Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2012Acute cigarette smoke exposure induces cytotoxicity and inflammation in living tissue of precision-cut lung slices
Lauenstein, Lan; Switalla, Simone; Ritter, Detlef; Knebel, Jan; Dasenbrock, Clemens; Braun, Armin; Sewald, Katherina
Abstract
2012Acute ozone induced airway inflammation does not effect resting human sympathetic nerve traffic
Tank, J.; Biller, Heike; Heusser, K.; Holz, Olaf; Diedrich, A.; Framke, T.; Koch, A.; Grosshennig, A.; Koch, Wolfgang; Krug, Norbert; Jordan, J.; Hohlfeld, Jens
Journal Article, Conference Paper
2012Allergic airway inflammation in mice deficient for the antigen-processing protease cathepsin E
Pilzner, C.; Bühling, F.; Reinheckel, T.; Chwieralski, C.; Rathinasamy, A.; Lauenstein, H.-D.; Wex, T.; Welte, T.; Braun, A.; Groneberg, D.A.
Journal Article
2012Alternative activation of macrophages during the allergic airway inflammation alters antigen presenting capacities
Winkler, Carla; Carstens, Hauke; Müller, Meike; Schaumann, Frank; Faulenbach, Cornelia; Hohlfeld, Jens M.
Abstract
2012Anforderungsanalyse und Auswahl einer Software zur Intranetpräsentation eines Leitfadendokuments
Kleine, Maren
: Bott, Oliver (Erstprüfer); Heina, Martina (Zweitprüfer)
Bachelor Thesis
2012Assessment of lung toxicity induced by chemical allergens in human precision-cut lung slices
Lauenstein, Lan; Switalla, Simone; Prenzler, Frauke; Pfennig, Olaf; Förster, Christine; Braun, Armin; Sewald, Katherina
Abstract
2012Attenuation of inhibitory prostaglandin E2 signaling in human lung fibroblasts is mediated by phosphodiesterase 4
Michalski, Joel; Kanaji, Nobuhiro; Liu, Xiangde; Nogel, Steve; Wang, Xingqui; Basma, Hesham; Nakanishi, Masanori; Sato, Tadasi; Gunji, Yoko; Fahrid, Maha; Nelson, Amy; Muller, Kai-Christian; Holz, Olaf; Magnussen, Helgo; Rabe, Klaus F.; Toews, Myron L.; Rennard, Stephen I.
Journal Article
2012Bacillus Anthracis lethal toxin impairs alveolar epithelial barrier function
Langer, M.; Booth, J.; Duggan, E.S.; Patel, V.I.; Awasthi, S.; Metcalf, J.; Veres, T.Z.; Prenzler, F.; Sewald, K.; Braun, A.; Lupu, F.; Coggeshall, K.
Conference Paper, Journal Article
2012Bacillus anthracis lethal toxin reduces human alveolar epithelial barrier function
Langer, Marybeth; Duggan, Elizabeth S.; Booth, John L.; Patel, Vineet I.; Zander, Ryan A.; Silasi-Mansat, Robert; Ramani, Vijay; Veres, Tibor Z.; Prenzler, Frauke; Sewald, Katherina; Williams, Daniel M.; Coggeshall, Kenneth M.; Awasthi, Shanjana; Lupu, Florea; Burian, Dennis; Ballard, Jimmy D.; Braun, Armin; Metcalf, Jordan P.
Journal Article
2012Bacterial infection triggers exacerbation of established pulmonary fibrosis in mice: Impact on lung protective immunity
Ueberberg, Bianca; Janze, Ann-Kathrin; Steinwede, Kathrin; Maus, Regina; Magel, Lavinia; Hoymann, Heinz-Gerd; Braun, Armin; Langer, Florian; Jonigk, Danny; Kolb, Martin; Gauldie, Jack; Welte, Tobias; Maus, Ulrich A.
Abstract
2012Die Bedeutung von Pollen und Starch Granules bei der Allergie der Atemwege
Emmert, Lorenz Samy
: Krug, Norbert (Doktorvater)
Dissertation
2012Biological interactions and toxicity of nanomaterials in the respiratory tract and various approaches of aerosol generation for toxicity testing
Creutzenberg, O.
