Monfort, E.; López-Lilao, A.; Escrig, A.; Ibanez, M.J.; Bonvicini, G.; Creutzenberg, O.; Ziemann, C.:
Additives for reducing the toxicity of respirable crystalline silica. SILIFE project. (International Conference Energy, Environment and Material Systems (EEMS) <2017, Polanica-Zdrój>)
Wzorek, M.: International Conference Energy, Environment and Material Systems 2017: 13-15 September 2017, Polanica-Zdrój. Les Ulis: EDP Sciences, 2017. (E3S Web of Conferences 19), Art. 02030, 5 pp.
info:doi/10.1051/e3sconf/20171902030
Fraunhofer ITEM


Sullivan, K.M.; Enoch, S.J.; Ezendam, J.; Sewald, K.; Roggen, E.L.; Cochrane, S.:
An Adverse Outcome Pathway for Sensitization of the Respiratory Tract by Low-Molecular-Weight Chemicals: Building Evidence to Support the Utility of In Vitro and In Silico Methods in a Regulatory Context
Applied in vitro toxicology, Vol.3 (2017), 3, pp.213-226
info:doi/10.1089/aivt.2017.0010
Fraunhofer ITEM


Leist, M.; Ghallab, A.; Graepel, R.; Marchan, R.; Hassan, R.; Bennekou, S.H.; Limonciel, A.; Vinken, M.; Schildknecht, S.; Waldmann, T.; Danen, E.; Ravenzwaay, B. van; Kamp, H.; Gardner, I.; Godoy, P.; Bois, F.Y.; Braeuning, A.; Reif, R.; Oesch, F.; Drasdo, D.; Höhme, S.; Schwarz, M.; Hartung, T.; Braunbeck, T.; Beltman, J.; Vrieling, H.; Sanz, F.; Forsby, A.; Gadaleta, D.; Fisher, C.; Kelm, J.; Fluri, D.; Ecker, G.; Zdrazil, B.; Terron, A.; Jennings, P.; Burg, B. van der; Dooley, S.; Meijer, A.H.; Willighagen, E.; Martens, M.; Evelo, C.; Mombelli, E.; Taboureau, O.; Mantovani, A.; Hardy, B.; Koch, B.; Escher, S.; Thriel, C. van; Cadenas, C.; Kroese, D.; Water, B. van de; Hengstler, J.G.:
Adverse outcome pathways: Opportunities, limitations and open questions
Archives of toxicology, Vol.91 (2017), No.11, pp.3477-3505
info:doi/10.1007/s00204-017-2045-3
Fraunhofer ITEM


Pfaar, O.; Calderon, M.A.; Andrews, C.P.; Angjeli, E.; Bergmann, K.C.; Bonlokke, J.H.; Blay, F. de; Devillier, P.; Ellis, A.K.; Wijk, R.G. van; Hohlfeld, J.M.; Horak, F.; Jacobs, R.L.; Jacobsen, L.; Jutel, M.; Kaul, S.; Larche, M.; Larenas-Linnemann, D.; Mosges, R.; Nolte, H.; Patel, P.; Peoples, L.; Rabin, R.L.; Rather, C.; Salapatek, A.M.; Sigsgaard, T.; Thaarup, S.; Yang, J.; Zieglmayer, P.; Zuberbier, T.; Demoly, P.:
Allergen exposure chambers: harmonizing current concepts and projecting the needs for the future - an EAACI Position Paper
Allergy. European journal of allergy and clinical immunology, Vol.72 (2017), No.7, pp.1035-1042
info:doi/10.1111/all.13133
Fraunhofer ITEM


Obernolte, H.; Braubach, P.; Jonigk, D.; Kruger, M.; Warnecke, G.; Pfennig, O.; Fieguth, H.-G.; Braun, A.; Sewald, K.; Wronski, S.:
Anti-viral and inflammatory host response to rhinovirus is induced in vital ex vivo human lung tissue and reduced by anti-viral treatments. (American Thoracic Society (ATS International Conference) <2017, Washington/DC>)
American Journal of Respiratory and Critical Care Medicine, Vol.195 (2017), Art. A4040
Fraunhofer ITEM


Bundschuh, Mirco; Hahn, Torsten; Gessner, Mark O.; Schulz, Ralf:
Antibiotic mixture effects on growth of the leaf-shredding stream detritivore Gammarus fossarum
Ecotoxicology, Vol.26 (2017), No.4, pp.547-554
urn:nbn:de:0011-n-4814694
info:doi/10.1007/s10646-017-1787-2
Volltext
Fraunhofer ITEM


Baydoun, Luma; Ziehr, Holger:
Aseptische Abfüllung biopharmazeutischer Prüfarzneimittel
Die Pharmazeutische Industrie, Vol.79 (2017), No.1, pp.126-132
Fraunhofer ITEM


Neuhaus, V.; Schaudien, D.; Golovina, T.; Temann, U.-A.; Thompson, C.; Lippmann, T.; Bersch, C.; Pfennig, O.; Jonigk, D.; Braubach, P.; Fieguth, H.-G.; Warnecke, G.; Yusibov, V.; Sewald, K.; Braun, A.:
Assessment of long-term cultivated human precision-cut lung slices as an ex vivo system for evaluation of chronic cytotoxicity and functionality
Journal of occupational medicine and toxicology. Online journal, Vol.12 (2017), No.1, Art. 13, 8 pp.
info:doi/10.1186/s12995-017-0158-5
Fraunhofer ITEM


Lamb, J.; Galea, K.S.; Miller, B.G.; Hesse, S.; Tongeren, M. van:
Between-User Reliability of Tier 1 Exposure Assessment Tools Used Under REACH
Annals of work exposures and health, Vol.61 (2017), 8, pp.939-953
info:doi/10.1093/annweh/wxx074
Fraunhofer ITEM


Laux, Peter; Riebeling, Christian; Booth, Andy M.; Brain, Joseph D.; Brunner, Josephine; Cerrillo, Cristina; Creutzenberg, Otto H.; Estrela-Lopis, Irina; Gebel, Thomas; Johanson, Gunnar; Jungnickel, Harald; Kock, Heiko; Tentschert, Jutta; Tlili, Ahmed; Schäffer, Andreas; Sips, Adriënne J.A.M.; Yokel, Robert A.; Luch, Andreas:
Biokinetics of nanomaterials. The role of biopersistence
NanoImpact, Vol.6 (2017), pp.69-80
urn:nbn:de:0011-n-4878809
info:doi/10.1016/j.impact.2017.03.003
Volltext
Fraunhofer ITEM


Lindner, Karina; Ströbele, Michael; Schlick, Sandra; Webering, Sina; Jenckel, André; Kopf, Johannes; Danov, Olga; Sewald, Katherina; Buj, Christian; Creutzenberg, Otto; Tillmann, Thomas; Pohlmann, Gerhard; Ernst, Heinrich; Ziemann, Christina; Hüttmann, Gereon; Heine, Holger; Bockhorn, Henning; Hansen, Tanja; König, Peter:
Biological effects of carbon black nanoparticles are changed by surface coating with polycyclic aromatic hydrocarbons
Particle and Fibre Toxicology, Vol.14 (2017), Art. 8, 17 pp.
urn:nbn:de:0011-n-4417094
info:doi/10.1186/s12989-017-0189-1
Volltext
Fraunhofer ITEM


