Vol.127 (2019), Supplement 1, pp.S63-S70
info:doi/10.1016/j.fct.2019.01.024
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 3-(4-methylcyclohex-3-enyl)-3-butenyl acetate, CAS Registry Number 6819-19-8
Food and Chemical Toxicology : FCT, Vol.127 (2019), Supplement 1, pp.S100-S106
info:doi/10.1016/j.fct.2018.11.063
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 3-heptanone, CAS Registry Number 106-35-4
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110452
info:doi/10.1016/j.fct.2019.04.022
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 3-hexanone, CAS Registry Number 589-38-8
Food and Chemical Toxicology : FCT, Vol.134 (2019), Supplement 1, Art. 110628
info:doi/10.1016/j.fct.2019.110628
Fraunhofer ITEM


Api, A.M.; Belmonte, F.; Belsito, D.; Biserta, S.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Cancellieri, M.A.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Gadhia, S.; Jones, L.; Joshi, K.; Lapczynski, A.; Lavelle, M.; Liebler, D.C.; Na, M.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Rodriguez-Ropero, F.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 3-methyl-2-(pentyloxy)cyclopent-2-en-1-one, CAS Registry Number 68922-13-4
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110639
info:doi/10.1016/j.fct.2019.110639
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 3-methyldodecanonitrile, CAS Registry Number 85351-07-1
Food and Chemical Toxicology : FCT, Vol.127 (2019), Supplement 1, pp.S114-S122
info:doi/10.1016/j.fct.2019.03.009
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 3-methylpentyl 2-methylisocrotonate, CAS Registry Number 53082-58-9
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110633
info:doi/10.1016/j.fct.2019.110633
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 3-phenylpropionic acid, CAS Registry Number 501-52-0
Food and Chemical Toxicology : FCT, Vol.134 (2019), Supplement 1, Art. 110601
info:doi/10.1016/j.fct.2019.110601
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 3a,4,5,6,7,7a-hexahydro-5-methoxy-4,7-methano-1H-indene, CAS Registry Number 53018-24-9
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110454
info:doi/10.1016/j.fct.2019.04.024
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Biserta, S.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Cancellieri, M.A.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Gadhia, S.; Jones, L.; Joshi, K.; Lapczynski, A.; Lavelle, M.; Liebler, D.C.; Na, M.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Rodriguez-Ropero, F.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Siddiqi, F.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 4,8-dimethyl-4,9-decadienal, CAS Registry Number 71077-31-1
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110648
info:doi/10.1016/j.fct.2019.110648
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM Fragrance ingredient safety assessment, 4-cyclohexyl-2-methyl-2-butanol, CAS Registry Number 83926-73-2
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110609
info:doi/10.1016/j.fct.2019.110609
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 4-ethyloctanoic acid, CAS Registry Number 16493-80-4
Food and Chemical Toxicology : FCT, Vol.127 (2019), Supplement 1, pp.S208-S215
info:doi/10.1016/j.fct.2019.03.022
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 4-heptanol, 2,6-dimethyl-,acetate, CAS Registry Number 10250-45-0
Food and Chemical Toxicology : FCT, Vol.134 (2019), Supplement 1, Art. 110603
info:doi/10.1016/j.fct.2019.110603
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 4-heptanone, CAS Registry Number 123-19-3
Food and Chemical Toxicology : FCT, Vol.127 (2019), Supplement 1, pp.S31-S39
info:doi/10.1016/j.fct.2018.12.048
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 4-methyl-2-pentanone, CAS Registry Number 108-10-1
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110587
info:doi/10.1016/j.fct.2019.110587
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 4-methyloctanoic acid, CAS Registry Number 54947-74-9
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110569
info:doi/10.1016/j.fct.2019.110569
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 4H-4a,9-methanoazuleno[5,6-d]-1,3-dioxole, octahydro-2,2,5,8,8,9a-hexamethyl-, (4aR,5R,7aS,9R)-, CAS Registry Number 211299-54-6
Food and Chemical Toxicology : FCT, Vol.127 (2019), Supplement 1, pp.S224-S230
info:doi/10.1016/j.fct.2019.03.024
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 5-hexen-2-one, CAS Registry Number 109-49-9
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110589
info:doi/10.1016/j.fct.2019.110589
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Biserta, S.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Cancellieri, M.A.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Gadhia, S.; Jones, L.; Joshi, K.; Lapczynski, A.; Lavelle, M.; Liebler, D.C.; Na, M.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Rodriguez-Ropero, F.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Siddiqi, F.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, α-amylcinnamyl alcohol, CAS Registry Number 101-85-9
Food and Chemical Toxicology : FCT, Vol.134 (2019), Supplement 1, Art. 110712
info:doi/10.1016/j.fct.2019.110712
Fraunhofer ITEM


