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Phase-sentitive bloch surface wave biosensors

: Sinibaldi, Alberto; Anopchenko, Aleksei S.; Rizzo, Riccardo; Michelotti, Francesco; Danz, Norbert; Munzert, Peter; Rivolo, Paola; Ricciardi, Serena; Frascella, Francesca


Institute of Electrical and Electronics Engineers -IEEE-:
18th Conference on Sensors and Microsystems, AISEM 2015 : 3-5 February 2015, Trento, Italy
Piscataway, NJ: IEEE, 2015
ISBN: 978-1-4799-8591-3
4 S.
Conference on Sensors and Microsystems (AISEM) <18, 2015, Trento>
Fraunhofer IOF ()

We report on the practical implementation of an angularly resolved ellipsometric optical sensing scheme based on Bloch surface waves sustained by tantala/titania/silica multilayers. The angular resolution is obtained by a focused illumination at fixed wavelength and detecting the angular reflectance spectrum by means of a CMOS array detector. The experimental results, obtained by using one tantala/titania/silica/multilayer defined structure, show the limit of detection below 6.5*10-7 RIU/Hz1/2. The physical characterization of the biosensors and their practical use with biological protocols is reported.