Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.

Ultrastructural observations in mouse lungs after short term inhalation of cadmium compounds

: Dasenbrock, C.; Paulini, I.; Thiedemann, K.-U.

Collery, P.:
Metal ions in biology and medicine '90
London: Libbey, 1990
ISBN: 0-86196-243-5
International Symposium on Metal Ions in Biology and Medicine <1, 1990, Reims>
Fraunhofer ITA ( ITEM) ()
cadmium; Inhalation; light microscopy; lung; mouse; pathology; scanning electron microscopy; short-term inhalation; transmission electron microscopy

Chronic environmental or workplace inhalation exposure to Cadmiun (Cd) compounds causes lung cancer, but the effects of acute Cd inhalation are not known. In this study, the acute morphological changes due to short term Cd exposure in lung were investigated by light and transmission electron microscopy. Acute Cd inhalation causes severe lung damage in mice which partly persists after a clean air recovery period. Different Cd compounds evoke different types of morphological changes, Cd oxide causing the earliest and most severe tissue damage.