Krug, N.; Hohlfeld, J.M.; Buhl, R.; Renz, J.; Garn, H.; Renz, H.:
Blood eosinophils predict therapeutic effects of a GATA3-specific DNAzyme in asthma patients: Letter to the Editor
The journal of allergy and clinical immunology : JACI, Vol.140 (2017), No.2, pp.625-628
info:doi/10.1016/j.jaci.2017.02.024
Fraunhofer ITEM


Chen, Shukun; El-Heliebi, Amin; Tauber, Gerlinde; Langsenlehner, Tanja; Pötscher, Michaela; Kashofer, Karl; Czyz, Zbigniew T.; Polzer, Bernhard; Riethdorf, Sabine; Kuske, Andra; Leitinger, Gerd; Pantel, Klaus; Kroneis, Thomas; Sedlmayr, Peter:
Catch and release: Rare cell analysis from a functionalised medical wire
Scientific Reports, Vol.7 (2017), Art. 43424, 8 pp.
urn:nbn:de:0011-n-4528330
info:doi/10.1038/srep43424
Volltext
Fraunhofer ITEM


Schäfer, Claudia; Göder, Anja; Beyer, Mandy; Kiweler, Nicole; Mahendrarajah, Nisintha; Rauch, Anke; Nikolova, Teodora; Stojanovic, Natasa; Wieczorek, Martin; Reich, Thomas R.; Tomicic, Maja T.; Linnebacher, Michael; Sonnemann, Jürgen; Dietrich, Sascha; Sellmer, Andreas; Mahboobi, Siavosh; Heinzel, Thorsten; Schneider, Günter; Krämer, Oliver H.:
Class I histone deacetylases regulate p53/NF-kappaB crosstalk in cancer cells
Cellular signalling, Vol.29 (2017), pp.218-225
info:doi/10.1016/j.cellsig.2016.11.002
Fraunhofer ITEM


Hess, R.; Wujak, L.; Hesse, C.; Sewald, K.; Jonigk, D.; Warnecke, G.; Fieguth, H.-G.; Maat, S. de; Maas, C.; Bonella, F.; Preissner, K.T.; Weiss, B.; Schaefer, L.; Kuebler, W.M.; Markart, P.; Wygrecka, M.:
Coagulation factor XII regulates inflammatory responses in human lungs
Thrombosis and haemostasis, Vol.117 (2017), No.10, pp.1896-1909
info:doi/10.1160/TH16-12-0904
Fraunhofer ITEM


Walter, D.; Schaudien, D.; Sewald, K.; Braun, A.; Hoymann, H.G.:
Comparison Of Bleomycin Models Of Pulmonary Fibrosis In Rats And Mice. (American Thoracic Society (ATS International Conference) <2017, Washington/DC>)
American Journal of Respiratory and Critical Care Medicine, Vol.195 (2017), Abstract Issue American Thoracic Society 2017 International Conference, Abstract A7260
Fraunhofer ITEM


Kotsampasakou, Eleni; Escher, Sylvia E.; Ecker, Gerhard F.:
Curated human hyperbilirubinemia data and the respective OATP1B1 and 1B3 inhibition predictions
Data in Brief, Vol.11 (2017), pp.204-207
urn:nbn:de:0011-n-4814673
info:doi/10.1016/j.dib.2017.02.009
Volltext
Fraunhofer ITEM


Kerrin, A.; Fitch, P.; Errington, C.; Kerr, D.; Waxman, L.; Riding, K.; McCormack, J.; Mehendele, F.; McSorley, H.; MacKenzie, K.; Wronski, S.; Braun, A.; Levin, R.; Theilen, U.; Schwarze, J.:
Differential lower airway dendritic cell patterns may reveal distinct endotypes of RSV bronchiolitis
Thorax, Vol.72 (2017), No.7, pp.620-627
info:doi/10.1136/thoraxjnl-2015-207358
Fraunhofer ITEM


Schumacher, S.; Bartenhagen, C.; Hoffmann, M.; Will, D.; Fischer, J.C.; Baldus, S.E.; Vay, C.; Fluegen, G.; Dizdar, L.; Vallböhmer, D.; Klein, C.A.; Knoefel, W.T.; Stoecklein, N.H.; Möhlendick, B.:
Disseminated tumour cells with highly aberrant genomes are linked to poor prognosis in operable oesophageal adenocarcinoma
The British journal of cancer, Vol.117 (2017), No.5, pp.725-733
info:doi/10.1038/bjc.2017.233
Fraunhofer ITEM


Pfaar, O.; Hohlfeld, J.M.; Al-Kadah, B.; Hauswald, B.; Homey, B.; Hunzelmann, N.; Schliemann, S.; Velling, P.; Worm, M.; Klimek, L.:
Dose-response relationship of a new Timothy grass pollen allergoid in comparison with a 6-grass pollen allergoid
Clinical & experimental allergy, Vol.47 (2017), No.11, pp.1445-1455
info:doi/10.1111/cea.12977
Fraunhofer ITEM


Deus, D.; Kehrenberg, C.; Schaudien, Dirk; Klein, G.; Krischek, Carsten:
Effect of a nano-silver coating on the quality of fresh turkey meat during storage after modified atmosphere or vacuum packaging
Poultry science, Vol.96 (2017), No.2, pp.449-457
info:doi/10.3382/ps/pew308
Fraunhofer ITEM


Schwotzer, D.; Ernst, H.; Schaudien, D.; Kock, H.; Pohlmann, G.; Dasenbrock, C.; Creutzenberg, O.:
Effects from a 90-day inhalation toxicity study with cerium oxide and barium sulfate nanoparticles in rats
Particle and Fibre Toxicology, Vol.14 (2017), Art. 23, 20 pp.
info:doi/10.1186/s12989-017-0204-6
Fraunhofer ITEM


Behr, Jürgen; Günther, Andreas; Kreuter, Michael; Koschel, Dirk; Prasse, Antje; Pfeifer, Michael; Costabel, Ulrich:
Erfahrungen und unterstützende Hinweise zur Anwendung von Nintedanib bei Patienten mit idiopathischer Lungenfibrose
Pneumologie, Vol.71 (2017), No.9, pp.567-579
info:doi/10.1055/s-0043-109856
Fraunhofer ITEM


Havlik, D.; Brandt, U.; Bohle, K.; Fleissner, A.:
Establishment of Neurospora crassa as a host for heterologous protein production using a human antibody fragment as a model product
Microbial cell factories. Online journal, Vol.16 (2017), Art. 128, 15 pp.
info:doi/10.1186/s12934-017-0734-5
Fraunhofer ITEM


