Bludau, E.:
Untersuchungen zur Leistungsfähigkeit von Zelllinien mit Kassettenaustauschsystem
Braunschweig, TU, Diss., 2015
urn:nbn:de:gbv:084-15052111467
Fraunhofer ITEM


Ritter, Detlef; Krakor, E.; Knebel, Jan:
Acute inhalation toxicity of volatile organic compounds - application of an improved cell-based in vitro procedure. (Society of Toxicology (Annual Meeting) <54, 2015, San Diego/Calif.>)
The Toxicologist, Vol.54 (2015), No.1, pp.50, Abstract PS 238
Fraunhofer ITEM Ritter (Publica)


Ritter, Detlef; Knebel, Jan:
Acute toxicity testing of inhalable/gaseous compounds by cell-based methods in vitro - application to volatile organic compounds. (European Societies of Toxicology (EUROTOX Congress) <51, 2015, Porto>)
Toxicology letters, Vol.238 (2015), No.2, Supplement, pp.S178, Abstract P07-016
info:doi/10.1016/j.toxlet.2015.08.517
Fraunhofer ITEM


Krug, Norbert; Hohlfeld, Jens Michael; Kirsten, Anne-Marie; Kornmann, Oliver; Beeh, Kai-Michael; Kappeler, Dominik; Korn, Stephanie; Ignatenko, Stanislav; Timmer, Wolfgang; Rogon, Cordelia; Zeitvogel, Jana; Zhang, Nan; Bille, Joachim; Homburg, Ursula; Turowska, Agnieszka; Bachert, Claus; Werfel, Thomas; Buhl, Roland; Renz, Jonas; Garn, Holger; Renz, Harald:
Allergen-induced asthmatic responses modified by a GATA3-specific DNAzyme
The New England journal of medicine, Vol.372 (2015), No.21, pp.1987-1995
info:doi/10.1056/NEJMoa1411776
Fraunhofer ITEM Krug (Publica)


Pohlmann, G.; Hohlfeld, J.; Pankalla, J.:
Assessing the breathing capability of patients through inhalers. (International Society for Aerosols in Medicine (ISAM International Congress) <20, 2015, Munich>)
Journal of aerosol medicine and pulmonary drug delivery, Vol.28 (2015), No.3, pp.A16
Fraunhofer ITEM


Guerard, M.; Baum, M.; Bitsch, Annette; Eisenbrand, G.; Elhajouji, A.; Epe, B.; Habermeyer, M.; Kaina, B.; Martus, H.J.; Pfuhler, S.; Schmitz, C.; Sutter, A.; Thomas, A.D.; Ziemann, Christina; Froetschl, R.:
Assessment of mechanisms driving non-linear dose-response relationships in genotoxicity testing
Mutation research. Reviews, Vol.763 (2015), pp.181-201
info:doi/10.1016/j.mrrev.2014.11.001
Fraunhofer ITEM Bitsch (Publica)


Kock, Heiko; Civic, Terence; Koch, Wolfgang:
Beryllium concentrations at european workplaces: Comparison of 'total' and inhalable particulate measurements
The Annals of occupational hygiene, Vol.59 (2015), No.6, pp.788-796
urn:nbn:de:0011-n-3476657
info:doi/10.1093/annhyg/mev009
Volltext
Fraunhofer ITEM Kock (Publica)


Koch, W.; Kock, H.; Civic, T.:
Beryllium concentrations at European workplaces: Comparison of ‘total’ and inhalable particulate measurements. (International Society for Aerosols in Medicine (ISAM International Congress) <20, 2015, Munich>)
Journal of aerosol medicine and pulmonary drug delivery, Vol.28 (2015), No.3, pp.A28
Fraunhofer ITEM


Hackbarth, Anja; Steinberg, Pablo (Wiss. Betreuer); Dasenbrock, Clemens (Wiss. Betreuer); Steinberg, Pablo (1. Gutachter); Kietzmann, Manfred (2. Gutachter) :
Biologische Wirkungen synthetisch hergestellter Multiwall-Carbon-Nanotubes am Tiermodell und in der Zellkultur
Hannover, Tierärztliche Hochschule, Diss., 2015
Fraunhofer ITEM Hackbarth (Publica)


Hohlfeld, Jens Michael; Furtwaengler, A.; Könen-Bergmann, M.; Wallenstein, G.; Walter, B.; Bateman, E.D.:
Cardiac safety of tiotropium in patients with COPD: A combined analysis of Holter-ECG data from four randomised clinical trials
The international journal of clinical practice : IJCP, Vol.69 (2015), No.1, pp.72-80
info:doi/10.1111/ijcp.12596
Fraunhofer ITEM Hohlfeld (Publica)


Requardt, H.; Hansen, T.; Eisenbarth, E.; Hampel, S.; Dasenbrock, C.:
Cellular uptake of different nano and bulk metal oxide particles by cells derived from epidermal, intestinal and leukocyte cell lines. (Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie (Annual Meeting) <81, 2015, Kiel>)
Naunyn-Schmiedebergs archives of pharmacology, Vol.388 (2015), pp.71
Fraunhofer ITEM


Schwarz, Katharina; Biller, Heike; Windt, Horst; Koch, Wolfgang; Hohlfeld, Jens M.:
Characterization of exhaled particles from the human lungs in airway obstruction
Journal of aerosol medicine and pulmonary drug delivery, Vol.28 (2015), No.1, pp.52-58
info:doi/10.1089/jamp.2013.1104
Fraunhofer ITEM Schwarz (Publica)


Burg, Bart van der; Bay Wedebye, Eva; Dietrich, Daniel R.; Jaworska, Joanna; Mangelsdorf, Inge; Paune, Eduard; Schwarz, Michael; Piersma, Aldert H.:
The ChemScreen project to design a pragmatic alternative approach to predict reproductive toxicity of chemicals
Reproductive toxicology, Vol.55 (2015), pp.114-123
info:doi/10.1016/j.reprotox.2015.01.008
Fraunhofer ITEM Mangelsdorf (Publica)


Toncheva, A.A.; Potaczek, D.P.; Schedel, M.; Gersting, S.W.; Michel, S.; Krajnov, N.; Gaertner, V.D.; Klingbeil, J.M.; Illig, T.; Franke, A.; Winkler, Carla; Hohlfeld, Jens M.; Vogelberg, C.; Berg, A. von; Bufe, A.; Heinzmann, A.; Laub, O.; Rietschel, E.; Simma, B.; Genuneit, J.; Muntau, A.C.; Kabesch, Michael:
Childhood asthma is associated with mutations and gene expression differences of ORMDL genes that can interact
Allergy. European journal of allergy and clinical immunology, Vol.70 (2015), No.10, pp.1288-1299
info:doi/10.1111/all.12652
Fraunhofer ITEM Winkler (Publica)


Deckmann, Klaus; Krasteva-Christ, Gabriela; Rafiq, Amir; Herden, Christine; Wichmann, Judy; Knauf, Sascha; Nassenstein, Christina; Grevelding, Christoph G.; Dorresteijn, Adriaan; Chubanov, Vladimir; Gudermann, Thomas; Bschleipfer, Thomas; Kummer, Wolfgang:
Cholinergic urethral brush cells are widespread throughout placental mammals. (International Symposium on Non-Neuronal Acetylcholine (NNACh) <4, 2014, Gießen>)
International immunopharmacology, Vol.29 (2015), No.1, pp.51-56
info:doi/10.1016/j.intimp.2015.05.038
Fraunhofer ITEM