Api, A.M.; Belmonte, F.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Gadhia, S.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Lavelle, M.; Liebler, D.C.; Na, M.; O'Brien, D.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, amyl hexanoate, CAS Registry Number 540-07-8
Food and Chemical Toxicology : FCT, Vol.134 (2019), Supplement 1, Art. 110621
info:doi/10.1016/j.fct.2019.110621
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, anisyl phenylacetate, CAS Registry Number 102-17-0
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110626
info:doi/10.1016/j.fct.2019.110626
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Biserta, S.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Cancellieri, M.A.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Gadhia, S.; Jones, L.; Joshi, K.; Lapczynski, A.; Lavelle, M.; Liebler, D.C.; Na, M.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Rodriguez-Ropero, F.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Siddiqi, F.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, β,β,3-trimethyl benzenepropanol, CAS Registry Number 103694-68-4
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110650
info:doi/10.1016/j.fct.2019.110650
Fraunhofer ITEM


Api, A.M.; Belmonte, F.; Belsito, D.; Biserta, S.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Cancellieri, M.A.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Gadhia, S.; Jones, L.; Joshi, K.; Lapczynski, A.; Lavelle, M.; Liebler, D.C.; Na, M.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Rodriguez-Ropero, F.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, bicyclo[3.1.0]hexan-3-one, 4-methyl-1-(1-methylethyl)-, CAS Registry Number 1125-12-8
Food and Chemical Toxicology : FCT, Vol.134 (2019), Supplement 1, Art. 110724
info:doi/10.1016/j.fct.2019.110724
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, butyl 10-undecenoate, CAS Registry Number 109-42-2
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110619
info:doi/10.1016/j.fct.2019.110619
Fraunhofer ITEM


Api, A.M.; Belmonte, F.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Gadhia, S.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Lavelle, M.; Liebler, D.C.; Na, M.; O'Brien, D.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, butyl sulfide, CAS Registry Number 544-40-1
Food and Chemical Toxicology : FCT, Vol.134 (2019), Supplement 1, Art. 110606
info:doi/10.1016/j.fct.2019.110606
Fraunhofer ITEM


Api, A.M.; Belmonte, F.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Gadhia, S.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Lavelle, M.; Liebler, D.C.; Na, M.; O'Brien, D.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, butyric acid, CAS Registry Number 107-92-6
Food and Chemical Toxicology : FCT, Vol.127 (2019), Supplement 1, pp.S81-S89
info:doi/10.1016/j.fct.2019.01.030
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM Fragrance ingredient safety assessment, cis-3-hexenyl anthranilate, CAS Registry Number 65405-76-7
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110611
info:doi/10.1016/j.fct.2019.110611
Fraunhofer ITEM


Api, A.M.; Belmonte, F.; Belsito, D.; Biserta, S.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Cancellieri, M.A.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Gadhia, S.; Jones, L.; Joshi, K.; Lapczynski, A.; Lavelle, M.; Liebler, D.C.; Na, M.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Rodriguez-Ropero, F.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, coumarin, CAS Registry Number 91-64-5
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110522
info:doi/10.1016/j.fct.2019.05.030
Fraunhofer ITEM