Journal Article
2012Break-up testing of waste-form materials
Metcalfe, M.P.; Koch, Wolfgang; Turner, G.
Journal Article
2012Cathepsin G and neutrophil elastase contribute to lung protective immunity against mycobacterial infections in mice
Steinwede, Kathrin; Maus, Regina; Bohling, Jennifer; Voedisch, Sabrina; Braun, Armin; Ochs, Matthias; Schmiedl, Andreas; Walter, Kerstin; Bange, Franz; Welte, Tobias; Ehlers, Stefan; Maus, Ulrich A.
Abstract
2012Cathepsin G and neutrophil elastase contribute to lung-protective immunity against mycobacterial infections in mice
Steinwede, Kathrin; Maus, Regina; Bohling, Jennifer; Voedisch, Sabrina; Braun, Armin; Ochs, Matthias; Schmiedl, Andreas; Länger, Florian; Gauthier, Francis; Roes, Jürgen; Welte, Tobias; Bange, Franz C.; Niederweis, Michael; Bühling, Frank; Maus, Ulrich A.
Journal Article
2012Change in agglomeration status and toxicokinetic fate of various nanoparticles in vivo following lung exposure in rats
Creutzenberg, O.; Bellmann, B.; Korolewitz, R.; Koch, W.; Mangelsdorf, I.; Tillmann, T.; Schaudien, D.
Journal Article
2012Characterization of exhaled particles from the human lung in airway obstruction
Biller, Heike; Schwarz, Katharina; Windt, Horst; Koch, Wolfgang; Hohlfeld, Jens M.
Abstract
2012Chlamydia pneumoniae and asthma bronchiale in a mouse model: Decrease in airway hyperresponsiveness to house dust mite allergen after pneumonia
Dutow, P.; Lingner, S.; Bode, J.; Laudeley, R.; Glage, S.; Hoymann, H.G.; Dittrich, A.M.; Muller, M.; Braun, A.; Klos, A.
Conference Paper, Journal Article
2012Combined micro-PET/micro-CT imaging of lung tumours in SPC-raf and SPC-myc transgenic mice
Rodt, T.; Luepke, M.; Boehm, C.; Hueper, K.; Halter, R.; Glage, S.; Hoy, L.; Wacker, F.; Borlak, J.; Falck, C. von
Journal Article
2012Comparison of methods to derive health-based guidance or limit values for chemicals
Licht, Oliver; Voss, Jens Uwe; Mangelsdorf, Inge
Journal Article, Conference Paper
2012Comparison of timothy grass pollen extract- and single major allergen-induced gene expression and mediator release in airway epithelial cells
Röschmann, K.I.L.; Kuijen, A.-M. van; Luiten, S.; Jonker, M.J.; Breit, T.M.; Fokkens, W.J.; Petersen, A.; Drunen, C.M. van
Journal Article
2012CRTH2 antagonist, BI 671800 (BI), reduces nasal symptoms and inhibits nasal cytokines and eosinophils in SAR patients exposed to grass pollen in an environmental challenge chamber (ECC)
Krug, Norbert; Gupta, A.; Badorrek, Philipp; Müller, Meike; Casper, Anja; Pivovarova, A.; Hilbert, J.; Koenen, R.; Hohlfeld, Jens M.; Wood, C.
Abstract
2012Cytoprotective effect of the small GTPase RhoB expressed upon Ras glucosylation by Clostridium sordellii Lethal Toxin
May, Martin; Huelsenbeck, J.; Schulz, Florian; Fritz, G.; Genth, H.
Journal Article, Conference Paper
2012Depletion of neutrophils from induced sputum using a novel bead and sieve-separation system
Holz, Olaf; Schaumann, Frank; Janben, Ole; Lavae-Mokhtari, Bianca; Witte, Lena; Krug, Norbert; Heinrich, J. M.; Hohlfeld, Jens M.