Obernolte, Helena; Konzok, Sebastian; Ritter, Detlef; Knebel, Jan; Braubach, Peter; Jonigk, Danny; Fieguth, Hans-Gerd; Braun, Armin; Sewald, Katherina:
Cigarette smoke and cigarette smoke condensate exposure induces cytotoxicity and inflammation in precision-cut lung slices. (European Societies of Toxicology (EUROTOX Congress) <51, 2015, Porto>)
Toxicology letters, Vol.238 (2015), No.2, Supplement, pp.S329-S330
info:doi/10.1016/j.toxlet.2015.08.940
Fraunhofer ITEM


Obernolte, Helena; Ritter, Detlef; Knebel, Jan W.; Braubach, Peter; Jonigk, Danny; Braun, Armin; Sewald, Katherina:
Cigarette smoke and cigarette smoke condensate induce cell injury and early biomarkers of inflammation in human and rodent Precision-Cut Lung Slices. (European Congress on Alternatives to Animal Testing <19, 2015, Linz>)
ALTEX Proceedings, Vol.4 (2015), No.2, pp.173
Fraunhofer ITEM


Obernolte, Helena; Konzok, Sebastian; Ritter, Detlef; Knebel, Jan W.; Braubach, Peter; Jonigk, Danny; Braun, Armin; Sewald, Katherina:
Cigarette smoke condensate and cigarette smoke induce cytotoxicity and inflammation in human and rodent Precision-Cut Lung Slices of different species. (International Symposium "Frontiers in Chronic and Malignant Airways Disease" <4, 2015, Heidelberg>)
Pneumologie, Vol.69 (2015), No.7, pp.69 - A17
info:doi/10.1055/s-0035-1556609
Fraunhofer ITEM


Shaw, Dominick E.; Sousa, Ana R.; Fowler, Stephen J.; Fleming, Louise J.; Roberts, Graham; Corfield, Julie; Pandis, Ioannis; Bansal, Aruna T.; Bel, Elisabeth H.; Auffray, Charles; Compton, Chris H.; Bisgaard, Hans; Bucchioni, Enrica; Caruso, Massimo; Chanez, Pascal; Dahlén, Barbro; Dahlén, Sven-Erik; Dyson, Kerry; Frey, Urs; Geiser, Thomas; Gerhardsson de Verdier, Maria; Gibeon, David; Guo, Yi-Ke; Hashimoto, Simone; Hedlin, Gunilla; Jeyasingham, Elizabeth; Hekking, Pieter-Paul W.; Higenbottam, Tim; Horváth, Ildikó; Knox, Alan J.; Krug, Norbert; Erpenbeck, Veit J.; Larsson, Lars X.; Lazarinis, Nikos; Matthews, John G.; Middelveld, Roelinde; Montuschi, Paolo; Musial, Jacek; Myles, David; Pahus, Laurie; Sandström, Thomas; Seibold, Wolfgang; Singer, Florian; Strandberg, Karin; Vestbo, Jorgen; Vissing, Nadja; Garnier, Christophe von; Adcock, Ian M.; Wagers, Scott; Rowe, Anthony; Howarth, Peter; Wagener, Ariane H.; Djukanovic, Ratko; Sterk, Peter J.; Chung, Kian Fan:
Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort
European Respiratory Journal, Vol.46 (2015), No.5, pp.1308-1321
info:doi/10.1183/13993003.00779-2015
Fraunhofer ITEM Krug (Publica)


Steger-Hartmann, T.; Pognan, F.; Sanz, F.; Briggs, K.; Escher, Sylvia; Kleinoeder, T.; Schwab, C.; Wichard, J.; Yang, C.:
Comparative data-mining across multiple toxicity databases harmonized by eTOX ontology to test hypotheses. (Society of Toxicology (Annual Meeting) <54, 2015, San Diego/Calif.>)
The Toxicologist, Vol.54 (2015), No.1, pp.478, Abstract PS 2226
Fraunhofer ITEM Escher (Publica)


Hoymann, Heinz-G.; Schaudien, Dirk; Hansen, Tanja; Müller, Meike; Braun, Armin:
Comparison of fibrotic and emphysematous alterations in the lungs of bleomycin-treated rats and hamsters. (American Thoracic Society (ATS International Conference) <2015, Denver/Colo.>)
American Journal of Respiratory and Critical Care Medicine, Vol.191 (2015), Art. A3454
Fraunhofer ITEM


Juling, S.; Lichtenstein, D.; Selve, S.; Oberemm, A.; Creutzenberg, Otto; Braeuning, A.; Lampen, A.:
Comparison of two different application routes of nanosilver in rats - evidence for nanoparticles after silver ion treatment. (Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie (Annual Meeting) <81, 2015, Kiel>)
Naunyn-Schmiedebergs archives of pharmacology, Vol.388 (2015), Supplement 1, pp.S69, Abstract 273
Fraunhofer ITEM Creutzenberg (Publica)


Holz, Olaf; Roepcke, Stefan; Watz, Henrik; Tegtbur, Uwe; Lahu, Gezim; Hohlfeld, Jens Michael:
Constant-load exercise decreases the serum concentration of myeloperoxidase in healthy smokers and smokers with COPD
International journal of chronic obstructive pulmonary disease, Vol.10 (2015), No.1, pp.1393-1402
urn:nbn:de:0011-n-3563748
info:doi/10.2147/COPD.S83269
Volltext
Fraunhofer ITEM Holz (Publica)


Sullivan, K.; Cochrane, S.; Enoch, S.J.; Ezendam, J.; Patlewicz, G.; Roggen, E.L.; Sewald, Katherina:
Constructing an adverse outcome pathway for sensitization of the respiratory tract: Network thinking meets regulatory utility. (Society of Toxicology (Annual Meeting) <54, 2015, San Diego/Calif.>)
The Toxicologist, Vol.54 (2015), No.1, pp.142, Abstract PS 666
Fraunhofer ITEM Sewald (Publica)


Solecki, Roland; Rauch, Martina; Gall, Andrea; Buschmann, Jochen; Clark, Ruth; Fuchs, Antje; Kan, Haidong; Heinrich, Verena; Kellner, Rupert; Knudsen, Thomas B.; Li, Weihua; Makris, Susan L.; Ooshima, Yojiro; Paumgartten, Francisco; Piersma, Aldert H.; Schönfelder, Gilbert; Oelgeschläger, Michael; Schaefer, Christof; Shiota, Kohei; Ulbrich, Beate; Ding, Xuncheng; Chahoud, Ibrahim:
Continuing harmonization of terminology and innovations for methodologies in developmental toxicology: Report of the 8th Berlin Workshop on Developmental Toxicity, 14-16 May 2014
Reproductive toxicology, Vol.57 (2015), pp.140-146
info:doi/10.1016/j.reprotox.2015.06.046
Fraunhofer ITEM


Heratizadeh, A.; Badorrek, P.; Kapp, A.; Niebuhr, M.; Roesner, L.M.; Karch, A.; Erpenbeck, V.J.; Loesche, C.; Jung, T.; Krug, N.; Hohlfeld, J.M.; Werfel, T.:
Controlled exposure to grass pollen in an environmental challenge chamber induces a worsening of cutaneous symptoms in patients with atopic dermatitis. (European Academy of Allergy and Clinical Immunology (Congress) <2015, Barcelona>)
Allergy. European journal of allergy and clinical immunology, Vol.70 (2015), Supplement S101, pp.589-590
Fraunhofer ITEM