Horvath, I.; Barnes, P.J.; Loukides, S.; Sterk, P.J.; Hogman, M.; Olin, A.C.; Amann, A.; Antus, B.; Baraldi, E.; Bikov, A.; Boots, A.W.; Bos, L.D.; Brinkman, P.; Bucca, C.; Carpagnano, G.E.; Corradi, M.; Cristescu, S.; Jongste, J.C. de; Dinh-Xuan, A.T.; Dompeling, E.; Fens, N.; Fowler, S.; Hohlfeld, J.M.; Holz, O.; Jobsis, Q.; Kant, K.V. van de; Knobel, H.H.; Kostikas, K.; Lehtimaki, L.; Lundberg, J.; Montuschi, P.; Muylem, A. van; Pennazza, G.; Reinhold, P.; Ricciardolo, F.L.M.; Rosias, P.; Santonico, M.; Schee, M.P. van der; Schooten, F.J. van; Spanevello, A.; Tonia, T.; Vink, T.J.:
A European Respiratory Society technical standard: exhaled biomarkers in lung disease
European Respiratory Journal, Vol.49 (2017), No.4, Art. 1600965, 26 pp.
info:doi/10.1183/13993003.00965-2016
Fraunhofer ITEM


Granitzny, Anne; Knebel, Jan; Müller, Meike; Braun, Armin; Steinberg, Pablo; Dasenbrock, Clemens; Hansen, Tanja:
Evaluation of a human in vitro hepatocyte-NPC co-culture model for the prediction of idiosyncratic drug-induced liver injury: A pilot study
Toxicology reports, Vol.4 (2017), pp.89-103
urn:nbn:de:0011-n-4814685
info:doi/10.1016/j.toxrep.2017.02.001
Volltext
Fraunhofer ITEM


Temann, A.; Golovina, T.; Neuhaus, V.; Thompson, C.; Chichester, J.A.; Braun, A.; Yusibov, V.:
Evaluation of inflammatory and immune responses in long-term cultured human precision-cut lung slices. (World Congress on Vaccines, Immunisation and Immunotherapy (WCVII) <10, 2016, Bern>)
Human vaccines and immunotherapeutics, Vol.13 (2017), No.2, pp.351-358
info:doi/10.1080/21645515.2017.1264794
Fraunhofer ITEM


Tischer, M.; Lamb, J.; Hesse, S.; Tongeren, M. van:
Evaluation of Tier One Exposure Assessment Models (ETEAM): Project Overview and Methods
Annals of work exposures and health, Vol.61 (2017), No.8, pp.911-920
info:doi/10.1093/annweh/wxx066
Fraunhofer ITEM


Boge, L.; Muller, M.; Jonigk, D.; Braubach, P.; Fieguth, H.G.; Warnecke, G.; Kruger, M.; Braun, A.; Sewald, K.; Wronski, S.:
Ex-Vivo Infection Of Fresh Human Lung Tissue With Pseudomonas AerugINOSa. (American Thoracic Society (ATS International Conference) <2017, Washington/DC>)
American Journal of Respiratory and Critical Care Medicine, Vol.195 (2017), Abstract Issue American Thoracic Society 2017 International Conference, Abstract A1271
Fraunhofer ITEM


Nastevska, Cathrin (Red.); Schlemminger, Karin (Übers.) ; Fraunhofer-Institut für Toxikologie und Experimentelle Medizin -ITEM-, Hannover:
Fraunhofer-Institut für Toxikologie und Experimentelle Medizin. Leistungen und Ergebnisse. Jahresbericht 2016/2017
Hannover: Fraunhofer ITEM, 2017
urn:nbn:de:0011-n-4591636
Volltext
Fraunhofer ITEM


Wujak, L.; Hesse, C.; Sewald, K.; Jonigk, D.; Braubach, P.; Warnecke, G.; Fieguth, H.-G.; Braun, A.; Lochnit, G.; Markart, P.; Schaefer, L.; Wygrecka, M.:
FXII promotes proteolytic processing of the LRP1 ectodomain
Biochimica et biophysica acta. General subjects, Vol.1861 (2017), No.8, pp.2088-2098
info:doi/10.1016/j.bbagen.2017.05.023
Fraunhofer ITEM


Tsikas, Dimitrios; Kayacelebi, Arslan Arinc; Hanff, Erik; Mitschke, Anja; Beckmann, Bibiana; Tillmann, Hanns-Christian; Gutzki, Frank-Mathias; Müller, Meike; Bernasconi, Corrado:
GC-MS and GC-MS/MS measurement of ibuprofen in 10-μL aliquots of human plasma and mice serum using alpha-methylo-H-2(3)]ibuprofen after ethyl acetate extraction and pentafluorobenzyl bromide derivatization: Discovery of a collision energy-dependent H/D isotope effect and pharmacokinetic application to inhaled ibuprofen-arginine in mice
Journal of chromatography. B, Vol.1043 (2017), pp.158-166
info:doi/10.1016/j.jchromb.2016.06.014
Fraunhofer ITEM


Kreuter, M.; Swigris, J.; Pittrow, D.; Geier, S.; Klotsche, J.; Prasse, A.; Wirtz, H.; Koschel, D.; Andreas, S.; Claussen, M.; Grohe, C.; Wilkens, H.; Hagmeyer, L.; Skowasch, D.; Meyer, J.F.; Kirschner, J.; Glaser, S.; Herth, F.J.F.; Welte, T.; Neurohr, C.; Schwaiblmair, M.; Held, M.; Bahmer, T.; Frankenberger, M.; Behr, J.:
Health related quality of life in patients with idiopathic pulmonary fibrosis in clinical practice: insights-IPF registry
Respiratory research. Online journal, Vol.18 (2017), Art. 139, 10 pp.
info:doi/10.1186/s12931-017-0621-y
Fraunhofer ITEM


Holzschuh, M.-A.; Czyz, Z.; Hauke, S.; Inwald, E.C.; Polzer, B.; Brockhoff, G.:
HER2 FISH results in breast cancers with increased CEN17 signals using alternative chromosome 17 probes - reclassifying cases in the equivocal category
Histopathology, Vol.71 (2017), No.4, pp.610-625
info:doi/10.1111/his.13253
Fraunhofer ITEM


Meinlschmidt, Pia; Brode, Viktoria; Sevenich, R.; Ueberham, E.; Schweiggert-Weisz, U.; Lehmann, J.; Rauh, C.; Knorr, D.; Eisner, P.:
High pressure processing assisted enzymatic hydrolysis - An innovative approach for the reduction of soy immunoreactivity
Innovative food science & emerging technologies, Vol.40 (2017), pp.58-67
info:doi/10.1016/j.ifset.2016.06.022
Fraunhofer ITEM
Fraunhofer IVV 3557
Fraunhofer IZI


Mülleder, M.; Bluemlein, K.; Ralser, M.:
A high-throughput method for the quantitative determination of free amino acids in saccharomyces cerevisiae by hydrophilic interaction chromatography-tandem mass spectrometry
Cold Spring Harbor protocols, (2017), No.9, pp.729-734
info:doi/10.1101/pdb.prot089094
Fraunhofer ITEM


Sundarasetty, Balasai; Volk, Valery; Theobald, Sebastian J.; Rittinghausen, Susanne; Schaudien, Dirk; Neuhaus, Vanessa; Figueiredo, Constanca; Schneider, Andreas; Gerasch, Laura; Mucci, Adele; Moritz, Thomas; Kaisenberg, Constantin von; Spineli, Loukia M.; Sewald, Katherina; Braun, Armin; Weigt, Henning; Ganser, Arnold; Stripecke, Renata:
Human effector memory T helper cells engage with mouse macrophages and cause Graft-versus-Host-like pathology in skin of humanized mice used in a nonclinical immunization study
The American journal of pathology, Vol.187 (2017), No.6, pp.1380-1398
info:doi/10.1016/j.ajpath.2017.02.015
Fraunhofer ITEM