Abstract
2012Derived values and databases for non-cancer endpoints: Considerations and concerns
Tluczkiewicz, Inga; Batke, Monika; Mangelsdorf, Inge; Escher, Sylvia
Journal Article, Conference Paper
2012Detection of air trapping in chronic obstructive pulmonary disease by low frequency ultrasound
Morenz, Katrin; Biller, Heike; Wolfram, Frank; Leonhardt, Steffen; Ruter, Dirk; Glaab, Thomas; Uhlig, Stefan; Hohlfeld, Jens M.
Journal Article
2012Dissecting epigenetic silencing complexity in the mouse lung cancer suppressor gene cadm1
Reamon-Büttner, Stella Marie; Borlak, Jürgen
Journal Article
2012Effect of Tiotropium on in vivo and ex vivo lung function in a rat model of bronchoconstriction
Seehase, Sophie; Köhncke, Sarah-Philine; Hoymann, Heinz-Gerd; Braun, Armin; Sewald, Katherina
Abstract
2012Effekte der Partikeltranslokation von feinen und nanoskaligen Titandioxid-Partikeln nach Inhalation und intranasaler Instillation bei der Ratte
Lehmbecker, Annika
: Baumgärtner, Wolfgang (1. Gutachter); Claus, Peter (2. Gutachter); Gernert, Manuela (3. Gutachter); Harleman, Johannes H. (4. Gutachter)
Dissertation
2012Estimation of the consumer inhalation risk of waterproofing sprays
Fischer, Monika; Koch, Wolfgang; Windt, Horst; Dasenbrock, Clemens
Journal Article, Conference Paper
2012Etablierung pathway-spezifischer Genexpressionsanalysen am Beispiel der Wirkung von Paraquat auf humane Lungenepithelzellen
Augustin, Christian
: Pfitzner, Reinhard (Erstprüfer); Niehof, Monika (Zweitprüfer)
Bachelor Thesis
2012The EvA study: Aims and strategy
Ziegler-Heitbrock, L.; Frankenberger, M.; Heimbeck, I.; Burggraf, D.; Wjst, M.; Häussinger, K.; Brightling, C.; Gupta, S.; Parr, D.; Subramanian, D.; Singh, D.; Kolsum, U.; Boschetto, P.; Potena, A.; Gorecka, D.; Nowinski, A.; Barta, I.; Döme, B.; Strausz, J.; Greulich, T.; Vogelmeier, C.; Bals, R.; Hohlfeld, J.M.; Welte, T.; Venge, P.; Gut, I.; Boland, A.; Olaso, R.; Hager, J.; Hiemstra, P.; Rabe, K.F.; Unmüßig, M.; Müller-Quernheim, J.; Prasse, A.
Journal Article
2012Ex vivo lung culture models of marmoset monkeys and humans for anti-inflammatory drug testing
Seehase, Sophie; Neuhaus, Vanessa; Kaup, Franz-Josef; Pfennig, O.; Förster, Christine; Hohlfeld, Jens Michael; Knauf, Sascha; Braun, Armin; Sewald, Katherina
Abstract
2012Experience with an allergen challenge chamber for clinical trials in allergic rhinitis
Krug, Norbert; Badorrek, Phillipp; Hohlfeld, Jens Michael
Journal Article, Conference Paper
2012Food for thought... A toxicology ontology roadmap
Hardy, B.; Apic, G.; Carthew, P.; Clark, D.; Cook, D.; Dix, I.; Escher, S.; Hastings, J.; Heard, D.J.; Jeliazkova, N.; Judson, P.; Matis-Mitchell, S.; Mitic, D.; Myatt, G.; Shah, I.; Spjuth, O.; Tcheremenskaia, O.; Toldo, L.; Watson, D.; White, A.; Yang, C.
Journal Article
2012Fraunhofer-Institut für Toxikologie und Experimentelle Medizin. Leistungen und Ergebnisse. Jahresbericht 2011
: Nastevska, Cathrin (Red.); Schlemminger, Karin (Übers.)
