Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.

Mesoporous indium tin oxide as a novel platform for bioelectronics

: Frasca, S.; Graberg, T. von; Feng, J.-J.; Thomas, A.; Smarsly, B.M.; Weidinger, I.M.; Scheller, F.W.; Hildebrandt, P.; Wollenberger, U.


ChemCatChem 2 (2010), Nr.7, S.839-845
ISSN: 1867-3880
ISSN: 1867-3899
Fraunhofer IBMT ()

Stable immobilization and reversible electrochemistry of cytochrome c in a tranparent indium tin oxide film with a well-defined mesoporosity (mpITO) is demonstrated. the transparency and good conductivity, in combination with the large surface area of mpITO, allow the incorporation of a high amount of elelctroactive biomolecules and their electrochemical and spectroscopic investigation. UV/Vis and resonance Raman spectroscopy, in combination with direct protein voltammetry are employed for the characterization of cytochrome c immobilized in the mpITO and reveal no perturbant of the structural of the integrity of the redox protein. The potential of this modified material as a biosensor detection of superoxide anions is also demonstrated.