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Prostate cancer detection by laser induced autofluorescence and multicomponent spectroscopy

: Salomon, G.; Hess, T.; Erbersdobler, A.; Eichelberg, C.; Greschnerd, S.; Sobchuk, A.N.; Korolik, A.K.; Nemkovich, N.A.; Schreiber, J.; Herms, M.; Graefen, M.; Huland, H.


Panchenko, V. ; National Academy of Sciences of Belarus:
Laser technologies for medicine : International Conference on Lasers, Applications, and Technologies 2007, LAT 2007. 28 May - 1 June 2007, Minsk, Belarus
Bellingham, WA: SPIE, 2007 (SPIE Proceedings 6734)
ISBN: 978-0-8194-6892-5
ISSN: 0038-7355
Paper 67340H
International Conference on Lasers, Applications, and Technologies (LAT) <2007, Minsk>
Fraunhofer IZFP, Institutsteil Dresden ( IKTS-MD) ()

Laser-Induced-Autofluorescence (LIAF), White-Light-Remission (WLR) and Electrical-Impedance-Measurement (ElM) in combination with principal component analysis were used at first time for differentiation benign from malignant prostatic tissue in vitro. The used complex statistical processing of the data has shown a differentiation of benign and malignant prostatic tissue with a sensitivity of 93.8% and a specificity of 92.4%.