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Disturbances of skin microcirculation in patients with chronic arterial and venous incompetence

: Creutzig, A.; Caspary, L.; Alexander, K.; Hertel, R.F.

International journal of microcirculation, Clinical and experimental 7 (1988), Nr.2, S.178
ISSN: 0167-6865
Gesellschaft für Mikrozirkulation (Jahrestagung) <11, 1987, Heidelberg>
Fraunhofer ITA ( ITEM) ()
Angiologie; angiology; blood vessel; Blutgefäß; capillary vessel; Kapillargefäß; medicine; Medizin; microcirculation; Mikrozirkulation

We studled the behaviour of tcPO2 at electrode core temperatures of 37 degree C and 44 degree C and LDF under standardized conditions in patients with peripheral arterial occlusive disease, chronic venous incampetence and with a combination of both circulatory disorders and compared the results with those of healthy volunteers. In all three patients groups severe disturbances of skin microcirculation could be observed. In the POAD group changes of areterial perfusion pressure play an important role for microcirculatory responses. When perfusion pressure is impaired by leg elevantion tcPO2 recordings are impaired, too. In contrast to healthy subjects who show a decrease of cutaneous flow when they rise form lying to standing, all patients with PAOD increased with tcPO2 (37 degree C) indicating the disturbance of integrity of this reflex. The same pattern of reactions occurs during the venous occlusion manoeuvre. Patients with CVI are mainly compromised by their venous hypertension. Leg elevation leeds to an outflow of blood from venous pools. Therefore skin capillary blood flow is increased as was shown by both methods. When venous pressure is incrased during leg dependency cutaneous blood flow is derminished. This effect is more marked than the pure vasoconstrictor response in healthy subjects. The same effect could be recorded during the venous occlusion procedure. In the third group (PAOD combined with CVI) most of the effects on skin microcirculate are paralysed by both disorders. (-y-)