Holz, Olaf; Kern, Agilo Luitger; Biller, Heike; Olin, Anna-Carin; Vogel-Claussen, Jens; Hohlfeld, Jens M.:
129Xenon-enhanced magnetic resonance imaging to understand particle exhalation from the human lung. (European Respiratory Society (ERS International Congress) <2018, Paris>)
European Respiratory Journal, Vol.52 (2018), Supplement 62, Abstract PA5056
info:doi/10.1183/13993003.congress-2018.PA5056
Fraunhofer ITEM


Schwarz, Katharina; Hansen, Tanja; Ritter, Detlef; Walter, Dorothee; Knebel, Jan:
Acute inhalation toxicity in vitro and ex vivo test battery prior to regulatory OECD 403 studies. (Society of Toxicology (Annual Meeting) <57, 2018, San Antonio/Tex.>)
The Toxicologist, Vol.162 (2018), No.1, pp.331, Abstract PS 2363
Fraunhofer ITEM


Lacroix, Ghislaine; Koch, Wolfgang; Ritter, Detlef; Gutleb, Arno C.; Larsen, Søren Thor; Loret, Thomas; Zanetti, Filippo; Constant, Samuel; Chortarea, Savvina; Rothen-Rutishauser, Barbara M.; Hiemstra, Pieter S.; Frejafon, Emeric; Hubert, Philippe; Gribaldo, Laura; Kearns, Peter; Aublant, Jean-Marc; Diabaté, Silvia; Weiss, Carsten; Groot, Antoinette de; Kooter, Ingeborg:
Air-liquid interface in vitro models for respiratory toxicology research: Consensus workshop and recommendations
Applied in vitro toxicology, Vol.4 (2018), No.2, pp.91-106
urn:nbn:de:0011-n-5249958
info:doi/10.1089/aivt.2017.0034
Volltext
Fraunhofer ITEM


Holz, Olaf; Heusser, Karsten; Müller, Meike; Windt, Horst; Schwarz, Katharina; Schindler, Christoph; Tank, Jens; Hohlfeld, Jens M.; Jordan, Jens:
Airway and systemic inflammatory responses to ultrafine carbon black particles and ozone in older healthy subjects
Journal of toxicology and environmental health. Pt.A, Vol.81 (2018), No.13, pp.576-588
info:doi/10.1080/15287394.2018.1463331
Fraunhofer ITEM


Siebers, Kathrin; Fink, Bijan; Zakrzewicz, Anna; Agné, Alisa; Richter, Katrin; Konzok, Sebastian; Hecker, Andreas; Zukunft, Sven; Küllmar, Mira; Klein, Jochen; McIntosh, J. Michael; Timm, Thomas; Sewald, Katherina; Padberg, Winfried; Aggarwal, Nupur; Chamulitrat, Walee; Santoso, Sentot; Xia, Wendy; Janciauskiene, Sabina; Grau, Veronika:
Alpha-1 antitrypsin inhibits ATP-mediated release of interleukin-1β via CD36 and nicotinic acetylcholine receptors
Frontiers in Immunology, Vol.9 (2018), Art. 877, 15 pp.
urn:nbn:de:0011-n-5099248
info:doi/10.3389/fimmu.2018.00877
Volltext
Fraunhofer ITEM


Ziemann, Sebastian; Linde, Karina van der; Lahrmann, Urs; Acar, Beyda; Kaschani, Farnusch; Colby, Tom; Kaiser, Markus; Ding, Yezhang; Schmelz, Eric; Huffaker, Alisa; Holton, Nicholas; Zipfel, Cyril; Doehlemann, Gunther:
An apoplastic peptide activates salicylic acid signalling in maize
Nature plants, Vol.4 (2018), No.3, pp.172-180
info:doi/10.1038/s41477-018-0116-y
Fraunhofer ITEM


Toropova, Alla P.; Toropov, Andrey A.; Marzo, Marco; Escher, Sylvia E.; Dorne, Jean Lou; Georgiadis, Nikolaos; Benfenati, Emilio:
The application of new HARD-descriptor available from the CORAL software to building up NOAEL models
Food and Chemical Toxicology : FCT, Vol.112 (2018), pp.544-550
info:doi/10.1016/j.fct.2017.03.060
Fraunhofer ITEM


Schwotzer, Daniela; Meyer-Plath, Asmus; Rittinghausen, Susanne; Creutzenberg, Otto H.; Leonhardt, Albrecht; Schaudien, Dirk:
Approaches on MWCNT diameters and its relation to tumor development. (German Society for Experimental and Clinical Pharmacology and Toxicology (DGPT Annual Meeting) <84, 2018, Göttingen>)
Naunyn-Schmiedebergs archives of pharmacology, Vol.391 (2018), Supplement 1, pp.S52
info:doi/10.1007/s00210-018-1477-5
Fraunhofer ITEM


Neuhaus, Vanessa; Danov, Olga; Konzok, Sebastian; Obernolte, Helena; Dehmel, Susann; Braubach, Peter; Jonigk, Danny; Fieguth, Hans-Gerd; Zardo, Patrick; Warnecke, Gregor; Martin, Christian; Braun, Armin; Sewald, Katherina:
Assessment of the cytotoxic and immunomodulatory effects of substances in human precision-cut lung slices
Journal of visualized experiments : JoVE. Online resource, Vol.135 (2018), Art. e57042, 14 pp.
urn:nbn:de:0011-n-5100690
info:doi/10.3791/57042
Volltext
Fraunhofer ITEM


Pohlmann, Gerhard; Hohlfeld, Jens M.; Haidl, Peter; Pankalla, Jelena; Cloes, Rolf-Michael:
Assessment of the power required for optimal use of current inhalation devices
Journal of aerosol medicine and pulmonary drug delivery, Vol.31 (2018), No.6, pp.339-346
info:doi/10.1089/jamp.2017.1376
Fraunhofer ITEM


Iwaschenko, Peter; Pohlmann, Gerhard; Wiegandt, Felix:
Atemgesteuerte Applikation von pulverförmigen Aerosol bei der Beatmung oder Atemunterstützung eines Patienten
2018
Fraunhofer ITEM


Happle, Christine; Jirmo, Adan Chari; Meyer-Bahlburg, Almut; Habener, Anika; Hoymann, Heinz-Gerd; Hennig, Christian; Skuljec, Jelena; Hansen, Gesine:
B cells control maternofetal priming of allergy and tolerance in a murine model of allergic airway inflammation
The journal of allergy and clinical immunology : JACI, Vol.141 (2018), No.2, pp.685-696
info:doi/10.1016/j.jaci.2017.03.051
Fraunhofer ITEM


Lapp, Stefanie; Bube, Axel; Colbatzky, Florian A.; Ernst, Heinrich; Kellner, Rupert; Nolte, Thomas; Rinke, Matthias:
Best practice approach for assessment of microchip-associated tumors in preclinical safety studies: Position of the Registry of Industrial Toxicology Animal-data (RITA)
Toxicologic Pathology, Vol.46 (2018), No.7, pp.728-734
info:doi/10.1177/0192623318792541
Fraunhofer ITEM


Ackermann, Mania; Kempf, Henning; Hetzel, Miriam; Hesse, Christina; Hashtchin, Anna Rafiei; Brinkert, Kerstin; Schott, Juliane Wilhelmine; Haake, Kathrin; Kühnel, Mark Philipp; Glage, Silke; Figueiredo, Constanca; Jonigk, Danny; Sewald, Katherina; Schambach, Axel; Wronski, Sabine; Moritz, Thomas; Martin, Ulrich; Zweigerdt, Robert; Munder, Antje; Lachmann, Nico:
Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections
Nature Communications, Vol.9 (2018), Art. 5088, 13 pp.
urn:nbn:de:0011-n-5376833
info:doi/10.1038/s41467-018-07570-7
Volltext
Fraunhofer ITEM


Küppers, L.; Holz, Olaf; Schuchardt, Sven; Gottlieb, J.; Fuge, J.; Greer, M.; Hohlfeld, Jens M.:
Breath volatile organic compounds of lung transplant recipients with and without chronic lung allograft dysfunction
Journal of breath research, Vol.12 (2018), No.3, Art. 036023, 14 pp.
urn:nbn:de:0011-n-4977217
info:doi/10.1088/1752-7163/aac5af
Volltext
Fraunhofer ITEM


Behrens, Ailke; Foremny, Katharina; Doll, Theodor:
Carbon nanotube-silicone rubber on active thin-film implants
Physica status solidi. A, Vol.215 (2018), No.15, Art. 1700873, 5 pp.
info:doi/10.1002/pssa.201700873
Fraunhofer ITEM


Schwotzer, Daniela; Niehof, Monika; Schaudien, Dirk; Kock, Heiko; Hansen, Tanja; Dasenbrock, Clemens; Creutzenberg, Otto H.:
Cerium oxide and barium sulfate nanoparticle inhalation affects gene expression in alveolar epithelial cells type II
Journal of nanobiotechnology. Online journal, Vol.16 (2018), Art. 16, 25 pp.
urn:nbn:de:0011-n-4975408
info:doi/10.1186/s12951-018-0343-4
Volltext
Fraunhofer ITEM


Laux, Peter; Riebeling, Christian; Booth, Andy M.; Brain, Joseph D.; Brunner, Josephine; Cerrillo, Cristina; Creutzenberg, Otto H.; Estrela-Lopis, Irina; Gebel, Thomas; Johanson, Gunnar; Jungnickel, Harald; Kock, Heiko; Tentschert, Jutta; Tlili, Ahmed; Schäffer, Andreas; Sips, Adriënne J.A.M.; Yokel, Robert A.; Luch, Andreas:
Challenges in characterizing the environmental fate and effects of carbon nanotubes and inorganic nanomaterials in aquatic systems
Environmental science. Nano, Vol.5 (2018), No.1, pp.48-63
urn:nbn:de:0011-n-5099266
info:doi/10.1039/c7en00594f
Volltext
Fraunhofer ITEM


Elenschneider, Leroy; Knebel, Jan; Braun, Armin; Fangmann, J.; Hansen, Tanja:
Characterization of human precision cut liver slices by various viability andfunctional parameters during 24 hour culture. (Society of Toxicology (Annual Meeting) <57, 2018, San Antonio/Tex.>)
The Toxicologist, Vol.162 (2018), No.1, pp.520, Abstract PS 3152
Fraunhofer ITEM


Leeming, Diana Julie; Sand, Jannie M.B.; Hesse, Christina; Konzok, Sebastian; Sewald, Katherina; Rønnow, Sarah; Braun, Armin; Karsdal, Morten A.; Brockbank, Sarah; Cruwys, Simon:
Clinically validated markers of the extracellular matrix remodelling are altered by potential anti-fibrotic compounds in a human lung fibrosis ex vivo model. (European Respiratory Society (ERS International Congress) <2018, Paris>)
European Respiratory Journal, Vol.52 (2018), Supplement 62, Abstract PA5255
info:doi/10.1183/13993003.congress-2018.PA5255
Fraunhofer ITEM


Walter, Dorothee; Ritter, Detlef; Knebel, Jan; Schwarz, Katharina; Hansen, Tanja:
A combination of in-vitro and ex-vivo test models as an upstream alternative to regulatory OECD 403 animal studies. (German Society for Experimental and Clinical Pharmacology and Toxicology (DGPT Annual Meeting) <84, 2018, Göttingen>)
Naunyn-Schmiedebergs archives of pharmacology, Vol.391 (2018), Supplement 1, pp.S79
info:doi/10.1007/s00210-018-1477-5
Fraunhofer ITEM


Juling, Sabine; Böhmert, Linda; Lichtenstein, Dajana; Oberemm, Axel; Creutzenberg, Otto H.; Thünemann, Andreas F.; Braeuning, Albert; Lampen, Alfonso:
Comparative proteomic analysis of hepatic effects induced by nanosilver, silver ions and nanoparticle coating in rats
Food and Chemical Toxicology : FCT, Vol.113 (2018), pp.255-266
info:doi/10.1016/j.fct.2018.01.056
Fraunhofer ITEM


Kaireit, Till F.; Gutberlet, Marcel; Voskrebenzev, Andreas; Freise, Julia; Welte, Tobias; Hohlfeld, Jens M.; Wacker, Frank; Vogel-Claussen, Jens:
Comparison of quantitative regional ventilation‐weighted fourier decomposition MRI with dynamic fluorinated gas washout MRI and lung function testing in COPD patients
Journal of magnetic resonance imaging, Vol.47 (2018), 6, pp.1534-1541
info:doi/10.1002/jmri.25902
Fraunhofer ITEM


Pedersen, Frauke; Zissler, U.; Watz, Henrik; Rabe, Klaus F.; Hohlfeld, Jens M.; Holz, Olaf:
A comprehensive way to rate sputum quality in clinical trials. (American Thoracic Society (ATS International Conference) <2018, San Diego/Calif.>)
American Journal of Respiratory and Critical Care Medicine, Vol.197 (2018), Art. A4769
Fraunhofer ITEM


