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Brillouin confocal microscopy to determine biomechanical properties of SULEEI-treated bovine pericardium for application in cardiac surgery

 
: Jannasch, Anett; Rix, Jan; Welzel, Cindy; Schackert, Gabriele; Kirsch, Matthias; König, Ulla; Koch, Edmund; Matschke, Klaus; Tugtekin, Sems Malte; Dittfeld, Claudia; Galli, R.

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Clinical hemorheology and microcirculation 79 (2021), Nr.1, S.179-192
ISSN: 1386-0291
ISSN: 1875-8622
German Society for Clinical Microcirculation and Hemorheology (DGKMH Conference) <40, 2021, Senftenberg>
Englisch
Zeitschriftenaufsatz
Fraunhofer FEP ()
biomechanics; microscopy; heart valve prosthesis

Abstract
Heart valves are exposed to a highly dynamic environment and underlie high tensile and shear forces during opening and closing. Therefore, analysis of mechanical performance of novel heart valve bioprostheses materials, like SULEEI-treated bovine pericardium, is essential and usually carried out by uniaxial tensile tests. Nevertheless, major drawbacks are the unidirectional strain, which does not reflect the in vivo condition and the deformation of the sample material. An alternative approach for measurement of biomechanical properties is offered by Brillouin confocal microscopy (BCM), a novel, non-invasive and three-dimensional method based on the interaction of light with acoustic waves.

: http://publica.fraunhofer.de/dokumente/N-642616.html