Wink, S.; Water, B. van de; Reif, R.; Hammad, S.; Stöber, R.; Widera, A.; Hengstler, J.; Limonciel, A.; Jennings, P.; Escher, S.; Keun, H.; Kleinjans, J.; Kopp-Schneider, A.; Peterson, H.; Ringwald, A.; Rogiers, V.; Sachinidis, A.; Sickmann, A.; Vinken, M.; Spitkovsky, D.; Hescheler, J.:
DETECTIVE: Detection of Endpoints and Biomarkers for Repeated Dose Toxicity using in vitro Systems
Gocht, T.: Towards the replacement of in vivo repeated dose systemic toxicity testing. Vol. 5: Mechanism-based methods for improved toxicity testing. Paris: Arttic, 2015. (SEURAT-1 Annual report), pp. 136-165
Fraunhofer ITEM


Hohlfeld, J.M.; Lüer, K.; Holz, O.; Häfner, D.; Koch, W.; Krug, N.:
Determination of markers that predict the individual response of perennial allergic subjects to house dust mite allergen in the Fraunhofer Environmental Challenge Chamber (ECC). (European Academy of Allergy and Clinical Immunology (Congress) <2015, Barcelona>)
Allergy. European journal of allergy and clinical immunology, Vol.70 (2015), Supplement S101, pp.29-30
Fraunhofer ITEM


Czyz, Zbigniew Tadeusz; Klein, Christoph A.:
Deterministic whole-genome amplification of single cells
Kroneis, Thomas (Ed.): Whole genome amplification: Methods and protocols. New York: Springer Science+Business Media, 2015. (Methods in molecular biology 1347), pp. 69-86
info:doi/10.1007/978-1-4939-2990-0_5
Fraunhofer ITEM Czyz (Publica)


Granitzny, Anne; Hansen, Tanja; Knebel, Jan W.; Dasenbrock, Clemens; Steinberg, Pablo:
Development of a co-culture model for the prediction of idiosyncratic drug-induced liver injury. (Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie (Annual Meeting) <81, 2015, Kiel>)
Naunyn-Schmiedebergs archives of pharmacology, Vol.388 (2015), Supplement 1, pp.S65, Abstract 257
Fraunhofer ITEM Granitzny (Publica)


Konzok, Sebastian; Schindler, Susann; Jonigk, Danny; Braubach, Peter; Braun, Armin; Sewald, Katherina:
Development of a human organotypic tumor invasion model of cancer cell line MDA-MB-231 in Precision-Cut Lung Slices (PCLS). (International Symposium "Frontiers in Chronic and Malignant Airways Disease" <4, 2015, Heidelberg>)
Pneumologie, Vol.69 (2015), No.7, Art. A73
info:doi/10.1055/s-0035-1556665
Fraunhofer ITEM Konzok (Publica)


Escher, S.; Hengstler, J.:
Development of Biomarker Based on a Read-Across Use Case on Valproic Acid Analogues
Gocht, T.: Towards the replacement of in vivo repeated dose systemic toxicity testing. Vol. 5: Mechanism-based methods for improved toxicity testing. Paris: Arttic, 2015. (SEURAT-1 Annual report), pp. 79-80
Fraunhofer ITEM


Bitsch, Annette; Batke, Monika; Gundert-Remy, U.; Gütlein, M.; Kramer, S.; Partosch, F.; Seeland, M.:
Development of chemical categories by optimized clustering strategies. (Society of Toxicology (Annual Meeting) <54, 2015, San Diego/Calif.>)
The Toxicologist, Vol.54 (2015), No.1, pp.480, Abstract PS 2236
Fraunhofer ITEM Bitsch (Publica)


Sewald, Katherina; Müller, Meike; Buschmann, Jochen; Hansen, Tanja; Lewin, Geertje:
Development of hematological and immunological characteristics in neonatal rats. (European Teratology Society (ETS Annual Conference) <43, 2015, Amsterdam>)
Reproductive toxicology, Vol.56 (2015), pp.109-117
info:doi/10.1016/j.reprotox.2015.05.019
Fraunhofer ITEM Sewald (Publica)


Waschki, Benjamin; Kirsten, Anne M.; Holz, Olaf; Müller, Kai-Christian; Schaper, Miriam; Sack, Anna-Lena; Meyer, Thorsten; Rabe, Klaus F.; Magnussen, Helgo; Watz, Henrik:
Disease progression and changes in physical activity in patients with chronic obstructive pulmonary disease
American Journal of Respiratory and Critical Care Medicine, Vol.192 (2015), No.3, pp.295-306
info:doi/10.1164/rccm.201501-0081OC
Fraunhofer ITEM


Tsai, P.P.; Schlichtig, A.; Ziegler, E.; Ernst, H.; Haberstroh, J.; Stelzer, H.D.; Hackbarth, H.:
Effects of different blood collection methods on indicators of welfare in mice
Lab animal, Vol.44 (2015), No.8, pp.301-310
Fraunhofer ITEM


Badorrek, Philipp; Hohlfeld, Jens M.; Krug, Norbert; Joshi, Abhijeet; Raut, Atul:
Efficacy and safety of a novel nasal steroid, S0597, in patients with seasonal allergic rhinitis
Annals of allergy, asthma, & immunology, Vol.115 (2015), No.4, pp.325-329.e1
urn:nbn:de:0011-n-3666436
info:doi/10.1016/j.anai.2015.07.016
Volltext
Fraunhofer ITEM Badorrek (Publica)


Holz, Olaf; Biller, Heike; Müller, Meike; Kane, Katie; Rosano, Molly; Hanrahan, John; Hava, David L.; Hohlfeld, Jens M.:
Efficacy and safety of inhaled calcium lactate PUR118 in the ozone challenge model - a clinical trial
BMC pharmacology & toxicology. Online journal, Vol.16 (2015), Art. 21, 10 pp.
urn:nbn:de:0011-n-3695802
info:doi/10.1186/s40360-015-0021-1
Volltext
Fraunhofer ITEM


Gruber-Dujardin, E.; Curths, Christoph; Bleyer, Martina; Taubert, S.; Bauer, N.; Moritz, A.; Dahlmann, Franziska; Braun, Armin; Knauf, Sascha; Kaup, Franz Josef:
Eosinophils of the marmoset monkey (callithrix jacchus). (American Thoracic Society (ATS International Conference) <2015, Denver/Colo.>)
American Journal of Respiratory and Critical Care Medicine, Vol.191 (2015), Art. A4230
Fraunhofer ITEM


May, M.; Schindler, C.; Jordan, J.; Park-Simon, T.; Hillemanns, P.:
Erste Erfahrungen mit der interdisziplinären Durchführung einer gynäko-onkologischen frühen klinischen Prüfung im neuen Clinical Research Center Hannover
Senologie, Vol.2 (2015), No.12
info:doi/10.1055/s-0035-1550538
Fraunhofer ITEM


Walter, Dorothee; Fischer, Monika; Pohlmann, Gerhard; Kemkowski, J.; Muynck, C. de; Dasenbrock, Clemens:
Establishment of a saline lavage model in the isolated perfused rat lung. (Society of Toxicology (Annual Meeting) <54, 2015, San Diego/Calif.>)
The Toxicologist, Vol.54 (2015), No.1, pp.397, Abstract PS 1851
Fraunhofer ITEM Walter (Publica)


