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1988
Conference Paper
Titel
Dialysis membrane reactors for enzymatic conversions in biotechnical processes - functional principles and examples for application.
Alternative
Dialyse-Membranreaktoren für enzymatische Umsetzungen bei biotechnischen Verfahren - Funktionsprinzipien und Anwendungsbeispiele
Abstract
With regard to the economy and technology of parocess engineering industrial biotechnology strives for continous operations. When using expensive but high efficient biocatalysts their immobilization is necessary to reach long using times of the enzymes. Different kinds of immobilization are known. The paper describes the immobilization by dialysis-hollow-fibre-membranes. In this case the substrate flow continuously through the tube-side of the capillary membranes of the membrane reactor and the cut-off of the membrane is choosen so that the enzyme is immobilized in the extracapillary volume of the reactor. The substrate diffuses through the membrane into the enzyme solution caused by the driving concentration difference which is always guaranteed by the enzymatically catalyzed reaction. The products diffuses back into the tube-side of the capillary membrane. So, a simple continuous process is realized by equally favourable relation between membrane area and reactor volume. Especially f or this process developed membrane reactors are presented. The important parameters are explained by results of the hydrolysis of lactose in different model solutions in lab and pilot plant scale.
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