Api, A.M.; Belmonte, F.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Gadhia, S.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Lavelle, M.; Liebler, D.C.; Na, M.; O'Brien, D.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, cyclohexanol,4-(3-methylbutyl)-, CAS Registry Number 830322-14-0
Food and Chemical Toxicology : FCT, Vol.127 (2019), Supplement 1, pp.S1-S9
info:doi/10.1016/j.fct.2018.11.051
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, cyclohexanone, 2-ethyl-4,4-dimethyl-, CAS Registry Number 55739-89-4
Food and Chemical Toxicology : FCT, Vol.134 (2019), Supplement 1, Art. 110604
info:doi/10.1016/j.fct.2019.110604
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, cyclohexyl acetate, CAS Registry Number 622-45-7
Food and Chemical Toxicology : FCT, Vol.127 (2019), Supplement 1, pp.S123-S131
info:doi/10.1016/j.fct.2019.03.010
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, cyclohexyl butyrate, CAS Registry Number 1551-44-6
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110566
info:doi/10.1016/j.fct.2019.110566
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, cyclopentanol, 2-(2-hexen-1-yl)-, CAS Registry Number 34686-67-4
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110536
info:doi/10.1016/j.fct.2019.05.044
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, decyl acetate, CAS Registry Number 112-17-4
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110456
info:doi/10.1016/j.fct.2019.04.026
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, diphenyl ether, CAS Registry Number 101-84-8
Food and Chemical Toxicology : FCT, Vol.134 (2019), Supplement 1, Art. 110632
info:doi/10.1016/j.fct.2019.110632
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, ethyl 2,4-dimethyldioxolane-2-acetate, CAS Registry Number 6290-17-1
Food and Chemical Toxicology : FCT, Vol.134 (2019), Supplement 1, Art. 110590
info:doi/10.1016/j.fct.2019.110590
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, ethyl 2-hexylacetoacetate, CAS Registry Number 29214-60-6
Food and Chemical Toxicology : FCT, Vol.127 (2019), Supplement 1, pp.S159-S164
info:doi/10.1016/j.fct.2019.03.015
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, ethyl 2-methoxybenzyl ether, CAS Registry Number 64988-06-3
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110613
info:doi/10.1016/j.fct.2019.110613
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, ethyl 3-phenylpropionate, CAS Registry Number 2021-28-5
Food and Chemical Toxicology : FCT, Vol.127 (2019), Supplement 1, pp.S179-S186
info:doi/10.1016/j.fct.2019.03.018
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, ethyl acetoacetate, CAS Registry Number 141-97-9
Food and Chemical Toxicology : FCT, Vol.127 (2019), Supplement 1, pp.S165-S171
info:doi/10.1016/j.fct.2019.03.016
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, ethyl benzoate, CAS Registry Number 93-89-0
Food and Chemical Toxicology : FCT, Vol.127 (2019), Supplement 1, pp.S172-S178
info:doi/10.1016/j.fct.2019.03.017
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, ethyl levulinate, CAS Registry Number 539-88-8
Food and Chemical Toxicology : FCT, Vol.127 (2019), Supplement 1, pp.S48-S54
info:doi/10.1016/j.fct.2018.12.050
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, hexyl butyrate, CAS Registry Number 2639-63-6
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110608
info:doi/10.1016/j.fct.2019.110608
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, isoamyl phenylacetate, CAS Registry Number 102-19-2
Food and Chemical Toxicology : FCT, Vol.127 (2019), Supplement 1, pp.S40-S47
info:doi/10.1016/j.fct.2018.12.049
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, isobutyl acetate, CAS Registry Number 110-19-0
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110488
info:doi/10.1016/j.fct.2019.04.058
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, isobutyl hexanoate, CAS Registry Number 105-79-3
Food and Chemical Toxicology : FCT, Vol.127 (2019), Supplement 1, pp.S152-S158
info:doi/10.1016/j.fct.2019.03.014
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, isobutyl propionate, CAS Registry Number 540-42-1
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110607
info:doi/10.1016/j.fct.2019.110607
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, isopropyl acetate, CAS Registry Number 108-21-4
Food and Chemical Toxicology : FCT, Vol.127 (2019), Supplement 1, pp.S187-S192
info:doi/10.1016/j.fct.2019.03.019
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, isopropyl butyrate CAS Registry Number 638-11-9
Food and Chemical Toxicology : FCT, Vol.127 (2019), Supplement 1, pp.S10-S16
info:doi/10.1016/j.fct.2018.11.058
Fraunhofer ITEM


Api, A.M.; Belmonte, F.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Gadhia, S.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Lavelle, M.; Liebler, D.C.; Na, M.; O'Brien, D.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, isovaleric acid, CAS Registry Number 503-74-2
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110570
info:doi/10.1016/j.fct.2019.110570
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, lactoscatone, CAS Registry Number 21280-29-5
Food and Chemical Toxicology : FCT, Vol.127 (2019), Supplement 1, pp.S55-S62
info:doi/10.1016/j.fct.2019.01.022
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, linalyl anthranilate, CAS Registry Number 7149-26-0
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110610
info:doi/10.1016/j.fct.2019.110610
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, m-dimethoxybenzene, CAS Registry Number 151-10-0
Food and Chemical Toxicology : FCT, Vol.127 (2019), Supplement 1, pp.S145-S151
info:doi/10.1016/j.fct.2019.03.013
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, methyl 2-methylbutyrate, CAS Registry Number 868-57-5
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110614
info:doi/10.1016/j.fct.2019.110614
Fraunhofer ITEM