Hohlfeld, Jens M.; Furtwängler, Armin; Könen-Bergmann, Michael; Wallenstein, Gudrun; Walter, Blate; Bateman, Eric D.:
Evaluating cardiac safety of tiotropium in patients with COPD: Combined analysis of Holter-ECG data from four trials. (Deutsche Gesellschaft für Pneumologie und Beatmungsmedizin (Kongress) <56, 2015, Berlin>)
Pneumologie, Vol.69 (2015), No.S01, Abstract P126
info:doi/10.1055/s-0035-1544634
Fraunhofer ITEM


Kroese, Dinant E.; Bosgra, Sieto; Buist, Harrie E.; Lewin, Geertje; Linden, Sander C. van der; Man, Hai-yen; Piersma, Aldert H.; Rorije, Emiel; Schulpen, Sjors H.W.; Schwarz, Michael; Uibel, Frederik; Vugt-Lussenburg, Barbara M.A. van; Wolterbeek, Andre P.M.; Burg, Bart van der:
Evaluation of an alternative in vitro test battery for detecting reproductive toxicants in a grouping context
Reproductive toxicology, Vol.55 (2015), pp.11-19
info:doi/10.1016/j.reprotox.2014.10.003
Fraunhofer ITEM Lewin (Publica)


Bernstein, David M.; Rogers, R.A.; Sepulveda, Rosalina; Kunzendorf, Peter; Bellmann, Bernd; Ernst, Heinrich; Creutzenberg, Otto H.; Phillips, James I.:
Evaluation of the fate and pathological response in the lung and pleura of brake dust alone and in combination with added chrysotile compared to crocidolite asbestos following short-term inhalation exposure
Toxicology and Applied Pharmacology, Vol.283 (2015), No.1, pp.20-34
urn:nbn:de:0011-n-3476626
info:doi/10.1016/j.taap.2014.12.012
Volltext
Fraunhofer ITEM Bellmann (Publica)


May, Martin; Schwarz, Katharina; Koch, Wolfgang; Bitsch, Annette:
Evaluation of the toxicity and data gaps of e-cigarette aerosol. (Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie (Annual Meeting) <81, 2015, Kiel>)
Naunyn-Schmiedebergs archives of pharmacology, Vol.388 (2015), Supplement 1, pp.S72, Abstract 285
Fraunhofer ITEM


Werfel, T.; Heratizadeh, A.; Niebuhr, M.; Kapp, A.; Roesner, L.M.; Karch, A.; Erpenbeck, V.J.; Lösche, C.; Jung, T.; Krug, N.; Badorrek, P.; Hohlfeld, J.M.:
Exacerbation of atopic dermatitis on grass pollen exposure in an environmental challenge chamber
The journal of allergy and clinical immunology : JACI, Vol.136 (2015), No.1, pp.96-103
info:doi/10.1016/j.jaci.2015.04.015
Fraunhofer ITEM


Ritter, Detlef; Knebel, Jan:
Expositionsapparat
2015
Fraunhofer ITEM


Curths, C.; Dahlmann, F.; Wichmann, J.; Becker, T.; Knauf, Y.; Kaup, F.-J.; Braun, A.; Knauf, S.:
Features of house-dust-mite induced asthma in marmoset monkeys. (European Academy of Allergy and Clinical Immunology (Congress) <2015, Barcelona>)
Allergy. European journal of allergy and clinical immunology, Vol.70 (2015), Supplement S101, pp.44-45
Fraunhofer ITEM


Schwarz, Katharina; Holthenrich, Dagmar; Bissantz, Kathrin; Ehni, Markus; Bitsch, Annette:
Foam spray application of biocides: Investigation into aerosol inhalation exposure
Gefahrstoffe, Reinhaltung der Luft, Vol.75 (2015), No.5, pp.183-189
Fraunhofer ITEM Schwarz (Publica)


Fraunhofer-Institut für Toxikologie und Experimentelle Medizin -ITEM-, Hannover:
Fraunhofer-Institut für Toxikologie und Experimentelle Medizin. Leistungen und Ergebnisse. Jahresbericht 2014
Hannover: Fraunhofer ITEM, 2015
urn:nbn:de:0011-n-3496466
Volltext
Fraunhofer ITEM


Terracciano, M.; Buson, G.; Forcato, C.; Luca, F. de; Galardi, F.; Sero, V.; Pestrin, M.; Gabellini, S.; Koestler, C.; Czyz, Z.T.; Bregola, G.; Tononi, P.; Bolognesi, C.; Fontana, F.; Medoro, G.; Polzer, B.; Leo, A. di; Klein, C.A.; Manaresi, N.:
The genetic heterogeneity of circulating tumor cells: a longitudinal study in breast cancer patients. (European Cancer Congress)
European journal of cancer : EJC , Vol.51 (2015), pp.S39
Fraunhofer ITEM


Burg, Bart van der; Pieterse, Bart; Buist, Harrie E.; Lewin, Geertje; Linden, Sander C. van der; Man, Hai-yen; Rorije, Emiel; Piersma, Aldert H.; Mangelsdorf, Inge; Wolterbeek, Andre P.M.; Kroese, Dinant E.; Vugt-Lussenburg, Barbara van:
A high throughput screening system for predicting chemically-induced reproductive organ deformities
Reproductive toxicology, Vol.55 (2015), pp.95-103
info:doi/10.1016/j.reprotox.2014.11.011
Fraunhofer ITEM Lewin (Publica)


Curths, Christoph; Dahlmann, Franziska; Wichmann, Judy; Becker, Tamara; Knauf, Y.; Kaup, Franz-Josef; Braun, Armin; Knauf, Sascha:
House-dust-mite induced features of asthma in marmoset monkeys. (American Thoracic Society (ATS International Conference) <2015, Denver/Colo.>)
American Journal of Respiratory and Critical Care Medicine, Vol.191 (2015), Art. A4228
Fraunhofer ITEM


Liu, Wenzhong; Xie, Yubin; Ma, Jiyong; Luo, Xiaotong; Nie, Peng; Zuo, Zhixiang; Lahrmann, Urs; Zhao, Qi; Zheng, Yueyuan; Zhao, Yong; Xue, Yu; Ren, Jian:
IBS: An illustrator for the presentation and visualization of biological sequences
Bioinformatics, Vol.31 (2015), No.20, pp.3359-3361
info:doi/10.1093/bioinformatics/btv362
Fraunhofer ITEM Lahrmann (Publica)


Polzer, B.; Guzvic, M.; Ganzer, R.; Weckermann, D.; Braun, B.; Appel, I.; Obradovic, M.; Huppert, V.; Klein, C.A.:
Identification and molecular characterization of different subpopulations of EpCAM-positive single disseminated cancer cells in prostate cancer. (Metastasis Research Society (MRS International Biennial Congress) <15, 2014, Heidelberg>)
Clinical & experimental metastasis, Vol.32 (2015), No.3, pp.204-205
Fraunhofer ITEM


Prasse, Antje:
Die idiopathische Lungenfibrose
Pneumologie, Vol.69 (2015), No.10, pp.608-615
info:doi/10.1055/s-0034-1393036
Fraunhofer ITEM