Meulder, Bertrand de; Lefaudeux, Diane; Bansal, Aruna T.; Mazein, Alexander; Chaiboonchoe, Amphun; Ahmed, Hassan; Balaur, Irina; Saqi, Mansoor; Pellet, Johann; Ballereau, Stephane; Lemonnier, Nathanaël; Sun, Kai; Pandis, Ioannis; Yang, Xian; Batuwitage, Manohara; Kretsos, Kosmas; Eyll, Jonathan van; Bedding, Alun; Davison, Timothy; Dodson, Paul; Larminie, Christopher; Postle, Anthony; Corfield, Julie; Djukanović, Ratko; Chung, Kian Fan; Adcock, Ian M.; Guo, Yi-Ke; Sterk, Peter J.; Manta, Alexander; Rowe, Anthony; Baribaud, Frédéric; Auffray, Charles; Badorrek, Philipp; Faulenbach, Cornelia; Braun, Armin; Hohlfeld, Jens; Krug, Norbert:
A computational framework for complex disease stratification from multiple large-scale datasets
BMC systems biology. Online journal, Vol.12 (2018), Art. 60, 23 pp.
urn:nbn:de:0011-n-5249900
info:doi/10.1186/s12918-018-0556-z
Volltext
Fraunhofer ITEM


Knebel, Jan W.; Ritter, Detlef; Niehof, Monika; Hansen, Tanja; Strandh, M.; Falciani, C.; Flores, M.; Welscher, Y. te; Nostrum, C. van; Gracia, R.; Marradi, M.; Loinaz, I.:
Cytotoxicity testing of therapeutic nanosystems for pulmonary infection using an air-lifted interphase in-vitro test system. (European Societies of Toxicology (EUROTOX Congress) <54, 2018, Brussels>)
Toxicology letters, Vol.295 (2018), Supplement 1, pp.S69
info:doi/10.1016/j.toxlet.2018.06.520
Fraunhofer ITEM


Ritter, Detlef; Bitsch, Annette; Elend, Manfred; Schuchardt, Sven; Hansen, Tanja; Brodbeck, Carsten; Knebel, Jan; Fuchs, Anne; Gronewold, Claas; Fautz, Rolf:
Development and evaluation of an in vitro test system for toxicity screening of aerosols released from consumer products and first application to aerosols from a hair straightening process
Applied in vitro toxicology, Vol.4 (2018), No.2, pp.180-192
info:doi/10.1089/aivt.2017.0036
Fraunhofer ITEM


Oltmanns, J.; Licht, O.; Bitsch, Annette; Bohlen, M.-L.; Escher, Sylvia E.; Silano, V.; MacLeod, M.; Serafimova, R.; Kass, G.E.N.; Merten, C.:
Development of a novel scoring system for identifying emerging chemical risks in the food chain
Environmental science, Vol.20 (2018), No.2, pp.340-353
info:doi/10.1039/c7em00564d
Fraunhofer ITEM


Cronin, M.T.D.; Belfield, S.; Escher, Sylvia E.; Firman, J.; Liu, J.; Marsaux, C.; Mostrag-Szlichtyng, A.; Przybylak, K.; Rathman, J.; Tarkhov, Aleksey; Yang, C.:
Development of an updated carcinogenicity potency database and analysis of thresholds of toxicological concern. (Society of Toxicology (Annual Meeting) <57, 2018, San Antonio/Tex.>)
The Toxicologist, Vol.162 (2018), No.1, pp.286, Abstract PS 2102
Fraunhofer ITEM


Doll, Theodor; Pohlmann, Gerhard; Sieghorst, Jan:
Dezellularisierte Implantathüllen
2018
Fraunhofer ITEM


Hoffmann, Martin; Pasch, Sophie; Schamberger, Thomas; Maneck, Matthias; Möhlendick, Birte; Schumacher, Sarah; Brockhoff, Gero; Knoefel, Wolfram Trudo; Izbicki, Jakob; Polzer, Bernhard; Stoecklein, Nikolas H.; Klein, Christoph A.:
Diagnostic pathology of early systemic cancer: ERBB2 gene amplification in single disseminated cancer cells determines patient survival in operable esophageal cancer
International journal of cancer, Vol.142 (2018), No.4, pp.833-843
info:doi/10.1002/ijc.31108
Fraunhofer ITEM


Aeffner, Famke; Adissu, Hibret A.; Boyle, Michael C.; Cardiff, Robert D.; Hagendorn, Erik; Hoenerhoff, Mark J.; Klopfleisch, Robert; Newbigging, Susan; Schaudien, Dirk; Turner, Oliver; Wilson, Kristin:
Digital microscopy, image analysis, and virtual slide repository
ILAR journal, Vol.59 (2018), No.1, pp.66-79
info:doi/10.1093/ilar/ily007
Fraunhofer ITEM


Obernolte, Helena; Ritter, Detlef; Knebel, Jan; Braubach, Peter; Jonigk, Danny; Warnecke, Gregor; Zardo, Patrick; Fieguth, Hans-Gerd; Pfennig, Olaf; Braun, Armin; Sewald, Katherina:
Early biomarkers indicating COPD can be induced by whole cigarette smoke in fresh human lung tissue
Pneumologie, Vol.72 (2018), No.3, pp.224
info:doi/10.1055/s-0037-1615306
Fraunhofer ITEM


Hohlfeld, Jens M.; Vogel-Claussen, Jens; Biller, Heike; Berliner, Dominik; Berschneider, Korbinian; Tillmann, Hanns-Christian; Hiltl, Simone; Bauersachs, Johann; Welte, Tobias:
Effect of lung deflation with indacaterol plus glycopyrronium on ventricular filling in patients with hyperinflation and COPD (CLAIM): A double-blind, randomised, crossover, placebo-controlled, single-centre trial
The lancet. Respiratory medicine, Vol.6 (2018), No.5, pp.368-378
info:doi/10.1016/S2213-2600(18)30054-7
Fraunhofer ITEM


Wronski, Sabine; Dannenmaier, Julia; Schild, Sabine; Macke, Olaf; Müller, Laura; Burmeister, Yvonne; Seilheimer, Bernd; Müller, Meike:
Engystol reduces onset of experimental respiratory syncytial virus-induced respiratory inflammation in mice by modulating macrophage phagocytic capacity
PLoS one. Online journal, Vol.13 (2018), No.4, Art. e0195822, 13 pp.
urn:nbn:de:0011-n-4976183
info:doi/10.1371/journal.pone.0195822
Volltext
Fraunhofer ITEM


Emma, Rosalia; Bansal, Aruna T.; Kolmert, Johan; Wheelock, Craig E.; Dahlén, Sven-Erik; Loza, Matthew J.; Meulder, Bertrand de; Lefaudeux, Diane; Auffray, Charles; Dahlén, Barbro; Bakke, Per S.; Chanez, Pascal; Fowler, Stephen J.; Horvath, Ildiko; Montuschi, Paolo; Krug, Norbert; Sanak, Marek; Sandström, Thomas; Shaw, Dominick E.; Fleming, Louise J.; Djukanovic, Ratko; Howarth, Peter H.; Singer, Florian; Sousa, Ana R.; Sterk, Peter J.; Corfield, Julie; Pandis, Ioannis; Chung, Kian F.; Adcock, Ian M.; Lutter, René; Fabbella, Lorena; Caruso, Massimo:
Enhanced oxidative stress in smoking and ex-smoking severe asthma in the U-BIOPRED cohort
PLoS one. Online journal, Vol.13 (2018), No.9, Art. e0203874, 16 pp.
urn:nbn:de:0011-n-5243717
info:doi/10.1371/journal.pone.0203874
Volltext
Fraunhofer ITEM


Abt, Felix; Kopp, Harald (Betreuer); Diemar, Ute (Betreuer) :
Entwicklung einer Logistikkonzeption für eine dezentrale Fertigung von medizinischen Prüfprodukten
Furtwangen, Hochschule, Master Thesis, 2018
Fraunhofer ITEM


Escher, Sylvia E.:
EUToxRisk case studies: new approach methodologies in read-across. (Society of Toxicology (Annual Meeting) <57, 2018, San Antonio/Tex.>)
The Toxicologist, Vol.162 (2018), No.1, pp.394-395, Abstract W 2632
Fraunhofer ITEM


Tóth, B.; Bernstein, David M.; Rogers, R.A.; Kunzendorf, Peter; Ernst, Heinrich:
Evaluation of the dose-response and fate in the lung and pleura of chrysotile containing brake dust compared to chrysotile or crocidolite asbestos in a 28 day inhalation toxicology study. (European Societies of Toxicology (EUROTOX Congress) <54, 2018, Brussels>)
Toxicology letters, Vol.295 (2018), Supplement 1, pp.S174
info:doi/10.1016/j.toxlet.2018.06.814
Fraunhofer ITEM


Bernstein, D.M.; Tóth, B.; Rogers, R.A.; Kunzendorf, P.; Ernst, Heinrich:
Evaluation of the dose-response and fate in the lung and pleura of chrysotile containing brake dust compared to chrysotile or crocidolite asbestos in a 28-day inhalation toxicology study. (Society of Toxicology (Annual Meeting) <57, 2018, San Antonio/Tex.>)
The Toxicologist, Vol.162 (2018), No.1, pp.45
Fraunhofer ITEM


Bernstein, D.M.; Tóth, B.; Rogers, R.A.; Sepulveda, R.; Kunzendorf, P.; Phillips, J.I.; Ernst, Heinrich:
Evaluation of the dose-response and fate in the lung and pleura of chrysotile-containing brake dust compared to chrysotile or crocidolite asbestos in a 28-day quantitative inhalation toxicology study
Toxicology and Applied Pharmacology, Vol.351 (2018), pp.74-92
urn:nbn:de:0011-n-4977233
info:doi/10.1016/j.taap.2018.04.033
Volltext
Fraunhofer ITEM


Weber, Elena; Illing, Gerhard (1. Gutachter); Weigt, Henning (2. Gutachter) :
Evaluierung der ökotoxikologischen Risikobewertung für genmodifizierte Arzneimittel
Emden-Leer, Hochschule, Master Thesis, 2018
Fraunhofer ITEM


Escher, Sylvia E.; Tluczkiewicz, Inga; Hansen, Tanja; Niehof, Monika; Knebel, Jan; Ritter, Detlef; Danov, Olga; Obernolte, Helena; Schramm, Sinja-Fee; Koschmann, Jeannette; Kel, Alexander; Wingender, Edgar; Meckbach, Cornelia; Boomgarden, Wolfgang; Sewald, Katherina:
EXITOX-II: Development of an animal free testing strategy for the risk assessment of inhalable compounds. (German Society for Experimental and Clinical Pharmacology and Toxicology (DGPT Annual Meeting) <84, 2018, Göttingen>)
Naunyn-Schmiedebergs archives of pharmacology, Vol.391 (2018), Supplement 1, pp.S9
info:doi/10.1007/s00210-018-1477-5
Fraunhofer ITEM


Marcoleta, Juan Pablo; Nogueira, Waldo; Froriep, Ulrich Paul; Doll, Theodor:
Flexible high density active neural implants combining a distributed multiplexing transceiver architecture with biocompatible technology
Physica status solidi. A, Vol.215 (2018), No.15, Art. 1700134, 10 pp.
info:doi/10.1002/pssa.201700134
Fraunhofer ITEM


Nastevska, Cathrin (Red.); Schlemminger, Karin (Übers.) ; Fraunhofer-Institut für Toxikologie und Experimentelle Medizin -ITEM-, Hannover:
Fraunhofer-Institut für Toxikologie und Experimentelle Medizin. Leistungen und Ergebnisse. Jahresbericht 2017
Hannover: Fraunhofer ITEM, 2018
urn:nbn:de:0011-n-5032330
Volltext
Fraunhofer ITEM


Nastevska, Cathrin (Red.); Schlemminger, Karin (Übers.) ; Fraunhofer-Institut für Toxikologie und Experimentelle Medizin -ITEM-, Hannover:
Fraunhofer-Institute for Toxicology and Experimental Medicine. Performance and Results. Annual Report 2017
Hannover: Fraunhofer ITEM, 2018
urn:nbn:de:0011-n-5032563
Volltext
Fraunhofer ITEM


Gutberlet, Marcel; Kaireit, Till F.; Voskrebenzev, Andreas; Lasch, Florian; Freise, Julia; Welte, Tobias; Wacker, Frank; Hohlfeld, Jens M.; Vogel-Claussen, Jens:
Free-breathing dynamic (19)F gas MR imaging for mapping of regional lung ventilation in patients with COPD
Radiology, Vol.286 (2018), No.3, pp.1040-1051
info:doi/10.1148/radiol.2017170591
Fraunhofer ITEM


Greulich, Timm; Hohlfeld, Jens M.; Neuser, Petra; Lueer, Katrin; Klemmer, Andreas; Schade-Brittinger, Carmen; Harnisch, Susanne; Garn, Holger; Renz, Harald; Homburg, Ursula; Renz, Jonas; Kirsten, Anne; Pedersen, Frauke; Müller, Meike; Vogelmeier, Claus F.; Watz, Henrik:
A GATA3-specific DNAzyme attenuates sputum eosinophilia in eosinophilic COPD patients: A feasibility randomized clinical trial
Respiratory research. Online journal, Vol.19 (2018), Art. 55, 10 pp.
urn:nbn:de:0011-n-4976698
info:doi/10.1186/s12931-018-0751-x
Volltext
Fraunhofer ITEM