Bower, D.; Cross, K.P.; Escher, Sylvia E.; Myatt, Glenn J.; Quigley, D.P.:
In silico toxicology: An overview of toxicity databases, prediction methodologies, and expert review: chapter 9
Johnson, D.E.: Computational systems pharmacology and toxicology. Cambridge: RSC, 2017. (Issues in toxicology 31), pp. 209-242
info:doi/10.1039/9781782623731-00209
Fraunhofer ITEM


Granitzny, A.:
In vitro/ex vivo liver models for the prediction of idiosyncratic drug-induced liver injury
Hannover, Tierärztliche Hochschule, Diss., 2017
urn:nbn:de:gbv:95-110521
Fraunhofer ITEM


Engel, M.; Endesfelder, D.; Schloter-Hai, B.; Kublik, S.; Granitsiotis, M.S.; Boschetto, P.; Stendardo, M.; Barta, I.; Dome, B.; Deleuze, J.F.; Boland, A.; Müller-Quernheim, J.; Prasse, A.; Welte, T.; Hohlfeld, J.; Subramanian, D.; Parr, D.; Gut, I.G.; Greulich, T.; Koczulla, A.R.; Nowinski, A.; Gorecka, D.; Singh, D.; Gupta, S.; Brightling, CE.; Hoffmann, H.; Frankenberger, M.; Hofer, TP.; Burggraf, D.; Heiss-Neumann, M.; Ziegler-Heitbrock, L.; Schloter, M.; Castell, W. zu:
Influence of lung CT changes in chronic obstructive pulmonary disease (COPD) on the human lung microbiome
PLoS one. Online journal, Vol.12 (2017), No.7, Art. e0180859, 22 pp.
info:doi/10.1371/journal.pone.0180859
Fraunhofer ITEM


Kernberger-Fischer, I.; Kehrenberg, C.; Klein, G.; Schaudien, D.; Krischek, C.:
Influence of modified atmosphere and vacuum packaging with and without nanosilver-coated films on different quality parameters of pork
Journal of Food Science and Technology, Vol.54 (2017), No.10, pp.3251-3259
info:doi/10.1007/s13197-017-2768-4
Fraunhofer ITEM


Tank, J.; Heusser, K.; Holz, O.; May, M.; Brinkmann, J.; Diedrich, A.; Framke, T.; Koch, A.; Grosshennig, A.; Sweep, F.C.G.J.; Koch, W.; Krug, N.; Jordan, J.; Hohlfeld, J.:
Influences of Experimental Air Pollution on Human Sympathetic Nerve Traffic and Norepinephrine Metabolism: A Double Blind, Randomized, Twofold Crossover Study. (American Society for Pharmacology and Experimental Therapeutics (ASPET Annual Meeting) <2017, Chicago/Ill.>)
FASEB journal, Vol.31 (2017), No.1, Supplement
Fraunhofer ITEM


Konzok, S.; Dehmel, S.; Braubach, P.; Kruger, M.; Jonigk, D.; Warnecke, G.; Pfennig, O.; Fieguth, H.G.; Braun, A.; Sewald, K.:
Interactions Of Cancer Cell Line Mda-Mb-231 With Their Native Tumor Microenvironment And Anti-Cancer Effects Of Bevacizumab And Cisplatin On Cancer Cell Invaded Human Living Lung Tissue. (American Thoracic Society (ATS International Conference) <2017, Washington/DC>)
American Journal of Respiratory and Critical Care Medicine, Vol.195 (2017), Abstract Issue American Thoracic Society 2017 International Conference, Abstract A2362
Fraunhofer ITEM


Veres, Tibor Z.; Kopcsányi, Támas; Tirri, Marko; Braun, Armin; Miyasaka, Masayuki; Germain, Ronald N.; Jalkanen, Sirpa; Salmi, Marko:
Intubation-free in vivo imaging of the tracheal mucosa using two-photon microscopy
Scientific Reports, Vol.7 (2017), Art. 694, 9 pp.
urn:nbn:de:0011-n-4524532
info:doi/10.1038/s41598-017-00769-6
Volltext
Fraunhofer ITEM


Schwarz, K.; Fischer, M.; Dasenbrock, C.; Koch, W.; Walter, D.:
The isolated perfused lung (IPL) model for toxicity and efficacy testing and absorption studies of inhalable substances. (International Society for Aerosols in Medicine (ISAM International Congress) <21, 2017, Santa Fe/NM>)
Journal of aerosol medicine and pulmonary drug delivery, Vol.30 (2017), No.3, pp.A11
Fraunhofer ITEM


Sanz, F.; Pognan, F.; Steger-Hartmann, T.; Díaz, C.; Cases, M.; Pastor, M.; Marc, P.; Wichard, J.; Briggs, K.; Watson, D.K.; Kleinöder, T.; Yang, C.; Amberg, A.; Beaumont, M.; Brookes, A.J.; Brunak, S.; Cronin, M.T.D.; Ecker, G.F.; Escher, S.; Greene, N.; Guzmán, A.; Hersey, A.; Jacques, P.; Lammens, L.; Mestres, J.; Muster, W.; Northeved, H.; Pinches, M.; Saiz, J.; Sajot, N.; Valencia, A.; Lei,, J. van der; Vermeulen, N.P.E.; Vock, E.; Wolber, G.; Zamora, I.:
Legacy data sharing to improve drug safety assessment: The eTOX project
Nature reviews. Drug discovery, Vol.16 (2017), pp.811-812
info:doi/10.1038/nrd.2017.177
Fraunhofer ITEM


Kotsampasakou, Eleni; Escher, Sylvia E.; Ecker, Gerhard F.:
Linking organic anion transporting polypeptide 1B1 and 1B3 (OATP1B1 and OATP1B3) interaction profiles to hepatotoxicity - The hyperbilirubinemia use case
European journal of pharmaceutical sciences : EUFEPS, Vol.100 (2017), pp.9-16
info:doi/10.1016/j.ejps.2017.01.002
Fraunhofer ITEM


Granitzny, Anne; Knebel, Jan; Schaudien, Dirk; Braun, Armin; Steinberg, Pablo; Dasenbrock, Clemens; Hansen, Tanja:
Maintenance of high quality rat precision cut liver slices during culture to study hepatotoxic responses: Acetaminophen as a model compound
Toxicology in vitro, Vol.42 (2017), pp.200-213
urn:nbn:de:0011-n-4524524
info:doi/10.1016/j.tiv.2017.05.001
Volltext
Fraunhofer ITEM


Hosseini, H.:
Molecular mechanism of early metastatic breast cancer dissemination
Regensburg, Univ., Diss., 2017
urn:nbn:de:bvb:355-epub-357344
Fraunhofer ITEM


Weidele, Kathrin; Beneke, Sascha; Bürkle, Alexander:
The NAD+ precursor nicotinic acid improves genomic integrity in human peripheral blood mononuclear cells after X-irradiation
DNA repair, Vol.52 (2017), pp.12-23
info:doi/10.1016/j.dnarep.2017.02.001
Fraunhofer ITEM