Annual Report
2012Generation of ips-like cells from COPD lung fibroblasts
Basma, Hesham; Gunji, Yoko; Liu, Xiangde; Nelson, Amy; Farid, Maha; Iwasawa, Shunichiro; Ikari, Jun; Wang, Xingqui; Holz, Olaf; Müller, Kai-Christian; Magnussen, Helgo; Rabe, Klaus; Rennard, Stephen I.
Abstract
2012Human alveolar epithelial barrier function is impaired by bacillus anthracis lethal toxin
Langer, Marybeth; Booth, John L.; Patel, Vineet I.; Duggan, Elizabeth S.; Braun, Armin; Ramani, Vijay; Awasthi, Shanjana; Silasi-Mansat, Robert; Lupu, Florea; Coggeshall, Kenneth M.; Metcalf, Jordan P.
Abstract
2012Human pleural mesothelial MeT-5A cells are a limited in vitro model system in determining potential asbestos-like effects of multiwall carbon nanotubes
Ziemann, Christina; Reamon-Büttner, Stella-Marie; Schlichting, Anja; Brockmeyer, Heidrun; Rahmer, Hartmut; Bellmann, Bernd
Journal Article, Conference Paper
2012Immunotoxic characterization of a nanoparticle-based inhalable influenza vaccine in murine and human precision cut lung slices
Neuhaus, Vanessa; Schwarz, Katharina; Koch, Wolfgang; Sewald, Katherina; Yusibov, V.; Braun, Armin
Abstract
2012Impacts after inhalation of nano- and fine-sized titanium dioxide particles: morphological changes, translocation within the rat lung, and evaluation of particle deposition using the relative deposition index
Eydner, M.; Schaudien, D.; Creutzenberg, O.; Ernst, H.; Hansen, T.; Baumgärtner, W.; Rittinghausen, S.
Journal Article
2012In vitro study revealed different size behavior of different nanoparticles
Schaudien, D.; Knebel, J.; Creutzenberg, O.
Journal Article
2012Inactivation of human white blood cells in platelet concentrates after pathogen reduction by UVC-light in the theraflex UV-platelets system
Seltsam, A.; Pohler, P.; Mueller, M.; Winkler, C.; Muller, T.H.
Conference Paper, Journal Article
2012Influence of extremely low frequency magnetic fields on juvenile development and behaviour in a mouse model
Lewin, Geertje; Buschmann, Jochen; Asmuss, Monika
Journal Article, Conference Paper
2012International harmonization of toxicologic pathology nomenclature
Mann, P.C.; Vahle, J.; Keenan, C.M.; Baker, J.F.; Bradley, A.E.; Goodman, D.G.; Harada, T.; Herbert, R.; Kaufmann, W.; Kellner, R.; Nolte, T.; Rittinghausen, S.; Tanaka, T.
Journal Article
2012International round-robin study on the Ames fluctuation test
Reifferscheid, Georg; Maes, Hanna; Allner, Bernhard; Badurova, Jana; Belkin, Shimshon; Bluhm, Kerstin; Brauer, Frank; Bressling, Jana; Domeneghetti, Stefania; Elad, Tal; Flückiger-Isler, Sini; Grummt, Hans-Juergen; Gürtler, Rainer; Hecht, Adiel; Heringa, Minne; Hollert, Henner; Huber, Stefanie; Kramer, Maike; Ratte, Toni; Sauerborn-Klobucar, Roberta; Magdeburg, Axel; Sokolowski, Andrea; Soldan, Premysl; Smital, Tvrtko; Stalter, Daniel; Venier, Paola; Ziemann, Christina; Zipperle, Jürgen; Buchinger, Sebastian
Journal Article
2012Kinetics and mechanism of the reaction of OH with the trimethylbenzenes - experimental evidence for the formation of adduct isomers
Bohn, B.; Zetzsch, C.
