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Analytical calibration of linear transducer arrays for photoacoustic tomography

: Öri, M.; Bost, W.; Fournelle, M.


Ntziachristos, V. ; Society of Photo-Optical Instrumentation Engineers -SPIE-, Bellingham/Wash.; Optical Society of America -OSA-, Washington/D.C.:
Opto-acoustic methods and applications in biophotonics II : 22 - 23 June 2015, Munich, Germany; part of SPIE/OSA European Conferences on Biomedical Optics
Bellingham, WA: SPIE, 2015 (Proceedings of SPIE 9539)
ISBN: 978-1-62841-704-3
Paper 95390P, 9 S.
Conference "Opto-Acoustic Methods and Applications in Biophotonics" <2, 2015, Munich>
European Conferences on Biomedical Optics (ECBO) <2015, Munich>
Fraunhofer IBMT ()
photoacoustics; ultrasound; linear transducer calibration; tomography

Tomographic photoacoustic imaging (PAT) allows to overcome the anisotropic image resolution on the position of each detector element is required. PAT systems that acquire signals from rotating linear transducer arrays come with inevitable transducer misalignments. Up to now, transducer orientation (x/y-tilt) and radial distance uncertainty were measured experimentally or have not been considered. Uncalibrated, these systems suffer from characteristic artifacts yielding misinterpretations of anatomic structures. Herein, we derive the artifact mathematically and investigate an analytical calibration method that enables the calculation and compensation of important transducer positioning parameters: the rotational radius and in-plane tilt. We studied the approach theoretically and evaluated the performance of the developed algorithm both on numerical and experimental data. A PAT system based on a 5-MHz linear transducer array, a multichannel electronics platform with channel data access, a NIR-emitting laser system and a rotating sample is used to demonstrate the benefit of the transducer calibration method providing isotropic resolution of 160 µm.