Tamò, Luca; Simillion, Cedric; Hibaoui, Yousse; Feki, Anis; Gugger, Mathias; Prasse, Antje; Jäger, Benedikt; Goldmann, Torsten; Geiser, Thomas; Gazdhar, Amiq:
Gene network analysis of interstitial macrophages after treatment with induced pluripotent stem cells secretome (iPSC-cm) in the bleomycin injured rat lung
Stem cell reviews and reports, Vol.14 (2018), No.3, pp.412-424
urn:nbn:de:0011-n-5125085
info:doi/10.1007/s12015-017-9790-9
Volltext
Fraunhofer ITEM


Werner-Klein, Melanie; Scheitler, Sebastian; Hoffmann, Martin; Hodak, Isabelle; Dietz, Klaus; Lehnert, Petra; Naimer, Veronika; Polzer, Bernhard; Treitschke, Steffi; Werno, Christian; Markiewicz, Aleksandra; Weidele, Kathrin; Czyz, Zbigniew; Hohenleutner, Ulrich; Hafner, Christian; Haferkamp, Sebastian; Berneburg, Mark; Rümmele, Petra; Ulmer, Anja; Klein, Christoph A.:
Genetic alterations driving metastatic colony formation are acquired outside of the primary tumour in melanoma
Nature Communications, Vol.9 (2018), Art. 595, 17 pp.
urn:nbn:de:0011-n-4975624
info:doi/10.1038/s41467-017-02674-y
Volltext
Fraunhofer ITEM


Volk, Joachim; Ziemann, Christina; Leyhausen, Gabriele; Geurtsen, Werner:
Genotoxic and mutagenic potential of camphorquinone in L5178/TK(+/-) mouse lymphoma cells
Dental materials, Vol.34 (2018), No.3, pp.519-530
info:doi/10.1016/j.dental.2017.12.013
Fraunhofer ITEM


Behr, Jürgen; Günther, Andreas; Bonella, Francesco; Geißler, Klaus; Koschel, Dirk; Kreuter, Michael; Prasse, Antje; Schönfeld, Nicolas; Sitter, Helmut; Müller-Quernheim, Joachim; Costabel, Ulrich:
German guideline for idiopathic pulmonary fibrosis - update on pharmacological therapies 2017
Pneumologie, Vol.72 (2018), No.2, pp.155-168
info:doi/10.1055/s-0043-123035
Fraunhofer ITEM


Vrijenhoek, N.G.; Gräpel, Rabea; Wink, S.; Escher, Sylvia E.; Water, Bob van de:
High throughput adaptive stress response pathway activation to support read across of valproic acid analogue-induced liver steatosis. (European Societies of Toxicology (EUROTOX Congress) <54, 2018, Brussels>)
Toxicology letters, Vol.295 (2018), Supplement 1, S194, Abstract P16-25
info:doi/10.1016/j.toxlet.2018.06.871
Fraunhofer ITEM


Vrijenhoek, N.G.; Gräpel, Rabea; Escher, Sylvia E.; Water, Bob van de:
High-throughput microscopy of adaptive stress response pathway activation by steatosis-inducing valproic acid analogues. (Society of Toxicology (Annual Meeting) <57, 2018, San Antonio/Tex.>)
The Toxicologist, Vol.162 (2018), No.1, pp.522, Abstract PS 3159
Fraunhofer ITEM


Müller, Laura; Murgia, Xabier; Siebenburger, Lorenz; Börger, Carsten; Schwarzkopf, Konrad; Sewald, Katherina; Häussler, Susanne; Braun, Armin; Lehr, Claus-Michael; Hittinger, Marius; Wronski, Sabine:
Human airway mucus alters susceptibility of Pseudomonas aeruginosa biofilms to tobramycin, but not colistin
Journal of antimicrobial chemotherapy : JAC, Vol.73 (2018), No.10, pp.2762-2769
info:doi/10.1093/jac/dky241
Fraunhofer ITEM


Danov, Olga; Jiménez Delgado, Sharon Melissa; Obernolte, Helena; Seehase, Sophie; Dehmel, Susann; Braubach, Peter; Fieguth, Hans-Gerd; Matschiner, Gabriele; Fitzgerald, Mary; Jonigk, Danny; Knauf, Sascha; Pfennig, Olaf; Warnecke, Gregor; Wichmann, Judy; Braun, Armin; Sewald, Katherina:
Human lung tissue provides highly relevant data about efficacy of new anti-asthmatic drugs
PLoS one. Online journal, Vol.13 (2018), No.11, Art. e0207767, 19 pp.
urn:nbn:de:0011-n-5239598
info:doi/10.1371/journal.pone.0207767
Volltext
Fraunhofer ITEM


Philipp, Friederike; Selich, Anton; Rothe, Michael; Hoffmann, Dirk; Rittinghausen, Susanne; Morgan, Michael A.; Klatt, Denise; Glage, Silke; Lienenklaus, Stefan; Neuhaus, Vanessa; Sewald, Katherina; Braun, Armin; Schambach, Axel:
Human teratoma-derived hematopoiesis is a highly polyclonal process supported by human umbilical vein endothelial cells
Stem cell reports, Vol.11 (2018), No.5, pp.1051-1060
urn:nbn:de:0011-n-5239581
info:doi/10.1016/j.stemcr.2018.09.010
Volltext
Fraunhofer ITEM


Kern, Agilo Luitger; Biller, Heike; Klimes, Filip; Voskrebenzev, Andreas; Gutberlet, Marcel; Rotärmel, Alexander; Schönfeld, Christian; Renne, Julius; Holz, Olaf; Wacker, Frank; Vogel-Claussen, Jens; Hohlfeld, Jens M.:
Hyperpolarized 129Xe functional MR imaging to monitor the response of human lungs after segmental lipopolysaccharide challenge. (American Thoracic Society (ATS International Conference) <2018, San Diego/Calif.>)
American Journal of Respiratory and Critical Care Medicine, Vol.197 (2018), Abastract A4725
Fraunhofer ITEM


Ziemann, Christina; Reamon-Buettner, Stella Marie; Lison, Dominique; Bonner, J.C.; Brûle, Sybille van den; Simon, S.; Creutzenberg, Otto H.:
ICONS - Integrated testing strategy for mechanistically assessing the respiratory toxicity of functionalized MWCNTs - Comparative in vitro investigations. (European Societies of Toxicology (EUROTOX Congress) <54, 2018, Brussels>)
Toxicology letters, Vol.295 (2018), Supplement 1, pp.S213, Abstract P17-26
info:doi/10.1016/j.toxlet.2018.06.922
Fraunhofer ITEM


Brinkman, P.; Wagener, A.H.; Hekking, P.-P.; Bansal, A.T.; Zee, A.-H. Maitland-van der; Wang, Y.; Weda, H.; Knobel, H.H.; Vink, T.J.; Rattray, N.J.; D'Amico, A.; Pennazza, G.; Santonico, M.; Lefaudeux, D.; Meulder, B. de; Auffray, C.; Bakke, P.S.; Caruso, M.; Chanez, P.; Chung, K.F.; Corfield, J.; Dahlén, S.-E.; Djukanovic, R.; Geiser, T.; Horvath, I.; Krug, N.; Musial, J.; Sun, K.; Riley, J.H.; Shaw, D.E.; Sandström, T.; Sousa, A.R.; Montuschi, P.; Fowler, S.J.; Sterk, P.J.:
Identification and prospective stability of electronic nose (eNose) - derived inflammatory phenotypes in patients with severe asthma
The journal of allergy and clinical immunology : JACI, Vol.143 (2018), No.5, pp.1811-1820
info:doi/10.1016/j.jaci.2018.10.058
Fraunhofer ITEM


Beneke, Valerie; Küster, Fennja; Neehus, Anna-Lena; Hesse, Christina; Lopez-Rodriguez, Elena; Haake, Kathrin; Rafiei Hashtchin, Anna; Schott, Juliane Wilhelmine; Walter, Dorothee; Braun, Armin; Wolkers, Willem F.; Ackermann, Mania; Lachmann, Nico:
An immune cell spray (ICS) formulation allows for the delivery of functional monocyte/macrophages
Scientific Reports, Vol.8 (2018), Art. 16281, 11 pp.
urn:nbn:de:0011-n-5240443
info:doi/10.1038/s41598-018-34524-2
Volltext
Fraunhofer ITEM


Neehus, Anna-Lena; Lam, Jenny; Haake, Kathrin; Merkert, Sylvia; Schmidt, Nico; Mucci, Adele; Ackermann, Mania; Schubert, Madline; Happle, Christine; Kühnel, Mark Philipp; Blank, Patrick; Philipp, Friederike; Goethe, Ralph; Jonigk, Danny; Martin, Ulrich; Kalinke, Ulrich; Baumann, Ulrich; Schambach, Axel; Roesler, Joachim; Lachmann, Nico:
Impaired IFNγ-signaling and mycobacterial clearance in IFNγR1-deficient human iPSC-derived macrophages
Stem cell reports, Vol.10 (2018), No.1, pp.7-16
urn:nbn:de:0011-n-4972343
info:doi/10.1016/j.stemcr.2017.11.011
Volltext
Fraunhofer ITEM


Mang, Samuel; Braun, Armin; Pairet, Nicolas; Lamb, David J.:
Importance of the IL-1 axis in haemophilus influenzae-stimulated M1 macrophages driving transepithelial signaling
American journal of respiratory cell and molecular biology, Vol.58 (2018), No.3, pp.412-415
info:doi/10.1165/rcmb.2017-0283LE
Fraunhofer ITEM


Zind, Laura; Troyke, Reiner; Turban, Kathrin; Schaudien, Dirk; Baumgärtner, Wolfgang; Hansmann, Florian:
Ein importierter Fall von feliner Leishmaniose in Deutschland und eine Literaturübersicht zur felinen Leishmaniose
Berliner und Münchener tierärztliche Wochenschrift, Vol.131 (2018), No.11-12, pp.506-512
info:doi/10.2376/0005-9366-17061
Fraunhofer ITEM


Schmeinck, Sina; Bitsch, Annette; Genth, Harald:
In depth analysis of selected cosmetic ingredients from the SkinAB database. (German Society for Experimental and Clinical Pharmacology and Toxicology (DGPT Annual Meeting) <84, 2018, Göttingen>)
Naunyn-Schmiedebergs archives of pharmacology, Vol.391 (2018), Supplement 1, pp.S77
info:doi/10.1007/s00210-018-1477-5
Fraunhofer ITEM


Amberg, A.; Anger, L.; Stolte, M.; Hemmerich, J.; Matter, H.; Fisk, L.; Tluczkiewicz, Inga; Pinto-Gil, K.; López-Massaguer, O.; Pastor, M.:
In silico prediction of DILI: Extraction of histopathology data from preclinical toxicity studies of the eTOX database for new in silico models of hepatotoxicity. (Society of Toxicology (Annual Meeting) <57, 2018, San Antonio/Tex.>)
The Toxicologist, Vol.162 (2018), No.1, pp.271
Fraunhofer ITEM


Sullivan, K.; Baker, N.; Cochrane, S.; Enoch, Steven J.; Ezendam, Janine; Patlewicz, G.; Roggen, Erwin L.; Settivari, R.; Sewald, Katherina:
In silico prediction of DILI: extraction of histopathology data from preclinical toxicity studies of the eTOX database for new in silico models of hepatotoxicity. (Society of Toxicology (Annual Meeting) <57, 2018, San Antonio/Tex.>)
The Toxicologist, Vol.162 (2018), No.1, Late-Breaking Supplement, pp.14-15, Abstract 3340
Fraunhofer ITEM


Fisher, C.P.; Hatley, O.; Vugt, B. van; Bois, F.; Escher, Sylvia E.; Gardner, Iain:
In vitro to in vivo extrapolation of valproic acid hepatotoxicity: A biokinetic and physiologically based toxicokinetic informed approach. (European Societies of Toxicology (EUROTOX Congress) <54, 2018, Brussels>)
Toxicology letters, Vol.295 (2018), Supplement 1, pp.S246, Abstract P24-03
info:doi/10.1016/j.toxlet.2018.06.1015
Fraunhofer ITEM


Dunkhorst, Wilhelm; Lipowicz, Peter; Li, Weiling; Hux, Casey; Wang, Qiang; Koch, Wolfgang:
In-situ characterization of e-cigarette aerosols by 90°-light scattering of polarized light
Aerosol science and technology, Vol.52 (2018), No.7, pp.717-724
info:doi/10.1080/02786826.2018.1464646
Fraunhofer ITEM


Müller, Laura; Kraemer, Nadine; Braubach, Peter; Jonigk, Danny; Fieguth, Hans-Gerd; Pfennig, Olaf; Bersch, Claus; Braun, Armin; Sewald, Katherina; Wronski, Sabine:
Induction of innate immune response in fresh human lung tissue ex vivo following P. aeruginosa infection. (European Respiratory Society (ERS International Congress) <2018, Paris>)
European Respiratory Journal, Vol.52 (2018), Supplement 62, Abstract PA4615
info:doi/10.1183/13993003.congress-2018.PA4615
Fraunhofer ITEM


