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Label-free biosensor based on an all-polymer DFB laser

: Heydari, E.; Buller, J.; Wischerhoff, E.; Laschewsky, A.; Döring, S.; Stumpe, J.


Advanced optical materials 2 (2014), Nr.2, S.137-141
ISSN: 2195-1071
Fraunhofer IAP ()

A monolithic active optical resonator biosensor is fabricated for label-free sensing. The all-polymer sensor consists of a polymer distributed feedback (DFB) laser and a hydrogel recognition layer. Specific binding of analyte modulates the effective refractive index, shifting the laser emission wavelength. Real time detection of avidinbiotin interactions is demonstrated as a model for the new label-free biosensing principle.