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Automation in the context of stem cell production - where are we heading with Industry 4.0?

 
: Kulik, Michael; Ochs, Jelena; König, Niels; Schmitt, Robert

:
Volltext urn:nbn:de:0011-n-4259979 (1.4 MByte PDF)
MD5 Fingerprint: ec76f9e3411558144b704b4ceb5b53b9
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Erstellt am: 7.8.2018


Cell & Gene Therapy Insights 2 (2016), Nr.4, S.499-506
ISSN: 2059-7800
European Commission EC
H2020-EU.3.1.3. - Treating and managing disease; 667932; AUTOSTEM
Englisch
Zeitschriftenaufsatz, Elektronische Publikation
Fraunhofer IPT ()
Automation; Automatisierung; Medizintechnik; Roboter

Abstract
As the field of cell and gene therapy continues to progress, the need for cell products for therapeutic application is increasing. In order to meet the demands, novel challenges particularly within the manufacturing of these products need to be overcome. By translating and applying automation solutions from the production industries into cell culture applications, standardized processing procedures can be introduced in order to reduce the variability, which is a critical issue within the manufacturing workflow. Additionally, the Industry 4.0 philosophy offers a variety of concepts for the design of adaptive processes that address the specific challenges in stem cell production. Novel tools such as data tracking, data analysis and machine learning are enabling technologies that will help support the safe manufacturing of effective products for future cell and gene therapies.

: http://publica.fraunhofer.de/dokumente/N-425997.html