Danov, Olga; Laßwitz, Lisa; Obernolte, Helena; Hesse, Christina; Braun, Armin; Wronski, Sabine; Sewald, Katherina:
Inflammatory exacerbation and inadequate interferone response to RV1b infection in HDM-sensitized lung tissue. (European Respiratory Society (ERS International Congress) <2018, Paris>)
European Respiratory Journal, Vol.52 (2018), Supplement 62, Abstract PA2654
info:doi/10.1183/13993003.congress-2018.PA2654
Fraunhofer ITEM


Rosenberger, Wolfgang; Schuchardt, Sven; Baumstark-Khan, C.; Hahn, A.:
Innenraumluftqualität in Verkehrsflugzeugen
Wichmann, H.E.: Handbuch der Umweltmedizin. Loseblattausgabe: Toxikologie, Epidemiologie, Hygiene, Belastungen, Wirkungen, Diagnostik, Prophylaxe. Landsberg/Lech: ecomed Verlagsgesellschaft, 2018, Kapitel VIII/7.3, 32 pp. (62. Ergänzungslieferung)
Fraunhofer ITEM


Wise, Sarah K.; Lin, Sandra Y.; Toskala, Elina; Orlandi, Richard R.; Akdis, Cezmi A.; Alt, Jeremiah A.; Azar, Antoine; Baroody, Fuad M.; Bachert, Claus; Canonica, G. Walter; Chacko, Thomas; Cingi, Cemal; Ciprandi, Giorgio; Corey, Jacquelynne; Cox, Linda S.; Creticos, Peter Socrates; Custovic, Adnan; Damask, Cecelia; DeConde, Adam; DelGaudio, John M.; Ebert, Charles S.; Eloy, Jean Anderson; Flanagan, Carrie E.; Fokkens, Wytske J.; Franzese, Christine; Gosepath, Jan; Halderman, Ashleigh; Hamilton, Robert G.; Hoffman, Hans Jürgen; Hohlfeld, Jens M.; Houser, Steven M.; Hwang, Peter H.; Incorvaia, Cristoforo; Jarvis, Deborah; Khalid, Ayesha N.; Kilpeläinen, Maritta; Kingdom, Todd T.; Krouse, Helene; Larenas-Linnemann, Desiree; Laury, Adrienne M.; Lee, Stella E.; Levy, Joshua M.; Luong, Amber U.; Marple, Bradley F.; McCoul, Edward D.; McMains, K. Christopher; Melén, Erik; Mims, James W.; Moscato, Gianna; Mullol, Joaquim; Nelson, Harold S.; Patadia, Monica; Pawankar, Ruby; Pfaar, Oliver; Platt, Michael P.;:
International consensus statement on allergy and rhinology: Allergic rhinitis
International forum of allergy & rhinology, Vol.8 (2018), No.2, pp.108-352
info:doi/10.1002/alr.22073
Fraunhofer ITEM


Schwarz, Katharina; Koch, Wolfgang; Walter, Dorothee:
Investigation into pulmonary absorption using a combination of the ex vivo model of isolated perfused rat lungs and a simple PK model. (Society of Toxicology (Annual Meeting) <57, 2018, San Antonio/Tex.>)
The Toxicologist, Vol.162 (2018), No.1, Late-Breaking Supplement, pp.146-147, Abstract 3532
Fraunhofer ITEM


Schwotzer, Daniela; Schaudien, Dirk; Rittinghausen, Susanne; Meyer-Plath, Asmus; Eckert, V.; Leonhardt, A.; Creutzenberg, Otto H.; Gebel, Thomas:
Investigations on classification and mechanisms of MWCNT-Induced carcinogenicity. (Society of Toxicology (Annual Meeting) <57, 2018, San Antonio/Tex.>)
The Toxicologist, Vol.162 (2018), No.1, pp.407, Abstract PS 2687
Fraunhofer ITEM



Investigations on the Toxicity of CeO2 Nanoparticles after Subchronic Inhalation of Low Doses
Hannover, Tierärztliche Hochschule, Diss., 2018
Fraunhofer ITEM


Tschernig, Thomas; Pabst, Reinhard; Prenzler, Frauke; Rittinghausen, Susanne; Braun, Armin; Hohlfeld, Jens M.:
Isolated aggregates of lymphoid cells in the inner bronchial wall in asthma patients
Cell and tissue research, Vol.374 (2018), No.2, pp.423-425
info:doi/10.1007/s00441-018-2936-5
Fraunhofer ITEM


Lüke, Florian; Blazquez, Raquel; Yamaci, Rezan Fahrioglu; Lu, Xin; Pregler, Benedikt; Hannus, Stefan; Menhart, Karin; Hellwig, Dirk; Wester, Hans-Jürgen; Kropf, Saskia; Heudobler, Daniel; Grosse, Jirka; Moosbauer, Jutta; Hutterer, Markus; Hau, Peter; Riemenschneider, Markus J.; Bayerlová, Michaela; Bleckmann, Annalen; Polzer, Bernhard; Beißbarth, Tim; Klein, Christoph A.; Pukrop, Tobias:
Isolated metastasis of an EGFR-L858R-mutated NSCLC of the meninges: The potential impact of CXCL12/CXCR4 axis in EGFRmut NSCLC in diagnosis, follow-up and treatment
OncoTarget, Vol.9 (2018), No.27, pp.18844-18857
urn:nbn:de:0011-n-5255262
info:doi/10.18632/oncotarget.24787
Volltext
Fraunhofer ITEM


Brüggemann, Maria; Licht, Oliver; Fetter, Éva; Teigeler, Matthias; Schäfers, Christoph; Eilebrecht, Elke:
Knotting nets. Molecular junctions of interconnecting endocrine axes identified by application of the adverse outcome pathway (AOP) concept
Environmental toxicology and chemistry, Vol.37 (2018), No.2, pp.318-328
urn:nbn:de:0011-n-4701436
info:doi/10.1002/etc.3995
Volltext
Fraunhofer IME IME-PUB-1708
Fraunhofer ITEM


Burg, Dominic; Schofield, James P.R.; Brandsma, Joost; Staykova, Doroteya; Folisi, Caterina; Bansal, Aruna T.; Nicholas, Ben; Xian, Yang; Rowe, Anthony; Corfield, Julie; Wilson, Susan J.; Ward, Jonathan A.; Lutter, René; Fleming, Louise; Shaw, Dominick E.; Bakke, Per S.; Caruso, Massimo; Dahlén, Sven-Erik; Fowler, Stephen J.; Hashimoto, Simone; Horvath, Ildiko; Howarth, Peter; Krug, Norbert; Montuschi, Paolo; Sanak, Marek; Sandström, Thomas; Singer, Florian; Sun, Kai; Pandis, Ioannis; Auffray, Charles; Sousa, Ana R.; Adcock, Ian M.; Chung, Kian F.; Sterk, Peter J.; Djukanovic, Ratko; Skipp, Paul J.:
Large-Scale Label-Free Quantitative Mapping of the Sputum Proteome
Journal of proteome research, Vol.17 (2018), No.6, pp.2072-2091
info:doi/10.1021/acs.jproteome.8b00018
Fraunhofer ITEM


Brandsma, Joost; Goss, Victoria M.; Yang, Xian; Bakke, Per S.; Caruso, Massimo; Chanez, Pascal; Dahlén, Sven-Erik; Fowler, Stephen J.; Horváth, Ildikó; Krug, Norbert; Montuschi, Paolo; Sanak, Marek; Sandström, Thomas; Shaw, Dominick E.; Chung, Kian Fan; Singer, Florian; Fleming, Louise J.; Sousa, Ana R.; Pandis, Ioannis; Bansal, Aruna T.; Sterk, Peter J.; Djukanović, Ratko; Postle, Anthony D.:
Lipid phenotyping of lung epithelial lining fluid in healthy human volunteers
Metabolomics, Vol.14 (2018), No.10, Art. 123, 12 pp.
urn:nbn:de:0011-n-5240417
info:doi/10.1007/s11306-018-1412-2
Volltext
Fraunhofer ITEM


Lindner, Karina; Webering, Sina; Ströbele, Michael; Bockhorn, Henning; Hansen, Tanja; König, Peter; Fehrenbach, Heinz:
Low dose carbon black nanoparticle exposure does not aggravate allergic airway inflammation in mice irrespective of the presence of surface polycyclic aromatic hydrocarbons
Nanomaterials, Vol.8 (2018), No.4, Art. 213, 18 pp.
urn:nbn:de:0011-n-4976209
info:doi/10.3390/nano8040213
Volltext
Fraunhofer ITEM


Portillo, J.; Gotzmann, G.; Schönfelder, J.; Rögner, F.-H.; Wronski, S.; Müller, M.; Kohl, Y; Gorjup, E.:
Low-energy electron beam sterilization for medical technical applications. (Society of Vacuum Coaters (Annual Technical Conference) <60, 2017, Providence/RI>)
Lampert, C.M.: Society of Vacuum Coaters. 60th Annual Technical Conference: Providence, USA, 29. April - 04. Mai 2017. Albuquerque: SVC, 2018, 7 pp.
info:doi/10.14332/svc17.proc.42908
Fraunhofer FEP
Fraunhofer ITEM


Gotzmann, G.; Portillo, J.; Wronski, S.; Kohl, Y; Gorjup, E.; Schuck, H.; Rögner, F.-H.; Müller, M.; Chaberny, I.F.; Schönfelder, J.; Wetzel, C.:
Low-energy electron-beam treatment as alternative for on-site sterilization of highly functionalized medical products - a feasibility study
Radiation physics and chemistry, Vol.150 (2018), pp.9-19
info:doi/10.1016/j.radphyschem.2018.04.008
Fraunhofer FEP
Fraunhofer ITEM
Fraunhofer IBMT


Hohlfeld, Jens M.; Vogel-Claussen, Jens; Biller, Heike; Berliner, Dominik; Berschneider, Korbinian; Tillmann, Hanns-Christian; Hiltl, Simone; Bauersachs, Johann; Welte, Tobias:
Lung deflation and improvement of cardiac end-diastolic volumes with indacaterol/glycopyrronium reduce dyspnea and improve health status in hyperinflated COPD patients: The CLAIM study. (American Thoracic Society (ATS International Conference) <2018, San Diego/Calif.>)
American Journal of Respiratory and Critical Care Medicine, Vol.197 (2018), Abstract A4244
Fraunhofer ITEM


Hohlfeld, Jens; Vogel-Claussen, Jens; Biller, Heike; Berliner, Dominik; Berschneider, Korbinian; Tillmann, Hanns-Christian; Hiltl, Simone; Bauersachs, Johann; Welte, Tobias:
Lungenentblähung mit Indacaterol/Glycopyrronium verbessert die kardiale Funktion bei COPD Patienten: Die CLAIM Studie. (Deutsche Gesellschaft für Pneumologie und Beatmungsmedizin (Kongress) <59, 2018, Dresden>)
Pneumologie, Vol.72 (2018), No.S01, pp.S5-S6
info:doi/10.1055/s-0037-1619129
Fraunhofer ITEM


Hohlfeld, Jens M.; Vogel-Claussen, Jens; Biller, Heike; Berliner, Dominik; Berschneider, Korbinian; Tillmann, Hanns-Christian; Hiltl, Simone; Bauersachs, Johann; Welte, Tobias:
Lungenentblähung mit Indacaterol/Glycopyrronium verbessert die kardiale Funktion von COPD Patienten: Die CLAIM Studie. (Deutsche Gesellschaft für Innere Medizin (Kongress) <124, 2018, Mannheim>)
Der Internist, Vol.59 (2018), Supplement 1, pp.S50-S51
Fraunhofer ITEM


Schaudien, D.; Harleman, J.H.; Bouallala, F.; Kuper, C.F.:
Lymphoid Tissue and Pathological Influences of Toxicants
McQueen, C.: Comprehensive Toxicology. Vol. 11: Immune System Toxicology. Saint Louis: Elsevier Science, 2018, pp. 322-342
info:doi/10.1016/B978-0-08-100601-6.01990-6
Fraunhofer ITEM


Fayyad, Adnan; Lapp, Stefanie; Risha, Engy; Pfankuche, Vanessa M.; Rohn, Karl; Barthel, Yvonne; Schaudien, Dirk; Baumgärtner, Wolfgang; Puff, Christina:
Matrix metalloproteinases expression in spontaneous canine histiocytic sarcomas and its xenograft model
Veterinary immunology and immunopathology, Vol.198 (2018), pp.54-64
info:doi/10.1016/j.vetimm.2018.03.002
Fraunhofer ITEM


Ehrmann, Maximilian; Mutius, Erika von; Hansen, Gesine; Kopp, Matthias; Hohlfeld, Jens M.; Holz, Olaf; Fuchs, Oliver:
Measurement of volatile organic compounds in exhaled breath of children of the ALL Age Asthma Cohort. (European Respiratory Society (ERS International Congress) <2018, Paris>)
European Respiratory Journal, Vol.52 (2018), Supplement 62, Abstract PA5025
info:doi/10.1183/13993003.congress-2018.PA5025
Fraunhofer ITEM