Requardt, Hendrik; Hansen, Tanja; Eisenbarth, E.; Hampel, S.; Dasenbrock, Clemens:
In vitro toxicity testing of two multi-walled carbon nanotubes determined for the purpose of targeted drug delivery. (Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie (Annual Meeting) <81, 2015, Kiel>)
Naunyn-Schmiedebergs archives of pharmacology, Vol.388 (2015), Supplement 1, pp.S71, Abstract 282
Fraunhofer ITEM Requardt (Publica)


Rössig, Christina; Angrisani, Nina; Helmecke, Patrick; Besdo, Silke; Seitz, Jan-Marten; Welke, Bastian; Fedchenko, Nickolay; Kock, Heiko; Reifenrath, Janin:
In vivo evaluation of a magnesium-based degradable intramedullary nailing system in a sheep model
Acta biomaterialia, Vol.25 (2015), pp.369-383
info:doi/10.1016/j.actbio.2015.07.025
Fraunhofer ITEM Kock (Publica)


Danov, Olga; Escher, Sylvia E.; Schröder, Katrin; Vorgrimmler, David; Braubach, Peter; Jonigk, Danny; Warnecke, Gregor; Braun, Armin; Sewald, Katherina:
Induced cytotoxicity revealed species diversity of rat and human lung tissue by repeated chemical exposure. (European Congress on Alternatives to Animal Testing <19, 2015, Linz>)
ALTEX Proceedings, Vol.4 (2015), No.2, pp.53
Fraunhofer ITEM


Müller, Meike; Ziemann, Christina; Tillmann, Thomas; Lewin, Geertje; Dasenbrock, Clemens:
Influence of ELF-MF on the juvenile immune system of CD-1 mice. (Society of Toxicology (Annual Meeting) <54, 2015, San Diego/Calif.>)
The Toxicologist, Vol.54 (2015), No.1, pp.245, Abstract PS 1151
Fraunhofer ITEM Müller (Publica)


Hansen, Tanja; König, P.; Creutzenberg, Otto H.; Weinhold, K.; Schlick, S.; Tillmann, Thomas; Pohlmann, Gerhard; Kolling, Angelika; Ziemann, Christina; Kopf, Johannes; Ströbele, Michael; Bockhorn, H.; Danov, Olga; Sewald, Katherina; Müller, B.; Fehrenbach, Heinz:
Inhalation toxicity of carbon black depends on surface coating with polycyclic aromatic hydrocarbons. (Society of Toxicology (Annual Meeting) <54, 2015, San Diego/Calif.>)
The Toxicologist, Vol.54 (2015), No.1, pp.265, Abstract PS 1242
Fraunhofer ITEM Hansen (Publica)


Holz, Olaf; Tan, Lisa; Schaumann, Frank; Müller, Meike; Scholl, Dorothea; Hidi, R.; McLeod, Alison; Krug, Norbert; Hohlfeld, Jens M.:
Inter- and intrasubject variability of the inflammatory response to segmental endotoxin challenge in healthy volunteers
Pulmonary pharmacology & therapeutics, Vol.35 (2015), pp.50-59
info:doi/10.1016/j.pupt.2015.10.011
Fraunhofer ITEM Holz (Publica)


Keenan, C.M.; Baker, J.F.; Bradley, A.E.; Goodman, D.G.; Harada, T.; Herbert, R.; Kaufmann, W.; Kellner, R.; Mahler, B.; Meseck, E.; Nolte, T.; Rittinghausen, S.; Vahle, J.; Yoshizawa, K.:
International harmonization of nomenclature and diagnostic criteria (INHAND) progress to date and future plans
Journal of toxicologic pathology, Vol.28 (2015), No.1, pp.51-53
info:doi/10.1293/tox.2014-0049
Fraunhofer ITEM


Keenan, C.M.; Baker, J.; Bradley, A.; Goodman, D.G.; Harada, T.; Herbert, R.; Kaufmann, W.; Kellner, Rupert; Mahler, B.; Meseck, E.; Nolte, T.; Rittinghausen, Susanne; Vahle, J.; Yoshizawa, K.:
International harmonization of nomenclature and diagnostic criteria (INHAND): Progress to date and future plans
Toxicologic Pathology, Vol.43 (2015), No.5, pp.730-732
info:doi/10.1177/0192623314560031
Fraunhofer ITEM Kellner (Publica)


Alarcón, P.; Bohn, B.; Zetzsch, C.:
Kinetic and mechanistic study of the reaction of OH radicals with methylated benzenes: 1,4-dimethyl-, 1,3,5-trimethyl-, 1,2,4,5-, 1,2,3,5- and 1,2,3,4-tetramethyl-, pentamethyl-, and hexamethylbenzene
Physical chemistry, chemical physics : PCCP, Vol.17 (2015), No.19, pp.13053-13065
info:doi/10.1039/c5cp00253b
Fraunhofer ITEM


Czyz, Zbigniew Tadeusz; Stoecklein, Nikolas H.; Polzer, Bernhard:
Laser microdissection of FFPE tissue areas and subsequent whole genome amplification by Ampli1™
Kroneis, Thomas (Ed.): Whole genome amplification: Methods and protocols. New York: Springer Science+Business Media, 2015. (Methods in molecular biology 1347), pp. 141-162
info:doi/10.1007/978-1-4939-2990-0_11
Fraunhofer ITEM Czyz (Publica)


Sero, V.; Luca, F. de; Doffini, A.; Galardi, F.; Pestrin, M.; Czyz, Z.T.; Buson, G.; Bregola, G.; Bolognesi, C.; Fontana, F.; Medoro, G.; Polzer, B.; Leo, A. di; Klein, C.A.; Manaresi, N.:
Longitudinal genetic characterization of circulating tumor cells in metastatic breast cancer patients. (American Association for Cancer Research (AACR Annual Meeting) <106, 2015, Philadelphia/Pa.>)
Cancer research, Vol.75 (2015), No.15, Supplement, Abstract 371
info:doi/10.1158/1538-7445.AM2015-371
Fraunhofer ITEM


Klein, Christoph Andreas; Polzer, Bernhard Michael; Manaresi, Nicolo:
Method and kit for determining the genome integrity and/or the quality of a library of DNA-sequences otained by deterministic restriction site whole genome amplification
2015
Fraunhofer ITEM


Creutzenberg, Otto H.; Hansen, Tanja; Schuchardt, Sven; Tillmann, Thomas:
Method for identification of low soluble, biopersistent dusts (GBS) at workplaces. (Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie (Annual Meeting) <81, 2015, Kiel>)
Naunyn-Schmiedebergs archives of pharmacology, Vol.388 (2015), Supplement 1, pp.S69-S70, Abstract 276
Fraunhofer ITEM Creutzenberg (Publica)


Wibbertmann, Axel:
Mini-Sterilisator als Alternative
Medizin & Technik, (2015), No.3, pp.42-43
Fraunhofer ITEM Wibbertmann (Publica)


Yamaci, R.F.; Elsner, F.; Sziklavari, Z.; Potzger, T.; Hofmann, H.S.; Klein, C.:
Molecular characterization of early disseminating cancer cells in non-small cell lung cancer. (Metastasis Research Society (MRS International Biennial Congress) <15, 2014, Heidelberg>)
Clinical & experimental metastasis, Vol.32 (2015), No.3, pp.248
Fraunhofer ITEM


