Publica
Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten. Human immune system in a microtiter plate
Innate immune assay for the examination of receptor activity
| GIT laboratory journal Europe (2011), Nr.3-4, S.10-11
ISSN: 1611-6038
ISSN: 1434-2634 |
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| Englisch |
| Zeitschriftenaufsatz, Elektronische Publikation |
| Fraunhofer IGB () |
Abstract
Pattern recognition receptors (PRRs) are the first defense line of the innate immune system. In the last years PRRs had been studied in different ways resulting in a lot of new insights. However, it was not possible to investigate individual combinations of PRRs and their specific ligands because of the complex network in immune signaling. A cell-based assay developed at Fraunhofer IGB allows a direct way to detect the activity of individual human PRR-receptors in a highly specific way.