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Epigenetics - Shedding Light on the Path Ahead for Material Sciences

 
: Krüger-Genge, Anne; Mauger, Olivia; Storsberg, Joachim; Schmidt, Christian

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Volltext ()

Diseases 7 (2019), Nr.2, Art. 43, 3 S.
ISSN: 2079-9721
Englisch
Zeitschriftenaufsatz, Elektronische Publikation
Fraunhofer IAP ()

Abstract
The harmonious regulation of bodily function is a necessity for healthy individuals. Looking from the viewpoint of material sciences, one can only marvel at the cellular factories, their renewal, and the overall control of messaging and control of responses. As aging progresses and/or pathologies arise, clinicians may be forced to look for replacement of organs/tissues with medical devices. Since all devices are tailored, a detailed understanding of developmental processes, including aberrant processes leading to pathologies, is crucial to provide clinicians with a suitable device. Although research in the field of epigenetics has produced effective therapeutics and diagnostic markers, our currently fragmented understanding of epigenetic processes as they relate to material development is inherently limited, with logical implications for the success of medical procedures. Here, we illustrate how material sciences for clinical applications, critically depend on all aspects of biomedical sciences, including the field of epigenetics.

: http://publica.fraunhofer.de/dokumente/N-569746.html