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Navigation of a magnetic micro-robot through a cerebral aneurysm phantom with magnetic particle imaging

 
: Backenecker, Anna; Gladiss, Anselm von; Schwenke, Hannes; Behrends, André; Friedrich, Thomas; Lüdtke-Buzug, Kerstin; Neumann, Alexander; Barkhausen, Joerg; Wegner, Franz; Buzug, Thorsten M.

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Volltext ()

Scientific Reports 11 (2021), Art. 14082, 12 S.
ISSN: 2045-2322
Englisch
Zeitschriftenaufsatz, Elektronische Publikation
Fraunhofer IMTE ()

Abstract
Cerebral aneurysms are potentially life threatening and nowadays treated by a catheter-guided coiling or by a neurosurgical clipping intervention. Here, we propose a helically shaped magnetic micro-robot, which can be steered by magnetic fields in an untethered manner and could be applied for a novel coiling procedure. This is shown by navigating the micro-robot through an additively manufactured phantom of a human cerebral aneurysm. The magnetic fields are applied with a magnetic particle imaging (MPI) scanner, which allows for the navigation and tomographic visualization by the same machine. With MPI the actuation process can be visualized with a localization accuracy of 0.68 mm and an angiogram can be acquired both without any radiation exposure. First in-vitro phantom experiments are presented, showing an idea of a robot conducted treatment of cerebral aneurysms.

: http://publica.fraunhofer.de/dokumente/N-642830.html