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PGE1 improves red blood cell velocity in capillaries of conscious rats -WKY and SHR- within a therapeutical range

: Creutzig, A.; Hertel, R.F.

International journal of microcirculation, Clinical and experimental 7 (1988), Nr.2, S.184
ISSN: 0167-6865
Gesellschaft für Mikrozirkulation (Jahrestagung) <11, 1987, Bern>
Fraunhofer ITA ( ITEM) ()
blood vessel; Blutgefäß; capillary vessel; experimental angiology; experimentelle Angiologie; Kapillargefäß; microcirculation; Mikrozirkulation; PGE1; Prostaglandin E1; rat; Ratte; SHR; spontaneously hypertensive rat; wistar kyoto; WKI

This study was conducted to investigate red blood cell velocity (very) and diameters of copillaries (0cap) of conscious rats after low-dosed intravenous prostaglandin e1 injections. PGE1 influences skin and muscle vasculature homogeneously, thus the depilated rat auricle was used as a model. From our finings we conclude that intravenously injected PGE1 improves blood flow in capillaries within a therapeutical range.