Api, A.M.; Belmonte, F.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Gadhia, S.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Lavelle, M.; Liebler, D.C.; Na, M.; O'Brien, D.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, methyl 2-nonenoate, CAS Registry Number 111-79-5
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110622
info:doi/10.1016/j.fct.2019.110622
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, methyl 3,7-dimethyl-6-octenoate, CAS Registry Number 2270-60-2
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110616
info:doi/10.1016/j.fct.2019.110616
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, methyl acetoacetate, CAS Registry Number 105-45-3
Food and Chemical Toxicology : FCT, Vol.134 (2019), Supplement 1, Art. 110615
info:doi/10.1016/j.fct.2019.110615
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, methyl undec-10-enoate, CAS Registry Number 111-81-9
Food and Chemical Toxicology : FCT, Vol.127 (2019), Supplement 1, pp.S17-S22
info:doi/10.1016/j.fct.2018.11.059
Fraunhofer ITEM


Api, A.M.; Belmonte, F.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Gadhia, S.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Lavelle, M.; Liebler, D.C.; Na, M.; O'Brien, D.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, myristic acid, CAS Registry Number 544-63-8
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110460
info:doi/10.1016/j.fct.2019.04.030
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, myrtenol, CAS Registry Number 515-00-4
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110602
info:doi/10.1016/j.fct.2019.110602
Fraunhofer ITEM


Api, A.M.; Belmonte, F.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Gadhia, S.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Lavelle, M.; Liebler, D.C.; Na, M.; O'Brien, D.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, octyl crotonate, CAS Registry Number 22874-79-9
Food and Chemical Toxicology : FCT, Vol.127 (2019), Supplement 1, pp.S138-S144
info:doi/10.1016/j.fct.2019.03.012
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, p-dimethoxybenzene, CAS Registry Number 150-78-7
Food and Chemical Toxicology : FCT, Vol.127 (2019), Supplement 1, pp.S193-S199
info:doi/10.1016/j.fct.2019.03.020
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, p-isopropylacetophenone, CAS Registry Number 645-13-6
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110565
info:doi/10.1016/j.fct.2019.110565
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, p-menth-8-en-2-one, CAS Registry Number 7764-50-3
Food and Chemical Toxicology : FCT, Vol.127 (2019), Supplement 1, pp.S200-S207
info:doi/10.1016/j.fct.2019.03.021
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, p-tolyl 3-methylcrotonate, CAS Registry Number 24700-20-7
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110567
info:doi/10.1016/j.fct.2019.110567
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, propanal diethyl acetal, CAS registry number 4744-08-5
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110588
info:doi/10.1016/j.fct.2019.110588
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, propionic acid, CAS Registry Number 79-09-4
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110635
info:doi/10.1016/j.fct.2019.110635
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, spiro[5.5]undec-8-en-1-one, 2,2,7,9-tetramethyl-, CAS Registry Number 502847-01-0
Food and Chemical Toxicology : FCT, Vol.130 (2019), Supplement 1, Art.110458
info:doi/10.1016/j.fct.2019.04.028
Fraunhofer ITEM


Api, A.M.; Belmonte, F.; Belsito, D.; Biserta, S.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Cancellieri, M.A.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Gadhia, S.; Jones, L.; Joshi, K.; Lapczynski, A.; Lavelle, M.; Liebler, D.C.; Na, M.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Rodriguez-Ropero, F.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, tetrahydro-2-methyl-4-methylene-6-phenyl-2H-pyrane, CAS Registry number 30310-41-9
Food and Chemical Toxicology : FCT, Vol.134 (2019), Supplement 1, Art. 110593
info:doi/10.1016/j.fct.2019.110593
Fraunhofer ITEM


