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Quantitative particle uptake by cells as analyzed by different methods

: Ashraf, Sumaira; Hassan Said, Alaa; Hartmann, Raimo; Assmann, Marcus-Alexander; Feliu, Neus; Lenz, Peter; Parak, Wolfgang J.

Volltext ()

Angewandte Chemie. International edition 59 (2020), Nr.14, S.5438-5453
ISSN: 1433-7851
ISSN: 0044-8249
ISSN: 0570-0833
ISSN: 1521-3773
Deutsche Forschungsgemeinschaft DFG
PA 794/21-1
Zeitschriftenaufsatz, Elektronische Publikation
Fraunhofer EMI ()

There is a large number of two‐dimensional static in vitro studies about the uptake of colloidal nano‐ and microparticles, which has been published in the last decade. In this Minireview, different methods used for such studies are summarized and critically discussed. Supplementary experimental data allow for a direct comparison of the different techniques. Emphasis is given on how quantitative parameters can be extracted from studies in which different experimental techniques have been used, with the goal of allowing better comparison.