Journal Article
2012Lack of detectable diffuse or neuritic plaques and neurofibrillary tangles in the brains of aged hamsters
Gerhauser, Ingo; Wohlsein, Peter; Ernst, Heinrich; Germann, Paul-Georg; Baumgärtner, Wolfgang
Journal Article
2012Leichtbau in Mobilität und Fertigung
: Rommel, Steve (Red.); Geiger, Raphael (Red.); Schneider, Ralph (Red.); Baumann, Michael (Red.); Brandstetter, Peter (Red.); Held, Michael (Red.); Albrecht, Stefan (Red.); Creutzenberg, Otto (Red.); Dasenbrock, Clemens (Red.)
Study
2012Low-dose endotoxin inhalation in healthy volunteers: A challenge model for early clinical drug development of novel anti-inflammatory compounds
Schaumann, Frank; Holz, Olaf; Janben, Ole; Lavae-Mokhtari, Bianca; Witte, Lena; Biller, Heike; Krug, Norbert; Hohlfeld, Jens M.
Abstract
2012LPS-induced lung inflammation in marmoset monkeys - an acute model for anti-inflammatory drug testing
Seehase, S.; Lauenstein, H.D.; Schlumbohm, C.; Switalla, S.; Neuhaus, V.; Förster, C.; Fieguth, H.G.; Pfennig, O.; Fuchs, E.; Kaup, F.J.; Bleyer, M.; Hohlfeld, J.M.; Braun, A.; Sewald, K.; Knauf, S.
Journal Article
2012Lung function measurements in rodents in safety pharmacology studies
Hoymann, Heinz Gerd
Journal Article
2012Lung tumour growth kinetics in SPC-c-Raf-1-BB transgenic mice assessed by longitudinal in-vivo micro-CT quantification
Rodt, Thomas; Falck, Christian von; Dettmer, Sabine; Hueper, Katja; Halter, Roman; Hoy, Ludwig; Luepke, Matthias; Borlak, Jürgen; Wacker, Frank
Journal Article
2012Marmoset monkeys as a preclinical model in respiratory research
Seehase, Sophie
: Kaup, Franz-Josef (1. Gutachter); Zimmermann, Elke (2. Gutachterin); Braun, Armin (Wiss. Betreuung)
Dissertation
2012Measurement of diameter of different nanoparticle agglomerates after contact with A549 cells revealed different size behavior
Schaudien, Dirk; Knebel, Jan; Rittinghausen, Susanne; Creutzberg, Otto
Journal Article, Conference Paper
2012MicroScout - an assistance system for histological analysis in forensics
Jahn, U. von; Ernst, Heinrich; Matthies, H.K.; Albrecht, U.V.
Conference Paper, Journal Article
2012MYC-regulated genes involved in liver cell dysplasia identified in a transgenic model of liver cancer
Hunecke, D.; Spanel, R.; Langer, F.; Nam, S.W.; Borlak, J.
Journal Article
2012Nasal passages of Göttingen minipigs from the neonatal period to young adult
Kuper, C.F.; Ernst, H.; Oostrum, L.C.M. van; Rittinghausen, S.; Penninks, A.H.; Ganderup, N.-C.; Wolterbeek, A.P.M.
Journal Article
2012Nephrotoxicity of organic solvents from skin exposure
Mangelsdorf, Inge; Voss, Jens Uwe
Book Article
2012Neurally mediated airway constriction in human and other species
Schlepütz, M.; Rieg, A.D.; Seehase, S.; Spillner, J.; Perez-Bouza, A.; Braunschweig, T.; Schroeder, T.; Bernau, M.; Lambermont, V.; Schlumbohm, C.; Sewald, K.; Autschbach, R.; Braun, A.; Kramer, B.W.; Uhlig, S.; Martin, C.
Journal Article
2012Neuro-immune interaction in allergic airway inflammation: Expression and function of dendritic cells in sensory airway ganglia neurons
Le, Dung D.; Rochlitzer, Sabine; Funck, Ulrke; Suhling, Hendrik; Braun, Armin; Welte, Tobias; Din, Quoc Thai
Abstract
2012Neuropeptides control the dynamic behavior of airway mucosal dendritic cells
Voedisch, S.; Rochlitzer, S.; Veres, T.Z.; Spies, E.; Braun, A.