Api, A.M.; Belmonte, F.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Gadhia, S.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Lavelle, M.; Liebler, D.C.; Na, M.; O'Brien, D.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, theaspirane, CAS Registry Number 36431-72-8
Food and Chemical Toxicology : FCT, Vol.134 (2019), Supplement 1, Art. 110620
info:doi/10.1016/j.fct.2019.110620
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. La; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM Fragrance Ingredient Safety Assessment,(E,Z)-2,6-nonadien-1-ol acetate, CAS Registry Number 68555-65-7
Food and Chemical Toxicology : FCT, Vol.127 (2019), Supplement 1, pp.S216-S223
info:doi/10.1016/j.fct.2019.03.023
Fraunhofer ITEM


Danov, Olga; Laßwitz, Lisa; Obernolte, Helena; Hesse, Christina; Braun, Armin; Wronski, Sabine; Sewald, Katherina:
Rupintrivir reduces RV-induced TH-2 cytokine IL-4 in precision-cut lung slices (PCLS) of HDM-sensitized mice ex vivo
Respiratory research. Online journal, Vol.20 (2019), Art. 228, 9 pp.
info:doi/10.1186/s12931-019-1175-y
Fraunhofer ITEM


Renner, Andreas; Romanova, Julia; Ferko, Boris; Schmutz, Helmut; Nebolsin, Vladimir; Müller, Meike; Badorrek, Philipp; Marth, Katharina; Pohl, Wolfgang:
Safety, pharmacokinetics and pharmacodynamics of a novel anti-asthmatic drug, XC8, in healthy probands
Pulmonary pharmacology & therapeutics, Vol.59 (2019), Art. 101852, 6 pp.
info:doi/10.1016/j.pupt.2019.101852
Fraunhofer ITEM


Alberter, Barbara; Scheitler, Sebastian; Feliciello, Giancarlo; Ferrarini, Alberto; Werner-Klein, Melanie; Haferkamp, Sebastian; Klein, Christoph A.; Polzer, Bernhard:
Semi-automated detection, isolation and molecular analysis of single disseminated melanoma cells from lymph nodes. (American Association for Cancer Research (AACR Annual Meeting) <2019, Atlanta/Ga.>)
Cancer research, Vol.79 (2019), No.13, Supplement, Abstract 431
info:doi/10.1158/1538-7445.AM2019-431
Fraunhofer ITEM


Carstensen, Saskia; Holz, Olaf; Müller, Meike; Hohlfeld, Jens M.:
Sputum Analysis by Chipcytometry Following LPS Inhalation Challenge. (American Thoracic Society (ATS International Conference) <2019, Dallas/Tex.>)
American Journal of Respiratory and Critical Care Medicine, Vol.199 (2019), Abstract A5742
info:doi/10.1164/ajrccm-conference.2019.199.1_MeetingAbstracts.A4535
Fraunhofer ITEM


Tariq, K.; Schofield, James P.R.; Nicholas, Ben; Burg, Dominic; Brandsma, Joost; Bansal, Aruna T.; Wilson, Susan J.; Lutter, René; Fowler, Stephen J.; Bakke, Per; Caruso, Massimo; Dahlén, Barbro; Horvath, Ildiko; Krug, Norbert; Montuschi, Paolo; Sanak, Marek; Sandstrom, Thomas; Geiser, Thomas; Pandis, Ioannis; Sousa, Ana R.; Adcock, Ian M.; Shaw, Dominick E.; Auffray, Charles; Howarth, Peter H.; Sterk, Peter J.; Chung, Kian Fan; Skipp, Paul J.; Dimitrov, Borislav; Djukanovic, Ratko:
Sputum proteomic signature of gastro-oesophageal reflux in patients with severe asthma
Respiratory Medicine, Vol.150 (2019), pp.66-73
info:doi/10.1016/j.rmed.2019.02.008
Fraunhofer ITEM


Terhechte, Arno; Appel, Bernhard; Clevermann, Konstantin; Färber, Christa; Heina, Martina; Kwiatkowski, Eberhard; Klappauf, Eberhard; Layher, Christof:
Statische Daten vs. dynamische Daten
Bertini, R.: Datenintegrität in der pharmazeutischen Industrie: Anwendung - Praxisbeispiele - Audit Trail. Aulendorf: ECV Editio Cantor Verlag, 2019, pp. 182-191
Fraunhofer ITEM


