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Bioactive surfaces based on PEG

An AFM charakterization of novel thermo-responsive surfaces
: Schmidt, S.; Kessel, S.; Wischerhoff, E.; Laschewsky, A.; Lutz, J.-F.; Uhlig, K.; Lankenau, A.; Duschl, C.; Fery, A.

Imaging & microscopy 12 (2010), Nr.1, S.40-42
ISSN: 1439-4243
ISSN: 1863-7809
Fraunhofer IAP ()

The control over cell-surface interactions is a highly important issue for biomedical and biotechnology applications. Novel thermoresponsive PEG (Polyethylene glycol) surface coatings allow convenient control over the cell adhesion and do not interfere with membrane proteins. Here we benchmark the ability of the surfaces to control cell adhesion and quantify the interfacial interactions via colloidal probe atomic force microscopy (AFM).