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Fine Particle Production by Precipitation with Compressed or Supercritical Fluids

 
: Weber, A.; Tschernjaew, J.; Beutin, M.; Kümmel, R.

Leuenberger, H.:
1st European Symposium Process Technology in Pharmaceutical and Nutritional Sciences 1998. Preprints : An event of PARTEC 98, Nürnberg - Germany, 10 - 12 March 1998
Nürnberg: NürnbergMesse GmbH, 1998
ISBN: 3-921590-55-8
S.121-130
European Symposium Process Technology in Pharmaceutical and Nutritional Sciences <1, 1998, Nürnberg>
International Congress for Particle Technology (PARTEC) <1998, Nürnberg>
Englisch
Konferenzbeitrag
Fraunhofer UMSICHT Oberhausen ()
Coprecipitation; crystallization; microcomposite; micronisation; supercritical fluid (SCF); Kofällung; Kristallisation; Mikrokomposite; Mikronisierung; überkritisches Fluid

Abstract
The aim of the present work is to work out a technical application of the PCA process and to find prerequisites for future scale-ups. Experiments were carried out to study the influence of the process conditions on the micronization of different solids as ascorbic acid, acetylsalicylic acid, urea and chloramphenicol. Further studies were made on microcomposites to check the suitability of the PCA process for complex applications.

: http://publica.fraunhofer.de/dokumente/PX-14431.html