Schofield, J.P.R.; Burg, D.; Nicholas, B.; Strazzeri, F.; Brandsma, J.; Staykova, D.; Folisi, C.; Bansal, A.T.; Xian, Y.; Guo, Y.; Rowe, A.; Corfield, J.; Wilson, S.; Ward, J.; Lutter, R.; Shaw, D.E.; Bakke, P.S.; Caruso, M.; Dahlen, S.-E.; Fowler, S.J.; Horvath, I.; Howarth, P.; Krug, N.; Montuschi, P.; Sanak, M.; Sandström, T.; Sun, K.; Pandis, I.; Riley, J.; Auffray, C.; Meulder, B. De; Lefaudeux, D.; Sousa, A.R.; Adcock, I.M.; Chung, K.F.; Sterk, P.J.; Skipp, P.J.; Djukanović, R.:
Stratification of asthma phenotypes by airway proteomic signatures
The journal of allergy and clinical immunology : JACI, Vol.144 (2019), No.1, pp.70-82
info:doi/10.1016/j.jaci.2019.03.013
Fraunhofer ITEM


Requardt, H.; Braun, A.; Steinberg, P.; Hampel, S.; Hansen, T.:
Surface defects reduce Carbon Nanotube toxicity in vitro
Toxicology in vitro, Vol.60 (2019), pp.12-18
info:doi/10.1016/j.tiv.2019.03.028
Fraunhofer ITEM


Klatt, Denise; Cheng, Erica; Philipp, Friederike; Selich, Anton; Dahlke, Julia; Schmidt, Reinhold E.; Schott, Juliane W.; Büning, Hildegard; Hoffmann, Dirk; Thrasher, Adrian J.; Schambach, Axel:
Targeted Repair of p47-CGD in iPSCs by CRISPR/Cas9: Functional Correction without Cleavage in the Highly Homologous Pseudogenes
Stem cell reports, Vol.13 (2019), No.4, pp.590-598
urn:nbn:de:0011-n-5648533
info:doi/10.1016/j.stemcr.2019.08.008
Volltext
Fraunhofer ITEM


Klatt, Denise; Cheng, Erica; Philipp, Friederike; Selich, Anton; Dahlke, Julia; Schmidt, Reinhold E.; Schott, Juliane W.; Hoffmann, Dirk; Thrasher, Adrian J.; Schambach, Axel:
Targeted Repair of p47-CGD Restores the Ability of iPSC-Derived Macrophages to Kill Bacteria. (American Society of Gene & Cell Therapy (ASGCT Annual Meeting) <22, 2019, Washington/DC>)
Molecular therapy, Vol.27 (2019), No.4, Supplement 1, Abstract 713
Fraunhofer ITEM


Durst, F.C.; Grujovic, A.; Ganser, I.; Hoffmann, M.; Ugocsai, P.; Klein, C.A.; Czyz, Z.T.:
Targeted transcript quantification in single disseminated cancer cells after whole transcriptome amplification
PLoS one. Online journal, Vol.14 (2019), No.8, Art.e0216442, 21 pp.
info:doi/10.1371/journal.pone.0216442
Fraunhofer ITEM


Werner-Klein, M.; Klein, C.A.:
Therapy resistance beyond cellular dormancy
Nature cell biology, Vol.21 (2019), No.2, pp.117-119
info:doi/10.1038/s41556-019-0276-7
Fraunhofer ITEM


Escher, Sylvia E.; Kamp, Hennicke; Bennekou, Susanne Hougaard; Bitsch, Annette; Fisher, Ciarán; Gräpel, Rabea; Hengstler, Jan G.; Herzler, Matthias; Knight, Derek; Leist, Marcel; Norinder, Ulf; Ouédraogo, Gladys; Pastor, Manuel; Stuard, Sharon; White, Andrew; Zdrazil, Barbara; Water, Bob van de; Kroese, Dinant:
Towards grouping concepts based on new approach methodologies in chemical hazard assessment: The read-across approach of the EU-ToxRisk project: Guest Editorial
Archives of toxicology, Vol.93 (2019), No.12, pp.3643-3667
info:doi/10.1007/s00204-019-02591-7
Fraunhofer ITEM


Reamon-Buettner, S.M.; Niehof, M.; Hirth, N.; Danov, O.; Obernolte, H.; Braun, A.; Warnecke, J.; Sewald, K.; Wronski, S.:
Transcriptomic Analysis Reveals Priming of The Host Antiviral Interferon Signaling Pathway by Bronchobini® Resulting in Balanced Immune Response to Rhinovirus Infection in Mouse Lung Tissue Slices
International journal of molecular sciences, Vol.20 (2019), No.9, Art.2242
info:doi/10.3390/ijms20092242
Fraunhofer ITEM