Journal Article
2012Neuropeptides influence airway dendritic cell behavior
Braun, Armin; Spies, Emma; Rochlitzer, Sabine; Voedisch, Sabrina
Abstract
2012A new analytical approach for the comprehensive characterization of polar xenobiotic organic compounds downgradient of old municipal solid waste (MSW) landfills
Preiß, A.; Berger-Preiß, E.; Elend, M.; Gerling, S.; Kühn, S.; Schuchardt, S.
Journal Article
2012A new model for testing human specific anti-inflammatory drugs: LPS-induced lung inflammation in the common marmoset
Knauf, Sascha; Seehase, Sophie; Switalla, Simone; Neuhaus, Vanessa; Zöller, Martina; Kaup, Franz-Josef; Schlumbohm, Christina; Fuchs, Eberhard; Lauenstein, Hand D.; Sewald, Katherina; Hohlfeld, Jens Michael; Braun, Armin
Abstract
2012The non-intubated, spontaneously breathing, continuous positive airway pressure (CPAP) ventilated pre-term lamb: A unique animal model
Rahmel, D.K.; Pohlmann, G.; Iwatschenko, P.; Volland, J.; Liebisch, S.; Kock, H.; Mecklenburg, L.; Maurer, C.; Kemkowski, J.; Taut, F.J.H.
Journal Article, Conference Paper
2012OpenTox predictive toxicology framework
Tcheremenskaia, Olga; Benigni, Romualdo; Nikolova, Ivelina; Jeliazkova, Nina; Escher, Sylvia E.; Batke, Monika; Baier, Thomas; Poroikov, Vladimir; Lagunin, Alexey; Rautenberg, Micha; Hardy, Barry
Journal Article
2012Optimierung der Auswertmethodik zur Quantifizierung von pathologischen Veränderungen durch Carbon Nanotubes
Weiß, Martin
: Kauer, Gerhard (Erstprüfer); Rittinghausen, Susanne (Zweitprüfer)
Bachelor Thesis
2012PET/CT imaging of c-Myc transgenic mice identifies the genotoxic N-Nitroso-Diethylamine as carcinogen in a Short-Term cancer bioassay
Hueper, K.; Elalfy, M.; Laenger, F.; Halter, R.; Rodt, T.; Galanski, M.; Borlak, J.
Journal Article
2012A pilot study on the refinement of acute inhalation toxicity studies
Fischer, M.; Koch, W.; Windt, H.; Dasenbrock, C.
Journal Article
2012Pollen starch granules in bronchial inflammation
Badorrek, Philipp; Dick, Melanie; Emmert, Lorenz; Schaumann, Frank; Koch, Wolfgang; Hecker, Hartmut; Murdoch, Robert; Hohlfeld, Jens M.; Krug, Norbert
Journal Article
2012Prostaglandin E2 stimulates the production of vascular endothelial growth factor through the E-prostanoid-2 receptor in cultured human lung fibroblasts
Nakanishi, Masanori; Sato, Tadashi; Li, Yingji; Nelson, Amy J.; Farid, Maha; Michalski, Joel; Kanaji, Nobuhiro; Wang, Xingqi; Basma, Hesham; Patil, Amol; Goraya, Jadvinder; Liu, Xiangde; Togo, Shinsaku; Toews, Myron L.; Holz, Olaf; Muller, Kai-Christian; Magnussen, Helgo; Rennard, Stephen I.
Journal Article
2012A reference aerosol generator based on Brownian coagulation in a continuously fed well stirred tank reactor
Koch, W.; Lödding, H.; Pohlmann, G.
Journal Article
2012Repeatability of and relationship between potential COPD biomarkers in bronchoalveolar lavage, bronchial biopsies, serum, and induced sputum
Röpcke, S.; Holz, O.; Lauer, G.; Müller, M.; Rittinghausen, S.; Ernst, P.; Lahu, G.; Elmlinger, M.; Krug, N.; Hohlfeld, J.M.