Hosseini, H.; Carolin, E.L.; Nanduri, L.K.; Werno, C.; Maneck, M.; Husemann, Y.; Klein, C.A.:
Molecular mechanisms of early cancer cell dissemination in breast cancer. (Metastasis Research Society (MRS International Biennial Congress) <15, 2014, Heidelberg>)
Clinical & experimental metastasis, Vol.32 (2015), No.3, pp.210
Fraunhofer ITEM


Urbanus, J.; Banton, M.; Carter, M.; Dudzina, T.; Geudens, B.; Jones, R.; Niemeck, G.; Pizzella, G.; Tibaldi, R.; Williams, S.; Rohde, A.; Ketelslegers, H.; Berger-Preiß, E.; Koch, W.; Schuchardt, S.:
Monitoring method for inhalation exposure to gas oil vapour and aerosol
Brussels: Concawe, 2015
(Concawe report Nr.8/2015)
urn:ISSN:0166-0810
Fraunhofer ITEM


Pedersen, Frauke; Holz, Olaf; Lauer, Gereon; Quintini, Gianluca; Kiwull-Schöne, Heidrun; Kirsten, Anne-Marie; Magnussen, Helgo; Rabe, Klaus F.; Goldmann, Torsten; Watz, Henrik:
Multi-analyte profiling of inflammatory mediators in COPD sputum - The effects of processing
Cytokine, Vol.71 (2015), No.2, pp.401-404
info:doi/10.1016/j.cyto.2014.10.008
Fraunhofer ITEM Holz (Publica)


Pedersen, Frauke; Marwitz, Sebastian; Holz, Olaf; Kirsten, Anne; Bahmer, Thomas; Waschki, Benjamin; Magnussen, Helgo; Rabe, Klaus F.; Goldmann, Torsten; Uddin, Mohib; Watz, Henrik:
Neutrophil extracellular trap formation and extracellular DNA in sputum of stable COPD patients
Respiratory Medicine, Vol.109 (2015), No.10, pp.1360-1362
info:doi/10.1016/j.rmed.2015.08.008
Fraunhofer ITEM Holz (Publica)


Kirkland, David; Brock, Tom; Haddouk, Hasnaà; Hargeaves, Victoria; Lloyd, Melvyn; Mc Garry, Sarah; Proudlock, Raymond; Sarlang, Séverine; Sewald, Katherina; Sire, Guillaume; Sokolowski, Andrea; Ziemann, Cristina:
New investigations into the genotoxicity of cobalt compounds and their impact on overall assessment of genotoxic risk
Regulatory toxicology and pharmacology, Vol.73 (2015), No.1, pp.311-338
urn:nbn:de:0011-n-3563739
info:doi/10.1016/j.yrtph.2015.07.016
Volltext
Fraunhofer ITEM Sewald (Publica)


Janssen, Ole; Hohlfeld, Jens M. (Betreuer); Braun, Armin (Referent); Dittrich, Anna-Maria (Korreferent) :
Niedrig dosierte inhalative Endotoxin Provokation bei gesunden Probanden als Modell in der klinischen Atemwegsforschung
Hannover, Medizinische Hochschule, Diss., 2015
Fraunhofer ITEM


Renne, Julius; Hinrichs, Jan; Schönfeld, Christian; Gutberlet, Marcel; Winkler, Carla; Faulenbach, Cornelia; Jakob, Peter; Schaumann, Frank; Krug, Norbert; Wacker, Frank; Hohlfeld, Jens M.; Vogel-Claussen, Jens:
Noninvasive quantification of airway inflammation following segmental allergen challenge with functional MR imaging: A proof of concept study
Radiology, Vol.274 (2015), No.1, pp.267–275
info:doi/10.1148/radiol.14132607
Fraunhofer ITEM Winkler (Publica)


Konzok, Sebastian; Schindler, Susann; Jonigk, Danny; Braubach, Peter; Braun, Armin; Sewald, Katherina:
A novel human organotypic tumor invasion model of cell line MDA-MB-231 in Precision-Cut Lung Slices (PCLS) to reduce animal experiments in preclinical oncology. (European Congress on Alternatives to Animal Testing <19, 2015, Linz>)
ALTEX Proceedings, Vol.4 (2015), No.2, pp.134
Fraunhofer ITEM


Schwarz, K.; Lueer, K.; Biller, H.; Windt, H.; Badorrek, P.; Hafner, D.; Koch, A.; Krug, N.; Koch, W.; Hohlfeld, J.:
A novel universal allergen challenge technique for efficacy testing of immunotherapy: Poster abstract. (International Society for Aerosols in Medicine (ISAM International Congress) <20, 2015, Munich>)
Journal of aerosol medicine and pulmonary drug delivery, Vol.28 (2015), No.3, pp.A-18
Fraunhofer ITEM


Gundert-Remy, Ursula; Batke, Monika; Bitsch, Annette; Gütlein, Martin; Kramer, Stefan; Partosch, Falko; Seeland, Madeleine:
Optimization of curation of the dataset with data on repeated dose toxicity. (European Societies of Toxicology (EUROTOX Congress) <51, 2015, Porto>)
Toxicology letters, Vol.238 (2015), No.2, Supplement, pp.S166
info:doi/10.1016/j.toxlet.2015.08.566
Fraunhofer ITEM


Schwotzer, Daniela; Hansen, Tanja; Niehof, Monika; Creutzenberg, Otto:
An overview of the InhalT-90 project - a 90-day inhalation toxicity study with CeO2 nanoparticles. (Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie (Annual Meeting) <81, 2015, Kiel>)
Naunyn-Schmiedebergs archives of pharmacology, Vol.388 (2015), Supplement 1, pp.S71, Abstract 283
Fraunhofer ITEM Schwotzer (Publica)


Jiménez Delgado, S.M.; Schindler, S.; Sewald, K.; Armin, B.:
Passively sensitized human organotypic tissue as asthma model to study mast cell-nerve interaction. (European Academy of Allergy and Clinical Immunology (Congress) <2015, Barcelona>)
Allergy. European journal of allergy and clinical immunology, Vol.70 (2015), Supplement S101, pp.219-220
Fraunhofer ITEM


Pohler, Petra; Müller, Meike; Winkler, Carla; Schaudien, Dirk; Sewald, Katherina; Müller, Thomas H.; Seltsam, Axel:
Pathogen reduction by ultraviolet C light effectively inactivates human white blood cells in platelet products
Transfusion, Vol.55 (2015), No.2, pp.337-347
info:doi/10.1111/trf.12836
Fraunhofer ITEM Müller (Publica)


Jiménez Delgado, Sharon Melissa; Schindler, Susann; Sewald, Katherina; Braun, Armin:
Peripheral sensory nerves stimulation lead to bronchoconstriction-augment in passive sensitized human precision-cut lung slices and Is histamine 1 receptor dependent. (American Thoracic Society (ATS International Conference) <2015, Denver/Colo.>)
American Journal of Respiratory and Critical Care Medicine, Vol.191 (2015), Art. A4107
Fraunhofer ITEM


Alberter, B.; Polzer, B.:
Personalisierte Tumortherapie: Isolierung und Charakterisierung zirkulierender Tumorzellen
GIT. Labor-Fachzeitschrift, (2015), No.8, 5 pp.
Fraunhofer ITEM