Ziemann, Christina; Reamon-Buettner, Stella Marie; Lison, D.; Brûle, Sybille van den; Bonner, J.C.; Creutzenberg, Otto H.:
Transcriptomic signatures in human LP9 mesothelial cells after treatment with differentially purified and surface functionalized multiwalled carbon nanotubes. (Society of Toxicology (Annual Meeting) <58, 2019, Baltimore/Md.>)
The Toxicologist, Vol.168 (2019), No.1, Abstract PL 3290
Fraunhofer ITEM


Simpson, A.J.; Hekking, P.-P.; Shaw, D.E.; Fleming, L.J.; Roberts, G.; Riley, J.H.; Bates, S.; Sousa, A.R.; Bansal, A.T.; Pandis, I.; Sun, K.; Bakke, P.S.; Caruso, M.; Dahlen, B.; Dahlen, S.-E.; Horvath, I.; Krug, N.; Montuschi, P.; Sandstrom, T.; Singer, F.; Adcock, I.M.; Wagers, S.S.; Djukanovic, R.; Chung, K.F.; Sterk, P.J.; Fowler, S.J.; Hohlfeld, J.M.; et al.:
Treatable traits in the European U-BIOPRED adult asthma cohorts
Allergy. European journal of allergy and clinical immunology, Vol.74 (2019), No.2, pp.406-411
info:doi/10.1111/all.13629
Fraunhofer ITEM


Heusser, K.; Tank, J.; Holz, O.; May, M.; Brinkmann, J.; Engeli, S.; Diedrich, A.; Framke, T.; Koch, A.; Großhennig, A.; Danser, A.H.J.; Sweep, F.C.G.J.; Schindler, C.; Schwarz, K.; Krug, N.; Jordan, J.; Hohlfeld, J.M.:
Ultrafine particles and ozone perturb norepinephrine clearance rather than centrally generated sympathetic activity in humans
Scientific Reports, Vol.9 (2019), Art. 3641, 10 pp.
info:doi/10.1038/s41598-019-40343-w
Fraunhofer ITEM


Solecki, R.; Rauch, M.; Gall, A.; Buschmann, J.; Kellner, R.; Kucheryavenko, O.; Schmitt, A.; Delrue, N.; Li, W.; Hu, J.; Fujiwara, M.; Kuwagata, M.; Mantovani, A.; Makris, S.L.; Paumgartten, F.; Schönfelder, G.; Schneider, S.; Vogl, S.; Kleinstreuer, N.; Schneider, M.; Schulze, F.; Fritsche, E.; Clark, R.; Shiota, K.; Chahoud, I.:
Update of the DevTox data database for harmonized risk assessment and alternative methodologies in developmental toxicology: Report of the 9th Berlin Workshop on Developmental Toxicity
Reproductive toxicology, Vol.89 (2019), pp.124-129
info:doi/10.1016/j.reprotox.2019.07.003
Fraunhofer ITEM


Ehrlich, Tomke; Scharfenberg, Klaus (Erstprüfer); Ziemann, Christina (Zweitprüferin) :
Vergleichende Untersuchungen zum toxischen und gentoxischen Potenzial von verschiedenen, oberflächenmodifizierten Kohlenstoffnanoröhren in humanen Lungenfibroblasten
Emden-Leer, Hochschule, Bachelor Thesis, 2019
Fraunhofer ITEM


Brinke, A. ten; Martinze-Llordella, M.; Cools, N.; Hilkens, C.M.U.; Ham, S.M. van; Sawitzki, B.; Geissler, E.K.; Lombardi, G.; Trzonkowski, P.; Martinez-Caceres, E.:
Ways forward for tolerance-inducing cellular therapies - an AFACTT perspective
Frontiers in Immunology, Vol.10 (2019), Art. 181, 20 pp.
urn:nbn:de:0011-n-5828113
info:doi/10.3389/fimmu.2019.00181
Volltext
Fraunhofer ITEM


Zobl, W.; Afrapoli, F.M.; Escher, S.E.:
What can an animal tell the toxicologist? Concordance of toxic effects to liver and kidney between rats and humans. (European Societies of Toxicology (EUROTOX Congress) <55, 2019, Helsinki>)
Toxicology letters, Vol.314 (2019), Supplement, pp.S194-S195
Fraunhofer ITEM