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Capillary microfluidic chip with integrated pump and valve actuator

Kapillarer Mikrofluidikchip mit integrierter Pump- und Ventilaktorik
: Große, Allyn; Geidel, Sascha; Enderlein, Tom; Groß, Stefan; Morschhauser, Andreas; Nestler, Jörg; Edelmann, Jan; Otto, Thomas; Geßner, Thomas

Chemical and Biological Microsystems Society -CBMS-, San Diego/Calif.:
18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 : San Antonio, Texas, 26-30 October 2014
San Antonio/Tex., 2014
ISBN: 978-0-9798064-7-6
International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS) <18, 2014, San Antonio/Tex.>
Fraunhofer ENAS ()
Fraunhofer IWU ()
lab-on-chip; electrolysis pump; electrolysis valve; hot embossing; laser

This paper describes the technological developments to achieve an active, disposable, microfluidic lab-on-a-chip intended to be used for the detection of glycated hemoglobin (HbA1c). The system utilizes well known technologies like hot embossing, physical vapor deposition (PVD) and laser micro structuring to realize an innovative chip concept. The complex parameter HbA1c [1] is supposed to be determined from a drop of capillary blood (5μl) after a chip internal sample preparation step. The presented work focuses on integrated liquid actuation as well as structuring and assembling technologies to develop a miniaturized chip for a large-scale production.