Zmora, Pawel; Molau-Blazejewska, Paulina; Bertram, Stephanie; Walendy-Gnirß, Kerstin; Nehlmeier, Inga; Hartleib, Anika; Moldenhauer, Anna-Sophie; Konzok, Sebastian; Dehmel, Susann; Sewald, Katherina; Brinkmann, Constantin; Curths, Christoph; Knauf, Sascha; Gruber, Jens; Mätz-Rensing, Kerstin; Dahlmann, Franziska; Braun, Armin; Pöhlmann, Stefan:
Non-human primate orthologues of TMPRSS2 cleave and activate the influenza virus hemagglutinin
PLoS one. Online journal, Vol.12 (2017), No.5, Art. e0176597, 14 pp.
urn:nbn:de:0011-n-4527428
info:doi/10.1371/journal.pone.0176597
Volltext
Fraunhofer ITEM


Ziemann, Christina; Escrig, Alberto; Bonvicini, Giuliana; Ibañez, Maria Jesus; Monfort, Eliseo; Salomoni, Arturo; Creutzenberg, Otto H.:
Organosilane-based coating of quartz species from the traditional ceramics industry: Evidence of hazard reduction using in vitro and in vivo tests
Annals of work exposures and health, Vol.61 (2017), No.4, pp.468-480
urn:nbn:de:0011-n-4528367
info:doi/10.1093/annweh/wxx014
Volltext
Fraunhofer ITEM


Halter, Roman; Mangelsdorf, Inge:
Partikel‐ und Fasertoxikologie
Greim, H.: Das Toxikologiebuch: Grundlagen, Verfahren, Bewertung. Weinheim: Wiley-VCH, 2017, pp. 713-743
info:doi/10.1002/9783527695447.ch36
Fraunhofer ITEM


Waschki, Benjamin; Watz, Henrik; Holz, Olaf; Magnussen, Helgo; Olejnicka, Beata; Welte, Tobias; Rabe, Klaus F.; Janciauskiene, Sabina:
Plasminogen activator inhibitor-1 is elevated in patients with COPD independent of metabolic and cardiovascular function
International journal of chronic obstructive pulmonary disease, Vol.12 (2017), pp.981-987
urn:nbn:de:0011-n-4525202
info:doi/10.2147/COPD.S128689
Volltext
Fraunhofer ITEM


Li, L.; Yang, D.; Song, Y.; Shi, Y.; Huang, B.; Bitsch, A.; Yan, J.:
The potential acute and chronic toxicity of cyfluthrin on the soil model organism, Eisenia fetida
Ecotoxicology and environmental safety, Vol.144 (2017), pp.456-463
info:doi/10.1016/j.ecoenv.2017.06.064
Fraunhofer ITEM


Wiegandt, F.C.; Koch, E.; Iwatschenko, P.; Dietzel, A.; Pohlmann, G.:
Pre-triggered dry and liquid aerosol release inside the patient interface of preterm neonates. (International Society for Aerosols in Medicine (ISAM International Congress) <21, 2017, Santa Fe/NM>)
Journal of aerosol medicine and pulmonary drug delivery, Vol.30 (2017), No.3, pp.A28
Fraunhofer ITEM


Kraemer, Nadine; Braun, Armin (1. Prüfer); Häußler, Susanne (2. Prüfer); Wronski, Sabine (Betr.); Müller, Laura (Betr.) :
Pseudomonas aeruginosa induziert eine angeborene Immunantwort in frischem Lungengewebe ex vivo
Hannover, Medizinische Hochschule, Master Thesis, 2017
Fraunhofer ITEM


Przybylak, Katarzyna R.; Schultz, Terry W.; Richarz, Andrea-N.; Mellor, Claire L.; Escher, Sylvia E.; Cronin, M.T.D.:
Read-across of 90-day rat oral repeated-dose toxicity: A case study for selected β-olefinic alcohols
Computational Toxicology, Vol.1 (2017), pp.22-32
info:doi/10.1016/j.comtox.2016.11.001
Fraunhofer ITEM


Schultz, Terry W.; Przybylak, Katarzyna R.; Richarz, Andrea-Nicole; Mellor, Claire L.; Escher, Sylvia E.; Bradbury, Steven P.; Cronin, Mark T. D.:
Read-across of 90-day rat oral repeated-dose toxicity: A case study for selected n-alkanols
Computational Toxicology, Vol.2 (2017), pp.12-19
info:doi/10.1016/j.comtox.2017.02.002
Fraunhofer ITEM


Ikari, J.; Nelson, A.J.; Obaid, J.; Giron-Martinez, A.; Ikari, K.; Makino, F.; Iwasawa, S.; Gunji, Y.; Farid, M.; Wang, X.; Basma, H.; Demeo, D.; Feghali-Bostwick, C.; Holz, O.; Rabe, K.; Liu, X.; Rennard, S.I.:
Reduced microRNA-503 expression augments lung fibroblast VEGF production in chronic obstructive pulmonary disease
PLoS one. Online journal, Vol.12 (2017), No.9, Art. e0184039, 20 pp.
info:doi/10.1371/journal.pone.0184039
Fraunhofer ITEM


Hackner, K.; Errhalt, P.; Doll, T.:
Reply to Comment on 'Canine scent detection for the diagnosis of lung cancer in a screening-like situation'
Journal of breath research, Vol.11 (2017), No.3, Art. 038002, 2 pp.
info:doi/10.1088/1752-7163/aa78fd
Fraunhofer ITEM


