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Mesoporous indium tin oxide as a novel platform for bioelectronics

 
: Frasca, S.; Graberg, T. von; Feng, J.-J.; Thomas, A.; Smarsly, B.M.; Weidinger, I.M.; Scheller, F.W.; Hildebrandt, P.; Wollenberger, U.

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ChemCatChem 2 (2010), Nr.7, S.839-845
ISSN: 1867-3880
ISSN: 1867-3899
Englisch
Zeitschriftenaufsatz
Fraunhofer IBMT ()

Abstract
Stable immobilization and reversible electrochemistry of cytochrome c in a tranparent indium tin oxide film with a well-defined mesoporosity (mpITO) is demonstrated. the transparency and good conductivity, in combination with the large surface area of mpITO, allow the incorporation of a high amount of elelctroactive biomolecules and their electrochemical and spectroscopic investigation. UV/Vis and resonance Raman spectroscopy, in combination with direct protein voltammetry are employed for the characterization of cytochrome c immobilized in the mpITO and reveal no perturbant of the structural of the integrity of the redox protein. The potential of this modified material as a biosensor detection of superoxide anions is also demonstrated.

: http://publica.fraunhofer.de/dokumente/N-142828.html