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Biochip-compatible packaging and micro-fluidics for a silicon opto-electronic biosensor

 
: Ruf, H.H.; Knoll, T.; Misiakos, K.; Haupt, R.B.; Denninger, M.; Larsen, L.B.; Petrou, P.S.; Kakabakos, S.E.; Ehrentreich-Förster, E.; Bier, F.F.

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Loeschner, H.:
31st International Conference on Micro- and Nano-Engineering 2005. Proceedings : 19 - 22 September 2005, Vienna, Austria
Amsterdam: Elsevier, 2006 (Microelectronic engineering 83.2006,4/9)
S.1677-1680
International Conference on Micro- and Nano-Engineering (MNE) <31, 2005, Vienna>
Englisch
Konferenzbeitrag, Zeitschriftenaufsatz
Fraunhofer IBMT ()

Abstract
Biochip-compatible packaging for a DNA monolithic opto-electronic biosensor is presented. The packaging involves coated opto-coupler chips, ceramic carriers, plastic fluidic modules, optical alignment, self-aligned under-fill gluing as well as potting encapsulation. All the steps were implemented without denaturing the bio-molecular probes and without degrading the optical quality of the transducers. Such a packaged optical microchip was successfully employed in SNP detection.

: http://publica.fraunhofer.de/dokumente/N-59930.html