Schulz, F.:
Respirationstrakt
Greim, H.: Das Toxikologiebuch: Grundlagen, Verfahren, Bewertung. Weinheim: Wiley-VCH, 2017, pp. 275-296
info:doi/10.1002/9783527695447.ch13
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RFIM fragrance ingredient safety assessment, acetaldehyde ethyl phenylethyl acetal, CAS Registry Number 2556-10-7
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S537-S544
info:doi/10.1016/j.fct.2017.09.040
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment 2-heptylcyclopentanone, CAS Registry Number 137-03-1
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S496-S501
info:doi/10.1016/j.fct.2017.09.034
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment 4-(Isopropyl)cyclohexyl propionate, CAS Registry Number 63449-95-6
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S704-S710
info:doi/10.1016/j.fct.2017.10.046
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, .α.-methylcyclohexylmethyl acetate, CAS Registry Number 13487-27-9
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S242-S252
info:doi/10.1016/j.fct.2017.05.064
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, Jochen; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A. D.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, 1-cyclohexylethyl butyrate, CAS Registry Number 63449-88-7
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S160-S168
info:doi/10.1016/j.fct.2017.04.031
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, 1-methyl-3-methoxy-4-isopropylbenzene, CAS Registry Number 1076-56-8
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S462-S470
info:doi/10.1016/j.fct.2017.08.042
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM Fragrance Ingredient Safety Assessment, 2,2,4-trimethyl-4-phenyl-butane-nitrile CAS Registry Number 75490-39-0
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S368-S374
info:doi/10.1016/j.fct.2017.07.037
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, 2,2,5-trimethyl-5-pentylcyclopentanone, CAS Registry Number 65443-14-3
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S662-S669
info:doi/10.1016/j.fct.2017.10.009
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, 2-isopropyl-4-methylanisole, CAS Registry Number 31574-44-4
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S545-S551
info:doi/10.1016/j.fct.2017.09.039
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, 2-methyl-4(2,2,3-trimethyl-3-cyclopentenyl)butanol, CAS Registry Number 72089-08-8
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S309-S317
info:doi/10.1016/j.fct.2017.06.001
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, 2-pentylcyclopentan-1-one, CAS Registry Number 4819-67-4
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S603-S610
info:doi/10.1016/j.fct.2017.10.016
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, 3,12-Tridecadienenitrile CAS Registry Number 134769-33-8
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S529-S536
info:doi/10.1016/j.fct.2017.09.041
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, 3,6-nonadien-1-ol, CAS registry number 76649-25-7
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S696-S703
info:doi/10.1016/j.fct.2017.10.047
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, 3,7-dimethyl-1-octanol, CAS Registry Number 106-21-8
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S412-S420
info:doi/10.1016/j.fct.2017.07.039
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, 3,7-dimethyl-1-octanyl acetate, CAS Registry Number 20780-49-8
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S151-S159
info:doi/10.1016/j.fct.2017.04.032
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, 3,7-dimethyl-2,6-nonadienenitrile, CAS Registry Number 61792-11-8
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S552-S560
info:doi/10.1016/j.fct.2017.09.047
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, 3-hexen-1-ol (isomer unspecified), CAS Registry Number 544-12-7
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S629-S636
info:doi/10.1016/j.fct.2017.10.013
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, 3-methyl-2-pentylcyclopentan-1-one, CAS Registry Number 13074-63-0
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S447-S454
info:doi/10.1016/j.fct.2017.08.035
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, 3-methylbutyl 2-methylpropanoate, CAS Registry Number 2050-01-3
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S169-S178
info:doi/10.1016/j.fct.2017.04.029
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, 3-methylbutyl valerate, CAS Registry Number 2050-09-1
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S279-S289
info:doi/10.1016/j.fct.2017.06.007
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Bhatia, S.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; Kromidas, L.; La Cava, S.; Lalko, J.F.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Politano, V.T.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.; Wall, B.; Wilcox, D.K.:
RIFM fragrance ingredient safety assessment, 4-(3,4-methylenedioxyphenyl)-2-butanone, CAS Registry Number 55418-52-5
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S273-S278
info:doi/10.1016/j.fct.2017.06.008
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, 4-Carvomenthenol, CAS Registry Number 562-74-3
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S403-S411
info:doi/10.1016/j.fct.2017.07.040
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, 4-isopropyl-2-methoxy-1-methylbenzene, CAS Registry Number 6379-73-3
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S479-S485
info:doi/10.1016/j.fct.2017.09.008
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, 5-Acetyl-3-isopropyl-1,1,2,6-tetramethylindane, CAS Registry Number 68140-48-7
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S198-S209
info:doi/10.1016/j.fct.2017.05.015
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Dekant, W.; Fryer, A.D.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Wahler, J.:
RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT, 6-acetyl-1,1,2,4,4,7-hexamethyltetraline, CAS Registry Number 21145-77-7
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S95-S103
info:doi/10.1016/j.fct.2017.03.019
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, α-methylbenzyl alcohol, CAS registry number 98-85-1
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S569-S576
info:doi/10.1016/j.fct.2017.09.045
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, α-Propylphenethyl alcohol, CAS Registry Number 705-73-7
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S585-S593
info:doi/10.1016/j.fct.2017.09.057
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, acetaldehyde, diphenethyl acetal, CAS Registry Number 122-71-4
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S439-S446
info:doi/10.1016/j.fct.2017.08.036
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, acetic acid, C7-9-branched alkyl esters, C8-rich, CAS Registry Number 108419-32-5
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S234-S241
info:doi/10.1016/j.fct.2017.05.066
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, acetic acid, C8-10-branched alkyl esters, C9-rich, CAS Registry Number 108419-33-6
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S358-S367
info:doi/10.1016/j.fct.2017.07.003
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, Alcohols, C11-14-iso-, C13-rich, CAS Registry Number 68526-86-3
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S687-S695
info:doi/10.1016/j.fct.2017.10.048
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, alcohols, C8-10-iso-, C9-rich, CAS Registry Number 68526-84-1
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S521-S528
info:doi/10.1016/j.fct.2017.09.028
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Dekant, W.; Fryer, A.D.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Wahler, J.:
RIFM fragrance ingredient safety assessment, β-Guaiene, CAS Registry Number 88-84-6
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S9-S15
info:doi/10.1016/j.fct.2016.11.017
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, β-methylphenethyl alcohol, CAS Registry Number 1123-85-9
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S594-S602
info:doi/10.1016/j.fct.2017.09.056
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, benzenepropanenitrile, 4-ethyl-.α.,.α.-dimethyl, CAS Registry Number 134123-93-6
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S344-S350
info:doi/10.1016/j.fct.2017.06.026
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, benzenepropanol, a,ß-dimethyl-, CAS Registry Number 56836-93-2
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S471-S478
info:doi/10.1016/j.fct.2017.09.009
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, benzoic acid, 2-[(1-oxopropyl)amino]-, methyl ester, CAS Registry Number 25628-84-6
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S299-S308
info:doi/10.1016/j.fct.2017.06.002
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, butyl anthranilate, CAS Registry Number 7756-96-9
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S222-S233
info:doi/10.1016/j.fct.2017.05.034
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, cis-3-octen-1-ol, CAS Registry Number 20125-84-2
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S611-S618
info:doi/10.1016/j.fct.2017.10.015
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, cis-6-nonen-1-ol, CAS Registry Number 35854-86-5
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S577-S584
info:doi/10.1016/j.fct.2017.09.059
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, Citronellyl nitrile, CAS Registry Number 51566-62-2
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S383-S391
info:doi/10.1016/j.fct.2017.07.043
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, cuminyl nitrile, CAS Registry Number 13816-33-6
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S179-S186
info:doi/10.1016/j.fct.2017.04.042
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, cyclohexanecarboxylic acid, 1,4-dimethyl-, methyl ester, trans- CAS Registry Number 23250-42-2
