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Bioreactor for the conversion of an educt to a product using an biocatalyst, which is reversibly immobilized on and/or in a controllable carrier material, comprises tubular reactor chamber, and supporting body that is part of reactor wall
 
: Deerberg, G.; Wack, H.; Nellesen, A.; Schwarze-Benning, K.

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Frontpage ()

DE 102009020698 A1: 20090511
DE 102010020231 A: 20100511
C12M0001
Deutsch
Patent, Elektronische Publikation
Fraunhofer UMSICHT Oberhausen ()

Abstract
DE 102010020231 A1 UPAB: 20101130 NOVELTY - The bioreactor (1) for the conversion of an educt to a product using an biocatalyst, which is reversibly immobilized on and/or in a controllable carrier material (3), comprises a tubular reactor chamber (2), and a supporting body, which is a part of a reactor wall and/or a mounting part and a filling body arranged in the bioreactor during the catalyzed reaction. The carrier material is bound on the surface of the supporting body, and forms a microscale surface layer of the supporting body, where the layer thickness of the microscale surface layer is 20 mu m or less. DETAILED DESCRIPTION - The bioreactor (1) for the conversion of an educt to a product using an biocatalyst, which is reversibly immobilized on and/or in a controllable carrier material (3), comprises a tubular reactor chamber (2), and a supporting body, which is a part of a reactor wall and/or a mounting part and a filling body arranged in the bioreactor during the catalyzed reaction. The carrier material is bound on the surface of the supporting body, and forms a microscale surface layer of the supporting body, where the layer thickness of the microscale surface layer is 20 mu m or less. The carrier material forms a nanoscale surface layer of the supporting body, and is chemically, physically and/or mechanically fixed. The carrier material is fixed to an inner lateral surface of the reactor wall limiting the reactor chamber. The carrier material is bound on a cell fabric, polyethylene film or polypropylene film. The release of the biocatalyst by and/or from the carrier material or the immobilization of the biocatalyst on and/or in the carrier material is controllable by a change of the environmental conditions of the carrier material. The carrier material is fixed onto the supporting body for increasing the mechanical stability on and/or in the supporting body with high mass stability of the carrier material. USE - Bioreactor for the conversion of an educt to a product using a biocatalyst for the chemical and pharmaceutical industry. ADVANTAGE - The bioreactor ensures simple and cost-effective conversion of the educt to the product with high mechanical stability and high service life, and reduces the formation of unwanted by-products, emissions and waste materials.

: http://publica.fraunhofer.de/dokumente/N-148669.html