Journal Article
2012Reproducibility of serum biomarkers and relationship to airway inflammation following LPS challenge in healthy volunteers
Holz, Olaf; Tan, Lisa; Faulenbach, Cornelia; Müller, Meike; Krug, Norbert; McLeod, Alison; Hohlfeld, Jens M.
Abstract
2012The respiratory tract
Braun, Armin; Ernst, Heinrich; Schaudien, Dirk; Hoymann, Heinz-Gerd; Rittinghausen, Susanne
Book Article
2012Rhinovirus application on the background of allergic airway inflammation in a chronic house dust mite model
Rochlitzer, Sabine; Hoymann, Heinz-Gerd; Müller, Meike; Braun, Armin
Abstract
2012Safety and efficacy of house dust mite allergen challenge in patients with allergic rhinitis using a novel technique for inhalation studies in the Fraunhofer environmental challenge chamber
Lueer, Katrin; Biller, Heike; Windt, Horst; Müller, Meike; Badorrek, Philipp; Haefner, Dietrich; Framke, Theodor; Koch, Armin; Ziehr, Holger; Krug, Norbert; Koch, Wolfgang; Hohlfeld, Jens M.
Abstract
2012Scientific basis for the Soviet and Russian radiofrequency standards for the general public. Review
Repacholi, M.; Grigoriev, Y.; Buschmann, J.; Pioli, C.
Journal Article
2012Semi-quantitative assessment of localized pulmonary inflammation by magnetic resonance imaging in patients with mild allergic asthma following segmental allergen challenge
Vogel-Claussen, Jens; Schaumann, Frank; Renne, Julius; Hinrichs, Jan; Schoenfeld, Christian; Gutberlet, Marcel; Hüper, Klaudia; Winkler, Carla; Faulenbach, Cornelia; Krug, Norbert; Wacker, Frank; Hohlfeld, Jens M.
Abstract
2012Sequence error storms and the landscape of mutations in cancer
Kirsch, S.; Klein, C.A.
Journal Article
2012Single breath particle characterization to detect small airway alterations
Schwarz, Katharina; Hohlfeld, Jens M.; Biller, Heike; Koch, Wolfgang
Abstract
2012Spontaneously occurring multicentric basal cell carcinoma and keratoacanthomas in a multimammate mouse (Mastomys spp.)
Eydner, M.; Jacobsen, B.; Thomann, M.; Rittinghausen, S.; Fehr, M.; Baumgärtner, W.
Journal Article
2012Stable inflammatory phenotype in smokers and smokers with COPD
Holz, Olaf; Roepcke, Stefan; Lauer, Gereon; Krug, Norbert; Ernst, Peter; Lahu, Gezim; Hohlfeld, Jens M.
Abstract
2012Subacute and subchronic inhalation toxicity and dermal absorption of the nanoscaled zinc oxide Z-COTE HP1 in the rat
Creutzenberg, Otto H.; Ziemann, Christina; Hansen, Tanja; Ernst, Heinrich; Schaudien, Dirk; Schuchardt, Sven; Wiench, Karin; Bellmann, Bernd
Journal Article
2012Surfactant protein D modulates allergen particle uptake and inflammatory response in a human epithelial airway model
Schleh, Carsten; Rothen-Rutishauser, Barbara M.; Blank, Fabian; Lauenstein, Hans D.; Nassimi, Matthias; Krug, Norbert; Braun, Armin; Erpenbeck, Veit; Gehr, Peter; Hohlfeld, Jens M.
Journal Article
2012Suspension of MWCNT for toxicological in vivo and in vitro studies
Heinrich, Uwe; Schlichting, Anja; Ziemann, Christina; Seyock, S.; Haase, D.; Leonhardt, A.; Bellmann, Bernd
Journal Article
2012Synthesis of N-Dodecylethanamide-DTTA and characterization by mass spectrometry, NMR and IR spectroscopy
Kongtso, Adeline
: Butenschön, Holger (Erstprüfer); Schuchardt, Sven (Zweitprüfer)
Bachelor Thesis
2012Systemic biomarkers of neutrophilic inflammation, tissue injury and repair in COPD patients with differing levels of desease severity
Cockayne, Debra A.; Cheng, Donovan T.; Waschki, Benjamin; Sridhar, Sriram; Ravindran, Palanikumar; Hilton, Holly; Kourteva, Galina; Bitter, Hans; Pillai, Sreekumar G.; Visvanathan, Sudha; Müller, Kai-Christian; Holz, Olaf; Magnussen, Helgo; Watz, Henrik; Fine, Jay S.