Alahmadi, Fahad; Simpson, Andrew; Gomez, Christina; Wheelock, Craig; Shaw, Dominick E.; Fleming, Louise; Roberts, Graham; Riley, John; Bates, Stewart; Sousa, Ana R.; Knowles, Richard; Bansal, Aruna T.; Corfield, Julie; Pandis, Ioannis; Sun, Kai; Bakke, Per; Caruso, Massimo; Chanez, Pascal; Dahlen, Babro; Horváth, Ildikó; Krug, Norbert; Montuschi, Paolo; Sandstrom, Thomas; Singer, Florian; Wagers, Scott; Adcock, Ian M.; Djukanović, Ratko; Chung, Kian Fan; Sterk, Peter J.; Dahlén, Sven-Erik; Fowler, Stephen J.:
Measures of adherence in patients with severe asthma prescribed systemic steroids in the U-BIOPRED cohort. (European Respiratory Society (ERS International Congress) <2018, Paris>)
European Respiratory Journal, Vol.52 (2018), Supplement 62, Abstract PA3992
info:doi/10.1183/13993003.congress-2018.PA3992
Fraunhofer ITEM


Dehmel, Susann; Jiménez Delgado, Sharon Melissa; Obernolte, Helena; Reamon-Buettner, Stella Marie; Jonigk, Danny; Pfennig, Olaf; Braubach, Peter; Warnecke, Gregor; Fieguth, Hans-Gerd; Sewald, Katherina; Braun, Armin:
Mechanism of NK1-mediated bronchoconstriction in passively sensitized human lung tissue. (European Respiratory Society (ERS International Congress) <2018, Paris>)
European Respiratory Journal, Vol.52 (2018), Supplement 62, Abstract PA1120
info:doi/10.1183/13993003.congress-2018.PA1120
Fraunhofer ITEM


Pohlmann, Gerhard; Ramazanoglu, Mehmet:
Messgerät und Verfahren zum Betimmen einer maximalen Inhalationsleistung einer Person
2018
Fraunhofer ITEM


Feldmann, Jörg; Blümlein, Katharina; Krupp, Eva Maria; Müller, Martin; Wood, Barry A.:
Metallomics Study in Plants Exposed to Arsenic, Mercury, Selenium and Sulphur
Arruda, M.A.Z.: Metallomics. The Science of Biometals. Cham: Springer International Publishing, 2018. (Advances in experimental medicine and biology 1055), pp. 67-100
info:doi/10.1007/978-3-319-90143-5_4
Fraunhofer ITEM


Schwarz, Katharina; Pappa, Gerlinde; Miertsch, Heike; Scheel, Julia; Koch, Wolfgang:
A methodology for the assessment of inhalation exposure to aluminium from antiperspirant sprays
Archives of toxicology, Vol.92 (2018), No.4, pp.1383-1392
info:doi/10.1007/s00204-017-2151-2
Fraunhofer ITEM


Ökmen, Bilal; Mathow, Daniel; Hof, Alexander; Lahrmann, Urs; Aßmann, Daniela; Doehlemann, Gunther:
Mining the effector repertoire of the biotrophic fungal pathogen Ustilago hordei during host and non-host infection
Molecular Plant Pathology, Vol.19 (2018), No.12, pp.2603-2622
urn:nbn:de:0011-n-5376822
info:doi/10.1111/mpp.12732
Volltext
Fraunhofer ITEM


Konzok, Sebastian; Dehmel, Susann; Werno, Christian; Braubach, Peter; Warnecke, Gregor; Zardo, Patrick; Jonigk, Danny; Pfennig, Olaf; Fieguth, Hans-Gerd; Polzer, Bernhard; Weidele, Kathrin; Klein, Christoph A.; Braun, Armin; Sewald, Katherina:
Modulation of tumor-microenvironmental factors and cancer growth in co-cultures of fresh human lung tissue and patient-derived cancer cells. (European Respiratory Society (ERS International Congress) <2018, Paris>)
European Respiratory Journal, Vol.52 (2018), Supplement 62, Abstract PA2851
info:doi/10.1183/13993003.congress-2018.PA2851
Fraunhofer ITEM


Laux, Peter; Tentschert, Jutta; Riebeling, Christian; Braeuning, Albert; Creutzenberg, Otto; Epp, Astrid; Fessard, Valérie; Haas, Karl-Heinz; Haase, Andrea; Hund-Rinke, Kerstin; Jakubowski, Norbert; Kearns, Peter; Lampen, Alfonso; Rauscher, Hubert; Schoonjans, Reinhilde; Störmer, Angela; Thielmann, Axel; Mühle, Uwe; Luch, Andreas:
Nanomaterials: Certain aspects of application, risk assessment and risk communication
Archives of toxicology, Vol.92 (2018), No.1, pp.121-141
urn:nbn:de:0011-n-4776880
info:doi/10.1007/s00204-017-2144-1
Volltext
Fraunhofer ISC
Fraunhofer ITEM
Fraunhofer IVV 3604
Fraunhofer ISI
Fraunhofer IKTS
Fraunhofer IME IME-PUB-1801


Prasse, Antje; Jäger, Benedikt; Plappert, Linda; Kraus, Kim; Wollin, Lutz:
A new humanized mouse model for idiopathic pulmonary fibrosis and effects of nintedanib treatment. (European Respiratory Society (ERS International Congress) <2018, Paris>)
European Respiratory Journal, Vol.52 (2018), Supplement 62, Abstract OA5363
info:doi/10.1183/13993003.congress-2018.OA5363
Fraunhofer ITEM


Konerding, W.S.; Froriep, Ulrich P.; Kral, A.; Baumhoff, P.:
New thin-film surface electrode array enables brain mapping with high spatial acuity in rodents
Scientific Reports, Vol.8 (2018), No.1, Art. 3825, 14 pp.
info:doi/10.1038/s41598-018-22051-z
Fraunhofer ITEM


Prasse, Antje; Engelhard, P.; Plappert, Linda; Hornung, V.; Bauernfeind, F.; Jäger, Benedikt:
The NLRP3 inflammasome and IL-1β pathway have a pivotal role in granuloma formation of sarcoidosis. (American Thoracic Society (ATS International Conference) <2018, San Diego/Calif.>)
American Journal of Respiratory and Critical Care Medicine, Vol.197 (2018), Abstract A4492
Fraunhofer ITEM


Brändli-Baiocco, Annamaria; Balme, Emmanuelle; Bruder, Marc; Chandra, Sundeep; Hellmann, Jürgen; Hoenerhoff, Mark J.; Kambara, Takahito; Landes, Christian; Lenz, Barbara; Mense, Mark; Rittinghausen, Susanne; Satoh, Hiroshi; Schorsch, Frédéric; Seeliger, Frank; Tanaka, Takuji; Tsuchitani, Minoru; Wojcinski, Zbigniew; Rosol, Thomas J.:
Nonproliferative and proliferative lesions of the rat and mouse endocrine system
Journal of toxicologic pathology, Vol.31 (2018), Supplement 3, pp.1S-95S
urn:nbn:de:0011-n-5124974
info:doi/10.1293/tox.31.1S
Volltext
Fraunhofer ITEM


Ramos, Meg Ferrell; Baker, Julia F.; Atzpodien, Elke-Astrid; Bach, Ute; Brassard, Jacqueline; Cartwright, James; Farman, Cynthia; Fishman, Cindy; Jacobsen, Matt; Junker-Walker, Ursula; Kuper, Frieke; Moreno, Maria Cecilia Rey; Rittinghausen, Susanne; Schafer, Ken; Tanaka, Kohji; Teixeira, Leandro; Yoshizawa, Katsuhiko; Zhang, Hui:
Nonproliferative and proliferative lesions of the ratand mouse special sense organs(Ocular [eye and glands], olfactory and otic)
Journal of toxicologic pathology, Vol.31 (2018), No.3 Suppl., pp.97S-214S
urn:nbn:de:0011-n-5155333
info:doi/10.1293/tox.31.97S
Volltext
Fraunhofer ITEM


Hücker, Sarah M.; Vanderhaeghen, Sonja; Abellan-Schneyder, Isabel; Wecko, Romy; Simon, Svenja; Scherer, Siegfried; Neuhaus, Klaus:
A novel short L-arginine responsive protein-coding gene (laoB) antiparallel overlapping to a CadC-like transcriptional regulator in Escherichia coli O157:H7 Sakai originated by overprinting
BMC evolutionary biology. Online journal, Vol.18 (2018), Art.21, 14 pp.
info:doi/10.1186/s12862-018-1134-0
Fraunhofer ITEM


Wiegand, C.; Hansen, T.; Köhnlein, J.; Exner, I.; Damisch-Pohl, M.; Schott, P.; Krühner-Wiesenberger, U.; Hipler, U.-C.; Pohlen, E.:
Optimized protocol for the biocompatibility testing of compression stockings and similar products with close skin contact in vitro
Journal of the Textile Institute : JOTI, Vol.109 (2018), No.7, pp.891-902
info:doi/10.1080/00405000.2017.1383640
Fraunhofer ITEM


Kilias, Antje; Canales, Andres; Froriep, Ulrich P.; Park, Seongjun; Egert, Ulrich; Anikeeva, Polina:
Optogenetic entrainment of neural oscillations with hybrid fiber probes
Journal of neural engineering, Vol.15 (2018), No.5, Art. 056006, 14 pp.
info:doi/10.1088/1741-2552/aacdb9
Fraunhofer ITEM


Hekking, Pieter-Paul; Loza, Matt J.; Pavlidis, Stelios; Meulder, Bertrand de; Lefaudeux, Diane; Baribaud, Fred; Auffray, Charles; Wagener, Ariane H.; Brinkman, Paul; Lutter, René; Bansal, Aruna T.; Sousa, Ana R.; Bates, Steve A.; Pandis, Yannis; Fleming, Louise J.; Shaw, Dominique E.; Fowler, Stephen J.; Guo, Y.; Meiser, Andrea; Sun, Kai; Corfield, Julie; Howarth, Peter H.; Bel, Elisabeth H.; Adcock, Ian M.; Chung, Kian Fan; Djukanović, Ratko; Sterk, Peter J.:
Pathway discovery using transcriptomic profiles in adult-onset severe asthma
The journal of allergy and clinical immunology : JACI, Vol.141 (2018), No.4, pp.1280-1290
info:doi/10.1016/j.jaci.2017.06.037
Fraunhofer ITEM


Rogol, Alan D.; Tkachenko, Natalia; Badorrek, Philipp; Hohlfeld, Jens M.; Bryson, Nathan:
Phase 1 pharmacokinetics and phase 3 efficacy of testosterone nasal gel in subjects with seasonal allergies
The Canadian journal of urology, Vol.12 (2018), No.7, pp.E349-E356
info:doi/10.5489/cuaj.4898
Fraunhofer ITEM


Pardali, Katerina; Winkler, Carla; Hochdorfer, T.; Cavallin, A.; Hasselberg, A.; Vaarala, O.; Müller, Meike; Lüer, Katrin:
Phenotypic characterization of blood and lung ILC2 in asthmatics undergoing segmental allergen provocation. (American Thoracic Society (ATS International Conference) <2018, San Diego/Calif.>)
American Journal of Respiratory and Critical Care Medicine, Vol.197 (2018), Art. A5966
info:doi/10.1164/ajrccm-conference.2018
Fraunhofer ITEM


Winkler, Daniel Sandro; Escher, Sylvia E. (Betr.); Esch, Christina (Betr.) :
Physiologisch basierte toxikokinetische (PBTK) Modellierung zur Aufnahme von Chemikalien/Aerosolen über die Lunge
Hannover, Univ., Master Thesis, 2018
Fraunhofer ITEM


Creutzenberg, Otto H.; Ziemann, Christina; Oliveira, H.; Farcal, L.; Burla, S.:
Platox in vitro and in vivo investigations (28-day inhalation) to generate valid toxicity data for risk assessment of carbon-based nanoplatelets. (Society of Toxicology (Annual Meeting) <57, 2018, San Antonio/Tex.>)
The Toxicologist, Vol.162 (2018), No.1, pp.422
Fraunhofer ITEM


Creutzenberg, Otto H.; Ziemann, Christina; Schaudien, Dirk; Oliveira, Helena; Farcal, Lucian:
The PLATOX project: Combining in vitro and in vivo investigations to generate valid toxicity data for risk assessment of graphene nanoplatelets. (European Societies of Toxicology (EUROTOX Congress) <54, 2018, Brussels>)
Toxicology letters, Vol.295 (2018), Supplment 1, pp.S205, Abstract P17-06
info:doi/10.1016/j.toxlet.2018.06.902
Fraunhofer ITEM


Philipp, Friederike; Selich, Anton; Rothe, Michael; Hoffmann, Dirk; Rittinghausen, Susanne; Sewald, Katherina; Braun, Armin; Schambach, Axel:
Polyclonal development of hematopoiesis in teratomas generated with human induced pluripotent stem cells. (International Society for Experimental Hematology (ISEH Annual Scientific Meeting) <47, 2018, Los Angeles/Calif.>)
Experimental Hematology, Vol.64 (2018), Supplement, pp.S93
info:doi/10.1016/j.exphem.2018.06.118
Fraunhofer ITEM