Lanfermann, Heinrich; Schindler, Chris; Jordan, Jens; Krug, Norbert; Raab, Peter:
Pharmacological MRI (phMRI) of the human central nervous system
Clinical neuroradiology, Vol.25 (2015), No.2, pp.259-266
info:doi/10.1007/s00062-015-0457-0
Fraunhofer ITEM Krug (Publica)


Haidl, P.; Pohlmann, G.; Cloes, R.M.:
Power requirement of pressurized metered-dose and dry powder inhalers (pMDIs AND DPIs). (International Society for Aerosols in Medicine (ISAM International Congress) <20, 2015, Munich>)
Journal of aerosol medicine and pulmonary drug delivery, Vol.28 (2015), No.3, pp.A22
Fraunhofer ITEM


Neuhaus, Vanessa; Danov, Olga; Witte, J.; Romberg, Susanne; Escher, Syliva; Braun, Armin; Sewald, Katherina:
Precision-cut lung slices as an alternative model for repeated-dose inhalation toxicity. (Society of Toxicology (Annual Meeting) <54, 2015, San Diego/Calif.>)
The Toxicologist, Vol.54 (2015), No.1, pp.338-339
Fraunhofer ITEM Neuhaus (Publica)


Czyz, Zbigniew Tadeusz; Kirsch, Stefan; Polzer, Bernhard:
Principles of whole-genome amplification
Kroneis, Thomas (Ed.): Whole genome amplification: Methods and protocols. New York: Springer Science+Business Media, 2015. (Methods in molecular biology 1347), pp. 1-14
info:doi/10.1007/978-1-4939-2990-0_1
Fraunhofer ITEM Czyz (Publica)


Schmeinck, Sina; Bitsch, Annette; Genth, H.:
Refinement and enhancement of a database for dermal absorption data. (Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie (Annual Meeting) <81, 2015, Kiel>)
Naunyn-Schmiedebergs archives of pharmacology, Vol.388 (2015), Supplement 1, pp.S90, Abstract 361
Fraunhofer ITEM Schmeinck (Publica)


Danov, Olga; Schröder, Katrin; Braubach, Peter; Jonigk, D.; Warnecke, G.; Braun, Armin; Escher, Syliva; Sewald, Katherina:
Risk assessment of inhalable read-across chemicals with different mode of action showed great differences in cytotoxicity in rat and human precision-cut lung slices. (Society of Toxicology (Annual Meeting) <54, 2015, San Diego/Calif.>)
The Toxicologist, Vol.54 (2015), No.1, pp.400, Abstract PS 1868
Fraunhofer ITEM Danov (Publica)


Homburg, Ursula; Renz, Harald; Timmer, Wolfgang; Hohlfeld, Jens M.; Seitz, Friedeborg; Lüer, Katrin; Mayer, Alexandra; Wacker, Anja; Schmidt, Oliver; Kuhlmann, Jens; Turowska, Agnieszka; Roller, Julia; Kutz, Klaus; Schlüter, Gerhard; Krug, Norbert; Garn, Holger:
Safety and tolerability of a novel inhaled GATA3 mRNA targeting DNAzyme in patients with TH2-driven asthma: Letter to the Editor
The journal of allergy and clinical immunology : JACI, Vol.136 (2015), No.3, pp.797-800
info:doi/10.1016/j.jaci.2015.02.018
Fraunhofer ITEM Hohlfeld (Publica)


Walter, Dorothee; Fischer, Monika; Steinberg, Pablo; Dasenbrock, Clemens:
A saline lavage model in the isolated perfused rat lung. (Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie (Annual Meeting) <81, 2015, Kiel>)
Naunyn-Schmiedebergs archives of pharmacology, Vol.388 (2015), Supplement 1, pp.S85, Abstract 342
Fraunhofer ITEM Walter (Publica)


Escrig, A.; Ibanez, M.J.; Monfort, E.; Bonvicini, G.; Salomoni, A.; Creutzenberg, O.; Ziemann, C.:
Selection of additives for reducing the toxicity of quartz in ceramic compositions
Ceramic forum international : CFI. Berichte der Deutschen Keramischen Gesellschaft, (2015), No.1-2, pp.63-69
Fraunhofer ITEM


Hahn, A.; Fischer, M.; Walter, D.; Dasenbrock, C.; Koch, W.; Begemann, K.; Greiner, M.:
Serious magic-nano-like lung oedemas caused by a liquid stain protection product: Using two new tests as a combined screening tool for aerosol products. (European Association of Poisons Centres and Clinical Toxicologists (EAPCCT International Congress) <35, 2015, Malta>)
Clinical toxicology, Vol.53 (2015), No.4, pp.318
Fraunhofer ITEM


Holst, Katrin; Guseva, Daria; Schindler, Susann; Sixt, Michael; Braun, Armin; Chopra, Himpriya; Pabst, Oliver; Ponimaskin, Evgeni:
The serotonin receptor 5-HT7R regulates the morphology and migratory properties of dendritic cells
Journal of cell science, Vol.128 (2015), No.15, pp.2866-2880
info:doi/10.1242/jcs.167999
Fraunhofer ITEM


Ziemann, Christina; Rahmer, Hartmut; Escrig Vidal, A.; Bonvicini, Giuliana; Ibanez Garcia, M.J.; Monfort Gimeno, E.; Creutzenberg, Otto H.:
The SILICOAT project: Approaches for an effective quartz surface coating in the traditional ceramics industry to increase workers' safety. Toxicological investigations. (Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie (Annual Meeting) <81, 2015, Kiel>)
Naunyn-Schmiedebergs archives of pharmacology, Vol.388 (2015), Supplement 1, pp.S66
Fraunhofer ITEM


Creutzenberg, Otto H.; Reamon-Buettner, Stella Marie; Tillmann, Thomas; Hansen, Tanja; Garcia, M.J.; Monfort, Eliseo; Bonvicini, Giuliana; Escrig, Alberto; Ziemann, Christina:
The Silicoat project: In vitro and in vivo toxicity screening of quartz varieties from ceramics industry and approaches for an effective quartz surface coating. (Society of Toxicology (Annual Meeting) <54, 2015, San Diego/Calif.>)
The Toxicologist, Vol.54 (2015), No.1, pp.295, Abstract PS 1379
Fraunhofer ITEM Creutzenberg (Publica)


Reamon-Buettner, Stella Marie; Hiemisch, Andreas; Lewin, Geertje; Dasenbrock, Clemens; Halter, Roman:
Single-promoter analysis of CpG and non-CpG methylation patterns in spleen of mice exposed to extremely low frequency magnetic field (ELF-MF). (Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie (Annual Meeting) <81, 2015, Kiel>)
Naunyn-Schmiedebergs archives of pharmacology, Vol.388 (2015), Supplement 1, pp.S56
Fraunhofer ITEM


Danov, Olga; Escher, Sylvia E.; Schröder, Katrin; Vorgrimmler, David; Bersch, Claus; Braubach, Peter; Jonigk, Danny; Pfennig, Olaf; Warnecke, Gregor; Braun, Armin; Sewald, Katherina:
Species comparison of rat and human precision-cut lung slices as an alternative in risk assessment based on read-across approach. (European Societies of Toxicology (EUROTOX Congress) <51, 2015, Porto>)
Toxicology letters, Vol.238 (2015), No.2, Supplement, pp.S332, Abstract P14-034
info:doi/10.1016/j.toxlet.2015.08.947
Fraunhofer ITEM