Journal Article
2012Toxicology ontology perspectives
Hardy, B.; Apic, G.; Carthew, P.; Clark, D.; Cook, D.; Dix, I.; Escher, S.; Hastings, J.; Heard, D.J.; Jeliazkova, N.; Judson, P.; Matis-Mitchell, S.; Mitic, D.; Myatt, G.; Shah, I.; Spjuth, O.; Tcheremenskaia, O.; Toldo, L.; Watson, D.; White, A.; Yang, C.
Journal Article
2012Transient potential channel A1 and mast cell activation in bronchial hyperreactivity caused by hypochlorite and OVA in mice
Hox, V.; Vanoirbeek, J.; Alpizar, Y.A.; Voedisch, S.; Bobic, S.; Callebaut, I.; Vooght, V. de; Sharify, A.; Gerven, L. van; Ceuppens, Jan L.; Vries, A. de; Braun, A.; Hoet, P.; Talavera, K.; Nemery, B.; Hellings, P.
Journal Article, Conference Paper
2012Untersuchungen zur Entwicklung eines Kultivierungsmediums für eine humane Amniocyten-Zelllinie
Müller, Janina
: Lang, Siegmund (Referent); Ziehr, Holger (Koreferent)
Bachelor Thesis
2012Untersuchungen zur Verwendung verschiedener chromatographischer Methoden in der Herstellung und Analytik biopharmazeutischer Plasmide
Füller, Jendrik
: Rau, Udo (Erstgutachter); Ziehr, Holger (Zweitgutachter)
Master Thesis
2012Validation of an EDP assisted model for assessing inhalation exposure and dermal exposure during spraying processes
Koch, Wolfgang; Behnke, Wolfgang; Berger-Preiß, Edith; Kock, Heiko; Gerlin, Susanne; Hahn, Stefan; Schröder, Katrin
Report
2012Validierung funktioneller Untersuchungen im Rahmen von Developmental Neurotoxicity Studies entsprechend OECD 426 unter Nutzung einer geeigneten Positivsubstanz
Wehren, Teresa
: Dasenbrock, Clemens (1. Referent)
Master Thesis
2012Verfahren zur Analyse der Ausatemluft
Schwarz, Katharina; Koch, Wolfgang; Windt, Horst; Hohlfeld, Jens; Biller, Heike
Patent
2012Vergleich von Protein A- und Kationenaustauschchromatographie bei der Antikörperaufarbeitung aus Zellkulturüberständen
Geiszkopf, Andy
: Paulsen, Jens (Betreuer)
Bachelor Thesis
2012Vergleich zweier eukaryotischer Expressionssyteme in der Zelllinienentwicklung
Dietrich, Jana
: Biselli, Manfred (Erstprüfer); Veith, Nathalie (Zweitprüfer)
Bachelor Thesis
2012Vergleichende Untersuchungen zur Charakterisierung ultrafeiner Partikel in Rauchen beim Schweißen und bei verwandten Verfahren. Tl.1: Grundlagen der Untersuchung
Pohlmann, Gerhard; Holzinger, Karl; Spiegel-Ciobanu, Vilia E.
Journal Article
2012Vergleichende Untersuchungen zur Charakterisierung ultrafeiner Partikel in Rauchen beim Schweißen und bei verwandten Verfahren. Tl.2: Ergebnisse und Diskussion
Pohlmann, Gerhard; Holzinger, Karl; Spiegel-Ciobanu, Vilia E.
Journal Article
2012Zelllinienentwicklung und Etablierung einer High-Throughput-Methode zur Optimierung einer plattformbasierten Antikörperaufreinigung
Niermeier, Dennis
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