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Label-free immobilization of nano-particles on silicon based electrodes for single-biomolecule studies

 
: Wenger, C.

Institute for Systems and Technologies of Information, Control and Communication -INSTICC-, Setubal:
7th International Conference on Biomedical Electronics and Devices, BIODEVICES 2014 : 3rd to 6th March 2014, Angers, France, part of BIOSTEC, the International Joint Conference on Biomedical Engineering Systems and Technologies
SciTePress, 2014
ISBN: 978-989-7580-13-0
S.176-180
International Conference on Biomedical Electronics and Devices (BIODEVICES) <7, 2014, Angers>
International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC) <7, 2014, Angers>
Englisch
Konferenzbeitrag
Fraunhofer IBMT ()

Abstract
Dielectrophoresis (DEP) is an established method for the spatial manipulation of microscopical particles. We demonstrate the temporal and permanent immobilization of polystyrene nanoparticles and protein molecules with sizes ranging from 4 nm to 500 nm. For this, regular arrays of silicon based nanoelectrodes were developed with tip diameters of 10 nm and 50 nm. No chemical modifications of molecules, particles or surfaces were needed. This opens up potentially important applications of DEP in biosensing and cell research.

: http://publica.fraunhofer.de/dokumente/N-301105.html