McInnes, Elizabeth F.; Ernst, Heinrich; Germann, Paul-Georg:
Spontaneous nonneoplastic lesions in control syrian hamsters in three 24-month long-term carcinogenicity studies
Toxicologic Pathology, Vol.43 (2015), No.2, pp.272-281
info:doi/10.1177/0192623314532569
Fraunhofer ITEM Ernst (Publica)


Knippenberg, Sarah; Ueberberg, Bianca; Maus, Regina; Bohling, Jennifer; Ding, Nadine; Tort Tarres, Meritxell; Hoymann, Heinz-G.; Jonigk, Danny; Izykowski, Nicole; Paton, James C.; Ogunniyi, Abiodun D.; Lindig, Sandro; Bauer, Michael; Welte, Tobias; Seeger, Werner; Guenther, Andreas; Sisson, H. Thomas; Gauldie, Jack; Kolb, Martin; Maus, Ulrich A.:
Streptococcus pneumoniae triggers progression of pulmonary fibrosis through pneumolysin
Thorax, Vol.70 (2015), No.7, pp.636-646
info:doi/10.1136/thoraxjnl-2014-206420
Fraunhofer ITEM


Knippenberg, Sarah; Ueberberg, Bianca; Maus, Regina; Bohling, Jennifer; Ding, Nadine; Tort Tarres, Meritxell; Hoymann, Heinz-G.; Jonigk, Danny; Izykowski, Nicole; Paton, James C.; Ogunniyi, Abiodun D.; Lindig, Sandro; Bauer, Michael; Welte, Tobias; Seeger, Werner; Guenther, Andreas; Sisson, H. Thomas; Gauldie, Jack; Kolb, Martin; Maus, Ulrich A.:
Streptococcus pneumoniae triggers progression of pulmonary fibrosis through pneumolysin. (American Thoracic Society (ATS International Conference) <2015, Denver/Colo.>)
American Journal of Respiratory and Critical Care Medicine, Vol.191 (2015), Art. A3920
Fraunhofer ITEM


Lewin, Geertje; Escher, Sylvia E.; Burg, Bart van der; Simetska, Nelly; Mangelsdorf, Inge:
Structural features of endocrine active chemicals - a comparison of in vivo and in vitro data
Reproductive toxicology, Vol.55 (2015), pp.81-94
info:doi/10.1016/j.reprotox.2014.10.009
Fraunhofer ITEM Lewin (Publica)


Escher, Sylvia; Batke, Monika; Arning, Jürgen; Brandt, Marc; Kupper, Jürgen; Eifert, Harald; Wibbertmann, Axel:
Support for the use of computer-based predictions like quantitative structure-activity relationships (QSAR methods) to avoid animal testing under REACH. (Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie (Annual Meeting) <81, 2015, Kiel>)
Naunyn-Schmiedebergs archives of pharmacology, Vol.388 (2015), Supplement 1, pp.S90, Abstract 363
info:doi/10.1007/s00210-015-1087-4
Fraunhofer ITEM Escher (Publica)


Guzvic, M.; Braun, B.; Ganzer, R.; Burger, M.; Nerlich, M.; Winkler, S.; Werner-Klein, M.; Czyz, Z.T.; Polzer, B.; Klein, C.A.:
Targeted expression profiling of single disseminated cancer cells isolated from bone marrow of prostate cancer patients. (Metastasis Research Society (MRS International Biennial Congress) <15, 2014, Heidelberg>)
Clinical & experimental metastasis, Vol.32 (2015), No.3, pp.204
Fraunhofer ITEM


Hohlfeld, Jens M.; Calverley, P.; Könen-Bergmann, M.; Metzdorf, N.; Bell, S.:
Tiotropium respimat: Comparison of bronchodilator efficacy of 5 and 2.5 µg doses. (Deutsche Gesellschaft für Pneumologie und Beatmungsmedizin (Kongress) <56, 2015, Berlin>)
Pneumologie, Vol.69 (2015), No.S01, Abstract P127
info:doi/10.1055/s-0035-1544635
Fraunhofer ITEM


Sewald, Katherina:
Translational models for acute respiratory injury and inflammation using precision cut lung slices. (Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie (Annual Meeting) <81, 2015, Kiel>)
Naunyn-Schmiedebergs archives of pharmacology, Vol.388 (2015), Supplement 1, pp.S84-S85, Abstract 340
Fraunhofer ITEM


Haider, Georg; Lee, Jae Hwa; Wiegand, Silke; Spies, Emma; Hoymann, Heinz-Gerd; Kummer, Wolfgang; Braun, Armin; Nassenstein, Christina:
TRPA1 agonists modulate the trachealis muscle tone via two independent mechanisms. (International Symposium "Frontiers in Chronic and Malignant Airways Disease" <4, 2015, Heidelberg>)
Pneumologie, Vol.69 (2015), No.7, pp.422, Abstract 31
info:doi/10.1055/s-0035-1556623
Fraunhofer ITEM Spies (Publica)


Haider, G.; Lee, J.-H.; Wiegand, S.; Spies, E.; Hoymann, H.-G.; Kummer, W.; Braun, A.; Nassenstein, C.:
TRPA1-Agonists: Novel bronchodilators?
Autonomic Neuroscience, Vol.192 (2015), pp.49-50
info:doi/10.1016/j.autneu.2015.07.406
Fraunhofer ITEM


Escher, Sylvia E.:
TTC concept: Non-oral routes and influence of local effects. (European Societies of Toxicology (EUROTOX Congress) <51, 2015, Porto>)
Toxicology letters, Vol.238 (2015), No.2, Supplement, pp.S7, Abstract CEC3-6
info:doi/10.1016/j.toxlet.2015.08.041
Fraunhofer ITEM


Escher, Sylvia E.; Hoffmann-Doerr, Simone; Pastor, Manuel; Partosch, Falko; Schröder, Katrin; Mangelsdorf, Inge:
Update of time extrapolation factors for risk assessment: The benefit of combined databases and probabilistic analyses. (European Societies of Toxicology (EUROTOX Congress) <51, 2015, Porto>)
Toxicology letters, Vol.238 (2015), No.2, Supplement, pp.S100, Abstract P03-042
info:doi/10.1016/j.toxlet.2015.08.332
Fraunhofer ITEM


Stöber, Werner; Steger-Hartmann, Thomas; Myatt, Glenn J.; Richarz, Andrea; Hengstler, Jan; Escher, Sylvia E.:
The use of AOPs in risk assessment: Development of biomarker based on a read across use case on VPA analogues in the Detective project. (European Societies of Toxicology (EUROTOX Congress) <51, 2015, Porto>)
Toxicology letters, Vol.238 (2015), No.2, Supplement, pp.S56-S57, Abstract P01-005
info:doi/10.1016/j.toxlet.2015.08.206
Fraunhofer ITEM


Sewald, Katherina:
Use of ex vivo organotypic lung tissue in translational research of respiratory injury and inflammation diseases. (European Congress on Alternatives to Animal Testing <19, 2015, Linz>)
ALTEX Proceedings, Vol.4 (2015), No.2, pp.212
Fraunhofer ITEM


Stöber, Regina; Escher, Sylvia E.; Hengstler, Jan G.:
VPA Read across: Development of predictive biomarkers by using toxicity data of structurally similar compounds. (European Congress on Alternatives to Animal Testing <19, 2015, Linz>)
ALTEX Proceedings, Vol.4 (2015), No.2, pp.220
Fraunhofer ITEM