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S726-S734
info:doi/10.1016/j.fct.2017.11.017
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Bhatia, S.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Kromidas, L.; La Cava, S.; Lalko, J.; Lapczynski, A.; Liebler, D.C.; Miyachi, Y.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Politano, V.T.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.; Wall, B.; Wilcox, D.K.:
RIFM Fragrance Ingredient Safety Assessment, d-Cyclocitronellene acetate, CAS Registry Number 25225-10-9
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S66-S77
info:doi/10.1016/j.fct.2017.03.004
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, decanal dimethyl acetal, CAS Registry Number 7779-41-1
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S679-S686
info:doi/10.1016/j.fct.2017.10.049
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Bhatia, S.; Botelho, D.; Browne, D.; Bruze, M.; Burton, A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; Kromidas, L.; La Cava, S.; Lalko, J.F.; Lapczynski, A.; Liebler, D.C.; Miyachi, Y.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Politano, V.T.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.; Wall, B.; Wilcox, D.K.:
RIFM fragrance ingredient safety assessment, dihydro-α-terpineol, CAS Registry Number 498-81-7
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S253-S262
info:doi/10.1016/j.fct.2017.05.063
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, dihydro-β-ionol, cas registry number 3293-47-8
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement, pp.S654-S661
info:doi/10.1016/j.fct.2017.10.010
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Bhatia, S.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; Kromidas, L.; La Cava, S.; Lalko, J.F.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Politano, V.T.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.; Wall, B.; Wilcox, D.K.:
RIFM fragrance ingredient safety assessment, elemol, CAS Registry Number 639-99-6
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S16-S21
info:doi/10.1016/j.fct.2016.11.027
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, Ethyl 2,3,6-trimethylcyclohexyl carbonate, CAS Registry Number 93981-50-1
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S718-S725
info:doi/10.1016/j.fct.2017.11.012
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, ethyl 2-tert-butylcyclohexyl carbonate, CAS Registry Number 67801-64-3
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S502-S511
info:doi/10.1016/j.fct.2017.09.033
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, ethylene dodecanedioate, CAS registry number 54982-83-1
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S670-S678
info:doi/10.1016/j.fct.2017.10.050
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, α-Isobutylphenethyl alcohol, CAS Registry Number 7779-78-4
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S637-S644
info:doi/10.1016/j.fct.2017.10.012
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, isoamyl acetate, CAS Registry Number 123-92-2
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S123-S132
info:doi/10.1016/j.fct.2017.03.046
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, isoamyl alcohol CAS Registry Number 123-51-3
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S421-S430
info:doi/10.1016/j.fct.2017.08.015
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, Isoamyl butyrate, CAS Registry Number 106-27-4
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S187-S197
info:doi/10.1016/j.fct.2017.05.016
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, isoamyl formate, CAS Registry Number 110-45-2
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S142-S150
info:doi/10.1016/j.fct.2017.04.013
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, isoamyl hexanoate, CAS Registry Number 2198-61-0
Food and Chemical Toxicology : FCT, Vol.110 (2017), pp.S114-S122
info:doi/10.1016/j.fct.2017.03.040
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, Isoamyl octanoate, CAS Registry Number 2035-99-6
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S39-S48
info:doi/10.1016/j.fct.2017.02.036
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, isoamyl propionate, CAS Registry Number 105-68-0
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S86-S94
info:doi/10.1016/j.fct.2017.03.021
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, isobutyl N-methylanthranilate, CAS Registry Number 65505-24-0
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S375-S382
info:doi/10.1016/j.fct.2017.07.045
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, isodecyl alcohol, CAS registry number 25339-17-7
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S337-S343
info:doi/10.1016/j.fct.2017.06.027
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Bhatia, S.; Botelho, D.; Brown, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Fryer, A.D.; Kromidas, L.; Lalko, J.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Politano, V.T.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Thakkar, Y.; Wahler, J.; Wall, B.; Wilcox, D.K.:
RIFM fragrance ingredient safety assessment, Isolongifolene ketone, CAS registry number 23787-90-8
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S59-S65
info:doi/10.1016/j.fct.2017.02.034
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, isononyl propionate, CAS Registry Number 65155-45-5
Food and Chemical Toxicology : FCT, Vol.110 (2017), s, pp.S133-S141
info:doi/10.1016/j.fct.2017.04.015
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, isotridecyl acetate, CAS registry number 69103-23-7
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S78-S85
info:doi/10.1016/j.fct.2017.03.003
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, l-Cyclocitronellene formate, CAS Registry Number 25225-08-5
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S49-S58
info:doi/10.1016/j.fct.2017.02.035
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; Cava, S. la; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, menthyl acetate (isomer unspecified), CAS Registry Number 16409-45-3
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S619-S628
info:doi/10.1016/j.fct.2017.10.014
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, menthyl isovalerate CAS Registry Number 16409-46-4
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S486-S495
info:doi/10.1016/j.fct.2017.09.035
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, methyl anthranilate, CAS Registry Number 134-20-3
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S290-S298
info:doi/10.1016/j.fct.2017.06.003
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Bhatia, S.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; Kromidas, L.; La Cava, S.; Lalko, J.F.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Politano, V.T.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.; Wall, B.; Wilcox, D.K.:
RIFM fragrance ingredient safety assessment, Methyl hexyl oxo cyclopentanone carboxylate, CAS Registry Number 37172-53-5
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S327-S336
info:doi/10.1016/j.fct.2017.06.028
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Bhatia, S.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; Kromidas, L.; La Cava, S.; Lalko, J.F.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Politano, V.T.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.; Wall, B.; Wilcox, D.K.:
RIFM FRAGRANCE INGREDIENT SAFETY ASSESSMENT, Methyl jasmonate, CAS Registry Number 1211-29-6
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S104-S113
info:doi/10.1016/j.fct.2017.03.035
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, methyl N-acetylanthranilate, CAS Registry Number 2719-08-6
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S210-S221
info:doi/10.1016/j.fct.2017.05.030
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, Methylcyclooctyl carbonate, CAS Registry Number 61699-38-5
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S561-S568
info:doi/10.1016/j.fct.2017.09.046
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, oxacyclohexadecane-2,13-dione, CAS Registry Number 38223-29-9
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S711-S717
info:doi/10.1016/j.fct.2017.11.013
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, p-(2,2-dimethoxyethyl)toluene, CAS Registry Number 42866-91-1
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S455-S461
info:doi/10.1016/j.fct.2017.08.034
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, p-methoxybenzonitrile, CAS Registry Number 874-90-8
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S351-S357
info:doi/10.1016/j.fct.2017.07.004
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, phenylacetaldehyde diethyl acetal, CAS Registry Number 6314-97-2
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S431-S438
info:doi/10.1016/j.fct.2017.08.039
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Botelho, D.; Browne, D.; Bruze, M.; Burton, G.A.; Buschmann, J.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A.D.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D.C.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Sipes, I.G.; Thakkar, Y.; Theophilus, E.H.; Tiethof, A.K.; Tokura, Y.; Tsang, S.; Wahler, J.:
RIFM fragrance ingredient safety assessment, propyl phenethyl acetal, CAS Registry Number 7493-57-4
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S512-S520
info:doi/10.1016/j.fct.2017.09.030
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Bhatia, S.; Botelho, D.; Browne, D.; Bruze, M.; Burton, A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; Kromidas, L.; La Cava, S.; Lalko, J.F.; Lapczynski, A.; Liebler, D.C.; Miyachi, Y.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Politano, V.T.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.; Wall, B.; Wilcox, D.K.:
RIFM fragrance ingredient safety assessment, terpineol, CAS Registry Number 8000-41-7
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S392-S402
info:doi/10.1016/j.fct.2017.07.042
Fraunhofer ITEM


