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Gene mutation and recombination assays

: Fahrig, R.

Alternatives to Animal Experiments in Risk Assessment. Symposium
Berlin/West: Schering, 1988
ISBN: 3-921817-35-8
Aufsatz in Buch
Fraunhofer ITA ( ITEM) ()
gene mutation; mutagenic agents; mutagenicity; mutagens; recombination

I shall describe assays which are suitable to measure gene mutations or recombinations. Apart from discussing in vitro methods as alternatives to animal experiments, I shall also emphasize ways in which the numbers of animals can be drastically reduced by defining in vivo test systems.