Escher, Sylvia E.; Tolosa Pardo, L.; Maclennan, R.; Stöber, R.; Limonciel, A.; Fisher, C.; Brotzmann, K.; Vugt-Lussenburg, B.M. van; Vrijenhoek, N.G.; Gräpel, R.:
Prediction of microvesicular liver steatosis: a read-across case study with branched carboxylic acids. (Society of Toxicology (Annual Meeting) <57, 2018, San Antonio/Tex.>)
The Toxicologist, Vol.162 (2018), No.1, pp.521-522, Abstract PS 3157
Fraunhofer ITEM


Gosemann, Jan-Hendrik; Friedmacher, Florian; Hofmann, Alejandro; Zimmer, Julia; Kuebler, Joachim F.; Rittinghausen, Susanne; Suttkus, Anne; Lacher, Martin; Alvarez, Luis; Corcionivoschi, Nicolae; Puri, Prem:
Prenatal treatment with rosiglitazone attenuates vascular remodeling and pulmonary monocyte influx in experimental congenital diaphragmatic hernia
PLoS one. Online journal, Vol.13 (2018), No.11, Art. e0206975, 14 pp.
info:doi/10.1371/journal.pone.0206975
Fraunhofer ITEM


Baric, Valentin; Grossmann, Henrike Katharina; Koch, Wolfgang; Mädler, Lutz:
Quantitative characterization of mixing in multicomponent nanoparticle aggregates
Particle and particle systems characterization, Vol.35 (2018), No.10, Art. 1800177, 13 pp.
info:doi/10.1002/ppsc.201800177
Fraunhofer ITEM


Renne, Julius; Biller, Heike; Gutberlet, Marcel; Czerner, Christoph; Schiwek, Marilisa; Hohl, Kathrin; Risse, Frank; Sarno, Maria; Gupta, Abhya; Hohlfeld, Jens; Vogel-Claussen, Jens:
Regional detection of edema following segmental LPS challenge using functional MR imaging. (European Respiratory Society (ERS International Congress) <2018, Paris>)
European Respiratory Journal, Vol.52 (2018), Supplement 62, Abstract OA3798
info:doi/10.1183/13993003.congress-2018.OA3798
Fraunhofer ITEM


Hesse, Susanne; Hahn, Stefan; Lamb, Judith; Basinas, Ioannis; Apsley, Andrew; Tongeren, Martie van; Urbanus, J.; Pizzella, G.; Banton, M.; Dudzina, T.; Tibaldi, R.; Geudens, B.; Jones, R.; Ketelslegers, H.; Trantallidi, M.:
Review of Tier 1 workplace exposure estimates for petroleum substances in REACH dossiers
Brussels: Concawe, 2018
(Concawe report 13)
ISBN 978-2-87567-094-6
Fraunhofer ITEM