Api, A.M.; Belsito, D.; Bhatia, S.; Botelho, D.; Browne, D.; Bruze, M.; Burton, A.; Buschmann, J.; Calow, P.; Dagli, M.L.; Date, M.; Dekant, W.; Deodhar, C.; Fryer, A.D.; Joshi, K.; Kromidas, L.; Cava, S. la; Lalko, J.F.; Lapczynski, A.; Liebler, D.C.; Miyachi, Y.; O'Brien, D.; Parakhia, R.; Patel, A.; Penning, T.M.; Politano, V.T.; Ritacco, G.; Romine, J.; Salvito, D.; Schultz, T.W.; Shen, J.; Sipes, I.G.; Thakkar, Y.; Tokura, Y.; Tsang, S.; Wahler, J.; Wall, B.; Wilcox, D.K.:
RIFM fragrance ingredient safety assessment, tetrahydro-4-methyl-2-(2-methylpropen-1-yl)pyran, CAS Registry Number 16409-43-1
Food and Chemical Toxicology : FCT, Vol.110 (2017), Supplement 1, pp.S645-S653
info:doi/10.1016/j.fct.2017.10.011
Fraunhofer ITEM


Niehof, Monika; Hildebrandt, Tobias; Danov, Olga; Arndt, Kirsten; Koschmann, Jeannette; Dahlmann, Franziska; Hansen, Tanja; Sewald, Katherina:
RNA isolation from precision-cut lung slices (PCLS) from different species
BMC research notes. Online journal, Vol.10 (2017), Art. 121, 10 pp.
urn:nbn:de:0011-n-4878753
info:doi/10.1186/s13104-017-2447-6
Volltext
Fraunhofer ITEM


Behr, Jürgen; Günther, Andreas; Bonella, Francesco; Geißler, Klaus; Koschel, Dirk; Kreuter, Michael; Prasse, Antje; Schönfeld, Nicolas; Sitter, Helmut; Müller-Quernheim, Joachim; Costabel, Ulrich:
S2k-Leitlinie Idiopathische Lungenfibrose - Update zur medikamentösen Therapie 2017
Pneumologie, Vol.71 (2017), No.7, pp.460-474
info:doi/10.1055/s-0043-106160
Fraunhofer ITEM


Badorrek, Philipp; Müller, Meike; Koch, Wolfgang; Hohlfeld, Jens M.; Krug, Norbert:
Specificity and reproducibility of nasal biomarkers in patients with allergic rhinitis after allergen challenge chamber exposure
Annals of allergy, asthma, & immunology, Vol.118 (2017), No.3, pp.290-297
urn:nbn:de:0011-n-4459593
info:doi/10.1016/j.anai.2017.01.018
Volltext
Fraunhofer ITEM


Milesi, Ilaria; Tingay, David G.; Lavizzari, Anna; Bianco, Federico; Zannin, Emanuela; Tagliabue, Paolo; Mosca, Fabio; Ventura, Maria L.; Rajapaksa, Anushi; Perkins, Elizabeth J.; Black, Don; Castri, Marco di; Sourial, Magdi; Pohlmann, Gerhard; Dellaca, Raffaele L.:
Supraglottic Atomization of Surfactant in Spontaneously Breathing Lambs Receiving Continuous Positive Airway Pressure
Pediatric critical care medicine, Vol.18 (2017), No.9, pp.E428-E434
info:doi/10.1097/PCC.0000000000001267
Fraunhofer ITEM


Steffen, L.; Ruppert, C.; Hoymann, H.-G.; Funke, M.; Ebener, S.; Kloth, C.; Mühlfeld, C.; Ochs, M.; Knudsen, L.; Lopez-Rodriguez, E.:
Surfactant replacement therapy reduces acute lung injury and collapse induration-related lung remodeling in the bleomycin model
American journal of physiology. L, Lung cellular and molecular physiology, Vol.313 (2017), No.2, pp.L313-L327
info:doi/10.1152/ajplung.00033.2017
Fraunhofer ITEM


Schwarz, K.; Koch, W.:
Thoracic and respirable aerosol fractions of spray products containing non-volatile compounds
Journal of occupational and environmental hygiene, Vol.14 (2017), No.10, pp.831-838
info:doi/10.1080/15459624.2017.1335403
Fraunhofer ITEM


Schupp, J.C.; Vukmirovic, M.; Kaminski, N.; Prasse, A.:
Transcriptome profiles in sarcoidosis and their potential role in disease prediction
Current opinion in pulmonary medicine, Vol.23 (2017), No.5, pp.487-492
info:doi/10.1097/MCP.0000000000000403
Fraunhofer ITEM


Kuo, C.H.S.; Pavlidis, S.; Loza, M.; Baribaud, F.; Rowe, A.; Pandis, I.; Hoda, U.; Rossios, C.; Souse, A.; Wilson, S.J.; Howarth, P.; Dahlen, B.; Dahlen, S.E.; Chanez, P.; Shaw, D.; Krug, Norbert; Sandström, T.; Meulder, B. de; Lefaudeux, D.; Fowler, S.; Fleming, L.; Corfield, J.; Auffray, C.; Sterk, P.J.; Djukanovic, R.; Guo, Y.K.; Adcock, I.M.; Chung, K.F.:
A Transcriptome-driven Analysis of Epithelial Brushings and Bronchial Biopsies to Define Asthma Phenotypes in U-BIOPRED
American Journal of Respiratory and Critical Care Medicine, Vol.195 (2017), No.4, pp.443-455
info:doi/10.1164/rccm.201512-2452OC
Fraunhofer ITEM


Schrom, E.; Huber, M.; Aneja, M.; Dohmen, C.; Emrich, D.; Geiger, J.; Hasenpusch, G.; Herrmann-Janson, A.; Kretzschmann, V.; Mykhailyk, O.; Pasewald, T.; Oak, P.; Hilgendorff, A.; Wohlleber, D.; Hoymann, H.-G.; Schaudien, D.; Plank, C.; Rudolph, C.; Kubisch-Dohmen, R.:
Translation of angiotensin-converting enzyme 2 upon liver- and lung-targeted delivery of optimized chemically modified mRNA
Molecular therapy. Nucleic Acids, Vol.7 (2017), pp.350-365
info:doi/10.1016/j.omtn.2017.04.006
Fraunhofer ITEM


Lefaudeux, D.; De Meulder, B.; Loza, M.J.; Peffer, N.; Rowe, A.; Baribaud, F.; Bansal, A.T.; Lutter, R.; Sousa, A.R.; Corfield, J.; Pandis, I.; Bakke, P.S.; Caruso, M.; Chanez, P.; Dahlén, S.-E.; Fleming, L.J.; Fowler, S.J.; Horvath, I.; Krug, N.; Montuschi, P.; Sanak, M.; Sandstrom, T.; Shaw, D.E.; Singer, F.; Sterk, P.J.; Roberts, G.; Adcock, I.M.; Djukanovic, R.; Auffray, C.; Chung, K.F.:
U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics
The journal of allergy and clinical immunology : JACI, Vol.139 (2017), No.6, pp.1797-1807
info:doi/10.1016/j.jaci.2016.08.048
Fraunhofer ITEM


Tongeren, M. van; Lamb, J.; Cherrie, J.W.; MacCalman, L.; Basinas, I.; Hesse, S.:
Validation of Lower Tier Exposure Tools Used for REACH: Comparison of Tools Estimates With Available Exposure Measurements
Annals of work exposures and health, Vol.61 (2017), 8, pp.921-938
info:doi/10.1093/annweh/wxx056
Fraunhofer ITEM