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Highly-integrated, low-cost in-vitro diagnostic platform for miniaturized assay development

 
: Nestler, J.; Morschhauser, A.; Otto, T.; Koger, B.; Brandenburg, A.; Wunderlich, K.; Ehrentreich-Förster, E.; Bier, F.F.; Gessner, T.

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Volltext (PDF; )

Verpoorte, S. (Hrsg.) ; Chemical and Biological Microsystems Society -CBMS-, San Diego/Calif.:
14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010 (MicroTAS 2010). Vol.2 : Groningen, The Netherlands, 3 - 7 October 2010
Red Hook, NY: Curran, 2011
ISBN: 978-1-61839-062-2
S.1223-1225
International Conference on Miniaturized Systems for Chemistry and Life Sciences <14, 2010, Groningen>
Englisch
Konferenzbeitrag, Elektronische Publikation
Fraunhofer ENAS ()
Fraunhofer IPM ()
Fraunhofer IBMT ()

Abstract
The paper describes a low-cost microfluidic platform with integrated micropumps and optical biosensor for the development of miniaturized assays for in-vitro diagnostic and point-of-care applications. The platform consists of disposable microfluidic cartridges incorporating all parts necessary for carrying out immunoassays (including reagents) as well as a readout instrument providing both the optical, fluorescence based readout and the electrical interface for pump control. The feasibility of the system for running immunoassays is demonstrated by a CRP and PSA based assay carried out completely inside such a cartridge.

: http://publica.fraunhofer.de/dokumente/N-167518.html