Krug, Norbert; Hohlfeld, Jens M.; Aliprantis, Antonios; Carayannopoulos, Leonidas; Bautmans, An; Robberechts, Martine; Lepeleire, Inge de; Ziehr, Holger; Singh, Dave; Diamant, Zuzana; Yang, Shan; Fitch, Neil; Thornton, Bob; Sterk, Peter J.; Lutter, René:
Rhinovirus challenge in asthmatics and healthy volunteers to evaluate the safety and appropriate dose of a GMP human rhinovirus 16 preparation for challenge studies in mild-moderate asthmatics taking ICS. (European Respiratory Society (ERS International Congress) <2018, Paris>)
European Respiratory Journal, Vol.52 (2018), Supplement 62, Abstract PA4406
info:doi/10.1183/13993003.congress-2018.PA4406
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment 2,4-dimethylbenzyl acetate, CAS Registry Number 62346-96-7
Food and Chemical Toxicology : FCT, Vol.115 (2018), Supplement 1, pp.S80-S89
info:doi/10.1016/j.fct.2017.12.012
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment 2-Benzylheptanol, CAS Registry Number 92368-90-6
Food and Chemical Toxicology : FCT, Vol.115 (2018), Supplement 1, pp.S231-S240
info:doi/10.1016/j.fct.2018.01.040
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment 2-methyl-trans-2-butenoic acid, CAS Registry Number 80-59-1
Food and Chemical Toxicology : FCT, Vol.118 (2018), pp.S1-S7
info:doi/10.1016/j.fct.2018.05.048
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment 5,8-Methano-2H-1-benzopyran-2-one, 6- ethylideneoctahydro-, CAS Registry Number 69486-14-2
Food and Chemical Toxicology : FCT, Vol.115 (2018), Supplement 1, pp.S183-S189
info:doi/10.1016/j.fct.2018.01.008
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Dekant, W.; Fryer, A.D.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Wahler, J.:
RIFM fragrance ingredient safety assessment β-Patchoulene, CAS Registry Number 514-51-2
Food and Chemical Toxicology : FCT, Vol.115 (2018), Supplement 1, pp.S256-S263
info:doi/10.1016/j.fct.2018.03.053
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment benzyl 2,2-dimethylpropanoate, CAS Registry Number 2094-69-1
Food and Chemical Toxicology : FCT, Vol.115 (2018), Supplement 1, pp.S96-S106
info:doi/10.1016/j.fct.2017.12.048
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment cyclohexanecarboxylic acid, CAS Registry Number 98-89-5
Food and Chemical Toxicology : FCT, Vol.115 (2018), Supplement 1, pp.S248-S255
info:doi/10.1016/j.fct.2018.03.026
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment diethyl succinate, CAS Registry Number 123-25-1
Food and Chemical Toxicology : FCT, Vol.115 (2018), Supplement 1, pp.S114-S123
info:doi/10.1016/j.fct.2017.12.050
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment dihydro-β-terpinyl acetate, CAS Registry Number 26252-11-9
Food and Chemical Toxicology : FCT, Vol.115 (2018), Supplement 1, pp.S206-S213
info:doi/10.1016/j.fct.2018.01.037
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment Dimethyl succinate, CAS Registry Number 106-65-0
Food and Chemical Toxicology : FCT, Vol.115 (2018), Supplement 1, pp.S124-S132
info:doi/10.1016/j.fct.2017.12.056
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; BruzE, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; DekanT, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; la Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT p-Methylanisole, CAS Registry Number 104-93-8
Food and Chemical Toxicology : FCT, Vol.115 (2018), Supplement 1, pp.S241-S247
info:doi/10.1016/j.fct.2018.01.041
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment phenethyl isovalerate, CAS Registry Number 140-26-1
Food and Chemical Toxicology : FCT, Vol.115 (2018), Supplement 1, pp.S162-S172
info:doi/10.1016/j.fct.2018.01.006
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; Cava, S.L.A.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT phenylethyl 2-methylbutyrate, CAS Registry Number 24817-51-4
Food and Chemical Toxicology : FCT, Vol.115 (2018), Supplement 1, pp.S214-S224
info:doi/10.1016/j.fct.2018.01.038
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, 1,1-diethoxyisooctane, CAS Registry Number 69178-43-4
Food and Chemical Toxicology : FCT, Vol.115 (2018), Supplement 1, pp.S199-S205
info:doi/10.1016/j.fct.2018.01.032
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 1,2,3,4,5,6,7,8,9,10-decahydro-5,9-methanobenzocycloocten-11-one, CAS Registry Number 22690-27-3
Food and Chemical Toxicology : FCT, Vol.118 (2018), Supplement 1, pp.S15-S21
info:doi/10.1016/j.fct.2018.05.065
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 1,3-Benzodioxole-5-propanol, α-methyl-, 5-acetate, CAS Registry Number 68844-96-2
Food and Chemical Toxicology : FCT, Vol.118 (2018), Supplement 1, pp.S170-S177
info:doi/10.1016/j.fct.2018.07.006
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 1,3-dimethylbut-3-enyl isobutyrate, CAS Registry Number 80118-06-5
Food and Chemical Toxicology : FCT, Vol.122 (2018), Supplement 1, pp.S18-S23
info:doi/10.1016/j.fct.2018.08.016
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 1-(3,3-dimethylbicyclo[2.2.1]hept-2-yl)ethane-1-one, CAS Registry Number 42370-07-0
Food and Chemical Toxicology : FCT, Vol.122 (2018), Supplement 1, pp.S117-S122
info:doi/10.1016/j.fct.2018.08.040
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT, 1-Methyl-2-(1-methylpropyl)cyclohexyl acetate, CAS Registry Number 72183-75-6
Food and Chemical Toxicology : FCT, Vol.118 (2018), Supplement 1, pp.S94-S102
info:doi/10.1016/j.fct.2018.06.042
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT, 1-Oxaspiro[4.5]decan-2-one, 8-(1-methylethyl)-, trans-, CAS Registry Number 4625-90-5
Food and Chemical Toxicology : FCT, Vol.118 (2018), Supplement 1, pp.S114-S122
info:doi/10.1016/j.fct.2018.06.044
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 1-oxaspiro[4.5]decan-2-one, 8-methyl-, CAS Registry Number 94201-19-1
Food and Chemical Toxicology : FCT, Vol.118 (2018), Supplement 1, pp.S123-S131
info:doi/10.1016/j.fct.2018.06.045
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT, 2,6-Dimethylocta-2,4,6-triene, CAS Registry Number 673-84-7
Food and Chemical Toxicology : FCT, Vol.118 (2018), Supplement 1, pp.S147-S155
info:doi/10.1016/j.fct.2018.06.048
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 2-ethylhexyl acetate, CAS Registry Number 103-09-3
Food and Chemical Toxicology : FCT, Vol.122 (2018), Supplement 1, pp.S175-S184
info:doi/10.1016/j.fct.2018.08.048
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 2-Hexylcyclopentanone, CAS Registry Number 13074-65-2
Food and Chemical Toxicology : FCT, Vol.118 (2018), Supplement 1, pp.S77-S83
info:doi/10.1016/j.fct.2018.06.036
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT, [2-Isopropoxyethyl]benzene, CAS Registry Number 68039-47-4
Food and Chemical Toxicology : FCT, Vol.118 (2018), Supplement 1, pp.S193-S200
info:doi/10.1016/j.fct.2018.07.037
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT, 2-Methyl-2-hepten-6-ol, CAS Registry Number 1569-60-4
Food and Chemical Toxicology : FCT, Vol.118 (2018), Supplement 1, pp.S218-S225
info:doi/10.1016/j.fct.2018.07.040
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 2-methylhexanoic acid, CAS Registry Number 4536-23-6
Food and Chemical Toxicology : FCT, Vol.118 (2018), Supplement 1, pp.S201-S209
info:doi/10.1016/j.fct.2018.07.038
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, 2-methylundecanal dimethyl acetal, CAS Registry Number 68141-17-3
Food and Chemical Toxicology : FCT, Vol.115 (2018), Supplement 1, pp.S90-S95
info:doi/10.1016/j.fct.2017.12.027
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 2-Methylvaleric acid, CAS Registry Number 97-61-0
Food and Chemical Toxicology : FCT, Vol.118 (2018), Supplement 1, pp.S59-S68
info:doi/10.1016/j.fct.2018.06.034
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM Fragrance ingredient safety assessment, 2-nonen-1-ol, CAS registry number 22104-79-6
Food and Chemical Toxicology : FCT, Vol.122 (2018), Supplement 1, pp.S157-S164
info:doi/10.1016/j.fct.2018.08.046
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 2H-Inden-2-one, 1,3-dihydro-, CAS Registry Number 615-13-4
Food and Chemical Toxicology : FCT, Vol.122 (2018), Supplement 1, pp.S151-S156
info:doi/10.1016/j.fct.2018.08.045
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 3-(cis-3-hexenyloxy)propanenitrile, CAS Registry Number 142653-61-0
Food and Chemical Toxicology : FCT, Vol.122 (2018), Supplement 1, pp.S468-S474
info:doi/10.1016/j.fct.2018.10.009
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, 3-methyl-1-pentanol, CAS Registry Number 589-35-5
Food and Chemical Toxicology : FCT, Vol.115 (2018), Supplement 1, pp.S26-S34
info:doi/10.1016/j.fct.2017.11.036
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Bhatia, S.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; Kromidas, L.; La Cava, S.; Lalko, J.F.; Lapczynski, A.; Liebler, D.C.; Miyachi, Y.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Politano, V.T.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.; Wall, B.; Wilcox, D.K.:
RIFM fragrance ingredient safety assessment, 3-methyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)pent-4-en-2-ol, CAS Registry Number 67801-20-1
Food and Chemical Toxicology : FCT, Vol.115 (2018), Supplement 1, pp.S143-S152
info:doi/10.1016/j.fct.2017.12.065
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, 3-Methylbutanal diethyl acetal, CAS Registry Number 3842-03-3
Food and Chemical Toxicology : FCT, Vol.115 (2018), Supplement 1, pp.S107-S113
info:doi/10.1016/j.fct.2017.12.049
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, 3-tert-butylcyclohexyl acetate, CAS Registry Number 31846-06-7
Food and Chemical Toxicology : FCT, Vol.115 (2018), Supplement 1, pp.S9-S17
info:doi/10.1016/j.fct.2017.11.034
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 3a,4,5,6,7,7a-hexahydro-4,7-methano-1H-inden-5-yl pivalate, CAS Registry Number 68039-45-2
Food and Chemical Toxicology : FCT, Vol.122 (2018), Supplement 1, pp.S521-S530
info:doi/10.1016/j.fct.2018.10.015
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 4′-methylacetophenone, CAS Registry Number 122-00-9
Food and Chemical Toxicology : FCT, Vol.122 (2018), Supplement 1, pp.S75-S83
info:doi/10.1016/j.fct.2018.08.023
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT, 4,8-Dimethyl-3-7-nonadien-2-ol, CAS Registry Number 67845-50-5
Food and Chemical Toxicology : FCT, Vol.118 (2018), Supplement 1, pp.S178-S184
info:doi/10.1016/j.fct.2018.07.008
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; Cava, S.L.A.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, 4-Hexen-1-ol, (4Z)-, CAS Registry Number 928-91-6
Food and Chemical Toxicology : FCT, Vol.115 (2018), Supplement 1, pp.S43-S50
info:doi/10.1016/j.fct.2017.11.038
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 4-pentenoic acid, 2-acetyl-4-methyl-, ethyl ester, CAS Registry Number 20962-70-3
Food and Chemical Toxicology : FCT, Vol.122 (2018), Supplement 1, pp.S123-S128
info:doi/10.1016/j.fct.2018.08.041
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, 5,9-undecadien-2-ol,6,10-dimethyl-,acetate, CAS Registry Number 91482-37-0
Food and Chemical Toxicology : FCT, Vol.118 (2018), Supplement 1, pp.S132-S140
info:doi/10.1016/j.fct.2018.06.046
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, acetal, CAS Registry Number 105-57-7
Food and Chemical Toxicology : FCT, Vol.122 (2018), Supplement 1, pp.S445-S452
info:doi/10.1016/j.fct.2018.09.077
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, acetophenone, CAS Registry Number 98-86-2
Food and Chemical Toxicology : FCT, Vol.118 (2018), Supplement 1, pp.S162-S169
info:doi/10.1016/j.fct.2018.06.050
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, Amylcyclohexyl acetate (mixed isomers), CAS Registry Number 67874-72-0
Food and Chemical Toxicology : FCT, Vol.115 (2018), Supplement 1, pp.S51-S60
info:doi/10.1016/j.fct.2017.11.040
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, β-caryophyllene alcohol, CAS Registry Number 472-97-9
Food and Chemical Toxicology : FCT, Vol.122 (2018), Supplement 1, pp.S566-S572
info:doi/10.1016/j.fct.2018.10.020
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, benzyl formate, CAS Registry Number 104-57-4
Food and Chemical Toxicology : FCT, Vol.115 (2018), pp.S173-S182
info:doi/10.1016/j.fct.2018.01.007
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, benzyl isoamyl ether, CAS Registry Number 122-73-6
Food and Chemical Toxicology : FCT, Vol.118 (2018), Supplement 1, pp.S226-S232
info:doi/10.1016/j.fct.2018.07.041
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, benzyl methyl ether, CAS Registry Number 538-86-3
Food and Chemical Toxicology : FCT, Vol.122 (2018), Supplement 1, pp.S573-S579
info:doi/10.1016/j.fct.2018.10.021
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, bis(hydroxymethyl)tricyclo[5.2.1.02,6]decane, CAS Registry Number 26160-83-8
Food and Chemical Toxicology : FCT, Vol.122 (2018), Supplement 1, pp.S24-S31
info:doi/10.1016/j.fct.2018.08.017
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT, butanoic acid, 3a,4,5,6,7,7a-hexahydro-4,7-methano-1H-indenyl ester, CAS Registry Number 113889-23-9
Food and Chemical Toxicology : FCT, Vol.118 (2018), Supplement 1, pp.S84-S93
info:doi/10.1016/j.fct.2018.06.041
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT, Butyl phenylacetate, CAS Registry Number 122-43-0
Food and Chemical Toxicology : FCT, Vol.118 (2018), Supplement 1, pp.S41-S48
info:doi/10.1016/j.fct.2018.06.032
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, butyrophenone, cas Registry Number 495-40-9
Food and Chemical Toxicology : FCT, Vol.118 (2018), Supplement 1, pp.S32-S40
info:doi/10.1016/j.fct.2018.06.031
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, cis-3-octenyl propionate, CAS Registry Number 94134-03-9
Food and Chemical Toxicology : FCT, Vol.122 (2018), Supplement 1, pp.S129-S137
info:doi/10.1016/j.fct.2018.08.042
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, cis-5-octen-1-ol CAS Registry Number 64275-73-6
Food and Chemical Toxicology : FCT, Vol.115 (2018), Supplement 1, pp.S35-S42
info:doi/10.1016/j.fct.2017.11.037
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, dihydroterpinyl acetate, CAS registry number 58985-18-5
Food and Chemical Toxicology : FCT, Vol.122 (2018), Supplement 1, pp.S47-S56
info:doi/10.1016/j.fct.2018.08.020
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, dodecanal dimethyl acetal, CAS Registry Number 14620-52-1
Food and Chemical Toxicology : FCT, Vol.115 (2018), Supplement 1, pp.S1-S8
info:doi/10.1016/j.fct.2017.11.033
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, dodecanenitrile, CAS Registry Number 2437-25-4
Food and Chemical Toxicology : FCT, Vol.115 (2018), Supplement 1, pp.S153-S161
info:doi/10.1016/j.fct.2018.01.005
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, endo-1,2,3,3-tetramethylbicyclo[2.2.1]heptan-2-ol, CAS Registry Number 28462-85-3
Food and Chemical Toxicology : FCT, Vol.122 (2018), Supplement 1, pp.S461-S467
info:doi/10.1016/j.fct.2018.10.008
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, ethyl phenylacetate, CAS Registry Number 101-97-3
Food and Chemical Toxicology : FCT, Vol.122 (2018), Supplement 1, pp.S192-S200
info:doi/10.1016/j.fct.2018.08.050
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, Fenchone, CAS Registry Number 1195-79-5
Food and Chemical Toxicology : FCT, Vol.122 (2018), Supplement 1, pp.S209-S217
info:doi/10.1016/j.fct.2018.08.052
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, geranic acid, CAS Registry Number 459-80-3
Food and Chemical Toxicology : FCT, Vol.122 (2018), Supplement 1, pp.S68-S74
info:doi/10.1016/j.fct.2018.08.022
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, heptanal dimethyl acetal, CAS Registry Number 10032-05-0
Food and Chemical Toxicology : FCT, Vol.115 (2018), Supplement 1, pp.S72-S79
info:doi/10.1016/j.fct.2017.11.043
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, hexahydro-3H-benzofuran-2-one, CAS Registry Number 6051-03-2
Food and Chemical Toxicology : FCT, Vol.122 (2018), Supplement 1, pp.S90-S98
info:doi/10.1016/j.fct.2018.08.037
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, Hexyl acetate, CAS Registry Number 142-92-7
Food and Chemical Toxicology : FCT, Vol.118 (2018), Supplement 1, pp.S103-S113
info:doi/10.1016/j.fct.2018.06.043
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, hexyl benzoate, CAS Registry Number 6789-88-4
Food and Chemical Toxicology : FCT, Vol.118 (2018), Supplement 1, pp.S69-S76
info:doi/10.1016/j.fct.2018.06.035
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, hexyl formate, CAS Registry Number 629-33-4
Food and Chemical Toxicology : FCT, Vol.122 (2018), Supplement 1, pp.S99-S108
info:doi/10.1016/j.fct.2018.08.038
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, isobutyl benzoate, CAS registry number 120-50-3
Food and Chemical Toxicology : FCT, Vol.122 (2018), Supplement 1, pp.S372-S379
info:doi/10.1016/j.fct.2018.09.032
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, isophorol, CAS Registry Number 470-99-5
Food and Chemical Toxicology : FCT, Vol.122 (2018), Supplement 1, pp.S580-S586
info:doi/10.1016/j.fct.2018.10.022
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, l-menthyl lactate, CAS Registry Number 59259-38-0
Food and Chemical Toxicology : FCT, Vol.115 (2018), Supplement 1, pp.S61-S71
info:doi/10.1016/j.fct.2017.11.041
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, methyl benzoate, CAS Registry Number 93-58-3
Food and Chemical Toxicology : FCT, Vol.122 (2018), Supplement 1, pp.S218-S224
info:doi/10.1016/j.fct.2018.08.053
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM Fragrance ingredient safety assessment, methylheptenol, CAS Registry Number 1335-09-7
Food and Chemical Toxicology : FCT, Vol.118 (2018), Supplement 1, pp.S185-S192
info:doi/10.1016/j.fct.2018.07.009
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, nonane, 1,1-diethoxy-, CAS Registry Number 54815-13-3
Food and Chemical Toxicology : FCT, Vol.118 (2018), Supplement 1, pp.S8-S14
info:doi/10.1016/j.fct.2018.05.064
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, nonyl acetate, CAS Registry Number 143-13-5
Food and Chemical Toxicology : FCT, Vol.122 (2018), Supplement 1, pp.S491-S500
info:doi/10.1016/j.fct.2018.10.012
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; Cava, S.L.A.; Lapczynski, A.; Liebler, D.C.; O'brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, octanal dimethyl acetal, CAS Registry Number 10022-28-3
Food and Chemical Toxicology : FCT, Vol.115 (2018), Supplement 1, pp.S225-S230
info:doi/10.1016/j.fct.2018.01.039
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, octyl butyrate, CAS Registry Number 110-39-4
Food and Chemical Toxicology : FCT, Vol.122 (2018), Supplement 1, pp.S396-S405
info:doi/10.1016/j.fct.2018.09.036
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, p-(2,2-dimethoxyethoxy)toluene, CAS Registry Number 6324-78-3
Food and Chemical Toxicology : FCT, Vol.122 (2018), Supplement 1, pp.S301-S308
info:doi/10.1016/j.fct.2018.08.075
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, p-tert-butylacetophenone, CAS Registry Number 943-27-1
Food and Chemical Toxicology : FCT, Vol.118 (2018), Supplement 1, pp.S210-S217
info:doi/10.1016/j.fct.2018.07.039
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, pentanedioic acid, 1,5-dimethyl ester, CAS Registry Number 1119-40-0
Food and Chemical Toxicology : FCT, Vol.115 (2018), Supplement 1, pp.S190-S198
info:doi/10.1016/j.fct.2018.01.009
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, phenethyl tiglate, CAS Registry Number 55719-85-2
Food and Chemical Toxicology : FCT, Vol.115 (2018), Supplement 1, pp.S133-S142
info:doi/10.1016/j.fct.2017.12.064
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, terpinyl acetate (isomer mixture), CAS Registry number 8007-35-0
Food and Chemical Toxicology : FCT, Vol.122 (2018), Supplement 1, pp.S362-S371
info:doi/10.1016/j.fct.2018.09.031
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT, Terpinyl butyrate, CAS Registry Number 2153-28-8
Food and Chemical Toxicology : FCT, Vol.118 (2018), Supplement 1, pp.S22-S31
info:doi/10.1016/j.fct.2018.06.030
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, terpinyl formate, CAS Registry Number 2153-26-6
Food and Chemical Toxicology : FCT, Vol.122 (2018), Supplement 1, pp.S501-S510
info:doi/10.1016/j.fct.2018.10.013
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, terpinyl propionate, CAS Registry Number 80-27-3
Food and Chemical Toxicology : FCT, Vol.122 (2018), Supplement 1, pp.S316-S326
info:doi/10.1016/j.fct.2018.09.003
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, trans-2-Hexenol, CAS Registry Number 928-95-0
Food and Chemical Toxicology : FCT, Vol.118 (2018), Supplement 1, pp.S49-S58
info:doi/10.1016/j.fct.2018.06.033
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, tricyclodecanyl acetate, CAS Registry Number 64001-15-6
Food and Chemical Toxicology : FCT, Vol.122 (2018), Supplement 1, pp.S291-S300
info:doi/10.1016/j.fct.2018.08.074
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, Valencene, CAS Registry Number 4630-07-3
Food and Chemical Toxicology : FCT, Vol.118 (2018), Supplement 1, pp.S141-S146
info:doi/10.1016/j.fct.2018.06.047
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, (Z)-4-hepten-1-ol, CAS Registry Number 6191-71-5
Food and Chemical Toxicology : FCT, Vol.115 (2018), Supplement 1, pp.S18-S25
info:doi/10.1016/j.fct.2017.11.035
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton Jr., G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.:
RIFM fragrance ingredient safety assessment, (Z)-Octadec-9-enol, CAS Registry Number 143-28-2
Food and Chemical Toxicology : FCT, Vol.118 (2018), Supplement 1, pp.S156-S161
info:doi/10.1016/j.fct.2018.06.049
Fraunhofer ITEM


Ulmer, Anja; Dietz, Klaus; Werner-Klein, Melanie; Hafner, Hans-Martin; Schulz, Claudia; Renner, Philipp; Weber, Florian; Breuninger, Helmut; Röcken, Martin; Garbe, Claus; Fierlbeck, Gerhard; Klein, Christoph A.:
The sentinel lymph node spread determines quantitatively melanoma seeding to non-sentinel lymph nodes and survival
European journal of cancer : EJC, Vol.91 (2018), pp.1-10
info:doi/10.1016/j.ejca.2017.12.002
Fraunhofer ITEM


