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Multianalyt sensor for the simultaneous determination of glucose, L-lactate and uric acid based on a microelectronic array

 

Puers, R. ; Catholic Univ., Leuven:
Eurosensors X. Proceedings
Leuven: Catholic University, 1996
ISBN: 90-803282-1-9
Eurosensors <10, 1996, Louvain>
Englisch
Konferenzbeitrag
Fraunhofer IMS ()
Enzym; gas; Meßaufnehmer; Mikroelektrode; Sauerstoff

Abstract
In this work a microelectrode array was used to develop a multianalyte sensor. Glucose, L-lactate and uric acid were chosen as model analytes. The array consists of ten groups of 40 microelectrodes connected in parallel, each of a size of 36 mu m. Thus the array showed a large overall current response retaining typical microelectrode features. Single rows of elecrodes were modified with enzymes entrapped in a polymer matrix. As oxidases were used as enzymes hydrogenes peroxide generated by the enzymatic reaction was detected by anodic oxidation at + 800 mV vs Ag/AgCl/3M KCl. The elementation of interferences of a NAFION membrane between the electrode surface and enzyme layer.

: http://publica.fraunhofer.de/dokumente/PX-25220.html