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Bioassays: Humane 3D-in vitro-Testsysteme für die präklinische Forschung

Bioassays: Human 3D in vitro test systems for preclinical research
 
: Rossi, A.; Fecher, D.; Egner, S.; Schweinlin, M.; Steinke, M.; Walles, H.

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Biospektrum 20 (2014), Nr.4, S.404-406
ISSN: 0947-0867
ISSN: 1868-6249
Deutsch
Zeitschriftenaufsatz
Fraunhofer IGB ()

Abstract
In vitro test systems have to be optimized to reduce preclinical failure rates. Therefore, we have introduced a new innovative system which mimics physiological conditions and enables vascularisation in bioreactors. Thus, we have developed test systems for intestinal uptake studies, for airway infections and for different tumour entities, e. g. lung cancer. A further approach presents the ex vivo cornea test system for irritation studies.

: http://publica.fraunhofer.de/dokumente/N-301355.html