Creutzenberg, Otto H.:
Sicherheit im Umgang mit Nanomaterialien
Haas, Karl-Heinz et al.: Angewandte Nanotechnologie. Beispiele aus der Fraunhofer-Allianz Nanotechnologie. Stuttgart: Fraunhofer Verlag, 2018, pp. 304-323
Fraunhofer ITEM


Theobald, Sebastian J.; Khailaie, Sahamoddin; Meyer-Hermann, Michael; Volk, Valery; Olbrich, Henning; Danisch, Simon; Gerasch, Laura; Schneider, Andreas; Sinzger, Christian; Schaudien, Dirk; Lienenklaus, Stefan; Riese, Peggy; Guzman, Carlos A.; Figueiredo, Constanca; Kaisenberg, Constantin von; Spineli, Loukia M.; Glaesener, Stephanie; Meyer-Bahlburg, Almut; Ganser, Arnold; Schmitt, Michael; Mach, Michael; Messerle, Martin; Stripecke, Renata:
Signatures of T and B cell development, functional responses and PD-1 upregulation after HCMV latent infections and reactivations in Nod.Rag.Gamma mice humanized with cord blood CD34(+) cells
Frontiers in Immunology, Vol.9 (2018), Art. 2734, 21 pp.
urn:nbn:de:0011-n-5376844
info:doi/10.3389/fimmu.2018.02734
Volltext
Fraunhofer ITEM


Lorentzen, Anna; Becker, Paul F.; Kosla, Jan; Saini, Massimo; Weidele, Kathrin; Ronchi, Paolo; Klein, Corinna; Wolf, Monika J.; Geist, Felix; Seubert, Bastian; Ringelhan, Marc; Mihic-Probst, Daniela; Esser, Knud; Roblek, Marko; Kuehne, Felix; Bianco, Gaia; O'Connor, Tracy; Müller, Quentin; Schuck, Kathleen; Lange, Sebastian; Hartmann, Daniel; Spaich, Saskia; Gross, Olaf; Utikal, Jochen; Haferkamp, Sebastian; Sprick, Martin R.; Damle-Vartak, Amruta; Hapfelmeier, Alexander; Hüser, Norbert; Protzer, Ulrike; Trumpp, Andreas; Saur, Dieter; Vartak, Nachiket; Klein, Christoph A.; Polzer, Bernhard; Borsig, Lubor; Heikenwalder, Mathias:
Single cell polarity in liquid phase facilitates tumour metastasis
Nature Communications, Vol.9 (2018), Art. 887, 20 pp.
urn:nbn:de:0011-n-4972372
info:doi/10.1038/s41467-018-03139-6
Volltext
Fraunhofer ITEM


Blümlein, Katharina; Elend, Manfred; Meijster, Tim; Margary, Alison; Tibaldi, Rosalie; Hahn, Stefan; Hesse, Susanne:
Solvent transfer - efficiency of risk management measures
Annals of work exposures and health, Vol.62 (2018), No.1, pp.112-123
urn:nbn:de:0011-n-4969873
info:doi/10.1093/annweh/wxx090
Volltext
Fraunhofer ITEM


Takahashi, Kentaro; Pavlidis, Stelios; Ng Kee Kwong, Francois; Hoda, Uruj; Rossios, Christos; Sun, Kai; Loza, Matthew; Baribaud, Fred; Chanez, Pascal; Fowler, Steve J.; Horvath, Ildiko; Montuschi, Paolo; Singer, Florian; Musial, Jacek; Dahlén, Barbro; Dahlén, Sven-Erik; Krug, Norbert; Sandström, Thomas; Shaw, Dominick E.; Lutter, René; Bakke, Per; Fleming, Louise J.; Howarth, Peter H.; Caruso, Massimo; Sousa, Ana R.; Corfield, Julie; Auffray, Charles; Meulder, Bertrand de; Lefaudeux, Diane; Djukanovic, Ratko; Sterk, Peter J.; Guo, Yike; Adcock, Ian M.; Chung, Kian Fan:
Sputum proteomics and airway cell transcripts of current and ex-smokers with severe asthma in U-BIOPRED: An exploratory analysis
European Respiratory Journal, Vol.51 (2018), No.5, Art. 1702173, 19 pp.
info:doi/10.1183/13993003.02173-2017
Fraunhofer ITEM


Hoffmann, Martin; Galle, Jörg:
Stochastic system identification without an a priori chosen kinetic model - exploring feasible cell regulation with piecewise linear functions
npj Systems biology and applications, Vol.4 (2018), Art. 15, 11 pp.
urn:nbn:de:0011-n-4976198
info:doi/10.1038/s41540-018-0049-0
Volltext
Fraunhofer ITEM


Chen, Shukun; El-Heliebi, Amin; Schmid, Julia; Kashofer, Karl; Czyz, Zbigniew T.; Polzer, Bernhard Michael; Pantel, Klaus; Kroneis, Thomas; Sedlmayr, Peter:
Target cell pre-enrichment and whole genome amplification for single cell downstream characterization
Journal of visualized experiments : JoVE. Online resource, Vol.135 (2018), Art. e56394, 10 pp.
urn:nbn:de:0011-n-5099255
info:doi/10.3791/56394
Volltext
Fraunhofer ITEM


Yu, Yong; Schleich, Kolja; Yue, Bin; Ji, Sujuan; Lohneis, Philipp; Kemper, Kristel; Silvis, Mark S.; Qutob, Nouar; Rooijen, Ellen van; Werner-Klein, Melanie; Li, Lianjie; Dhawan, Dhriti; Meierjohann, Svenja; Reimann, Maurice; Elkahloun, Abdel; Treitschke, Steffi; Dörken, Bernd; Speck, Christian; Mallette, Frederick A.; Zon, Leonard I.; Holmen, Sheri L.; Peeper, Daniel S.; Samuels, Yardena; Schmitt, Clemens A.; Lee, Soyoung:
Targeting the senescence-overriding cooperative activity of structurally unrelated H3K9 demethylases in melanoma
Cancer cell, Vol.33 (2018), No.2, pp.322-336.e8
info:doi/10.1016/j.ccell.2018.01.002
Fraunhofer ITEM


Zmora, Pawel; Hoffmann, Markus; Kollmus, Heike; Moldenhauer, Anna-Sophie; Danov, Olga; Braun, Armin; Winkler, Michael; Schughart, Klaus; Pöhlmann, Stefan:
TMPRSS11A activates the influenza A virus hemagglutinin and the MERS coronavirus spike protein and is insensitive against blockade by HAI-1
The Journal of biological chemistry, Vol.293 (2018), No.36, pp.13863-13873
info:doi/10.1074/jbc.RA118.001273
Fraunhofer ITEM


Schofield, James P.R.; Bigler, Jeanette; Boedigheimer, Michael; Affleck, Karen; Taylor, Adam; Pavlidis, Stelios; Riley, John H.; Strazzeri, Fabio; Roberts, Graham; Brandsma, Joost; Bansal, Aruna T.; Nicholas, Ben; Xian, Yang; Rowe, Anthony; Corfield, Julie; Wilson, Susan J.; Ward, Jonathan A.; Lutter, René; Fleming, Louise; Shaw, Dominick E.; Per, Bakke; Caruso, Massimo; Dahlén, Sven-Erik; Fowler, Stephen J.; Hashimoto, Simone; Horváth, Ildikó; Howarth, Peter; Krug, Norbert; Montuschi, Paolo; Sanak, Marek; Sandstrom, Thomas; Singer, Florian; Sun, Kai; Pandis, Ioannis; Auffray, Charles; Meulder, Bertrand de; Lefaudeux, Diane; Knowles, Richard; Fitch, Neil; Sousa, Ana R.; Adcock, Ian M.; Chung, Kian Fan; Sterk, Peter J.; Skipp, Paul; Djukanović, Ratko:
Topological data analysis (TDA) of U-BIOPRED paediatric peripheral blood gene expression identified asthma phenotypes characterised by alternative splicing of glucocorticoid receptor (GR) mRNA. (European Respiratory Society (ERS International Congress) <2018, Paris>)
European Respiratory Journal, Vol.52 (2018), Supplement 62, Abstract PA5435
info:doi/10.1183/13993003.congress-2018.PA5435
Fraunhofer ITEM


Grinberg, Marianna; Stöber, Regina M.; Albrecht, Wiebke; Edlund, Karolina; Schug, Markus; Godoy, Patricio; Cadenas, Cristina; Marchan, Rosemarie; Lampen, Alfonso; Braeuning, Albert; Buhrke, Thorsten; Leist, Marcel; Oberemm, Axel; Hellwig, Birte; Kamp, Hennicke; Gardner, Iain; Escher, Sylvia E.; Taboureau, Olivier; Aguayo-Orozco, Alejandro; Sachinidis, Agapios; Ellinger-Ziegelbauer, Heidrun; Rahnenfuhrer, Jörg; Hengstler, Jan G.:
Toxicogenomics directory of rat hepatotoxicants in vivo and in cultivated hepatocytes
Archives of toxicology, Vol.92 (2018), No.12, pp.3517-3533
info:doi/10.1007/s00204-018-2352-3
Fraunhofer ITEM


Obernolte, Helena; Braubach, Peter; Jonigk, Danny; Beinke, Soren; Belyaev, Nikolai N.; Lennon, Mark; Warnecke, Gregor; Fieguth, Hans-Gerd; Hessel, Edith M.; Braun, Armin; Sewald, Katherina; Wronski, Sabine; Twisterling, Serrao E.:
Transcriptomic analyses reveal anti-viral responses of epithelial cells and multiple immune cell types in HRV infected human lung tissue. (European Academy of Allergology and Clinical Immunology (EAACI Congress) <2018, Munich>)
Allergy. European journal of allergy and clinical immunology, Vol.73 (2018), Supplement 105, pp.240
Fraunhofer ITEM


Plappert, Linda; Jäger, Benedikt; Kraus, Kim Jessica; Wollin, Lutz; Prasse, Antje:
Treatment with nintedanib attenuates fibrosis in a new humanized mouse model for idiopathic pulmonary fibrosis. (Deutsche Gesellschaft für Pneumologie und Beatmungsmedizin, Sektionen Zellbiologie und Infektiologie (Herbsttagung) <2017, Gießen>)
Pneumologie, Vol.72 (2018), No.3, pp.229
info:doi/10.1055/s-0037-1615324
Fraunhofer ITEM


Meulder, Bertrand de; Yen, Romain Tching Chi; Li, Chuan-Xing; Wheelock, Asa; Chung, Kian Fan; Adcock, Ian M.; Djukanović, Ratko; Wagers, Scott; Riley, John; Erpenbeck, Veit J.; Bakke, Per; Caruso, Massimo; Chanez, Pascal; Dahlén, Sven-Erik; Fowler, Stephen J.; Horváth, Ildikó; Krug, Norbert; Montuschi, Paolo; Sanak, Marek; Sandström, Thomas; Shaw, Dominic; Singer, Florian; Pandis, Ioannis; Bansal, Aruna T.; Sterk, Peter J.; Baribaud, Frédéric; Auffray, Charles:
U-BIOPRED accessible handprint: Combining omics platforms to identify stable asthma subphenotypes. (European Respiratory Society (ERS International Congress) <2018, Paris>)
European Respiratory Journal, Vol.52 (2018), Supplement 62, Abstract OA3578
info:doi/10.1183/13993003.congress-2018.OA3578
Fraunhofer ITEM


Wiedemeier, Petra; Horstmann, Wolfram (1. Gutachter); Weigt, Henning (2. Gutachter) :
Der Umgang mit Forschungsdaten, im Kontext der Open Research Anforderungen, an außeruniversitären Forschungseinrichtungen – am Beispiel des Fraunhofer-Instituts für Toxikologie und Experimentelle Medizin (ITEM) als Teil der Fraunhofer-Gesellschaft
Berlin, Univ., Master Thesis, 2018
Fraunhofer ITEM


Gripp, Tatjana; Noll, Thomas (1. Gutachter); Ziemann, Christina (2. Gutachter) :
Untersuchungen zum zytotoxischen, gentoxischen und pro-inflammatorischen Potential von Graphen-Nanoplättchen in Rattenalveolarmakrophagen
Bielefeld, Univ., Master Thesis, 2018
Fraunhofer ITEM


Water, Bob van de; Kamp, Hennicke; Escher, Sylvia E.; Kroese, Dinant:
Use of new approach methods to support chemical read-across: The EU-ToxRisk experience. (European Societies of Toxicology (EUROTOX Congress) <54, 2018, Brussels>)
Toxicology letters, Vol.295 (2018), Supplement 1, pp.S10, Abstract CEC5-40
info:doi/10.1016/j.toxlet.2018.06.038
Fraunhofer ITEM


Carstensen, Saskia; Holz, Olaf; Müller, Meike; Hohlfeld, Jens M.:
Validation of cell analysis by chipcytometry in induced sputum cells. (American Thoracic Society (ATS International Conference) <2018, San Diego/Calif.>)
American Journal of Respiratory and Critical Care Medicine, Vol.197 (2018), Abastract A4768
Fraunhofer ITEM