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Macromolecule loading into spherical, elliptical, star-like and cubic calcium carbonate carriers

: Parakhonskiy, B.V.; Yashchenok, A.M.; Donatan, S.; Volodkin, D.V.; Tessarolo, F.; Antolini, R.; Möhwald, H.; Skirtach, A.G.


ChemPhysChem 15 (2014), Nr.13, S.2817-2822
ISSN: 1439-4235
ISSN: 1439-7641
Fraunhofer IBMT ()

We fabricated calcium carbonate particles with spherical, elliptical, star-like and cubical morphologies by varying relative salt concentrations and adding ethylene glycol as a solvent to slow down the rate of particle formation. The loading capacity of particles of different isotropic (spherical and cubical) and anisotropic (elliptical and star-like) geometries is investigated, and the surface area of such carriers is analysed. Potential applications of such drug delivery carriers are highlighted.