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Validation of 3D ultrasound - CT registration of prostate images

: Firle, E.; Wesarg, S.; Karangelis, G.; Dold, C.


Sonka, M. ; Society of Photo-Optical Instrumentation Engineers -SPIE-, Bellingham/Wash.:
Medical imaging 2003. Image processing : 17 - 20 February 2003, San Diego, California, USA
Bellingham/Wash.: SPIE, 2003 (SPIE Proceedings Series 5032)
ISBN: 0-8194-4833-8
Medical Imaging Symposium <2003, San Diego/Calif.>
Fraunhofer IGD ()
image registration; computer tomography; 3D Ultrasound; Brachytherapy

All over the world 20% of men are expected to develop prostate cancer sometime in his life. In addition to surgery - being the traditional treatment for cancer - the radiation treatment is getting more popular. The most interesting radiation treatment regarding prostate cancer is Brachytherapy radiation procedure. For the safe delivery of that therapy imaging is critically important. In several cases where a CT device is available a combination of the information provided by CT and 3D Ultrasound (U/S) images o.ers advantages in recognizing the borders of the lesion and delineating the region of treatment. For these applications the CT and U/S scans should be registered and fused in a multi-modal dataset. Purpose of the present development is a registration tool (registration, fusion and validation) for available CT volumes with 3D U/S images of the same anatomical region, i.e. the prostate. The combination of these two imaging modalities interlinks the advantages of the high-resolution CT imaging and low cost real-time U/S imaging and o.ers a multi-modality imaging environment for further target and anatomy elineation. This tool has been integrated into the visualization software "InViVo" which has been developed over several years in Fraunhofer IGD in Darmstadt.